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Tricyclic glycopeptide antibiotic. Inhibits cell wall synthesis in Gram-positive bacteria. Pharmacologically active in vivo. Synonyms: Vancocin; Vancomycinum; Vancomicina; Vancomycine; (S)-3,6-Diamino-hexanoic acid {(3S,9S,12S,15S)-3-((S)-6-hydroxy-2-imino-hexahydro-pyrimidin-4-yl)-9,12-bis-hydroxymethyl-2,5,8,11,14-pentaoxo-6-[1-ureido-meth-(Z)-ylidene]-1,4,7,10,13pentaaza-cyclohexadec-15-yl}-amide. Grade: >98%. CAS No. 1404-90-6. Molecular formula: C66H75Cl2N9O24. Mole weight: 1449.25.
Vancomycin
Vancomycin is an antibiotic for the treatment of bacterial infections. Uses: Scientific research. Group: Natural products. CAS No. 1404-90-6. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 1 g. Product ID: HY-B0671.
Vancomycin
Vancomycin. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1404-90-6. Molecular formula: C66H75Cl2N9O24. Mole weight: 1449.26. Catalog: APB1404906.
The enzyme from the bacterium Amycolatopsis orientalis is involved in the biosynthesis of the glycopeptide antibiotic chloroeremomycin. Group: Enzymes. Synonyms: GtfB (ambiguous). Enzyme Commission Number: EC 2.4.1.310. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2546; vancomycin aglycone glucosyltransferase; EC 2.4.1.310; GtfB (ambiguous). Cat No: EXWM-2546.
Vancomycin Aglycon Trifluoroacetic Acid Salt Hydrate
Vancomycin-[d10] monoacetate salt is the labelled acetate form of Vancomycin. Vancomycin monoacetate salt exhibits potent activity against Gram-positive bacteria, and high effects against MRSA in vitro and in vivo. It interferes with cell wall synthesis by binding to D-alanine-D-alanine residues. Synonyms: [D10]-Vancomycin monoacetate salt; D10-Vancomycin monoacetate salt; Vancomycin-d10 monoacetate salt. Grade: >98%. Molecular formula: C68H69D10Cl2N9O26. Mole weight: 1519.38.
Vancomycin-[d10] trifluoroacetate salt
Labelled Vancomycin trifluoroacetate salt. Vancomycin is a tricyclic glycopeptide antibiotic. It inhibits cell wall synthesis in Gram-positive bacteria. Synonyms: [D10]-Vancomycin (trifluoroacetate salt); Vancomycin-d10 trifluoroacetate salt; Vancomycin-d10 TFA salt. Molecular formula: C66H65D10Cl2N9O24.C2F3O2H. Mole weight: 1573.34.
Vancomycin-[d12] trifluoroacetate salt
Vancomycin-[d12] trifluoroacetate salt is the labelled analogue of Vancomycin trifluoroacetate salt. Vancomycin is a glycopeptide antibiotic medication used to treat a number of bacterial infections. Synonyms: Vancomycin-[d12] TFA salt; Vancomycin trifluoroacetate salt-d12; d12-Vancomycin trifluoroacetate salt. Molecular formula: C66H63D12Cl2N9O24.C2F3O2H. Mole weight: 1575.35.
Vancomycin EP Impurity A
Vancomycin EP Impurity A is a glycopeptide antibiotic produced by Nocardia orientalis A51568.1. Activity against gram-positive bacteria. Synonyms: N2.1-demethylvancomycin B; N-Demethyl Vancomycin B; Norvancomycin; A51568 A. Grade: 95%. CAS No. 91700-98-0. Molecular formula: C65H73Cl2N9O24. Mole weight: 1435.22.
Vancomycin EP Impurity D
Vancomycin EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Desvancosaminylvancomycin B; O4.4-de-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-a-L-lyxo-hexopyranosyl)-ß-D-glucopyranosyl]-O4.4-ß-D-glucopyranosyl-vancomycin B. CAS No. 101485-50-1. Molecular formula: C59H62Cl2N8O22. Mole weight: 1304.34. Catalog: APB101485501.
Vancomycin HCl - pharma grade
Vancomycin HCl - pharma grade. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Vancomycin monohydrochloride. CAS No. 1404-93-9. Molecular formula: C66H75Cl2N9O24·HCl. Mole weight: 1485.71. Product ID: ACM1404939-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: VANCOMYCIN HYDROCHLORIDE.
