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Vorapaxar (SCH 530348), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist ( K i =8.1 nM). Vorapaxar (SCH 530348) inhibits thrombin receptor-activating peptide (TRAP)-induced platelet aggregation in a dose-dependent manner [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH 530348. CAS No. 618385-01-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10119.
Vorapaxar-[d5]
One of the isotopic labelled form of Vorapaxar, which has been found to be an antiplatelet agent and could be potentially effective against atherothrombosis. Synonyms: (1,1,2,2,2-D5)ethyl N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-1-methyl-3-oxo-dodecahydronaphtho[2,3-c]furan-6-yl]carbamate. Grade: >98%. Molecular formula: C29H28D5FN2O4. Mole weight: 497.61.
An impurity of Vorapaxar. Vorapaxar, also known as SCH 530348, is a thrombin receptor (protease-activated receptor, PAR-1) antagonist based on the natural product himbacine. Synonyms: Phosphonic acid, [[5-(3-fluorophenyl)-2-pyridinyl]methyl]-, diethyl ester; [[5-(3-Fluorophenyl)-2-pyridinyl]methyl]phosphonic acid diethyl ester; Vorapaxar Impurity B. Grade: 97%. CAS No. 380894-77-9. Molecular formula: C16H19FNO3P. Mole weight: 323.30.
An impurity of Vorapaxar. Vorapaxar, also known as SCH 530348, is a thrombin receptor (protease-activated receptor, PAR-1) antagonist based on the natural product himbacine. Synonyms: (6S)-Vorapaxar; Vorapaxar Impurity G. Grade: 99%. CAS No. 618385-10-7. Molecular formula: C29H33FN2O4. Mole weight: 492.58.
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