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Glyptins are class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase. Aside from there use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic. Uses: Dipeptidyl-peptidase iv inhibitors. Synonyms: LAF237; LAF 237; LAF-237; Galvus; NVP-LAF 237; Zomelis; Xiliarx; Jalra; DSP 7238; DSP-7238; DSP7238; Vildagliptin; Zomelis. Grade: 98%. CAS No. 274901-16-5. Molecular formula: C17H25N3O2. Mole weight: 303.406.
Vildagliptin
It is a new oral anti-hyperglycemic agent of a new dipeptidyl peptidase-IV (DPP-IV) inhibitor class of drugs. Antidiabetic. Group: Biochemicals. Grades: Highly Purified. CAS No. 274901-16-5. Pack Sizes: 10mg. US Biological Life Sciences.
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Vildagliptin
Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV ( DPP-IV ) inhibitor with an IC 50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LAF237; NVP-LAF 237. CAS No. 274901-16-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-14291.
Vildagliptin
Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Unii-I6B4B2U96p; Laf 237; Galvus. Product Category: Inhibitors. Appearance: white crystalline powder. CAS No. 274901-16-5. Molecular formula: C17H25N3O2. Mole weight: 303.4. Purity: 0.98. IUPACName: (2S)-1-[2-[(3-hydroxy-1-adamantyl)amino]acetyl]pyrrolidine-2-carbonitrile. Canonical SMILES: C1CC(N(C1)C(=O)CNC23CC4CC(C2)CC(C4)(C3)O)C#N. Density: 1.27 g/cm³. Product ID: ACM274901165. Alfa Chemistry ISO 9001:2015 Certified.
Vildagliptin Carboxylic Acid Lithium Salt Hydrate
The major metabolite of Vildagliptin. Group: Biochemicals. Alternative Names: N-(3-Hydroxytricyclo[3. 3. 1. 13, 7]dec-1-yl)glycyl-. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
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Vildagliptin-[d6]
Vildagliptin-[d6] is the labeled analogue of Vildagliptin. Vildagliptin is a new dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. Synonyms: Vildagliptin D6; Vildagliptin-d6; (2S)-1-[[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-pyrrolidine-2-carbonitrile-3,3,4,4,5,5-d6; (S)-1-[2-[(3-Hydroxyadamant-1-yl)amino]acetyl]pyrrolidine-2-carbonitrile-3,3,4,4,5,5-d6; Vidagliptin-d6; Xiliarx-d6. Grade: >95%. CAS No. 2747956-23-4. Molecular formula: C17H19N3O2D6. Mole weight: 309.44.
Vildagliptin-[d7]
Vildagliptin-[d7] is the labelled analogue of Vildagliptin, a DPP-4 inhibitor used as an anti-diabetic drug. Synonyms: Vildagliptin D7. Grade: 98% by HPLC; 98% atom D. CAS No. 1133208-42-0. Molecular formula: C17H18D7N3O2. Mole weight: 310.4.
Vildagliptin Impurity 1
Vildagliptin Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1036959-27-9. Molecular formula: C17H25N3O2. Mole weight: 303.41. Catalog: APB1036959279.
Vildagliptin Impurity 2
Vildagliptin Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1036959-23-5. Molecular formula: C24H33N5O3. Mole weight: 439.56. Catalog: APB1036959235.
Vildagliptin Impurity 22
Vildagliptin Impurity 22. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1032564-18-3. Molecular formula: C12H19NO3. Mole weight: 225.29. Catalog: APB1032564183.
Vildagliptin Impurity 26
Vildagliptin Impurity 26. Uses: For analytical and research use. Group: Impurity standards. CAS No. 108-80-5. Molecular formula: C3H3N3O3. Mole weight: 129.08. Catalog: APB108805.
Vildagliptin ( (S) -1-[N- (3-hydroxy-1-adamantyl) glycyl]pyrrolidine-2-carbonitrile)
An antidiabetic agent. A potent inhibitor of dipeptidyl peptidase IV (DPP IV), an enzyme that breaks down Glucagon-like peptide 1 (GLP-1). By delaying the degradation of GLP-1, vildagliptin extends the action of insulin while also suppressing the release of glucagon. This leads to a reduction in elevated blood glucose levels (hyperglycemia), which is a characteristic feature of type 2 diabetes. Group: Biochemicals. Grades: Highly Purified. CAS No. 274901-16-5. Pack Sizes: 10mg. US Biological Life Sciences.
