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Bis(2,4,6-trichlorophenyl) oxalate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1165-91-9. Pack Sizes: 1 g; 5 g. Product ID: HY-W042438.
A cell-permeable phenylhydrazone that restores mitochondrial tubular network formation in MEF lacking either of the two outer mitochondrial membrane (OMM) mitofusins (EC50=5.3 and 4.42 mM, respectively, in Mfn1 or Mfn2 knockout MEF cells) or in MPP+-treated SH-SY5Y cells (5uM 24h), but not in MEF lacking both Mfn1/2 or the inner mitochondrial membrane (IMM) fusion mediator Opa1 (optic atrophy1). M1 (5uM 24h) is reported to boost the downregulated ATP5A & ATP5B protein level in Mfn1 or Mfn2 knockout MEF to the wild-type MEF level and ATPase inhibitor oligomycin at 5uM is shown to completely offset the mitochondrial fusion effect by 5uM M1 in Mfn1 knockout MEF. Comparing to mdivi-1, M1 exerts its effect via promoting fusion rather than inhibiting fission or division. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
N-(4-Pyridyl)-N'-(2,4,6-trichlorophenyl)urea. Group: Biochemicals. Alternative Names: N-4-Pyridinyl-N'-(2,4,6-trichlorophenyl)urea. Grades: Highly Purified. CAS No. 97627-27-5. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C12H8Cl3N3O. US Biological Life Sciences.
Worldwide
N-(4-Pyridyl)-N-(2,4,6-trichlorophenyl)urea
A pyridyl urea compound that acts as a potent, selective, and ATP-competitive inhibitor of Rho-associated protein kinase. Group: Biochemicals. Alternative Names: N-4-Pyridinyl-N-(2,4,6-trichlorophenyl)urea. Grades: Highly Purified. CAS No. 97627-27-5. Pack Sizes: 5mg. US Biological Life Sciences.
DS-1001b is an oral selective inhibitor of mutant IDH1 R132X with potential antineoplastic activity and is designed to penetrate the blood-brain barrier. Group: Fluorinated apis. Alternative Names: 2-Methylpropan-2-amine (E)-3-(1-(5-(2-fluoropropan-2-yl)-3-(2,4,6-trichlorophenyl)isoxazole-4-carbonyl)-3-methyl-1H-indol-4-yl)acrylate; Safusidenib erbumine. CAS No. 1898207-64-1. Molecular formula: C29H29Cl3FN3O4. Mole weight: 608.92. Appearance: White to off-white solid powder. Purity: >98%. IUPACName: (E)-3-[1-[5-(2-fluoropropan-2-yl)-3-(2,4,6-trichlorophenyl)-1,2-oxazole-4-carbonyl]-3-methylindol-4-yl]prop-2-enoic acid;2-methylpropan-2-amine. Catalog: OFC1898207641.
Elpetrigine
Elpetrigine, also known as GW 273293 and JZP-4, has a blocking effect on calcium channels and potassium channels which has been in clinical bipolar disorders and epilepsy. Synonyms: 3-(2,3,5-trichlorophenyl)pyrazine-2,6-diamine; GW273293; GW-273293; GW 273293; JZP-4; JZP 4; JZP4; Elpetrigine. Grades: >98%. CAS No. 212778-82-0. Molecular formula: C10H7Cl3N4. Mole weight: 289.54.
Haloprogin
Haloprogin is an antifungal drug. It can be used for the treatment of athlete's foot and other fungal infections. Uses: Athlete's foot and other fungal infections. Synonyms: M 1028; NSC 100071; M1028; NSC100071; M-1028; NSC-100071; 1,2,4-Trichloro-5-[(3-iodo-2-propynyl)oxy]benzene; 2,4,5-Trichlorophenyl γ-Iodopropargyl Ether; 3-Iodo-2-propynyl 2,4,5-Trichlorophenyl Ether; 1,2,4-Trichloro-5-[(3-iodo-2-propyn-1-yl)oxy]benzene. Grades: 98%. CAS No. 777-11-7. Molecular formula: C9H4Cl3IO. Mole weight: 361.39.
Lotilaner
Lotilaner is an insecticide and veterinary drug. It acts as a non-competitive antagonist of insects GABA receptors. Uses: An insecticide and veterinary drug. Synonyms: (S)-3-methyl-N-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-5-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)thiophene-2-carboxamide. Grades: 98%. CAS No. 1369852-71-0. Molecular formula: C20H14Cl3F6N3O3S. Mole weight: 569.75.
