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Vinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na + channels. The IC 50 value of Vinpocetine on direct IKK inhibition in the cell-free system is 17.17 μM. Vinpocetine is a phosphodiesterase (PDE) inhibitor and inhibits NF-κB -dependent inflammatory responses by directly targeting IκB kinase complex (IKK) , and has been widely used for the treatment of cerebrovascular disorders [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Ethyl apovincaminate. CAS No. 42971-09-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13295.
Vinpocetine
Vinpocetine. Group: Biochemicals. Grades: Purified. CAS No. 42971-09-5. Pack Sizes: 50mg. US Biological Life Sciences.
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Vinpocetine
Vinpocetine - Product ID: NST-10-130. Category: Alkaloids. Alternative Names: Bravinton, Cavinton, Ceractin, Ethyl apovincaminate, Vinpocetine, Vinporal. Purity: 98%. Test method: HPLC. CAS No. 42971-09-5. Pack Sizes: 5g, 10g, 25g, 50g. Appearance: White Powder. Molecular formula: C22H26N2O2. Mole weight: 650.45. Storage: +2 +8 °C.
A calcium/calmodulin-dependent phosphodiesterase 1 (PDE1) inhibitor. Group: Biochemicals. Alternative Names: 3a,16a-Eburnamenine-14-carboxylic Acid Ethyl Ester, 3a,16a-Apovincaminic Acid Ethyl Ester, Ethyl Apovincamin-22-oate, RGH-4405, Cavinton. Grades: Highly Purified. CAS No. 42971-09-5. Pack Sizes: 100mg. US Biological Life Sciences.
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Vinpocetine 99+%
Vinpocetine 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences.
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Vinpocetine 99% Trit
Vinpocetine 99% Trit.
CA, FL & NJ
Vinpocetine Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Vinpocetine Related Compound B
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Vinpocetine Related Compound C
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
10-Methoxy Vinpocetine-d5
10-Methoxy Vinpocetine-d5 is labelled 10-Methoxy Vinpocetine-d5 (E817935) which is an impurity of Vinpocetine (V332500), a semisynthetic derivative of the alkaloid vincamine with vasodilating activity. Vinpocetine (V332500) has been also identified as a novel anti-inflammatory agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C23H23D5N2O3, Molecular Weight: 385.51. US Biological Life Sciences.
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(-)-(14α)-Dihydrovinpocetine-d5
(-)-(14α)-Dihydrovinpocetine-d5 is labelled (-)-Dihydroapovincaminic Acid Ethyl Ester (D448350), a chiral modifier in enantioselective heterogeneous catalytic hydrogenations. It is also structurally related to Vinpocetine (V332500), a Vasodilator (cerebral). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C22H23D5N2O2, Molecular Weight: 357.5. US Biological Life Sciences.
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(+)-(14 β)-Dihydrovinpocetine
(+)-(14 β)-Dihydrovinpocetine is a stereoisomer of (-)-Dihydroapovincaminic Acid Ethyl Ester (D448350), a chiral modifier in enantioselective heterogeneous catalytic hydrogenations. It is also structurally related to Vinpocetine (V332500), a Vasodilator (cerebral). Group: Biochemicals. Grades: Highly Purified. CAS No. 57517-54-1. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C22H28N2O2, Molecular Weight: 352.47. US Biological Life Sciences.
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(+)-(14beta)-Dihydrovinpocetine
An impurity of Vinpocetine. Vinpocetine, isolated from the lesser periwinkle plant, is a derivative of the vinca alkaloid vincamine with an effect of cerebral blood-flow enhancing and neuroprotection. Vinpocetine was approved for the treatment of cerebrovascular disorders and age-related memory impairment in Eastern Europe. Synonyms: (12S,13aS,13bS)-13a-Ethyl-2,3,5,6,12,13,13a,13b-octahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylic Acid Ethyl Ester; (3α,14β,16α)-14,15-Dihydro-eburnamenine-14-carboxylic Acid Ethyl Ester; Ethyl (14β)-14,15-dihydroapovincaminate. CAS No. 57517-54-1. Molecular formula: C22H28N2O2. Mole weight: 352.47.
(+)-(14 β)-Dihydrovinpocetine-d5
(+)-(14 β)-Dihydrovinpocetine-d5 is labelled (+)-(14 β)-Dihydrovinpocetine (D448385) which is a stereoisomer of (-)-Dihydroapovincaminic Acid Ethyl Ester (D448350), a chiral modifier in enantioselective heterogeneous catalytic hydrogenations. It is also structurally related to Vinpocetine (V332500), a Vasodilator (cerebral). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C22H23D5N2O2, Molecular Weight: 357.5. US Biological Life Sciences.
