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| Product | Description | |
|---|---|---|
| AT-121 | AT-121 is a bifunctional nociception and mu opioid receptor agonist, with K i s of 3.67 and 16.49 nM, respectively. AT-121 is a safe, non-addictive analgesic, and shows antinociceptive and antiallodynic effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2099681-31-7. Pack Sizes: 100 μg (2.16 mM * 100 μL in Chloroform). Product ID: HY-112692. |  |
| AT-121 | T-121 is a dual μ-opioid and nociceptin receptor partial agonist (Kis = 16.49 and 3.67 nM, respectively). AT-121 can decrease capsaicin-induced thermal allodynia without increasing scratching activity in rhesus monkeys in a dose-dependent manner. Synonyms: AT-121; 2099681-31-7; N-[2-[1,2-dihydro-1'-[cis-4-(1-methylethyl)cyclohexyl]-3-oxospiro[isoquinoline-4(3H),4'-piperidin]-2-yl]ethyl]-sulfamide; 3-oxo-1'-(4-propan-2-ylcyclohexyl)-2-[2-(sulfamoylamino)ethyl]spiro[1H-isoquinoline-4,4'-piperidine]; SCHEMBL18920959; SCHEMBL20230173; SCHEMBL21179793; DTXSID801336428; GLXC-25688; EX-A8003; AKOS040755934; HY-112692; CS-0062666; Q56448036; N-{2-[1'-(cis-4-Isopropylcyclohexyl)-3-oxo-1H-spiro[isoquinoline-4,4'-piperidin]-2(3H)-yl]ethyl}sulfuric diamide. Grades: ≥95%. CAS No. 2099681-31-7. Molecular formula: C24H38N4O3S. Mole weight: 462.65. |  |
| AT-130 | AT-130, a phenylpropenamide derivative, is a potent hepatitis B virus (HBV) replication non-nucleoside inhibitor. AT-130 inhibits the viral DNA synthesis with an EC 50 of 0.13 μM. AT-130 inhibits both wt and mutant HBVs. AT-130 has anti-HBV activity in hepatoma cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 211364-06-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100028. | |
| AT13148 | AT13148 is an orally available multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity. It can block phosphorylation of AKT, p70S6K, PKA, ROCK and SGK substrates, and induce apoptosis in cancer cells. Synonyms: AT-13148; (1S)-2-amino-1-(4-chlorophenyl)-1-[4-(1H-pyrazol-4-yl)phenyl]ethanol. Grades: >98%. CAS No. 1056901-62-2. Molecular formula: C17H16ClN3O. Mole weight: 313.78. | |
| AT13148 | AT13148 is an orally active and ATP-competitive, multi- AGC kinase inhibitor with IC 50 s of 38 nM/402 nM/50 nM, 8 nM, 3 nM, and 6 nM/4 nM for Akt1/2/3, p70S6K, PKA, and ROCKI/II, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1056901-62-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16071. | |
| AT-1459 | AT-1459 is a novel, direct thrombin inhibitor with antithrombotic efficacy (Ki = 4.9 nM). Uses: Thrombin inhibitor. Synonyms: AT-1459; AT 1459; AT1459; UNII-JWP323ABVS; Butanoic acid, 4-[[(3S)?-1-[2-[(2S)?-2-[2-[6-(aminoiminomethyl)?-1-ethyl-1H-indol-2-yl]?ethyl]?-1-pyrrolidinyl]?-2-oxoethyl]?hexahydro-2-oxo-1H-azepin-3-yl]?amino]?-. Grades: ≥95%. CAS No. 294658-50-7. Molecular formula: C29H42N6O4. Mole weight: 538.32. | |
| AT 1902 | AT 1902 is a bio-active compound, but no detailed information has been published yet. Synonyms: AT 1902; AT-1902; AT1902; BRN 1714871; Nitriloacetic acid trihydride; NSC 351359; Nitrazine;Nitrazine;N,N-Bis(2-hydrazino-2-oxoethyl)glycine hydrazide;Glycine, N,N-bis(2-hydrazino-2-oxoethyl)-, hydrazide (9CI). Grades: 98%. CAS No. 80155-82-4. Molecular formula: C6H15N7O3. Mole weight: 233.23. | |
