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| Product | Description | |
|---|---|---|
| a-Methyl-2-piperidinemethanol | a-Methyl-2-piperidinemethanol. Group: Biochemicals. Alternative Names: 1-(2-Piperidyl)ethanol; 2- (1'-Hydroxyethyl) piperidine; Methyl(2-piperidyl)carbinol. Grades: Highly Purified. CAS No. 54160-32-6. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C7H15NO. US Biological Life Sciences. |  Worldwide |
| a-Methyl-(3-benzyloxy)benzyl alcohol ≥97% (GC) | a-Methyl-(3-benzyloxy)benzyl alcohol ≥97% (GC). Group: Biochemicals. Grades: GC. Pack Sizes: 250mg, 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| a-Methyl-5-(2-thienylmethoxy)-1H-indole-3-ethanamine monohydrochloride | a-Methyl-5-(2-thienylmethoxy)-1H-indole-3-ethanamine monohydrochloride. Group: Biochemicals. Alternative Names: BW 723C86. Grades: Highly Purified. CAS No. 160521-72-2. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C16H19ClN2OS. US Biological Life Sciences. | Worldwide |
| a-Methyl-5H-[1]benzopyrano[2,3-b]pyridine-7-acetic acid | a-Methyl-5H-[1]benzopyrano[2,3-b]pyridine-7-acetic acid. Group: Biochemicals. Alternative Names: Pranoprofen ; (+/-)-Pranoprofen; 2-(5H-[1]-Benzopyrano[2,3-b]pyridin-7-yl)propionic acid. Grades: Highly Purified. CAS No. 52549-17-4. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C15H13NO3. US Biological Life Sciences. | Worldwide |
| a-Methyl-5-hydroxytryptaminemaleate | a-Methyl-5-hydroxytryptaminemaleate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 304-52-9. Molecular Formula: C11H14N2O. Mole Weight: 190.25. Catalog: APB304529. |  |
| a-Methyl-5-pyrimidinemethanol | a-Methyl-5-pyrimidinemethanol. Group: Biochemicals. Alternative Names: 1-(Pyrimidin-5-yl)ethan-1-ol. Grades: Highly Purified. CAS No. 79691-74-0. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C6H8N2O. US Biological Life Sciences. | Worldwide |
| A-METHYLBENZYLZINC BROMIDE | A-METHYLBENZYLZINC BROMIDE. Group: Salt. Alternative Names: 85459-20-7, 498777_ALDRICH, |A-Methylbenzylzinc bromide solution, AKOS016018002, alpha-Methylbenzylzinc bromide solution, a-Methylbenzylzinc bromide 0.5 M in Tetrahydrofuran. CAS No. 85459-20-7. Product ID: bromozinc(1+); ethylbenzene. Molecular formula: 250.45. Mole weight: C8H9BrZn. C[CH-]C1=CC=CC=C1.[Zn+]Br. LCPVHNNFHPWFCI-UHFFFAOYSA-M. 96%. |  |
| a-Methyl cinnamic acid | a-Methyl cinnamic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 1199-77-5. Pack Sizes: 50g, 100g. Molecular Formula: C10H10O2. US Biological Life Sciences. | Worldwide |
| a-Methyl-D-4-Fluorophenylalanine 98+% (HPLC) | a-Methyl-D-4-Fluorophenylalanine 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 2.5g. US Biological Life Sciences. | Worldwide |
| a-Methyl-DL-phenylalanine 98+% (HPLC) | a-Methyl-DL-phenylalanine 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| a-Methyl-DL-phenylalanine methyl ester hydrochloride | a-Methyl-DL-phenylalanine methyl ester hydrochloride. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| a-Methyl-D,L-serine (D, L-a- (Hydroxymethyl) alanine) | A serine derivative. Used in the synthesis of constrained amino acid buildings blocks and their incorporation into biologically active peptidomimetics. Group: Biochemicals. Alternative Names: D, L-a- (Hydroxymethyl) alanine. Grades: Highly Purified. CAS No. 5424-29-3. Pack Sizes: 1g, 5g, 10g. US Biological Life Sciences. | Worldwide |
