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| Product | Description | |
|---|---|---|
| ZIP | ZIP. Group: Biochemicals. Grades: Purified. CAS No. 863987-12-6. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| ZIP | ZIP is a cell-permeable inhibitor of protein kinase Mζ (PKMζ), which is a constitutively active and atypical PKC isozyme involved in LTP maintenance. ZIP selectively blocks PKMζ-induced synaptic potentiation in hippocampal slices in vitro. ZIP reverses late-phase LTP (IC50 = 1 - 2.5 μM) and produces persistent loss of 1-day-old spatial memory following central administration in vivo. Synonyms: ZIP; FLJ36473; DAPK3, active, GST tagged human; PKC Zeta Pseudosubstrate Inhibitory peptide; Protein kinase Cζ pseudosubstrate, myristoyl trifluoroacetate salt; N-(1-Oxotetradecyl)-L-seryl-L-isoleucyl-L-tyrosyl-L-arginyl-L-arginylglycyl-L-alanyl-L-arginyl-L-arginyl-L-tryptophyl-L-arginyl-L-lysyl-L-leucine. CAS No. 863987-12-6. Molecular formula: C90H154N30O17. Mole weight: 1928.37. |  |
| ZIP | ZIP is a selective peptide inhibitor of PKM&zeta. ZIP injections can block the impairment in morphine conditioned place preference induced [1]. Uses: Scientific research. Group: Peptides. CAS No. 863987-12-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1284. |  |
| ZIP acetate | ZIP acetate is a cell-permeable inhibitor of protein kinase Mζ (PKMζ), which is a constitutively active and atypical PKC isozyme involved in LTP maintenance. ZIP selectively blocks PKMζ-induced synaptic potentiation in hippocampal slices in vitro. ZIP reverses late-phase LTP (IC50 = 1-2.5 μM) and produces persistent loss of 1-day-old spatial memory following central administration in vivo. Synonyms: myristoyl-Arg-Leu-Tyr-Arg-Lys-Arg-Ile-Trp-Arg-Ser-Ala-Gly-Arg-OH.CH3CO2H; N-myristoyl-L-arginyl-L-leucyl-L-tyrosyl-L-arginyl-L-lysyl-L-arginyl-L-isoleucyl-L-tryptophyl-L-arginyl-L-seryl-L-alanyl-glycyl-L-arginine acetic acid; N-(1-Oxotetradecyl)-L-seryl-L-isoleucyl-L-tyrosyl-L-arginyl-L-arginylglycyl-L-alanyl-L-arginyl-L-arginyl-L-tryptophyl-L-arginyl-L-lysyl-L-leucine acetate; Peptide ZIP acetate; z-Pseudosubstrate inhibitory peptide acetate. Grade: ≥94%. Molecular formula: C92H158N30O19. Mole weight: 1988.43. | |
| Zipalertinib | Zipalertinib, also known as TAS6417, CLN-081, is a Novel EGFR Inhibitor Targeting Exon 20 Insertion Mutations. TAS6417 inhibited EGFR with various exon 20 insertion mutations more potently than it inhibited the WT. TAS6417 inhibited EGFR phosphorylation and downstream molecules in NSCLC cell lines expressing EGFR exon 20 insertions, resulting in caspase activation. These characteristics led to marked tumor regression in vivo in both a genetically engineered model and in a patient-derived xenograft model. Furthermore, TAS6417 provided a survival benefit with good tolerability in a lung orthotopic implantation mouse model. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TAS6417; TAS-6417; TAS 6417; CLN-081; CLN081; CLN081; Zipalertinib. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1661854-97-2. Molecular formula: C23H20N6O. Mole weight: 396.45. Purity: >98%. IUPACName: (S)-N-(4-amino-6-methyl-5-(quinolin-3-yl)-8,9-dihydropyrimido[5,4-b]indolizin-8-yl)acrylamide. Canonical SMILES: NC1=C2C(N3C(C(C)=C[C@@H](C3)NC(C=C)=O)=C2C4=CC5=CC=CC=C5N=C4)=NC=N1. Product ID: ACM1661854972. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Zipalertinib | Zipalertinib (TAS6417; CLN-081) is a highly effective, orally active and pan-mutation-selective EGFR tyrosine kinase inhibitor with a unique scaffold fitting into the ATP-binding site of the EGFR hinge region, with IC 50 values ranging from 1.1-8.0 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAS6417; CLN-081. CAS No. 1661854-97-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112299. | |
