A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Antrimycin is a peptide antibiotic produced by Streptomyces xanthocidicus MG125-CF1. Antrimycin A has anti-Mycobamrimn smegmatis (Mycobamrimn smegmatis) and human Mycobacterium tuberculosis H37 Rv activity, and also has an effect on rifampicin and capreomycin-resistant bacteria. Synonyms: Antrimycin; Cirratiomycin B; L-Serine, 2-(hydroxymethyl)seryl-L-alanyl-L-erythro-alpha,beta-diaminobutyryl-L-2,3,4,5-tetrahydro-3-pyridazinecarbonyl-L-alanyl-(E)-2,3-didehydroisoleucyl-. Grades: >98%. CAS No. 80801-26-9. Molecular formula: C28H47N9O11. Mole weight: 685.72.
Antrimycin B
Antrimycin is a peptide antibiotic produced by Streptomyces xanthocidicus MG125-CF1. Synonyms: 2-(Hydroxymethyl)-Ser-L-Ala-[(3S)-3-amino-L-Abu-]-1,6-didehydro-L-Pyz-L-Abu-2,3-didehydro-L-Ile-L-Ser-OH. CAS No. 82518-60-3. Molecular formula: C29H49N9O11. Mole weight: 699.75.
Antrimycin C
Antrimycin is a peptide antibiotic produced by Streptomyces xanthocidicus MG125-CF1. CAS No. 82534-66-5. Molecular formula: C30H51N9O11. Mole weight: 713.78.
Antroquinonol
Antroquinonol ((+)-Antroquinonol), a ubiquinone derivative from the mushroom Antrodia camphorata , has hepatoprotective, anti-inflammatory, and anti-cancer effects [1]. Antroquinonol can be used for the research of colon cancer [2]. Antroquinonol reduces oxidative stress by enhancing the Nrf2 signaling pathway and inhibits inflammation and sclerosis in focal segmental glomerulosclerosis mice [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-Antroquinonol. CAS No. 1010081-09-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-19893.
ANTS
ANTS is a fluorescent dye. ANTS and DPX are encapsulated in liposomes can be an effective approach for measuring membrane leakage [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 5398-34-5. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-D0789.
Anwuligan
Anwuligan. Group: Biochemicals. Alternative Names: Macelignan; Calophyn. Grades: Plant Grade. CAS No. 107534-93-0. Pack Sizes: 20mg. Molecular Formula: C20H24O4, Molecular Weight: 328.402. US Biological Life Sciences.
ANX-510 is a folate-based biomodulator with potential antineoplastic activity. 5,10-methylenetetrahydrofolate (MTHF) stabilizes the covalent binding of the fluorouracil metabolite 5-5-fluoro-2'-deoxyuridine-5'-O-monophosphate (FdUMP) to its target enzyme, thymidylate synthase, which results in inhibition of thymidylate synthase, depletion of thymidine triphosphate (TTP), a necessary constituent of DNA, and tumor cell death. Synonyms: 5,10-Methylenetetrahydrofolic acid; 5,10-Methylene-tetrahydrofolate; Tetrahydromethylenefolate; N-{4-[3-amino-1-oxo-1,2,5,6,6a,7-hexahydroimidazo[1,5-f]pteridin-8(9H)-yl]benzoyl}-L-glutamic acid. CAS No. 3432-99-3. Molecular formula: C20H23N7O6. Mole weight: 457.44.
Anziaic acid
It is produced by the strain of Stereocaulon ramulosum. Synonyms: NSC 766393; 6-Hydroxy-4-[(2,4-dihydroxy-6-pentylbenzoyl)oxy]-2-pentylbenzoic acid; 2,4-Dihydroxy-6-pentylbenzoic acid 4-carboxy-3-hydroxy-5-pentylphenyl ester; 4-(2,4-Dihydroxy-6-pentylbenzoyloxy)-6-pentylsalicylic acid; Benzoic acid, 2,4-dihydroxy-6-pentyl-, 4-carboxy-3-hydroxy-5-pentylphenyl ester; 4-Carboxy-3-hydroxy-5-pentylphenyl 2,4-dihydroxy-6-pentylbenzoate; Anzic acid. Grades: ≥98% by HPLC. CAS No. 641-68-9. Molecular formula: C24H30O7. Mole weight: 430.49.
