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| Product | Description | |
|---|---|---|
| Tubulin, GST tagged human | recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. |  |
| tubulin GTPase | An intrinsic activity of α-tubulin involved in tubulin folding, division plane formation in prokaryotic cells and others. Group: Enzymes. Enzyme Commission Number: EC 3.6.5.6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4717; tubulin GTPase; EC 3.6.5.6. Cat No: EXWM-4717. |  |
| Tubulin Inhibitor 6 | Tubulin inhibitor 6 is a tubulin inhibitor and an effective inhibitor of a variety of cancer cell lines. Synonyms: IHAP1; 2-Chloro-10-(4-Methoxybenzoyl)-10H-Phenothiazine; (2-Chloro-10H-Phenothiazin-10-Yl)(4-Methoxyphenyl)Methanone; Oprea1_789892. Grades: 98%. CAS No. 105925-39-1. Molecular formula: C20H14ClNO2S. Mole weight: 367.8. |  |
| tubulin-tyrosine ligase | L-Tyrosine is linked via a peptide bond to the C-terminus of de-tyrosinated α-tubulin (des-Tyrω-α-tubulin). The enzyme is highly specific for α-tubulin and moderately specific for ATP and L-tyrosine. L-Phenylalanine and 3,4-dihydroxy-L-phenylalanine are transferred but with higher Km values. Group: Enzymes. Enzyme Commission Number: EC 6.3.2.25. CAS No. 60321-03-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5743; tubulin-tyrosine ligase; EC 6.3.2.25; 60321-03-1. Cat No: EXWM-5743. | |
| tubulinyl-Tyr carboxypeptidase | Active at neutral pH, from brain. Group: Enzymes. Synonyms: carboxypeptidase-tubulin; soluble carboxypeptidase; tubulin-tyrosine carboxypeptidase; tubulin carboxypeptidase; tubulinyltyrosine carboxypeptidase; tyrosinotubulin carboxypeptidase; tyrosyltubulin carboxypeptidase; TTCPase; brain I carboxypeptidase. Enzyme Commission Number: EC 3.4.17.17. CAS No. 73050-23-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4069; tubulinyl-Tyr carboxypeptidase; EC 3.4.17.17; 73050-23-4; carboxypeptidase-tubulin; soluble carboxypeptidase; tubulin-tyrosine carboxypeptidase; tubulin carboxypeptidase; tubulinyltyrosine carboxypeptidase; tyrosinotubulin carboxypeptidase; tyrosyltubulin carboxypeptidase; TTCPase; brain I carboxypeptidase. Cat No: EXWM-4069. | |
| α-tubulin N-acetyltransferase | The enzyme from Chlamydomonas flagella also acetylates mammalian brain α-tubulin. Group: Enzymes. Synonyms: α-tubulin acetylase; TAT; α-tubulin acetyltransferase; tubulin N-acetyltransferase; acetyl-CoA:α-tubulin-L-lysine N-acetyltransferase; acetyl-CoA:[α-tubulin]-L-lysine 6-N-acetyltransferase. Enzyme Commission Number: EC 2.3.1.108. CAS No. 99889-90-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2046; α-tubulin N-acetyltransferase; EC 2.3.1.108; 99889-90-4; α-tubulin acetylase; TAT; α-tubulin acetyltransferase; tubulin N-acetyltransferase; acetyl-CoA:α-tubulin-L-lysine N-acetyltransferase; acetyl-CoA:[α-tubulin]-L-lysine 6-N-acetyltransferase. Cat No: EXWM-2046. | |
| Anti-?-Tubulin (AK-15) antibody produced in rabbit | IgG fraction of antiserum, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-?-Tubulin antibody, Mouse monoclonal | clone AA13, purified from hybridoma cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-?-Tubulin antibody, Mouse monoclonal | clone DM1A, purified from hybridoma cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Tubulin antibody produced in rabbit | whole antiserum. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-?-Tubulin (DQ-19) antibody produced in rabbit | IgG fraction of antiserum, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-?-Tubulin?FITC antibody, Mouse monoclonal | clone DM1A, purified from hybridoma cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-?-Tubulin from chicken | affinity isolated antibody, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-?-Tubulin II antibody, Mouse monoclonal | clone 7B9, purified from hybridoma cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-?-Tubulin (LL-17) antibody produced in rabbit | affinity isolated antibody, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-?