A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Asperuloside. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ASPERULOSIDE;RUBICHLORIC ACID;[2aS-(2aalpha,4aalpha,5alpha,7balpha)]-5-(beta-D-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-1-oxo-1H-2,6-dioxacyclopent[cd]inden-4-ylmethyl acetate;1H-2,6-Dioxacyclopentcdinden-1-one, 4-(acetyloxy)methyl-5-(.beta.-D-glucopyran. Product Category: Heterocyclic Organic Compound. Appearance: White powder. CAS No. 14259-45-1. Molecular formula: C18H22O11. Mole weight: 414.4. Purity: 0.98. Canonical SMILES: CC(=O)OCC1=CC2C3C1C(OC=C3C(=O)O2)OC4C(C(C(C(O4)CO)O)O)O. Density: 5mg 10mg 20 mg. Product ID: ACM14259451. Alfa Chemistry ISO 9001:2015 Certified.
Asperuloside (Rubichloric acid)
Asperuloside (Rubichloric acid). Group: Biochemicals. Alternative Names: Rubichloric acid. Grades: Plant Grade. CAS No. 14259-45-1. Pack Sizes: 20mg. Molecular Formula: C18H22O11, Molecular Weight: 414.363. US Biological Life Sciences.
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Asperulosidic acid
Asperulosidic acid is a naturally occurring compound abundant in diverse plants, garnering immense interest due to its remarkable pharmacological activities. Its anti-inflammatory and antioxidant attributes have propelled its prominence in the biomedical research. Synonyms: (1S,4aS,5S,7aS)-7-[(acetyloxy)methyl]-1-(beta-D-glucopyranosyloxy)-5-hydroxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylic acid. Grades: >98%. CAS No. 25368-11-0. Molecular formula: C18H24O12. Mole weight: 432.4.
Asperulosidic Acid
Botanical Source: Group: Biochemicals. Grades: Plant Grade. CAS No. 25368-11-0. Pack Sizes: 10mg, 20mg. US Biological Life Sciences.
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Asphalt
Synonyms: Asphalt; Bitumen. Grades: 95%. CAS No. 8052-42-4.
Asphaltum (technical grade)
Asphaltum (technical grade). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Bitumen. Product Category: Promotional Products. CAS No. 8052-42-4. Purity: Tech. Product ID: ACM8052424-1. Alfa Chemistry ISO 9001:2015 Certified.
Aspicilin
It is obtained from the lichens Aspicilia calcarea and A. gibbosa. Synonyms: (-)-Aspicillin; (5R,6S,7R,18S,E)-5,6,7-trihydroxy-18-methyloxacyclooctadec-3-en-2-one; (3E,5R,6S,7R,18S)-5,6,7-Trihydroxy-18-methyloxacyclooctadeca-3-en-2-one; Oxacyclooctadec-3-en-2-one, 5,6,7-trihydroxy-18-methyl-, (3E,5R,6S,7R,18S)-. Grades: 99%. CAS No. 52461-05-9. Molecular formula: C18H32O5. Mole weight: 328.44.
Aspiculamycin
Aspiculamycin is a nucleoside peptide antibiotic produced by Streptomyces toyocaensis var. aspiculamyceticus. It has weak anti-Gram-positive bacteria, negative bacteria, mycobacteria and mycoplasma activity, and has the effect of repelling worms, nematodes and killing worms. Synonyms: Aspiculamycin; Quingfengmycin; Gougerotin. Molecular formula: C19H30O10N8. Mole weight: 530.49.
Aspinonene
Aspinonene. Uses: Designed for use in research and industrial production. Additional or Alternative Names: aspinonene, CTK8F0847, 157676-96-5. Product Category: Heterocyclic Organic Compound. CAS No. 157676-96-5. Molecular formula: C9H16O4. Mole weight: 188.220940 [g/mol]. Purity: 0.96. IUPACName: (2R,5S)-2-[(2R,3S)-3-methyloxiran-2-yl]hex-3-ene-1,2,5-triol. Product ID: ACM157676965. Alfa Chemistry ISO 9001:2015 Certified.
