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| Product | Description | |
|---|---|---|
| tubulin GTPase | An intrinsic activity of α-tubulin involved in tubulin folding, division plane formation in prokaryotic cells and others. Group: Enzymes. Enzyme Commission Number: EC 3.6.5.6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4717; tubulin GTPase; EC 3.6.5.6. Cat No: EXWM-4717. |  |
| Tubulin Inhibitor 6 | Tubulin inhibitor 6 is a tubulin inhibitor and an effective inhibitor of a variety of cancer cell lines. Synonyms: IHAP1; 2-Chloro-10-(4-Methoxybenzoyl)-10H-Phenothiazine; (2-Chloro-10H-Phenothiazin-10-Yl)(4-Methoxyphenyl)Methanone; Oprea1_789892. Grades: 98%. CAS No. 105925-39-1. Molecular formula: C20H14ClNO2S. Mole weight: 367.8. |  |
| tubulin-tyrosine ligase | L-Tyrosine is linked via a peptide bond to the C-terminus of de-tyrosinated α-tubulin (des-Tyrω-α-tubulin). The enzyme is highly specific for α-tubulin and moderately specific for ATP and L-tyrosine. L-Phenylalanine and 3,4-dihydroxy-L-phenylalanine are transferred but with higher Km values. Group: Enzymes. Enzyme Commission Number: EC 6.3.2.25. CAS No. 60321-03-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5743; tubulin-tyrosine ligase; EC 6.3.2.25; 60321-03-1. Cat No: EXWM-5743. | |
| tubulinyl-Tyr carboxypeptidase | Active at neutral pH, from brain. Group: Enzymes. Synonyms: carboxypeptidase-tubulin; soluble carboxypeptidase; tubulin-tyrosine carboxypeptidase; tubulin carboxypeptidase; tubulinyltyrosine carboxypeptidase; tyrosinotubulin carboxypeptidase; tyrosyltubulin carboxypeptidase; TTCPase; brain I carboxypeptidase. Enzyme Commission Number: EC 3.4.17.17. CAS No. 73050-23-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4069; tubulinyl-Tyr carboxypeptidase; EC 3.4.17.17; 73050-23-4; carboxypeptidase-tubulin; soluble carboxypeptidase; tubulin-tyrosine carboxypeptidase; tubulin carboxypeptidase; tubulinyltyrosine carboxypeptidase; tyrosinotubulin carboxypeptidase; tyrosyltubulin carboxypeptidase; TTCPase; brain I carboxypeptidase. Cat No: EXWM-4069. | |
| α-tubulin N-acetyltransferase | The enzyme from Chlamydomonas flagella also acetylates mammalian brain α-tubulin. Group: Enzymes. Synonyms: α-tubulin acetylase; TAT; α-tubulin acetyltransferase; tubulin N-acetyltransferase; acetyl-CoA:α-tubulin-L-lysine N-acetyltransferase; acetyl-CoA:[α-tubulin]-L-lysine 6-N-acetyltransferase. Enzyme Commission Number: EC 2.3.1.108. CAS No. 99889-90-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2046; α-tubulin N-acetyltransferase; EC 2.3.1.108; 99889-90-4; α-tubulin acetylase; TAT; α-tubulin acetyltransferase; tubulin N-acetyltransferase; acetyl-CoA:α-tubulin-L-lysine N-acetyltransferase; acetyl-CoA:[α-tubulin]-L-lysine 6-N-acetyltransferase. Cat No: EXWM-2046. | |
| 10-(Chloroacetyl)-10H-phenothiazine | 10-(Chloroacetyl)-10H-phenothiazine is useful in the synthesis of phenstatin analogues which exhibits anti-proliferative activity and interaction with tubulin. Group: Biochemicals. Grades: Highly Purified. CAS No. 786-50-5. Pack Sizes: 100mg, 500mg. Molecular Formula: C14H10ClNOS, Molecular Weight: 275.75. US Biological Life Sciences. |  Worldwide |
| 10-Methyl-7-(2-hydroxy-3-N-Boc-3-phenylpropionyl) Docetaxel | 10-Methyl-7-(2-hydroxy-3-N-Boc-3-phenylpropionyl) Docetaxel is a derivative of baccatin III (B101000), an inhibitor of tubulin disassembly in human cancer cells and also the synthetic precursor of Paclitaxel (P132500). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C58H72N2O18, Molecular Weight: 1085.19. US Biological Life Sciences. | Worldwide |
| 10- (O-2, 2-Dichloroethoxycarbonyl ) 13-(3-O-TES) 7-Epi Docetaxel | 10- (O-2, 2-Dichloroethoxycarbonyl ) 13-(3-O-TES) 7-Epi Docetaxel is an impurity of Docetaxel Hydrate (D494420), a semisynthetic derivative of Paclitaxel(P132500), which is an antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. An antine oplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C52H69Cl2NO16Si, Molecular Weight: 1063.08999999999. US Biological Life Sciences. | Worldwide |
| 10-O-2,2-Dichloroethoxycarbonyl Docetaxel | 10-O-2,2-Dichloroethoxycarbonyl Docetaxel is an impurity of Docetaxel (D494420); an antineoplastic and antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. Group: Biochemicals. Grades: Highly Purified. CAS No. 158810-73-2. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C46H55Cl2NO16. US Biological Life Sciences. | Worldwide |
| 10-O-[(2R,3S)-3-(Benzoylamino)-2-hydroxy-3-phenylpropanoyl]-10-O-deacetylpaclitaxel | 10-O-[(2R,3S)-3-(Benzoylamino)-2-hydroxy-3-phenylpropanoyl]-10-O-deacetylpaclitaxel is an impurity in the synthesis of Paclitaxel (P132500), an antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C61H62N2O16. US Biological Life Sciences. | Worldwide |
