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| Product | Description | |
|---|---|---|
| Valsartan | 1g Pack Size. Group: Bioactive Small Molecules, Chiral Compounds, Organics, Research Organics & Inorganics. Formula: C24H29N5O3. CAS No. 137862-53-4. Prepack ID 18891087-1g. Molecular Weight 435.52. See USA prepack pricing. |  |
| Valsartan | 5g Pack Size. Group: Bioactive Small Molecules, Chiral Compounds, Organics, Research Organics & Inorganics. Formula: C24H29N5O3. CAS No. 137862-53-4. Prepack ID 18891087-5g. Molecular Weight 435.52. See USA prepack pricing. | |
| Valsartan | Valsartan (CGP 48933) is an angiotensin II receptor antagonist and has the potential for high blood pressure and heart failure research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGP 48933. CAS No. 137862-53-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18204. |  |
| Valsartan | Valsartan. Group: Biochemicals. Grades: Purified. CAS No. 137862-53-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Valsartan | Valsartan is a selective angiotensin II receptor antagonist, used to treat high blood pressure and congestive heart failure. Uses: Angiotensin ii type 1 receptor blockers; antihypertensive agents. Synonyms: CGP48933, CGP-48933, CGP 48933, Valsartan, Diovan, Miten, Nisis, Prova, Tareg, Vals, Walsartan. Grade: >98%. CAS No. 137862-53-4. Molecular formula: C24H29N5O3. Mole weight: 435.52. |  |
| Valsartan benzyl ester | Valsartan benzyl ester. Group: Biochemicals. Alternative Names: N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]; (S)-Benzyl 2-(N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoate. Grades: Highly Purified. CAS No. 137863-20-8. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C31H35N5O3. US Biological Life Sciences. | Worldwide |
| Valsartan-d3 (N-(1-Oxopentyl-d3)-N-[[2-(1H-tetrazol-5-yl)[1,1-biphenyl]-4-yl]methyl]-L-valine) | An isotopically labeled version of Valsartan, a nonpeptide angiotensin II AT1-receptor antagonist. Group: Biochemicals. Alternative Names: N-(1-Oxopentyl-d3)-N-[[2-(1H-tetrazol-5-yl)[1,1-biphenyl]-4-yl]methyl]-L-valine. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Valsartan-[d9] | Valsartan-[d9] is the labelled analogue of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Uses: An isotopic labelled form of valsartan, an antagonist of nonpeptide angiotensin ii at1-receptor, is commonly used as an antihypertensive agent and seems to have potential effect in alzheimer's disease. Synonyms: Valsartan D9; N-(1-Oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine-d9. Grade: 98% HPLC. CAS No. 1089736-73-1. Molecular formula: C24H20D9N5O3. Mole weight: 444.57. | |
| Valsartan-d9 (Major) | An isotopically labeled version of Valsartan , a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive. Group: Biochemicals. Alternative Names: N-(1-Oxopentyl)-N-[[2-(1H-tetrazol-5-yl)[1,1-biphenyl]-4-yl]methyl]-L-valine-d9; CGP 48933-d9; Diovan-d9; Nisis-d9; Tareg-d9; Valsartan-d9. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Valsartan (Diovan, N-(1-Oxopentyl)-N-[[2-(1H-tetrazol-5-yl)[1,1-biphenyl]-4-yl]methyl]-L-valine, CGP-48933) | A nonpeptide angiotensin II AT1-receptor antagonist. Group: Biochemicals. Alternative Names: Diovan, N-(1-Oxopentyl)-N-[[2-(1H-tetrazol-5-yl)[1,1-biphenyl]-4-yl]methyl]-L-valine, CGP-48933. Grades: Highly Purified. CAS No. 137862-53-4. Pack Sizes: 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences. | Worldwide |
| Valsartan impurity 16 (sacubitril impurity 1) | Valsartan impurity 16 (sacubitril impurity 1). Uses: For analytical and research use. Group: Impurity standards. CAS No. 102341-56-8. Molecular formula: C23H29NO4. Mole weight: 383.48. Catalog: APB102341568. |  |
| Valsartan Impurity 25 | Valsartan Impurity 25. Uses: For analytical and research use. Group: Impurity standards. CAS No. 133051-88-4. Molecular formula: C33H25BrN4. Mole weight: 557.5. Catalog: APB133051884. | |
| Valsartan Impurity 37 | Valsartan Impurity 37. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1071286-94-6. Molecular formula: C19H20N2O2. Mole weight: 308.38. Catalog: APB1071286946. | |
