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25g Pack Size. Group: Analytical Reagents, Biochemicals, Building Blocks, Diagnostic Raw Materials. Formula: C5H4N4O3. CAS No. 69-93-2. Prepack ID 18110589-25g. Molecular Weight 168.11. See USA prepack pricing.
Uricacid
Uricacid, scavenger of oxygen radical , is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uricacid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 69-93-2. Pack Sizes: 500 mg; 1 g. Product ID: HY-B2130.
UricAcid (8-Hydroxyxanthine)
UricAcid is a heterocyclcic compound that is created when purine nucleotides are broken down of by the human body. High blood concetration of UricAcid is known as hyperuricemia and is often associated with a wide range of disorders and medical conditions such as gout, diabetes and metabolic syndrome. Uricacid may be a marker of oxidative stress and may have a potential therapeutic role as an antioxidant. Group: Biochemicals. Alternative Names: 8-Hydroxyxanthine; 7,9-Dihydro-1H-Purine-2,6,8(3H)-trione; 1H-Purine-2,6,8-triol; 2,6,8-Trihydroxypurine; 2,6,8-Trioxopurine; 2,6,8-Trioxypurine; Lithic Acid; NSC 3975; Purine-2,6,8(1H,3H,9H)-trione. Grades: Highly Purified. CAS No. 69-93-2. Pack Sizes: 100g, 250g, 500g, 1Kg. Molecular Formula: C?H?N?O?, Molecular Weight: 168.11. US Biological Life Sciences.
Worldwide
Uricacid sodium
Uricacid sodium (Monosodium urate), scavenger of oxygen radical , is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uricacid sodium can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Monosodium urate. CAS No. 1198-77-2. Pack Sizes: 200 mg. Product ID: HY-B2130A.
UricAcid is a heterocyclcic compound that is created when purine nucleotides are broken down of by the human body. High blood concetration of UricAcid is known as hyperuricemia and is often associated with a wide range of disorders and medical conditions such as gout, diabetes and metabolic syndrome. Uricacid may be a marker of oxidative stress and may have a potential therapeutic role as an antioxidant. Group: Biochemicals. Alternative Names: 7,9-Dihydro-1H-Purine-2,6,8(3H)-trione; 1H-Purine-2,6,8-triol; 2,6,8-Trihydroxypurine; 2,6,8-Trioxopurine; 2,6,8-Trioxypurine; Lithic Acid; NSC 3975; Purine-2,6,8(1H,3H,9H)-trione. Grades: Purified. CAS No. 1198-77-2. Pack Sizes: 5g, 25g. US Biological Life Sciences.
UricAcid is a heterocyclcic compound that is created when purine nucleotides are broken down of by the human body. High blood concetration of UricAcid is known as hyperuricemia and is often associated with a wide range of disorders and medical conditions such as gout, diabetes and metabolic syndrome. Uricacid may be a marker of oxidative stress and may have a potential therapeutic role as an antioxidant. Group: Biochemicals. Alternative Names: 7,9-Dihydro-1H-Purine-2,6,8(3H)-trione; 1H-Purine-2,6,8-triol; 2,6,8-Trihydroxypurine; 2,6,8-Trioxopurine; 2,6,8-Trioxypurine; Lithic Acid; NSC 3975; Purine-2,6,8(1H,3H,9H)-trione. Grades: Purified. CAS No. 1198-77-2. Pack Sizes: 1mg, 5mg, 25mg. US Biological Life Sciences.
Worldwide
Uricacid (Standard)
Uricacid (Standard) is the analytical standard of Uricacid. This product is intended for research and analytical applications. Uricacid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uricacid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 69-93-2. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B2130R.
1,3,7-TrimethyluricAcid
1,3,7-TrimethyluricAcid is a caffeine derivative, and a methyl derivative of uricacid. Detected as a urine marker of caffeine consumption. Group: Biochemicals. Grades: Highly Purified. CAS No. 5415-44-1. Pack Sizes: 25mg, 50mg. Molecular Formula: C8H10N4O3. US Biological Life Sciences.
Worldwide
1,3,7-TrimethyluricAcid-d9
1,3,7-TrimethyluricAcid-d9 is an isotope labelled analog of 1,3,7-TrimethyluricAcid. 1,3,7-TrimethyluricAcid is a caffeine derivative, and a methyl derivative of uricacid. Detected as a urine marker of caffeine consumption. Group: Biochemicals. Grades: Highly Purified. CAS No. 117490-42-3. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C8HD9N4O3, Molecular Weight: 219.25. US Biological Life Sciences.
Worldwide
1,3-DimethyluricAcid
1,3-DimethyluricAcid. Group: Biochemicals. Alternative Names: 7,9-Dihydro-1,3-dimethyl-1H-purine-2,6,8(3H)-trione; 1,3-Dimethyl UricAcid. Grades: Highly Purified. CAS No. 944-73-0. Pack Sizes: 250mg. Molecular Formula: C7H8N4O3, Molecular Weight: 196.16. US Biological Life Sciences.
