A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Akt/protein kinase B (PKB) inhibitor. Binds the pleckstrin homology domain of Akt and blocks Akt membrane translocation. Inhibits EGF-induced kinase activity of Akt1, Akt2 and Akt3. Induces cell growt h arrest and apoptosis in human cancer cells expressing constitutively active Akt. Synonyms: API 1; API1; NSC177233; NSC 177233; NSC-177233; 4-Amino-5,6,7,8-tetrahydro-5-oxo-8-(beta-D-ribofuranosyl)pyrido[2,3-d]pyrimidine-6-carboxamide. Grades: >98%. CAS No. 36707-00-3. Molecular formula: C28H30FN5O2. Mole weight: 337.29.
API-2. Group: Biochemicals. Grades: Purified. CAS No. 35943-35-2. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Apicidin
Apicidin (OSI 2040) is a fungal metabolite, acts as an orally active histone deacetylase 7/8 ( HDAC7/8 ) inhibitor, with antiparasitic activity and a broad spectrum antiproliferative activity. Apicidin can be used for cancer research [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: OSI 2040. CAS No. 183506-66-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6735.
Apicidin
Apicidin is a cyclic peptide antibiotic with broad spectrum antiparasitic and antiprotozoan activity. Apicidin, a histone deacetylase inhibitor, is anti-angiogenic and induces apoptosis. A potent, cell permeable inhibitor of histone deacetylase (IC50 = 700 pM for parasitic histone deacetylase). Inhibits HeLa cell proliferation (IC50 = 50 - 100 nM) and induces the transcriptional activation of p21 (WAF1) in a reversible manner. Also prevents H-ras-induced invasive phenotype of MCF-10A cells possibly by down regulating MMP-2 in a reversible manner. Apicidin has antiproliferative activity on HeLa cells accompanied by cell arrest at the G1 phase. Apicidin induces selective changes in the expression of p21 and gelsolin. Group: Biochemicals. Alternative Names: Cyclo[(2S)-2-amino-8-oxodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl-(2R)-2-piperidinecarbonyl]; Cyclo(8-oxo-L-2-aminodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl-D-2-piperidinecarbonyl); Apicidin Ia; OSI 2040. Grades: Highly Purified. CAS No. 183506-66-3. Pack Sizes: 2mg. US Biological Life Sciences.
Cyclopeptide inhibitor of histone deactylases (HDACs). Inhibits HeLa cell proliferation (IC50=50-. Group: Biochemicals. Alternative Names: Cyclo- N-O-methyl-L-tryptophanyl-Lisoleucinyl- Dpipecolinyl- L-2-amino-8-oxodecanoyl. Grades: Highly Purified. CAS No. 183506-66-3. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
Worldwide
Apicularen A
Apicularen A is a macrolide antibiotic produced by Chondromyces robustus Cma 13. Apicularen A has no antibacterial activity, but for human and animal tumor cells such as KB-3-1, KB-V1, K-562, HL-60, U-937, A-498, A-549, PC-3 and SK-OV -3 grade has strong cytotoxicity. CAS No. 220757-04-0. Molecular formula: C25H31NO6. Mole weight: 441.52.
Apicularen B
Apicularen B is a macrolide antibiotic produced by Chondromyces robustus Cma 13. Apicularen B has low cytotoxicity and weak anti-Gram-positive bacteria activity. CAS No. 220757-06-2. Molecular formula: C33H44N2O11. Mole weight: 644.71.
Apidaecin IB acetate
Apidaecin IB acetate is an insect antimicrobial peptide with a minimum concentration of 8 μM against Escherichia coli (E. coli ML35, o18k1h7 and ATCC 25922). Synonyms: H-Gly-Asn-Asn-Arg-Pro-Val-Tyr-Ile-Pro-Gln-Pro-Arg-Pro-Pro-His-Pro-Arg-Leu-OH.CH3CO2H; glycyl-L-asparagyl-L-asparagyl-L-arginyl-L-prolyl-L-valyl-L-tyrosyl-L-isoleucyl-L-prolyl-L-glutaminyl-L-prolyl-L-arginyl-L-prolyl-L-prolyl-L-histidyl-L-prolyl-L-arginyl-L-leucine acetic acid; 18-L-leucine-Apidaecin Ia acetate; Apidaecin Ib acetate. Grades: ≥95%. Molecular formula: C97H154N32O25. Mole weight: 2168.46.
