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| Product | Description | |
|---|---|---|
| Vincristine | Vincristine. CAS No: 57-22-7 |  Sarchem Laboratories New Jersey NJ |
| Vincristine | Vincristine. Group: Biochemicals. Grades: Plant Grade. CAS No. 57-22-7. Pack Sizes: 20mg. US Biological Life Sciences. |  Worldwide |
| Vincristine Chloromethiodide | Vincristine Chloromethiodide is an impurity of Vincristine (V314250), An antitumor alkaloid isolated from Vinca rosea Linn. An antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C47H58ClIN4O10, Molecular Weight: 1001.34. US Biological Life Sciences. | Worldwide |
| Vincristine Chloromethiodide-d5 | Vincristine Chloromethiodide-d5 is the labeled analogue of Vincristine Chloromethiodide (V314230), an impurity of Vincristine (V314250), An antitumor alkaloid isolated from Vinca rosea Linn. An antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C47H53D5ClIN4O10, Molecular Weight: 1006.37. US Biological Life Sciences. | Worldwide |
| Vincristine-D3 | Vincristine-D3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246817-09-3. Molecular formula: C46H53D3N4O10. Mole weight: 827.99. Catalog: APB1246817093. |  |
| Vincristine-d3 Sulfate | Labelled Vincristine. An antitumor alkaloid isolated from Vinca rosea Linn. An antineoplastic. Group: Biochemicals. Alternative Names: 22-Oxovincaleukoblastine-d3 Sulfate. Grades: Highly Purified. CAS No. 1217854-24-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Vincristine-d6 Sulfate | Vincristine-d6 Sulfate. Group: Biochemicals. Alternative Names: 22-Oxovincaleukoblastine-d6 Sulfate. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Vincristine Impurity 4 | Vincristine Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246812-06-5. Molecular formula: C46H56N4O11. Mole weight: 840.97. Catalog: APB1246812065. | |
| Vincristine M1 | Vincristine M1. CAS No: 910580-56-2 | Sarchem Laboratories New Jersey NJ |
| Vincristine N-Oxide | Potential treatment for hyperproliferative disorders. Group: Biochemicals. Alternative Names: 22-Oxo-vincaleukoblastine 6'-Oxide. Grades: Highly Purified. CAS No. 947527-73-3. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Vincristine sulfate | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardschiral moleculeseuropean pharmacopoeia (ph. eur.)pharmacopoeial standards. Alternative Names: Methyl (3aR,4R,5S,5aR,10bR,13aR)-4-(acetyloxy)-3a-ethyl-9-[(5S,7R,9S)-5-ethyl-5-hydroxy-9-(methoxycarbonyl)-1,4,5,6,7,8,9,10-octahydro-2H-3,7-methanoazacycloundecino[5,4-b]indol-9-yl]-6-formyl-5-hydroxy-8-methoxy-3a,4,5,5a,6,11,12,13a-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate sulfate,Vincristine sulfate. | |
| Vincristine sulfate | Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a K i of 85 nM. Uses: Scientific research. Group: Natural products. Alternative Names: Leurocristine sulfate; NSC-67574 sulfate; 22-Oxovincaleukoblastine sulfate. CAS No. 2068-78-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-N0488. |  |
| Vincristine Sulfate | An antitumor alkaloid isolated from Vinca rosea Linn. An antineoplastic. Group: Biochemicals. Grades: Highly Purified. CAS No. 2068-78-2. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??N?O??S. US Biological Life Sciences. | Worldwide |
| Vincristine sulfate (assay) | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Vincristine Sulfate Liposome | Vincristine sulfate is in the vinca alkaloid family that exerts its cell cycle-specific antitumor effects by affecting spindle microtubule formation through inhibition of microtubule protein polymerization. This product is a PEGylated pre-formulated liposome with vincristine sulfate. It is only for research purposes. Group: Drug-loaded liposome. Categories: vincristine sulfate; 2068-78-2. |  |
