Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| ZIP | ZIP. Group: Biochemicals. Grades: Purified. CAS No. 863987-12-6. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| ZIP | ZIP is a cell-permeable inhibitor of protein kinase Mζ (PKMζ), which is a constitutively active and atypical PKC isozyme involved in LTP maintenance. ZIP selectively blocks PKMζ-induced synaptic potentiation in hippocampal slices in vitro. ZIP reverses late-phase LTP (IC50 = 1 - 2.5 μM) and produces persistent loss of 1-day-old spatial memory following central administration in vivo. Synonyms: ZIP; FLJ36473; DAPK3, active, GST tagged human; PKC Zeta Pseudosubstrate Inhibitory peptide; Protein kinase Cζ pseudosubstrate, myristoyl trifluoroacetate salt; N-(1-Oxotetradecyl)-L-seryl-L-isoleucyl-L-tyrosyl-L-arginyl-L-arginylglycyl-L-alanyl-L-arginyl-L-arginyl-L-tryptophyl-L-arginyl-L-lysyl-L-leucine. CAS No. 863987-12-6. Molecular formula: C90H154N30O17. Mole weight: 1928.37. |  |
| ZIP | ZIP is a selective peptide inhibitor of PKM&zeta. ZIP injections can block the impairment in morphine conditioned place preference induced [1]. Uses: Scientific research. Group: Peptides. CAS No. 863987-12-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1284. |  |
| ZIP acetate | ZIP acetate is a cell-permeable inhibitor of protein kinase Mζ (PKMζ), which is a constitutively active and atypical PKC isozyme involved in LTP maintenance. ZIP selectively blocks PKMζ-induced synaptic potentiation in hippocampal slices in vitro. ZIP reverses late-phase LTP (IC50 = 1-2.5 μM) and produces persistent loss of 1-day-old spatial memory following central administration in vivo. Synonyms: myristoyl-Arg-Leu-Tyr-Arg-Lys-Arg-Ile-Trp-Arg-Ser-Ala-Gly-Arg-OH.CH3CO2H; N-myristoyl-L-arginyl-L-leucyl-L-tyrosyl-L-arginyl-L-lysyl-L-arginyl-L-isoleucyl-L-tryptophyl-L-arginyl-L-seryl-L-alanyl-glycyl-L-arginine acetic acid; N-(1-Oxotetradecyl)-L-seryl-L-isoleucyl-L-tyrosyl-L-arginyl-L-arginylglycyl-L-alanyl-L-arginyl-L-arginyl-L-tryptophyl-L-arginyl-L-lysyl-L-leucine acetate; Peptide ZIP acetate; z-Pseudosubstrate inhibitory peptide acetate. Grades: ≥94%. Molecular formula: C92H158N30O19. Mole weight: 1988.43. | |
| Zipalertinib | Zipalertinib, also known as TAS6417, CLN-081, is a Novel EGFR Inhibitor Targeting Exon 20 Insertion Mutations. TAS6417 inhibited EGFR with various exon 20 insertion mutations more potently than it inhibited the WT. TAS6417 inhibited EGFR phosphorylation and downstream molecules in NSCLC cell lines expressing EGFR exon 20 insertions, resulting in caspase activation. These characteristics led to marked tumor regression in vivo in both a genetically engineered model and in a patient-derived xenograft model. Furthermore, TAS6417 provided a survival benefit with good tolerability in a lung orthotopic implantation mouse model. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TAS6417; TAS-6417; TAS 6417; CLN-081; CLN081; CLN081; Zipalertinib. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1661854-97-2. Molecular formula: C23H20N6O. Mole weight: 396.45. Purity: >98%. IUPACName: (S)-N-(4-amino-6-methyl-5-(quinolin-3-yl)-8,9-dihydropyrimido[5,4-b]indolizin-8-yl)acrylamide. Canonical SMILES: NC1=C2C(N3C(C(C)=C[C@@H](C3)NC(C=C)=O)=C2C4=CC5=CC=CC=C5N=C4)=NC=N1. Product ID: ACM1661854972. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Zipalertinib | Zipalertinib (TAS6417; CLN-081) is a highly effective, orally active and pan-mutation-selective EGFR tyrosine kinase inhibitor with a unique scaffold fitting into the ATP-binding site of the EGFR hinge region, with IC 50 values ranging from 1.1-8.0 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAS6417; CLN-081. CAS No. 1661854-97-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112299. | |