Worldwide
Ethyl (13aS,13bS)-13a-Ethyl-10-methoxy-2,3,5,6,13a,13b-hexahydro-1H-indolo. [3,2,1-de]-pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate. (Vinpocetine Related Compound C).
Ethyl (13aS, 13bS)-13a-Ethyl-10-methoxy-2, 3, 5, 6, 13a, 13b-hexahydro-1H-indolo[3, 2, 1-de]-pyrido[3, 2, 1-ij][1, 5]naphthyridine-12-carboxylate (Vinpocetine Related Compound C). Group: Biochemicals. Alternative Names: (13aS)-Ethyl 13a-Ethyl-8-methoxy-2,3,41,5,6,13a-hexahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C23H28N2O3, Molecular Weight: 380.48. US Biological Life Sciences.
Worldwide
14-Epivincamine
An impurity of Vinpocetine. Vinpocetine, isolated from the lesser periwinkle plant, is a derivative of the vinca alkaloid vincamine with an effect of cerebral blood-flow enhancing and neuroprotection. Vinpocetine was approved for the treatment of cerebrovascular disorders and age-related memory impairment in Eastern Europe. Synonyms: Vinca; Isovincamine; methyl 15-ethyl-17-hydroxy-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraene-17-carboxylate; Methyl(3α,14α,6α)-14-hydroxy-14,15-dihydroeburnamenine-14-carboxylate; Vincamine Impurity I. CAS No. 6835-99-0. Molecular formula: C21H26N2O3. Mole weight: 354.45.
16-Epivincamine
An impurity of Vinpocetine. Vinpocetine, isolated from the lesser periwinkle plant, is a derivative of the vinca alkaloid vincamine with an effect of cerebral blood-flow enhancing and neuroprotection. Vinpocetine was approved for the treatment of cerebrovascular disorders and age-related memory impairment in Eastern Europe. Synonyms: methyl (41S,12S,13aR)-13a-ethyl-12-hydroxy-2,3,41,5,6,12,13,13a-octahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate; Vincamine Impurity J. CAS No. 83508-82-1. Molecular formula: C21H26N2O3. Mole weight: 354.45.
An impurity of Vinpocetine. Vinpocetine, isolated from the lesser periwinkle plant, is a derivative of the vinca alkaloid vincamine with an effect of cerebral blood-flow enhancing and neuroprotection. Vinpocetine was approved for the treatment of cerebrovascular disorders and age-related memory impairment in Eastern Europe. Synonyms: (3α,14β,16α)-14,15-Dihydro-14-hydroxyeburnamenine-14-carboxylic Acid; (+)-Vincaminic Acid; (+)-cis-Vincaminic Acid; cis-Vincaminic Acid; Eburnamenine-14-carboxylic. CAS No. 28152-73-0. Molecular formula: C20H24N2O3. Mole weight: 340.42.
(3R,14R,16R)-Vincamine
An impurity of Vinpocetine. Vinpocetine, isolated from the lesser periwinkle plant, is a derivative of the vinca alkaloid vincamine with an effect of cerebral blood-flow enhancing and neuroprotection. Vinpocetine was approved for the treatment of cerebrovascular disorders and age-related memory impairment in Eastern Europe. Synonyms: methyl (41R,12R,13aR)-13a-ethyl-12-hydroxy-2,3,41,5,6,12,13,13a-octahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate. CAS No. 38990-16-8. Molecular formula: C21H26N2O3. Mole weight: 354.45.
(3R,14S,16S)-Vincamine
An impurity of Vinpocetine. Vinpocetine, isolated from the lesser periwinkle plant, is a derivative of the vinca alkaloid vincamine with an effect of cerebral blood-flow enhancing and neuroprotection. Vinpocetine was approved for the treatment of cerebrovascular disorders and age-related memory impairment in Eastern Europe. Synonyms: (+)-trans-Vincamine; 21-Epivincamine; 3-Epivincamine; 3-Isovincamine; NSC 131616; trans-Vincamine. CAS No. 18374-18-0. Molecular formula: C21H26N2O3. Mole weight: 354.45.