| ZIP (Biotin) | Biotinylated peptide for ZIP. Group: Biochemicals. Grades: Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| ZIP, Biotinylated | ZIP, Biotinylated is a ZIP covalently attached with a biotin. It potently binds to avidins (Kd = 4 x 10-14 M), which mediates detection of ZIP in biochemical assays. Synonyms: z-Pseudosubstrate inhibitory peptide, biotinylated. Grade: >98%. Molecular formula: C100H168N32O19S. Mole weight: 2154.69. | |
| Ziprasidone | Ziprasidone (CP-88059), an orally active antipsychotic agent, is a combined 5-HT and dopamine receptor antagonist [1]. Ziprasidone mesylate trihydrate has affinities for Rat D 2 ( K i =4.8 nM), 5-HT 2A ( K i =0.42 nM) and 5-HT 1A ( K i =3.4 nM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-88059. CAS No. 146939-27-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14542. | |
| Ziprasidone | Ziprasidone. Group: Biochemicals. Grades: Highly Purified. CAS No. 146939-27-7. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C21H21ClN4OS. US Biological Life Sciences. | Worldwide |
| Ziprasidone Amino Acid Sodium Salt (Ziprasidone Impurity C) | Ziprasidone impurity C. Group: Biochemicals. Alternative Names: [2-Amino-5-[2-[4-(1,2-benzisothiazol-3-yl)piperazin-1-yl]ethyl]-4-chlorophenyl]acetic Acid Sodium Salt; 2-Amino-5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-4-chlorobenzeneacetic Acid; Ziprasidone Impurity C. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ziprasidone-[d8] | A labelled form of Ziprasidone which is an antagonist of both 5-HT and dopamine receptor and it has been studied to show effective antipsychotic activity. Uses: A labelled form of ziprasidone which is an antagonist of both 5-ht and dopamine receptor and has been studied to show effective antipsychotic activity. Synonyms: Ziprasidone-d8; 5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl-d8]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one; 5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl-d8]ethyl]-6-chloro-2-indolinone; 5-[2-[4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one-d8; Geodon-d8; Zeldox-d8. Grade: 97% by CP; 97% atom D. CAS No. 1126745-58-1. Molecular formula: C21H13D8ClN4OS. Mole weight: 452.92. | |
| Ziprasidone-D8 | Ziprasidone-D8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1126745-58-1. Molecular formula: C21H13D8ClN4OS. Mole weight: 420.99. Catalog: APB1126745581. |  |
| Ziprasidone-d8 (5-[2-[4-(1,2-Benzisothiazol-3yl)-1-piperazinyl-d8]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one) | Labelled Ziprasidone, which is used as an antipsychotic. Group: Biochemicals. Alternative Names: 5-[2-[4-(1,2-Benzisothiazol-3yl)-1-piperazinyl-d8]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one. Grades: Highly Purified. CAS No. 146939-27-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ziprasidone EP Impurity A | An impurity of Ziprasidone, a combined serotonin (5HT2) and dopamine (D2) receptor antagonist. Synonyms: 3-(1-Piperazinyl)-1,2-benzisothiazole; 3-(piperazin-1-yl)benzo[d]isothiazole; 3-Piperazin-1-yl-benzo[d]isothiazole; Ziprasidone Related Compound A. Grade: 98.0%. CAS No. 87691-87-0. Molecular formula: C11H13N3S. Mole weight: 219.31. | |
| Ziprasidone HCL | The hydrochloride monohydrate salt form of Ziprasidone, a benzothiazol derivative, has been found to be a 5HT2A and D2 receptor antagonist that could be used against schizophrenia and other sorts of psychotic. pKi: 9.38 and 8.32 for 5-HT2A and D2 receptor. Alternative Names: Ziprasidone hydrochloride monohydrate. Geodon. Ziprasidone HCl hydrate. 5-(2-(4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one hydrochloride hydrate. CAS No. 138982-67-9. Product ID: API138982679. Molecular formula: C21H24Cl2N4O2S. Mole weight: 467.4. EINECS: 638-781-0. SMILES: C1CN(CCN1CCC2=C(C=C3C(=C2)CC(=O)N3)Cl)C4=NSC5=CC=CC=C54.O.Cl. Appearance: Pale Tan Powder. Category: Antipsychotic APIs. |  |