APIEZON GREASE M
Heterocyclic Organic Compound. Alternative Names: APIEZON GREASE M;APIEZON GREASE, TYPE M;APIEZON(R) M;GREASE APIEZON M;Grease of high temperature III;Apiezon M. CAS No. 12704-91-5. Catalog: ACM12704915.
Apiezon L
Heterocyclic Organic Compound. Alternative Names: APIEZON GREASE L;APIEZON GREASE, TYPE L;APIEZON(R) L;GREASE APIEZON L;ApiezonL;Grease of high temperature I;APIEZON(R) L, TUBE WITH 50 G;Apiezon Vacuum Grease L. CAS No. 12678-02-3. Catalog: ACM12678023.
Apigenin
Apigenin. Group: Biochemicals. Grades: Purified. CAS No. 520-36-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Apigenin
Apigenin. CAS No. 520-36-5. Product ID: PE-0323. Category: Active Pharmaceutical Ingredient. Product Keywords: Pharmaceutical Excipients; Other Materials; Active Pharmaceutical Ingredient; /; Apigenin; PE-0323; 520-36-5; 520-36-5. Grade: Pharmaceutical Grade.
Apigenin
Apigenin (4',5,7-Trihydroxyflavone) is a competitive CYP2C9 inhibitor with a K i of 2 μM. Uses: Scientific research. Group: Natural products. Alternative Names: 4',5,7-Trihydroxyflavone; Apigenol; C.I. Natural Yellow 1. CAS No. 520-36-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-N1201.
Apigenin
Apigenin is the main active ingredient of Chamomil Extract. Chamomile is rich in flavonoid active ingredients, which has antioxidant, anti-angiogenic, anti-inflammatory, anti-allergic and anti-viral effects. The active ingredients of chamomile can be applied to high-end anti-sensitive skin care products through issofree technology. It has a good soothing effect on itchy skin, it gently replenishes water and soothes the skin. Apigenin is a potent P450 inhibitor for CYP2C9 with Ki of 2 μM. Apigenin is a good functional cosmetics material. Synonyms: NSC 83244; NSC83244; NSC-83244; LY 080400; LY080400; LY-080400; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one; Chamomile; Spigenin; Versulin; Chamomil Extract. Grades: 5%-98%; 10:1. CAS No. 520-36-5. Molecular formula: C15H10O5. Mole weight: 270.24.
Apigenin
1g Pack Size. Group: Aroma Chemicals, Building Blocks, Organics. Formula: C15H10O5. CAS No. 520-36-5. Prepack ID 22930039-1g. Molecular Weight 270.24. See USA prepack pricing.
Apigenin
Apigenin - Product ID: NST-10-78. Category: Flavonoids. Alternative Names: Baicalein-7-O-glucuronide. Purity: 98%. Test method: HPLC. CAS No. 520-36-5. Pack Sizes: 10g, 20g, 50g, 100g. Appearance: Yellow Powder. Molecular formula: C15H10O5. Mole weight: 270.24. Storage: +2 +8 °C.
Apigenin (4',5,7-Trihydroxyflavone)
Induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignan. Group: Biochemicals. Alternative Names: 4',5,7-Trihydroxyflavone. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Apigenin 4'-β-D-Gucopyranoside Triacetate Methyl Ester is an intermediate in synthesizing Isorhoifolin, a naturally occurring flavonoid that was shown to exhibit potential antidiabetic, antihyperlipidemic and antioxidant effects. Synonyms: (2S,3R,4S,5S,6S)-2-(4-(5,7-Dihydroxy-4-oxochroman-2-yl)phenoxy)-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl Triacetate. Molecular formula: C28H28O14. Mole weight: 588.51.
Apigenin 4'-O- β-D-Glucuronide
Flavone component of the aerial parts of alfalfa (Medicago sativa L.) and pyrethrum flowers (Chrysanthemum cinerarifolium). Apigenin 4'-O- β-D-Glucuronide can be utilized for food or feed use and biological study of chemical composition of protein-xanthophyll concentrate dietary supplement made from alfalfa. Group: Biochemicals. Grades: Highly Purified. CAS No. 51771-57-4. Pack Sizes: 1mg, 5mg. Molecular Formula: C21H18O11, Molecular Weight: 446.36. US Biological Life Sciences.