Multifunctional fungal secondary metabolite. Related to aspyrone. Group: Biochemicals. Grades: Highly Purified. CAS No. 157676-96-5. Pack Sizes: 1mg. US Biological Life Sciences.
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Aspirin
Aspirin (Acetylsalicylic Acid) is an orally active, potent and irreversible inhibitor of cyclooxygenase COX-1 and COX-2 , with IC 50 values of 5 and 210 μg/mL, respectively. Aspirin induces apoptosis. Aspirin inhibits the activation of NF-κB. Aspirin also inhibits platelet prostaglandin synthetase , and can prevent coronary artery and cerebrovascular thrombosis [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Acetylsalicylic Acid; ASA. CAS No. 50-78-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-14654.
Aspirin
Aspirin is a salicylate and irreversible COX1 and COX2 inhibitor. It can be used for the treatment of fever, rheumatism, nerve, muscle, joint pain, soft tissue inflammation and gout in animals. Synonyms: Acetylsalicylic acid; 1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12). Grades: 99.66%. CAS No. 50-78-2. Molecular formula: C9H8O4. Mole weight: 180.16.
Aspirin Aluminum
Aspirin Aluminum is a novel intermolecular compound which can inhibit gastrointestinal mucosal disorders induced by NSAIDs (non-steroidal anti-inflammatory agents) extracted from patent WO 2010064441 A1. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Aluminum diacetylsalicylate. CAS No. 23413-80-1. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B2175.
Aspirin Impurity 1
Aspirin Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C16H12O6. Mole Weight: 300.27. Catalog: APB06604.
Aspirin Impurity 11
Aspirin Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 85531-16-4. Molecular Formula: C23H16O8. Mole Weight: 420.37. Catalog: APB85531164.
Aspirin Impurity 16
Aspirin Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 24719-72-0. Molecular Formula: C15H16O10. Mole Weight: 356.28. Catalog: APB24719720.
Aspirin Impurity 17
Aspirin Impurity 17. Uses: For analytical and research use. Group: Impurity standards. CAS No. 97781-16-3. Molecular Formula: C9H4D4O4. Mole Weight: 184.18. Catalog: APB97781163.
Aspirin Impurity 18
Aspirin Impurity 18. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C17H27N3O6. Mole Weight: 369.42. Catalog: APB06605.
Aspirin Impurity 19
Aspirin Impurity 19. Uses: For analytical and research use. Group: Impurity standards. CAS No. 85531-25-5. Molecular Formula: C15H12O5. Mole Weight: 272.26. Catalog: APB85531255.
Aspirin Impurity 2
Aspirin Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 318515-20-7. Molecular Formula: C12H10N2O3. Mole Weight: 230.22. Catalog: APB318515207.
Aspirin Impurity 3
Aspirin Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 15540-79-1. Molecular Formula: C8H7NO5. Mole Weight: 197.15. Catalog: APB15540791.
Aspirin Impurity 36
Aspirin Impurity 36. Uses: For analytical and research use. Group: Impurity standards. CAS No. 7695-70-7. Molecular Formula: C13H14O9. Mole Weight: 314.25. Catalog: APB7695707.
Aspirin Impurity 4
Aspirin Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2513-33-9. Molecular Formula: C14H10O5. Mole Weight: 258.23. Catalog: APB2513339.
Aspirin Impurity A-D4 (Aspirin Impurity 12)
Aspirin Impurity A-D4 (Aspirin Impurity 12). Uses: For analytical and research use. Group: Impurity standards. CAS No. 152404-47-2. Molecular Formula: C7H2D4O3. Mole Weight: 142.15. Catalog: APB152404472.
Aspirin Impurity Standard
Aspirin Impurity Standard. Uses: For analytical and research use. Group: British pharmacopoeia; pharmacopoeial standards. Catalog: APS005836. Format: Neat.