| AT 2433 A1 | AT 2433 A1 is an anti-tumor antibiotic produced by Actinomadura melliaura. It has activity against gram-positive bacteria. It can prolong the survival period of transplanted leukemia P388 mice. Synonyms: AT2433-A1; 6-Methyl-11-chloro-12-[6-O-[4-(methylamino)-2,4-dideoxy-alpha-L-threo-pentopyranosyl]-4-O-methyl-beta-D-glucopyranosyl]-12,13-dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione. Grades: >98%. CAS No. 102644-20-2. Molecular formula: C34H35ClN4O9. Mole weight: 679.11. | |
| AT 2433 A2 | AT 2433 A2 is an anti-tumor antibiotic produced by Actinomadura melliaura. It has activity against gram-positive bacteria. Synonyms: AT 2433-A2; AT2433-A2. Grades: >98%. CAS No. 102644-19-9. Molecular formula: C33H33ClN4O9. Mole weight: 665.09. | |
| AT 2433 B1 | AT 2433 B1 is an anti-tumor antibiotic produced by Actinomadura melliaura. It has activity against gram-positive bacteria. It can prolong the survival period of transplanted leukemia P388 mice. Synonyms: AT2433-B1. Grades: >98%. CAS No. 102622-96-8. Molecular formula: C34H36N4O9. Mole weight: 644.67. | |
| AT 2433 B2 | AT 2433 B2 is an anti-tumor antibiotic produced by Actinomadura melliaura. It has activity against gram-positive bacteria. Synonyms: AT2433-B2; 5H-Indolo(2,3-a)pyrrolo(3,4-c)carbazole-5,7(6H)-dione, 12-(6-O-(4-amino-2,4-dideoxypentopyranosyl)-4-O-methylhexopyranosyl)-12,13-dihydor-6-methyl-. Grades: >98%. CAS No. 102622-95-7. Molecular formula: C33H34N4O9. Mole weight: 630.64. | |
| AT-265 | AT-265 is a nucleoside antibiotic produced by Streptomyces rishiensis. It has anti-gram-positive and negative bacteria activity. Synonyms: 5'-Sulfamoyl-2-chloroadenosine; 2-chloro-5'-o-sulfamoyladenosine; Antibiotic AT 265. Grades: >98%. CAS No. 66522-52-9. Molecular formula: C10H13ClN6O6S. Mole weight: 380.77. | |
| AT-308 | AT-308 is a synthetic bio-active chemical. Uses: A synthetic bio-active chemical. Synonyms: AT-308; AT 308; AT308; AC1L4RQW; AC1Q642X; Ethyl 2-methyl-2-{4-[5-(pyridin-3-yl)-1,2,4-oxadiazol-3-yl]phenoxy}propanoate. Grades: ≥98%. CAS No. 40915-84-2. Molecular formula: C19H19N3O4. Mole weight: 353.38. | |
| AT-406 | AT-406 is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3 (with Ki of 66.4 nM), cIAP1-BIR3(with Ki of 1.9 nM) and cIAP2-BIR3 (with Ki of 5.1 nM), respectively. Synonyms: AT406; AT 406; SM-406; SM 406; SM406; ARRY-334543; ARRY 334543; ARRY334543. Grades: >98%. CAS No. 1071992-99-8. Molecular formula: C32H43N5O4. Mole weight: 561.71. | |
| AT 4930 | AT-4930 is a bio-active molecular, but detailed information has not been published yet. Synonyms: AT 4930; AT4930; AT-4930; 5-amino-1-cyclopropyl-7-(3,5-dimethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-Quinolinecarboxylic acid. Grades: 98%. CAS No. 123016-40-0. Molecular formula: C19H23FN4O. Mole weight: 374.41. | |
| AT 56 | AT 56. Group: Biochemicals. Grades: Purified. CAS No. 162640-98-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| AT-56 | Orally active inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS) (Ki = 75 muM, IC50 = 95 muM). Inhibits the production of PGD2 from PGH2 in vitro, with no effect on PGE2 or PGF2alpha production. Synonyms: AT 56; AT56; 4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-piperidine. Grades: ≥98%. CAS No. 162640-98-4. Molecular formula: C25H27N5. Mole weight: 397.53. | |
| AT-56 | AT-56. Group: Biochemicals. Alternative Names: 4-(5H-Dibenzo[a, d]cyclohepten-5-ylidene)-1-[4-(1H-tetrazol-5-yl)butyl]-piperidine. Grades: Highly Purified. CAS No. 162640-98-4. Pack Sizes: 5mg. Molecular Formula: C25H27N5, Molecular Weight: 397.52. US Biological Life Sciences. | Worldwide |