-Tubulin (QG-17) antibody produced in rabbit | affinity isolated antibody, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-Acetylated Tubulin antibody produced in mouse | clone 6-11B-1, purified from hybridoma cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-Tubulin, Acetylated antibody produced in mouse | clone 6-11B-1, ascites fluid. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-?-Tubulin antibody produced in mouse | clone D66, purified from hybridoma cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-?-Tubulin antibody produced in mouse | clone DM1A, ascites fluid. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-?-Tubulin antibody produced in mouse | clone TUB-11, purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-?-Tubulin?Cy3 antibody produced in mouse | clone TUB 2.1, purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-?-Tubulin?FITC antibody produced in mouse | clone TUB 2.1, purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-?-Tubulin I antibody produced in mouse | clone SAP.4G5, ascites fluid. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-?-Tubulin I+II antibody produced in mouse | clone JDR.3B8, ascites fluid. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-?-Tubulin III antibody produced in mouse | clone SDL.3D10, ascites fluid. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-?-Tubulin III (neuronal) antibody produced in mouse | ~1.0 mg/mL, clone 2G10, purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-?-Tubulin Isotype III antibody produced in mouse | clone SDL.3D10, purified from hybridoma cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-?-Tubulin IV antibody produced in mouse | clone ONS.1A6, ascites fluid. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-Tubulin, Polyglutamylated antibody produced in mouse | clone B3, purified from hybridoma cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-Tubulin, Tyrosine antibody produced in mouse | clone TUB-1A2, ascites fluid. Group: Fluorescence/luminescence spectroscopy. | |
| 10-(Chloroacetyl)-10H-phenothiazine | 10-(Chloroacetyl)-10H-phenothiazine is useful in the synthesis of phenstatin analogues which exhibits anti-proliferative activity and interaction with tubulin. Group: Biochemicals. Grades: Highly Purified. CAS No. 786-50-5. Pack Sizes: 100mg, 500mg. Molecular Formula: C14H10ClNOS, Molecular Weight: 275.75. US Biological Life Sciences. |  Worldwide |
| 10-Methyl-7-(2-hydroxy-3-N-Boc-3-phenylpropionyl) Docetaxel | 10-Methyl-7-(2-hydroxy-3-N-Boc-3-phenylpropionyl) Docetaxel is a derivative of baccatin III (B101000), an inhibitor of tubulin disassembly in human cancer cells and also the synthetic precursor of Paclitaxel (P132500). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C58H72N2O18, Molecular Weight: 1085.19. US Biological Life Sciences. | Worldwide |
| 10- (O-2, 2-Dichloroethoxycarbonyl ) 13-(3-O-TES) 7-Epi Docetaxel | 10- (O-2, 2-Dichloroethoxycarbonyl ) 13-(3-O-TES) 7-Epi Docetaxel is an impurity of Docetaxel Hydrate (D494420), a semisynthetic derivative of Paclitaxel(P132500), which is an antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. An antine oplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C52H69Cl2NO16Si, Molecular Weight: 1063.08999999999. US Biological Life Sciences. | Worldwide |
| 10-O-2,2-Dichloroethoxycarbonyl Docetaxel | 10-O-2,2-Dichloroethoxycarbonyl Docetaxel is an impurity of Docetaxel (D494420); an antineoplastic and antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. Group: Biochemicals. Grades: Highly Purified. CAS No. 158810-73-2. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C46H55Cl2NO16. US Biological Life Sciences. | Worldwide |
| 10-O-[(2R,3S)-3-(Benzoylamino)-2-hydroxy-3-phenylpropanoyl]-10-O-deacetylpaclitaxel | 10-O-[(2R,3S)-3-(Benzoylamino)-2-hydroxy-3-phenylpropanoyl]-10-O-deacetylpaclitaxel is an impurity in the synthesis of Paclitaxel (P132500), an antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C61H62N2O16. US Biological Life Sciences. | Worldwide |
| 1,1-Diethoxy-2-methyl-2-propanol | 1,1-Diethoxy-2-methyl-2-propanol is an intermediate in the synthesis of metabolites of docetaxel (D494420), an antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. Group: Biochemicals. Grades: Highly Purified. CAS No. 108994-55-4. Pack Sizes: 100mg, 250mg. Molecular Formula: C8H18O3. US Biological Life Sciences. | Worldwide |