| 1,1-Diethoxy-2-methyl-2-propanol | 1,1-Diethoxy-2-methyl-2-propanol is an intermediate in the synthesis of metabolites of docetaxel (D494420), an antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. Group: Biochemicals. Grades: Highly Purified. CAS No. 108994-55-4. Pack Sizes: 100mg, 250mg. Molecular Formula: C8H18O3. US Biological Life Sciences. | Worldwide |
| 1, 2, 3, 4-Tetra hydro-N- hydroxy-2- [ (1- methyl -1H-pyrrol-2-yl ) carbonyl ] -6-isoquinolinecarboxamid e | HDAC6 Inhibitor is a potent and selective inhibitor of HDAC6 that poorly blocks other HDAC enzymes. HDAC6 is a predominantly cytoplasmic enzyme that targets α-tubulin, cortactin, and heat shock protein 90, as well as other substrates. Group: Biochemicals. Grades: Highly Purified. CAS No. 1259296-46-2. Pack Sizes: 500ug, 1mg. Molecular Formula: C16H17N3O3, Molecular Weight: 299.32. US Biological Life Sciences. | Worldwide |
| 1-Bis(4-fluorophenyl)methyl Piperazine | 1-Bis(4-fluorophenyl)methyl Piperazine (Flumazenil EP Impurity A) is a chemical reagent used in the synthesis of novel tubulin polymerization inhibitors. Also used in the synthesis of novel benzhydrylpiperazine carboxamide derivatives. Impurity of F455200. Group: Biochemicals. Grades: Highly Purified. CAS No. 27469-60-9. Pack Sizes: 1g, 10 g. Molecular Formula: C17H18F2N2. US Biological Life Sciences. | Worldwide |
| 1-Bis(4-fluorophenyl)methyl Piperazine-d8 | 1-Bis(4-fluorophenyl)methyl Piperzaine-d8 is a labelled analogue of 1-Bis(4-fluorophenyl)methyl Piperzaine (B434875), which is a chemical reagent used in the synthesis of novel tubulin polymerization inhibitors. Also used in the synthesis of novel benzhydrylpiperazine carboxamide derivatives. Impurity of F455200. It is also an intermediate in synthesizing Flunarizine-d8 Dihydrochloride (F455202), which is a calcium channel blocker; fluorinated derivative of Cinnarizine. Vasodilator (cerebral and peripheral). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C17H10D8F2N2. US Biological Life Sciences. | Worldwide |
| 1-Demethylcolchicine | 1-Demethylcolchicine is a derivative of Colchicine (C640000) an antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway. Group: Biochemicals. Grades: Highly Purified. CAS No. 3464-68-4. Pack Sizes: 10mg, 50mg. Molecular Formula: C21H23NO6, Molecular Weight: 385.41. US Biological Life Sciences. | Worldwide |
| 1-Naphthohydroxamic acid | 1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC 50 of 14 μM. 1-Naphthohydroxamic acid is more selectively for HDAC8 than class I HDAC1 and class II HDAC6 (IC 50 >100 μM). 1-Naphthohydroxamic acid does not increase global histone H4 acetylation and also does not reduce total intracellular HDAC activity [1] [2].1-Naphthohydroxamic acid can induce tubulin acetylation [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 6953-61-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-130538. |  |
| 1-Naphthohydroxamic acid | 1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC50 of 14 μM. 1-Naphthohydroxamic acid is more selectively for HDAC8 than class I HDAC1 and class II HDAC6 (IC50 >100 μM). 1-Naphthohydroxamic acid does not increase global histone H4 acetylation and also does not reduce total intracellular HDAC activity.1-Naphthohydroxamic acid can induce tubulin acetylation. Group: Inhibitors. CAS No. 6953-61-3. Molecular formula: C11H9NO2. Mole weight: 187.19. Purity: >98.0%(T). Catalog: ACM6953613. |  |
| 2,2,3-Tribromopropanal | 2,2,3-Tribromopropanal is a versatile reagent that was used for the first time in the 1950s. It is used as a reagent in the Skraup-type synthesis of 3-bromoquinolin-6-ols. 2,2,3-Tribromopropanal is also used in the preparation of quinolinyloxyacetamide s, a novel class of tubulin polymerization inhibitors with fungicidal activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 26944-17-2. Pack Sizes: 1g, 5g. Molecular Formula: C3H3Br3O, Molecular Weight: 294.77. US Biological Life Sciences. | Worldwide |
| 2,2-Dichloroethanol + 2,2-Dichloroethyl (Trichloromethyl) Carbonate + 2,2-Dichloroethyl Carbonochloridate (Mixture) | 2,2-Dichloroethanol + 2,2-Dichloroethyl (Trichloromethyl) Carbonate + 2,2-Dichloroethyl Carbonochloridate (Mixture) is an intermediate in the synthesis of 10-O-2,2-Dichloroethoxycarbonyl Docetaxel (D434415). 10-O-2,2-Dichloroethoxycarbonyl Docetaxel is an impurity of Docetaxel (D494420); an anti-neoplastic and anti-mitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500mg, 1g. Molecular Formula: C2H4Cl2O + C4H3Cl5O3 + C3H3Cl3O2, Molecular Weight: 114.96276331774. US Biological Life Sciences. | Worldwide |
