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| Product | Description | |
|---|---|---|
| Valganciclovir | In cell culture model systems using Caco-2 cells for PEPT1 and SKPT cells for PEPT2, valganciclovir inhibited glycylsarcosine transport mediated by PEPT1 and PEPT2 with K(I) values (inhibition constant) of 1.68+/-0.30 and 0.043+/- 0.005 mM, respectively. The inhibition by valganciclovir was competitive in both cases. 37 patients were enrolled; 19 patients received treatment with VGV and 18 patients received treatment with GCV. The VGV was not inferior in efficacy to GCV as pre-emptive therapy, with rates of viral clearance at 28 days of 89.5% and 83%, respectively (P-value for non-inferiority = 0.030). Toxicities were similar between the 2 arms. No patients developed CMV disease. Patients being treated with an alemtuzumab-containing regimen received prophylaxis with either valaciclovir 500 mg orally daily orvalganciclovir 450 mg orally twice daily. None of the 20 patients randomized to valganciclovir experienced CMV reactivation (P =.004). Synonyms: Valganciclovir. Grades: >98%. CAS No. 175865-60-8. Molecular formula: C14H22N6O5. Mole weight: 354.36. |  |
| Valganciclovir-d5, Hydrochloride | Labelled Valganciclovir, a pro-drug of ganciclovir. Used in treatment of retro-virus. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Valganciclovir-d8 | 2H Labeled Compounds. CAS No. 1132088-63-1. Molecular formula: C14H14D8N6O5. Mole weight: 362.41. Catalog: ACM1132088631. |  |
| Valganciclovir HCl | Valganciclovir hydrochloride hydrate is an antiviral used to treat cytomegalovirus infection. It is the prodrug of ganciclovir, a synthetic analog of 2'-deoxy-guanosine which is phosphorylated to a dGTP analog that competitively inhibits the incorporation of dGTP by viral DNA polymerase. Synonyms: RS 079070-194; Ro 107-9070/194; Valcyte; (S)-Valganciclovir Hydrochloride. Grades: >98%. CAS No. 175865-59-5. Molecular formula: C14H23ClN6O5. Mole weight: 390.82. | |
| Valganciclovir hydrochloride | Valganciclovir hydrochloride is an orally active antiviral agent. Valganciclovir hydrochloride can inhibit the growth of adenoviruses and have a protective effect on immunosuppressed hamsters. Valganciclovir hydrochloride can be used for the research of Cytomegalovirus [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 175865-59-5. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0032A. |  |
| Valganciclovir hydrochloride | Valganciclovir (hydrochloride), the L-valyl ester of ganciclovir, is actually a prodrug for ganciclovir. Valganciclovir is an antiviral medication used to treat cytomegalovirus infections.IC50 Value:Target: CMVin vitro: In cell culture model systems using Caco-2 cells for PEPT1 and SKPT cells for PEPT2, valganciclovir inhibited glycylsarcosine transport mediated by PEPT1 and PEPT2 with K(I) values (inhibition constant) of 1.68+/-0.30 and 0.043+/- 0.005 mM, respectively. The inhibition by valganciclovir was competitive in both cases.in vivo: 37 patients were enrolled; 19 patients received treatment with VGV and 18 patients received treatment with GCV. The VGV was not inferior in efficacy to GCV as pre-emptive therapy, with rates of viral clearance at 28 days of 89.5% and 83%, respectively (P-value for non-inferiority = 0.030). Toxicities were similar between the 2 arms. No patients developed CMV disease. Patients being treated with an alemtuzumab-containing regimen received prophylaxis with either valaciclovir 500 mg orally daily orvalganciclovir 450 mg orally twice daily. None of the 20 patients randomized to valganciclovir experienced CMV reactivation (P =.004). Group: Inhibitors. Alternative Names: VALGANCICLOVIR HYDROCHLORIDE;L-VALINE, 2-[(2-AMINO-1,6-DIHYDRO-6-OXO-9H-PURIN-9-YL)METHOXY]-3-HYDROXYPROPYL ESTER, MONOHYDROCHLORIDE;VALGANCICLOVIR HCL;L-VALINE, 2-[(2-AMINO-1, 6-DIHYDRO-6-OXO-9H-PURIN-9-YL)METHO | |