3-MethyluricAcid is a methylated derivative of uricacid that inhibits peroxynitrite-mediated oxidation, which has potential therapeutic application in the treatment of multiple sclerosis. 3-MethyluricAcid is also a known metabolite of Caffeine. Group: Biochemicals. Alternative Names: N3-MethyluricAcid; 7,9-Dihydro-3-methyl-1H-purine-2,6,8(3H)-trione. Grades: Highly Purified. CAS No. 605-99-2. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
7-Methyl-3-(trideuteromethyl)uricAcid
7-Methyl-3-(trideuteromethyl)uricAcid. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
ThiouricAcid-13C3 Sodium Salt Dihydrate
A labeled metabolite of Azathioprine. Group: Biochemicals. Alternative Names: 7,9-Dihydro-6-thioxo-1H-purine-2,8(3H,6H)-dione-13C3 Sodium Salt Dihydrate; 6-Thio-uricAcid-13C3 Sodium Dihydrate; 2,8-Dihydroxy-6-mercaptopurine-13C3 Sodium Dihydrate; 6-ThiouricAcid-13C3 Sodium Dihydrate; NSC 46380-13C3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
2-[3-Cyano-4-(3-hydroxy-2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid Ethyl Ester is an intermediate in synthesizing Febuxostat 67M-4 (F229015), which is a derivative compound of Febuxostat 67M-1 (F229005) which is an inhibitor of xanthine oxidase. It reduces uricacid production in the body and also used to reduce the risk of gout or kidney stone formation. Group: Biochemicals. Grades: Highly Purified. CAS No. 1572503-72-0. Pack Sizes: 10mg, 25mg. Molecular Formula: C18H20N2O4S. US Biological Life Sciences.
2-[4-(2-Carboxypropoxy)-3-cyanophenyl]-4-methyl-5-thiazolecarboxylic Acid 5-Ethyl Ester is an intermediate in synthesizing Febuxostat 67M-4 (F229015), which is a derivative compound of Febuxostat 67M-1 (F229005) which is an inhibitor of xanthine oxidase. It reduces uricacid production in the body and also used to reduce the risk of gout or kidney stone formation. Group: Biochemicals. Grades: Highly Purified. CAS No. 1572503-76-4. Pack Sizes: 5mg, 10mg. Molecular Formula: C18H18N2O5S. US Biological Life Sciences.
Worldwide
2-Hydroxy Probenecid
A metabolite of Probenecid. Probenecid is a medication that increases uricacid excretion in the urine. Probenecid can be used in treating gout and hyperuricemia. Synonyms: p-[N-Propyl-N-(2-hydroxypropyl)sulfamoyl]benzoic Acid; dl-4-[N-(2-Hydroxypropyl)-N-propylsulfamoyl]benzoic Acid; 4-[[ (2-Hydroxypropyl) propylamino]sulfonyl]benzoic Acid. Grades: > 95%. CAS No. 28242-02-6. Molecular formula: C13H19NO5S. Mole weight: 301.36.
2-Isopropylpyridin-4-yl-boronic Acid Pinacol Ester is used in preparation of thioacetate compounds as URAT-1 agonists useful in the treatment of diseases assocd. with aberrant levels of uricacid. Group: Biochemicals. Grades: Highly Purified. CAS No. 1352796-58-7. Pack Sizes: 250mg, 2.5g. Molecular Formula: C14H22BNO2, Molecular Weight: 247.14. US Biological Life Sciences.
Worldwide
2-Trifluoromethylphenyl Boronic Acid
2-Trifluoromethylphenyl Boronic Acid is a reagent in the preparation of potent inhibitors of human uricacid transporter 1 (hURAT1). Group: Biochemicals. Grades: Highly Purified. CAS No. 1423-27-4. Pack Sizes: 1g, 5g. Molecular Formula: C7H6BF3O2, Molecular Weight: 189.93. US Biological Life Sciences.
An impurity of benzbromarone and is currently being investigated as a potent human uricacid transporter I inhibitor. Group: Biochemicals. Alternative Names: 3-Bromo-4-hydroxyphenyl 2-ethyl-3-benzofuranyl Ketone,; (3-Bromo-4-hydroxyphenyl)(2-ethylbenzofuran-3-yl)methanone; Bromobenzarone; Benzbromarone Impurity A. Grades: Highly Purified. CAS No. 94729-09-6. Pack Sizes: 100mg, 1g. Molecular Formula: C??H??BrO?, Molecular Weight: 345.19. US Biological Life Sciences.
Worldwide
3-Methyl-2-oxovaleric acid
3-Methyl-2-oxovaleric acid is a degradation product from Isoleucine. 3-Methyl-2-oxovaleric acid is a biomarker of mustard airway diseases (MADs) and uricacid stone [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 1460-34-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-113063.
3-Methyl-2-oxovaleric acid sodium
3-Methyl-2-oxovaleric acid sodium is a degradation product from Isoleucine. 3-Methyl-2-oxovaleric acid sodium is a biomarker of mustard airway diseases (MADs) and uricacid stone [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 3715-31-9. Pack Sizes: 250 mg; 500 mg. Product ID: HY-W017386.
3-Methyl-2-oxovaleric acid (Standard)
3-Methyl-2-oxovaleric acid (Standard) is the analytical standard of 3-Methyl-2-oxovaleric acid (HY-113063). This product is intended for research and analytical applications. 3-Methyl-2-oxovaleric acid is a degradation product from Isoleucine. 3-Methyl-2-oxovaleric acid is a biomarker of mustard airway diseases (MADs) and uricacid stone. Uses: Scientific research. Group: Natural products. CAS No. 1460-34-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113063R.
5-Hydroxyoxindole
5-Hydroxyoxindole is a structural analog of uricacid. 5-Hydroxyoxindole has DPPH radical scavenging activities and lipid peroxidation-inhibitory activities. 5-Hydroxyoxindole can be used for the research of oxidative stress-mediated disorders [1]. Uses: Scientific research. Group: Natural products. CAS No. 3416-18-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W001542.