| 2,4,5-Trimethoxybenzaldehyde | 2,4,5-Trimethoxybenzaldehyde is used in the synthesis of stilbene and hydrostibene derivatives as potential anticancer agents, inhibiting tubulin. Also used in the synthesis of HIV-RT inhibitors. Group: Biochemicals. Alternative Names: 2, 4, 5-Trimethoxybenzalde hyde; 2, 4, 5-Trimethoxylbenzalde hyde; 3, 4, 6-Trimethoxybenzalde hyde; Asaraldehyde; Asaronaldehyde; Asarylaldehyde; Gazarin; NSC 89299. Grades: Highly Purified. CAS No. 4460-86-0. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| 2,7-Bis-O-(Triethylsilyl) 10-Desacetyl Paclitaxel | Protected Paclitaxel. An antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Group: Biochemicals. Alternative Names: (αR, βS)-(2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-6, 11-dihydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-benzenepropanoic Acid β-(Benzoylamino)-α-[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester. Grades: Highly Purified. CAS No. 155556-72-2. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 2-Amino-4-chloro-5-fluorobenzoic acid | 2-Amino-4-chloro-5-fluorobenzoic acid is used to synthesize 2-styrylquinazolin-4(3H)-ones, a new class of antimitotic anticancer agents which inhibit tubulin polymerization. Group: Biochemicals. Grades: Highly Purified. CAS No. 108288-16-0. Pack Sizes: 100mg, 1g. Molecular Formula: C7H5ClFNO2, Molecular Weight: 189.57. US Biological Life Sciences. | Worldwide |
| 2-Azetidinone | 2-Azetidinone are β-lactams which maintain potential for antibiotic activity. Potential to act as tubulin polymerization inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 930-21-2. Pack Sizes: 100mg, 250mg. Molecular Formula: C3H5NO, Molecular Weight: 71.08. US Biological Life Sciences. | Worldwide |
| 2-Fluoro-1,4-dimethoxybenzene | 2-Fluoro-1,4-dimethoxybenzene is used as a reagent to synthesize fluoro analogues of Phenstatin, a tubulin polymerization inhibitor that has potential use as an anticancer agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 82830-49-7. Pack Sizes: 2.5g, 10g. Molecular Formula: C8H9FO2, Molecular Weight: 156.15. US Biological Life Sciences. | Worldwide |
| 2-Formyl-1,1'-biphenyl | 2-Formyl-1,1'-biphenyl is a reactant used in the preparation of imidazoquinoline derivatives, a class of microsomal prostaglandin E2 synthase-1 inhibitors. 2-Formyl-1,1'-biphenyl is also used in the preparation of phenoxybenzylamino carboline derivatives as potential antitumor drugs targeting α-tubulin. Group: Biochemicals. Alternative Names: 2-Formylbiphenyl; 2-Phenylbenzaldehyde; 2-Biphenylcarboxalde hyde; [1,1'-Biphenyl]-2-carboxaldehyde. Grades: Highly Purified. CAS No. 1203-68-5. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 2-Formyl-1,1'-biphenyl-13C6 | 2-Formyl-1,1'-biphenyl-13C6 is a reactant used in the preparation of labelled imidazoquinoline derivatives, a class of microsomal prostaglandin E2 synthase-1 inhibitors. 2-Formyl-1,1'-biphenyl is also used in the preparation of phenoxybenzylamino carboline derivatives as potential antitumor drugs targeting α-tubulin. Group: Biochemicals. Alternative Names: 2-Formylbiphenyl-13C6; 2-Phenylbenzaldehyde-13C6; 2-Biphenylcarboxaldehyde-13C6; [1,1'-Biphenyl]-2-carboxaldehyde-13C6. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 2-Methoxy 17 β-Estradiol-16,16,17-d3 | A natural metabolite of 17 β-Estradiol which is devoid of estrogenic activity. Inhibits cell proliferation and angiogenesis. Binds to the colchicine binding site of tubulin, and has been suggested to function as a natural regulator of microtubule assembly and function. Group: Biochemicals. Alternative Names: (17 β)-2-Methoxy-estra-1,3,5(10)-triene-3,17-diol-16,16,17-d3; 2-Hydroxyestradiol-16,16,17-d3 2-Methyl Ether; 2-Methoxyestra-1,3,5(10)-triene-3,17-diol-16,16,17-d3; NSC 659853-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 2-Methoxy-d3 17 β-Estradiol | A natural metabolite of 17 β-Estradiol which is devoid of estrogenic activity. Inhibits cell proliferation and angiogenesis. Binds to the colchicine binding site of tubulin, and has been suggested to function as a natural regulator of microtubule assembly and function. Group: Biochemicals. Alternative Names: (17 β)-2-Methoxy-d3-estra-1,3,5(10)-triene-3,17-diol; 2-Hydroxyestradiol 2-Methyl-d3 Ether; 2-Methoxy-d3-estra-1,3,5(10)-triene-3,17 β-diol; 2-Methoxy-d3-estradiol; NSC 659853-d3; Panzem-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 2-methoxyestradiol | 2-methoxyestradiol, also known as 2-ME, is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing endothelial cell proliferation and inducing endothelial cell apoptosis. This agent also inhibits tumor cell growth by binding to tubulin, resulting in antimitotic activity, and by inducing caspase activation, resulting in cell cycle arrest in the G2 phase, DNA fragmentation, and apoptosis. Uses: Antineoplastic agents. Synonyms: 2-ME; 2-Methoxy Estradiol. US brand name: Panzem. Abbreviation: 2ME2. Chemical structure name: (17beta)-2-Methoxyestra-1,3,5(10)-triene-3,17-diol. Grades: 0.98. CAS No. 362-07-2. Molecular formula: C19H26O3. Mole weight: 302.414. | |