| Vincristine sulfate salt | 95.0-105.0% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| 3',4'-Anhydro Vincristine Ditartrate | A derivative of Vinblastine, an antitumor alkaloid. Group: Biochemicals. Alternative Names: 3',4'-Didehydro-4'-deoxy-22-oxo-vincaleukoblastine Ditartrate; 3',4'-Anhydroleurocristine Ditartrate; 3',4'-Anhydrovincristine Ditartrate; Anhydroleurocristine Ditartrate; Anhydrovincristine Ditartrate. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 4'-Deoxy Vincristine | A Vincristine. Group: Biochemicals. Alternative Names: 4'-Deoxy-22-oxo-vincaleukoblastine; 4'-Deoxyleurocristine. Grades: Highly Purified. CAS No. 68135-16-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 4-Desacetyl 3-deoxy vincristine | 4-Desacetyl 3-deoxy vincristine. Group: Biochemicals. Alternative Names: 4-Deacetyl-3-deoxyvincristine; O4-Deacetyl-3-deoxy-22-oxo-vincaleukoblastine; 4-Deacetyl-3-deoxyleurocristine. Grades: Highly Purified. CAS No. 99435-53-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C44H54N4O8. US Biological Life Sciences. | Worldwide |
| 4-Desacetyl 3-Deoxy Vincristine | 4-Desacetyl 3-Deoxy Vincristine is a degradation product of Vincristine. Vincristine is a vinca alkaloid with antitumor property used for the treatment of kinds of cancers, including acute lymphocytic leukemia, acute myeloid leukemia, Hodgkin's disease, neuroblastoma, and small cell lung cancer. Synonyms: 4-Deacetyl-3-deoxyvincristine; O4-Deacetyl-3-deoxy-22-oxo-vincaleukoblastine; 4-Deacetyl-3-deoxyleurocristine; Methyl (2β,3α,4β,5α,12β,19α)-15-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-1-formyl-4-hydroxy-16-methoxy-6,7-didehydroaspidospermidine-3-carboxylate. Grade: ≥95%. CAS No. 99435-53-7. Molecular formula: C44H54N4O8. Mole weight: 766.92. |  |
| 4-Desacetyl vincristine methosulfate | 4-Desacetyl vincristine methosulfate. Group: Biochemicals. Alternative Names: O4-Deacetyl-22-oxo-vincaleukoblastine methosulfate; 4-Deacetyl leurocristine. Grades: Highly Purified. CAS No. 3704-1-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C45H58N4O13S. US Biological Life Sciences. | Worldwide |
| N-Desformyl-4-desacetyl Vincristine Disulfate Salt | Derivative of an antitumor alkaloid. Group: Biochemicals. Alternative Names: O4-Deacetyl-1-demethyl-vincaleukoblastine Disulfate Salt; Desacetyl Desformyl Vincristine Disulfate Salt. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| N-Formyl leurosine (vincristine impurity G) | N-Formyl leurosine (vincristine impurity G). Group: Biochemicals. Alternative Names: (3'a,4'a)-4'-Deoxy-3',4'-epoxy-22-oxovincaleukoblastine. Grades: Highly Purified. CAS No. 54022-49-0. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C46H54N4O10. US Biological Life Sciences. | Worldwide |
| 5-N-Acetylardeemin | 5-N-Acetylardeemin is a heterocyclic compound isolated from Aspergillus fischeri var.brasiliensis AB 1826 M-35. 5-N-Acetylardeemin can enhance the cytotoxicity of the antineoplastic drug vincristine to multi-drug resistant human tumor cells. Synonyms: 5-N-Acetylardeemin; N-Acetylardeemin. CAS No. 148441-26-3. Molecular formula: C28H28N4O3. Mole weight: 468.55. | |
| (+)-Aphidicolin | Antibiotic. Reversible inhibitor of eukaryotic nuclear DNA replication. Useful for cell synchronization. Blocks the cell cycle at early S phase. Prolongs the half life of DNA methyltransferase. Specific DNA polymerase alpha and delta inhibitor in eukaryotic cells and in some viruses of animal origin. Acts synergistically with vincristine and doxorubicin. Apoptosis inhibitor/inducer. Group: Biochemicals. Alternative Names: [3R-(3α, 4α, 4aα, 6a β,8 β,9 β,11a β,11b β ) ]-Tetradecahydro-3, 9-dihydroxy-4, 11b-dimethyl-8, 11a-methano-11aH-cyclohepta [a]naphthalene-4, 9-dimethanol; Aphidicolin; ICI 69653; NSC 234714; (3α, 4α, 5α, 17α)-3, 17-Dihydroxy-4-methyl-9, 15-cyclo-C, 18-dinor-14, 15-secoandrostane-4, 17-dimethanol; (3R, 4R, 4aR, 6aS, 8R, 9R, 11aS, 11bS) -Tetradecahydro-3, 9-dihydroxy-4, 11b-dimethyl-8, 11a-methano-11aH-cyclohepta [a]naphthalene-4, 9-dimethanol. Grades: Highly Purified. CAS No. 38966-21-1. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C20H34O4, Molecular Weight: 338.48. US Biological Life Sciences. | Worldwide |