| Valsartan Impurity 40 (Sacubitril impurity 40) | Valsartan Impurity 40 (Sacubitril impurity 40). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1038924-97-8. Molecular formula: C24H27NO4. Mole weight: 393.48. Catalog: APB1038924978. | |
| Valsartan Impurity 48 (Sacubitril impurity 48) | Valsartan Impurity 48 (Sacubitril impurity 48). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1012341-48-8. Molecular formula: C23H27NO4. Mole weight: 381.46. Catalog: APB1012341488. | |
| Valsartan Impurity49 (Sacubitril impurity 49) | Valsartan Impurity49 (Sacubitril impurity 49). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1012341-50-2. Molecular formula: C23H29NO4. Mole weight: 383.49. Catalog: APB1012341502. | |
| Valsartan Impurity 71 | Valsartan Impurity 71. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1331908-02-1. Molecular formula: C24H26D3N5O3. Mole weight: 438.55. Catalog: APB1331908021. | |
| Valsartan Impurity 78 | Valsartan Impurity 78. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1332623-79-6. Molecular formula: C22H25N5O3. Mole weight: 407.47. Catalog: APB1332623796. | |
| Valsartan Impurity 82 | Valsartan Impurity 82. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1015037-46-3. Molecular formula: C23H27NO4. Mole weight: 381.47. Catalog: APB1015037463. | |
| Valsartan Impurity 8 (Irbesartan Impurity 26) | Valsartan Impurity 8 (Irbesartan Impurity 26). Uses: For analytical and research use. Group: Impurity standards. CAS No. 152708-24-2. Molecular formula: C14H11N7. Mole weight: 277.29. Catalog: APB152708242. | |
| Valsartan Isopropyl Ester | Valsartan Isoporpyl Ester is an impurity of Valsartan (V095750), a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive. Group: Biochemicals. Grades: Highly Purified. CAS No. 1245820-09-0. Pack Sizes: 50mg, 500mg. Molecular Formula: C27H35N5O3, Molecular Weight: 477.6. US Biological Life Sciences. | Worldwide |
| Valsartan methyl ester | An impurity of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Synonyms: Valsartan Methyl Ester; N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-Valine Methyl Ester; N-(1-Oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-Valine Methyl Ester; N-(1-Oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine Methyl Ester. Grade: 98.0%. CAS No. 137863-17-3. Molecular formula: C25H31N5O3. Mole weight: 449.56. | |
| Valsartan methyl ester | Valsartan methyl ester (Compound 3) is a derivative of Valsartan (HY-18204). Valsartan methyl ester is an orally active antagonist for angiotensin II , that inhibits angiotensin II ( IC 50 of 0.06 μM), angiotensin II-induced pressor response in rabbit aorta ( IC 50 of 0.068 μM) and angiotensin II-induced pressor response in the pithed rat model (10% inhibition at 10 mg/kg, p.o.) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGP 48933 methyl ester. CAS No. 137863-17-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W414915. | |
| Valsartan Methyl Ester | Valsartan Methyl Ester. Group: Biochemicals. Alternative Names: N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-Valine Methyl Ester; N-(1-Oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-Valine Methyl Ester; N-(1-Oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine Methyl Ester. Grades: Highly Purified. CAS No. 137863-17-3. Pack Sizes: 50mg. Molecular Formula: C25H31N5O3, Molecular Weight: 449.55. US Biological Life Sciences. | Worldwide |
| Valsartan Methyl Ester-d9 | Valsartan Methyl Ester-d9. Group: Biochemicals. Alternative Names: N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine Methyl Ester-d9; N-(1-Oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-Valine Methyl Ester-d9; N-(1-Oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine Methyl Ester-d9. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C25H22D9N5O3, Molecular Weight: 458.6. US Biological Life Sciences. | Worldwide |