| 2-Methoxyestradiol | Apoptotic, antiproliferative and antiangiogenic agent, in vitro and in vivo; acts via an estrogen receptor-independent mechanism. Induces p53-induced apoptosis via two pathways: activation of p38 and NF-κB; and activation of JNK and AP-1 leading to Bcl-2 phosphorylation. Also upregulates death receptor 5 and binds to tubulin, inhibiting its assembly. Group: Biochemicals. Grades: Highly Purified. CAS No. 362-07-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| 2-m-Hydroxy(benzoyl) Paclitaxel | 2-m-Hydroxy Paclitaxel is a metabolite of Paclitaxel (P132500), an antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. Group: Biochemicals. Grades: Highly Purified. CAS No. 132160-31-7. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C47H51NO15, Molecular Weight: 869.91. US Biological Life Sciences. | Worldwide |
| 2-Nitro-3-pyridinol | 2-Nitro-3-pyridinol may be used in the synthesis of novel sulfonates that are potent inhibitors of cell proliferation and tubulin polymerization. It may also be used to prepare (aminoaryl) (benzyloxy)pyridines as potential antitumor agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 15128-82-2. Pack Sizes: 5g, 25g. Molecular Formula: C5H4N2O3. US Biological Life Sciences. | Worldwide |
| 2'-O- (tert-Butyldimethylsilyl) paclitaxel 7-O-triflate | 2'-O- (tert-Butyldimethylsilyl) paclitaxel 7-O-triflate is an intermediate in the synthesis of 6α-Hydroxy Paclitaxel (H948890), the major human metabolite of Paclitaxel (P132500), an antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. Group: Biochemicals. Grades: Highly Purified. CAS No. 165065-01-0. Pack Sizes: 5mg, 50mg. Molecular Formula: C54H64F3NO16SSi, Molecular Weight: 1100.23. US Biological Life Sciences. | Worldwide |
| 2-Oxo Docetaxel | 2-Oxo Docetaxel is an impurity of Docetaxel (D494420), a semisynthetic derivative of Paclitaxel(P132500), an antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. An antine oplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C43H51NO14, Molecular Weight: 805.86. US Biological Life Sciences. | Worldwide |
| (2'R)-N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine | (2'R)-N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine is an epimer of N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine (D199035), which is an active metabolite of Maytansine (M197940), inhibits in vitro polymerization of tubulin and is used in the treatment of advanced breast cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 936481-23-1. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C36H50ClN3O10S. US Biological Life Sciences. | Worldwide |
| (2S, 3R)-Cabazitaxel | (2S, 3R)-Cabazitaxel is a stereoisomer of Cabazitaxel (C046500), a novel tubulin binding taxane, that acts as a second-line treatment for those with castration-resistant prostate cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 1714967-27-7. Pack Sizes: 1mg, 10mg. Molecular Formula: C45H57NO14, Molecular Weight: 835.93. US Biological Life Sciences. | Worldwide |
| (2S, 3R)-Cabazitaxel-D6 | (2S, 3R)-Cabazitaxel-D3 is a labelled analogue of (2S, 3R)-Cabazitaxel (C046505). (2S, 3R)-Cabazitaxel (C046505) is a stereoisomer of Cabazitaxel (C046500), a novel tubulin binding taxane, that acts as a second-line treatment for those with castration-resistant prostate cancer. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C45H51D6NO14, Molecular Weight: 841.97. US Biological Life Sciences. | Worldwide |
| 3-Amino-4-methoxybenzoic Acid | 3-Amino-4-methoxybenzoic Acid is a general reactant/reagent used in the synthesis of VEGFR-2 inhibitors. Also used in the preparation of dihydroisoquinoline compounds as tubulin polymerization inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 2840-26-8. Pack Sizes: 5g, 10g. Molecular Formula: C8H9NO3, Molecular Weight: 167.16. US Biological Life Sciences. | Worldwide |
| 3-Bromo-4-methoxyaniline | 3-Bromo-4-methoxyaniline is an intermediate used to prepare triazole analogs of combretastatin A-4 as cytotoxic agents and inhibitors of tubulin. It is also used in the synthesis of (1, 2, 4-oxadiazolyl) biphenylcarbonyltetra hydrospiro [furo] indolepiperidine (SB-224289) as selective 5-HT1B receptor inverse agonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 19056-41-8. Pack Sizes: 500mg, 1g. Molecular Formula: C7H8BrNO, Molecular Weight: 202.05. US Biological Life Sciences. | Worldwide |