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(2R)-Vildagliptin
(2R)-Vildagliptin is an oral anti-hyperglycemic agent that inhibit dipeptidyl peptidase 4 (DPP-4) which can act as a serine exopeptidase. Aside from there use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic. Group: Biochemicals. Grades: Highly Purified. CAS No. 1036959-27-9. Pack Sizes: 10mg, 100mg. Molecular Formula: C17H25N3O2. US Biological Life Sciences.
Worldwide
(2R)-Vildagliptin
(2R)-Vildagliptin is an R-enantiomer of Vildagliptin, which is a dipeptidyl peptidase-4 (DPP-4) inhibitor used as an anti-hyperglycemic agent and an anti-diabetic drug. Synonyms: Vildagliptin Related Compound A; (2R)-1-[2-[[(5S,7R)-3-hydroxy-1-adamantyl]amino]acetyl]pyrrolidine-2-carbonitrile. Grade: ≥ 98%. CAS No. 1036959-27-9. Molecular formula: C17H25N3O2. Mole weight: 303.406.
Dehydroxy Vildagliptin
Dehydroxy Vildagliptin is an impurity of Vildagliptin. It is an oral anti-hyperglycemic agent (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: (R)-1-(2-((3S,5S,7S)-Adamantan-1-ylamino)acetyl)pyrrolidine-2-carbonitrile; Vildagliptin impurity G. Molecular formula: C17H25N3O. Mole weight: 287.4.
Hydroxy Vildagliptin
Hydroxy Vildagliptin is an impurity of Vildagliptin. It is an oral anti-hyperglycemic agent (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: (S)-1-(((1R,3R,5S,7S)-3,5-dihydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile. Molecular formula: C17H25N3O3. Mole weight: 319.41.
Hydroxy Vildagliptin
Hydroxy Vildagliptin. Uses: For analytical and research use. Group: Impurity standards. IUPAC Name: (2S)-1-[2-[(3,5-dihydroxy-1-adamantyl)amino]acetyl]pyrrolidine-2-carbonitrile. Molecular formula: C17H25N3O3. Mole weight: 319.40. Catalog: APS001940. SMILES: OC12CC3CC(O)(C1)CC(C3)(C2)NCC(=O)N4CCC[C@H]4C#N. Format: Neat.
(R)-Vildagliptin Impurity 61 Tosylate
(R)-Vildagliptin Impurity 61 Tosylate is an impurity of Vildagliptin. It is an oral anti-hyperglycemic agent (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: (R)-pyrrolidine-2-carbonitrile, 4-methylbenzenesulfonate (1:1). Molecular formula: C12H16N2O3S. Mole weight: 268.33.
1,3-Diazidoadamantane
1,3-Diazidoadamantane is an impurity of Vildagliptin. It is an oral anti-hyperglycemic agent (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: 1,3-Diazidotricyclo[3.3.1.13,7]decane; (1s,3s,5s,7s)-1,3-Diazidoadamantane. CAS No. 908245-26-1. Molecular formula: C10H14N6. Mole weight: 218.26.
1-Amino-3-adamantanol
Reagent used in the preparation of Vildagliptin. Group: Biochemicals. Alternative Names: 3-Amino-1-adamantanol; 3-Amino-tricyclo[3.3.1.13, 7]decan-1-ol; 1-Amino-3-hydroxyadamantane; (3-Hydroxyadamantan-1-yl)amine. Grades: Highly Purified. CAS No. 702-82-9. Pack Sizes: 100mg. US Biological Life Sciences.
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1-Amino-3-nitroadamantane
1-Amino-3-nitroadamantane has potential application in co-catalyst for transition metal reactions and maybe a useful intermediate for the synthesis of Vildagliptin (V305000), an antidiabetic drug that inhibits dipeptidyl peptidase 4 (DPP-4). Vildagliptin exhibits antioxidant properties and may be an apoptotic compound against pancreatic cancer cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 243145-00-8. Pack Sizes: 100mg, 500mg. Molecular Formula: C10H16N2O2, Molecular Weight: 196.25. US Biological Life Sciences.