Allantoin
Vulnerary; debriding agent. Purine metabolite via the uricacid pathway. Group: Biochemicals. Alternative Names: 5-Ureidohydantoin; (2,5-Dioxo-4-imidazolidinyl)urea; Allantol; Cordianine; Glyoxyldiureid; Glyoxyldiureide; Glyoxylic Diureide; NSC 7606; Psoralon; Sebical; Septalan. Grades: Highly Purified. CAS No. 97-59-6. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Allantoin-13C2,15N4
Vulnerary; debriding agent. Purine metabolite via the uricacid pathway. Group: Biochemicals. Alternative Names: 5-Ureidohydantoin-13C2,15N4; (2,5-Dioxo-4-imidazolidinyl)urea-13C2,15N4; Allantol-13C2,15N4; Cordianine-13C2,15N4; Glyoxyldiureid-13C2,15N4; NSC 7606-13C2,15N4; Psoralon-13C2,15N4; Sebical-13C2,15N4; Septalan-13C2,15N4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Allopurinol
Xanthine oxidase inhibitor; decreases uricacid production. Used in treatment of hyperuricemia and chronic gout. Antiurolithic. Group: Biochemicals. Alternative Names: 1,5-Dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one; 4-Hydroxypyrazolo[3,4-d]pyrimidine; 4-Oxopyrazolo[3,4-d]pyrimidine; Adenock; Allopur; Caplenal; Cellidrin; NSC 101655; NSC 1390. Grades: Highly Purified. CAS No. 315-30-0. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Allopurinol-d2
Labeled xanthine oxidase inhibitor; decreases uricacid production. Used in treatment of hyperuricemia and chronic gout. Antiurolithic. Group: Biochemicals. Alternative Names: 1,5-Dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one-d2; 4-Hydroxypyrazolo[3,4-d]pyrimidine-d2; 4-Oxopyrazolo[3,4-d]pyrimidine-d2; Adenock-d2; Allopur-d2; Caplenal-d2; Cellidrin-d2; NSC 101655-d2; NSC 1390-d2. Grades: Highly Purified. CAS No. 916979-34-5. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Allopurinol riboside
Allopurinol riboside is a noteworthy compound, astutely used in research of kidney stones and hyperuricemia, wielding its powers as a potent xanthine oxidase inhibitor. By hindering uricacid compoundion, it proficiently mitigates the jeopardy of crystal deposition. Uses: Antiprotozoal agents. Synonyms: Allopurinol riboside; 16220-07-8; Allopurinol ribonucleoside; Allopurinol-1-ribonucleoside; WZS8452SEC; 4-Hydroxy[3,4-d]pyrazolopyrimidine riboside; CHEMBL1688966; CHEBI:74074; 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,5-dihydro-1-beta-D-ribofuranosyl-; 4-Hydroxy(3,4-d)pyrazolopyrimidine riboside; 1-[(2R,3R,4S,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-5H-PYRAZOLO[3,4-D]PYRIMIDIN-4-ONE; 1-beta-D-Ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidine-4-one; 4H-Pyrazolo(3,4-d)pyrimidin-4-one, 1,5-dihydro-1-.beta.-D-ribofuranosyl-1111. Grades: ≥ 97%. CAS No. 16220-07-8. Molecular formula: C10H12N4O5. Mole weight: 268.23.
Benzarone
Benzarone is an EYA (Eyes Absents), multifunctional protein involved in organogenesis, inhibitor which makes it a potent anticancer agent. EYAs are over expressed in ovarian and breast cancers. As well it is involved in the synthesis of Human UricAcid Transporter 1 inhibitors which may be used to treat kidney diseases. Group: Biochemicals. Alternative Names: (2-Ethyl-3-benzofuranyl) (4-hydroxyphenyl) methanone; 2-Ethyl-3-benzofuranyl p-hydroxyphenyl Ketone; (2-Ethylbenzofuran-3-yl) (4-hydroxyphenyl) methanone; 2-Ethyl-3- (4-hydroxybenzoyl) benzofuran; 2-Ethyl-3- (p-hydroxybenzoyl) benzofuran; 2-Ethyl-3-benzofuranyl p-hydroxyphenyl Ketone; 2-Ethyl-4'-hydroxy-3-benzoylbenzofuran; Benzaron; Fagivil; Fragivil; Fragivix; L 2179-Labaz; L 2197; NSC 82134. Grades: Highly Purified. CAS No. 1477-19-6. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Benzbromarone Impurity A
Benzbromarone Impurity A is an impurity of benzbromarone and is currently being investigated as a potent human uricacid transporter I inhibitor. Synonyms: 3-Bromo-4-hydroxyphenyl 2-ethyl-3-benzofuranyl Ketone,; (3-Bromo-4-hydroxyphenyl)(2-ethylbenzofuran-3-yl)methanone; Bromobenzarone. Grades: > 95%. CAS No. 94729-09-6. Molecular formula: C17H13BrO3. Mole weight: 345.20.