| 3-Hydroxy-2-nitropyridine | 3-Hydroxy-2-nitropyridine may be used in the synthesis of novel sulfonates that are potent inhibitors of cell proliferation and tubulin polymerization. Group: Solvents. Alternative Names: 3-pyridinol, 2-nitro- 2-Nitro-3-pyridinol. CAS No. 15128-82-2. Molecular formula: C5H4N2O3. Mole weight: 140.1. IUPACName: 2-nitropyridin-3-ol. Canonical SMILES: OC1=CC=CN=C1[N+]([O-])=O. Density: 1.5±0.1 g/cm3. ECNumber: 239-191-2. Catalog: ACM15128822. | |
| 5(6)-Carboxyfluorescein N-hydroxysuccinimide ester | 5(6)-Carboxyfluorescein N-hydroxysuccinimide ester is an amine-reactive fluorescent probe useful for preparation of tubulin derivatives. Synonyms: 5(6)-FAM SE. CAS No. 117548-22-8. Molecular formula: C25H15NO9. Mole weight: 473.40. | |
| 7-Acetyl Paclitaxel | Biologically active Paclitaxel derivative that interacts with tubulin assemblies in the brain. Group: Biochemicals. Alternative Names: 7-Acetyltaxol; (αR, βS)- β-(Benzoylamino)-α-hydroxy-benzenepropanoic Acid (2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS)-4, 6, 12b-Tris(acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-11-hydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-9-yl Ester. Grades: Highly Purified. CAS No. 92950-39-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 7-O-(Triethylsilyl)-2-O-tert-butyl(dimethyl)silyl Paclitaxel | Protected Paclitaxel. An antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. Group: Biochemicals. Alternative Names: (αR, βS)- β - (Benzoylamino) -α -[[ (1, 1-dimethylethyl) dimethylsilyl]oxy]-benzenepropanoic Acid (2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS)-6, 12b-Bis(acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-11-hydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-9-yl Ester. Grades: Highly Purified. CAS No. 156413-61-5. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| ABT-751 | ABT-751 (E7010) is a novel, highly orally bioavailable sulfonamides antimitotic compound and tubulin binder. It prevents tubulin aggregation by binding to the colchicine site on β-tubulin, leading to cell cycle arrest in G2/M phase and inducing apoptosis , thus effectively preventing cell division. ABT-751 induces autophagy by inhibiting the AKT/MTOR signaling pathway. ABT-751 showed significant inhibition against various types of cancer cells, including lung, gastric, colon, and breast cancer [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E7010. CAS No. 141430-65-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13270. | |
| ABT 751 | ABT 751, also called E7010, is a novel bioavailable tubulin-binding and antimitotic agent that inhibits microtubule polymerization (in neuroblastoma: IC50 = 0.6-2.6 μM; in non-neuroblastoma cell lines: IC50 = 0.7-4.6 μM). Synonyms: N-[2-(4-hydroxyanilino)pyridin-3-yl]-4-methoxybenzenesulfonamide; E 7010; E-7010; E7010; N-(2-((4-hydroxyphenyl)amino)-3-pyridinyl)-4-methoxybenzenesulfonamide; ABT-751; 141430-65-1; ABT 751; E-7010; ABT751; UNII-WDT5V5OB9F; E 7010; WDT5V5OB9F; CHEMBL20684. CAS No. 141430-65-1. Molecular formula: C18H17N3O4S. Mole weight: 371.41. | |
| AEZS-112 | AEZS-112, also known as ZEN012, is an orally active small mol. anti-cancer drug which inhibits the polymn. of tubulin at low micromolar concns. AEZS 112 dose-dependently increased non-vital hypodiploid cells and the cytotoxic effect was least pronounced in G2 phase of the cell cycle. AEZS 112 showed anti-tumor activity in human ovarian and endometrial cancer cell lines at low micromolar concns., which could not be abrogated by caspase inhibition and is therefore a good candidate for in vivo studies in these tumors. Synonyms: ZEN012; ZEN 012; ZEN-012; AEZS 112; AEZS112. Grades: 98%. CAS No. 1214741-69-1. Molecular formula: C25H23N3O2. Mole weight: 397.47. | |
| ALB-109564 | ALB 109564(a) is a semi-synthetic derivative of the vinka alkaloid vinblastine with potential antineoplastic activity. Tubulin inhibitor ALB 109564(a) binds to tubulin monomers and inhibits microtubule formation, resulting in disruption of mitotic spindle assembly and arrest of tumor cells in the G2/M phase of the cell cycle. Synonyms: ALB-109564; ALB 109564; ALB109564; ALB 109564(a); Vincaleukoblastine, 12'-(methylthio)-, hydrochloride (1:2). CAS No. 854756-74-4. Molecular formula: C47H60N4O9S. Mole weight: 857.07. | |