Worldwide
1-Amino-3-nitroadamantane
Vildagliptin Impurity 29 is an impurity of Vildagliptin. It is an oral anti-hyperglycemic agent (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: Vildagliptin Impurity 29; 3-Nitrotricyclo[3.3.1.13,7]decan-1-amine. CAS No. 243145-00-8. Molecular formula: C10H16N2O2. Mole weight: 196.25.
1-methylpyrrolidine-2-carbonitrile
1-methylpyrrolidine-2-carbonitrile is an impurity of Vildagliptin. It is an oral anti-hyperglycemic agent (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: Vildagliptin Impurity 8; Vildagliptin Carbonitrile Impurity. CAS No. 20297-37-4. Molecular formula: C6H10N2. Mole weight: 110.16.
2-((1R, 3R, 5R, 7R)-3-Hydroxyadamantan-1-yl)hexahydropyrrolo[1, 2-a]pyrazine-1, 4-dione is a Vildagliptin (V305000) impurity that is used in the synthetic preparation of Vildagliptin diketopiperazine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 50mg. Molecular Formula: C17H24N2O3, Molecular Weight: 304.38. US Biological Life Sciences.
Worldwide
(2R)-1-(2-Chloroacetyl)-2-pyrrolidinecarbonitrile
(2R)-1-(2-Chloroacetyl)-2-pyrrolidinecarbonitrile is an impurity of Vildagliptin. It is an oral anti-hyperglycemic agent (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: Vildagliptin Impurity 12; Vildagliptin Chloroacetyl Nitrile (R)-Isomer. CAS No. 565452-98-4. Molecular formula: C7H9ClN2O. Mole weight: 172.61.
(2S, 2'S) -1, 1'- [ [ (3- hydroxytri cyclo [3. 3. 1. 13, 7] dec-1-yl) imino] bis (1-oxo-2, 1-ethane diyl) ] bis-2-pyrrolidinecarbonitri le is an impurity of Vildagliptin (V305000) which is an oral anti-hyperglycemic agent that inhibit dipeptidyl peptidase 4 (DPP-4). Group: Biochemicals. Grades: Highly Purified. CAS No. 1036959-23-5. Pack Sizes: 50mg, 100mg. Molecular Formula: C24H33N5O3. US Biological Life Sciences.
Worldwide
3-Aminoadamantan-1-ol
An impurity of Vildagliptin. Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. Synonyms: 3-Amino-1-hydroxyadamantane; 1-Amino-3-adamantanol; Tricyclo[3.3.1.13,7]decan-1-ol, 3-amino-; 1-Adamantanol, 3-amino-; 3-Aminotricyclo[3.3.1.13,7]decan-1-ol; (3-Hydroxyadamantan-1-yl)amine; 1-Amino-3-hydroxyadamantane; 3-Amino-1-adamantanol. Grade: ≥95%. CAS No. 702-82-9. Molecular formula: C10H17NO. Mole weight: 167.25.
5-Aminotricyclo[3.3.1.13,7]decane-1,3-diol
5-Aminotricyclo[3.3.1.13,7]decane-1,3-diol is an impurity of Vildagliptin. It is an oral anti-hyperglycemic agent (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: 5-aminoadamantane-1,3-diol; 3,5-dihydroxyadamantan-1-amine. CAS No. 1382839-19-1. Molecular formula: C10H17NO2. Mole weight: 183.25.
(8aS)-3-hydroxyhexahydropyrrolo[1,2-a]pyrazine-1,4-dione is an impurity of Vildagliptin. It is an oral anti-hyperglycemic agent (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: Vildagliptin Impurity 17 (Mixture of Diastereomers). CAS No. 1846606-32-3. Molecular formula: C7H10N2O3. Mole weight: 170.17.
Adamantane-1,3,5,7-tetraol
Adamantane-1,3,5,7-tetraol is an impurity of Vildagliptin. It is an oral anti-hyperglycemic agent (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: Vildagliptin Impurity 28. Grade: ≥95%. CAS No. 16104-28-2. Molecular formula: C10H16O4. Mole weight: 200.23.