Chemically modified Cucurbita species Ascorbate Oxidase
Oxidoreductase that oxidizes ascorbic acid to dehydroascorbate. Take advantage of the improved stability in liquid reagents. Rely on the proven diagnostic quality of this product. Applications: Use ascorbate oxidase, chemically modified, in a variety of diagnostic tests to eliminate the interference of ascorbic acid, since ascorbic acid interferes with the trinder reaction that is widely used for the colorimetric determination of analytes. it is useful in liquid as well as dry chemistry test, e.g., for the determination of uricacid, lactate or creatinine. Group: Enzymes. Synonyms: ascorbase; ascorbic acid oxidase; ascorbate oxidase; ascorbic oxidase; ascorbate dehydrogenase; L-ascorbic acid oxidase; AAO; L-ascorbate: O2 oxidoreductase; AA oxidase; L-ascorbate oxidase. AAO. Mole weight: Approximately 140 kD. Activity: >180 U/mg lyophilizate (+37°C, L-ascorbate); Specific activity (+37°C): >1,800 U/mg protein. Stability: At -15 to -25°C within specification range for 12 months. Store dry. Keep tightly sealed. Appearance: Turquoise lyophilizate. Source: Cucurbita species. ascorbase; ascorbic acid oxidase; ascorbate oxidase; ascorbic oxidase; ascorbate dehydrogenase; L-ascorbic acid oxidase; AAO; L-ascorbate: O2 oxidoreductase; AA oxidase; EC 1.10.3.3; 9029-44-1; L-ascorbate oxidase. Cat No: DIA-283.
Disodium Bathocuproinedisulfonate [for Determination of Cu in Blood]
Bathocuproinedisulfonic acid disodium salt is used for the determination of iron, copper and uricacid. It is also used as a stain for proteins in polyacrylamide gels. Group: Phenanthroline ligands. Alternative Names: 6733AF; Disodium bathocuproinedisulfonate; FT-0622590; SC-84981; dipotassium 2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline-3,8-disulfonate; GT0734; 52698-84-7; 2,9-Dimethyl-4,7-diphenyl-1,10-phenanthroline disulfonate; Bathocuproinedisulfonic acid sodium salt. CAS No. 52698-84-7. Molecular formula: C26H18N2Na2O6S2. Mole weight: 564.538g/mol. IUPACName: disodium;2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline-3,8-disulfonate. Canonical SMILES: CC1=C (C (=C2C=CC3=C (C (=C (N=C3C2=N1)C)S (=O) (=O)[O-])C4=CC=CC=C4)C5=CC=CC=C5)S (=O) (=O)[O-]. [Na+]. [Na+]. ECNumber: 258-111-7. Catalog: ACM52698847.
Disodium Bathocuproinedisulfonate [for Determination of Cu in Blood]
Disodium Bathocuproinedisulfonate [for Determination of Cu in Blood]. Uses: Bathocuproinedisulfonic acid disodium salt is used for the determination of iron, copper and uricacid. it is also used as a stain for proteins in polyacrylamide gels. Group: Ligands for functional metal complexes. Alternative Names: 6733AF; Disodium bathocuproinedisulfonate; FT-0622590; SC-84981; dipotassium 2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline-3,8-disulfonate; GT0734; 52698-84-7; 2,9-Dimethyl-4,7-diphenyl-1,10-phenanthroline disulfonate; Bathocuproinedisulfonic acid sodium salt. CAS No. 52698-84-7. Product ID: disodium; 2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline-3,8-disulfonate. Molecular formula: 564.538g/mol. Mole weight: C26H18N2Na2O6S2. CC1=C (C (=C2C=CC3=C (C (=C (N=C3C2=N1)C)S (=O) (=O)[O-])C4=CC=CC=C4)C5=CC=CC=C5)S (=O) (=O)[O-]. [Na+]. [Na+]. InChI=1S/C26H20N2O6S2. 2Na/c1-15-25 (35 (29, 30)31)21 (17-9-5-3-6-10-17)19-13-14-20-22 (18-11-7-4-8-12-18)26 (36 (32, 33)34)16 (2)28-24 (20)23 (19)27-15; ; /h3-14H, 1-2H3, (H, 29, 30, 31) (H, 32, 33, 34); ; /q; 2*+1/p-2. RNGKZLRAVYPLJC-UHFFFAOYSA-L.
Etebenecid
Etebenecid, a benzenesulfonic acid derivative, could be used to reduce uricacid levels acting as a uricosuric agent. Uses: Etebenecid could be used to reduce uricacid levels acting as a uricosuric agent. Synonyms: Etebenecidum; Etebenecid; NSC 49467; NSC-49467; NSC49467 Ethebenecide; Urelim; N,N-DIETHYL-4-SULFAMOYLBENZOIC ACID; 4-((diethylamino)sulfonyl)-benzoicaci; p-(diethylsulfamoyl)-benzoicaci; p-(diethylsulfamoyl)benzoicacid; Antidipsin; Etebenecid. Grades: 95%. CAS No. 1213-06-5. Molecular formula: C11H15NO4S. Mole weight: 257.31.
factor-independent urate hydroxylase
This enzyme was previously thought to be a copper protein, but it is now known that the enzymes from soy bean (Glycine max), the mould Aspergillus flavus and Bacillus subtilis contains no copper nor any other transition-metal ion. The 5-hydroxyisourate formed decomposes spontaneously to form allantoin and CO2, although there is an enzyme-catalysed pathway in which EC 3.5.2.17, hydroxyisourate hydrolase, catalyses the first step. The enzyme is different from EC 1.14.13.113 (FAD-dependent urate hydroxylase). Group: Enzymes. Synonyms: uricacid oxidase; uricase; uricase II; urate oxidase. Enzyme Commission Number: EC 1.7.3.3. CAS No. 9002-12-4. UO. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1626; factor-independent urate hydroxylase; EC 1.7.3.3; 9002-12-4; uricacid oxidase; uricase; uricase II; urate oxidase. Cat No: EXWM-1626.