Aspirin-L-argininie
Aspirin-L-argininie. Group: Biochemicals. Grades: Highly Purified. CAS No. 37466-21-0. Pack Sizes: 500mg, 1000mg. Molecular Formula: C15H22N4O6, Molecular Weight: 354.36. US Biological Life Sciences.
Worldwide
Aspirin (Standard)
Aspirin (Standard) is the analytical standard of Aspirin. This product is intended for research and analytical applications. Aspirin (Acetylsalicylic Acid) is an orally active, potent and irreversible inhibitor of cyclooxygenase COX-1 and COX-2 , with IC 50 values of 5 and 210 μg/mL, respectively. Aspirin induces apoptosis. Aspirin inhibits the activation of NF-κB. Aspirin also inhibits platelet prostaglandin synthetase , and can prevent coronary artery and cerebrovascular thrombosis [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Acetylsalicylic Acid(Standard); ASA (Standard). CAS No. 50-78-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-14654R.
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500U; 2500U. GCG↑C C↓GCG. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer O. Storage: -20°C. Form: Liquid. Source: Arthrobacter species LE3860. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA; 50% glycerol. Cat No: RE-1025EN.
Asp-Leu
Alpha-Asp-Leu is a dipeptide formed from aspartic acid and leucine. Synonyms: H-ASP-LEU-OH; L-ASPARTIC ACID-L-LEUCINE; Asp-Leu-OH; L-Asp-L-Leu-OH; N-L-α-Aspartyl-L-leucine. Grades: ≥97% by HPLC. CAS No. 3062-14-4. Molecular formula: C10H18N2O5. Mole weight: 246.26.
Aspochalasin D
Aspochalasin D is a potent inhibitor of mammalian tumor cell lines, first isolated from Aspergillus microcysticus. It has antibacterial activity against Gram-positive and Gram-negative bacteria at a concentration of 1 mg/ml. Aspochalasin D was found that it can strongly induce the formation of actin-containing rodlets in the cytoplasm of treated fibroblasts. Synonyms: 1H-Cycloundec(d)isoindole-1,15(2H)-dione, 3,3a,4,6a,9,10,11,12-octahydro-11,12-dihydroxy-4,5,8-trimethyl-3-(2-methylpropyl)-, (3S,3aR,4S,6aS,7E,11R,12S,13E,15aS)-. Grades: ≥95%. CAS No. 71968-02-0. Molecular formula: C24H35NO4. Mole weight: 401.54.
Aspochalasine A
Aspochalasine is an antibiotic produced by Aspergillus microcysticus and an unidentified fungus FA2277. Aspochalasine A has anti-bacterial and fungal activity. Molecular formula: C24H33NO4. Mole weight: 399.52.
Aspochalasine E
Aspochalasine is an antibiotic produced by Aspergillus microcysticus and an unidentified fungus FA2277. Molecular formula: C24H33NO3. Mole weight: 383.52.
Aspochalasin I
Cytotoxic. Melanogenesis inhibitor without cytotoxicity. Group: Biochemicals. Alternative Names: (3E, 5R, 6S, 9E, 10aS, 13S, 13aS, 14S, 16aR)-6, 7, 8, 10a, 13, 13a, 14, 15-Octahydro-5, 6-dihydroxy-9, 12, 13-trimethyl-14-(2-methylpropyl)-2H-oxacyclododecino[2, 3-d]isoindole-2, 16(5H)-dione. Grades: Highly Purified. CAS No. 670225-69-1. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C24H35NO5, Molecular Weight: ~417.5. US Biological Life Sciences.
Worldwide
Aspochalasin M
Aspochalasin M is a fungal metabolite originally isolated from S. elegans. It can inhibit the growth of HL-60 cells (IC50 = 20 μM). Synonyms: Aspochalasin M; 1173040-34-0; (1S,5S,9Z,11S,14S,15R,16S)-5-hydroxy-9,13,14-trimethyl-16-(2-methylpropyl)-17-azatricyclo[9.7.0.01,15]octadeca-9,12-diene-2,6,18-trione; (3S,3aR,4S,6aS,7E,12S,15aS)-3,3a,4,6a,9,10,13,14-octahydro-12-hydroxy-4,5,8-trimethyl-3-(2-methylpropyl)-1H-cycloundec[d]isoindole-1,11,15(2H,12H)-trione. Grades: >95%. CAS No. 1173040-34-0. Molecular formula: C24H35NO4. Mole weight: 401.54.