| Valsartan n-Propyl Impurity | Valsartan n-Propyl is an impurity in the synthesis of Valsartan. Group: Biochemicals. Grades: Highly Purified. CAS No. 952652-79-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Valsartan n-Propyl Impurity Benzyl Ester | Valsartan n-Propyl Impurity (V095770) derivative. Group: Biochemicals. Alternative Names: N-(1-Oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine Phenylmethyl Ester. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Valsartan Related Compound A | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Valsartan Related Compound B | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Valsartan Related Compound C | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Valsartan Related Compound E | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| 4-Hydroxy Valsartan Benzyl Ester, Mixture of Diastereomers | 4-Hydroxy Valsartan Benzyl Ester, Mixture of Diastereomers. Group: Biochemicals. Alternative Names: N-(4-Hydroxy-1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-. Grades: Highly Purified. CAS No. 1356929-45-7. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 4-Hydroxy Valsartan ((S)-2-{(4-Hydroxy-pentanoyl)-[2-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]amino}-3-methyl-butyric Acid) | Labelled Valsartan, a nonpeptide angiotensin II AT1-receptor antagonist. Group: Biochemicals. Alternative Names: (S)-2-{(4-Hydroxy-pentanoyl)-[2-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]amino}-3-methyl-butyric Acid. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 4-Oxo Valsartan Benzyl Ester | An intermediate of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Uses: Intermediate for the synthesis of valsartan metabolite. Synonyms: N-(1,4-Dioxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine Phenylmethyl Ester; L-Valine, N-(1,4-dioxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, phenylmethyl ester; (S)-3-Methyl-2-{(4-oxo-pentanoyl)-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-amino}-butyric acid benzyl ester; Benzyl N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-N-(4-oxopentanoyl)-L-valinate; Benzyl N-(4-oxopentanoyl)-N-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-L-valinate. Grade: ≥95%. CAS No. 188240-32-6. Molecular formula: C31H33N5O4. Mole weight: 539.62. | |
| 4-Oxo Valsartan Benzyl Ester | Intermediate for the synthesis of Valsartan metabolite. Group: Biochemicals. Alternative Names: N-(1,4-Dioxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine Phenylmethyl Ester. Grades: Highly Purified. CAS No. 188240-32-6. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Alanine Valsartan | Alanine Valsartan. Group: Biochemicals. Alternative Names: N-(1-Oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-alanine. Grades: Highly Purified. CAS No. 137862-57-8. Pack Sizes: 10mg. Molecular Formula: C22H25N5O3, Molecular Weight: 407.47. US Biological Life Sciences. | Worldwide |
| Des(oxopentyl) Valsartan | An impurity in the synthesis of Valsartan. Group: Biochemicals. Alternative Names: N-[[2'-(2H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine; N-[[2'-(1H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Des(oxopentyl) Valsartan Benzyl Ester | An impurity of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Synonyms: Valsartan desvaleryl benzyl impurity; Benzyl N-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-L-valinate; N-[[2'-(1H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine Benzyl Ester. CAS No. 676129-93-4. Molecular formula: C26H27N5O2. Mole weight: 441.52. | |
| Des(oxopentyl) Valsartan Benzyl Ester | Valsartan intermediate. Group: Biochemicals. Alternative Names: N-[[2'-(1H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine Phenylmethyl Ester; N-[[2'-(1H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine Benzyl Ester. Grades: Highly Purified. CAS No. 676129-93-4. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| D-Valsartan | An R-enantiomer of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Synonyms: Valsartan Impurity A; (2R)-3-Methyl-2-[pentanoyl[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]amino]butanoic acid; (R)-2-(N-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoic acid; ent-Valsartan; Valsartan (R)-enantiomer; N-Pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-D-valine; N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-D-valine; N-Valeryl-N-{[2'-(1H-tetrazole-5-yl)biphenyl-4-yl]methyl}-D-valine; USP Valsartan Related Compound A; Valsartan USP Related Compound A; Valsartan Related Compound A; Valsartan R-enantiomer; Valsartan EP Impurity A. Grade: 95%. CAS No. 137862-87-4. Molecular formula: C24H29N5O3. Mole weight: 435.52. | |