Vancomycin Hexapeptide
Vancomycin Hexapeptide is a derivative of Vancomycin (V096500), an amphoteric glycopeptide antibiotic produced by Streptomyces orientalis discovered in soil. Inhibits bacterial cell wall synthesis by binding to peptidoglycan. Antibacterial. Group: Biochemicals. Grades: Highly Purified. CAS No. 115236-65-2. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C59H62Cl2N8O23, Molecular Weight: 1322.07. US Biological Life Sciences.
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Vancomycin hydrochloride
1g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C66H75Cl2N9O24.HCl. CAS No. 1404-93-9. Prepack ID 16685638-1g. Molecular Weight 1485.72. See USA prepack pricing.
Vancomycin hydrochloride
5g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C66H75Cl2N9O24.HCl. CAS No. 1404-93-9. Prepack ID 16685638-5g. Molecular Weight 1485.72. See USA prepack pricing.
Vancomycin hydrochloride
The salt of a glycopeptide antibiotic isolated from amycolatopsis orientalis. Vancomycin hydrochloride exhibits potent activity against Gram-positive bacteria, and high effects against MRSA in vitro and in vivo. It interferes with cell wall synthesis by binding to D-alanine-D-alanine residues. Synonyms: Vancomycin HCl; Vancomycin Monohydrochloride. Grade: Assay: 900 ug/mg. CAS No. 1404-93-9. Molecular formula: C66H75Cl2N9O24.HCl. Mole weight: 1485.72.
Vancomycin hydrochloride
Vancomycin hydrochloride is a glycopeptide antibiotic, a hydrochloride of vancomycin, white or white crystalline powder at room temperature. Synonyms: vancocinehydrochloride; LYPHOCIN; VancomycinHydrochloride (4vials, eachvialcontains99, 300mcgofvancomycinactivity); VancomycinHydrochloride (4viChemicalbookals, eachvialcontains100, 500mcgofvancomycinactivity); VANCOMYCIN, HYDROCHLORIDE, STREPTOMYCESORIENTALIS; VANCOR; VANCOCIN; VANCOCINHYDROCHLORIDE. CAS No. 1404-93-9. Product ID: PAP-0058. Molecular formula: C66H76Cl3N9O24. Category: Anti-Infectives. Product Keywords: Antibacterial, Anti-inflammatory and Antiviral Series; Vancomycin hydrochloride; PAP-0058; Anti-Infectives; C66H76Cl3N9O24; 1404-93-9. Appearance: Colorless to faint yellow or tan. Standard: EP. Chemical Name: VancomycinHydrochloride. Grade: Pharmaceutical Grade. Solubility: H2O: 50 mg/mL, clear, yellow. Storage: 4°C, sealed storage, away from moisture. *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). Melting Point: >190°C (dec.). Product Description: Vancomycin hydrochloride is an antibiotic used to study bacterial infections. It works by inhibiting the second stage of cell wall synthesis in susceptible bacteria. Vancomycin hydrochloride also alters membrane permeability and selectively inhibits ribonucleic acid synthesis.
Vancomycin hydrochloride
Vancomycin hydrochloride is an antibiotic for the treatment of bacterial infections. It acts by inhibiting the second stage of cell wall synthesis of susceptible bacteria. Vancomycin also alters the permeability of the cell membrane and selectively inhibits ribonucleic acid synthesis. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 1404-93-9. Purity: 0.9943. Product ID: ACM1404939. Alfa Chemistry ISO 9001:2015 Certified.
Vancomycin hydrochloride
Vancomycin hydrochloride is an antibiotic for the treatment of bacterial infections. It acts by inhibiting the second stage of cell wall synthesis of susceptible bacteria. Vancomycin also alters the permeability of the cell membrane and selectively inhibits ribonucleic acid synthesis. Uses: Scientific research. Group: Natural products. CAS No. 1404-93-9. Pack Sizes: 10 mM * 1 mL; 250 mg; 1 g; 5 g. Product ID: HY-17362.
