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Valsartan methyl ester (Compound 3) is a derivative of Valsartan (HY-18204). Valsartan methyl ester is an orally active antagonist for angiotensin II , that inhibits angiotensin II ( IC 50 of 0.06 μM), angiotensin II-induced pressor response in rabbit aorta ( IC 50 of 0.068 μM) and angiotensin II-induced pressor response in the pithed rat model (10% inhibition at 10 mg/kg, p.o.) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGP 48933 methyl ester. CAS No. 137863-17-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W414915.
Valsartan Methyl Ester
Valsartan Methyl Ester. Group: Biochemicals. Alternative Names: N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-Valine Methyl Ester; N-(1-Oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-Valine Methyl Ester; N-(1-Oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine Methyl Ester. Grades: Highly Purified. CAS No. 137863-17-3. Pack Sizes: 50mg. Molecular Formula: C25H31N5O3, Molecular Weight: 449.55. US Biological Life Sciences.
Valsartan Desvaleryl Methyl Ester is a derivative of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Synonyms: Des(oxopentyl) Valsartan Methyl Ester; N-[[2'-(2H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, L-Valine, Methyl Ester. Molecular formula: C20H23N5O2. Mole weight: 365.44.
2,5-Dioxopyrrolidine Sacubitril
An impurity of Sacubitril, which is an antihypertensive. The combination drug of sacubitril and valsartan is used for heart failure. Synonyms: (2R,4S)-5-Biphenyl-4-yl-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoic acid ethyl ester. CAS No. 1038924-97-8. Molecular formula: C24H27NO4. Mole weight: 393.483.
4-Hydroxy Valsartan Benzyl Ester, Mixture of Diastereomers
4-Hydroxy Valsartan Benzyl Ester, Mixture of Diastereomers. Group: Biochemicals. Alternative Names: N-(4-Hydroxy-1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-. Grades: Highly Purified. CAS No. 1356929-45-7. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
4-Oxo Valsartan Benzyl Ester
Intermediate for the synthesis of Valsartan metabolite. Group: Biochemicals. Alternative Names: N-(1,4-Dioxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine Phenylmethyl Ester. Grades: Highly Purified. CAS No. 188240-32-6. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Des(oxopentyl) Valsartan Benzyl Ester
Valsartan intermediate. Group: Biochemicals. Alternative Names: N-[[2'-(1H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine Phenylmethyl Ester; N-[[2'-(1H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine Benzyl Ester. Grades: Highly Purified. CAS No. 676129-93-4. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
L-Valine methyl ester hydrochloride
An impurity of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Synonyms: L-Val-OMe HCl; L-Valine, methyl ester, hydrochloride (1:1); L-Valine, methyl ester, monohydrochloride; Valine, methyl ester, hydrochloride, L-; (S)-Valine methyl ester hydrochloride; Methyl (S)-2-amino-3-methylbutanoate hydrochloride; Methyl (S)-valinate hydrochloride; Methyl L-valinate hydrochloride; Methyl L-valine hydrochloride; Methyl valinate hydrochloride; NSC 197198; NSC 22920; Valine methyl ester hydrochloride. Grades: ≥95%. CAS No. 6306-52-1. Molecular formula: C6H13NO2.HCl. Mole weight: 167.63.
Sacubitril-(2S, 4S)-Isomer
Sacubitril-(2S, 4S)-isomer.Sacubitril is a prodrug neprilysin inhibitor used in combination with valsartan to reduce the risk of cardiovascular events in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. Synonyms: (2S,4S)-Sacubitril; 149709-63-7; 4-(((2S,4S)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid; 4-[[(2S,4S)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid; [1,1'-Biphenyl]-4-pentanoic acid, gamma-[(3-carboxy-1-oxopropyl)amino]-alpha-methyl-, alpha-ethyl ester, (alphaS,gammaS)-; LCZ 696 Impurity C; SCHEMBL18059568; DTXSID901127620; AKOS030528363; AS-80403; HY-78841; CS-0009335; 3-{[(2S,4S)-1-{[1,1'-biphenyl]-4-yl}-5-ethoxy-4-methyl-5-oxopentan-2-yl]carbamoyl}propanoic acid; 4-(((2S,4S)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoicacid; alpha-Ethyl (alphaS,gammaS)-gamma-[(3-carboxy-1-oxopropyl)amino]-alpha-methyl[1,1'-biphenyl]-4-pentanoate. Grades: > 95%. CAS No. 149709-63-7. Molecular formula: C24H29NO5. Mole weight: 411.5.