Indacrinone
Indacrinone is a loop diuretic. It can be used as an antihypertensive in patients of gout with hypertension because it decreases reabsorption of uricacid. Uses: Indacrinone can be used as an antihypertensive in patients of gout with hypertension. Synonyms: Indacrinic acid; Indacrynic acid; MK-196; MK 196; MK196; [(6,7-Dichloro-2-methyl-1-oxo-2-phenyl-2,3-dihydro-1H-inden-5-yl) oxy]acetic acid. Grades: 98%. CAS No. 57296-63-6. Molecular formula: C18H14Cl2O4. Mole weight: 365.21.
Lesinurad
Lesinurad(RDEA594), once-daily inhibitor of URAT1, is a transporter in the kidney that regulates uricacid excretion from the body. Synonyms: 2-[[5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid; RDEA 594; Zurampic; [[5-bromo-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid; Lesinida. Grades: >98%. CAS No. 878672-00-5. Molecular formula: C17H14BrN3O2S. Mole weight: 404.28.
Lesinurad Impurity 16
An intermediate of Lesinurad, a urate transporter inhibitor used for the treatment of high blood uricacid levels associated with gout. Synonyms: Methyl 2-(5-broMo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetate. Grades: > 95%. CAS No. 878671-99-9. Molecular formula: C18H16BrN3O2S. Mole weight: 418.32.
Lesinurad sodium
Lesinurad sodium is an once-daily inhibitor of URAT1, which is a transporter in the kidney that regulates uricacid excretion from the body. Synonyms: sodium 2-((5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetate; sodium Lesinurad; RDEA594 sodium; RDEA 594 sodium; RDEA-594 sodium; Zurampic sodium; Acetic acid, 2-((5-bromo-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl)thio)-, sodium salt (1:1). Grades: >98%. CAS No. 1151516-14-1. Molecular formula: C17H13BrN3NaO2S. Mole weight: 426.26.
Native Acremonium sp. Ascorbate Oxidase
In enzymology, a L-ascorbate oxidase (EC 1.10.3.3) is an enzyme that catalyzes the chemical reaction:2 L-ascorbate + O2<-> 2 dehydroascorbate + 2 H2O. Thus, the two substRates of this enzyme are L-ascorbate and O2, whereas its two products are dehydroascorbate and H2O. This enzyme belongs to the family of oxidoreductases, specifically those acting on diphenols and related substances as donor with oxygen as acceptor. This enzyme participates in ascorbate metabolism. It employs one cofactor, copper. Applications: This enzyme is useful for avoidance from interference of ascorbic acid on diagnostic assay such as blood, uricacid, tg, tc and creatinine. Group: Enzymes. Synonyms: ascorbase; ascorbic acid oxidase; ascorbate oxidase; ascorbic oxidase; ascorbate dehydrogenase; L-ascorbic acid oxidase; AAO; L-ascorbate:O2 oxidoreductase;. Enzyme Commission Number: EC 1.10.3.3. CAS No. 9029-44-1. AAO. Mole weight: 80 kDa?gel filtration?. Activity: > 200 U/mg. Appearance: Light blue amorphous powder, lyophilized. Storage: Storage at ?20°C in the presence of a desiccant is recommended. Form: Freeze dried powder. Source: Acremonium sp. ascorbase; ascorbic acid oxidase; ascorbate oxidase; ascorbic oxidase; ascorbate dehydrogenase; L-ascorbic acid oxidase; AAO; L-ascorbate:O2 oxidoreductase; AA oxidase; EC 1.10.3.3; L-ascorbate oxidase. Cat No: NATE-0864.
The enzyme urate oxidase (UO), or uricase or factor-independent urate hydroxylase, absent in humans, catalyzes the oxidation of uricacid to 5-hydroxyisourate: Uricacid + O2 + H2O ? 5-hydroxyisourate + H2O2 ? allantoin + CO2. Urate:oxygen oxidoreductase produced in microorganism has a molecular mass of approximately 34 kda. Group: Enzymes. Synonyms: urate oxidase; uricacid oxidase; uricase; uricase; urate: oxygen oxidoreductase; EC 1.7.3.3; uricase II; UO. Enzyme Commission Number: EC 1.7.3.3. CAS No. 9002-12-4. UO. Activity: 15 U/mg. Appearance: White to off-white powder. Storage: -20°C. Form: Freeze dried powder. Source: Bacillus fastidiosus. urate oxidase; uricacid oxidase; uricase; uricase; urate: oxygen oxidoreductase; EC 1.7.3.3; uricase II; UO. Cat No: DIA-173.
Native Bacillus sp. Uricase
The enzyme urate oxidase (UO), or uricase or factor-independent urate hydroxylase, absent in humans, catalyzes the oxidation of uricacid to 5-hydroxyisourate: Uricacid + O2 + H2O ? 5-hydroxyisourate + H2O2 ? allantoin + CO2. Applications: This enzyme is useful for enzymatic determination of uricacid in clinical analysis. Group: Enzymes. Synonyms: urate oxidase; uricacid oxidase; uricase; uricase; urate: oxygen oxidoreductase; EC 1.7.3.3; uricase II. UO. Mole weight: approx.150,000. Activity: Grade? 1.5U/mg-solid or more. Stability: Stable at -20°C for at least 6 months. Appearance: White amorphous powder, lyophilized. Source: Bacillus sp. urate oxidase; uricacid oxidase; uricase; uricase; urate: oxygen oxidoreductase; EC 1.7.3.3; uricase II. Cat No: DIA-276.