Vancomycin Hydrochloride
Vancomycin is an aminoglycoside antibiotic, used in the treatment of infections caused by Gram-positive bacteria. vancomycin is not active against Gram-negative bacteria (except some non-gonococcal species of Neisseria). The main target of this antibiotic is the D-alanyl-D-alanine terminal dipeptide of peptidoglycan precursors, used by bacteria for constructing their cell walls. This prevents the reaction used to link peptidoglycan precursors together from taking place. Vancomycin binds with the substrate, not the enzyme, in contrast to the way penicillin inhibits peptidoglycan synthesis.The large hydrophilic molecule is able to form hydrogen bond interactions with the terminal D-alanyl-D-alanine moieties of the NAM/NAG-peptides. Under normal circumstances, this is a five-point interaction. This binding of vancomycin to the D-Ala-D-Ala prevents cell wall synthesis in two ways. It prevents the synthesis of the long polymers of N-acetylmuramic acid (NAM) and N-acetylglucosamine (NAG) that form the backbone strands of the bacterial cell wall, and it prevents the backbone polymers that do manage to form from cross-linking with each other. Group: Biochemicals. Alternative Names: Lyphocin; Meek; Vancocin Hydrochloride; Vancocine Hydrochloride; Vancocyn; Vancor. Grades: Reagent Grade. CAS No. 1404-93-9. Pack Sizes: 5g, 10g, 25g. Molecular Formula: C66H75Cl2N9O24×HCl, Molecular Weight: 1485.7. US Biological Life Sciences.
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Vancomycin pseudoaglycone
Vancomycin pseudoaglycone. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences.
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CBP-aminomethylenevancomycin
CBP-aminomethylenevancomycin is an analogue of vancomycin which overcomes the drug resistance and induces cell permeability. It significantly increases the antibacterial activity and decreases the side effects. Uses: Antibacterial agent. Synonyms: CBP aminomethylenevancomycin.
CBP-C1-aminomethylenevancomycin
CBP-C1-aminomethylenevancomycin is an analogue of vancomycin which overcomes the drug resistance and induces cell permeability. It significantly increases the antibacterial activity and decreases the side effects. Uses: Antibacterial agent. Synonyms: CBP C1 aminomethylenevancomycin.
CBP-iminomethylenevancomycin
CBP-iminomethylenevancomycin is an analogue of vancomycin which overcomes the drug resistance and induces cell permeability. It significantly increases the antibacterial activity and decreases the side effects. Uses: Antibacterial agent. Synonyms: CBP iminomethylenevancomycin.
De-(L-Asn)-L-Gln Vancomycin B
An impurity of Vancomycin. Vancomycin is a glycopeptide antibiotic for the treatment of gram-positive bacteria. Vancomycin exhibits an antibacterial effect by inhibiting bacterial cell wall synthesis. Molecular formula: C67H77Cl2N9O24 HCl. Mole weight: 1499.77.
De-(N-Methyl-D-Leu)-D-Phenylanlanyl Vancomycin B
An impurity of Vancomycin. Vancomycin is a glycopeptide antibiotic for the treatment of gram-positive bacteria. Vancomycin exhibits an antibacterial effect by inhibiting bacterial cell wall synthesis. Molecular formula: C68H71Cl2N9O24. Mole weight: 1469.28.
De-Oxy-(2) Vancomycin B
An impurity of Vancomycin. Vancomycin is a glycopeptide antibiotic for the treatment of gram-positive bacteria. Vancomycin exhibits an antibacterial effect by inhibiting bacterial cell wall synthesis. Molecular formula: C66H75Cl2N9O23. Mole weight: 1433.29.
Desvancosaminyl Vancomycin Trifluoroacetic Acid Salt Hydrate
Vancomycin impurity. Group: Biochemicals. Alternative Names: 2'-O-De (3-amino-2, 3, 6-trideoxy-3-C-methyl-α -L-lyxo-hexopyranosyl) vancomycin Trifluoroacetic Acid Salt Hydrate. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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devancosaminyl-vancomycin vancosaminetransferase
The enzyme, isolated from the bacterium Amycolatopsis orientalis, catalyses the ultimate step in the biosynthesis of the antibiotic vancomycin. Group: Enzymes. Synonyms: devancosaminyl-vancomycin TDP-vancosaminyltransferase; GtfD; dTDP-β-L-vancomycin:desvancosaminyl-vancomycin β-L-vancosaminetransferase; desvancosaminyl-vancomycin vancosaminetransferase. Enzyme Commission Number: EC 2.4.1.322. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2559; devancosaminyl-vancomycin vancosaminetransferase; EC 2.4.1.322; devancosaminyl-vancomycin TDP-vancosaminyltransferase; GtfD; dTDP-β-L-vancomycin:desvancosaminyl-vancomycin β-L-vancosaminetransferase; desvancosaminyl-vancomycin vancosaminetransferase. Cat No: EXWM-2559.