| a-Methyl-D,L-tryptophan, Methyl Ester | a-Methyl-D,L-tryptophan, Methyl Ester. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| a-Methyl-D,L-tyrosine | A tyrosine hydroxylase inhibitor. An antihypertensive in pheochromocytoma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
| a-Methyl-DL-valine 99+% | a-Methyl-DL-valine 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences. | Worldwide |
| a-Methyl-D-phenylalanine | a-Methyl-D-phenylalanine. Group: Biochemicals. Alternative Names: a-Me-D-Phe-OH; (R)-2-Amino-2-methyl-3-phenylpropanoic acid. Grades: Highly Purified. CAS No. 17350-84-4. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences. | Worldwide |
| a-Methyl-D-phenylalanine 99+% (Chiral HPLC) | a-Methyl-D-phenylalanine 99+% (Chiral HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences. | Worldwide |
| a-Methyl-D-serine ((-)-2-Methyl-D-serine, (R)-(-)-2-Amino-3-hydroxy-2-methylpropionic Acid) | Melting Point: >260°C (dec). Group: Biochemicals. Alternative Names: (-)-2-Methyl-D-serine; (R)-(-)-2-Amino-3-hydroxy-2-methylpropionic Acid. Grades: Highly Purified. CAS No. 81132-44-7. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| a-Methyl-D-valine 98+% (NMR) | a-Methyl-D-valine 98+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences. | Worldwide |
| a-Methylene-gamma-butyrolactone | a-Methylene-gamma-butyrolactone. Group: Biochemicals. Alternative Names: 3-Methylenedihydro-2(3H)-furanone; Tulipane. Grades: Highly Purified. CAS No. 547-65-9. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C5H6O2. US Biological Life Sciences. | Worldwide |
| a-Methyl-L-4-Fluorophenylalanine 98+% (HPLC) | a-Methyl-L-4-Fluorophenylalanine 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 2.5g. US Biological Life Sciences. | Worldwide |
| a-Methyl-L-phenylalanine 99+% | a-Methyl-L-phenylalanine 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences. | Worldwide |
| a-Methyl-L-phenylalanine methyl ester hydrochloride ≥97% (HPLC) | a-Methyl-L-phenylalanine methyl ester hydrochloride ≥97% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences. | Worldwide |
| a-Methyl-L-p-tyrosine (AMPT, Metyrosine,) | A tyrosine hydroxylase inhibitor. An antihypertensive in pheochromocytoma. Group: Biochemicals. Alternative Names: AMPT, Metyrosine. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| a-Methyl-L-tryptophan | Atmosphere: Group: Biochemicals. Alternative Names: (-)-a--Methyltryptophan; a-Methyl-(S)-tryptophan; L-a-Methyltryptophan. Grades: Highly Purified. CAS No. 16709-25-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| a-Methyl-L-valine | a-Methyl-L-valine. Group: Biochemicals. Alternative Names: a-Me-L-Val-OH. Grades: Highly Purified. CAS No. 53940-83-3. Pack Sizes: 500mg, 1g, 2g, 5g. US Biological Life Sciences. | Worldwide |
| a-Methyl-L-valine 99+% (TLC) | a-Methyl-L-valine 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences. | Worldwide |
| a-Methyl-phenothiazine-10-ethanal | a-Methyl-phenothiazine-10-ethanal. Group: Biochemicals. Alternative Names: 1-(10H-Phenothiazin-10-yl)-2-propanone; Phenothiazin-10-yl-2-propanone. Grades: Highly Purified. CAS No. 15375-56-1. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C15H13NOS. US Biological Life Sciences. | Worldwide |
| a-Methyl-phenothiazine-10-ethanol | a-Methyl-phenothiazine-10-ethanol. Group: Biochemicals. Alternative Names: a-Methyl-10H-phenothiazine-10-ethanol; 10- (b-Hydroxypropyl) phenothiazine. Grades: Highly Purified. CAS No. 32209-47-5. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C15H15NOS. US Biological Life Sciences. | Worldwide |