AOD9604
AOD 9604 is a modified fragment of human growth hormone (hGH) that is originally developed as an anti-obesity drug. AOD 9604 is formulated as the injection for weight loss, muscle building and so on. Synonyms: L-tyrosyl-L-leucyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-cysteinyl-L-arginyl-L-seryl-L-valyl-L-alpha-glutamyl-glycyl-L-seryl-L-cysteinyl-glycyl-L-phenylalanine (7->14)-disulfide; AOD 9604; LAT 8881; L-Phenylalanine, L-tyrosyl-L-leucyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-cysteinyl-L-arginyl-L-seryl-L-valyl-L-α-glutamylglycyl-L-seryl-L-cysteinylglycyl-, cyclic (7?14)-disulfide. CAS No. 221231-10-3. Molecular formula: C78H123N23O23S2. Mole weight: 1815.08.
AOD9604 acetate
AOD9604 acetate is a modified fragment of human growth hormone (hGH) that was originally developed as an anti-obesity drug. AOD9604 is formulated as the injection for weight loss, muscle building and so on. Synonyms: AOD-9604 acetate; AOD 9604 acetate; H-Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe-OH.CH3CO2H (Disulfide bridge: Cys7-Cys14); L-tyrosyl-L-leucyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-cysteinyl-L-arginyl-L-seryl-L-valyl-L-alpha-glutamyl-glycyl-L-seryl-L-cysteinyl-glycyl-L-phenylalanine (7->14)-disulfide acetic acid; LAT 8881 acetate. Grades: ≥95%. Molecular formula: C80H127N23O25S2. Mole weight: 1875.15.
AOH1160-1LE
AOH1160-1LE is a derivative of AOH1160, a small-molecule PCNA inhibitor. AOH1160-1LE was shown to bind into the PCNA-interacting protein-box (PIP-box). Molecular formula: C28H24N2O5. Mole weight: 468.50.
AOH1996
AOH1996 is a small-molecule PCNA inhibitor that enhances the interaction between PCNA and the largest subunit of RNA polymerase II, RPB1, and dissociates PCNA from actively transcribed chromatin regions, while inducing DNA double-stranded breaks in a transcription-dependent manner. AOH1996 was identified as a selective chemotherapeutic. Synonyms: AOH 1996; AOH-1996; NSC789796; NSC-789796. CAS No. 2089314-64-5. Molecular formula: C26H22N2O4. Mole weight: 426.46.
AOH1996-1LE
AOH1996-1LE is a derivative of AOH1160, a small-molecule PCNA inhibitor. AOH1996-1LE was shown to bind into the PCNA-interacting protein-box (PIP-box).
AOP
AOP. Group: Biochemicals. Alternative Names: 7-(Azabenzotriazol-1-yl)oxy tris (dimethylamino) phosphonium hexafluorophosphate. Grades: Highly Purified. CAS No. 156311-85-2. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C11H21F6N7OP2. US Biological Life Sciences.
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Aorta, Bovine
Aorta, Bovine. Group: Biologicals. Grades: Tissue. Pack Sizes: 10Ea. US Biological Life Sciences.
Worldwide
Aorta, Rabbit
Aorta, Rabbit. Group: Biologicals. Grades: Tissue. Pack Sizes: 50Ea. US Biological Life Sciences.
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Aortic Artery Endothelial Cells, Human (Frozen)
Passage 3 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplement, is recommended for culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences.
Worldwide
Aortic Artery Endothelial Cells, Human (T-25 flask)
Passage 3 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplement, is recommended for culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences.
Worldwide
AOZ-[d4]
AOZ-[d4] is the labelled analogue of AOZ, which is a metabolite of Furazolidone. Synonyms: AOZ-d4; 3-Amino-2-oxazolidinone-d4; 3-Amino-1,3-oxazolidin-2-one-d4; NSC 111187-d4; NSC 196570-d4; NSC 38250-d4; Vetranal-d4. Grades: ≥97%; ≥97% atom D. CAS No. 1188331-23-8. Molecular formula: C3H2D4N2O2. Mole weight: 106.12.
AP 1189
AP 1189 exhibits biased agonistic activity towards the melanocortin 1 and melanocortin 3 receptors. Synonyms: Hydrazinecarboximidamide, 2-[(2E)-3-[1-(2-nitrophenyl)-1H-pyrrol-2-yl]-2-propen-1-ylidene]-, acetate (1:1), (2E)-; AP1189; AP-1189; Resomelagon acetate; (E)-2-((E)-3-(1-(2-nitrophenyl)-1H-pyrrol-2-yl)allylidene)hydrazine-1-carboximidamide acetate. Grades: ≥95%. CAS No. 1809420-72-1. Molecular formula: C14H14N6O2.C2H4O2. Mole weight: 358.35.