Worldwide
apigenin 4'-O-methyltransferase
Converts apigenin into acacetin. Naringenin can also act as an acceptor, but more slowly. Group: Enzymes. Synonyms: flavonoid O-methyltransferase; flavonoid methyltransferase; S-adenosyl-L-methionine:5,7,4'-trihydroxyflavone 4'-O-methyltransferase. Enzyme Commission Number: EC 2.1.1.75. CAS No. 118251-36-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1976; apigenin 4'-O-methyltransferase; EC 2.1.1.75; 118251-36-8; flavonoid O-methyltransferase; flavonoid methyltransferase; S-adenosyl-L-methionine:5,7,4'-trihydroxyflavone 4'-O-methyltransferase. Cat No: EXWM-1976.
Apigenin-4'-O-sulfate Potassium Salt
Apigenin-4'-O-sulfate Potassium Salt is a sulfated form of Apigenin (A726500) flavone, present in numerous plant species. Group: Biochemicals. Grades: Highly Purified. CAS No. 120537-28-2. Pack Sizes: 1mg, 5mg. Molecular Formula: C15H9KO8S, Molecular Weight: 388.39. US Biological Life Sciences.
Worldwide
Apigenin 5-O-neohesperidoside
Apigenin 5-O-neohesperidoside is a natural flavonoid compound found in several plants. Synonyms: 5-[[2-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-7-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one. Grades: >95%. CAS No. 850630-40-9. Molecular formula: C27H30O14. Mole weight: 578.52.
A compound of the flavonoid class found in the Viola yedoensis. Synonyms: 6-C-alpha-L-Arabinopyranosyl-8-C-beta-D-xylopyranosylapigenin. Grades: >98%. CAS No. 677021-30-6. Molecular formula: C25H26O13. Mole weight: 534.47.
Apigenin 7- β-D-Gucopyranoside Triacetate Methyl Ester is an intermediate in synthesizing Isorhoifolin (I819700), a naturally occurring flavonoid that was shown to exhibit potential antidiabetic, antihyperlipidemic and antioxidant effects. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 100mg. Molecular Formula: C28H28O14, Molecular Weight: 588.51. US Biological Life Sciences.
Apigenin 7-β-D-Gucopyranoside Triacetate Methyl Ester is an intermediate in synthesizing Isorhoifolin, a naturally occurring flavonoid that was shown to exhibit potential antidiabetic, antihyperlipidemic and antioxidant effects. Synonyms: (2S,3R,4S,5S,6S)-2-((5-Hydroxy-2-(4-hydroxyphenyl)-4-oxochroman-7-yl)oxy)-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl Triacetate. Molecular formula: C28H28O14. Mole weight: 588.51.
Apigenin 7-glucoside
Apigenin-7-glucoside (Apigenin-7-O-β-D-glucopyranoside) exhibits significant anti-proliferative and antioxidant activity and scavenges reactive oxygen species (ROS) [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Apigenin-7-O-β-D-glucopyranoside; Cosmosiin; Apigetrin. CAS No. 578-74-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0578.
Apigenin 7-O- (2G-rhamnosyl) gentiobioside
Apigenin 7-O- (2G-rhamnosyl) gentiobioside. Group: Biochemicals. CAS No. 174284-20-9. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Apigenin 7-O-(2G-rhamnosyl)gentiobioside
Apigenin 7-O-(2G-rhamnosyl)gentiobioside, a flavonoid compound ubiquitously present in a multitude of plants, specifically in parsley, celery, and chamomile, has been established to hold an impressive armory of antioxidant, anti-inflammatory, and anti-cancer activities. Its therapeutic potential in treating several diseases, including cardiovascular diseases, neurodegenerative diseases, and diabetes, has been suggested by extensive research studies. Moreover, it has been observed to manifest antiviral properties against a diverse pool of viruses, such as HIV-1. Synonyms: Apigenin-7-O-(2G-rhamnosyl)gentiobioside. Grades: >98%. CAS No. 174284-20-9. Molecular formula: C33H40O19. Mole weight: 740.7.
Apigenin-7-O - (2G-rhamnosyl) gentiobioside
Apigenin-7-O - (2G-rhamnosyl) gentiobioside. Group: Biochemicals. Alternative Names: Apigenin 7- (2G-rhamnosyl) gentiobioside. Grades: Plant Grade. CAS No. 174284-20-9. Pack Sizes: 10mg. Molecular Formula: C33H40O19, Molecular Weight: 740.66. US Biological Life Sciences.
Worldwide
apigenin-7-O-glucronide
Apigenin-7-glucuronide inhibited the major pathways of arachidonate metabolism in leukocytes. Synonyms: 5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl beta-D-glucopyranosiduronic acid. Grades: >98%. CAS No. 29741-09-1. Molecular formula: C21H18O11. Mole weight: 446.4.