| Amethyst violet | Amethyst violet. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AMETHYST VIOLET;CI 50225. Product Category: Heterocyclic Organic Compound. CAS No. 3562-38-7. Molecular formula: C26H31ClN4. Mole weight: 435. Purity: biological stain. Product ID: ACM3562387. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Ametoctradin | Ametoctradin ist eine chemische Verbindung aus der Gruppe der Triazol-Pyrimidylamine. Synonyms: 5-Ethyl-6-octyl[1,2,4]?triazolo[1,5-a]pyrimidin-7-amin. Grades: > 95%. CAS No. 865318-97-4. Molecular formula: C15H25N5. Mole weight: 275.4. |  |
| Ametoctradin | Ametoctradin acts as a pesticide, and is used in fomulations of insecticides and fungicides. Group: Biochemicals. Grades: Highly Purified. CAS No. 865318-97-4. Pack Sizes: 25mg, 50mg. Molecular Formula: C15H25N5, Molecular Weight: 275.39. US Biological Life Sciences. | Worldwide |
| Ametryn | Ametryn. Group: Biochemicals. Alternative Names: Ametryne; Cemerin; Doruplant; Evik; G 34162; Gesapax; N-Ethyl-N'-(1-methylethyl)-6-(methylthio)-1,3,5-triazine-2,4-diamine; NSC 163044; Primatol Z 80; 2-Ethylamino-4-isopropylamino-6-methylmercapto-s-triazine; 2-Ethylamino-4-isopropylamino-6-methylthio-1,3,5-triazine; 2-Ethylamino-4-isopropylamino-6-methylthio-s-triazine; 2-Ethylamino-4-methylthio-6-isopropylamino-1,3,5-triazine; 2-Methylmercapto-4-ethylamino-6-isopropylamino-s-triazine; 2-Methylthio-4-ethylamino-6-isopropylamino-s-triazine; 2-Methylthio-4-ethylamino-6-isopropylamino-sym-triazine; A 1093; Amephyt; Ametrex; 2-(Ethylamino)-4-(isopropylamino)-6-(methylthio)-s-triazine; N-Ethyl-N'-(1-methylethyl)-6-(methylthio)-1,3,5-triazine-2,4-diamine; N2-Ethyl-N4-(1-methylethyl)-6-(methylthio)-1,3,5-triazine-2,4-diamine. Grades: Highly Purified. CAS No. 834-12-8. Pack Sizes: 1g. Molecular Formula: C9H17N5S, Molecular Weight: 227.33. US Biological Life Sciences. | Worldwide |
| Ametryn | Ametryn, a member of the Triazine chemical family, is a herbicide which inhibits photosynthesis and other enzymatic processes. Ametryn is effective against annual broadleaf weeds and grasses [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 834-12-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-B0866. |  |
| Amezinium methylsulfate | Amezinium methylsulfate, a sympathomimetic drug used for the treatment of low blood pressure, increases the arterial blood pressure and heart rate of anaesthetized animals and of pithed rats by stimulating vascular alpha- and cardiac beta 1-adrenoceptors. Synonyms: Amezinium Metilsulfate; LU-1631; LU 1631; LU1631; Regulton; Risumic. 6-methoxy-1-phenylpyridazin-1-ium-4-amine methylsulfate;AMEZINIUM METHYL SULFATE;SUPRATONIN (GRUNENTHAL);RISUMIC (DAINIPPON);REGULTON (KNOLL);4-amino-6-methoxy-1-phenyl-pyridaziniumethylsulfate;4-amino-6-methoxy-1-phenylpyridazinium-methylsulfat;4-amino-. CAS No. 30578-37-1. Molecular formula: C11H12N3O.CH3O4S. Mole weight: 313.33. | |
| Amezinium methylsulfate | Amezinium metilsulfate has multiple mechanisms, including stimulation of alpha and beta-1 receptors and inhibition ofnoradrenaline and tyramine uptake. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Amezinium metilsulfate; Lu-1631. CAS No. 30578-37-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-A0275. | |