| ent-Valsartan | ent-Valsartan is the (R)-enantiomer of Valsartan. Group: Biochemicals. Grades: Highly Purified. CAS No. 137862-87-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Isoleucine Valsartan | Isoleucine Valsartan. Group: Biochemicals. Alternative Names: N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-Isoleucine. Grades: Highly Purified. CAS No. 137862-78-3. Pack Sizes: 10mg. Molecular Formula: C25H31N5O3, Molecular Weight: 449.55. US Biological Life Sciences. | Worldwide |
| LCZ696 (valsartan + sacubitril) impurity 19 | LCZ696 (valsartan + sacubitril) impurity 19. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,4R)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid. CAS No. 1012341-54-6. Molecular formula: C23H29NO4. Mole weight: 383.48. Catalog: APB1012341546. | |
| LCZ696 (valsartan + sacubitril) impurity 20 | LCZ696 (valsartan + sacubitril) impurity 20. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,4R)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid. CAS No. 1012341-56-8. Molecular formula: C23H29NO4. Mole weight: 383.48. Catalog: APB1012341568. | |
| LCZ696 (valsartan + sacubitril) impurity 21 | LCZ696 (valsartan + sacubitril) impurity 21. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid. CAS No. 1012341-52-4. Molecular formula: C23H29NO4. Mole weight: 383.48. Catalog: APB1012341524. | |
| Sacubitril/Valsartan | Sacubitril/Valsartan (LCZ696), comprised Valsartan and Sacubitril (AHU377) in 1:1 molar ratio, is a first-in-class, orally bioavailable, and dual-acting angiotensin receptor-neprilysin (ARN) inhibitor for hypertension and heart failure [1] [2] [3]. Sacubitril/Valsartan ameliorates diabetic cardiomyopathy by inhibiting inflammation, oxidative stress and apoptosis [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LCZ696. CAS No. 936623-90-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-18204A. | |
| (S)-(-)-Valsartan-[d8] | One of the isotopic labelled form of (S)-(-)-Valsartan, which is a nonpeptide angiotensin II AT1-receptor antagonist and could be used as antihypertensive agent. Synonyms: (S)-(-)-Valsartan-d8(valine-d8); N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl-1,1'-biphenyl)-4-yl]methyl]-L-valine. Grade: 95% by HPLC; 98% atom D. CAS No. 1089736-72-0. Molecular formula: C24H21D8N5O3. Mole weight: 443.57. | |
| Trityl Valsartan n-Propyl Impurity Benzyl Ester | Protected Valsartan impurity. Group: Biochemicals. Alternative Names: N-(1-Oxobutyl)-N-[[2'-(2-trityl-2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Trityl Valsartan Sodium Salt | Valsartan intermediate. Group: Biochemicals. Alternative Names: N-(1-Oxopentyl)-N-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-L-valine Sodium Salt. Grades: Highly Purified. CAS No. 943019-63-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid | 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid is a transformation product of Valsartan (V095750); a nonpeptide angiotensin II AT1-receptor antagonist and antihypertensive. 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid is also referred to as Valsartan acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 164265-78-5. Pack Sizes: 10mg, 100mg. Molecular Formula: C14H10N4O2. US Biological Life Sciences. | Worldwide |
| 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid-d4 | 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid-d4 is the isotope labelled analog of 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid (T308515); a transformation product of Valsartan (V095750) which is a nonpeptide angiotensin II AT1-receptor antagonist and antihypertensive. 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid is also referred to as Valsartan acid. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C14H6D4N4O2. US Biological Life Sciences. | Worldwide |