| 1, 2, 3, 4-Tetra hydro-N- hydroxy-2- [ (1- methyl -1H-pyrrol-2-yl ) carbonyl ] -6-isoquinolinecarboxamid e | HDAC6 Inhibitor is a potent and selective inhibitor of HDAC6 that poorly blocks other HDAC enzymes. HDAC6 is a predominantly cytoplasmic enzyme that targets α-tubulin, cortactin, and heat shock protein 90, as well as other substrates. Group: Biochemicals. Grades: Highly Purified. CAS No. 1259296-46-2. Pack Sizes: 500ug, 1mg. Molecular Formula: C16H17N3O3, Molecular Weight: 299.32. US Biological Life Sciences. | Worldwide |
| 1-Bis(4-fluorophenyl)methyl Piperazine | 1-Bis(4-fluorophenyl)methyl Piperazine (Flumazenil EP Impurity A) is a chemical reagent used in the synthesis of novel tubulin polymerization inhibitors. Also used in the synthesis of novel benzhydrylpiperazine carboxamide derivatives. Impurity of F455200. Group: Biochemicals. Grades: Highly Purified. CAS No. 27469-60-9. Pack Sizes: 1g, 10 g. Molecular Formula: C17H18F2N2. US Biological Life Sciences. | Worldwide |
| 1-Bis(4-fluorophenyl)methyl Piperazine-d8 | 1-Bis(4-fluorophenyl)methyl Piperzaine-d8 is a labelled analogue of 1-Bis(4-fluorophenyl)methyl Piperzaine (B434875), which is a chemical reagent used in the synthesis of novel tubulin polymerization inhibitors. Also used in the synthesis of novel benzhydrylpiperazine carboxamide derivatives. Impurity of F455200. It is also an intermediate in synthesizing Flunarizine-d8 Dihydrochloride (F455202), which is a calcium channel blocker; fluorinated derivative of Cinnarizine. Vasodilator (cerebral and peripheral). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C17H10D8F2N2. US Biological Life Sciences. | Worldwide |
| 1-Demethylcolchicine | 1-Demethylcolchicine is a derivative of Colchicine (C640000) an antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway. Group: Biochemicals. Grades: Highly Purified. CAS No. 3464-68-4. Pack Sizes: 10mg, 50mg. Molecular Formula: C21H23NO6, Molecular Weight: 385.41. US Biological Life Sciences. | Worldwide |
| 1-Naphthohydroxamic acid | 1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC 50 of 14 μM. 1-Naphthohydroxamic acid is more selectively for HDAC8 than class I HDAC1 and class II HDAC6 (IC 50 >100 μM). 1-Naphthohydroxamic acid does not increase global histone H4 acetylation and also does not reduce total intracellular HDAC activity [1] [2].1-Naphthohydroxamic acid can induce tubulin acetylation [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 6953-61-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-130538. |  |
| 1-Naphthohydroxamic acid | 1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC50 of 14 μM. 1-Naphthohydroxamic acid is more selectively for HDAC8 than class I HDAC1 and class II HDAC6 (IC50 >100 μM). 1-Naphthohydroxamic acid does not increase global histone H4 acetylation and also does not reduce total intracellular HDAC activity.1-Naphthohydroxamic acid can induce tubulin acetylation. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 6953-61-3. Molecular formula: C11H9NO2. Mole weight: 187.19. Purity: >98.0%(T). Product ID: ACM6953613. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 2,2,3-Tribromopropanal | 2,2,3-Tribromopropanal is a versatile reagent that was used for the first time in the 1950s. It is used as a reagent in the Skraup-type synthesis of 3-bromoquinolin-6-ols. 2,2,3-Tribromopropanal is also used in the preparation of quinolinyloxyacetamide s, a novel class of tubulin polymerization inhibitors with fungicidal activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 26944-17-2. Pack Sizes: 1g, 5g. Molecular Formula: C3H3Br3O, Molecular Weight: 294.77. US Biological Life Sciences. | Worldwide |
| 2,2-Dichloroethanol + 2,2-Dichloroethyl (Trichloromethyl) Carbonate + 2,2-Dichloroethyl Carbonochloridate (Mixture) | 2,2-Dichloroethanol + 2,2-Dichloroethyl (Trichloromethyl) Carbonate + 2,2-Dichloroethyl Carbonochloridate (Mixture) is an intermediate in the synthesis of 10-O-2,2-Dichloroethoxycarbonyl Docetaxel (D434415). 10-O-2,2-Dichloroethoxycarbonyl Docetaxel is an impurity of Docetaxel (D494420); an anti-neoplastic and anti-mitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500mg, 1g. Molecular Formula: C2H4Cl2O + C4H3Cl5O3 + C3H3Cl3O2, Molecular Weight: 114.96276331774. US Biological Life Sciences. | Worldwide |