AP1189 acetate
AP1189 is a biased agonist at receptors MC1 and MC3. AP1189 reduced cytokine release, an effect reliant on both MC1 and MC3 as evident from the use of Mc1r(-/-) and Mc3r(-/-) macrophages. No melanogenesis was induced by AP1189 in B16-F10 melanocytes. In vivo, oral AP1189 elicited anti-inflammatory actions in peritonitis and, upon administration at the peak of inflammation, accelerated the resolution phase by ~3-fold. Group: Agonists. Alternative Names: AP-1189; AP 1189; AP1189; AP1189 acetate. CAS No. 959850-74-9. Molecular formula: C16H18N6O4. Mole weight: 358.36. Appearance: Solid powder. Purity: >98%. IUPACName: (E)-N-[trans-3-{1-(2-Nitrophenyl)-1H-pyrrol-2-yl} allylidenamino]guanidinium acetate. Canonical SMILES: NC (N/N=C/C=C/C1=CC=CN1C2=CC=CC=C2[N+] ([O-])=O)=N. CC (O)=O. Catalog: ACM959850749.
AP14145 hydrochloride
AP14145 hydrochloride is a potent K Ca 2 (SK) channel negative allosteric modulator with an IC 50 of 1.1 μM for K Ca 2.2 (SK2) and K Ca 2.3 (SK3) channels. AP14145 hydrochloride inhibition strongly depends on two amino acids, S508 and A533 in the channel. AP14145 hydrochloride prolonged atrial effective refractory period (AERP) in rats and demonstrates antiarrhythmic effects in a Vernakalant-resistant porcine model of atrial fibrillation (AF) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2387505-59-9. Pack Sizes: 5 mg. Product ID: HY-120355A.
Ap 159
Heterocyclic Organic Compound. CAS No. 129592-83-2. Catalog: ACM129592832.
AP18
AP18 is a selective Transient receptor potential A1(TRPA1) channel blocker which reversibly inhibits TRPA1 with IC50 values of 3.1 and 4.5 μM at human and mouse respectively. It has been used to study TRPA1 signaling in mice and rats as well as in vitro. It blocks the transient receptor potential ankyrin 1 receptors and can reduce chronic pain associated with arthritis. It also blocks cinnamaldehyde-induced nociception in vivo and blocks cold- and mustard oil-induced activation of mouse TRPA1 but not capsaicin-induced activation. It reverses CFA-induced mechanical hyperalgesia in mice. Uses: Ap18 blocks the transient receptor potential ankyrin 1 receptors and can reduce chronic pain associated with arthritis. Synonyms: AP-18; AP 18; AP18. 4-(4-Chlorophenyl)-3-methylbut-3-en-2-oxime;AP-18;4-(4-Chlorophenyl)-3-methyl-3-buten-2-oneoxime;(NE)-N-[(Z)-4-(4-chlorophenyl)-3-methylbut-3-en-2-ylidene]hydroxylamine;(2E,3E)-4-(4-chlorophenyl)-3-methylbut-3-en-2-one oxime. Grades: 98%. CAS No. 55224-94-7. Molecular formula: C11H12ClNO. Mole weight: 209.67.
AP 18
AP 18. Group: Biochemicals. Grades: Purified. CAS No. 55224-94-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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AP-18
AP-18. Group: Biochemicals. Alternative Names: 4-(4-Chlorophenyl)-3-methyl-3-buten-2-one Oxime. Grades: Highly Purified. CAS No. 55224-94-7. Pack Sizes: 5mg. Molecular Formula: C11H12ClNO, Molecular Weight: 209.67. US Biological Life Sciences.
Worldwide
AP1867
AP1867 is a precursor for the dTAG system which pairs a novel degrader of FKBP12(F36V) with expression of FKBP12(F36V) in-frame with a protein of interest. Synonyms: AP 1867; 3- (3- ( (R) -3- (3, 4-Dimethoxyphenyl) -1- ( ( (S) -1- ( (S) -2- (3, 4, 5-trimethoxyphenyl) butanoyl) -piperidine-2-carbonyl) oxy) propyl) phenoxy) propanoic acid. CAS No. 195514-23-9. Molecular formula: C38H47NO11. Mole weight: 693.78.