Didechloro Vancomycin xHCl (Vancomycin Impurity)
An impurity in Vancomycin. Group: Biochemicals. Alternative Names: Vancomycin Impurity. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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Epi-(26R) Vancomycin B
Epi-(26R) Vancomycin B is the monohydrochloride of Vancomycin. Vancomycin is a glycopeptide antibiotic for the treatment of gram-positive bacteria. Vancomycin exhibits an antibacterial effect by inhibiting bacterial cell wall synthesis. Uses: Anti-bacterial agents. Synonyms: Vancomycin Monohydrochloride; Lyphocin Monohydrochloride; Meek Monohydrochloride; Vancocin Monohydrochloride; Vancocine Monohydrochloride; Vancocyn Monohydrochloride; Vancor Monohydrochloride. CAS No. 197638-25-8. Molecular formula: C66H75Cl2N9O24 HCl. Mole weight: 1485.71.
Monodechlorovancomycin hydrochloride
A compound derived from the glycopeptide antibiotic, Vancomycin. Synonyms: Monodechlorovancomycin HCl; 10-Dechlorovancomycin hydrochloride. Grade: >95%. Molecular formula: C66H76ClN9O24.xHCl. Mole weight: 1414.81 (free base).
(N-Methyl-Leu) Vancomycin B
An impurity of Vancomycin. Vancomycin is a glycopeptide antibiotic for the treatment of gram-positive bacteria. Vancomycin exhibits an antibacterial effect by inhibiting bacterial cell wall synthesis. Molecular formula: C67H77Cl2N9O24. Mole weight: 1463.31.
Norvancomycin
Norvancomycin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NORVANCOMYCIN; Vancomycin EP Impurity A; Desmethylvancomycin; N-Demethylvancomycin; Antibiotic A 51568A; 22H-8,11:18,21-Dietheno-23,36-(iminomethano)-13,16:31,35-dimetheno-1H,16H-[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine. Product Category: Heterocyclic Organic Compound. CAS No. 91700-98-0. Molecular formula: C65H73Cl2N9O24. Mole weight: 1435.22702;g/mol. Purity: 0.96. IUPACName: Vancomycin, 56-demethyl-. Canonical SMILES: CC1C(C(CC(O1)OC2C(C(C(OC2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)C(C(C(=O)NC(C(=O)NC5C(=O)NC7C8=CC(=C(C=C8)O)C9=C(C=C(C=C9C(NC(=O)C(C(C1=CC(=C(O4)C=C1)Cl)O)NC7=O)C(=O)O)O)O)CC(=O)N)NC(=O)C(CC(C)C)N)O)Cl)CO)O)O)(C)N)O. Density: 1.67±0.1 g/cm³ (20 °C, 760 mmHg). Product ID: ACM91700980. Alfa Chemistry ISO 9001:2015 Certified.
1,3,4,6-Tetra-O-acetyl-2-[(2-aminoacetyl)amino]-2-deoxy-b-D-glucopyranose, a compound of significant importance in the pharmaceutical industry, finds use in the preparation of drugs suited for treating bacterial, viral, and fungal infections. Besides, it serves as a common component in synthesizing glycopeptide antibiotics like vancomycin to boost their antibacterial properties, thereby rendering it a crucial compound to the medicinal fraternity and the ecosystem at large. Synonyms: 1,3,4,6-Tetra-O-acetyl-2-[(2-aminoacetyl)amino]-2-deoxy-a-D-glucopyranose; 1,3,4,6-Tetra-O-acetyl-2-[(2-aminoacetyl)amino]-2-deoxy-b-D-glucopyranose. CAS No. 948565-47-7. Molecular formula: C16H24N2O10. Mole weight: 404.37.
1,3,4,6-Tetra-O-acetyl-2-deoxy-2-N-phthalimido-a-D-glucopyranose, a chemical compound utilized in the production of glycopeptide antibiotics, demonstrates its functional potential as an acyl donor in the course of synthesizing vancomycin derivatives. Resistant against MRSA and other drug-resistance bacteria, these derivatives showcase their potential to alleviate the issues precipitated by such pathogens. Synonyms: 1,3,4,6-Tetraacetyl-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-a-D-glucopyranose. CAS No. 31505-44-9. Molecular formula: C22H23NO11. Mole weight: 477.42.
1-Pyrenemethylamine Hydrochloride
1-Pyrenemethylamine Hydrochloride is used for labelling of various biomolecules. It is used as a reactant in self-assembling vancomycin-pyrene derivatives as hydrogel with potential medical applications. Also used in the preparation of 25, 27-bis (ethylacetoethoxy) -26, 28-dipropyloxycalix [4]arene. Group: Biochemicals. Grades: Highly Purified. CAS No. 93324-65-3. Pack Sizes: 500mg, 1g. Molecular Formula: C17H13N HCl, Molecular Weight: 231.293646. US Biological Life Sciences.