Sacubitril Enantiomer
Sacubitril enantiomer.Sacubitril is a prodrug neprilysin inhibitor used in combination with valsartan to reduce the risk of cardiovascular events in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. Synonyms: 2R,4S-Sacubitril; (2R,4S)-5-(Biphenyl-4-yl)-4-[(3-carboxypropionyl)amino]-2-methylpentanoic acid ethyl ester; 4-[[(2R,4S)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid; (2S,4R)-Sacubitril; SCHEMBL22420467; CS-M3545; AKOS030528367; HY-78847; MS-27102; PD100765; L10003; EN300-6474615; A854860; [1,1'-Biphenyl]-4-pentanoic acid, |A-[(3-carboxy-1-oxopropyl)amino]-|A-methyl-, 4-ethyl ester, (|AS,|AR)-; 3-{[(2R,4S)-1-{[1,1'-biphenyl]-4-yl}-5-ethoxy-4-methyl-5-oxopentan-2-yl]carbamoyl}propanoic acid; 4-(((2R,4S)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid; (alphaS,gammaR)-gamma-[(3-Carboxy-1-oxopropyl)amino]-alpha-methyl-[1,1'-biphenyl]-4-pentanoic acid 4-ethyl ester. Grades: > 95%. CAS No. 761373-05-1. Molecular formula: C24H29NO5. Mole weight: 411.5.
Sacubitril sodium
Sacubitril, also known as AHU377, is a first-in-class medicine that contains a neprilysin (NEP) inhibitor (sacubitril) and an angiotensin II (Ang-II) receptor blocker (valsartan). Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. Synonyms: sodium 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate; Sacubitril sodium; AHU377; AHU 377; AHU-377; LCZ696. CAS No. 149690-05-1. Molecular formula: C24H29NO5.Na. Mole weight: 434.47.
(S)-N-Valeryl-N-([2-(1-H-tetrazole-5-yl)biphenyl-4-yl]methyl)valine Benzyl Ester. Group: Biochemicals. Alternative Names: Valsartan Related Compound C; N-(1-Oxopentyl)-N-[[2?-(2H-tetrazol-5-yl)[1,1?-biphenyl]-4-yl]methyl]-L-valine Phenylmethyl Ester. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C31H35N5O3, Molecular Weight: 525.64. US Biological Life Sciences.
Worldwide
Valsartan benzyl ester
Valsartan benzyl ester. Group: Biochemicals. Alternative Names: N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]; (S)-Benzyl 2-(N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoate. Grades: Highly Purified. CAS No. 137863-20-8. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C31H35N5O3. US Biological Life Sciences.
Worldwide
Valsartan Benzyl Ester N1-Trityl Analog
Valsartan Benzyl Ester N1-Trityl Analog is a synthetic intermediate. Synonyms: N1-Trityl-Valsartan Benzyl Ester; (S)-N-Valeryl-N-([2'-(1-trityl-tetrazol-5-yl)biphenyl-4-yl]methyl)-valine benzyl ester. Molecular formula: C50H49N5O3. Mole weight: 767.98.
Valsartan Benzyl Ester N2-Trityl Analog
Valsartan Benzyl Ester N2-Trityl Analog is a synthetic intermediate. Synonyms: N2-Trityl-Valsartan Benzyl Ester; (S)-N-Valeryl-N-([2'-(2-trityl-tetrazol-5-yl)biphenyl-4-yl]methyl)-valine benzyl ester. Molecular formula: C50H49N5O3. Mole weight: 767.98.
Valsartan Ethyl Ester
An impurity of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Synonyms: N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine Ethyl Ester. CAS No. 1111177-30-0. Molecular formula: C26H33N5O3. Mole weight: 463.58.
Valsartan Isopropyl Ester
An impurity of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Synonyms: N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine 1-Methylethyl Ester; (S)-Isopropyl 2-(N-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoate. CAS No. 1245820-09-0. Molecular formula: C27H35N5O3. Mole weight: 477.61.
Valsartan n-Propyl Impurity Benzyl Ester
Valsartan n-Propyl Impurity (V095770) derivative. Group: Biochemicals. Alternative Names: N-(1-Oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine Phenylmethyl Ester. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Valsartan Related Compound C
Valsartan Related Compound C is an intermediate of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Synonyms: Valsartan Benzyl Ester; N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine Phenylmethyl Ester; USP Valsartan Related Compound C. CAS No. 137863-20-8. Molecular formula: C31H35N5O3. Mole weight: 525.66.
Trityl Valsartan n-Propyl Impurity Benzyl Ester
Protected Valsartan impurity. Group: Biochemicals. Alternative Names: N-(1-Oxobutyl)-N-[[2'-(2-trityl-2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
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