AP1867-2-(carboxymethoxy)
AP1867-2-(carboxymethoxy), the AP1867 (a synthetic FKBP12F36V-directed ligand) based moiety, binds to CRBN ligand via a linker to form dTAG molecules. It is a ligand and a binder that contributes to the enhancer-promoter structural interactions of DNA elements. Synonyms: PROTAC FKBP12-binding moiety 2; 2-(2-((R)-3-(3,4-Dimethoxyphenyl)-1-(((S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carbonyl)oxy)propyl)phenoxy)acetic acid; 2-Piperidinecarboxylic acid, 1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-, (1R)-1-[2-(carboxymethoxy)phenyl]-3-(3,4-dimethoxyphenyl)propyl ester, (2S)-; Ortho-AP1867. Grades: ≥96%. CAS No. 2230613-03-1. Molecular formula: C38H47NO11. Mole weight: 693.78.
AP1903
AP1903 is a lipid-permeable tacrolimus analogue with homodimerizing activity. Dimerizer drug AP1903 homodimerizes an analogue of human protein FKBP12 (Fv) which contains a single acid substitution (Phe36Val) so that AP1903 binds to wild-type FKBP12 with 1000-fold lower affinity. Synonyms: AP1903; AP 1903; AP-1903; Rimiducid. Grades: 0.98. CAS No. 195514-63-7. Molecular formula: C78H98N4O20. Mole weight: 1411.63.
AP20187
Systemic AP20187 administration results in time-dependent LFv2IRE tyrosine phosphorylation and activation of the insulin signaling pathway in both liver and muscle of AAV-treated NOD mice. AP20187 stimulation significantly increases hepatic glycogen content and muscular glucose uptake similarly to insulin. The homodimerizer has been widely used to study signal transduction pathways (by inducing oligomerization of cell surface receptor proteins), but it can be used to induce the activity/re-localization of any protein that is affected by oligomerization. To test the role of homodimerization in kinase activation, we constructed a fusion protein consisting of the SLK catalytic domain (amino acids 1-373) and a modified FK506 binding protein, Fv (Fv-SLK 1-373). Addition of AP20187 (an analog of FK506) enhanced the homodimerization of Fv-SLK 1-373. Synonyms: AP 20187; AP-20187. Grades: >98%. CAS No. 195514-80-8. Molecular formula: C82H107N5O20. Mole weight: 1482.75.
AP219
AP219 is a control compound for AP39, which contains the triphenylphosphonium scaffold but lacking the H2 S-releasing portion. AP39 is a compound used to increase the levels of hydrogen sulfide (H2S) within mitochondria. Synonyms: (9-Carboxynonyl)triphenylphosphonium; 779282-36-9; AP219; 9-carboxynonyl(triphenyl)phosphanium; (9-Carboxynonyl)triphenyl-phosphonium; CHEMBL3582497; SCHEMBL20859564; AKOS040755143; (9-Carboxynonyl)triphenyl-phosphonium Bromide (>90%). Grades: ≥98%. CAS No. 779282-36-9. Molecular formula: C28H34O2P. Mole weight: 433.6.
AP-22161
AP-2216, designed to bind selectively to the Src SH2 domain by targeting a cysteine residue, has the potential to be further developed for treating osteoporosis. Synonyms: 4-[(2S)-2-acetamido-3-[[(5S)-3-carbamoyl-2-(cyclohexylmethoxy)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-yl]amino]-3-oxopropyl]-2-formylbenzoic acid; AP-22161; AP 22161; AP22161; SCHEMBL7243003; G7VE62573J; UNII-G7VE62573J. Grades: >98%. CAS No. 268741-42-0. Molecular formula: C32H39N3O7. Mole weight: 577.67.
AP2238
AP2238 is a inhibitor of both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation. Uses: Cholinesterase inhibitors. Synonyms: AP-2238; AP 2238; AP2238; CHEMBL75121; UNII-545225E0BC; BDBM10949; DNC007569; 2H-1-Benzopyran-2-one, 6, 7-dimethoxy-3- (4- ( (methyl (phenylmethyl)amino)methyl)phenyl)-; 3-[4- (N-Benzyl-N-methylaminomethyl)phenyl]-6, 7-dimethoxy-2H-1-benzopyran-2-one. Grades: 98%. CAS No. 553681-56-4. Molecular formula: C26H25NO4. Mole weight: 415.48.
AP-22408
AP-22408, a Src tyrosine kinase inhibitor, is an orally bioavailable phosphotyrosine mimic resulting from a structurebased design. Synonyms: [4-[(2S)-2-acetamido-3-[[(5S)-3-carbamoyl-2-(cyclohexylmethoxy)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-yl]amino]-3-oxopropyl]-2-phosphonophenyl]phosphonic acid; AP-22408; AP 22408; AP22408; UNII-3U3L5QR4KV; CC1; AC1L9I7C; 3U3L5QR4KV; SCHEMBL7245569. Grades: >98%. CAS No. 268741-43-1. Molecular formula: C30H41N3O10P2. Mole weight: 665.61.
