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APAD is an NAD analog with higher oxidation potential than NAD. It can substitute for NAD as a hydrogen-accepting cofactor in many dehydrogenase reactions; e.g. lactate dehydrogenase from Toxoplasma, Clonorchis, and Plasmodium, bacterial lipoamide dehydrogenase, as well as mammalian dehydrogenases. It can also act as a proton acceptor in various transhydrogenation reactions with NADH or NADPH. Group: Biochemicals. Alternative Names: APAD; adenosine 5'-(trihydrogen diphosphate), P?5-ester with 3-acetyl-1- β -D-ribofuranosyl pyridinium , inner salt. Grades: Purified. CAS No. 86-08-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C22H28N6O14P2, Molecular Weight: 662.44. US Biological Life Sciences.
3-Acetylpyridine adenine dinucleotide is an NAD analog with higher oxidation potential than NAD. It can substitute for NAD as a hydrogen-accepting cofactor in many dehydrogenase reactions. For example lactate dehydrogenase from Toxoplasma, Clonorchis, and Plasmodium, bacterial lipoamide dehydrogenase, as well as mammalian dehydrogenases. This compound can also act as a proton acceptor in various transhydrogenation reactions with NADH or NADPH. Group: Coenzymes. Synonyms: aldehyde reductase; ADH; alcohol dehydrogenase (NAD); aliphatic alcohol dehydrogenase; ethanol dehydrogenase; NAD-dependent alcohol dehydrogenase; NA. Enzyme Commission Number: EC 1.1.1.1. CAS No. 1986-8-8. Purity: Determined by increase in absorbance at 363 nm on enzymatic reduction with ADH* at pH 10.0 > 92% *ADH = Alcohol dehydrogenase (Horse liver) (EC 1.1.1.1.). APAD. Mole weight: 662.44. Storage: Keep tightly stoppered in the dark below 5°C. Moisture will reduce the purity. For prolonged storage, keep below-20°C. aldehyde reductase; ADH; alcohol dehydrogenase (NAD); aliphatic alcohol dehydrogenase; ethanol dehydrogenase; NAD-dependent alcohol dehydrogenase; NAD-specific aromatic alcohol dehydrogenase; NADH-alcohol dehydrogenase; NADH-aldehyde dehydrogenase; primary alcohol dehydrogenase; yeast alcohol dehydrogenase; EC 1.1.1.1; APAD. Cat No: NATE-0077.
Estradiol benzoate
Estradiol benzoate (β-Estradiol 3-benzoate) is a HBx protein inhibitor and inhibits androgen and hepatitis B virus (HBV) transcription, replication. Estradiol benzoate shows antifertility effects, anti- Toxoplasma gondii activity and can improve memory behavior of Ovariectomy (Ovx) female mice [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: β-Estradiol 3-benzoate; 17β-Estradiol 3-benzoate. CAS No. 50-50-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B1192.
Estradiol benzoate (Standard)
Estradiol benzoate (Standard) is the analytical standard of Estradiol benzoate. This product is intended for research and analytical applications. Estradiol benzoate (β-Estradiol 3-benzoate) is a HBx protein inhibitor and inhibits androgen and hepatitis B virus (HBV) transcription, replication. Estradiol benzoate shows antifertility effects, anti- Toxoplasma gondii activity and can improve memory behavior of Ovariectomy (Ovx) female mice [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 50-50-0. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B1192R.
Estragole
Estragole (4-Allylanisole) is a relatively nontoxic volatile terpenoid ether and major component of the essential oil from many plants. Estragole significantly triggers Apoptosis , suppresses LPS-induced intracellular ROS production. Estragole activats Nrf-2 and regulates NF-κB. Estragole has anti-toxoplasma, anti-inflammatory, anti-edema, antioxidant and immunomodulatory properties. Estragole blocks DRG neuron excitability. Estragole has improves gastric ulcer activity [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11] [12] [13]. Uses: Scientific research. Group: Natural products. Alternative Names: 4-Allylanisole. CAS No. 140-67-0. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-N5060.
JCP174
JCP174 is a depalmitoylase inhibitor that targets TgPPT1. JCP174 enhances Toxoplasma tachyzoite invasion into BSC-1 host cells. Synonyms: 7-amino-4-chloro-3-Propoxyisocoumarin; 7-Amino-4-chloro-3-propoxy-1H-isochromen-1-one. Grades: ≥98%. CAS No. 126062-19-9. Molecular formula: C12H12ClNO3. Mole weight: 253.7.