| Asiaticoside | Antibacterial. Human collagen I synthesis inducer. Anti-wrinkle activity. Shows wound healing activity. Enhances normal human skin cell migration, attachment and growth. Suppresses collagen expression and TGF-beta/Smad signaling by inducing Smad7 and inhibiting TGF-betaRI and TGF-betaRII. Anti-inflammatory. Anti-gastric ulcer. Mitogen-activated protein kinases (MAPKs), nuclear factor-kappaB (NF-kappaB), cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS; NOSII) expression, production of serum tumor necrosis factor (TNF-alpha) and interleukin-6 (IL-6) inhibitor. Apoptosis inducer in cancer cells. Enhances antitumor activity of vincristine in cancer cells. Might be useful in cancer chemotherapy. Anxiolytic. Antidepressant-like activity. Hepatoprotective effects. CYP2C19 and CYP3A4 inhibitor. Neuroprotective. Antileishmanial activity. cPLA2 and sPLA2 inhibitor. Group: Biochemicals. Alternative Names: Blastostimulina, Centelase, Emdecassol, Madecassol, Marticassol, FK1080, BRN 0078195, NSC 166062. Grades: Highly Purified. CAS No. 16830-15-2. Pack Sizes: 10mg, 50mg. Molecular Formula: C48H78O19. US Biological Life Sciences. | Worldwide |
| BE-10988 | BE-10988 is a topoisomerase-II inhibitor produced by Str. sp. BA 10988. It has the activity of inhibiting P388 murine leukemia cells. It inhibits P388 (P388S), vincristine-doxorubicin-resistant P388 (P388/VCR) and doxorubicin-resistant P388 (P388/MDR) cells with IC50 (μmol/L) of 0.5, 0.4, 2.0, respectively. CAS No. 135261-89-1. Molecular formula: C13H10N4O3S. Mole weight: 302.31. | |
| BE-12406 A | BE-12406 A is an antitumor antibiotic produced by Streptomyces rutrersensis subsp. castelarensis. It has the activity of inhibiting murine P388 leukemia cells (IC50 is 0.8 μmol/L), and has the same activity against vincristine-doxorubicin resistant strains (P388/VCR) (IC50 is 0.2 μmol/L). It can inhibit the growth of S480 ascites carcinoma in mice. Synonyms: BE 12406A; 6H-Benzo(d)naphtho(1,2-b)pyran-6-one, 12-((6-deoxy-alpha-L-mannopyranosyl)oxy)-1-hydroxy-10-methoxy-8-methyl-. CAS No. 132417-96-0. Molecular formula: C25H24O9. Mole weight: 468.45. | |
| BE-12406 B | BE-12406 B is an antitumor antibiotic produced by Streptomyces rutrersensis subsp. castelarensis. It has the activity of inhibiting murine P388 leukemia cells (IC50 is 7 μmol/L), and has the same activity against vincristine-doxorubicin resistant strains (P388/VCR) (IC50 is 7 μmol/L). It can inhibit the growth of S480 ascites carcinoma in mice. Synonyms: 12-((6-Deoxyhexopyranosyl)oxy)-1,10-dihydroxy-8-methyl-6H-benzo(d)naphtho(1,2-b)pyran-6-one. CAS No. 132417-97-1. Molecular formula: C24H22O9. Mole weight: 454.43. | |
| Bortezomib-d15 | Bortezomib, sold under the brand name Velcade among others, is an anti-cancer medication used to treat multiple myeloma and mantle cell lymphoma. Bortezomib is a dipeptide boronic acid derivative that reversibly inhibits the 20S proteasome with Ki of 0.6 nM. It binds the β5-subunit of the 20S proteasome and selectively inhibits chymotryptic activity. Bortezomib blocks the degradation of tumor-suppressing and proapoptotic proteins to induce cell cycle arrest and apoptosis in cancer cell lines. New studies show that bortezomib may potentially help recover from vincristine treatment in treating acute lymphoblastic leukemia, when replacing vincristine in the process. Synonyms: LDP-341-d5; MG-341-d5; PS-341-d5. Grade: ≥99% atom D. Molecular formula: C57H54D15B3N12O9. Mole weight: 1113.76. | |