| Ziprasidone hydrochloride | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Ziprasidone hydrochloride | Ziprasidone hydrochloride. Group: Biochemicals. Alternative Names: 5-[2-[4-(1,2-Benzisothiazol-3yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one. Grades: Highly Purified. CAS No. 122883-93-6. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C21H21ClN4OS·HCl. US Biological Life Sciences. | Worldwide |
| Ziprasidone hydrochloride monohydrate | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopyapi standardseuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: Ziprasidone Hydrochloride Monohydrate. | |
| Ziprasidone hydrochloride monohydrate | Ziprasidone (CP-88059) hydrochloride monohydrate is an orally active combined 5-HT and dopamine receptor antagonist [1]. Ziprasidone hydrochloride monohydrate has affinities for Rat D 2 ( K i =4.8 nM), 5-HT 2A ( K i =0.42 nM) and 5-HT 1A ( K i =3.4 nM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP 88059 hydrochloride monohydrate. CAS No. 138982-67-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-17407. | |
| Ziprasidone hydrochloride monohydrate | Ziprasidone hydrochloride monohydrate. Group: Biochemicals. Alternative Names: 5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one hydrochloride monohydrate, CP-88059-1; Geodon hydrochloride hydrate. Grades: Highly Purified. CAS No. 138982-67-9. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C21H24Cl2N4O2S. US Biological Life Sciences. | Worldwide |
| Ziprasidone, Hydrochloride Monohydrate (5-[2-[4-(1,2-Benzisothiazol-3yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one, Hydrochloride Monohydrate, CP-88059-1) | Used as an antipsychotic. Group: Biochemicals. Alternative Names: 5-[2-[4-(1,2-Benzisothiazol-3yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one, Hydrochloride Monohydrate, CP-88059-1. Grades: Highly Purified. CAS No. 138982-67-9. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| Ziprasidone Related Compound B | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Ziprasidone Related Compound C | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Ziprasidone Related Compound D | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Ziprasidone Sulfone Hydrochloride | A metabolite of Ziprasidone. Group: Biochemicals. Alternative Names: 6-Chloro-5-[2-[4-(1,1-dioxido-1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-1,3-dihydro-. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Ziprasidone Sulfoxide | A metabolite of Ziprasidone. Group: Biochemicals. Alternative Names: 6-Chloro-1,3-dihydro-5-[2-[4-(1-oxido-1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-. Grades: Highly Purified. CAS No. 188797-80-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| ZIP (Scrambled) | ZIP (Scrambled). Group: Biochemicals. Grades: Purified. CAS No. 908012-18-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| ZIP (Scrambled) | ZIP (Scrambled) is a scrambled control peptide for ZIP. Synonyms: z-Pseudosubstrate inhibitory peptide (scrambled); myristoyl-Arg-Leu-Tyr-Arg-Lys-Arg-Ile-Trp-Arg-Ser-Ala-Gly-Arg-OH; N-myristoyl-L-arginyl-L-leucyl-L-tyrosyl-L-arginyl-L-lysyl-L-arginyl-L-isoleucyl-L-tryptophyl-L-arginyl-L-seryl-L-alanyl-glycyl-L-arginine. Grade: >98%. CAS No. 908012-18-0. Molecular formula: C90H154N30O17. Mole weight: 1928.38. | |
| ZIP (Scrambled) acetate | ZIP (Scrambled) TFA, a scrambled peptide, can be used as a negative control for zeta inhibitory peptide (ZIP). Synonyms: myristoyl-Arg-Leu-Tyr-Arg-Lys-Arg-Ile-Trp-Arg-Ser-Ala-Gly-Arg-OH.CH3CO2H; N-myristoyl-L-arginyl-L-leucyl-L-tyrosyl-L-arginyl-L-lysyl-L-arginyl-L-isoleucyl-L-tryptophyl-L-arginyl-L-seryl-L-alanyl-glycyl-L-arginine acetic acid. Grade: ≥95%. CAS No. 2763584-14-9. Molecular formula: C92H158N30O19. Mole weight: 1988.43. | |