| ZIP (Biotin) | Biotinylated peptide for ZIP. Group: Biochemicals. Grades: Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| ZIP, Biotinylated | ZIP, Biotinylated is a ZIP covalently attached with a biotin. It potently binds to avidins (Kd = 4 x 10-14 M), which mediates detection of ZIP in biochemical assays. Synonyms: z-Pseudosubstrate inhibitory peptide, biotinylated. Grades: >98%. Molecular formula: C100H168N32O19S. Mole weight: 2154.69. | |
| Ziprasidone | Ziprasidone (CP-88059), an orally active antipsychotic agent, is a combined 5-HT and dopamine receptor antagonist [1]. Ziprasidone mesylate trihydrate has affinities for Rat D 2 ( K i =4.8 nM), 5-HT 2A ( K i =0.42 nM) and 5-HT 1A ( K i =3.4 nM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-88059. CAS No. 146939-27-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14542. | |
| Ziprasidone | Ziprasidone. Group: Biochemicals. Grades: Highly Purified. CAS No. 146939-27-7. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C21H21ClN4OS. US Biological Life Sciences. | Worldwide |
| Ziprasidone | Ziprasidone is a combined 5-HT (serotonin) and dopamine receptor antagonist like other atypical antipsychotic agents. Ziprasidone targets dopamine neurotransmission at dopamine D2 receptors which is significant for the positive symptoms of schizophrenia. Synonyms: 5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one 5-(2-(4-(3-benzisothiazolyl)piperazinyl)ethyl)-6-chloro-1,3-dihydro-2H-indol-2-one CP 88059 CP 88059-01 CP-88,059 CP-88,059-01 CP-88,059-1 Geodon ziprasidone ziprasidone. CAS No. 146939-27-7. Molecular formula: C21H21ClN4OS. Mole weight: 412.94. | |
| Ziprasidone Amino Acid Sodium Salt (Ziprasidone Impurity C) | Ziprasidone impurity C. Group: Biochemicals. Alternative Names: [2-Amino-5-[2-[4-(1,2-benzisothiazol-3-yl)piperazin-1-yl]ethyl]-4-chlorophenyl]acetic Acid Sodium Salt; 2-Amino-5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-4-chlorobenzeneacetic Acid; Ziprasidone Impurity C. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ziprasidone-D8 | Ziprasidone-D8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1126745-58-1. Molecular formula: C21H13D8ClN4OS. Mole weight: 420.99. Catalog: APB1126745581. |  |
| Ziprasidone-d8 (5-[2-[4-(1,2-Benzisothiazol-3yl)-1-piperazinyl-d8]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one) | Labelled Ziprasidone, which is used as an antipsychotic. Group: Biochemicals. Alternative Names: 5-[2-[4-(1,2-Benzisothiazol-3yl)-1-piperazinyl-d8]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one. Grades: Highly Purified. CAS No. 146939-27-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ziprasidone Deschloro Impurity | One of the impurities of Ziprasidone, which is a 5-HT as well as dopamine receptor antagonist and could be effective as an antipsychotic agent. CAS No. 118305-72-9. Molecular formula: C21H22N4OS. Mole weight: 378.5. | |
| Ziprasidone HCl | The hydrochloride salt form of Ziprasidone which is an antagonism of both serotonin and dopamine receptor and could be effective against schizophrenia. Uses: The hydrochloride salt form of ziprasidone which is an antagonism of both serotonin and dopamine receptor and could be effective against schizophrenia. Synonyms: 5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one hydrochloride;5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one hydrochloride;5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethy. Grades: 95%. CAS No. 122883-93-6. Molecular formula: C21H21ClN4OS.HCl. Mole weight: 449.40. | |