Aspochracin
Aspochracin is a cyclic tripeptide isolated from Aspergillus first. Aspochracin is toxic to caught worms (LD50 = 100 μg/g) and silkworms. Grades: >95% by HPLC. CAS No. 22029-09-0. Molecular formula: C23H36N4O4. Mole weight: 432.56.
Aspoxicillin
Aspoxicillin is classified under the β-lactam family of antibiotics. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Aspoxicillin; TA 058; TA058; TA-058. Product Category: Others. Appearance: Solid powder. CAS No. 63358-49-6. Molecular formula: C21H27N5O7S. Mole weight: 493.54. Purity: >98%. IUPACName: Glycinamide, N-methyl-D-asparaginyl-N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-D-2-(4-hydroxyphenyl)-, (2S-(2-alpha,5-alpha,6-beta))-. Canonical SMILES: O=C(N)[C@@H](C1=CC=C(O)C=C1)N(C([C@@H](CC(N)=O)NC)=O)[C@H]2[C@@]3([H])SC(C)(C)C(C(O)=O)N3C2=O. Product ID: ACM63358496. Alfa Chemistry ISO 9001:2015 Certified.
Aspoxicillin
Aspoxicillin is a broad-spectrum antimicrobial agent against 68 isolates of Actinobacillus pleuropneumoniae with an MIC 90 value of <= 0.05 μg/ml. Aspoxicillin has a long half-life in mouse serum of 55 minutes [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 63358-49-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135842.
Aspoxicillin
Aspoxicillin is a semi-synthetic penicillin prepared from 6-aminopenicillanic acid (6-APA) or Amoxicillin. It has a broad antibacterial spectrum and has an effect on Pseudomonas aeruginosa. Synonyms: Aspoxicilina; Aspoxicilline; Aspoxicillinum. Grades: >98%. CAS No. 63358-49-6. Molecular formula: C21H27N5O7S. Mole weight: 493.53.
Asp-Phe
A metabolite of Aspartame. Synonyms: L-Aspartyl-L-phenylalanine. Grades: >98%. CAS No. 13433-09-5. Molecular formula: C13H16N2O5. Mole weight: 280.28.
AspS9 I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. G↑GNCC CCNG↓G. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer W. Storage: -20°C. Form: Liquid. Source: Arthrobacter species S9. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1026EN.
ASPT
ASPT. Uses: Designed for use in research and industrial production. Additional or Alternative Names: trans-4-[4-(N-Ethyl-2-hydroxyethylamino)styryl]-1-methyl pyridiniumtetra phenyl borate. Product Category: Other Fluorophores. Appearance: Orange to red powder. CAS No. 159721-38-7. Molecular formula: C42H43BN2O. Mole weight: 602.61. Purity: 95%+. IUPACName: 2-[N-ethyl-4-[(E)-2-(1-methylpyridin-1-ium-4-yl)ethenyl]anilino]ethanol;tetraphenylboranuide. Canonical SMILES: [B-](C1=CC=CC=C1)(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4.CCN(CCO)C1=CC=C(C=C1)/C=C/C2=CC=[N+](C=C2)C. Product ID: ACM159721387-1. Alfa Chemistry ISO 9001:2015 Certified.
Aspterric acid
Antibiotic. Pollen growth and development inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 67309-95-9. Pack Sizes: 1mg. US Biological Life Sciences.