NBI-27914
NBI-27914 is antagonist of the CRF1 and CRF2 recepetors (Corticotropin-releasing factor). Synonyms: 5-chloro-4-N-(cyclopropylmethyl)-2-methyl-4-N-propyl-6-N-(2,4,6-trichlorophenyl)pyrimidine-4,6-diamine; 2-methyl-4-(N-propyl-N-cycloproanemethylamino)-5-chloro-6-(2,4,6-trichloranilino)pyrimidine; NBI 27914; NBI27914. Grades: >99 %. CAS No. 184241-44-9. Molecular formula: C18H20Cl4N4. Mole weight: 434.186.
NBI 27914 hydrochloride
NBI 27914 hydrochloride is a corticotropin-releasing factor1 receptor antagonist. It can block behavioral seizures in vivo. Synonyms: NBI 27914 hydrochloride; NBI27914 hydrochloride; NBI-27914 hydrochloride; 5-Chloro-N-(cyclopropylmethyl)-2-methyl-N-propyl-N'-(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine hydrochloride. Grades: ≥99% by HPLC. CAS No. 1215766-76-9. Molecular formula: C18H20Cl4N4.HCl. Mole weight: 470.66.
Pf-01247324
PF-01247324 is a subtype-selective Nav1.8 blocker, for study cerebellar dysfunction in MS and related disorders. Uses: Pf-01247324 is a selective nav 1.8 channel blocker. Synonyms: 6-amino-N-methyl-5-(2,3,5-trichlorophenyl)picolinamide; PF 01247324. Grades: 98%. CAS No. 875051-72-2. Molecular formula: C13H10Cl3N3O. Mole weight: 330.60.
Phenyltrichlorosilane appears as a colorless liquid with a pungent odor. Decomposed by moisture or water to hydrochloric acid with evolution of heat. Corrosive to metals and tissue.;Liquid. Group: Silane coupling agentsself assembly and contact printing materials. Alternative Names: Trichlorophenylsilane; Phenyl chloride silicide. CAS No. 98-13-5. Product ID: trichloro(phenyl)silane. Molecular formula: 211.54. Mole weight: C6H5Cl3Si. C1=CC=C(C=C1)[Si](Cl)(Cl)Cl. InChI=1S/C6H5Cl3Si/c7-10(8, 9)6-4-2-1-3-5-6/h1-5H. ORVMIVQULIKXCP-UHFFFAOYSA-N. >98% (GC).
PSB 10 hydrochloride
PSB 10 is a potent and highly selective antagonist for the human adenosine A3 receptor that displays > 17000-fold selectivity over other adenosine receptors (Ki values are 0.553, > 10000, > 10000 and > 10000 nM for A2B, A1, A2A and A3 receptors respectively). It produces thermal hyperalgesia in mice in vivo. Synonyms: PSB 10 hydrochloride; PSB10 hydrochloride; PSB-10 hydrochloride; 8-Ethyl-1,4,7,8-tetrahydro-4-methyl-2-(2,3,5-trichlorophenyl)-5H-imidazo[2,1-i]purin-5-one monohydrochloride. Grades: ≥98% by HPLC. CAS No. 591771-91-4. Molecular formula: C16H14Cl3N5O.HCl. Mole weight: 435.14.
Sipatrigine is a blocker of voltage-dependent sodium channels (NaV) and a glutamate release inhibitor. Sipatrigine exhibits neuroprotective activity in rat models of cerebral ischemia. It was also reported to block Ca2+ channels. Uses: Neuroprotective agents. Synonyms: 619C; 619C-89; BW-619C-89; BW-619C89; 619 C; 619C 89; BW 619C-89; BW 619C89; 619C; 619C89; BW619C89; 2-(4-Methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)-4-pyrimidinamine. Grades: ≥99% by HPLC. CAS No. 130800-90-7. Molecular formula: C15H16Cl3N5. Mole weight: 372.68.
Tetradifon
Heterocyclic Organic Compound. Alternative Names: P-CHLOROPHENYL-2,4,5-TRICHLOROPHENYL SULFONE;TETRADIFON;TEDION;TEDION V-18;TEDION V-18(R);TEDONE;1,2,4-trichloro-5-((4-chlorophenyl)sulfonyl)-benzen;1,2,4-trichloro-5-((4-chlorophenyl)-sulfonyl)benzene. CAS No. 116-29-0. Molecular formula: C12H6Cl4O2S. Mole weight: 356.05. Catalog: ACM116290.
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