| Ziprasidone hydrochloride | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Ziprasidone hydrochloride | Ziprasidone hydrochloride. Group: Biochemicals. Alternative Names: 5-[2-[4-(1,2-Benzisothiazol-3yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one. Grades: Highly Purified. CAS No. 122883-93-6. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C21H21ClN4OS·HCl. US Biological Life Sciences. | Worldwide |
| Ziprasidone hydrochloride monohydrate | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopyapi standardseuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: Ziprasidone Hydrochloride Monohydrate. | |
| Ziprasidone hydrochloride monohydrate | Ziprasidone (CP-88059) hydrochloride monohydrate is an orally active combined 5-HT and dopamine receptor antagonist [1]. Ziprasidone hydrochloride monohydrate has affinities for Rat D 2 ( K i =4.8 nM), 5-HT 2A ( K i =0.42 nM) and 5-HT 1A ( K i =3.4 nM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP 88059 hydrochloride monohydrate. CAS No. 138982-67-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-17407. | |
| Ziprasidone hydrochloride monohydrate | Ziprasidone hydrochloride monohydrate. Group: Biochemicals. Alternative Names: 5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one hydrochloride monohydrate, CP-88059-1; Geodon hydrochloride hydrate. Grades: Highly Purified. CAS No. 138982-67-9. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C21H24Cl2N4O2S. US Biological Life Sciences. | Worldwide |
| Ziprasidone Hydrochloride Monohydrate | The hydrochloride monohydrate salt form of Ziprasidone, a benzothiazol derivative, has been found to be a 5HT2A and D2 receptor antagonist that could be used against schizophrenia and other sorts of psychotic. pKi: 9.38 and 8.32 for 5-HT2A and D2 receptor. Uses: The hydrochloride monohydrate salt form of ziprasidone has been found to be a 5ht2a and d2 receptor antagonist that could be used against schizophrenia and other sorts of psychotic. Synonyms: ZIPRASIDONE HCL;ZIPRASIDONE HYDROCHLORIDE;ZIPRASIDONE HYDROCHLORIDE MONOHYDRATE;CP-88059-1;5-[2-[4-(1,2-BENZISOTHIAZOL-3YL)-1-PIPERAZINYL]ETHYL]-6-CHLORO-1,3-DIHYDRO-2H-INDOL-2-ONE, HYDROCHLORIDE MONOHYDRATE;5-[2-[4-(1,2-benzisothiazol-3yl)-1-piperazinyl. Grades: >99 %. CAS No. 138982-67-9. Molecular formula: C21H21ClN4OS.ClH.H2O. Mole weight: 467.419. | |
| Ziprasidone, Hydrochloride Monohydrate (5-[2-[4-(1,2-Benzisothiazol-3yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one, Hydrochloride Monohydrate, CP-88059-1) | Used as an antipsychotic. Group: Biochemicals. Alternative Names: 5-[2-[4-(1,2-Benzisothiazol-3yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one, Hydrochloride Monohydrate, CP-88059-1. Grades: Highly Purified. CAS No. 138982-67-9. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| Ziprasidone Impurity | One of the impurities of Ziprasidone, which is a 5-HT as well as dopamine receptor antagonist and could be effective as an antipsychotic agent. Synonyms: 6-Chloro-5-(2-chloro-1-hydroxyethyl)-1,3-dihydro-2H-indol-2-one. CAS No. 884305-06-0. Molecular formula: C10H9Cl2NO2. Mole weight: 246.09. | |
| Ziprasidone Impurity B | One of the impurities of Ziprasidone, which is a 5-HT as well as dopamine receptor antagonist and could be effective as an antipsychotic agent. Synonyms: 5-[2-[4-(1,2-Benzisothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1H-indole-2,3-dione. CAS No. 1159977-56-6. Molecular formula: C21H19ClN4O2S. Mole weight: 426.93. | |
| Ziprasidone Impurity E | One of the impurities of Ziprasidone, which is a 5-HT as well as dopamine receptor antagonist and could be effective as an antipsychotic agent. Synonyms: 3-(1,2-Benzisothiazol-3-yl)-5-[2-[4-(1,2-benzisothiazol-3yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one; Ziprasidone EP Impurity E. CAS No. 1159977-04-4. Molecular formula: C28H24ClN5OS2. Mole weight: 546.12. | |