AP23464
AP23464 is a potent adenosine 5'-triphosphate (ATP)-based inhibitor of Src and Abl kinases. It displays antiproliferative activity against a human CML cell line and Bcr-Abl-transduced Ba/F3 cells with an IC50=14 nM. Synonyms: AP-23464; AP 23464; (4-((2-cyclopentyl-9-(3-hydroxyphenethyl)-9H-purin-6-yl)amino)phenyl)dimethylphosphine oxide. Grades: >98%. CAS No. 845895-51-4. Molecular formula: C30H38N5O2P. Mole weight: 475.53.
AP23846
AP23846 is a potent c-Src kinase inhibitor (IC50 approximately 0.5 nmol/L in vitro, approximately 10-fold more potent than PP2, the most widely used commercially available Src family kinase inhibitor). Synonyms: AP-23846; (4-((2-cyclopentyl-9-ethyl-9H-purin-6-yl)amino)phenyl)dipropylphosphine oxide. Grades: >98%. CAS No. 878654-51-4. Molecular formula: C20H16FN3O2. Mole weight: 439.53.
AP23848
AP23848 is a potent Bcr-Abl inhibitor. Synonyms: AP-23848; AP 23848; PF-562771; (4-((2-Cyclopentyl-9-(3-hydroxyphenethyl)-9H-purin-6-yl)amino)phenyl)dipropylphosphine oxide. Grades: >98%. CAS No. 834894-21-2. Molecular formula: C13H15N5O6. Mole weight: 531.63.
AP 24534
AP 24534. Group: Biochemicals. Grades: Purified. CAS No. 943319-70-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
AP-24600
AP-24600 is a bio-active chemical, but no detailed information has been published yet. Synonyms: AP-24600; AP 24600; AP24600; DA-12847; KB-310048; DA 12847; KB 310048; DA12847; KB310048; UNII-OZ477A282R; OZ477A282R;3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic acid. Grades: 98%. CAS No. 1300690-48-5. Molecular formula: C16H11N3O2. Mole weight: 277.28.
AP 26113
AP 26113. Group: Biochemicals. Grades: Highly Purified. CAS No. 1350848-43-9. Pack Sizes: 1mg. Molecular Formula: C26H34ClN6O2P, Molecular Weight: 529.01. US Biological Life Sciences.
Worldwide
AP-26113
AP26113 is an orally available inhibitor of receptor tyrosine kinases anaplastic lymphoma kinase (ALK) and the epidermal growth factor receptor (EGFR) with potential antineoplastic activity. AP26113 binds to and inhibits ALK kinase and ALK fusion proteins as well as EGFR and mutant forms. AP26113 appears to overcome mutation-based resistance. ALK belongs to the insulin receptor superfamily and plays an important role in nervous system development. Synonyms: AP-26113; AP 26113; AP26113; (2-((5-chloro-2-((4-(4-(dimethylamino)piperidin-1-yl)-2-methoxyphenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide; AP26113-analog; AP-26113-analog; AP 26113-analog, Brigatinib-analog. Grades: 0.98. CAS No. 1197958-12-5. Molecular formula: C26H34ClN6O2P. Mole weight: 529.01.
AP2A
AP2A, a prized medication within the biomedical industry, has transcended the boundaries of healing, showcasing its versatility in treating numerous afflictions, including but not limited to, managing pain, alleviating inflammatory disorders, and thwarting cancer. Prized for its utmost efficacy, AP2A efficaciously binds and regulates the activity of specific enzymatic and protein molecules that initiate the cascade of these aforementioned conditions. With its potential for therapeutic use being exhaustively studied and researched, it stands as an invaluable asset in the biomedicine realm. Synonyms: P1-(5'-Adenosyl) P3-(5'-adenosyl) triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 85065-24-3. Molecular formula: C20H26N10O13P2 (free acid). Mole weight: 676.43 (free acid).
AP2Ribavirin
AP2Ribavirin, an antiviral drug, exerts its efficacy against the Hepatitis C virus (HCV) by curbing the replication of viral RNA through interference with RNA-dependent RNA polymerase. Coupled with other HCV drugs, AP2Ribavirin enhances therapeutic outcomes - serving as a frontline defense against this viral infection. Synonyms: 1,2,4-Triazole-3-carboxamide adenine dinucleotide, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C18H25N9O14P2 (free acid). Mole weight: 653.39 (free acid).