| Dehydronitrosonisoldipine | Dehydronitrosonisoldipine, a derivative of Nisoldipine (HY-17402), is an irreversible and cell-permeant sterile alpha and TIR motif-containing 1 (SARM1) inhibitor. Dehydronitrosonisoldipine acts mainly by blocking SARM1 activation but not its enzymatic activities. Dehydronitrosonisoldipine inhibits SARM1 and axon degenration (AxD) by covalently modifying cysteines, also inhibits the Vincristine-activated cADPR production in neurons. Dehydronitrosonisoldipine can be used for researching neurodegenerative disorders[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 87375-91-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-Z0816. | |
| Desacetyl Vindoline | Precursor to Vindoline during Vincristine biosynthesis. Group: Biochemicals. Alternative Names: (2 β,3 β,4 β, 5α, 12R, 19α)-6, 7-Didehydro-3, 4-dihydroxy-16-methoxy-1-methyl-aspidospermidine-3-carboxylic Acid Methyl Ester; 4-Desacetylvindoline; Deacetylvindoline; NSC 91993. Grades: Highly Purified. CAS No. 3633-92-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Elacridar hydrochloride (GF 120918, P-gp inhibitor, (N-[4-[2- (3, 4-Dihydro-6, 7-dimethoxy-2 (1H) -isoquinolinyl) ethyl]phenyl]-9, 10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide hydrochloride) | P-glycoprotein (P-gp/ABCG1) inhibitor. Blocks P-gp-mediated multidrug resistance (MDR) of the cytotoxic drugs doxorubicin and vincristine in CHRC5 cells. Also inhibits breast cancer resistance protein (BCRP/ABCG2). Orally active. Group: Biochemicals. Grades: Highly Purified. CAS No. 143851-98-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Mps1-IN-3 hydrochloride | Mps1-IN-3 hydrochloride is a potent and selective Mps1 inhibitor with an IC 50 value of 50 nM. Mps1-IN-3 hydrochloride can inhibit the proliferation of glioblastoma cells, and effectively sensitizes glioblastomas to Vincristine in orthotopic glioblastoma xenograft model [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2989453-29-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12401A. | |
| Phomopsin A | Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis. Phomopsin A is a noncompetitive inhibitor of the binding of radiolabeled vincristine to tubulin [1]. Uses: Scientific research. Group: Natural products. CAS No. 64925-80-0. Pack Sizes: 1 mg. Product ID: HY-N6793. | |
| Piperafizine A | It is a methylated diketopiperazine formed by the condensation of phenylalanine and is produced by many species in the genus Streptomyces. It exhibits little activity in vitro but potentiates vincristine antitumour potency. Synonyms: 3,6-Dibenzylidene-1-methyl-2,5-dioxopiperazine. Grade: >99% by HPLC. CAS No. 130603-59-7. Molecular formula: C19H16N2O2. Mole weight: 304.34. | |
| Piperafizine A (3,6-Dibenzylidene-1-methyl-2,5-dioxopiperazine) | Piperafizine A is a methylated diketopiperazine formed by the condensation of phenylalanine and produced by a number of species in the Streptomyces genus. Piperafizine A exhibits little activity in vitro but has been seen to potentiate vincristine antitumor potency. The mechanism of action has not been characterized. Group: Biochemicals. Alternative Names: 3,6-Dibenzylidene-1-methyl-2,5-dioxopiperazine. Grades: Highly Purified. CAS No. 130603-59-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Rubiginone B2 | Antibiotic with vincristine-cytotoxicity potentiating activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 130548-10-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| SARPAGINE | Sarpagine is a natural alkaloid found in the roots of Alstonia yunnanensis Diels, it is effective in reversing multidrug-resistance (MDR) in vincristine-resistant KB cells. Synonyms: Sarpagan-10,17-diol; Raupine; Sarpagane-10,17-diol. Grade: >97%. CAS No. 482-68-8. Molecular formula: C19H22N2O2. Mole weight: 310.4. | |
| Scholaricine | Scholaricine comes from the herbs of Bothrocaryum controversum, and Scholaricine reverses multidrug resistance in vincristine-resistant KB cells. Uses: Anti-inflammatory and analgesic effect. Synonyms: Methyl (19S)-12,19-dihydroxy-2,16-didehydrocuran-17-oate. Grade: > 95%. CAS No. 99694-90-3. Molecular formula: C20H24N2O4. Mole weight: 356.4. | |
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