| Amezinium Methyl Sulfate | Amezinium Methyl Sulfate. Group: Biochemicals. Grades: Highly Purified. CAS No. 30578-37-1. Pack Sizes: 250mg, 5mg, 10g, 25g, 50g. Molecular Formula: C12H15N3O5S. US Biological Life Sciences. | Worldwide |
| AMF | AMF. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4'-(Aminomethyl)fluorescein. Product Category: Fluorescein Fluorophores. CAS No. 91539-64-9. Molecular formula: C21H16ClNO5. Mole weight: 397.81. Purity: 95%+. IUPACName: 7-(aminomethyl)-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one;hydrochloride. Product ID: ACM91539649-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| Amfefenac impurity 1 | Amfefenac impurity 1. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C21H21NO9. Mole Weight: 431.4. Catalog: APB11482. | |
| Amfenac | Amfenac (2-Amino-3-benzoylbenzeneacetic acid) is a non-steroidal anti-inflammatory drug with acetic acid moiety. Synonyms: 2-Amino-3-benzoylphenylacetic acid; 2-Amino-3-benzoylbenzeneacetic acid; 2-(2-amino-3-benzoyl-phenyl)acetic acid. Grades: > 95%. CAS No. 51579-82-9. Molecular formula: C15H13NO3. Mole weight: 255.28. | |
| Amfenac Ethyl Ester | Amfenac Ethyl Ester. Uses: For analytical and research use. Group: Impurity standards. CAS No. 61941-57-9. IUPAC Name: ethyl 2-(2-amino-3-benzoylphenyl)acetate. Molecular Formula: C17H17NO3. Mole Weight: 283.32. Catalog: APS61941579. SMILES: CCOC(=O)Cc1cccc(C(=O)c2ccccc2)c1N. Format: Neat. Shipping: Room Temperature. | |
| Amfenac Lactam | A metabolite of Amfenac. Synonyms: 7-Benzoyl-1,3-dihydro-2H-indol-2-one; 7-Benzoyl-2-indolinone. Grades: > 95%. CAS No. 51135-38-7. Molecular formula: C15H11NO2. Mole weight: 237.26. | |
| Amfenac Sodium | 2-Amino-3-benzoylbenzeneacetic acid, monosodium salt, monohydrate. Grades: CAS No. 61618-27-7. Product ID: 8-04532. Molecular formula: C15H14NO4Na. Mole weight: 295.27. |  |
| Amfenac Sodium Hydrate | Amfenac is an antibacterial agent. Group: Biochemicals. Alternative Names: 2-Amino-3-benzoylbenzeneacetic Acid Sodium Salt Hydrate; (2-Amino-3-benzoylphenyl)acetic Acid; NSC 309467. Grades: Highly Purified. CAS No. 61618-27-7. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Amfenac Sodium Hydrate | Amfenac Sodium Hydrate is a COX-2 inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 61618-27-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-17479A. | |
| Amfenac sodium salt hydrate | Amfenac sodium salt hydrate. Group: Biochemicals. Alternative Names: 2-Amino-3-benzoylbenzeneacetic acid sodium salt hydrate; (2-Amino-3-benzoylphenyl)acetic acid; NSC 309467. Grades: Highly Purified. CAS No. 61618-27-7. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C15H14NNaO4. US Biological Life Sciences. | Worldwide |
| Amflutizole | Amflutizole is a xanthine oxidase inhibitor. It inhibits free radical generation in the ischemic/reperfused rat cerebral cortex. Synonyms: 4-Amino-3-(3-(trifluoromethyl)phenyl)isothiazole-5-carboxylic acid. CAS No. 82114-19-0. Molecular formula: C11H7F3N2O2S. Mole weight: 288.25. | |
| Amfonelic acid | Amfonelic acid (AFA; WIN 25,978) is a research chemical and dopaminergic stimulant with antibiotic properties. Synonyms: AMFONELIC ACID; AMFONELIC ACID INCREASES DOPAMINE RE; amfonelic acid (7-benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid); Amfonelic; 7-Benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid; NCA. Grades: 95%. CAS No. 15180-02-6. Molecular formula: C18H16N2O3. Mole weight: 308.33. | |