Apovinicaminic acid hydrochloride
An impurity of Vinpocetine. Vinpocetine, isolated from the lesser periwinkle plant, is a derivative of the vinca alkaloid vincamine with an effect of cerebral blood-flow enhancing and neuroprotection. Vinpocetine was approved for the treatment of cerebrovascular disorders and age-related memory impairment in Eastern Europe. Synonyms: 1H-Indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylic acid, 13a-ethyl-2,3,5,6,13a,13b-hexahydro-, hydrochloride (1:1), (13aS,13bS)-; (13aS,13bS)-13a-Ethyl-2,3,5,6,13a,13b-hexahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylic acid hydrochloride; Apovincamin-22-oic acid hydrochloride; (+)-Apovincaminic acid hydrochloride; (+)-cis-Apovincaminic acid hydrochloride; (3α,16α)-Eburnamenine-14-carboxylic acid hydrochloride; cis-Apovincaminic acid hydrochloride; Apovincaminic acid hydrochloride. CAS No. 72296-47-0. Molecular formula: C20H22N2O2.HCl. Mole weight: 358.86.
(+)-cis-10-Methoxyvincamine
An impurity of Vinpocetine. Vinpocetine, isolated from the lesser periwinkle plant, is a derivative of the vinca alkaloid vincamine with an effect of cerebral blood-flow enhancing and neuroprotection. Vinpocetine was approved for the treatment of cerebrovascular disorders and age-related memory impairment in Eastern Europe. Synonyms: methyl (41S,12S,13aS)-13a-ethyl-12-hydroxy-8-methoxy-2,3,41,5,6,12,13,13a-octahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate. CAS No. 57430-34-9. Molecular formula: C22H28N2O4. Mole weight: 384.47.
cis-Apovincamine
cis-Apovincamine. Group: Biochemicals. Alternative Names: (3α,16α)-Eburnamenine-14-carboxylic Acid Methyl Ester; 1H-Indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine, eburnamenine-14-carboxylic acid deriv.; (+)-Apovincamine; (+)-cis-Apovincamine; Methyl (3α,16α)-eburnamenine-14-carboxylate; Vinpocetine Related Compound B; (methyl (13aS,13bS)-13a-ethyl-9-methoxy-2,3,5,6,13a,13b-hexahydro-1H-indolo[3,2,1-de]-pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate. Grades: Highly Purified. CAS No. 4880-92-6. Pack Sizes: 1mg. Molecular Formula: C21H24N2O2, Molecular Weight: 336.43. US Biological Life Sciences.
Worldwide
(+)-cis-Vincaminic Acid Ethyl Ester
(+)-cis-Vincaminic Acid Ethyl Ester. Group: Biochemicals. Alternative Names: (3α,14 β,16α)-14,15-Dihydro-14-hydroxyeburnamenine-14-carboxylic Acid Ethyl Ester; 1H-Indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine, eburnamenine-14-carboxylic Acid Deriv.; (+)-Ethyl vincaminate; Ethyl (+)-cis-Vincaminate; Ethyl Vincaminate; Vincaminic Acid Ethyl Ester; Ethyl (12RS,13aSR,13bSR)-13a-Ethyl-12-hydroxy-2,3,5,6,12,13,13a,13b-octahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate; Vinpocetine Related Compound A. Grades: Highly Purified. CAS No. 40163-56-2. Pack Sizes: 1mg. Molecular Formula: C22H28N2O3, Molecular Weight: 368.47. US Biological Life Sciences.
Worldwide
(-)-Dihydroapovincaminic Acid Ethyl Ester
(-)-Dihydroapovincaminic Acid Ethyl Ester. Group: Biochemicals. Alternative Names: (12R,13aS,13bS)-13a-Ethyl-2,3,5,6,12,13,13a,13b-octahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylic Acid Ethyl Ester; (3α, 14α, 16α)-14, 15-dihydroeburnamenine-14-carboxylic Acid Ethyl Ester; 1H-Indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine, eburnamenine-14-carboxylic Acid deriv.; (-)-(14α)-Dihydrovinpocetine; Ethyl 14,15-Dihydroapovincaminate; (Ethyl (12RS,13aRS,13bRS)-13a-ethyl-2,3,5,6,12,13,13a,13b-octahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate); Vinpocetine Related Compound D. Grades: Highly Purified. CAS No. 57327-92-1. Pack Sizes: 5mg. Molecular Formula: C22H28N2O2, Molecular Weight: 352.47. US Biological Life Sciences.