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aspulvinone dimethylallyltransferase
This enzyme will also use as acceptor aspulvinone G, a hydroxylated derivative of the complex phenolic pigment aspulvinone E. Group: Enzymes. Synonyms: dimethylallyl pyrophosphate:aspulvinone dimethylallyltransferase. Enzyme Commission Number: EC 2.5.1.35. CAS No. 67584-68-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2772; aspulvinone dimethylallyltransferase; EC 2.5.1.35; 67584-68-3; dimethylallyl pyrophosphate:aspulvinone dimethylallyltransferase. Cat No: EXWM-2772.
Aspulvinone O
Aspulvinone O is a fungal metabolite originally isolated from P. variotti and has antioxidant and anticancer activities. It inhibits aspartate transaminase 1 (GOT1, Kd=3.32 μM) and is cytotoxic to PANC-1, AsPC-1, and SW1990 pancreatic cancer cells (IC50s = 20.54-26.8 μM). Aspulvinone O (2.5 and 5 mg/kg) reduces tumor growth in an SW1990 mouse xenograft model because it reduces the oxygen consumption rate (OCR) and induces apoptosis in SW1990 cells. Synonyms: 914071-54-8; 3-[2,4-dihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]-4-hydroxy-5-[[4-hydroxy-3-(3-methyl-2-buten-1-yl)phenyl]methylene]-2(5H)-furanone(5Z)-3-[2,4-dihydroxy-5-(3-methylbut-2-enyl)phenyl]-4-hydroxy-5-[[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]methylidene]furan-2-one; Aspulvinone OMEGxm0_000073. Grades: >98%. CAS No. 914071-54-8. Molecular formula: C27H28O6. Mole weight: 448.51.
Antibiotic. Shows nematicidal, insecticidal, antibacterial and antifungal activity. Related to asperlactone and aspinonene. Group: Biochemicals. Grades: Highly Purified. CAS No. 17398-00-4. Pack Sizes: 1mg, 5mg. Molecular Formula: C9H12O4. US Biological Life Sciences.
Worldwide
ASS234
ASS234 is a potent monoamino oxidase (MAO) inhibitor with IC 50 s of 5.2 nM and 43 nM for MAO-A and MAO-B, respectively. ASS234 also inhibits AChE and BuChE with IC 50 s of 350 nM and 460 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1334106-34-1. Pack Sizes: 5 mg. Product ID: HY-121072.
Assay Buffer (10X)
Assay Buffer (10X). Group: Molecular Biology. Alternative Names: For Human Topoisomerase I, Cat#T8065A. US Biological Life Sciences.
Worldwide
assemblin
Involved in the breakdown of the scaffold protein during the late stages of assembly of the herpes-virus virion. Inhibited by diisopropyl fluorophosphate. Type example of peptidase family S21. Catalytic residues are His, Ser, His, a combination not known for any other peptidase, and the protein fold also is unique. Known from herpes viruses of several types, cytomegalovirus, Epstein-Barr virus and human herpesvirus 3. Group: Enzymes. Enzyme Commission Number: EC 3.4.21.97. CAS No. 139691-88-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4189; assemblin; EC 3.4.21.97; 139691-88-6. Cat No: EXWM-4189.
assimilatory sulfite reductase (ferredoxin)
An iron protein. The enzyme participates in sulfate assimilation. While it is usually found in cyanobacteria, plants and algae, it has also been reported in bacteria. Different from EC 1.8.99.5, dissimilatory sulfite reductase, which is involved in prokaryotic sulfur-based energy metabolism. cf. EC 1.8.1.2, assimilatory sulfite reductase (NADPH). Group: Enzymes. Synonyms: ferredoxin-sulfite reductase; SIR (gene name); sulfite reductase (ferredoxin). Enzyme Commission Number: EC 1.8.7.1. CAS No. 37256-50-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1680; assimilatory sulfite reductase (ferredoxin); EC 1.8.7.1; 37256-50-1; ferredoxin-sulfite reductase; SIR (gene name); sulfite reductase (ferredoxin). Cat No: EXWM-1680.