| 3-(1-Piperazinyl)-1,2-benzisothiazole Hydrochloride (1:1). (Ziprasidone Related Compound A) | 3-(1-Piperazinyl)-1,2-benzisothiazole Hydrochloride (1:1)(Ziprasidone Related Compound A). Group: Biochemicals. Alternative Names: 3-(1-Piperazinyl)-1,2-benzisothiazole Monohydrochloride; 3-Piperazin-1-yl-benzo[d]isothiazole Hydrochloride; 3-Piperazinyl-1,2-benzisothiazole Hydrochloride; 4-(1,2-Benzisothiazol-3-yl)piperazine Hydrochloride; (3-(Piperazin-1-yl)benzo[d]isothiazole Monohydrochloride. Grades: Highly Purified. CAS No. 87691-88-1. Pack Sizes: 2.5mg. Molecular Formula: C11H14ClN3S, Molecular Weight: 255.77. US Biological Life Sciences. | Worldwide |
| Anti-Zip Kinase antibody produced in rabbit | affinity isolated antibody, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Hydroxy Ziprasidone | An impurity of Ziprasidone, a combined serotonin (5HT2) and dopamine (D2) receptor antagonist. Synonyms: 5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]-1-hydroxyethyl]-6-chloro-1,3-dihydro-2H-indol-2-one. CAS No. 884305-08-2. Molecular formula: C21H21ClN4O2S. Mole weight: 428.94. | |
| 10074-G5 | 10074-G5, similarly to 10058-F4, is an inhibitor of c-Myc-Maxdimerization (IC50 = 146 μM) that suppresses its transcriptional activity. 10074-G5 binds to and distorts the bHLH-ZIP domain of c-Myc (Kd = 2.8 μM), thus preventing C-Myc specific DNA binding and target genes regulation. Synonyms: 10074 G5; Biphenyl-2-yl-(7-nitrobenzo[1,2,5]oxadiazol-4-yl)amine; 10074G5. CAS No. 413611-93-5. Molecular formula: C18H12N4O3. Mole weight: 332.31. | |
| 1- (1-Oxidobenzo [d]isothiazol-3-yl) piperazine 1-Oxide Hydrochloride | 1- (1-Oxidobenzo [d]isothiazol-3-yl) piperazine 1-Oxide Hydrochloride is an intermediate in the synthesis of Ziprasidone related compounds. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 50mg. Molecular Formula: C11H14ClN3O2S. US Biological Life Sciences. | Worldwide |
| 2-[5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-4-chloro-2-nitrophenyl]-propanedioic Acid 1,3-Dimethyl Ester | Intermediate in the synthesis of the antipsychotic agent Ziprasidone. Group: Biochemicals. Alternative Names: [5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-4-chloro-2-nitrophenyl]-propanedioic Acid Dimethyl Ester. Grades: Highly Purified. CAS No. 160384-39-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 2-Amino-4-chlorobenzeneacetic acid | An impurity of Ziprasidone, a combined serotonin (5HT2) and dopamine (D2) receptor antagonist. Synonyms: Ziprasidone Impurity 18; (2-Amino-4-chlorophenyl)acetic acid. Grade: ≥95%. CAS No. 177985-31-8. Molecular formula: C8H8ClNO2. Mole weight: 185.61. | |
| 3-(1-Piperazinyl)-1,2-benzisothiazole | A reagent used to synthesize Ziprasidione. Group: Biochemicals. Alternative Names: 3-(Piperazin-1-yl)benzoisothiazole; N- (3-Benzisothiazolyl) piperazine; 1-(1,2-Benzisothiazol-3-yl)piperazine. Grades: Highly Purified. CAS No. 87691-87-0. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| 3-(1-Piperazinyl)-1,2-benzisothiazole 1-Oxide | 3-(1-Piperazinyl)-1,2-benzisothiazole 1-Oxide is an intermediate in synthesizing Ziprasidone Sulfoxide (), a metabolite of Ziprasidone (Z485000). Group: Biochemicals. Grades: Highly Purified. CAS No. 128396-56-5. Pack Sizes: 25mg, 50mg. Molecular Formula: C11H13N3OS. US Biological Life Sciences. | Worldwide |
| 3-(1-Piperazinyl-d8)-1,2-benzisothiazole | 3-(1-Piperazinyl-d8)-1,2-benzisothiazole is the labeled analogue of 3-(1-Piperazinyl)-1,2-benzisothiazole (P480600), a reagent used to synthesize Ziprasidone(Z485000), a combined serotonin (5HT2) and dopamine (D2) receptor antagonist. Used as an antipsychotic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C11H5D8N3S, Molecular Weight: 227.36. US Biological Life Sciences. | Worldwide |