| Valganciclovir Hydrochloride | A pro-drug of ganciclovir. Used in treatment of retro-virus. Group: Biochemicals. Alternative Names: 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl Ester L-Valine Hydrochloride; RS 079070-194; Ro 107-9070/194; Valcyte; (S)-Valganciclovir Hydrochloride. Grades: Highly Purified. CAS No. 175865-59-5. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C??H??ClN?O?, Molecular Weight: 390.82. US Biological Life Sciences. | Worldwide |
| Valganciclovir hydrochloride impurities | Valganciclovir hydrochloride impurities. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1393911-57-3. Molecular Formula: C14H23ClN6O5. Mole Weight: 390.83. Catalog: APB1393911573. |  |
| Valganciclovir hydrochloride impurities1 | Valganciclovir hydrochloride impurities1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 897937-73-4. Molecular Formula: C19H31N7O6. Mole Weight: 453.5. Catalog: APB897937734. | |
| Valganciclovir Impurity 10 | Valganciclovir Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1654737-32-2. Molecular Formula: C14H21ClN6O4. Mole Weight: 372.81. Catalog: APB1654737322. | |
| Valganciclovir Impurity C | Valganciclovir Impurity C is a derivative of guanine which is on one of the five nucleobases incorporated into biological nucleic acids. Synonyms: 9-Methoxymethyl Guanine; 2-Amino-1,9-dihydro-9-(methoxymethyl)-6H-purin-6-one. Grades: > 95%. CAS No. 1202645-50-8. Molecular formula: C7H9N5O2. Mole weight: 195.18. | |
| Valganciclovir Impurity D | Grades: > 95%. Molecular formula: C14H23N6O5Cl. Mole weight: 390.83. | |
| D-Valganciclovir-d5 Hydrochloride | D-Valganciclovir-d5 Hydrochloride. Group: Biochemicals. Alternative Names: 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl Ester D-Valine-d5 Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C14H18D5ClN6O5, Molecular Weight: 398.85. US Biological Life Sciences. | Worldwide |
| D-Valganciclovir Hydrochloride | D-Valganciclovir Hydrochloride. Group: Biochemicals. Alternative Names: 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl Ester D-Valine Hydrochloride. Grades: Highly Purified. CAS No. 1393911-57-3. Pack Sizes: 10mg. Molecular Formula: C14H23ClN6O5, Molecular Weight: 390.82. US Biological Life Sciences. | Worldwide |
| D-Valganciclovir Hydrochloride | D-Valganciclovir is the D-isomer of Valganciclovir. Synonyms: 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl Ester D-Valine Hydrochloride. Grades: > 95%. CAS No. 1393911-57-3. Molecular formula: C14H23N6O5Cl. Mole weight: 390.83. | |
| N-Carbobenzyloxy-L-valinyl-ganciclovir (CBz-Valganciclovir) | N-Carbobenzyloxy-L-valinyl-ganciclovir (CBz-Valganciclovir). Group: Biochemicals. Alternative Names: CBz-Valganciclovir. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| N-(L-Valyl) Valganciclovir Hydrochloride | N-(L-Valyl) Valganciclovir Hydrochloride is a dipeptide monoester prodrugs of the antiviral drug Ganciclovir. Synonyms: L-Valyl-L-valine 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3- hydroxypropyl Ester Hydrochloride. Grades: > 95%. Molecular formula: C19H32N7O6Cl. Mole weight: 489.96. | |
| N-Methyl Valganciclovir-d5 Hydrochloride | N-Methyl Valganciclovir-d5 Hydrochloride. Group: Biochemicals. Alternative Names: N-Methyl-L-valine 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl Ester-d5 Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C15H20D5ClN6O5, Molecular Weight: 409.88. US Biological Life Sciences. | Worldwide |
| N-Methyl Valganciclovir Hydrochloride | N-Methyl Valganciclovir Hydrochloride. Group: Biochemicals. Alternative Names: N-Methyl-L-valine 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl Ester Hydrochloride. Grades: Highly Purified. CAS No. 1401562-16-0. Pack Sizes: 10mg. Molecular Formula: C15H25ClN6O5, Molecular Weight: 404.85. US Biological Life Sciences. | Worldwide |