assimilatory sulfite reductase (NADPH)
Contains siroheme, [4Fe-4S] cluster, FAD and FMN. The enzyme, which catalyses the six-electron reduction of sulfite to sulfide, is involved in sulfate assimilation in bacteria and yeast. Different from EC 1.8.99.5, dissimilatory sulfite reductase, which is involved in prokaryotic sulfur-based energy metabolism. cf. EC 1.8.7.1, assimilatory sulfite reductase (ferredoxin). Group: Enzymes. Synonyms: sulfite reductase (NADPH); sulfite (reduced nicotinamide adenine dinucleotide phosphate) reductase; NADPH-sulfite reductase; NADPH-dependent sulfite reductase; H2S-NADP oxidoreductase; sulfite reductase (NADPH2); MET5 (gene name); MET10 (gene name); cysI (gene name); cysJ (gene name). Enzyme Commission Number: EC 1.8.1.2. CAS No. 9029-35-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1646; assimilatory sulfite reductase (NADPH); EC 1.8.1.2; 9029-35-0; sulfite reductase (NADPH); sulfite (reduced nicotinamide adenine dinucleotide phosphate) reductase; NADPH-sulfite reductase; NADPH-dependent sulfite reductase; H2S-NADP oxidoreductase; sulfite reductase (NADPH2); MET5 (gene name); MET10 (gene name); cysI (gene name); cysJ (gene name). Cat No: EXWM-1646.
AST-1306
AST-1306 functions as an irreversible inhibitor, most likely through covalent interaction with Cys797 and Cys805 in the catalytic domains of EGFR and ErbB2, respectively. It inactivated pathways downstream of these receptors and thereby inhibited the proliferation of a panel of cancer cell lines. It blocks phosphorylation of EGFR and also prevents downstream pathways. It also dose-dependently inhibits EGF-induced EGFR phosphorylation in the A549 cancer cell line. Synonyms: AST-1306; AST 1306; AST1306. Grades: >98%. CAS No. 897383-62-9. Molecular formula: C24H18ClFN4O2. Mole weight: 448.88.
AST-1306
AST-1306 is a selective irreversible inhibitor of the epidermal growth factor receptor (EGFR) 1 and 2. Studies show that AST-1306 inhibited the enzymatic activities of wild-type EGF) and ErbB2 as well as EGFR resistant mutant in both cell-free and cell-based systems. AST-1306 was more effective in inhibiting tumors with ErbB2-overexpressing cells than EGFR-overexpressing tumor. Group: Biochemicals. Alternative Names: N- [4- [ [3-Chloro-4- [ (3-fluorobenzyl) oxy] phenyl] amino] quinazolin-6-yl] acrylamide; N-[4-[[3-Chloro-4-[ (3-fluorophenyl) methoxy]phenyl]amino]-6-quinazolinyl]-2-propenamide; ALS1306; AST 1306; AST 6. Grades: Highly Purified. CAS No. 897383-62-9. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
AST-1306 tosylate
AST-1306 is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, also effective in mutation EGFR T790M/L858R, more potent to ErbB2-overexpressing cells, 3000-fold selective for ErbB family than other kinases. Synonyms: AST-6; AST 6; AST6. Grades: >98%. CAS No. 1050500-29-2. Molecular formula: C24H18ClFN4O2,C7H8O3S. Mole weight: 621.08.
AST 487
AST487 is a Ret kinase inhibitor/FLT3 inhibitor, which displays high selectivity and potency toward FLT3 as a molecular target, and which could potentially be used to override drug resistance in AML. It induced a dose-dependent growth inhibition of xenografts of NIH3T3 cells expressing oncogenic RET, and of the MTC cell line TT in nude mice.It also inhibited calcitonin gene expression in vitro in TT cells, in part, through decreased gene transcription. Synonyms: NVP-AST 487; NVPAST487; AST 487; AST487; AST-487. Grades: >98%. CAS No. 630124-46-8. Molecular formula: C26H30F3N7O2. Mole weight: 529.56.