| Ziprasidone N-Oxide | One of the impurities of Ziprasidone, which is a 5-HT as well as dopamine receptor antagonist and could be effective as an antipsychotic agent. Synonyms: 5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-oxido-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one. CAS No. 188797-76-4. Molecular formula: C21H21ClN4O2S. Mole weight: 428.94. | |
| Ziprasidone Related Compound B | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Ziprasidone Related Compound C | One of the impurities of Ziprasidone, which is a 5-HT as well as dopamine receptor antagonist and could be effective as an antipsychotic agent. Synonyms: (5,5'-Bis(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6,6'-dichloro-3-hydroxy-3,3'-biindoline-2,2'-dione); Ziprasidone EP Impurity D. CAS No. 1303996-68-0. Molecular formula: C42H40Cl2N8O3S2. Mole weight: 839.87. | |
| Ziprasidone Related Compound C | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Ziprasidone Related Compound D | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Ziprasidone Ring-opened Impurity (Impurity C) | One of the impurities of Ziprasidone, which is a 5-HT as well as dopamine receptor antagonist and could be effective as an antipsychotic agent. Synonyms: 2-[2-Amino-5-[2-[4-(1,2-benzisothiazol-3-yl)piperazin-1-yl]ethyl]-4-chlorophenyl]acetic acid. CAS No. 1159977-64-6. Molecular formula: C21H23ClN4O2S. Mole weight: 430.96. | |
| Ziprasidone Sulfone Hydrochloride | A metabolite of Ziprasidone. Group: Biochemicals. Alternative Names: 6-Chloro-5-[2-[4-(1,1-dioxido-1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-1,3-dihydro-. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Ziprasidone Sulfoxide | A metabolite of Ziprasidone. Group: Biochemicals. Alternative Names: 6-Chloro-1,3-dihydro-5-[2-[4-(1-oxido-1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-. Grades: Highly Purified. CAS No. 188797-80-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Ziprasidone Sulfoxide | The Sulfoxide derived form of Ziprasidone, which is a 5-HT as well as dopamine receptor antagonist and could be effective as an antipsychotic agent. Synonyms: 6-Chloro-1,3-dihydro-5-[2-[4-(1-oxido-1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-2H- indol-2-one. CAS No. 188797-80-0. Molecular formula: C21H21ClN4O2S. Mole weight: 428.94. | |
| ZIP (Scrambled) | ZIP (Scrambled). Group: Biochemicals. Grades: Purified. CAS No. 908012-18-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| ZIP (Scrambled) | ZIP (Scrambled) is a scrambled control peptide for ZIP. Synonyms: z-Pseudosubstrate inhibitory peptide (scrambled); myristoyl-Arg-Leu-Tyr-Arg-Lys-Arg-Ile-Trp-Arg-Ser-Ala-Gly-Arg-OH; N-myristoyl-L-arginyl-L-leucyl-L-tyrosyl-L-arginyl-L-lysyl-L-arginyl-L-isoleucyl-L-tryptophyl-L-arginyl-L-seryl-L-alanyl-glycyl-L-arginine. Grades: >98%. CAS No. 908012-18-0. Molecular formula: C90H154N30O17. Mole weight: 1928.38. | |
| ZIP (Scrambled) acetate | ZIP (Scrambled) TFA, a scrambled peptide, can be used as a negative control for zeta inhibitory peptide (ZIP). Synonyms: myristoyl-Arg-Leu-Tyr-Arg-Lys-Arg-Ile-Trp-Arg-Ser-Ala-Gly-Arg-OH.CH3CO2H; N-myristoyl-L-arginyl-L-leucyl-L-tyrosyl-L-arginyl-L-lysyl-L-arginyl-L-isoleucyl-L-tryptophyl-L-arginyl-L-seryl-L-alanyl-glycyl-L-arginine acetic acid. Grades: ≥95%. CAS No. 2763584-14-9. Molecular formula: C92H158N30O19. Mole weight: 1988.43. | |
