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| Product | Description | |
|---|---|---|
| Vincristine | Vincristine. CAS No: 57-22-7 |  Sarchem Laboratories New Jersey NJ |
| Vincristine | Vincristine. Group: Biochemicals. Grades: Plant Grade. CAS No. 57-22-7. Pack Sizes: 20mg. US Biological Life Sciences. |  Worldwide |
| Vincristine | Vincristine. Uses: For analytical and research use. Group: Impurity standards. CAS No. 57-22-7. Molecular Formula: C46H56N4O10. Mole Weight: 824.97. Catalog: APB57227. |  |
| Vincristine Chloromethiodide | Vincristine Chloromethiodide is an impurity of Vincristine (V314250), An antitumor alkaloid isolated from Vinca rosea Linn. An antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C47H58ClIN4O10, Molecular Weight: 1001.34. US Biological Life Sciences. | Worldwide |
| Vincristine Chloromethiodide-d5 | Vincristine Chloromethiodide-d5 is the labeled analogue of Vincristine Chloromethiodide (V314230), an impurity of Vincristine (V314250), An antitumor alkaloid isolated from Vinca rosea Linn. An antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C47H53D5ClIN4O10, Molecular Weight: 1006.37. US Biological Life Sciences. | Worldwide |
| Vincristine-D3 | Vincristine-D3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246817-09-3. Molecular Formula: C46H53D3N4O10. Mole Weight: 827.99. Catalog: APB1246817093. | |
| Vincristine-d3 Sulfate | A labeled chemotherapy medication. Used to treat multiple types of cancers. Inhibits mitosis causing cells death. Binds to tubulin protein, prohibiting chromosome separation during metaphase. Mainly used for non-Hodgkin's lymphoma. Group: 2h labeled compounds. Alternative Names: 22-Oxovincaleukoblastine-d3 Sulfate; Leurocristine-d3 Sulfate; Kyocristine-d3; Lilly 37231-d3; NSC 67574-d3; Novopharm-d3; Oncovin-d3; Onkovin-d3; VCR Sulfate-d3; Vincasar PFS-d3; Vincrisul-d3. CAS No. 1217854-24-4. Molecular formula: C46H55D3N4O14S. Mole weight: 926.05. Catalog: ACM1217854244. |  |
| Vincristine-d3 Sulfate | Labelled Vincristine. An antitumor alkaloid isolated from Vinca rosea Linn. An antineoplastic. Group: Biochemicals. Alternative Names: 22-Oxovincaleukoblastine-d3 Sulfate. Grades: Highly Purified. CAS No. 1217854-24-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Vincristine-d6 Sulfate | Vincristine-d6 Sulfate. Group: Biochemicals. Alternative Names: 22-Oxovincaleukoblastine-d6 Sulfate. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Vincristine EP Impurity B | Vincristine EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 68135-16-0. Molecular Formula: C46H56N4O9. Mole Weight: 808.97. Catalog: APB68135160. | |
| Vincristine EP Impurity C | Vincristine EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 18172-50-4. Molecular Formula: C45H56N4O9. Mole Weight: 796.96. Catalog: APB18172504. | |
| Vincristine EP Impurity D | Vincristine EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 3704-1-6. Molecular Formula: C44H54N4O9. Mole Weight: 782.94. Catalog: APB3704016. | |
| Vincristine EP Impurity E | Vincristine EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 3352-69-0. Molecular Formula: C44H56N4O8. Mole Weight: 768.95. Catalog: APB3352690. | |
| Vincristine EP Impurity F (Vinorelbine EP Impurity E) | Vincristine EP Impurity F (Vinorelbine EP Impurity E). Uses: For analytical and research use. Group: Impurity standards. CAS No. 23360-92-1. Molecular Formula: C46H56N4O9. Mole Weight: 808.97. Catalog: APB23360921. | |
| Vincristine EP Impurity F (Vinorelbine EP Impurity E) Sulfate | Vincristine EP Impurity F (Vinorelbine EP Impurity E) Sulfate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 54081-68-4. Molecular Formula: C46H58N4O13S. Mole Weight: 907.05. Catalog: APB54081684. | |