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2,3,4,6-Tetra-O-benzyl-1,5-di-O-mesyl-D-glucitol
2,3,4,6-Tetra-O-benzyl-1,5-di-O-mesyl-D-glucitol, a prominent chemical precursor, plays a vital role in the construction of glycopeptide antibiotics, encompassing prominent strains like vancomycin, eremomycin, and teicoplanin, while it is also extensively involved in the creation of tumor-associated carbohydrate antigens, serving as a valuable synthetic facilitator. Synonyms: [(2S,3R,4S,5R)-5-methylsulfonyloxy-2,3,4,6-tetrakis(phenylmethoxy)hexyl] methanesulfonate. Molecular formula: C36H42O10S2. Mole weight: 698.84.
2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-b-D-thioglucopyranose, commonly known as ATDG, exhibits multifaceted applications in the field of chemistry. It plays a key role in the development of glycopeptide antibiotics, particularly vancomycin, which is renowned for its efficacy against resistant strains of bacteria. With its potential to synthesize chitooligosaccharides, ATDG offers a promising avenue for exploring the biological and pharmaceutical properties of oligosaccharides. Furthermore, this chemical compound acts as a vital reagent in chemical reactions, enabling the synthesis of various multifunctional molecules. Molecular formula: C16H23NO9S. Mole weight: 405.42.
2-Acetamido-2-deoxy-b-D-thioglucopyranose
2-Acetamido-2-deoxy-b-D-thioglucopyranose, a chemical entity that serves as a substrate for glycopeptide and antibiotic assembly, is a pertinent compound in the pharmaceutical domain. Prominent antibiotics such as teicoplanin and vancomycin heavily rely on its synthesis. Moreover, its potential as a formidable weapon against drug-resistant bacterial organisms has not escaped the interest of researchers. Synonyms: Thio-b-D-GlcNAc. CAS No. 781581-10-0. Molecular formula: C8H15NO5S. Mole weight: 237.27.
Used in the preparation of vancomycin-related antibacterial agents. Group: Biochemicals. Alternative Names: N-Decyl-N-(2-oxoethyl)-9H-fluoren-9-ylmethyl Ester; Decyl(2-oxoethyl)-carbamic Acid 9H-Fluoren-9-ylmethyl Ester. Grades: Highly Purified. CAS No. 239088-22-3. Pack Sizes: 10mg. US Biological Life Sciences.
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(3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase
The enzyme, characterized from bacteria Streptomyces toyocaensis and Amycolatopsis orientalis, is involved in the biosynthesis of (3,5-dihydroxyphenyl)glycine, a component of the glycopeptide antibiotic vancomycin. Group: Enzymes. Synonyms: DpgC. Enzyme Commission Number: EC 1.13.11.80. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0601; (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase; EC 1.13.11.80; DpgC. Cat No: EXWM-0601.
3,5-dihydroxyphenylacetyl-CoA synthase
The enzyme, characterized from the bacterium Amycolatopsis mediterranei, is involved in biosynthesis of the nonproteinogenic amino acid (S)-3,5-dihydroxyphenylglycine, a component of the vancomycin-type antibiotic balhimycin. Group: Enzymes. Synonyms: DpgA. Enzyme Commission Number: EC 2.3.1.246. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2195; 3,5-dihydroxyphenylacetyl-CoA synthase; EC 2.3.1.246; DpgA. Cat No: EXWM-2195.
4-hydroxymandelate oxidase
A flavoprotein (FMN). The enzyme from the bacterium Amycolatopsis orientalis is involved in the biosynthesis of L-(4-hydroxyphenyl)glycine and L-(3,5-dihydroxyphenyl)glycine, two non-proteinogenic amino acids occurring in the vancomycin group of antibiotics. Group: Enzymes. Synonyms: 4HmO; HmO. Enzyme Commission Number: EC 1.1.3.46. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0419; 4-hydroxymandelate oxidase; EC 1.1.3.46; 4HmO; HmO. Cat No: EXWM-0419.
4-hydroxymandelate synthase
Requires Fe2+. Involved in the biosynthesis of the vancomycin group of glycopeptide antibiotics. Group: Enzymes. Synonyms: 4-hydroxyphenylpyruvate dioxygenase II. Enzyme Commission Number: EC 1.13.11.46. CAS No. 280566-04-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0564; 4-hydroxymandelate synthase; EC 1.13.11.46; 280566-04-3; 4-hydroxyphenylpyruvate dioxygenase II. Cat No: EXWM-0564.