AP39
AP39 is a compound used to increase the levels of hydrogen sulfide (H2S) within mitochondria. It is also used as a photosensitizer, hydrogen sulfide donor, thioredoxin inhibitor or nitroxide combination use in photodynamic therapy. It consists of a mitochondria-targeting motif (triphenylphosphonium) coupled to an H2S-donating moiety (dithiolethione) by an aliphatic linker. It stimulates mitochondrial electron transport and improves cellular bioenergetic function at lower concentrations (30-100 nM), while having an inhibitory effect at 300 nM. Grades: ≥95%. CAS No. 1429173-57-8. Molecular formula: C37H38O2PS3. Mole weight: 641.9.
AP3A - lyophilized
AP3A - lyophilized is a biomedical product that holds immense value in understanding the complex aspects of liver-specific gene expression alongside the role of essential extracellular ATP. It has a proven track record in liver disease research and liver cancer. AP3A's profound potency lies in activating P2Y purinergic receptors, thus leading to a significant surge in ATP stimulation within liver cells. AP3A's ever-efficient lyophilized form guarantees long-term storage and easy usability for laboratory experiments. Synonyms: (ApppA); P1-(5'-Adenosyl) P3-(5'-adenosyl) triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 5959-90-0. Molecular formula: C20H27N10O16P3 (free acid). Mole weight: 756.41 (free acid).
AP3A - solution
AP3A solution, a biochemical product entrenched in biomedical industry, commands center stage in studying purinergic signaling pathways, amongst others. This efficacious prodigy, a mainstay in academic research labs, abets multifarious research endeavors including, but not limited to, curing autoimmune disorders, neurodegenerative diseases, and cancer. AP3A solution, sourced from different research chemical providers, beckons an important armamentarium for scientists and researchers aiming to unearth the intricacies of cellular signaling pathways. Synonyms: (ApppA); P1-(5'-Adenosyl) P3-(5'-adenosyl) triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H27N10O16P3 (free acid). Mole weight: 756.41 (free acid).
AP3G (A cap)
AP3G (A cap) is a non-functional cap analog used in the synthesis of mRNA to estimate the level of cap-independent translation. Synonyms: (ApppG); P1-(5'-Adenosyl) P3-(5'-guanosyl) triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H27N10O17P3 (free acid). Mole weight: 772.41 (free acid).
AP3 (Nic)
AP3 (Nic), a powerful and exclusive inhibitor of phosphodiesterase 10A (PDE10A), which has been extensively investigated for its probable therapeutic usage in motor and cognitive deficits observed in Parkinson's disease and schizophrenia, exhibits neurosignaling pathways modulation characteristics. Synonyms: P1-(5'-Adenosyl) P3-[5'-(1-β D-Ribofuranosyl-nicotinamide)] triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C21H28N7O17P3 (free acid). Mole weight: 743.41 (free acid).
AP4
AP4 is a scientifically advanced compound, standing as an exemplary research for neurodegenerative ailments, including the formidable Parkinson's disease. With remarkable efficacy, it ensnares the unruly culprit, L-alpha-amino-4-hydroxy-2,3,5-trichlorobenzene (ATCB) which is an influential enzyme breaching dopamine's metabolic fortress. Synonyms: (Adenosine-5'-tetraphosphate); Adenosine-5'-tetraphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 1062-98-2. Molecular formula: C10H17N5O16P4 (free acid). Mole weight: 587.16 (free acid).
AP4 (8-Iodo-G)
AP4 (8-Iodo-G) is a chemical compound utilized in the biomedical industry for research purposes. Studies suggest that it may have applications in treating neurological disorders such as epilepsy, as well as potential antitumor and antimicrobial effects. Further research is ongoing to determine its full therapeutic potential. Synonyms: (AP4(8I-G)); P1-(5'-Adenosyl) P4-[5'-(8-iodo)-guanosyl] tetraphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H27IN10O20P4 (free acid). Mole weight: 978.28 (free acid).
AP4A
AP4A is a signal molecule for DNA replication in mammalian cells. AP4A is used as a primer for oligoadenylate synthesis catalyzed by interferon-inducible 2-5A synthetase. AP4A is an inhibitor of eosinophil-derived neurotoxin (EDN). Uses: Ap4a is an inhibitor of eosinophil-derived neurotoxin (edn). Synonyms: (AppppA); P1-(5'-Adenosyl) P4-(5'-adenosyl) tetraphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 5542-28-9. Molecular formula: C20H28N10O19P4 (free acid). Mole weight: 836.39 (free acid).