Native Candida sp. Uricase
The enzyme urate oxidase (UO), or uricase or factor-independent urate hydroxylase, absent in humans, catalyzes the oxidation of uricacid to 5-hydroxyisourate: Uricacid + O2 + H2O ? 5-hydroxyisourate + H2O2 ? allantoin + CO2. Applications: This enzyme is useful for enzymatic determination of uricacid in clinical analysis. Group: Enzymes. Synonyms: urate oxidase; uricacid oxidase; uricase; uricase; urate: oxygen oxidoreductase; EC 1.7.3.3; uricase II. Enzyme Commission Number: EC 1.7.3.3. CAS No. 9002-12-4. UO. Mole weight: approx. 120 kDa. Activity: Grade? 4.0U/mg-solid or more (containing approx.20% of stabilizers). Stability: Stable at-20°C for at least one year. Appearance: White amorphous powder, lyophilized. Form: Freeze dried powder. Source: Candida sp. urate oxidase; uricacid oxidase; uricase; uricase; urate: oxygen oxidoreductase; EC 1.7.3.3; uricase II. Cat No: DIA-175.
Native Microorganism Xanthine oxidase
Xanthine oxidase is a form of xanthine oxidoreductase, a type of enzyme that generates reactive oxygen species. These enzymes catalyze the oxidation of hypoxanthine to xanthine and can further catalyze the oxidation of xanthine to uricacid. These enzymes play an important role in the catabolism of purines in some species, including humans. Applications: This enzyme is useful for enzymatic determination of inorganic phosphorus, 5'-nucleotidase and adenosine deaminase when coupled with purine-nucleoside phosphorylase and uricase. Group: Enzymes. Synonyms: EC 1.1.3.22; Xanthine oxidase; XO; XAO. Enzyme Commission Number: EC 1.1.3.22. CAS No. 9054-84-6. XAO. Mole weight: approx. 160 kDa. Activity: Grade? 10U/mg-solid or more. Stability: Stable at-20°C for at least year. Appearance: Reddish brown amorphous powder, lyophilized. Source: Microorganism. EC 1.1.3.22; Xanthine oxidase; XO; XAO. Cat No: DIA-218.
Native Xanthine Dehydrogenase from Bovine milk
Xanthine oxidoreductase (XOR) catalyzes the formation of uricacid from hypoxanthine and xanthine, last two steps of purine catabolism. The mammalian enzyme is synthesized as a xanthine dehydrogenase form (XDH, EC 1.17.1.4), which uses NAD as the electron acceptor, but is converted into an xanthine oxidase form (XO, EC 1.1.3.22) by reversible (through sulfhydryl group oxidation) or irreversible (proteolysis) manner. Since most industrial protocols of XOR purification includes proteolysis step, commercial XOR enzyme is available only as oxidase form unable to use NAD as a an electron acceptor. Group: Enzymes. Synonyms: xanthine dehydrogenase; NAD+-xanthine dehydrogenase; xanthine-NAD+ oxidoreductase; xanthine/NAD+ oxidoreductase; xanthine oxidoreductase; XDH; EC 1.17.1.4. Enzyme Commission Number: EC 1.17.1.4. CAS No. 9054-84-6. XDH. Form: Lyophilized. Source: Bovine milk. Species: Bovine. xanthine dehydrogenase; NAD+-xanthine dehydrogenase; xanthine-NAD+ oxidoreductase; xanthine/NAD+ oxidoreductase; xanthine oxidoreductase; XDH; EC 1.17.1.4. Cat No: NATE-1065.
Oxonic acid potassium salt
Oxonic acid potassium salt is an inhibitor of uricase. It has been used for the inhibition of 5-fluorouracil-induced gastrointestinal toxicity without the loss of its antitumor activity in rats. It has also been used to induce hyperuricemia in rats; as it inhibits uricacid metabolism. Synonyms: potassium;4,6-dioxo-1H-1,3,5-triazine-2-carboxylate. Grades: > 98 %. CAS No. 2207-75-2. Molecular formula: C4H2KN3O4. Mole weight: 195.17.
A uricosuric. Group: Biochemicals. Alternative Names: 4[ (Dipropylamino) sulfonyl]benzoic Acid. Grades: Highly Purified. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
Probenecid Acyl β-D-Glucuronide
A metabolite of Probenecid. Probenecid is a medication that increases uricacid excretion in the urine. Probenecid can be used in treating gout and hyperuricemia. Synonyms: 1-[4-[(Dipropylamino)sulfonyl]benzoate]. Grades: > 95%. CAS No. 34017-15-7. Molecular formula: C19H27NO10S. Mole weight: 461.48.
Probenecid-d14
Uricosuric. Group: Biochemicals. Alternative Names: 4[(Dipropylamino-d14)sulfonyl]benzoic Acid; p-(Dipropylsulfamoyl-d14)benzoic Acid; Apurina-d14; Benecid-d14; Benemid-d14; Benuryl-d14; Probecid-d14. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Rasburicase
Rasburicase is a recombinant urate oxidase and a hyperuricemia inhibitor. Rasburicase converts uricacid into allantoin, making it easier to be cleared by the kidneys and improving the elevated level of uricacid in the blood [1]. Uses: Scientific research. Group: Natural products. CAS No. 134774-45-1. Pack Sizes: 1 mg. Product ID: HY-108844.