| Vincristine EP Impurity G | Vincristine EP Impurity G. Uses: For analytical and research use. Group: Impurity standards. CAS No. 54022-49-0. Molecular Formula: C46H54N4O10. Mole Weight: 822.96. Catalog: APB54022490. | |
| Vincristine EP Impurity H (vinblastine) | Vincristine EP Impurity H (vinblastine). Uses: For analytical and research use. Group: Impurity standards. CAS No. 865-21-4. Molecular Formula: C46H58N4O9. Mole Weight: 810.99. Catalog: APB865214. | |
| Vincristine EP Impurity H (vinblastine) Sulfate | Vincristine EP Impurity H (vinblastine) Sulfate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 143-67-9. Molecular Formula: C46H60N4O13S. Mole Weight: 909.06. Catalog: APB143679. | |
| Vincristine (free base) | The attenuating effect of VC in Vincristine-induced nociceptive painful sensation may be due to its potential of antioxidative, neuroprotective and calcium channel inhibitory action. Uses: Antitumor. Synonyms: 22-Oxovincaleukoblastine; Leurocristine; rel-Vincristine; NSC-67574; Kyocristine. Grades: >98%. CAS No. 57-22-7. Molecular formula: C46H56N4O10. Mole weight: 824.96. |  |
| Vincristine Impurity 2 | Vincristine Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 910580-56-2. Molecular Formula: C45H54N4O10. Mole Weight: 810.95. Catalog: APB910580562. | |
| Vincristine Impurity 4 | Vincristine Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246812-06-5. Molecular Formula: C46H56N4O11. Mole Weight: 840.97. Catalog: APB1246812065. | |
| Vincristine Impurity 5 | Vincristine Impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 55855-88-4. Molecular Formula: C44H56N4O7. Mole Weight: 752.95. Catalog: APB55855884. | |
| Vincristine Impurity D | An impurity of Vincristine. Vincristine is a vinca alkaloid with an antitumor property used for the treatment of kinds of cancers, including acute lymphocytic leukemia, acute myeloid leukemia, Hodgkin's disease, neuroblastoma, and small cell lung cancer. Synonyms: Deacetyl Vincristine. Molecular formula: C44H54N4O9. Mole weight: 782.94. | |
| Vincristine Impurity G | Vincristine Impurity G is a degradation product of Vincristine. Vincristine is a vinca alkaloid with an antitumor property used for the treatment of kinds of cancers, including acute lymphocytic leukemia, acute myeloid leukemia, Hodgkin's disease, neuroblastoma, and small cell lung cancer. Synonyms: N-Formyl Leurosine; (3'α,4'α)-4'-Deoxy-3',4'-epoxy-22-oxovincaleukoblastine; 22-Oxoleurosine; F-Leurosine; Formylleurosine; Leuroformine; N-Demethyl-N-formylleurosine; N-Formyl N-demethylleurosine; NSC 269419; Vinformide. CAS No. 54022-49-0. Molecular formula: C46H54N4O10. Mole weight: 822.96. | |
| Vincristine Impurity I | An impurity of Vincristine. Vincristine is a vinca alkaloid with an antitumor property used for the treatment of kinds of cancers, including acute lymphocytic leukemia, acute myeloid leukemia, Hodgkin's disease, neuroblastoma, and small cell lung cancer. Synonyms: Methyl Vincristine; Vincristine Methiodide; 6'-Methylleurocristinium Iodide; N6'-Methylleurocristinium Iodide; 1H-Indolizino[8,1-cd]carbazole Vincaleukoblastinium Deriv.; 2H-3,7-Methanoazacycloundecino[5,4-b]indole Vincaleukoblastinium Deriv.; Leurocristine Methiodide; 6'-Methyl-22-oxo-vincaleukoblastinium Iodide. CAS No. 4724-00-9. Molecular formula: C47H59N4O10.I. Mole weight: 966.92. | |