| ALB 109564(a) dihydrochloride | ALB 109564(a) is a Tubulin inhibitor as a semi-synthetic derivative of the vinka alkaloid originated by AMRI. It can bind to tubulin monomers and inhibit microtubule formation, this leads to the disruption of mitotic spindle assembly and arrest of tumor cells in the G2/M phase of the cell cycle. Phase I clinical trials for Solid tumours is on going. Uses: Solid tumours. Synonyms: ALB-109564 dihydrochloride; ALB 109564 dihydrochloride; ALB109564 dihydrochloride; Vincaleukoblastine 12(methylthio) hydrochloride (1:2);(3aR,3a1R,4R,5S,5aR,10bR)-methyl 4-acetoxy-3a-ethyl-9-((3S,5S,7S,9S)-5-ethyl-5-hydroxy-9-(methoxycarbonyl)-13-(methylthio)-2,4,5,6,7,8,9,10-octahydro-1H-3,7-methano[1]azacycloundecino[5,4-b]indol-9-yl)-5-hydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate. Grades: 98%. CAS No. 1300114-12-8. Molecular formula: C47H60N4O9S. Mole weight: 930.00. | |
| Albendazole | Albendazole (SKF-62979) is an orally active and broad-spectrum parasiticide with high effectiveness and low host toxicity, is used for the research of gastrointestinal parasites in humans and animals. Albendazole induces apoptosis and autophagy in cancer cells. Albendazole also inhibits tubulin polymerization and HIF-1α , VEGF expression, has antioxidant activity, and inhibits the glycolytic process in cancer cells [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKF-62979. CAS No. 54965-21-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0223. | |
| Albendazole oxide | Albendazole Oxide is a tubulin polymerization or assembly inhibitor. It can be used for livestock and poultry nematode disease, tapeworm disease and trematodiasis. Synonyms: Albendazole Impurity B; Ricobendazole; RS 8852; RS-8852; RS8852. Grades: >98%. CAS No. 54029-12-8. Molecular formula: C12H15N3O3S. Mole weight: 281.33. | |
| Albendazole (Standard) | Albendazole (Standard) is the analytical standard of Albendazole. This product is intended for research and analytical applications. Albendazole (SKF-62979) is an orally active and broad-spectrum parasiticide with high effectiveness and low host toxicity, is used for the research of gastrointestinal parasites in humans and animals. Albendazole induces apoptosis and autophagy in cancer cells. Albendazole also inhibits tubulin polymerization and HIF-1α, VEGF expression, has antioxidant activity, and inhibits the glycolytic process in cancer cells [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 54965-21-8. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0223R. | |
| α-Cyclodextrin | α-Cyclodextrin (α-CD) is a soluble fiber derived from corn. α-Cyclodextrin can deplete sphingolipids and phospholipids from cell membranes. α-Cyclodextrin interacts with tubulin. α-Cyclodextrin improves defenses against SARS-CoV-2 infection. α-Cyclodextrin enhances the anticancer efficacy of Crcumin (HY-N0005) against breast, lung and cervical cancer. α-Cyclodextrin has beneficial effects on body weight and blood lipids [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 10016-20-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B1513. | |
| (-)-α-Narcotinediol | (-)-α-Narcotinediol is a Narcotine derivative, a noscapinoid class of microtubule binding compounds that alter microtubule dynamics without affecting tubulin polymer mass. Noscapinoids show great promise as chemotherapeutic agents for the treatment of human cancers. Unlike Narcotine, (-)-α-Narcotinediol deos not inhibit small-intestinal transport in rats. Group: Biochemicals. Alternative Names: [S-(R*,S*)]-3,4-Dimethoxy-α1-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-1,2-benzenedimethanol; α-Narcotinediol (8CI); 1,3-Dioxolo[4,5-g]isoquinoline, 1,2-benzenedimethanol deriv.; (-)-Narcotinediol; NSC 132826; NSC 279531; Narcotinediol. Grades: Highly Purified. CAS No. 23942-99-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Ansamitocin P3 | Ansamitocin P-3 is a metabolite of Ansamitocin which is a new maytansinoid antitumor antibiotic. Fungal metabolite with antineoplastic, antimitotic activity. Binds to tubulin and inhibits vinblastine-induced spiral formation. Group: Biochemicals. Alternative Names: 3-O-De[2-(acetylmethylamino)-1-oxopropyl]-3-O-(1-oxobutyl)-maytansine; 4, 24-Dioxa-9, 22-diazatetracyclo[19. 3. 1. 110, 14. 03, 5]hexacosane, maytansine deriv.; Ansamitocin P 3; Antibiotic C 15003P3; Maytansinol Butyrate. Grades: Purified. CAS No. 66547-09-9. Pack Sizes: 25mg, 50mg, 100mg, 250mg. Molecular Formula: C32H43CIN2O9, Molecular Weight: 635.14. US Biological Life Sciences. | Worldwide |
| Antiproliferative agent-14 | Antiproliferative agent-14 (compound 3b) a potent tubulin polymerization inhibitor, with an IC 50 of 3.41 μM. Antiproliferative agent-14 has excellent antiproliferative activity. Antiproliferative agent-14 possess the ability to arrest cells at G2/M phases of the cell cycle [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1885900-35-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148265. | |