| 3-[4-[2-(2,5-Dichloro-4-nitrophenyl)ethenyl]-1-piperazinyl]-1,2-benzisothiazole | Intermediate in the synthesis of the antipsychotic agent Ziprasidone. Group: Biochemicals. Grades: Highly Purified. CAS No. 160384-37-2. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 3-[4-[2-(2,5-Dichloro-4-nitrophenyl)ethyl]-1-piperazinyl]-1,2-benzisothiazole | Intermediate in the synthesis of the antipsychotic agent Ziprasidone. Group: Biochemicals. Grades: Highly Purified. CAS No. 160384-38-3. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| (3-(Benzo[d]isothiazol-3-yl)-5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one). . | (3-(Benzo[d]isothiazol-3-yl)-5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one). Group: Biochemicals. Alternative Names: Ziprasidone Related Compound D. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C28H24ClN5OS2, Molecular Weight: 546.11. US Biological Life Sciences. | Worldwide |
| 3MB-PP1 | 3MB-PP1, a bulky purine analog, is a Polo-like kinase 1 (Plk1) inhibitor. 3MB-PP1 blocks mitotic progression and cell division arise through target Plk1 in in cells expressing analog-sensitive Plk1 alleles. 3MB-PP1 specifically inhibits the activity of analog-sensitive Ssn3 (Cdk8). 3MB-PP1 inhibits Leu93 Mutant Zipper-interacting protein kinase (Leu93-ZIPK; IC50=2 ?M). 3MB-PP1 can be used for the research of hypha formation of Candida albicans and cell division[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 956025-83-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102069. | |
| 5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-4-chloro-2-nitro-benzeneacetic Acid | Ziprasidone derivative. Group: Biochemicals. Alternative Names: [2-Nitro-5-[2-[4-(1,2-benzisothiazol-3-yl)piperazin-1-yl]ethyl]-4-chlorophenyl]acetic Acid. Grades: Highly Purified. CAS No. 160384-40-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl-4-chloro-2-nitrophenol | Impurity in the synthesis of the antipsychotic agent Ziprasidone. Group: Biochemicals. Alternative Names: 3-[4-[2-(2-Chloro-5-hydroxy-4-nitrophenyl)ethyl]-1-piperazinyl]-1,2-Benzisothiazole. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| (5-(2-(4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindoline-2,3-dione). | (5-(2-(4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindoline-2,3-dione). Group: Biochemicals. Alternative Names: Ziprasidone Related Compound B. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C21H19ClN4O2S, Molecular Weight: 426.92. US Biological Life Sciences. | Worldwide |
| (5,5-Bis(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6,6-dichloro-3-hydroxy-3,3-biindoline-2,2-dione). | (5,5-Bis(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6,6-dichloro-3-hydroxy-3,3-biindoline-2,2-dione). Group: Biochemicals. Alternative Names: Ziprasidone Related Compound C. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C42H40Cl2N8O3S2, Molecular Weight: 839.85. US Biological Life Sciences. | Worldwide |
| 6-Chloro-2-oxindole | An impurity of Ziprasidone, a combined serotonin (5HT2) and dopamine (D2) receptor antagonist. Synonyms: Chloroindolinone; 6-Chlorooxindole; 6-chloroindolin-2-one; 6-Chloro-1,3-dihydro-2H-indol-2-one. CAS No. 56341-37-8. Molecular formula: C8H6ClNO. Mole weight: 167.59. | |
| 6-Chloro-5-(2-chloroethyl)oxindole | An impurity of Ziprasidone, a combined serotonin (5HT2) and dopamine (D2) receptor antagonist. Synonyms: 5-(2-Chloroethyl)-6-chlorooxindole. CAS No. 118289-55-7. Molecular formula: C10H9Cl2NO. Mole weight: 230.09. | |
| CEP-1347 | CEP-1347 is an inhibitor of the JNK/SAPK pathway with neuroprotective effects. CEP-1347 blocks JNK1 activation induced by members of the mixed lineage kinase (MLK) family (MLK3, MLK2, MLK1, dual leucine zipper kinase, and leucine zipper kinase). As an inhibitor of MDM4 , CEP-1347 can more effectively inhibit the growth of glioma cells expressing wild-type p53 [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KT7515. CAS No. 156177-65-0. Pack Sizes: 1 mg. Product ID: HY-10412. | |