| Vincristine Impurity J | An impurity of Vincristine. Vincristine is a vinca alkaloid with an antitumor property used for the treatment of kinds of cancers, including acute lymphocytic leukemia, acute myeloid leukemia, Hodgkin's disease, neuroblastoma, and small cell lung cancer. Synonyms: DCM Adduct of Vincristine. Molecular formula: C47H58ClN4O10.Cl. Mole weight: 909.91. | |
| Vincristine Impurity K | Vincristine Impurity K is an impurity of Vincristine that has the potential to treat hyperproliferative disorders. Synonyms: Vincristine N-Oxide; 22-Oxo-vincaleukoblastine 6'-Oxide. CAS No. 947527-73-3. Molecular formula: C46H56N4O11. Mole weight: 840.98. | |
| Vincristine Impurity L | An impurity of Vincristine. Vincristine is a vinca alkaloid with an antitumor property used for the treatment of kinds of cancers, including acute lymphocytic leukemia, acute myeloid leukemia, Hodgkin's disease, neuroblastoma, and small cell lung cancer. Synonyms: Hydroxy Vinamidine. Molecular formula: C46H56N4O11. Mole weight: 840.98. | |
| Vincristine M1 | Vincristine M1. CAS No: 910580-56-2 | Sarchem Laboratories New Jersey NJ |
| Vincristine N-Oxide | Potential treatment for hyperproliferative disorders. Group: Biochemicals. Alternative Names: 22-Oxo-vincaleukoblastine 6'-Oxide. Grades: Highly Purified. CAS No. 947527-73-3. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Vincristine sulfate | Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a K i of 85 nM. Uses: Scientific research. Group: Natural products. Alternative Names: Leurocristine sulfate; NSC-67574 sulfate; 22-Oxovincaleukoblastine sulfate. CAS No. 2068-78-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-N0488. |  |
| Vincristine Sulfate | An antitumor alkaloid isolated from Vinca rosea Linn. An antineoplastic. Group: Biochemicals. Grades: Highly Purified. CAS No. 2068-78-2. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??N?O??S. US Biological Life Sciences. | Worldwide |
| Vincristine Sulfate | Vincristine is an inhibitor of polymerization of microtubules by binding to tubulin with IC50 of 32 μM. Uses: Anti-cancer. Synonyms: Leurocristine. Grades: >98%. CAS No. 2068-78-2. Molecular formula: C46H58N4O14S. Mole weight: 923.04. | |
| Vincristine Sulfate Liposome | Vincristine sulfate is in the vinca alkaloid family that exerts its cell cycle-specific antitumor effects by affecting spindle microtubule formation through inhibition of microtubule protein polymerization. This product is a PEGylated pre-formulated liposome with vincristine sulfate. It is only for research purposes. Group: Drug-loaded liposome. Categories: vincristine sulfate; 2068-78-2. |  |
| 3',4'-Anhydro Vincristine Ditartrate | A derivative of Vinblastine, an antitumor alkaloid. Group: Biochemicals. Alternative Names: 3',4'-Didehydro-4'-deoxy-22-oxo-vincaleukoblastine Ditartrate; 3',4'-Anhydroleurocristine Ditartrate; 3',4'-Anhydrovincristine Ditartrate; Anhydroleurocristine Ditartrate; Anhydrovincristine Ditartrate. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 4'-Deoxy Vincristine | A Vincristine. Group: Biochemicals. Alternative Names: 4'-Deoxy-22-oxo-vincaleukoblastine; 4'-Deoxyleurocristine. Grades: Highly Purified. CAS No. 68135-16-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 4-Desacetyl 3-deoxy vincristine | 4-Desacetyl 3-deoxy vincristine. Group: Biochemicals. Alternative Names: 4-Deacetyl-3-deoxyvincristine; O4-Deacetyl-3-deoxy-22-oxo-vincaleukoblastine; 4-Deacetyl-3-deoxyleurocristine. Grades: Highly Purified. CAS No. 99435-53-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C44H54N4O8. US Biological Life Sciences. | Worldwide |