7-Chloro-1-O-methylemodin
It is produced by the strain of Fusarium aquaedeductuum WC-5228. It inhibits the binding activity of type B endothelin-1 (ETB) receptor with IC50 of 50 μmol/L. It has antibacterial activities against Gram-positive bacteria, including vancomycin-resistant Enterococcus faecium and methicillin-resistant Staphylococcus aureus. Synonyms: 7-Chloro-6,8-dihydroxy-1-meth-oxy-3-methylanthraquinone; 1,3-dihydroxy-8-methoxy-2-chloro-6-methylanthraquinone. CAS No. 19267-89-1. Molecular formula: C16H11ClO5. Mole weight: 318.71.
A-42867
A-42867 is a glycopeptide antibiotic produced by Nocardia sp. It has activity against Gram-positive bacteria, mycobacteria, Enterococcus faecalis and Clostridium difficile. Synonyms: Antibiotic 42867; 22-O-(3-Amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-44-O-de(2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyl)-44-O-(O-(6-deoxy-alpha-D-mannopyranosyl)-D-glucosyl)vancomycin. CAS No. 122753-17-7. Molecular formula: C72H86ClN9O28. Mole weight: 1560.95.
Acremonidin A
Acremonidins A to approximately E (1 to approximately 5) were produced by fermentation of Acremonium sp. LL-Cyan 416, in heterogeneous phases. Acremonidins A showed moderate activity against Gram-positive bacteria, including the methicillin-resistant staphylococci and vancomycin-resistant enterococci. Molecular formula: C33H26O12. Mole weight: 614.56.
Acremonidin B
Acremonidins A to approximately E (1 to approximately 5) were produced by fermentation of Acremonium sp. LL-Cyan 416, in heterogeneous phases. Acremonidins B showed moderate activity against Gram-positive bacteria, including the methicillin-resistant staphylococci and vancomycin-resistant enterococci. Molecular formula: C31H24O11. Mole weight: 572.52.
Auriclosene
Auriclosene is a potent and Broad spectrum antimicrobial agent. It is highly effective in in vitro studies against multi-drug resistant bacteria including Methicillin-resistant Staphylococcus aureus (MRSA) and Vancomycin-resistant Enterococcus (VRE). Phase III clinical trials for the treatment of Impetigo are on-going. Uses: Impetigo. Synonyms: NVC-422; NVC 422; NVC422; CD07223; CD-07223; CD 07223; Auriclosene. UNII-BKR7Y95229; 2-(dichloroamino)-2-methylpropane-1-sulfonic acid. Grade: 98%. CAS No. 846056-87-9. Molecular formula: C4H9Cl2NO3S. Mole weight: 222.08.
Balhimycin
It is produced by the strain of Amycolatopsis sp. 8621022. Balhimycin has the activity of congela-positive bacteria (including MRSA) similar to vancomycin. Synonyms: DB04111; balhimycin. CAS No. 140932-79-2. Molecular formula: C66H73Cl2N9O24. Mole weight: 1447.23.
Benzyl 2-Acetamido-3-O-(1-carboxyethyl)4,6-O-benzylidene-2-deoxy-α-D-glucopyranoside (Mixture of Diastereomers)
Benzyl 2-Acetamido-3-O-(1-carboxyethyl)4,6-O-benzylidene-2-deoxy-α-D-glucopyranoside (Mixture of Diastereomers) is a profound biomedical compound, exhibiting inhibitory efficacy against compound-resistant bacterials, exemplified by methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). Synonyms: α-Muramic acid, N-acetyl-1-O-(phenylmethyl)-4,6-O-(phenylmethylene)-, (7ξ)-; Glucopyranoside, benzyl 2-acetamido-4,6-O-benzylidene-3-O-(L-1-carboxyethyl)-2-deoxy-, α-D-; α-D-Glucopyranoside, phenylmethyl 2-(acetylamino)-3-O-(1-carboxyethyl)-2-deoxy-4,6-O-(phenylmethylene)-. CAS No. 15008-41-0. Molecular formula: C25H29NO8. Mole weight: 471.50.
Benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-a-D-muramic acid, an indispensable entity within the realm of biomedicine, unfolds its prominence in successfully combating antibiotic resistance. With its exceptional chemical composition, this compound not only serves as a fundamental building block but also exhibits formidable antibacterial attributes, directing its focus towards the intricate cellular frameworks of bacteria. Heralded as a beacon of hope, its profound efficacy provides a ray of light in the face of drug-resistant infections inflicted by perilous bacteria strains such as methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). Synonyms: (2R)-2-(((4aR,6S,7R,8R,8aS)-7-Acetamido-6-(benzyloxy)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-8-yl)oxy)propanoic acid; Benzyl N-Acetyl-4,6-O-benzylidene-alpha-D-muramic Acid. CAS No. 2862-3-5. Molecular formula: C25H29NO8. Mole weight: 471.50.