Oxytetracycline
Oxytetracycline is a glycoside antibiotic produced by the strain of Streptomyces xanthophaeus. It can be used for infections caused by Gram-positive bacteria, Gram-negative bacteria, Mycoplasma, Chlamydia, Rickettsia and other pathogens. Especially for the prevention and treatment of porcine eperythropoiesis, toxoplasma, chlamydia and other pathogen infections. Synonyms: Doxycycline hyclate EP impurity E; Doxycycline monohydrate EP impurity E; Oxytetracycline; Doxycycline EP impurity E; Terramycin; Oxyterracine; Oxytetracyclin; 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6S,12aS)-; (4S,4aR,5S,5aR,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide; 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, [4S-(4α, 4aα, 5α, 5aα, 6β, 12aα)]-; 5-Hydroxytetracycline; Abbocin; Adamycin; Antibiotic TM 25; Berkmycen; Biostat PA; Clinimycin; Dabicycline; Erfamycin; Fanterrin; Geomycin (Streptomyces vimosus); Geotilin; Imperacin; Lenocycline; NSC 9169; Oksisyklin; Ryomycin; Solkaciclina; Tormicina; Ursocycline; Vendarcin. Grades: >98%. CAS No. 79-57-2. Molecular formula: C22H24N2O9. Mole weight: 460.43.
Pyrimethamine
Dihydrofolate reductase inhibitor; generally used in combination with other antimicrobial agents. Antiprotozoal (Toxoplasma); antimalarial. Group: Biochemicals. Alternative Names: 5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine; 2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine; Chloridin; Chloridine; Daraprim; Khloridin; Malocide; Pirimecidan; Pirimetmin; NSC 3061; RP 4753. Grades: Highly Purified. CAS No. 58-14-0. Pack Sizes: 100mg, 500mg, 1g. Molecular Formula: C12H13ClN4. US Biological Life Sciences.
Worldwide
Pyrimethamine-d3
Dihydrofolate reductase inhibitor; generally used in combination with other antimicrobial agents. Antiprotozoal (Toxoplasma); antimalarial. Group: Biochemicals. Alternative Names: 5-(4-Chlorophenyl)-6-ethyl-d3-2,4-pyrimidinediamine; 2,4-Diamino-5-(4-chlorophenyl)-6-ethyl-d3-pyrimidine; Chloridin-d3; Chloridine-d3; Malocide-d3; Pirimecidan-d3; Pirimetamin-d3; NSC 3061-d3; RP 4753-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
rhomboid protease
These endopeptidases are multi-spanning membrane proteins. Their catalytic site is embedded within the membrane and they cleave type-1 transmembrane domains. A catalytic dyad is involved in proteolysis rather than a catalytic triad, as was thought previously. They are important for embryo development in Drosophila melanogaster. Rhomboid is a key regulator of EGF receptor signalling and is responsible for cleaving Spitz, the main ligand of the Drosophila EGF receptor pathway. Belongs in peptidase family S54. Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite. Rhomboids are widely conserved from bacteria to archaea to humans. Group: Enzymes. Enzyme Commission Number: EC 3.4.21.105. CAS No. 713145-02-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4100; rhomboid protease; EC 3.4.21.105; 713145-02-9. Cat No: EXWM-4100.
Spiramycin
Spiramycin (Rovamycin) is a macrolide antibiotic produced by Streptomyces ambofaciens with against bacteria and Toxoplasma gondii activities, and also has antiparasitic effect. Spiramycin is composed of a 16-member lactone ring, on which three sugars (mycaminose, forosamine, and mycarose) are attached [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Rovamycin. CAS No. 8025-81-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-100593.
Sulfathiazole
Sulfathiazole is an organosulfur compound that has been used as a short-acting sulfa drug. It can be mainly used for the treatment of digestive tract, respiratory tract infections, mastitis, endometritis and other diseases caused by sensitive bacteria in domestic animals, and it can also be used for toxoplasma infection. Uses: Anti-infective agents. Synonyms: HSDB4380; HSDB-4380; HSDB 4380; Sulfathiazole; Planomide; Poliseptil. Grades: >98%. CAS No. 72-14-0. Molecular formula: C9H9N3O2S2. Mole weight: 255.32.
Trimetrexate
Trimetrexate (CI-898) is an antibiotic , also a potent and orally active dihydrofolate reductase (DHFR) inhibitor, reducing the production of DNA and RNA precursors and leading to cell death, with IC 50 values of 4.74 nM and 1.35 nM for human DHFR and Toxoplasma gondii DHFR. Trimetrexate can also inhibit the growth of various cancer cells. Trimetrexate can be used for researching Pneumocystis carinii pneumonia (PCP) and cancer [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CI-898. CAS No. 52128-35-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10373.
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