Sulfinpyrazone
Sulfinpyrazone is a uricosuric medication used to treat gout. It inhibits uricacid reabsorption in kidney proximal tubules. It can also used to reduce platelet aggregation by inhibiting degranulation of platelets which reduces the release of ADP and thromboxane. It was developed by Novartis and has been listed. Uses: Sulfinpyrazone is a uricosuric medication used to treat gout. Synonyms: G-28315; G28315; G 28315; Anturane; Sulfinpyrazon; Anturan; Diphenylpyrazone; Anturanil; 1,2-Diphenyl-4-(2-(phenylsulfinyl)ethyl)pyrazolidine-3,5-dione; NSC 75925. Grades: 98%. CAS No. 57-96-5. Molecular formula: C23H20N2O3S. Mole weight: 404.48.
Theophylline Impurity 3
An impurity of Dyphylline which is a theophylline derivative used to treat and prevent wheezing and trouble breathing caused by ongoing lung disease. Synonyms: 1,3-Dimethyluricacid; 944-73-0; Oxytheophylline; 1,3-diMethyl-1H-purine-2,6,8(3H,7H,9H)-trione; Ba 2751; 1,3-Dimethylurate; 1,3-dimethyl-7,9-dihydropurine-2,6,8-trione; Uricacid, 1,3-dimethyl-; 1H-Purine-2,6,8(3H)-trione, 7,9-dihydro-1,3-dimethyl-; 7,9-Dihydro-1,3-dimethyl-1H-purine-2,6,8(3H)-trione. Grades: > 95%. CAS No. 944-73-0. Molecular formula: C7H8N4O3. Mole weight: 196.17.
A heterocycloc derivative of phenoxyacetic Acid. Uses as a diuretic, uricosuric, anhtihypertensive. Group: Biochemicals. Alternative Names: [2, 3-Dichloro-4- (2-thienylcarbonyl) phenoxy]acetic Acid, Tienilic Acid, Thienylic Acid, ANP-3624, CE-3624, SKF-62698, Diflurex, Selacryn. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Tienilic Acid
Tienilic acid is a heterocyclic derivative of phenoxyacetic acid that acts as a suicide substrate at the cytochrome P450 enzymes involved in drug metabolism. It is a good mechanism based inhibitor of CYP2C9, and is commonly used as diuretic, uricosuric, antihypertensive. Synonyms: Ticrynafen; Thienylic acid; Selacryn; Diflurex; 2-[2,3-dichloro-4-(thiophene-2-carbonyl)phenoxy]acetic acid. Grades: 99%. CAS No. 40180-04-9. Molecular formula: C13H8Cl2O4S. Mole weight: 331.17.
Tigulixostat
Tigulixostat (LC350189) is an orally active, non-purine selective xanthine oxidase inhibitor. Tigulixostat lowers the production of uricacid. Tigulixostat can be used for gout and hyperuricemia study [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LC350189. CAS No. 1287766-55-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139585.
Ulodesine
Ulodesine, also known as BCX4208, is a purine nucleoside phosphorylase (PNP) inhibitor in development as a once-daily oral, chronic treatment for gout. Ulodesine is currently being developed by Biocryst. Ulodesine acts upstream of xanthine oxidase in the purine metabolism pathway to reduce the production of serum uricacid (sUA). Ulodesine has an IC(50) of 0.5 nM to PNP. BCX-4208 is currently undergoing early clinical investigation in psoriasis and gout. Group: Inhibitors. Alternative Names: BCX4208, BCX 4208, BCX-4208, Ulodesine, DADMe-immucillin H. CAS No. 548486-59-5. Molecular formula: C12H16N4O3. Mole weight: 264.28. Appearance: Solid powder. Purity: >98%. IUPACName: 7-(((3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl)methyl)-3H-pyrrolo[3,2-d]pyrimidin-4(5H)-one. Canonical SMILES: O=C1C (NC=C2CN3C[C@H] (O)[C@@H] (CO)C3)=C2N=CN1. Catalog: ACM548486595.
Ulodesine
Ulodesine, also known as BCX4208, is a purine nucleoside phosphorylase (PNP) inhibitor in development as a once-daily oral, chronic treatment for gout. Ulodesine is currently being developed by Biocryst. Ulodesine acts upstream of xanthine oxidase in the purine metabolism pathway to reduce the production of serum uricacid (sUA). Ulodesine has an IC(50) of 0.5 nM to PNP. BCX-4208 is currently undergoing early clinical investigation in psoriasis and gout. (last update: ). Synonyms: BCX4208; BCX 4208; BCX-4208; DADMe-immucillin H. CAS No. 548486-59-5. Molecular formula: C12H16N4O3. Mole weight: 264.28.
UR 1102
UR 1102 is an inhibitor of the renal urate transporter URAT1. UR 1102 effectively increases the fractional excretion of urinary uricacid, and reduces plasma uricacid. It is promisingly used as a therapeutic for gout or hyperuricemia with an enhanced pharmacokinetic profile. Synonyms: UR 1102; UR1102; UR-1102; (3,5-dibromo-4-hydroxyphenyl)(2,3-dihydro-4H-pyrido[4,3-b]-1,4-oxazin-4-yl)methanone. Grades: 98%. CAS No. 1198153-15-9. Molecular formula: C14H10Br2N2O3. Mole weight: 414.05.
URAT1&XO inhibitor 2
URAT1&XO inhibitor 2 (Compound BDEO) is a dual inhibitor of xanthine oxidase and URAT1 , with IC 50 of 3.3 μM for xanthine oxidase. URAT1&XO inhibitor 2 blocks uptake of uricacid in HEK293 cells expressing URAT1, with a K i value of 0.145 μM. URAT1&XO inhibitor 2 decreases serum urate level and uricacid excretion in hyperuricemic mice. URAT1&XO inhibitor 2 can be used for research of hyperuricemia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1239488-96-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153972.