| 2,5-Dioxopyrrolidine Sacubitril | An impurity of Sacubitril, which is an antihypertensive. The combination drug of sacubitril and valsartan is used for heart failure. Synonyms: (2R,4S)-5-Biphenyl-4-yl-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoic acid ethyl ester. CAS No. 1038924-97-8. Molecular formula: C24H27NO4. Mole weight: 393.483. | |
| 2,5-Dioxopyrrolidine Sacubitril | Sacubitril Impurity 2 is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan. Group: Biochemicals. Grades: Highly Purified. CAS No. 1038924-97-8. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C24H27NO4, Molecular Weight: 393.48. US Biological Life Sciences. | Worldwide |
| (2R,4R)-Sacubitril | (2R,4R)-Sacubitril is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan. Group: Biochemicals. Grades: Highly Purified. CAS No. 766480-48-2. Pack Sizes: 1mg, 5mg. Molecular Formula: C24H29NO5. US Biological Life Sciences. | Worldwide |
| 2R,4R-Sacubitril | An isomer of Sacubitril. Sacubitril is a neprilysin inhibitor that is commonly used in combination with valsartan (an angiotensin II receptor blocker) to form a dual-acting medication known as sacubitril/valsartan. Synonyms: (2R,4R)-Sacubitril; LCZ 696 Impurity B; 4-((rel-(2R,4R)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid; Sacubitril-(2R,4R) Isomer. Grade: 90%. CAS No. 766480-48-2. Molecular formula: C24H29NO5. Mole weight: 411.49. | |
| (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-4-(4-ethoxy-4-oxobutanamido)-2-methylbutanoic acid | (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-4-(4-ethoxy-4-oxobutanamido)-2-methylbutanoic acid is an impurity of Sacubitril, an endopeptidase inhibitor that is effective in the treatment of hypertension and heart failure. Synonyms: Sacubitril impurity 16; Valsartan Impurity; (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-4-(4-ethoxy-4-oxobutanamido)-2-methylbutanoic acid. CAS No. 149709-49-9. Molecular formula: C24H29NO5. Mole weight: 411.49. | |
| (2R,4S)-4-Amino-5-biphenyl-4-yl-2-methylpentanoic acid hydrochloride | An impurity of Sacubitril, a neprilysin inhibitor that is used in combination with valsartan to treat high blood pressure. Synonyms: 1038924-71-8; (2R,4S)-4-amino-5-biphenyl-4-yl-2-methylpentanoic acid hydrochloride(2R,4S)-4-amino-2-methyl-5-(4-phenylphenyl)pentanoic acid; hydrochloride; (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoic acid hydrochloride; SCHEMBL597864. CAS No. 1038924-71-8. Molecular formula: C18H22ClNO2. Mole weight: 319.8. | |
| (2R,4S)-5-Biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methylpentanoic acid | An impurity of Sacubitril, which is an antihypertensive. The combination drug of sacubitril and valsartan is used for heart failure. Synonyms: 1012341-50-2; (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoic acid(2R,4S)-5-biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methylpentanoic acid; FJ7AWX8DMFUNII-FJ7AWX8DMF. CAS No. 1012341-50-2. Molecular formula: C23H29NO4. Mole weight: 383.488. | |
| (2R,4S)-Sacubitril-O-isobutane | (2R,4S)-Sacubitril-O-isobutane is an intermediate in the synthesis of (2S,4S)-Sacubitril (S080915). (2S,4S)-Sacubitril is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan. Group: Biochemicals. Grades: Highly Purified. CAS No. 149709-64-8. Pack Sizes: 500ug, 1mg. Molecular Formula: C28H37NO5. US Biological Life Sciences. | Worldwide |
| (2S,4R)-Sacubitril | (2S,4R)-Sacubitril is the enantiomer and an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan. Group: Biochemicals. Grades: Highly Purified. CAS No. 761373-05-1. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C24H29NO5. US Biological Life Sciences. | Worldwide |
| (2S,4S)-Sacubitril | (2S,4S)-Sacubitril is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan. Group: Biochemicals. Grades: Highly Purified. CAS No. 149709-63-7. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C24H29NO5. US Biological Life Sciences. | Worldwide |