| 2,4,5-Trimethoxybenzaldehyde | 2,4,5-Trimethoxybenzaldehyde is used in the synthesis of stilbene and hydrostibene derivatives as potential anticancer agents, inhibiting tubulin. Also used in the synthesis of HIV-RT inhibitors. Group: Biochemicals. Alternative Names: 2, 4, 5-Trimethoxybenzalde hyde; 2, 4, 5-Trimethoxylbenzalde hyde; 3, 4, 6-Trimethoxybenzalde hyde; Asaraldehyde; Asaronaldehyde; Asarylaldehyde; Gazarin; NSC 89299. Grades: Highly Purified. CAS No. 4460-86-0. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| 2,7-Bis-O-(Triethylsilyl) 10-Desacetyl Paclitaxel | Protected Paclitaxel. An antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Group: Biochemicals. Alternative Names: (αR, βS)-(2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-6, 11-dihydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-benzenepropanoic Acid β-(Benzoylamino)-α-[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester. Grades: Highly Purified. CAS No. 155556-72-2. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 2-Amino-4-chloro-5-fluorobenzoic acid | 2-Amino-4-chloro-5-fluorobenzoic acid is used to synthesize 2-styrylquinazolin-4(3H)-ones, a new class of antimitotic anticancer agents which inhibit tubulin polymerization. Group: Biochemicals. Grades: Highly Purified. CAS No. 108288-16-0. Pack Sizes: 100mg, 1g. Molecular Formula: C7H5ClFNO2, Molecular Weight: 189.57. US Biological Life Sciences. | Worldwide |
| 2-Azetidinone | 2-Azetidinone are β-lactams which maintain potential for antibiotic activity. Potential to act as tubulin polymerization inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 930-21-2. Pack Sizes: 100mg, 250mg. Molecular Formula: C3H5NO, Molecular Weight: 71.08. US Biological Life Sciences. | Worldwide |
| 2-Fluoro-1,4-dimethoxybenzene | 2-Fluoro-1,4-dimethoxybenzene is used as a reagent to synthesize fluoro analogues of Phenstatin, a tubulin polymerization inhibitor that has potential use as an anticancer agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 82830-49-7. Pack Sizes: 2.5g, 10g. Molecular Formula: C8H9FO2, Molecular Weight: 156.15. US Biological Life Sciences. | Worldwide |
| 2-Formyl-1,1'-biphenyl | 2-Formyl-1,1'-biphenyl is a reactant used in the preparation of imidazoquinoline derivatives, a class of microsomal prostaglandin E2 synthase-1 inhibitors. 2-Formyl-1,1'-biphenyl is also used in the preparation of phenoxybenzylamino carboline derivatives as potential antitumor drugs targeting α-tubulin. Group: Biochemicals. Alternative Names: 2-Formylbiphenyl; 2-Phenylbenzaldehyde; 2-Biphenylcarboxalde hyde; [1,1'-Biphenyl]-2-carboxaldehyde. Grades: Highly Purified. CAS No. 1203-68-5. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 2-Formyl-1,1'-biphenyl-13C6 | 2-Formyl-1,1'-biphenyl-13C6 is a reactant used in the preparation of labelled imidazoquinoline derivatives, a class of microsomal prostaglandin E2 synthase-1 inhibitors. 2-Formyl-1,1'-biphenyl is also used in the preparation of phenoxybenzylamino carboline derivatives as potential antitumor drugs targeting α-tubulin. Group: Biochemicals. Alternative Names: 2-Formylbiphenyl-13C6; 2-Phenylbenzaldehyde-13C6; 2-Biphenylcarboxaldehyde-13C6; [1,1'-Biphenyl]-2-carboxaldehyde-13C6. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 2-Methoxy 17 β-Estradiol-16,16,17-d3 | A natural metabolite of 17 β-Estradiol which is devoid of estrogenic activity. Inhibits cell proliferation and angiogenesis. Binds to the colchicine binding site of tubulin, and has been suggested to function as a natural regulator of microtubule assembly and function. Group: Biochemicals. Alternative Names: (17 β)-2-Methoxy-estra-1,3,5(10)-triene-3,17-diol-16,16,17-d3; 2-Hydroxyestradiol-16,16,17-d3 2-Methyl Ether; 2-Methoxyestra-1,3,5(10)-triene-3,17-diol-16,16,17-d3; NSC 659853-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 2-Methoxy-d3 17 β-Estradiol | A natural