| AR-42 | AR-42 (HDAC-42; OSU-HDAC42) is a potent, orally bioavailable pan- HDAC inhibitor ( IC 50 =16 nM). AR-42 induces growth inhibition, cell-cycle arrest, apoptosis , and activation of caspases-3/7. AR-42 promotes hyperacetylation of H3, H4, and alpha-tubulin, and up-regulation of p21. AR-42 shows cytotoxicity against various human cancer cell lines [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HDAC-42; OSU-HDAC42. CAS No. 935881-37-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13265. | |
| Auristatin E | Auristatin E is a synthetic analog of dolastatin 10. Auristatin E is a highly potent antimitotic agent.Auristatin E inhibits tubulin polymerization. Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity. Uses: Adcs cytotoxin. Synonyms: Auristatin E. Grades: ≥96.0% (HPLC). CAS No. 160800-57-7. Molecular formula: C40H69N5O7. Mole weight: 732.01. | |
| Auristatin F | Auristatin F, a synthetic analog of dolastatin 10, is a cytotoxic tubulin modifier with potent and selective antitumor activity. It is an MMAF analog and cytotoxin in Antibody-drug conjugates. Uses: Adcs cytotoxin. Synonyms: N,N-Dimethyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-L-phenylalanine; L-Valinamide, N,N-dimethyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-; N,N-Dimethyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S)-1-carboxy-2-phenylethyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide. Grades: ≥97% by HPLC. CAS No. 163768-50-1. Molecular formula: C40H67N5O8. Mole weight: 745.99. | |
| BAL-101553·2HCl | BAL-101553 is an orally available, highly water-soluble lysine prodrug of the synthetic small molecule BAL-27862 with potential antitumor activity. Upon administration of BAL101553 and conversion into the active form BAL-27862, this agent binds to tubulin at a site distinct from the vinca-alkaloid-binding site, and prevents tubulin polymerization and destabilizes microtubules, ultimately leading to cell cycle arrest, blockage of cell division and an induction of cell death in cancer cells. Synonyms: Lisavanbulin dihydrochloride; Lisavanbulin HCl; BAL-101553 dihydrochloride; BAL 101553 dihydrochloride; BAL101553 dihydrochloride. Grades: 98%. CAS No. 1387574-54-0. Molecular formula: C26H31Cl2N9O3. Mole weight: 588.49. | |
| BAL27862 | BAL27862 is a novel synthetic potent inhibitor of tubulin polymerization that induces cancer cell death. BAL27862 is a novel microtubule-destabilizing drug that is currently undergoing phase I clinical evaluation as the prodrug BAL101553. Synonyms: Avanbulin; BAL-27862; BAL 27862. Grades: 98%. CAS No. 798577-91-0. Molecular formula: C20H17N7O2. Mole weight: 387.40. | |
| Batabulin | Batabulin (T138067) is an antitumor agent, which binds covalently and selectively to a subset of the β-tubulin isotypes , thereby disrupting microtubule polymerization. Batabulin affects cell morphology and leads to cell-cycle arrest ultimately induces apoptotic cell death [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: T138067. CAS No. 195533-53-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13563. | |
| Batabulin sodium | Batabulin sodium is a synthetic pentafluorophenylsulfonamide with potential antineoplastic activity. T138067 covalently binds to and selectively modifies the beta 1, beta 2, beta 3, and beta 4 isotypes of beta tubulin at a conserved cysteine residue, resulting in disruption of microtubule polymerization, collapse of the cytoskeleton. Synonyms: T138067 sodium; T138067-sodium; T 138067 sodium; T 67; D03059; D 03059; D-03059; T-138067 sodium. CAS No. 195533-53-0. Molecular formula: C13H7F6NO3S. Mole weight: 371.253. | |
| Batabulin sodium | Batabulin sodium (T138067 sodium) is an antitumor agent, which binds covalently and selectively to a subset of the β-tubulin isotypes , thereby disrupting microtubule polymerization. Batabulin sodium affects cell morphology and leads to cell-cycle arrest ultimately induces apoptotic cell death [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: T138067 sodium. CAS No. 195533-98-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13563A. | |
| Belantamab | Belantamab (GSK2857916) is a humanized IgG1 anti-BCMA/TNFRSF17 monoclonal antibody. Belantamab is linked to MMAF (HY-15579) through a non-cleavable ADC linker to synthesize the antibody-active molecule conjugate (ADC) Belantamab mafodotin (HY-P3239). After binding to BCMA on the surface of tumor cells, Belantamab mafodotin enters the cell through receptor-mediated endocytosis. After entering the cell, Belantamab mafodotin releases MMAF, blocks cell division by inhibiting tubulin polymerization, arrests the cell cycle and induces cell apoptosis. Belantamab can be used for the study of multiple myeloma, especially relapsed/refractory multiple myeloma [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GSK2857914. CAS No. 2061894-48-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9980. | |