Apigenin 7-O-glucuronide
Apigenin 7-O-glucuronide. Group: Biochemicals. CAS No. 29741-09-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Apigenin-7-O-glucuronide
Apigenin-7-O-glucuronide. Group: Biochemicals. Grades: Plant Grade. CAS No. 29741-09-1. Pack Sizes: 10mg. Molecular Formula: C21H18O11, Molecular Weight: 446.36. US Biological Life Sciences.
Worldwide
Apigenin 7-O-malonylglucoside
Apigenin 7-O-malonylglucoside is a flavonoid isolated from Chamomilla recutita. Synonyms: Apigenin 7-O-malonylglucoside; AOF5Z3UWMW; Apigenin 7-O-(6''-O-malonylglucoside); Apigenin 7-O-(6-malonyl-beta-D-glucoside); C10020; Apigenin 7-(6''-malonylglucoside); Apigenin 7-O-(6-O-malonylglucoside); 3-oxo-3-[[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[5-hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxyoxan-2-yl]methoxy]propanoic acid; Apigenin 7-O-(6 inverted exclamation mark -O-malonyl)-|A-D-glucoside. Grades: 0.98. CAS No. 86546-87-4. Molecular formula: C24H22O13. Mole weight: 518.42.
Apigenin-d5 7-Glucuronide is labelled Apigenin 7-Glucuronide (A726505), a metabolite of Apigenin, which induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignant tumor cells by G2/M arrest and induces morphological differentiation. Apigenin has also been reported to enhance the gap junction intracellular communication in liver cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C21H13D5O11, Molecular Weight: 451.39. US Biological Life Sciences.
Worldwide
Apigenin-d5 (Major)
The labeled aglucon of apiin and of apigenin-7-glucoside. Group: Biochemicals. Alternative Names: 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one-d5; 4',5,7-Trihydroxyflavone-d5; Pelargidenon 1449-d5; [3,6,8,3,5-d5]-Apigenin. Grades: Highly Purified. CAS No. 263711-74-6. Pack Sizes: 1mg. US Biological Life Sciences.
Apigeninidin (Gesneridin) is a chemical compound belonging to the 3-deoxyanthocyanidins and that was found in the Patagonian plant Ephedra frustillata and in the soybean. Apigeninidin is one of the principal pigments found in sorghum. Apigeninidin has antibiotic and antifungal properties. Synonyms: 3-desoxy Pelargonidin. Grades: ≥98%. CAS No. 1151-98-0. Molecular formula: C15H11O4·Cl. Mole weight: 290.7.
Apigenin impurity 1
Apigenin impurity 1. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C21H18O11. Mole Weight: 446.36. Catalog: APB11504.
Apigenin Liposome
Apigenin (AP) is a natural flavonoid with a variety of biological activities such as antioxidant, anti-inflammatory, anti-cancer and autoimmunity. This product is a pre-formulated liposome encapsulating Apigenin. It is only for research purposes. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes.
Apigetrin (Apigenin-7-O-glucoside)
Apigetrin (Apigenin-7-O-glucoside). Group: Biochemicals. Alternative Names: Apigenin 7-O-glucoside; Cosmetin. Grades: Plant Grade. CAS No. 578-74-5. Pack Sizes: 20mg. Molecular Formula: C21H20O10, Molecular Weight: 432.38. US Biological Life Sciences.
Worldwide
AP-III-a4
AP-III-a4 is a novel small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 μM); inhibit cancer cell metastasis in vivo. Synonyms: ENOblock. Grades: >98%. CAS No. 1177827-73-4. Molecular formula: C31H43FN8O3. Mole weight: 594.72.
AP-III-a4
AP-III-a4 (ENOblock) is a nonsubstrate analogue enolase inhibitor with an IC 50 of 0.576 uM. AP-III-a4 can be used for the research of cancer and diabetic [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ENOblock. CAS No. 1177827-73-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15858.