| AMG-009 | AMG-009 is an orally active, small molecule dual D prostanoid(DP) receptor and chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) antagonist. It was in preclinical development for the treatment of asthma and allergic rhinitis. It was developed by Amgen Inc. Uses: Amg-009 was in preclinical development for the treatment of asthma and allergic rhinitis. Synonyms: AMG-009; AMG 009; AMG009; 2-[4-[4- (Butylcarbamoyl) -2-[ (2, 4-dichlorophenyl) sulfonylamino]phenoxy]-3-methoxyphenyl]acetic acid;AMG009;Benzeneacetic acid, 4- (4- ( (butylamino) carbonyl) -2- ( ( (2, 4-dichlorophenyl) sulfonyl) amino) phenoxy) -3-methoxy-. Grades: >98 %. CAS No. 1027847-67-1. Molecular formula: C26H26Cl2N2O7S. Mole weight: 581.46. | |
| AMG-126737 | AMG-126737 is a potent inhibitor of human lung mast cell tryptase (Ki = 90 nM), with greater than 10- to 200-fold selectivity versus other serine proteases. Synonyms: 3- [ [4- [5- [4- [ [ (3-carbamimidoylphenyl) sulfonylamino] methyl] phenoxy] pentoxy] phenyl] methylsulfamoyl] benzenecarboximidamide; 1,5-bis-(4-((3-carbamimidoyl-benzenesulfonylamino)-methyl)-phenoxy)-pentane; AMG-126737; AMG 126737; AMG126737. Grades: >98%. CAS No. 224054-76-6. Molecular formula: C33H38N6O6S2. Mole weight: 678.82. | |
| AMG176 | AMG176. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1883727-34-1. Molecular Formula: C33H41ClN2O5S. Mole Weight: 613.21. Catalog: APB1883727341. | |
| AMG 18 hydrochloride | AMG-18 hydrochloride is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM. AMG-18 is a potent and selective IRE1α inhibitor with IC50 of 13 nM for recombinant and IC50 of 99 nM for cellular IRE1&alpha. Synonyms: 2-Chloro-N-[6-methyl-5-[[3-[2-[(3S)-3-piperidinylamino]-4-pyrimidinyl]-2-pyridinyl]oxy]-1-naphthalenyl]benzenesulfonamide hydrochloride; Kira8 hydrochloride. Grades: ≥98% by HPLC. Molecular formula: C31H29ClN6O3S·HCl. Mole weight: 637.58. | |
| AMG-193 | AMG 193 is an orally active MTA-cooperative PRMT5 inhibitor with antitumor activity. AMG 193, when complexed with MTA, preferentially inhibits the growth of MTAP-deficient tumor cells by inhibiting PRMT5 ( IC 50 =0.107 μM), thereby protecting normal cells with wild-type MTAP [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2790567-82-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153390. | |
| AMG208 | AMG 208 is a selective small-molecule inhibitor of the proto-oncogene c-Met with potential antineoplastic activity. C-Met encodes the hepatocyte growth factor receptor tyrosine kinase, plays an important role in epithelial cell proliferation and has been shown to be overexpressed in a variety of cancers. Synonyms: AMG-208; AMG208; AMG 208. Grades: 0.98. CAS No. 1002304-34-8. Molecular formula: C22H17N5O2. Mole weight: 383.411. | |
| AMG 21629 | AMG 21629 has been found to be an effective and selective TRPV1 antagonist, which could probably be useful in the treatment of pains associated with cancer and inflammatory diseases. Synonyms: AMG21629; AMG-21629; AMG 21629; 3-Amino-5-[[2-[(2-methoxyethyl)amino]-6-[4-(trifluoromethyl)phenyl]-4-pyrimidinyl]oxy]-2(1H)-quinoxalinone. Grades: ≥97% by HPLC. CAS No. 939040-79-6. Molecular formula: C22H19F3N6O3. Mole weight: 472.42. | |