Potent RET kinase inhibitor. AST 487 displays high selectivity and potency toward FLT3 as a molecular target, and which could potentially be used to override drug resistance in AML. Group: Biochemicals. Grades: Highly Purified. CAS No. 630124-46-8. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
Worldwide
AST5902
AST5902 is the active metabolite of Firmonertinib (HY-112870) (EGFR inhibitor). AST5902 has antineoplastic activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2412155-74-7. Pack Sizes: 1 mg. Product ID: HY-138627.
AST5902
AST5902, a major metabolite of Alflutinib in vivo and in vitro, is an EGFR inhibitor with antineoplastic activity. Synonyms: 2-Propenamide, N-[5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[methyl[2-(methylamino)ethyl]amino]-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-; N-[5-[[4-(1-Methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[methyl[2-(methylamino)ethyl]amino]-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-2-propenamide; AST 5902; AST-5902. Grades: ≥95%. CAS No. 2412155-74-7. Molecular formula: C27H29F3N8O2. Mole weight: 554.57.
AST5902 mesylate
AST5902 mesylate, a major metabolite of Alflutinib in vivo and in vitro, is an EGFR inhibitor with antineoplastic activity. Synonyms: 2-Propenamide, N-[5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[methyl[2-(methylamino)ethyl]amino]-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-, compd. with methanesulfonate (1:1); AST 5902 mesylate; AST-5902 mesylate; N-(2-(methyl(2-(methylamino)ethyl)amino)-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)acrylamide methanesulfonate. Grades: ≥95%. CAS No. 2412155-75-8. Molecular formula: C27H29F3N8O2.CH4O3S. Mole weight: 650.67.
Astacene
Astacene. Group: Biochemicals. Alternative Names: 3,3'-Dihydroxy-2,3,2',3'-tetradehydro-b,b-carotene-4,4'-dione. Grades: Highly Purified. CAS No. 514-76-1. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences.
Worldwide
Astacidin
Astacidin is an antimicrobial peptide produced by Procambarus clarkii (freshwater crayfish Pacifastacus leniusculus). It encodes a peptide of 43 amino acids, with a signal peptide of 23 amino acids. The mature peptide contains 20 amino acids, among which four are proline/arginine amino acids. The synthetic mature peptide has inhibitory effects on both Gram-positive and gram-negative bacteria and has the ability to bind bacterial cell wall components, including peptidoglycan, lipopolysaccharide and lipophoteicic acid. Synonyms: PcAst; Met-Arg-Leu-Leu-His-Leu-Leu-Leu-Ser-Val-Ala-Leu-Val-Ala-Leu-Met-Ala-Ala-Val-Pro-Ser-Gln-Ala-Ser-Asn-Gly-Tyr-Arg-Pro-Ala-Tyr-Arg-Pro-Ala-Tyr-Arg-Pro-Ser-Tyr-Arg-Pro-Gly-Lys. Grades: >98%.
Astacidin 1
Astacidin 1 is an antimicrobial peptide produced by Pacifastacus leniusculus (Procambarus clarkii, Red swamp freshwater crayfish). It exhibits antifungal activity against Candida albicans, Trichosporon beigelii, Malassezia furfur and Trichophyton rubrum. Synonyms: H-Phe-Lys-Val-Gln-Asn-Gln-His-Gly-Gln-Val-Val-Lys-Ile-Phe-His-His-OH; L-phenylalanyl-L-lysyl-L-valyl-L-glutaminyl-L-asparaginyl-L-glutaminyl-L-histidylglycyl-L-glutaminyl-L-valyl-L-valyl-L-lysyl-L-isoleucyl-L-phenylalanyl-L-histidyl-L-histidine. Grades: >97%. Molecular formula: C90H136N28O21. Mole weight: 1946.24.