Worldwide
Ethyl (3S,16R)-apovincaminate
An impurity of Vinpocetine. Vinpocetine, isolated from the lesser periwinkle plant, is a derivative of the vinca alkaloid vincamine with an effect of cerebral blood-flow enhancing and neuroprotection. Vinpocetine was approved for the treatment of cerebrovascular disorders and age-related memory impairment in Eastern Europe. Synonyms: Ethyl (41S,13AR)-13A-ethyl-2,3,41,5,6,13A-hexahydro-1H-indolo[3,2,1-DE]pyrido[3,2,1-IJ][1,5]naphthyridine-12-carboxylate. CAS No. 85647-43-4. Molecular formula: C22H26N2O2. Mole weight: 350.46.
(-)-Ethyl apovincaminate
An impurity of Vinpocetine. Vinpocetine, isolated from the lesser periwinkle plant, is a derivative of the vinca alkaloid vincamine with an effect of cerebral blood-flow enhancing and neuroprotection. Vinpocetine was approved for the treatment of cerebrovascular disorders and age-related memory impairment in Eastern Europe. Synonyms: 1H-Indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylic acid, 13a-ethyl-2,3,5,6,13a,13b-hexahydro-, ethyl ester, (13aR,13bR)-; Eburnamenine-14-carboxylic acid, ethyl ester; (-)-Apovincaminic acid ethyl ester; Ethyl eburnamenine-14-carboxylate; (3R,16R)-Vinpocetine. Grade: ≥95%. CAS No. 42971-12-0. Molecular formula: C22H26N2O2. Mole weight: 350.45.
Ethyl (+)-cis-Epivincaminate
An impurity of Vinpocetine. Vinpocetine, isolated from the lesser periwinkle plant, is a derivative of the vinca alkaloid vincamine with an effect of cerebral blood-flow enhancing and neuroprotection. Vinpocetine was approved for the treatment of cerebrovascular disorders and age-related memory impairment in Eastern Europe. Synonyms: Ethyl (3α,14α,16α)-14,15-Dihydro-14-hydroxy-eburnamenine-14-carboxylate. CAS No. 77549-92-9. Molecular formula: C22H28N2O3. Mole weight: 368.48.
Ethyl trans-apovincaminate
An impurity of Vinpocetine. Vinpocetine, isolated from the lesser periwinkle plant, is a derivative of the vinca alkaloid vincamine with an effect of cerebral blood-flow enhancing and neuroprotection. Vinpocetine was approved for the treatment of cerebrovascular disorders and age-related memory impairment in Eastern Europe. Uses: Neuroprotective agents. Synonyms: (3R,16S)-Vinpocetine; trans-Apovincaminic acid ethyl ester; Eburnamenine-14-carboxylic acid, ethyl ester, (16α)-; Ethyl (16α)-eburnamenine-14-carboxylic acid; Ethyl (3R,16S)-apovincaminate; Ethyl (41R,13aS)-13a-ethyl-2,3,41,5,6,13a-hexahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate. Grade: ≥95%. CAS No. 77549-94-1. Molecular formula: C22H26N2O2. Mole weight: 350.45.
Ethyl vincaminate
An impurity of Vinpocetine. Vinpocetine, isolated from the lesser periwinkle plant, is a derivative of the vinca alkaloid vincamine with an effect of cerebral blood-flow enhancing and neuroprotection. Vinpocetine was approved for the treatment of cerebrovascular disorders and age-related memory impairment in Eastern Europe. Synonyms: (+)-Vincaminic acid ethyl ester; (3α,14β,16α)-14,15-Dihydro-14-hydroxyeburnamenine-14-carboxylic Acid Ethyl Ester; Vinpocetine USP Related Compound A. CAS No. 40163-56-2. Molecular formula: C22H28N2O3. Mole weight: 368.47.
Ethyl vincaminate N-oxide
An impurity of Vinpocetine. Vinpocetine, isolated from the lesser periwinkle plant, is a derivative of the vinca alkaloid vincamine with an effect of cerebral blood-flow enhancing and neuroprotection. Vinpocetine was approved for the treatment of cerebrovascular disorders and age-related memory impairment in Eastern Europe. Synonyms: Eburnamenine-14-carboxylic acid, 14,15-dihydro-14-hydroxy-, ethyl ester, 4-oxide, (3-alpha,14-beta,16-alpha)-; (41S,12S,13aS)-12-(ethoxycarbonyl)-13a-ethyl-12-hydroxy-2,3,41,5,6,12,13,13a-octahydroindolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine 4(1H)-oxide. CAS No. 52341-36-3. Molecular formula: C22H28N2O4. Mole weight: 384.47.
Vinpocetin
Vinpocetin. Group: Biochemicals. Grades: Highly Purified. CAS No. 42971-09-5. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C22H26N2O2. US Biological Life Sciences.
Worldwide
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