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Valganciclovirhydrochloride is an orally active antiviral agent. Valganciclovirhydrochloride can inhibit the growth of adenoviruses and have a protective effect on immunosuppressed hamsters. Valganciclovirhydrochloride can be used for the research of Cytomegalovirus [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 175865-59-5. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0032A.
Valganciclovirhydrochloride
Valganciclovir (hydrochloride), the L-valyl ester of ganciclovir, is actually a prodrug for ganciclovir. Valganciclovir is an antiviral medication used to treat cytomegalovirus infections.IC50 Value:Target: CMVin vitro: In cell culture model systems using Caco-2 cells for PEPT1 and SKPT cells for PEPT2, valganciclovir inhibited glycylsarcosine transport mediated by PEPT1 and PEPT2 with K(I) values (inhibition constant) of 1.68+/-0.30 and 0.043+/- 0.005 mM, respectively. The inhibition by valganciclovir was competitive in both cases.in vivo: 37 patients were enrolled; 19 patients received treatment with VGV and 18 patients received treatment with GCV. The VGV was not inferior in efficacy to GCV as pre-emptive therapy, with rates of viral clearance at 28 days of 89.5% and 83%, respectively (P-value for non-inferiority = 0.030). Toxicities were similar between the 2 arms. No patients developed CMV disease. Patients being treated with an alemtuzumab-containing regimen received prophylaxis with either valaciclovir 500 mg orally daily orvalganciclovir 450 mg orally twice daily. None of the 20 patients randomized to valganciclovir experienced CMV reactivation (P =.004). Group: Inhibitors. Alternative Names: VALGANCICLOVIRHYDROCHLORIDE;L-VALINE, 2-[(2-AMINO-1,6-DIHYDRO-6-OXO-9H-PURIN-9-YL)METHOXY]-3-HYDROXYPROPYL ESTER, MONOHYDROCHLORIDE;VALGANCICLOVIR HCL;L-VALINE, 2-[(2-AMINO-1, 6-DIHYDRO-6-OXO-9H-PURIN-9-YL)METHO
ValganciclovirHydrochloride
A pro-drug of ganciclovir. Used in treatment of retro-virus. Group: Biochemicals. Alternative Names: 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl Ester L-Valine Hydrochloride; RS 079070-194; Ro 107-9070/194; Valcyte; (S)-ValganciclovirHydrochloride. Grades: Highly Purified. CAS No. 175865-59-5. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C??H??ClN?O?, Molecular Weight: 390.82. US Biological Life Sciences.
Worldwide
Valganciclovirhydrochloride impurities
Valganciclovirhydrochloride impurities. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1393911-57-3. Molecular Formula: C14H23ClN6O5. Mole Weight: 390.83. Catalog: APB1393911573.
Valganciclovirhydrochloride impurities1
Valganciclovirhydrochloride impurities1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 897937-73-4. Molecular Formula: C19H31N7O6. Mole Weight: 453.5. Catalog: APB897937734.
D-Valganciclovir-d5 Hydrochloride
D-Valganciclovir-d5 Hydrochloride. Group: Biochemicals. Alternative Names: 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl Ester D-Valine-d5 Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C14H18D5ClN6O5, Molecular Weight: 398.85. US Biological Life Sciences.
Worldwide
D-ValganciclovirHydrochloride
D-ValganciclovirHydrochloride. Group: Biochemicals. Alternative Names: 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl Ester D-Valine Hydrochloride. Grades: Highly Purified. CAS No. 1393911-57-3. Pack Sizes: 10mg. Molecular Formula: C14H23ClN6O5, Molecular Weight: 390.82. US Biological Life Sciences.
Worldwide
D-ValganciclovirHydrochloride
D-Valganciclovir is the D-isomer of Valganciclovir. Synonyms: 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl Ester D-Valine Hydrochloride. Grades: > 95%. CAS No. 1393911-57-3. Molecular formula: C14H23N6O5Cl. Mole weight: 390.83.
N-(L-Valyl) ValganciclovirHydrochloride
N-(L-Valyl) ValganciclovirHydrochloride is a dipeptide monoester prodrugs of the antiviral drug Ganciclovir. Synonyms: L-Valyl-L-valine 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3- hydroxypropyl Ester Hydrochloride. Grades: > 95%. Molecular formula: C19H32N7O6Cl. Mole weight: 489.96.
N-Methyl Valganciclovir-d5 Hydrochloride
N-Methyl Valganciclovir-d5 Hydrochloride. Group: Biochemicals. Alternative Names: N-Methyl-L-valine 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl Ester-d5 Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C15H20D5ClN6O5, Molecular Weight: 409.88. US Biological Life Sciences.
Worldwide
N-Methyl ValganciclovirHydrochloride
N-Methyl ValganciclovirHydrochloride. Group: Biochemicals. Alternative Names: N-Methyl-L-valine 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl Ester Hydrochloride. Grades: Highly Purified. CAS No. 1401562-16-0. Pack Sizes: 10mg. Molecular Formula: C15H25ClN6O5, Molecular Weight: 404.85. US Biological Life Sciences.
Worldwide
N-Methyl ValganciclovirHydrochloride (Mixture of Diastereomers)
N-Methyl ValganciclovirHydrochloride (Mixture of Diastereomers). Uses: For analytical and research use. Group: Impurity standards. Pack Sizes: 10MG. Catalog: APS010635. Format: Neat. Shipping: Room Temperature.
Valganciclovir-d5, Hydrochloride
Labelled Valganciclovir, a pro-drug of ganciclovir. Used in treatment of retro-virus. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ganciclovir Impurity N
Ganciclovir Impurity N is an impurity of Valganciclovir. Synonyms: Ganciclovir mono-N-methyl valinate; 2-(RS)-[(Guanin-9-yl)methoxy]-3-hydroxypropyl N-methyl-L-valinate hydrochloride; N-Methyl-L-valine 2-(2-amino-6-oxo-1,6-dihydropurin-9-ylmethoxy)-3-hydroxypropyl ester monohydrochloride; N-Methylvalganciclovir hydrochlorid. Grades: > 95%. CAS No. 1401562-16-0. Molecular formula: C15H25N6O5Cl. Mole weight: 404.86.
S, S-Isovalganciclovir Impurity
S, S-Isovalganciclovir Impurity is an impurity of Valganciclovir. Synonyms: (S,S)-Iso ValganciclovirHydrochloride; (2S)-3-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-L-valine 2-Hydroxypropyl Ester Hydrochloride. Grades: > 95%. CAS No. 1401562-13-7. Molecular formula: C14H23N6O5Cl. Mole weight: 390.83.
Valganciclovir HCl
Valganciclovirhydrochloride hydrate is an antiviral used to treat cytomegalovirus infection. It is the prodrug of ganciclovir, a synthetic analog of 2'-deoxy-guanosine which is phosphorylated to a dGTP analog that competitively inhibits the incorporation of dGTP by viral DNA polymerase. Synonyms: RS 079070-194; Ro 107-9070/194; Valcyte; (S)-ValganciclovirHydrochloride. Grades: >98%. CAS No. 175865-59-5. Molecular formula: C14H23ClN6O5. Mole weight: 390.82.
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