Astacidin 2
Astacidin 2 is an antimicrobial peptide produced by Pacifastacus leniusculus (freshwater signal crayfish). It has a broad range of antibacterial activity against gram-positive and gram-negative bacteria. Synonyms: Arg-Pro-Arg-Pro-Asn-Tyr-Arg-Pro-Arg-Pro-Ile-Tyr-Arg-Pro-NH2. Grades: ≥95%. Molecular formula: C83H133N31O17. Mole weight: 1837.18.
astacin
A 22.6 kDa digestive endopeptidase from the cardia of the crayfish Astacus fluviatilis. Type example of peptidase family M12. Group: Enzymes. Synonyms: Astacus proteinase; crayfish small-molecule proteinase. Enzyme Commission Number: EC 3.4.24.21. CAS No. 143179-21-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4302; astacin; EC 3.4.24.21; 143179-21-9; Astacus proteinase; crayfish small-molecule proteinase. Cat No: EXWM-4302.
Astaxanthin
Astaxanthin. Synonyms: 3,3'-DIHYDROXY-B,B-CAROTENE-4,4'-DIONE;3,3-DIHYDROXY-B,B-CAROTENE-4,4-DIONE;3,3'-DIHYDROXY-BETA,BETA-CAROTENE-4,4'-DIONE;ASTAXANTHIN;AXN;Astazine 5%;(3S,3S)-3,3-Dihydroxy-.beta.. beta.-carotene-4,4-dione;HAEMATOCOCCUS PLUVIALIS. CAS No. 472-61-7. Pack Sizes: 1 kg. Product ID: CDF4-0145. Molecular formula: C40H52O4. Category: Nutrients. Product Keywords: Food Ingredients; Nutrients; Astaxanthin; CDF4-0145; 472-61-7; C40H52O4; 207-451-4; 472-61-7. Purity: 0.99. Color: pink to very dark purple. EC Number: 207-451-4. Physical State: Powder. Solubility: DMSO: soluble1mg/mL (warmed). Storage: -20°C. Boiling Point: 568.55°C (rough estimate). Melting Point: 215-216 °C. Density: 0.9980 (rough estimate). Product Description: all-trans-Astaxanthin is a ketocarotenoid, most commonly identified in marine and aquatic animals, including krill, wild salmon, rainbow trout, microalgae, shells of lobster, shrimp, seafood products, etc. It is biologically known as a vitamin A precursor, and exhibits strong antioxidant property, much higher compared to vitamin E and β-carotene. Its role in food and the medicinal industry is also well-defined.
Astaxanthin
Astaxanthin, the red dietary carotenoid, is an orally effective and potent antioxidant. Astaxanthin inhibits NF-κB and down-regulates VEGF in blood glucose. Astaxanthin exerts anti-cancer cell proliferation, increases apoptosis , impairs migration and invasion by activating PPARγ and reducing the expression of STAT3. Astaxanthin also has neuroprotective and anti-inflammatory activity and can be used in studies of cancer, diabetic retinopathy, cardiovascular disease, and in the coloring of animal feed [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 472-61-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B2163.
Astaxanthin
Astaxanthin. Group: Others. Purity: 1%, 2%, 3%, 5%, 10% astaxanthin. Appearance: Dark red oil or powder. Astaxanthin. Cat No: EXTC-129.
Astaxanthin
Astaxanthin is a carotenoid pigment found mostly in animal organisms, but also occurring in plants. It is thought to be the precursor of astacin. It is a potent lipid-soluble antioxidant. It has broad application prospects in health products, medicine, cosmetics, food additives and aquaculture. Uses: Ingredient of health care products. Synonyms: Ovoester; Astaxanthine; (3S,3'S)-Astaxanthin; All-trans-Astaxanthin; 3,3'-Dihydroxy-β,β-carotene-4,4'-dione; 3,3'-Dhydroxy-4,4'-diketo-β-carotene; trans-Astaxanthin; (3S,3'S)-all-trans-Astaxanthin; (6S,6'S)-3,3'-((1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaene-1,18-diyl)bis(6-hydroxy-2,4,4-trimethylcyclohex-2-enone). Grades: ≥97%. CAS No. 472-61-7. Molecular formula: C40H52O4. Mole weight: 596.84.
Astaxanthin
1g Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials, Stains & Indicators. Formula: C40H52O4. CAS No. 472-61-7. Prepack ID 38028884-1g. Molecular Weight 596.84. See USA prepack pricing.