H-Pro-NH2
An impurity of Vildagliptin. Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. Synonyms: L-Prolinamide; (2S)-2-Pyrrolidinecarboxamide; (-)-Prolinamide; (2S)-2-Carbamoylpyrrolidine; (2S)-Pyrrolidine-2-carboxylic acid amide; (S)-2-(Aminocarbonyl)pyrrolidine; (S)-Prolinamide; (S)-Proline Amide; 2-Pyrrolidinecarboxamide, (2S)-; 2-Pyrrolidinecarboxamide, (S)-; Prolinamide, L-; (S)-Pyrrolidine-2-carboxamide; (S)-Pyrrolidine-2-carboxylic acid amide; L-Proline amide. Grade: ≥95%. CAS No. 7531-52-4. Molecular formula: C5H10N2O. Mole weight: 114.10.
(R)-1-(2-hydroxyacetyl)pyrrolidine-2-carbonitrile
(R)-1-(2-hydroxyacetyl)pyrrolidine-2-carbonitrile is an impurity of Vildagliptin. It is an oral anti-hyperglycemic agent (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: Vildagliptin Impurity 57. Molecular formula: C7H10N2O2. Mole weight: 154.17.
(R)-1-glycylpyrrolidine-2-carbonitrile, hydrochloride (1:1) is an impurity of Vildagliptin. It is an oral anti-hyperglycemic agent (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: Vildagliptin Impurity 53 HCl. Molecular formula: C7H12N3OCl. Mole weight: 189.65.
(S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile
An impurity of Vildagliptin. Vildagliptin is a new dipeptidyl peptidase-4 (DPP-4) inhibitor used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. Synonyms: (2S)-1-(2-Chloroacetyl)-2-pyrrolidinecarbonitrile; 2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)-, (2S)-; (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile; (2S)-1-Chloroacetylpyrrolidine-2-carbonitrile; (2S)-N-Chloroacetyl-2-cyanopyrrolidine; Vildagliptin Chloroacetyl Nitrile; (S)-1-(Chloroacetyl)pyrrolidine-2-carbonitrile; 1-(2-Chloroacetyl)-(2S)-pyrrolidine carbonitrile; 1-Chloroacetyl-2-(S)-cyanopyrrolidine. Grade: ≥95%. CAS No. 207557-35-5. Molecular formula: C7H9ClN2O. Mole weight: 172.61.
(S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxamide
An impurity of Vildagliptin. Vildagliptin is a new dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. Synonyms: (2S)-1-(2-Chloroacetyl)-2-pyrrolidinecarboxamide; 2-Pyrrolidinecarboxamide, 1-(chloroacetyl)-, (2S)-; Vildagliptin Chloroacetyl Amide (S)-Isomer; 1-(2-Chloroacetyl)-2-(S)-pyrrolidine carboxamide; 1-(Chloroacetyl)-L-prolinamide; Vildagliptin Chloroacetyl Amide Impurity. Grade: 95%. CAS No. 214398-99-9. Molecular formula: C7H11ClN2O2. Mole weight: 190.63.
(S)-1-(2-hydroxyacetyl)pyrrolidine-2-carbonitrile
(S)-1-(2-hydroxyacetyl)pyrrolidine-2-carbonitrile is an impurity of Vildagliptin. It is an oral anti-hyperglycemic agent (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. CAS No. 1563006-28-9. Molecular formula: C7H10N2O2. Mole weight: 154.17.
(S)-1-(Hydroxyacetyl)-2-pyrrolidinecarboxamide
Vildagliptin Impurity 43 is an impurity of Vildagliptin. It is an oral anti-hyperglycemic agent (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: Vildagliptin Impurity 43. CAS No. 96166-39-1. Molecular formula: C7H12N2O3. Mole weight: 172.18.
An impurity of Vildagliptin. Vildagliptin is a new dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. Synonyms: Vildagliptin Dione Impurity; 2-[(1r,3r,5R,7S)-3-hydroxyadamantan-1-yl]-octahydropyrrolo[1,2-a]piperazine-1,4-dione. CAS No. 1844894-70-7. Molecular formula: C17H24N2O3. Mole weight: 304.38.
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