| β-Lumi (-)-Colchicine | An analog of Colchicine, beta-lumicolchicine, does not bind tubulin or disrupt microtubules. Group: Biochemicals. Alternative Names: N- [ (7S, 7bR, 10aS) -5, 6, 7, 7b, 8, 10a-Hexahydro-1, 2, 3, 9-tetramethoxy-8-oxobenzo [a]cyclopenta [3, 4]cyclobuta [1, 2-c]cyclohepten-7-yl]acetamide; β-Lumicolchicine. Grades: Highly Purified. CAS No. 6901-13-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Bis-ANS dipotassium | Bis-ANS dipotassium is a fluorescent probe of hydrophobic protein. Bis-ANS binds to tubulin with a K d of 2 μM [1]. Bis-ANS dipotassium is a potent biphasic modulator of protein liquid-liquid phase separation ( LLPS ). Bis-ANS dipotassium promotes LLPS at low concentrations but suppresses LLPS at high concentrations [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 65664-81-5. Pack Sizes: 1 mg. Product ID: HY-129811. | |
| BML-278 | BML-278 is a SIRT1 activator ( EC 150 : 1 μM). BML-278 increases H3K9 methylation and inhibits H3K9 acetylation in both the paternal and maternal pronucleus. BML-278 improves early embryonic development. BML-278 arrests the cell cycle at the G1/S phase, and reduces senescence in primary human mesenchymal cells. BML-278 reduces tubulin acetylation in U937 cells. BML-278 also increases mitochondrial density in murine C2C12 myoblasts [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 120533-76-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W025074. | |
| BMS-275183 | BMS-275183 is an oral C-4 methyl carbonate analogue of paclitaxel that has the same mechanism of action, stabilization of tubulin polymerization. BMS-275183 given p.o. was active in a human, hormone-dependent, prostate tumor model, CWR-22, and just as effective as anti-androgen chemotherapy. BMS-275185 is lack of evidence of clinical benefit with the occurrence of two fatal events of neutropenic sepsis. Synonyms: BMS 275183; BMS275183. CAS No. 355113-98-3. Molecular formula: C43H59NO16. Mole weight: 845.94. | |
| BNC-105 | BNC105 is a novel compound being developed by Bionomics as a Vascular Disrupting Agent (VDA) for treatment of cancer. VDAs are drugs that disrupt the blood vessels that nourish tumours. BNC105 acts as a tubulin polymerization inhibitor and displays 80-fold higher potency against endothelial cells than that of CA4P. CA4P is a VDA currently under evaluation in phase III clinical trials. BNC105 is more potent and offers a wider therapeutic window. CA4P produces 90% vascular disruption at its no observed adverse event level (NOAEL), whereas BNC105 causes 95% vascular disruption at 1/8th of its NOAEL. Tissue distribution analysis of BNC105 in tumor-bearing mice showed that while the drug is cleared from all tissues 24 hours after administration, it is still present at high concentrations within the solid tumor mass. Furthermore, BNC105 treatment causes tumor regressions with complete tumor clearance in 20% of treated animals. Group: Inhibitors. Alternative Names: BCN105; BCN-105; BCN 105. CAS No. 945771-74-4. Molecular formula: C20H20O7. Mole weight: 372.37. Appearance: Beige fluffy powder. Purity: >98%. IUPACName: (7-hydroxy-6-methoxy-2-methylbenzofuran-3-yl)(3,4,5-trimethoxyphenyl)methanone. Canonical SMILES: O=C (C1=C (C)OC2=C (O)C (OC)=CC=C12)C3=CC (OC)=C (OC)C (OC)=C3. Catalog: ACM945771744. | |
| BNC-105 | BNC105 is a novel compound being developed by Bionomics as a Vascular Disrupting Agent (VDA) for treatment of cancer. VDAs are drugs that disrupt the blood vessels that nourish tumours. BNC105 acts as a tubulin polymerization inhibitor and displays 80-fold higher potency against endothelial cells than that of CA4P. CA4P is a VDA currently under evaluation in phase III clinical trials. BNC105 is more potent and offers a wider therapeutic window. CA4P produces 90% vascular disruption at its no observed adverse event level (NOAEL), whereas BNC105 causes 95% vascular disruption at 1/8th of its NOAEL. Tissue distribution analysis of BNC105 in tumor-bearing mice showed that while the drug is cleared from all tissues 24 hours after administration, it is still present at high concentrations within the solid tumor mass. Furthermore, BNC105 treatment causes tumor regressions with complete tumor clearance in 20% of treated animals. Synonyms: BCN-105; BCN105; BCN 105. CAS No. 945771-74-4. Molecular formula: C20H20O7. Mole weight: 372.373. | |
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