Carbazomycin G
Carbazomycin G is a potent antibiotic derived from Streptomyces carbazoleicus used for studying a wide range of drug-resistant bacterial infections, including Methicillin-resistant Staphylococcus aureus (MRSA) and Vancomycin-resistant Enterococcus (VRE). Synonyms: 1-Hydroxy-1,2-dimethyl-3-methoxy-1H-carbazol-4(9H)-one. Grade: 96%. CAS No. 115920-44-0. Molecular formula: C15H15NO3. Mole weight: 257.28.
Cefathiamidine
It is produced by the strain of Semisynthetic first generation cephalosporin for injection. Cefathiamidin has better antibacterial activity than cefazolin, cefuroxime and cefamidin against Streptococcus pneumoniae, Streptococcus pyogenes, MSSA, MSSE and Moraxella mucosa inflammation, and it showed strong activity against enterococcus. Its MIC90 (2.0 ?/mL)is slightly weaker than vancomycin (1.0?/mL). It also has some activity to MRSA and MRSE. Synonyms: (6R-trans)-3-[(Acetyloxy)methyl]-7-[[[[[(1-methylethyl)amino][(1-methylethyl)imino]methyl]thio]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; 7-[2-[(N,N'-diisopropylamidino)thio]acetamido]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; Cephathiamidine. Grade: > 95%. CAS No. 33075-00-2. Molecular formula: C19H28N4O6S2. Mole weight: 472.58.
Ceftobiprole
Ceftobiprole (Ro 63-9141) is a broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci with a MIC 90 value of 2 μg/mL for MRSA. Ceftobiprole also inhibits gram-positive and gram-negative pathogens. Ceftobiprole can be used for the study of hospital-acquired pneumonia (excluding ventilator-associated pneumonia) and community-acquired pneumonia [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 63-9141; BAL 9141. CAS No. 209467-52-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112579.
Ceftobiprole
Ceftobiprole (Ro 63-9141) is a broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci with a MIC90 value of 2 μg/mL for MRSA. Ceftobiprole also inhibits gram-positive and gram-negative pathogens. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Ceftobiprole;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2Z)-2-(5-aMino-1,2,4-thiadiazol-3-yl)-2-(hydroxyiMino)acetyl]aMino]-8-oxo-3-[(E)-[(3R)-2-oxo[1,3-bipyrrolidin]-3-ylidene]Methyl]-,(6R,7R)-. Product Category: Inhibitors. CAS No. 209467-52-7. Molecular formula: C20H22N8O6S2. Mole weight: 534.576. Purity: ≥95.0%. Product ID: ACM209467527. Alfa Chemistry ISO 9001:2015 Certified.
Ceftobiprole medocaril sodium
Ceftobiprole medocaril (BAL5788) sodium is the parenteral proagent of Ceftobiprole (HY-112579). Ceftobiprole is a parenteral pyrrolidinone cephalosporin. Ceftobiprole is a broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci. Ceftobiprole also inhibits gram-positive and gram-negative pathogens [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAL5788 sodium. CAS No. 252188-71-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-106574A.
Chloptosin B
Chloptosins B is a dimeric cyclohexapeptide discovered from the culture broth of Embleya sp. MM621-AF10. Chloptosins demonstrated potent antimicrobial activity against Gram-positive bacteria including drug-resistant strains of methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci with MICs of 0.5-2 μg/ml.
Chloptosin C
Chloptosins C is a dimeric cyclohexapeptide discovered from the culture broth of Embleya sp. MM621-AF10. Chloptosins demonstrated potent antimicrobial activity against Gram-positive bacteria including drug-resistant strains of methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci with MICs of 0.5-2 μg/ml.
Chloroorienticin A
Chloroorienticin A is produced by the strain of Amycolatopsis orientalis (Nocardia orientalis) PA-45052. Each component of Chloroorienticin had anti-Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA) activity, and the activity was stronger than that of orientalis and vancomycin. Synonyms: Chloroeremomycin. CAS No. 118395-73-6. Molecular formula: C73H88Cl2N10O26. Mole weight: 1592.43.
Chloroorienticin B
Chloroorienticin B is produced by the strain of Amycolatopsis orientalis (Nocardia orientalis) PA-45052. Each component of Chloroorienticin had anti-Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA) activity, and the activity was stronger than that of orientalis and vancomycin. Synonyms: Dihydrobalhimycin. CAS No. 118373-81-2. Molecular formula: C66H75Cl2N9O24. Mole weight: 1449.25.