| AMG232 | AMG232 is an extremely potent MDM2 inhibitor with remarkable pharmacokinetic properties and in vivo antitumor activity in the SJSA-1 osteosarcoma xenograft model (ED50 = 9.1 mg/kg). AMG232 is currently under clinical development. Synonyms: AMG-232; AMG 232. Grades: 0.98. CAS No. 1352066-68-2. Molecular formula: C28H35Cl2NO5S. Mole weight: 568.55. | |
| AMG319 | AMG319 is a potent and selective PI3Kδ kinase inhibitor with IC 50 of 18 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1608125-21-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12948. | |
| AMG319 | AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity over other PI3Ks. Phase 2. Synonyms: AMG319; AMG-319; AMG 319; ACP319; ACP-319; ACP 319. Grades: 98%. CAS No. 1608125-21-8. Molecular formula: C21H16FN7. Mole weight: 385.4. | |
| AMG 333 | AMG 333 is a potent and highly selective TRPM8 antagonist with an IC50 of 13 nM for hTRPM8 and IC50 of 20 nM for rTRPM8, which displays high selectivity over other TRP channels (IC50>20 uM, TRPV1/V3/V4/A1). AMG-333 was well-tolerated in 28 day rat and dog preclinical safety studies and advanced to Phase 1 human clinical trials. Synonyms: 6-[[[ (S) - (3-Fluoro-2-pyridinyl) [3-fluoro-4- (trifluoromethoxy) phenyl]methyl]amino]carbonyl]-3-pyridinecarboxylic acid. Grades: ≥98% by HPLC. CAS No. 1416799-28-4. Molecular formula: C20H12F5N3O4. Mole weight: 453.33. | |
| AMG-337 | AMG 337 is an orally bioavailable inhibitor of the proto-oncogene c-Met with potential antineoplastic activity. c-Met inhibitor AMG 337 selectively binds to c-Met, thereby disrupting c-Met signal transduction pathways. Synonyms: AMG337; AMG-337; AMG 337. Grades: 98%. CAS No. 1173699-31-4. Molecular formula: C23H22FN7O3. Mole weight: 463.47. | |
| AMG-337 | AMG-337 is a potent, orally active, selective MET kinase inhibitor with IC 50 values of 1, 1, 4.7, 5, 21.5, 1077 and >4000 nM of WT MET, H1094R MET, M1250T MET, HGF-stimulated pMET (PC3 cells) MET, V1092I MET, Y1230H MET, and D1228H MET, respectively. AMG 337 inhibits the phosphorylation of MET and downstream effectors in MET-amplified cancer cell lines, resulting in an inhibition of MET-dependent cell proliferation and induction of apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1173699-31-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-18696. | |
| AMG 369 | This active molecular is a S1P1/S1P5 agonist with limited activity at S1P3. AMG 369 has no activity at S1P2 and S1P4. AMG-369 is shown to reduce blood lymphocyte counts 24 hours postdose with dosed orally at 0.1 mg/kg. Till Jun 2016, no recent reports of development identified for preclinical development in Multiple-sclerosis in USA were published yet. Uses: Multiple sclerosis. Synonyms: AMG-369; AMG 369; AMG369; KB-74649; KB74649; KB 74649. 1-[[3-fluoro-4-[6-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]phenyl]methyl]azetidine-3-carboxylicacid; ZINC216149127;1202073-26-4. Grades: 98%. CAS No. 1202073-26-4. Molecular formula: C26H22FN3O2S. Mole weight: 459.54. | |
| AMG-3969 | AMG-3969 is a potent and selective disruptor of glucokinase-glucokinase regulatory protein interaction (GK-GKRP). AMG-3969 can modulate the blood glucose levels in rodent models of diabetes. Synonyms: 2-[4-[(2S)-4-(6-aminopyridin-3-yl)sulfonyl-2-prop-1-ynylpiperazin-1-yl]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol. Grades: 98% by HPLC. CAS No. 1361224-53-4. Molecular formula: C21H20F6N4O3S. Mole weight: 522.466. | |