| (2S,4S)-Sacubitril-[d4] | A deuterated sacubitril. Sacubitril is an antihypertensive drug used in combination with valsartan. Synonyms: 4-(((2S,4S)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic-2,2,3,3-d4 acid; (2S,4S)-Sacubitril D4; (2S,4S)-Sacubitril-d4; 3-{[(2S,4S)-1-{[1,1'-biphenyl]-4-yl}-5-ethoxy-4-methyl-5-oxopentan-2-yl]carbamoyl}(D4)propanoic acid; 4-[[(2S,4S)-5-Ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic-d4 acid. Grade: >95%. Molecular formula: C24H25NO5D4. Mole weight: 415.53. | |
| (2S,4S)-Sacubitril-O-isobutane | (2S,4S)-Sacubitril-O-isobutane is an intermediate in the synthesis of (2S,4S)-Sacubitril (S080915). (2S,4S)-Sacubitril is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan. Group: Biochemicals. Grades: Highly Purified. CAS No. 149709-65-9. Pack Sizes: 500ug, 1mg. Molecular Formula: C28H37NO5. US Biological Life Sciences. | Worldwide |
| (3R,5S)-5-Biphenyl-4-ylmethyl-3-methylpyrrolidin-2-one | An impurity of Sacubitril, which is an antihypertensive. The combination drug of sacubitril and valsartan is used for heart failure. Synonyms: 2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)-. CAS No. 1038924-70-7. Molecular formula: C18H19NO. Mole weight: 265.356. | |
| 5-(4'-(azidomethyl)-[1,1'-biphenyl]-2-yl)-1H-tetrazole | An impurity of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Synonyms: 5-(4'-(Azidomethyl)(1,1'-biphenyl)-2-yl)-1H-tetrazole; Valsartan azide impurity. CAS No. 152708-24-2. Molecular formula: C14H11N7. Mole weight: 277.28. | |
| 5-(4'-(Azidomethyl)-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole | An impurity of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Synonyms: 5-[4'-(Azidomethyl)[1,1'-biphenyl]-2-yl]-1-(triphenylmethyl)-1H-tetrazole; 5-[4'-(Azidomethyl)biphenyl-2-yl]-N-trityltetrazole; Valsartan Impurity 1; Valsartan Impurity 20. Grade: ≥95%. CAS No. 124806-66-2. Molecular formula: C33H25N7. Mole weight: 519.60. | |
| 5- [4-bromo methyl - (1, 1-biphenyl) -2-yl] -1-triphenyl methyl tetrazole | An intermediate in the synthesis of Losartan and Valsartan. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
| 5-(4'-Methyl-2-biphenyl)tetrazole-d4 | Labeled Valsartan impurity. Group: Biochemicals. Alternative Names: 5-(4'-Methyl[1,1'-biphenyl]-2-yl)-2H-tetrazole-d4; 2-(Tetrazol-5-yl)-4'-methyl-1,1'-biphenyl-d4. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 6-Chloro 3-Methyl Uracil | 6-Chloro 3-Methyl Uracil is an impurity of Sacubitril. Sacubitril is a prodrug neprilysin inhibitor used in combination with valsartan to reduce the risk of cardiovascular events in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. Synonyms: 6-Chloro-3-methyluracil; 6-Chloro-3-methyl-2,4(1H,3H)-pyrimidinedione; 3-Methyl-6-chlorouracil; 6-Chloro-3-methylpyrimidine-2,4(1H,3H)-dione; 6-Chloro-3-methylpyrimidine-2,4-dione; 6-Chloro-2-hydroxy-3-methylpyrimidin-4(3H)-one. CAS No. 4318-56-3. Molecular formula: C5H5ClN2O2. Mole weight: 160.56. | |
| AHU-377 hemicalcium salt | LCZ696 is a novel single molecule comprising molecular moieties of valsartan and NEP inhibitor prodrug AHU377 (1:1 ratio). Oral administration of LCZ696 caused dose-dependent increases in atrial natriuretic peptide immunoreactivity (due to NEP inhibition) in Sprague-Dawley rats and provided sustained, dose-dependent blood pressure reductions in hypertensive double-transgenic rats. In healthy participants, a randomized, double-blind, placebo-controlled study (n = 80) of single-dose (200-1200 mg) and multiple-dose (50-900 mg once daily for 14 days) oral administration of LCZ696 showed that peak plasma concentrations were reached rapidly for valsartan (1.6-4.9 hours), AHU377 (0.5-1.1 hours), and its active moiety, LBQ657 (1.8-3.5 hours). LCZ696 is superior to valsartan alone in reducing blood pressure. Preliminary results from a Phase II trial showed that LCZ696 reduced NT-proBNP to a greater extent than valsartan alone, and in addition LCZ696 had beneficial effects on symptoms. Synonyms: calcium 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate; AHU337; AHU-337; AHU 337; LCZ696; LCZ 696; LCZ696; Sacubitril. Grade: >98%. CAS No. 1369773-39-6. Molecular formula: C24H28NO5-. Mole weight: 410.48. | |
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