| 4-Desacetyl vincristine methosulfate | 4-Desacetyl vincristine methosulfate. Group: Biochemicals. Alternative Names: O4-Deacetyl-22-oxo-vincaleukoblastine methosulfate; 4-Deacetyl leurocristine. Grades: Highly Purified. CAS No. 3704-1-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C45H58N4O13S. US Biological Life Sciences. | Worldwide |
| N-Desformyl-4-desacetyl Vincristine Disulfate Salt | Derivative of an antitumor alkaloid. Group: Biochemicals. Alternative Names: O4-Deacetyl-1-demethyl-vincaleukoblastine Disulfate Salt; Desacetyl Desformyl Vincristine Disulfate Salt. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| N-Formyl leurosine (vincristine impurity G) | N-Formyl leurosine (vincristine impurity G). Group: Biochemicals. Alternative Names: (3'a,4'a)-4'-Deoxy-3',4'-epoxy-22-oxovincaleukoblastine. Grades: Highly Purified. CAS No. 54022-49-0. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C46H54N4O10. US Biological Life Sciences. | Worldwide |
| 5-N-Acetylardeemin | 5-N-Acetylardeemin is a heterocyclic compound isolated from Aspergillus fischeri var.brasiliensis AB 1826 M-35. 5-N-Acetylardeemin can enhance the cytotoxicity of the antineoplastic drug vincristine to multi-drug resistant human tumor cells. Synonyms: 5-N-Acetylardeemin; N-Acetylardeemin. CAS No. 148441-26-3. Molecular formula: C28H28N4O3. Mole weight: 468.55. | |
| (+)-Aphidicolin | Antibiotic. Reversible inhibitor of eukaryotic nuclear DNA replication. Useful for cell synchronization. Blocks the cell cycle at early S phase. Prolongs the half life of DNA methyltransferase. Specific DNA polymerase alpha and delta inhibitor in eukaryotic cells and in some viruses of animal origin. Acts synergistically with vincristine and doxorubicin. Apoptosis inhibitor/inducer. Group: Biochemicals. Alternative Names: [3R-(3α, 4α, 4aα, 6a β,8 β,9 β,11a β,11b β ) ]-Tetradecahydro-3, 9-dihydroxy-4, 11b-dimethyl-8, 11a-methano-11aH-cyclohepta [a]naphthalene-4, 9-dimethanol; Aphidicolin; ICI 69653; NSC 234714; (3α, 4α, 5α, 17α)-3, 17-Dihydroxy-4-methyl-9, 15-cyclo-C, 18-dinor-14, 15-secoandrostane-4, 17-dimethanol; (3R, 4R, 4aR, 6aS, 8R, 9R, 11aS, 11bS) -Tetradecahydro-3, 9-dihydroxy-4, 11b-dimethyl-8, 11a-methano-11aH-cyclohepta [a]naphthalene-4, 9-dimethanol. Grades: Highly Purified. CAS No. 38966-21-1. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C20H34O4, Molecular Weight: 338.48. US Biological Life Sciences. | Worldwide |
| Asiaticoside | Antibacterial. Human collagen I synthesis inducer. Anti-wrinkle activity. Shows wound healing activity. Enhances normal human skin cell migration, attachment and growth. Suppresses collagen expression and TGF-beta/Smad signaling by inducing Smad7 and inhibiting TGF-betaRI and TGF-betaRII. Anti-inflammatory. Anti-gastric ulcer. Mitogen-activated protein kinases (MAPKs), nuclear factor-kappaB (NF-kappaB), cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS; NOSII) expression, production of serum tumor necrosis factor (TNF-alpha) and interleukin-6 (IL-6) inhibitor. Apoptosis inducer in cancer cells. Enhances antitumor activity of vincristine in cancer cells. Might be useful in cancer chemotherapy. Anxiolytic. Antidepressant-like activity. Hepatoprotective effects. CYP2C19 and CYP3A4 inhibitor. Neuroprotective. Antileishmanial activity. cPLA2 and sPLA2 inhibitor. Group: Biochemicals. Alternative Names: Blastostimulina, Centelase, Emdecassol, Madecassol, Marticassol, FK1080, BRN 0078195, NSC 166062. Grades: Highly Purified. CAS No. 16830-15-2. Pack Sizes: 10mg, 50mg. Molecular Formula: C48H78O19. US Biological Life Sciences. | Worldwide |