metabolite of 17 β-Estradiol which is devoid of estrogenic activity. Inhibits cell proliferation and angiogenesis. Binds to the colchicine binding site of tubulin, and has been suggested to function as a natural regulator of microtubule assembly and function. Group: Biochemicals. Alternative Names: (17 β)-2-Methoxy-d3-estra-1,3,5(10)-triene-3,17-diol; 2-Hydroxyestradiol 2-Methyl-d3 Ether; 2-Methoxy-d3-estra-1,3,5(10)-triene-3,17 β-diol; 2-Methoxy-d3-estradiol; NSC 659853-d3; Panzem-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 2-methoxyestradiol | 2-methoxyestradiol, also known as 2-ME, is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing endothelial cell proliferation and inducing endothelial cell apoptosis. This agent also inhibits tumor cell growth by binding to tubulin, resulting in antimitotic activity, and by inducing caspase activation, resulting in cell cycle arrest in the G2 phase, DNA fragmentation, and apoptosis. Uses: Antineoplastic agents. Synonyms: 2-ME; 2-Methoxy Estradiol. US brand name: Panzem. Abbreviation: 2ME2. Chemical structure name: (17beta)-2-Methoxyestra-1,3,5(10)-triene-3,17-diol. Grades: 0.98. CAS No. 362-07-2. Molecular formula: C19H26O3. Mole weight: 302.414. | |
| 2-Methoxyestradiol | Apoptotic, antiproliferative and antiangiogenic agent, in vitro and in vivo; acts via an estrogen receptor-independent mechanism. Induces p53-induced apoptosis via two pathways: activation of p38 and NF-κB; and activation of JNK and AP-1 leading to Bcl-2 phosphorylation. Also upregulates death receptor 5 and binds to tubulin, inhibiting its assembly. Group: Biochemicals. Grades: Highly Purified. CAS No. 362-07-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| 2-m-Hydroxy(benzoyl) Paclitaxel | 2-m-Hydroxy Paclitaxel is a metabolite of Paclitaxel (P132500), an antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. Group: Biochemicals. Grades: Highly Purified. CAS No. 132160-31-7. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C47H51NO15, Molecular Weight: 869.91. US Biological Life Sciences. | Worldwide |
| 2-Nitro-3-pyridinol | 2-Nitro-3-pyridinol may be used in the synthesis of novel sulfonates that are potent inhibitors of cell proliferation and tubulin polymerization. It may also be used to prepare (aminoaryl) (benzyloxy)pyridines as potential antitumor agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 15128-82-2. Pack Sizes: 5g, 25g. Molecular Formula: C5H4N2O3. US Biological Life Sciences. | Worldwide |
| 2'-O- (tert-Butyldimethylsilyl) paclitaxel 7-O-triflate | 2'-O- (tert-Butyldimethylsilyl) paclitaxel 7-O-triflate is an intermediate in the synthesis of 6α-Hydroxy Paclitaxel (H948890), the major human metabolite of Paclitaxel (P132500), an antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. Group: Biochemicals. Grades: Highly Purified. CAS No. 165065-01-0. Pack Sizes: 5mg, 50mg. Molecular Formula: C54H64F3NO16SSi, Molecular Weight: 1100.23. US Biological Life Sciences. | Worldwide |
| 2-Oxo Docetaxel | 2-Oxo Docetaxel is an impurity of Docetaxel (D494420), a semisynthetic derivative of Paclitaxel(P132500), an antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. An antine oplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C43H51NO14, Molecular Weight: 805.86. US Biological Life Sciences. | Worldwide |
| (2'R)-N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine | (2'R)-N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine is an epimer of N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine (D199035), which is an active metabolite of Maytansine (M197940), inhibits in vitro polymerization of tubulin and is used in the treatment of advanced breast cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 936481-23-1. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C36H50ClN3O10S. US Biological Life Sciences. | Worldwide |
| (2S, 3R)-Cabazitaxel | (2S, 3R)-Cabazitaxel is a stereoisomer of Cabazitaxel (C046500), a novel tubulin binding taxane, that acts as a second-line treatment for those with castration-resistant prostate cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 1714967-27-7. Pack Sizes: 1mg, 10mg. Molecular Formula: C45H57NO14, Molecular Weight: 835.93. US Biological Life Sciences. | Worldwide |