| 3-(1-Piperazinyl)-1,2-benzisothiazole Hydrochloride (1:1). (Ziprasidone Related Compound A) | 3-(1-Piperazinyl)-1,2-benzisothiazole Hydrochloride (1:1)(Ziprasidone Related Compound A). Group: Biochemicals. Alternative Names: 3-(1-Piperazinyl)-1,2-benzisothiazole Monohydrochloride; 3-Piperazin-1-yl-benzo[d]isothiazole Hydrochloride; 3-Piperazinyl-1,2-benzisothiazole Hydrochloride; 4-(1,2-Benzisothiazol-3-yl)piperazine Hydrochloride; (3-(Piperazin-1-yl)benzo[d]isothiazole Monohydrochloride. Grades: Highly Purified. CAS No. 87691-88-1. Pack Sizes: 2.5mg. Molecular Formula: C11H14ClN3S, Molecular Weight: 255.77. US Biological Life Sciences. | Worldwide |
| Anti-Zip Kinase antibody produced in rabbit | affinity isolated antibody, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| 10074-G5 | 10074-G5, similarly to 10058-F4, is an inhibitor of c-Myc-Maxdimerization (IC50 = 146 μM) that suppresses its transcriptional activity. 10074-G5 binds to and distorts the bHLH-ZIP domain of c-Myc (Kd = 2.8 μM), thus preventing C-Myc specific DNA binding and target genes regulation. Synonyms: 10074 G5; Biphenyl-2-yl-(7-nitrobenzo[1,2,5]oxadiazol-4-yl)amine; 10074G5. CAS No. 413611-93-5. Molecular formula: C18H12N4O3. Mole weight: 332.31. | |
| 1- (1-Oxidobenzo [d]isothiazol-3-yl) piperazine 1-Oxide Hydrochloride | 1- (1-Oxidobenzo [d]isothiazol-3-yl) piperazine 1-Oxide Hydrochloride is an intermediate in the synthesis of Ziprasidone related compounds. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 50mg. Molecular Formula: C11H14ClN3O2S. US Biological Life Sciences. | Worldwide |
| 2-[5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-4-chloro-2-nitrophenyl]-propanedioic Acid 1,3-Dimethyl Ester | Intermediate in the synthesis of the antipsychotic agent Ziprasidone. Group: Biochemicals. Alternative Names: [5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-4-chloro-2-nitrophenyl]-propanedioic Acid Dimethyl Ester. Grades: Highly Purified. CAS No. 160384-39-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 3-(1-Piperazinyl)-1,2-benzisothiazole | A reagent used to synthesize Ziprasidione. Group: Biochemicals. Alternative Names: 3-(Piperazin-1-yl)benzoisothiazole; N- (3-Benzisothiazolyl) piperazine; 1-(1,2-Benzisothiazol-3-yl)piperazine. Grades: Highly Purified. CAS No. 87691-87-0. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| 3-(1-Piperazinyl)-1,2-benzisothiazole 1-Oxide | 3-(1-Piperazinyl)-1,2-benzisothiazole 1-Oxide is an intermediate in synthesizing Ziprasidone Sulfoxide (), a metabolite of Ziprasidone (Z485000). Group: Biochemicals. Grades: Highly Purified. CAS No. 128396-56-5. Pack Sizes: 25mg, 50mg. Molecular Formula: C11H13N3OS. US Biological Life Sciences. | Worldwide |
| 3-(1-Piperazinyl-d8)-1,2-benzisothiazole | 3-(1-Piperazinyl-d8)-1,2-benzisothiazole is the labeled analogue of 3-(1-Piperazinyl)-1,2-benzisothiazole (P480600), a reagent used to synthesize Ziprasidone(Z485000), a combined serotonin (5HT2) and dopamine (D2) receptor antagonist. Used as an antipsychotic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C11H5D8N3S, Molecular Weight: 227.36. US Biological Life Sciences. | Worldwide |
| 3-[4-[2-(2,5-Dichloro-4-nitrophenyl)ethenyl]-1-piperazinyl]-1,2-benzisothiazole | Intermediate in the synthesis of the antipsychotic agent Ziprasidone. Group: Biochemicals. Grades: Highly Purified. CAS No. 160384-37-2. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 3-[4-[2-(2,5-Dichloro-4-nitrophenyl)ethyl]-1-piperazinyl]-1,2-benzisothiazole | Intermediate in the synthesis of the antipsychotic agent Ziprasidone. Group: Biochemicals. Grades: Highly Purified. CAS No. 160384-38-3. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| (3-(Benzo[d]isothiazol-3-yl)-5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one). . | (3-(Benzo[d]isothiazol-3-yl)-5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one). Group: Biochemicals. Alternative Names: Ziprasidone Related Compound D. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C28H24ClN5OS2, Molecular Weight: 546.11. US Biological Life Sciences. | Worldwide |