Ap4C
Ap4C, a nucleotide analogue, boasts the extraordinary capability of selectively activating purinergic receptor P2X receptors. Its potential applications are broad-spanning from treating inflammatory diseases to chronic pain and cancer, all of which are associated with abnormal purinergic signaling. Synonyms: P1- (5'- Adenosyl)- P4- (5'- cytidyl)- tetraphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 1352921-13-1. Molecular formula: C19H28N8O20P4 (free acid). Mole weight: 812.4 (free acid).
AP4dT
AP4dT is a novel and auspicious antiviral drug exhibiting compelling efficacy against HCV by suppressing viral RNA polymerase enzyme, thereby restraining viral genome replication. Preclinical studies suggest that AP4dT could be a potential pan-genotypic therapeutic candidate for HCV, capable of treating both genotype 1 and 3 infections alike. Synonyms: P1-(5'-Adenosyl) P4-[5'-(2'-deoxy-thymidyl)] tetraphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. CAS No. 13457-68-6. Molecular formula: C20H29N7O20P4 (free acid). Mole weight: 811.38 (free acid).
AP4G
AP4G is a state-of-the-art biomedical compound meticulously used for studying an array of formidable neurological afflictions such as Alzheimer's, Parkinson's and epilepsy. Synonyms: (AppppG); P1-(5'-Adenosyl) P4-(5'-guanosyl) tetraphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. CAS No. 10527-46-5. Molecular formula: C20H28N10O20P4 (free acid). Mole weight: 852.39 (free acid).
AP4U
AP4U, an innovative biomedical intervention, revolutionizes the therapeutic landscape in Parkinson's disease management. With extraordinary efficacy, this groundbreaking product exerts a profound influence on pyridoxal kinase, effectively curbing the transformation of pyridoxal into pyridoxal 5'-phosphate. Through this intricate modulation, AP4U remarkably ameliorates the debilitating symptoms of Parkinson's, presenting itself as an indispensable therapeutic remedy. Synonyms: P1-(5'-Adenosyl) P4-(5'-uridyl) tetraphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 10527-48-7. Molecular formula: C19H27N7O21P4 (free acid). Mole weight: 813.35 (free acid).
AP5 (8-Iodo-G)
AP5 (8-Iodo-G) is a highly potent biomedical compound, diligently functioning as a discriminating antagonist specifically modulating the AMPA receptor, thereby efficaciously facilitating the exploration and innovation of novel therapeutic modalities directed towards debilitating ailments. Synonyms: (AP5(8I-G)); P1-(5'-Adenosyl) P5-[5'-(8-iodo)-guanosyl] pentaphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H28IN10O23P5 (free acid). Mole weight: 1058.26 (free acid).
AP5A
AP5A is an adenosine A2A receptor antagonist used for studying Parkinson's disease. Uses: Vasoconstrictor agents. Synonyms: P1-(5'-Adenosyl) P5-(5'-adenosyl) pentaphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 41708-91-2. Molecular formula: C20H29N10O22P5 (free acid). Mole weight: 916.37 (free acid).
AP5dT
AP5dT is an exceptional synthetic nucleoside analog, facilitating the exploration of intricate DNA replication and repair mechanisms. aP5dT can amplify the comprehension of virally-inflicted ailments (e.g., HIV, herpes) as well as diverse DNA-centric maladies. Synonyms: P1-(5'-Adenosyl) P5-[5'-(2'-deoxy-thymidyl)] pentaphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. CAS No. 103137-88-8. Molecular formula: C20H30N7O23P5 (free acid). Mole weight: 891.36 (free acid).
AP5G
AP5G, a peptide analog, stands as a beacon of hope in the biomedical research realm, wielding its anti-tumor and anti-inflammatory properties. Heralding the growth and proliferation inhibition of cancer cells, especially those found in breast and lung cancer, AP5G adds another feather to its cap as an exquisitely effective anti-inflammatory agent, bestowing it with the ability to be contemplated as a potential panacea for maladies like rheumatoid arthritis and inflammatory bowel disease. Further, the possibility of assimilating AP5G into neurological disorder treatment regimes represents its multifaceted nuance, with exhaustive studies indicating its potential neuroprotective effects, making it a potential cog in the wheel to combat Alzheimer's disease. Synonyms: P1-(5'-Adenosyl) P5-(5'-guanosyl) pentaphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. CAS No. 56983-24-5. Molecular formula: C20H29N10O23P5 (free acid). Mole weight: 932.37 (free acid).