| (2S, 3R)-Cabazitaxel-D6 | (2S, 3R)-Cabazitaxel-D3 is a labelled analogue of (2S, 3R)-Cabazitaxel (C046505). (2S, 3R)-Cabazitaxel (C046505) is a stereoisomer of Cabazitaxel (C046500), a novel tubulin binding taxane, that acts as a second-line treatment for those with castration-resistant prostate cancer. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C45H51D6NO14, Molecular Weight: 841.97. US Biological Life Sciences. | Worldwide |
| 3-Amino-4-methoxybenzoic Acid | 3-Amino-4-methoxybenzoic Acid is a general reactant/reagent used in the synthesis of VEGFR-2 inhibitors. Also used in the preparation of dihydroisoquinoline compounds as tubulin polymerization inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 2840-26-8. Pack Sizes: 5g, 10g. Molecular Formula: C8H9NO3, Molecular Weight: 167.16. US Biological Life Sciences. | Worldwide |
| 3-Bromo-4-methoxyaniline | 3-Bromo-4-methoxyaniline is an intermediate used to prepare triazole analogs of combretastatin A-4 as cytotoxic agents and inhibitors of tubulin. It is also used in the synthesis of (1, 2, 4-oxadiazolyl) biphenylcarbonyltetra hydrospiro [furo] indolepiperidine (SB-224289) as selective 5-HT1B receptor inverse agonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 19056-41-8. Pack Sizes: 500mg, 1g. Molecular Formula: C7H8BrNO, Molecular Weight: 202.05. US Biological Life Sciences. | Worldwide |
| 3-Hydroxy-2-nitropyridine | 3-Hydroxy-2-nitropyridine. Uses: 3-hydroxy-2-nitropyridine may be used in the synthesis of novel sulfonates that are potent inhibitors of cell proliferation and tubulin polymerization. Additional or Alternative Names: 3-pyridinol, 2-nitro- 2-Nitro-3-pyridinol. Product Category: Solvents. CAS No. 15128-82-2. Molecular formula: C5H4N2O3. Mole weight: 140.1. IUPACName: 2-nitropyridin-3-ol. Canonical SMILES: OC1=CC=CN=C1[N+]([O-])=O. Density: 1.5±0.1 g/cm3. ECNumber: 239-191-2. Product ID: ACM15128822. Alfa Chemistry ISO 9001:2015 Certified. | |
| 5(6)-Carboxyfluorescein N-hydroxysuccinimide ester | 5(6)-Carboxyfluorescein N-hydroxysuccinimide ester is an amine-reactive fluorescent probe useful for preparation of tubulin derivatives. Synonyms: 5(6)-FAM SE. CAS No. 117548-22-8. Molecular formula: C25H15NO9. Mole weight: 473.40. | |
| 7-Acetyl Paclitaxel | Biologically active Paclitaxel derivative that interacts with tubulin assemblies in the brain. Group: Biochemicals. Alternative Names: 7-Acetyltaxol; (αR, βS)- β-(Benzoylamino)-α-hydroxy-benzenepropanoic Acid (2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS)-4, 6, 12b-Tris(acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-11-hydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-9-yl Ester. Grades: Highly Purified. CAS No. 92950-39-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 7-O-(Triethylsilyl)-2-O-tert-butyl(dimethyl)silyl Paclitaxel | Protected Paclitaxel. An antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. Group: Biochemicals. Alternative Names: (αR, βS)- β - (Benzoylamino) -α -[[ (1, 1-dimethylethyl) dimethylsilyl]oxy]-benzenepropanoic Acid (2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS)-6, 12b-Bis(acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-11-hydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-9-yl Ester. Grades: Highly Purified. CAS No. 156413-61-5. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| ABT-751 | ABT-751 (E7010) is a novel, highly orally bioavailable sulfonamides antimitotic compound and tubulin binder. It prevents tubulin aggregation by binding to the colchicine site on β-tubulin, leading to cell cycle arrest in G2/M phase and inducing apoptosis , thus effectively preventing cell division. ABT-751 induces autophagy by inhibiting the AKT/MTOR signaling pathway. ABT-751 showed significant inhibition against various types of cancer cells, including lung, gastric, colon, and breast cancer [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E7010. CAS No. 141430-65-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13270. | |
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