AP-III-a4
AP-III-a4, also known as ENOblock, is the first, nonsubstrate inhibitor of enolase, blocking cancer cell metastasis in vivo. biochemical analysis showed that the half maximal inhibitory concentration (IC50) of enolase inhibition by ENOblock is 0.576 μM. ENOblock can inhibit cancer cell metastasis in vivo. Moreover, an unexpected role for enolase in glucose homeostasis was revealed by in vivo analysis. ENOblock is the first reported enolase inhibitor that is suitable for biological assays. Group: Inhibitors. Alternative Names: AP-III-a4; ENOblock. CAS No. 1177827-73-4. Molecular formula: C31H43FN8O3. Mole weight: 594.74. Appearance: Solid powder. Purity: >98%. IUPACName: N-[2-[2- (2-Aminoethoxy)ethoxy]ethyl]-4-[[4-[ (cyclohexylmethyl)amino]-6-[[ (4-fluorophenyl)methyl]amino]-1, 3, 5-triazin-2-yl]amino]benzeneacetamide. Canonical SMILES: O=C (NCCOCCOCCN)CC1=CC=C (NC2=NC (NCC3CCCCC3)=NC (NCC4=CC=C (F)C=C4)=N2)C=C1. Catalog: ACM1177827734.
AP-III-a4 hydrochloride
AP-III-a4 (ENOblock) hydrochloride is a nonsubstrate analogue enolase inhibitor with an IC 50 of 0.576 uM. AP-III-a4 hydrochloride can be used for the research of cancer and diabetic [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ENOblock hydrochloride. CAS No. 2070014-95-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15858A.
Apiin
Apiin, a major constituent of Apium graveolens leaves with anti-inflammatory properties. Apiin shows significant inhibitory activity on nitrite (NO) production (IC 50 = 0.08 mg/mL) in-vitro and iNOS expression (IC 50 = 0.049 mg/ mL) in LPS-activated J774.A1 cells [1]. Uses: Scientific research. Group: Natural products. CAS No. 26544-34-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0577.
Apiin
Apiin is a flavonoid compound extracted from parsley which shows inhibition towards viral neuramindase. It also shows antiproliferative and apoptotic effects towards human cancer cells. Uses: Antiproliferative/apoptotic. Synonyms: Apigenin-7-(2-O-apiosylglucoside) 7-[2-O-(Apio-b-D-furanosy)l-b-D-glucopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one. Grades: >98%. CAS No. 26544-34-3. Molecular formula: C26H28O14. Mole weight: 564.50.
Apiin
Apiin. Group: Biochemicals. Grades: Plant Grade. CAS No. 26544-34-3. Pack Sizes: 20mg. Molecular Formula: C26H28O14, Molecular Weight: 564.49. US Biological Life Sciences.
Worldwide
Apilimod
Apilimod is a potent and orally bioavailable inhibitor of the cytokines interleukin-12 (IL-12) and interleukin-23 (IL-23) with the potential to treat certain autoimmune and inflammatory diseases by inhibition of IL-12 and IL-23 production. Synonyms: STA-5326; STA 5326;STA5326; N-[(E)-(3-methylphenyl)methylideneamino]-6-morpholin-4-yl-2-(2-pyridin-2-ylethoxy)pyrimidin-4-amine. Grades: 99%. CAS No. 541550-19-0. Molecular formula: C23H26N6O2. Mole weight: 418.49.
Apilimod
Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC 50 s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively [1]. Apilimod is a potent and highly selective PIKfyve inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: STA 5326; LAM-002A free base; AIT-101. CAS No. 541550-19-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14644.
Apilimod mesylate
The mesylate salt form of Apilimod. Apilimod is a potent and orally-available inhibitor of the cytokines interleukin-12 (IL-12) and interleukin-23 (IL-23) with the potential to treat certain autoimmune and inflammatory diseases by inhibition of IL-12 and IL-23 production. Synonyms: methanesulfonic acid N-[(E)-(3-methylphenyl)methylideneamino]-6-morpholin-4-yl-2-(2-pyridin-2-ylethoxy)pyrimidin-4-amine. Grades: 98%. CAS No. 870087-36-8. Molecular formula: C23H26N6O2.2CH4O3S. Mole weight: 610.7.
Apilimod mesylate
Apilimod (STA 5326) mesylate is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC 50 s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively [1]. Apilimod is a potent and highly selective PIKfyve inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: STA 5326 mesylate; LAM-002A; AIT-101 mesylate. CAS No. 870087-36-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14644A.
Apimostinel
Apimostinel is a selective partial agonist of an allosteric site of the glycine site of the NMDA receptor complex under investigation by Naurex. Its mechanism of action and effects are similar to those of rapastinel. But Apimostinel is 100-fold more potent by weight and, unlike rapastinel (which must be administered via intravenous injection), is orally-active. Phase II clinical trials for the treatment of Major depressive disorder is on-going. Uses: Major depressive disorder. Synonyms: NRX-1074; NRX 1074; NRX1074; AGN-241660; AGN241660; AGN 241660. Apimostinel;(2R)-1-[(2S)-1-[(2S,3R)-2-amino-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]-N-[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]-2-benzylpyrrolidine-2-carboxamide. Grades: 98%. CAS No. 1421866-48-9. Molecular formula: C25H37N5O6. Mole weight: 503.60.