| BE-10988 | BE-10988 is a topoisomerase-II inhibitor produced by Str. sp. BA 10988. It has the activity of inhibiting P388 murine leukemia cells. It inhibits P388 (P388S), vincristine-doxorubicin-resistant P388 (P388/VCR) and doxorubicin-resistant P388 (P388/MDR) cells with IC50 (μmol/L) of 0.5, 0.4, 2.0, respectively. CAS No. 135261-89-1. Molecular formula: C13H10N4O3S. Mole weight: 302.31. | |
| BE-12406 A | BE-12406 A is an antitumor antibiotic produced by Streptomyces rutrersensis subsp. castelarensis. It has the activity of inhibiting murine P388 leukemia cells (IC50 is 0.8 μmol/L), and has the same activity against vincristine-doxorubicin resistant strains (P388/VCR) (IC50 is 0.2 μmol/L). It can inhibit the growth of S480 ascites carcinoma in mice. Synonyms: BE 12406A; 6H-Benzo(d)naphtho(1,2-b)pyran-6-one, 12-((6-deoxy-alpha-L-mannopyranosyl)oxy)-1-hydroxy-10-methoxy-8-methyl-. CAS No. 132417-96-0. Molecular formula: C25H24O9. Mole weight: 468.45. | |
| BE-12406 B | BE-12406 B is an antitumor antibiotic produced by Streptomyces rutrersensis subsp. castelarensis. It has the activity of inhibiting murine P388 leukemia cells (IC50 is 7 μmol/L), and has the same activity against vincristine-doxorubicin resistant strains (P388/VCR) (IC50 is 7 μmol/L). It can inhibit the growth of S480 ascites carcinoma in mice. Synonyms: 12-((6-Deoxyhexopyranosyl)oxy)-1,10-dihydroxy-8-methyl-6H-benzo(d)naphtho(1,2-b)pyran-6-one. CAS No. 132417-97-1. Molecular formula: C24H22O9. Mole weight: 454.43. | |
| Desacetyl Vindoline | Precursor to Vindoline during Vincristine biosynthesis. Group: Biochemicals. Alternative Names: (2 β,3 β,4 β, 5α, 12R, 19α)-6, 7-Didehydro-3, 4-dihydroxy-16-methoxy-1-methyl-aspidospermidine-3-carboxylic Acid Methyl Ester; 4-Desacetylvindoline; Deacetylvindoline; NSC 91993. Grades: Highly Purified. CAS No. 3633-92-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Elacridar hydrochloride (GF 120918, P-gp inhibitor, (N-[4-[2- (3, 4-Dihydro-6, 7-dimethoxy-2 (1H) -isoquinolinyl) ethyl]phenyl]-9, 10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide hydrochloride) | P-glycoprotein (P-gp/ABCG1) inhibitor. Blocks P-gp-mediated multidrug resistance (MDR) of the cytotoxic drugs doxorubicin and vincristine in CHRC5 cells. Also inhibits breast cancer resistance protein (BCRP/ABCG2). Orally active. Group: Biochemicals. Grades: Highly Purified. CAS No. 143851-98-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Mps1-IN-3 | MPS1-IN-3 is a selective and potent MPS1 inhibitor with phenotypic consequences similar to those reported for published MPS1 inhibitors such as MPS1-IN-1, MPS1-IN-2, and AZD3146. Treatment with MPS1-IN-3 at 5 μM sensitized all glioblastoma cells to 3 nM of vincristine as measured by cell counts 11 days posttreatment. U251-FM cells were stereotactically injected into the brain of nude mice. Ten days postinjection, 2 mg/kg of MPS1-IN-3 and/or 0.5 mg/kg of vincristine were administered concomitantly by intravenous injections twice per week for 3 weeks. Synonyms: Mps1-IN-3; Mps1 IN3; Mps1-IN3. Grades: >98%. CAS No. 1609584-72-6. Molecular formula: C26H31N7O4S. Mole weight: 537.63. | |
| Mps1-IN-3 hydrochloride | Mps1-IN-3 hydrochloride is a potent and selective Mps1 inhibitor with an IC 50 value of 50 nM. Mps1-IN-3 hydrochloride can inhibit the proliferation of glioblastoma cells, and effectively sensitizes glioblastomas to Vincristine in orthotopic glioblastoma xenograft model [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2989453-29-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12401A. | |