| 5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-4-chloro-2-nitro-benzeneacetic Acid | Ziprasidone derivative. Group: Biochemicals. Alternative Names: [2-Nitro-5-[2-[4-(1,2-benzisothiazol-3-yl)piperazin-1-yl]ethyl]-4-chlorophenyl]acetic Acid. Grades: Highly Purified. CAS No. 160384-40-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl-4-chloro-2-nitrophenol | Impurity in the synthesis of the antipsychotic agent Ziprasidone. Group: Biochemicals. Alternative Names: 3-[4-[2-(2-Chloro-5-hydroxy-4-nitrophenyl)ethyl]-1-piperazinyl]-1,2-Benzisothiazole. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| (5-(2-(4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindoline-2,3-dione). | (5-(2-(4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindoline-2,3-dione). Group: Biochemicals. Alternative Names: Ziprasidone Related Compound B. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C21H19ClN4O2S, Molecular Weight: 426.92. US Biological Life Sciences. | Worldwide |
| (5,5-Bis(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6,6-dichloro-3-hydroxy-3,3-biindoline-2,2-dione). | (5,5-Bis(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6,6-dichloro-3-hydroxy-3,3-biindoline-2,2-dione). Group: Biochemicals. Alternative Names: Ziprasidone Related Compound C. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C42H40Cl2N8O3S2, Molecular Weight: 839.85. US Biological Life Sciences. | Worldwide |
| CEP-1347 | CEP-1347 is an inhibitor of the JNK/SAPK pathway with neuroprotective effects. CEP-1347 blocks JNK1 activation induced by members of the mixed lineage kinase (MLK) family (MLK3, MLK2, MLK1, dual leucine zipper kinase, and leucine zipper kinase). As an inhibitor of MDM4 , CEP-1347 can more effectively inhibit the growth of glioma cells expressing wild-type p53 [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KT7515. CAS No. 156177-65-0. Pack Sizes: 1 mg. Product ID: HY-10412. | |
| Diclofenac potassium | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardsapi standardseuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: K-Fenak, CGP 45840B, K-fenak, Acetic acid, [o-(2,6-dichloroanilino)phenyl]-, monopotassium salt (8CI),Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, potassium salt (1:1), Diclofenac potassium, ProSorb, Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, monopotassium salt (9CI), Caflam, Cambia, Cataflam, Potassium diclofenac, Zipsor. | |
| HPPE | HPPE (compound 236) is an orally active, potential Bach1 inhibitor. Bach1 is a transcription factor of the cap'n'collar type alkaline region leucine zipper factor family (CNC-bZip) that regulates mitochondrial metabolism and reduces glucose utilization. HPPE can be used for research in psoriasis, multiple sclerosis, and COPD [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bach1-IN-1. CAS No. 1325721-55-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-153040. | |
| HS 38 | HS 38 is an ATP-competitive inhibitor of DAPK (IC50 = 200 nM) and ZIPK (Kd = 280 nM). It also inhibits PIM3 kinase (IC50 = 200 nM) with no significant effect on Src or Abl kinases. HS 38 regulates programmed cell death and phosphorylation of non-muscle and smooth muscle myosin. Synonyms: HS 38; HS38; HS-38; 2-[[1-(3-Chlorophenyl)-4,5-dihydro-4-oxo-1H-pyrazolo[3,4-d]pyrimidin-6-yl]thio]propanamide. Grades: ≥98% by HPLC. CAS No. 1030203-81-6. Molecular formula: C14H12CIN5O2S. Mole weight: 349.8. | |