AP5U, a potent and selective inhibitor of phosphodiesterase-5 (PDE5), has emerged as a viable therapeutic intervention for erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). This synthetic molecule relaxes the smooth muscles lining blood vessels, augmenting blood perfusion to the penile or pulmonary vasculature, and enhancing exercise capacity in PAH patients. AP5U promises to offer a ray of hope for those suffering from these debilitating health disorders, revolutionizing the way we perceive and treat ED and PAH in contemporary medicine. Synonyms: P1-(5'-Adenosyl) P5-(5'-uridyl) pentaphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 56983-25-6. Molecular formula: C19H28N7O24P5 (free acid). Mole weight: 893.33 (free acid).
AP-6
AP-6 is a selective inhibitor of TMEM175 with activity in modulating lysosomal function. Acute inhibition of TMEM175 by AP-6 increases lysosomal macromolecular catabolism, thereby accelerating macrophage and other digestive processes. AP-6 may be used in Parkinson's disease research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1369963-51-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161949.
AP6A
AP6A is a potent vasoconstrictor. Synonyms: P1-(5'-Adenosyl) P6-(5'-adenosyl) hexaphosphate; Diadenosine hexaphosphate; P1,P6-di(Adenosine-5')hexaphosphate; Diadenosine 5',5''''-P1,P6-hexaphosphate; AppppppA; Ap(6)A; Adenosine-(5')-hexaphospho-(5')-adenosine; Adenosine 5'-hexaphosphate 5'-ester with adenosine; P1,P6-Bis(5'-adenosyl)hexaphosphate. Grades: ≥95% by HPLC. CAS No. 56983-23-4. Molecular formula: C20H30N10O25P6. Mole weight: 996.35.
AP6A Sodium salt
AP6A Sodium salt is the salt of AP6A, a potent vasoconstrictor. Synonyms: P1-(5'-Adenosyl) P6-(5'-adenosyl) hexaphosphate Sodium salt; Diadenosine hexaphosphate Sodium salt; P1,P6-di(Adenosine-5')hexaphosphate Sodium salt; Diadenosine 5',5''''-P1,P6-hexaphosphate Sodium salt; AppppppA Sodium salt; Ap(6)A Sodium salt; Adenosine-(5')-hexaphospho-(5')-adenosine Sodium salt; Adenosine 5'-hexaphosphate 5'-ester with adenosine Sodium salt; P1,P6-Bis(5'-adenosyl)hexaphosphate Sodium salt. Grades: ≥95% by HPLC. Molecular formula: C20H30N10O25P6 (free acid). Mole weight: 996.35 (free acid).
AP 811
AP 811 is a selective atrial natriuretic peptide clearance receptor (ANP-CR, NPR3) antagonist with a K i of 0.48 nM. AP 811 displays >20000-fold selectivity for NPR3 over NPR1. AP 811 abolishes ANP-induced pump stimulation [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 124833-45-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1419.
AP 811
AP 811 has been found to be an NPR3 antagonist and could restrain Na+/K+ pump activity in rabbit ventricular cardiomyocytes. Synonyms: N2-[[4-[ (2-Naphthalenylcarbonyl) amino]phenyl]acetyl]-L-arginyl-L-isoleucyl-L-α -aspartyl-N-[ (2S) -2-methylbutyl]-L-argininamide; (S) -N2-[[4-[ (2-Naphthalenylcarbonyl) amino]phenyl]acetyl]-L-arginyl-L-isoleucyl-L-α -aspartyl-N- (2-methylbutyl) -L-argininamide; AP811; AP-811. Grades: ≥95% by HPLC. CAS No. 124833-45-0. Molecular formula: C46H66N12O8. Mole weight: 915.09.
ApA
ApA is a nucleoside derivative prevalent in the biomedical sector, garnering significant attention due to its profound implications in research of viral infections. Synonyms: RNA Dinucleotide (5'?3'), Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H25N10O10P (free acid). Mole weight: 596.45 (free acid).
APA Amoxicillin Amide
APA Amoxicillin Amide is a derivative of Amoxicillin, which is an antibiotic used to treat a number of bacterial infections including middle ear infections, strep throat, pneumonia, skin infections, and urinary tract infections. Synonyms: N-(Penicillan-6-yl) amoxicillinamide; Amoxicillin EP Impurity L; Amoxicillin USP Related Compound L; 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[(2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-yl]carbonyl]amino]-3,3-dimeth yl-7-oxo-, (2S,5R,6R)-. Grades: 95%. CAS No. 1789703-32-7. Molecular formula: C24H29N5O7S2. Mole weight: 563.65.
APA Amoxicillin Amide
APA Amoxicillin Amide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug. Molecular Formula: C24H29N5O7S2, Molecular Weight: 563.65. US Biological Life Sciences.