| N-Methyl Valganciclovir Hydrochloride (Mixture of Diastereomers) | N-Methyl Valganciclovir Hydrochloride (Mixture of Diastereomers). Uses: For analytical and research use. Group: Impurity standards. Pack Sizes: 10MG. Catalog: APS010635. Format: Neat. Shipping: Room Temperature. | |
| O-Acetyl N-Benzyloxycarbonyl Valganciclovir | O-Acetyl N-Benzyloxycarbonyl Valganciclovir is a protected Valganciclovir. Synonyms: N-[(PhenylMethoxy)carbonyl]-L-valine 3-(Acetyloxy)-2-[(2-aMino-1,6-dihydro-6-oxo-9H-purin-9-yl)Methoxy]propyl Ester. Grades: > 95%. CAS No. 194159-22-3. Molecular formula: C24H30N6O8. Mole weight: 530.54. | |
| O-Acetyl N-Benzyloxycarbonyl Valganciclovir | Protected Valganciclovir, a pro-drug of ganciclovir. Group: Biochemicals. Alternative Names: N-[ (Phenylmethoxy) carbonyl]-L-valine 3-(Acetyloxy)-2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]propyl Ester. Grades: Highly Purified. CAS No. 194159-22-3. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| O-Acetyl N-Benzyloxycarbonyl Valganciclovir-d5 | Protected, labeled Valganciclovir, a pro-drug of ganciclovir. Group: Biochemicals. Alternative Names: N-[ (Phenylmethoxy) carbonyl]-L-valine 3-(Acetyloxy)-2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]propyl Ester-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| O-Acetyl N-cbz valganciclovir | O-Acetyl N-cbz valganciclovir. Group: Biochemicals. Alternative Names: N-[ (Phenylmethoxy) carbonyl]-L-valine 3-(acetyloxy)-2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]propyl ester. Grades: Highly Purified. CAS No. 194159-22-3. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C24H30N6O8. US Biological Life Sciences. | Worldwide |
| S, R-Isovalganciclovir Impurity | S, R-Isovalganciclovir Impurity is an impurity of Valganciclovir. Synonyms: (R,S)-Iso Valganciclovir; (R)-[(S)-3-[(2-Amino-6-oxo-1,6-dihydropurin-9-yl)methoxy)-2-hydroxypropyl)-2,3-dimethylbutanoate. Grades: > 95%. CAS No. 1356932-18-7. Molecular formula: C14H22N6O5. Mole weight: 354.36. | |
| S, S-Isovalganciclovir Impurity | S, S-Isovalganciclovir Impurity is an impurity of Valganciclovir. Synonyms: (S,S)-Iso Valganciclovir Hydrochloride; (2S)-3-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-L-valine 2-Hydroxypropyl Ester Hydrochloride. Grades: > 95%. CAS No. 1401562-13-7. Molecular formula: C14H23N6O5Cl. Mole weight: 390.83. | |
| Ganciclovir Impurity N | Ganciclovir Impurity N is an impurity of Valganciclovir. Synonyms: Ganciclovir mono-N-methyl valinate; 2-(RS)-[(Guanin-9-yl)methoxy]-3-hydroxypropyl N-methyl-L-valinate hydrochloride; N-Methyl-L-valine 2-(2-amino-6-oxo-1,6-dihydropurin-9-ylmethoxy)-3-hydroxypropyl ester monohydrochloride; N-Methylvalganciclovir hydrochlorid. Grades: > 95%. CAS No. 1401562-16-0. Molecular formula: C15H25N6O5Cl. Mole weight: 404.86. | |
| N-Carbobenzyloxy-L-valinyl-ganciclovir | Synonyms: CBz-Valganciclovir; N-[(Phenylmethoxy)carbonyl]-L-valine 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl Ester; 2-(2-Amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-3-hydroxy-1-propyl N-(benzyloxycarbonyl)-L-valinate; Cbz-Valine ganciclovir. Grades: > 95%. CAS No. 194154-40-0. Molecular formula: C22H28N6O7. Mole weight: 488.50. | |
| N-Carbobenzyloxy-L-valinyl-ganciclovir-d5 | N-Carbobenzyloxy-L-valinyl-ganciclovir-d5. Group: Biochemicals. Alternative Names: CBz-Valganciclovir-d5; N-[ (Phenylmethoxy) carbonyl]-L-valine-d5 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl Ester-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| N-Cbz-L-valinyl-ganciclovir | N-Cbz-L-valinyl-ganciclovir. Group: Biochemicals. Alternative Names: Cbz-valganciclovir; N-[ (Phenylmethoxy) carbonyl]-L-valine 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester. Grades: Highly Purified. CAS No. 194154-40-0. Pack Sizes: 10g, 25g, 50g, 100g. Molecular Formula: C22H28N6O7. US Biological Life Sciences. | Worldwide |
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