| OTSSP167 | OTSSP167, also known as OTS167, is an orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity. Upon administration, OTS167 binds to MELK, which prevents both MELK phosphorylation and activation; thus inhibiting the phosphorylation of downstream MELK substrates. This may lead to an inhibition of both cell proliferation and survival in MELK-expressing tumor cells. MELK, a serine/threonine kinase, is involved in cancer cell survival, invasiveness and cancer-stem cell formation and maintenance; it is highly upregulated in various types of cancer cells and absent in normal, healthy cells. Synonyms: 1- (6- (3, 5-dichloro-4-hydroxyphenyl) -4- ( ( (1r, 4r) -4- ( (dimethylamino) methyl) cyclohexyl) amino) -1, 5-naphthyridin-3-yl) ethanone; OTSSP167 free base; OTSSP 167; OTSSP-167; OTS167; OTS-167; OTS 167. Grades: 0.98. CAS No. 1431697-89-0. Molecular formula: C25H28Cl2N4O2. Mole weight: 487.425. | |
| OTSSP167 hydrochloride | OTSSP167 is a potent inhibitor of Maternal embryonic leucine zipper kinase (MELK) which regulates neural stem cell selfrenewal through control of the cell cycle. Synonyms: 4-[7-acetyl-8-[[4-[ (dimethylamino) methyl]cyclohexyl]amino]-1H-1, 5-naphthyridin-2-ylidene]-2, 6-dichlorocyclohexa-2, 5-dien-1-one hydrochloride; OTSSP167 (hydrochloride); UNII-65P731R507; 65P731R507; OTSSP167 HCl; OTS-167 monohydrochloride; HY-15512A; AKOS025117447. CAS No. 1431698-10-0. Molecular formula: C25H29Cl3N4O2. Mole weight: 523.9. | |
| PKC ζ pseudosubstrate | PKC ζ pseudosubstrate, a synthetic peptide, is an inhibitor of protein kinase C (PKC) ζ that attached to cell permeabilisation Antennapedia domain vector peptide. Synonyms: Myristolated PKC Zeta, Pseudosubstrate (ZIP); Myr-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu-OH. Molecular formula: C208H336N74O44S3. Mole weight: 4673.59. | |
| RTA-408 | RTA-408 is a member of the synthetic oleanane triterpenoid class of compounds and an activator of nuclear factor erythroid 2 [NF-E2]-related factor 2 (Nrf2, Nfe2l2), with potential chemopreventive activity. Upon administration, RTA 408 activates the cytoprotective transcription factor Nrf2. In turn, Nrf2 translocates to the nucleus, dimerizes with a small Maf protein (sMaf), and binds to the antioxidant response element (ARE). This induces the expression of a number of cytoprotective genes, including NAD(P)H quinone oxidoreductase 1 (NQO1), sulfiredoxin 1 (Srxn1), heme oxygenase-1 (HO1, HMOX1), superoxide dismutase 1 (SOD1), gamma-glutamylcysteine synthetase (gamma-GCS), thioredoxin reductase-1 (TXNRD1), glutathione S-transferase (GST), glutamate-cysteine ligase catalytic subunit (Gclc) and glutamate-cysteine ligase regulatory subunit (Gclm), and increases the synthesis of the antioxidant glutathione (GSH). Nrf2, a leucine zipper transcription factor, plays a key role in the maintenance of redox balance and cytoprotection against oxidative stress. Synonyms: RTA408; RTA408; RTA-408. Omaveloxolone; Propanamide, N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoro-. Grades: >98%. CAS No. 1474034-05-3. Molecular formula: C33H44F2N2O3. Mole weight: 554.723. | |
| TAS6417 | TAS6417 is a novel EGFR inhibitor that targets EGFR exon 20 insertion mutations while sparing wild-type (WT) EGFR. TAS6417 inhibited EGFR phosphorylation and downstream molecules in NSCLC cell lines expressing EGFR exon 20 insertions, resulting in caspase activation. Synonyms: CLN-081; TPC-064; TAS 6417; TAS-6417; Zipalertinib. CAS No. 1661854-97-2. Molecular formula: C23H20N6O. Mole weight: 396.44. | |
Our database is helping our users find suppliers everyday.