Chloroorienticin C
Chloroorienticin C is produced by the strain of Amycolatopsis orientalis (Nocardia orientalis) PA-45052. Each component of Chloroorienticin had anti-Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA) activity, and the activity was stronger than that of orientalis and vancomycin. Synonyms: Vancomycin, 22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-arabino-hexopyranosyl)-14-O-de(2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-arabino-hexopyranosyl)-beta-D-glucopyranosyl)-. CAS No. 118373-82-3. Molecular formula: C60H65Cl2N9O19. Mole weight: 1287.11.
Chloroorienticin D
Chloroorienticin D is produced by the strain of Amycolatopsis orientalis (Nocardia orientalis) PA-45052. Each component of Chloroorienticin had anti-Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA) activity, and the activity was stronger than that of orientalis and vancomycin. Synonyms: Vancomycin, 22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-arabino-hexopyranosyl)-56-methyl-. CAS No. 118373-83-4. Molecular formula: C74H90Cl2N10O26. Mole weight: 1606.46.
Chloroorienticin E
Chloroorienticin E is produced by the strain of Amycolatopsis orientalis (Nocardia orientalis) PA-45052. Each component of Chloroorienticin had anti-Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA) activity, and the activity was stronger than that of orientalis and vancomycin. Synonyms: Vancomycin, 22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-arabino-hexopyranosyl)-2'-O-de(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-arabino-hexopyranosyl)-56-methyl-. CAS No. 118373-84-5. Molecular formula: C67H77Cl2N9O24. Mole weight: 1463.28.
Cilastatin
Prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct.Cilastatin is an inhibitor of dipeptidase (dehydropeptidase I), a renal dipeptidase.1 It inhibits human renal dipeptidase (Ki = 0.7uM), porcine dipeptidase (IC50 = 0.11uM), and bacterial metallo- β-lactamase CphA from A. hydrophila (IC50 = 178uM).1,2,3 Cilastatin (200ug/ml) protects primary porcine renal proximal tubular epithelial cells from nephrotoxicity and apoptosis induced by vancomycin.4 In a mouse model of systemic infection, cilastatin in combination with imipenem protects mice from S. aureus, E. coli, and P. aeruginosa infection.5 Cilastatin was designed to inhibit renal metabolism of imipenem and prolong its half-life.2 Formulations containing cilastatin in combination with imipenem have been used to treat susceptible bacterial infections. Group: Biochemicals. Alternative Names: (2Z) -7- [ [ (2R) -2-amino-2-carboxyethyl] thio] -2- [ [ [ (1S) -2, 2-dimethylcyclopropyl] carbonyl] amino] -2-heptenoic Acid; MK-791. Grades: Highly Purified. CAS No. 82009-34-5. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??N?O?S, Molecular Weight: 358.45. US Biological Life Sciences.
Worldwide
Collinone
It is produced by the strain of Streptomuces coelicolor CH999. It has anti-gram-positive bacterial activity including methicillin-resistant staphylococcus aureus (MRSA) and vancomycin resistant enterococcus (VRE). MIC is 16-32 μg/mL. It has no effect on gram-negative bacteria, fungi and viruses. It is toxic to HeLa, Vero, MT-4 and other tumor cells. CAS No. 343315-22-0. Molecular formula: C27H18O12. Mole weight: 534.42.
D-Ala-D-Ala dipeptidase
A Zn2+-dependent enzyme. The enzyme protects Enterococcus faecium from the antibiotic vancomycin, which can bind to the -D-Ala-D-Ala sequence at the C-terminus of the peptidoglycan pentapeptide (see diagram). This enzyme reduces the availability of the free dipeptide D-Ala-D-Ala, which is the precursor for this pentapeptide sequence, allowing D-Ala-(R)-lactate (for which vancomycin has much less affinity)to be added to the cell wall instead. The enzyme is stereospecific, as L-Ala-L-Ala, D-Ala-L-Ala and L-Ala-D-Ala are not substrates. Belongs in peptidase family M15. Group: Enzymes. Synonyms: D-alanyl-D-alanine dipeptidase; vanX D-Ala-D-Ala dipeptidase; VanX. Enzyme Commission Number: EC 3.4.13.22. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4036; D-Ala-D-Ala dipeptidase; EC 3.4.13.22; D-alanyl-D-alanine dipeptidase; vanX D-Ala-D-Ala dipeptidase; VanX. Cat No: EXWM-4036.
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