| MS-073 | MS-073 is a Type II DNA topoisomerase inhibitor under the development of Nihon Schering. MS-073 can overcome MDR in vitro and in vivo compare to verapamil. MS-073 at 0.1 mM can almost completely reverse in vitro resistance to vincristine in vincristine-resistant P388 cells. MS-073 can also reverse in vitro vincristine, adriamycin, etoposide, and actinomycin D resistance in adriamycin-resistant human myelogenous leukemia K562 cells. MS-073 reverses MDR through competitively inhibiting drug binding to P-glycoprotein. Treatment for cancer was discontinued. Uses: Cancer. Synonyms: MS-073; MS073; MS 073; CP-162398; CP-162398; CP 162398; CP162398; 1-(Quinolin-5-yloxy)-3-[4-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten)-5-yl]piperazin-1-yl]-2-propanol. Grades: 98%. CAS No. 129716-45-6. Molecular formula: C31H33N3O2. Mole weight: 479.62. | |
| PC-046 | PC-046 is a potent tubulin-binding agent, which was originally identified for development based on selective activity in deleted in pancreas cancer locus 4 (DPC4/SMAD4) deficient tumors. PC-046 has growth inhibitory activity in a variety of tumor types in vitro, and efficacy in SCID mice was shown in human tumor xenografts of MV-4-11 acute myeloid leukemia, MM.1S multiple myeloma, and DU-145 prostate cancer. Pharmacokinetic studies demonstrated relatively high oral bioavailability (71 %) with distribution to both plasma and bone marrow. No myelosuppression was seen in non-tumor bearing SCID mice given a single dose just under the acute lethal dose. The COMPARE algorithm in the NCI-60 cell line panel demonstrated that PC-046 closely correlated to other known tubulin destabilizing agents (correlation coefficients ?0.7 for vincristine and vinblastine). Mechanism of action studies showed cell cycle arrest in metaphase and inhibition of tubulin polymerization. Overall, these studies show that PC-046 is a synthetically-derived, small molecule microtubule destabilizing agent. Advantages over existing microtubule destabilizing agents include ease of synthesis, lack of MDR cross-resistance, good oral bioavailability and the lack of acute myelotoxicity. Synonyms: PC 046; PC046; NSC-756784; 5-(4-methoxyphenyl)-2-(3-(3-methoxyphenyl)pyridin-4-yl)oxazole. Grades: 98%. CAS No. 1202401-59-9. Molecular formula: C22H18N2O3. Mole weight: 358.39. | |
| Phomopsin A | Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis. Phomopsin A is a noncompetitive inhibitor of the binding of radiolabeled vincristine to tubulin [1]. Uses: Scientific research. Group: Natural products. CAS No. 64925-80-0. Pack Sizes: 1 mg. Product ID: HY-N6793. | |
| Piperafizine A | It is a methylated diketopiperazine formed by the condensation of phenylalanine and is produced by many species in the genus Streptomyces. It exhibits little activity in vitro but potentiates vincristine antitumour potency. Synonyms: 3,6-Dibenzylidene-1-methyl-2,5-dioxopiperazine. Grades: >99% by HPLC. CAS No. 130603-59-7. Molecular formula: C19H16N2O2. Mole weight: 304.34. | |
| Piperafizine A (3,6-Dibenzylidene-1-methyl-2,5-dioxopiperazine) | Piperafizine A is a methylated diketopiperazine formed by the condensation of phenylalanine and produced by a number of species in the Streptomyces genus. Piperafizine A exhibits little activity in vitro but has been seen to potentiate vincristine antitumor potency. The mechanism of action has not been characterized. Group: Biochemicals. Alternative Names: 3,6-Dibenzylidene-1-methyl-2,5-dioxopiperazine. Grades: Highly Purified. CAS No. 130603-59-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Rubiginone B2 | Antibiotic with vincristine-cytotoxicity potentiating activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 130548-10-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
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