| AMG-458 | AMG 458 is a potent c-Met inhibitor with Ki of 1 nM ~ 2.0 nM. AMG-458 was found to significantly inhibit tumor growth in the NIH3T3/TPR-Met and U-87 MG xenograft models with no adverse effect on body weight. Synonyms: AMG458; AMG 458; 1-(2-Hydroxy-2-methylpropyl)-N-[5-[(7-methoxyquinolin-4-yl)oxy]pyridin-2-yl]-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide; 2,3-Dihydro-1-(2-hydroxy-2-methylpropyl)-N-[5-[(7-methoxy-4-quinolinyl)oxy]-2-pyridinyl]-5-methyl-3-oxo-2-phenyl-1H-pyrazole-4-carboxamide. Grades: ≥98%. CAS No. 913376-83-7. Molecular formula: C30H29N5O5. Mole weight: 539.58. | |
| AMG-47a | AMG-47a is a potent inhibitor of Lck and T cell proliferation. It has anti-inflammatory activity (ED50 = 11 mg/kg) in the anti-CD3 induced production of IL-2 in mice. It displays subnanomolar inhibition against Lck, and low inhibition against other hard to inhibit kinases in several other in vitro assays. It effectively inhibits the JNK family of kinases including TYK2 at ~ 1.2 μM but well under 10 μM. It selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protein in cells. Uses: Amg-47a has anti-inflammatory activity. Synonyms: AMG-47a; AMG 47a; AMG47a; AMG-47; AMG 47; AMG47. 4-Methyl-3-[2-[[2-(4-morpholinyl)ethyl]amino]-6-quinazolinyl]-N-[3-(trifluoromethyl)phenyl]benzamide. Grades: 95%. CAS No. 882663-88-9. Molecular formula: C29H28F3N5O2. Mole weight: 535.56. | |
| AMG 487 | AMG 487 is a CXCR3 antagonist that inhibits cell migration and metastasis. Synonyms: AMG-487; AMG 487; AMG487. Benzeneacetamide, N-((1R)-1-(3-(4-ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl)ethyl)-N-(3-pyridinylmethyl)-4-(trifluoromethoxy)-; N-[(1R)-1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluorome. CAS No. 473719-41-4. Molecular formula: C32H28F3N5O4. Mole weight: 603.59. | |
| AMG510 | AMG-510 is a potent KRAS G12C covalent inhibitor with potential antineoplastic activity. At the 2019 World Conference on Lung Cancer (WCLC), Amgen declared the efficacy of AMG 510 for treating non-small cell lung cancer (NSCLC) with KRAS G12 C-mutated solid tumors. Amgen also announced prospective directions for AMG510 through academic scholars and reports the few limitations on official drug release as evidence for potential investors to consider the value of AMG 510. Synonyms: AMG 510; AMG-510; Sotorasib. Grades: ≥98%. CAS No. 2252403-56-6. Molecular formula: C30H30F2N6O3. Mole weight: 560.59. | |
| AMG-510 | AMG-510 Inhibitor. Uses: Scientific use. Product Category: T8684. CAS No. 2296729-00-3. |  |
| AMG510 racemate | AMG510 is a potent KRAS G12C covalent inhibitor with potential antineoplastic activity. At the 2019 World Conference on Lung Cancer (WCLC), Amgen declared the efficacy of AMG510 for treating non-small cell lung cancer (NSCLC) with KRAS G12 C-mutated solid tumors. Amgen also announced prospective directions for AMG510 through academic scholars and reports the few limitations on official drug release as evidence for potential investors to consider the value of AMG510. Uses: Immune checkpoint inhibitors. Synonyms: AMG-510 racemate; AMG 510 racemate; Sotorasib racemate. CAS No. 2296729-00-3. Molecular formula: C30H30F2N6O3. Mole weight: 560.59. | |
| AMG 517 | AMG 517 is a potent and selective vanilloid receptor-1 ( TRPV1 ) antagonist with an IC 50 of 0.5 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 659730-32-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10634. | |
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