| Diclofenac potassium | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardsapi standardseuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: K-Fenak, CGP 45840B, K-fenak, Acetic acid, [o-(2,6-dichloroanilino)phenyl]-, monopotassium salt (8CI),Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, potassium salt (1:1), Diclofenac potassium, ProSorb, Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, monopotassium salt (9CI), Caflam, Cambia, Cataflam, Potassium diclofenac, Zipsor. | |
| Diclofenac Potassium | For rheumatoid arthritis, dysmenorrhea, femoral arthritis, spondylitis. Alternative Names: Cataflam. Cambia. Zipsor. CAS No. 15307-81-0. Product ID: API15307810. Molecular formula: C14H10Cl2KNO2. Mole weight: 334.2. EINECS: 630-422-6. SMILES: C1=CC=C(C(=C1)CC(=O)[O-])NC2=C(C=CC=C2Cl)Cl.[K+]. Appearance: White to Off-white Solid. Category: Anti-Gout APIs. | |
| DLK-IN-1 | DLK-IN-1 is a selective oral active inhibitor of bisleucine zipper kinase (DLK, MAP3K12) with Ki of 3 nM. Synonyms: DLK-IN-1; 1620574-24-4; CHEMBL3719135; 5-[5-[(1R,5S)-3-(oxetan-3-yl)-3-azabicyclo[3.1.0]hexan-6-yl]-1-propan-2-ylpyrazol-3-yl]-3-(trifluoromethoxy)pyridin-2-amine; SCHEMBL15890128; SCHEMBL17387965; SCHEMBL19921639; UHEFRVBGJORHNV-UOIKSKOESA-N; UHEFRVBGJORHNV-UUVAVEHKSA-N; BDBM50271207; AKOS040732992; MS-27433; HY-114331; CS-0083054. Grade: 99%. CAS No. 1620574-24-4. Molecular formula: C20H24F3N5O2. Mole weight: 423.43. | |
| GNE-3511 | GNE-3511 is an orally active bioavailable and brain-penetrant dual leucine zipper kinase (DLK) inhibitor with a Ki of 0.5 nM. GNE-3511 can cross the blood-brain-barrier and can be used for the research of neurodegenerative diseases[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1496581-76-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12947. | |
| GNE-8505 | GNE-8505 is an orally available dual leucine zipper kinase (DLK) inhibitor. Synonyms: example 152 [WO2014111496]. CAS No. 1620573-48-9. Molecular formula: C21H24F3N5O. Mole weight: 419.44. | |
| GNE-8505 | GNE-8505 is an orally available inhibitor of Dual leucine zipper kinase (DLK)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1620573-48-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-114332. | |
| HPPE | HPPE (compound 236) is an orally active, potential Bach1 inhibitor. Bach1 is a transcription factor of the cap'n'collar type alkaline region leucine zipper factor family (CNC-bZip) that regulates mitochondrial metabolism and reduces glucose utilization. HPPE can be used for research in psoriasis, multiple sclerosis, and COPD [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bach1-IN-1. CAS No. 1325721-55-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-153040. | |
| HS 38 | HS 38 is an ATP-competitive inhibitor of DAPK (IC50 = 200 nM) and ZIPK (Kd = 280 nM). It also inhibits PIM3 kinase (IC50 = 200 nM) with no significant effect on Src or Abl kinases. HS 38 regulates programmed cell death and phosphorylation of non-muscle and smooth muscle myosin. Synonyms: HS 38; HS38; HS-38; 2-[[1-(3-Chlorophenyl)-4,5-dihydro-4-oxo-1H-pyrazolo[3,4-d]pyrimidin-6-yl]thio]propanamide. Grade: ≥98% by HPLC. CAS No. 1030203-81-6. Molecular formula: C14H12CIN5O2S. Mole weight: 349.8. | |
| Zolmitriptan | Zolmitriptan is a selective serotonin receptor agonist used to treat migraine. Uses: Serotonin 5-ht1 receptor agonists. Synonyms: (4S)-4-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl-2-oxazolidinone; BW-311C90; Zomig; 2-Oxazolidinone, 4-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-, (4S)-; 2-Oxazolidinone, 4-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-, (S)-; (4S)-4-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]oxazolidin-2-one; (S)-4-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]-2-oxazolidinone; 311C90; Amigrawest; Asco Top; BW 311C90; No-migraine Z; Xolnox; Zipton; Zominat. Grade: >98%. CAS No. 139264-17-8. Molecular formula: C16H21N3O2. Mole weight: 287.36. | |
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