Urate oxidase, Microorganism
Urate oxidase, Microorganism (Uox), i.e., uricase, is often used in biochemical studies. Urate oxidase is a peroxisomal enzyme that catalyzes the oxidation of uricacid to allantoin in most mammals [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Uox. CAS No. 9002-12-4. Pack Sizes: 1 KU; 5 KU. Product ID: HY-P2921.
Uricase from Candida utilis, Recombinant
The enzyme urate oxidase (UO), or uricase or factor-independent urate hydroxylase, absent in humans, catalyzes the oxidation of uricacid to 5-hydroxyisourate: Uricacid + O2 + H2O ? 5-hydroxyisourate + H2O2 ? allantoin + CO2. Applications: Used in the enzymatic determination of uricacid. Group: Enzymes. Synonyms: urate oxidase; uricacid oxidase; uricase; uricase; urate: oxygen oxidoreductase; EC 1.7.3.3; uricase II. Enzyme Commission Number: EC 1.7.3.3. CAS No. 9002-12-4. UO. Mole weight: 34kDa (SDS-PAGE). Activity: > 6 U/mg. Appearance: White to cream powder. Source: Escherichia coli. Species: Candida utilis. urate oxidase; uricacid oxidase; uricase; uricase; urate: oxygen oxidoreductase; EC 1.7.3.3; uricase II. Cat No: DIA-404.
Uricase from E. coli, Recombinant
The enzyme urate oxidase (UO), or uricase or factor-independent urate hydroxylase, absent in humans, catalyzes the oxidation of uricacid to 5-hydroxyisourate: Uricacid + O2 + H2O ? 5-hydroxyisourate + H2O2 ? allantoin + CO2. Group: Enzymes. Synonyms: urate oxidase; uricacid oxidase; uricase; uricase; urate: oxygen oxidoreductase; EC 1.7.3.3; uricase II. Enzyme Commission Number: EC 1.7.3.3. CAS No. 9002-12-4. UO. Mole weight: ca. 90 kDa. Activity: > 4 U/mg lyophilizate. Stability: Stability (liquid form) stable at 37°C for at least ten days Stability (powder form) stable at 30°C at least three weeks. Appearance: Light brownish lyophilizate. Storage: at -20°C. Source: E. coli. Species: E. coli. urate oxidase; uricacid oxidase; uricase; uricase; urate: oxygen oxidoreductase; EC 1.7.3.3; uricase II. Cat No: DIA-415.
Uricase (Recombinant)
Uricase, Arthrobacter globiformis is a peroxidase enzyme responsible for catalyzing the oxidative reaction of uricacid, converting it into the soluble product allantoin. Uricase, Arthrobacter globiformis can be used for the determination of uricacid levels in serum. The lack of uricase in mammals can lead to kidney diseases caused by the accumulation of uricacid. Uricase, Arthrobacter globiformis can be utilized in research on gout and hyperuricemia [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Uox (Recombinant). CAS No. 9002-12-4. Pack Sizes: 1 KU. Product ID: HY-P2921C.
Uricase, Recombinant
The enzyme urate oxidase (UO), or uricase or factor-independent urate hydroxylase, absent in humans, catalyzes the oxidation of uricacid to 5-hydroxyisourate: Uricacid + O2 + H2O ? 5-hydroxyisourate + H2O2 ? allantoin + CO2. Applications: Uricase cancatalyze the enzymatic oxidation of uricacid to allantoate rapidly, so it is used to detect the amount of uricacid in the serum and urine. Group: Enzymes. Synonyms: urate oxidase; uricacid oxidase; uricase; uricase; urate: oxygen oxidoreductase; EC 1.7.3.3; uricase II. Enzyme Commission Number: EC 1.7.3.3. CAS No. 9002-12-4. Purity: >90% (SDS-PAGE test). UO. Mole weight: About 45kDa (SDS-PAGE detection). Activity: About 10U/mg. Appearance: White powder, lyophilized. Storage: 4°C, store at -20°C for long-term preservation. urate oxidase; uricacid oxidase; uricase; uricase; urate: oxygen oxidoreductase; EC 1.7.3.3; uricase II. Cat No: DIA-294.
Xanthine Oxidase from Arthrobacter sp.
Xanthine oxidase is a form of xanthine oxidoreductase, a type of enzyme that generates reactive oxygen species. These enzymes catalyze the oxidation of hypoxanthine to xanthine and can further catalyze the oxidation of xanthine to uricacid. These enzymes play an important role in the catabolism of purines in some species, including humans. Group: Enzymes. Synonyms: EC 1.17.3.2; Xanthine oxidase; XO; XAO. Enzyme Commission Number: EC 1.17.3.2. CAS No. 9002-17-9. Mole weight: 160 kDa (gel). Activity: >50U/mg protein. Storage: Store at -20°C. Form: Reddish brown amorphous powder, lyophilized. Source: Arthrobacter sp. EC 1.17.3.2; Xanthine oxidase; XO; XAO; XOD. Cat No: NATE-1719.
Xanthine (Standard)
Xanthine (Standard) is the analytical standard of Xanthine. This product is intended for research and analytical applications. Xanthine, a plant alkaloid found in tea, coffee, and cocoa, is a mild stimulant of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation [1] [2] [3]. In Vitro: A number of stimulants are derived from Xanthine including caffeine and theobromine. Xanthine is a product on the pathway of purine degradation. Xanthine is subsequently converted to uricacid by the action of the Xanthine oxidase enzyme. Uses: Scientific research. Group: Natural products. CAS No. 69-89-6. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-W017389R.
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