Apimostinel
Apimostinel (NRX-1074; AGN-241660) is an orally active NMDA receptor partial agonist [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NRX-1074; AGN-241660. CAS No. 1421866-48-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102053.
a-Pinene oxide
a-Pinene oxide. Group: Biochemicals. Grades: Highly Purified. CAS No. 1686-14-2. Pack Sizes: 25g, 50g, 100g, 250g, 500g. US Biological Life Sciences.
Worldwide
Apinocaltamide
Apinocaltamide (ACT-709478) is a potent, selective, orally active, and brain penetrating T-type calcium channel blocker. ACT-709478 is used in the research of generalized epilepsies [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACT-709478. CAS No. 1838651-58-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112723.
Apiogalacturonan
Apiogalacturonan, depicted as a remarkable bioactive polysaccharide deeply rooted in the plant kingdom, showcasing immense promise application in studying diverse ailments such as malignancies, diabetes and cardiovascular afflictions. Synonyms: Galacturonoapian. CAS No. 9039-3-6.
Apiopaeonoside. Group: Biochemicals. Grades: Plant Grade. CAS No. 100291-86-9. Pack Sizes: 20mg. Molecular Formula: C20H28O12, Molecular Weight: 460.43. US Biological Life Sciences.
Worldwide
Apiopaeonoside
Apiopaeonoside is a phenol isolated from the root of Paeonia suffruticosa. Synonyms: Apiopeonoside. Grades: 0.98. CAS No. 100291-86-9. Molecular formula: C20H28O12. Mole weight: 460.43.
apiose 1-reductase
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-apiitol:NAD+ 1-oxidoreductase. Other names in common use include D-apiose reductase, and D-apiitol reductase. Group: Enzymes. Synonyms: D-apiose reductase; D-apiitol reductase. Enzyme Commission Number: EC 1.1.1.114. CAS No. 37250-45-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0017; apiose 1-reductase; EC 1.1.1.114; 37250-45-6; D-apiose reductase; D-apiitol reductase. Cat No: EXWM-0017.
Apiosylskimmin
Apiosylskimmin is a natural product from plants. Synonyms: 2H-1-Benzopyran-2-one,7-[(6-O-D-apio-b-D-furanosyl-b-D-glucopyranosyl)oxy]-; MLS002473238; CHEMBL1719219; MolPort-006-668-333; 7-[(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl]oxychromen-2-one. CAS No. 103529-94-8. Molecular formula: C20H24O12. Mole weight: 456.41.
Apitegromab
Apitegromab (SRK-015) is an anti-promyostatin monoclonal antibody. Apitegromab can be used for the research of neuromuscular disease including spinal muscular atrophy [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SRK-015. CAS No. 2278276-46-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99441.
Apitolisib
Apitolisib, also known as GDC-0980 and RG7422; or GNE390, is a dual PI3 kinase/mTOR inhibitor, is also an orally available agent targeting phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (mTOR) kinase in the PI3K/mTOR signaling pathway, with potential antineoplastic activity. PI3K/mTOR kinase inhibitor GDC-0980 inhibits both PI3K kinase and mTOR kinase, which may result in tumor cell apoptosis and growth inhibition of cancer cells overexpressing PI3K/mTOR. Activation of the PI3K/mTOR pathway promotes cell growth, survival, and resistance to chemotherapy and radiotherapy; mTOR, a serine/threonine kinase downstream of PI3K, may also be activated in a PI3K-independent fashion. Synonyms: GDC-0980; GDC0980; GDC 0980; RG7422; RG-7422; RG 7422; GNE 390; GNE390; GNE-390; Apitolisib. CAS No. 1032754-93-0. Molecular formula: C23H30N8O3S. Mole weight: 498.606.
Apitolisib
Apitolisib (GDC-0980; GNE 390; RG 7422) is a selective, potent, orally bioavailable Class I PI3 kinase and mTOR kinase ( TORC1 / 2 ) inhibitor with IC 50 s of 5 nM/27 nM/7 nM/14 nM for PI3Kα /PI3Kβ /PI3Kδ /PI3Kγ , and with a K i of 17 nM for mTOR. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-0980; GNE 390; RG 7422. CAS No. 1032754-93-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13246.