| AT-584 | AT-584, an azoniatricyclo compound, could have potential biological activity in pharmaceutical studies. Synonyms: AT 584; AT-584; AT584; Hexamethylenetetramine salt of p-(bis(2-chloroethyl)amino)-alpha-bromoacetophenone; 1-(p-(Bis(2-chloroethyl)amino)phenacyl)-3,5,7-triaza-1-azoniaadamantane bromide; 1-(2-(4-(Bis(2-chloroethyl)amino)phenyl)-2-oxoethyl)-3,5,7-triaza-1-azonia. Grades: 98%. CAS No. 16810-17-6. Molecular formula: C18H26BrCl2N5O. Mole weight: 479.24. | |
| AT6 | AT6 is an analogue of highly selective Brd4 degrader AT1, bearing thioether linkages of varying lengths. It led a dose-dependent degradation of BRD4 at concentration ranging in 30nM-3μM in HeLa cells. It works as a PROTAC selectively targeting on Brd4. Synonyms: AT 6; AT-6; (2S,4R)-1-((R)-14-acetamido-1-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-13,13-dimethyl-2-oxo-6,9-dioxa-12-thia-3-azapentadecan-15-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide. CAS No. 2098836-50-9. Molecular formula: C48H58ClN9O7S3. Mole weight: 1004.68. | |
| AT6 | AT6 is a PROTAC AT1 analogue, which is a PROTAC connected by ligands for von Hippel-Lindau and BRD4 with highly selectivity to bromodomain (Brd4). Uses: Scientific research. Group: Signaling pathways. CAS No. 2098836-50-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-112375. | |
| AT-61 | AT-61 is a nonnucleoside analogue inhibitors of hepatitis B virus (HBV) replication. Uses: Inhibitors of hepatitis b virus (hbv) replication. Synonyms: AT 61; AT-61; AT61; N-(1-(Bromophenylmethylene)-2-oxo-2-piperidylethyl)benzamide; Benzamide, N-(2-chloro-2-phenyl-1-(1-piperidinylcarbonyl)ethenyl)-; N-[1-(Bromophenylmethylene)-2-oxo-2-piperidylethyl]benzamide. Grades: ≥98%. CAS No. 300669-68-5. Molecular formula: C21H21ClN2O2. Mole weight: 368.86. | |
| AT7519 | AT7519 (AT7519M) as a potent inhibitor of CDKs , with IC 50 s of 210, 47, 100, 13, 170, and <10 nM for CDK1, CDK2, CDK4 to CDK6, and CDK9, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AT7519M. CAS No. 844442-38-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50940. | |
| AT-7519 | AT-7519 is an orally bioavailable small molecule CDK inhibitor with potential antineoplastic activity. AT7519M selectively binds to and inhibits cyclin dependent kinases (CDKs), which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation. Synonyms: AT-7519, AT7519, AT 7519, AT-7519 free base. Grades: 0.98. CAS No. 844442-38-2. Molecular formula: C16H17Cl2N5O2. Mole weight: 382.24. | |
| AT7519 HCl | AT-7519 is an orally bioavailable small molecule CDK inhibitor with potential antineoplastic activity. AT7519M selectively binds to and inhibits cyclin dependent kinases (CDKs), which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation. Synonyms: AT7519 HCl; AT 7519 HCl; AT-7519 HCl. CAS No. 902135-91-5. Molecular formula: C16H18Cl3N5O2. Mole weight: 418.71. | |
| AT7519 Hydrochloride | AT7519 Hydrochloride is a potent inhibitor of CDKs , with IC 50 s of 210, 47, 100, 13, 170, and <10 nM for CDK1, CDK2, CDK4 to CDK6, and CDK9, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 902135-91-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50943. | |
| AT 7519 mesylate | AT 7519 mesylate is a small-molecule inhibitor of CDK including CDK 1, 2, 4, 5, 6, and 9 in vitro and it induces apoptosis in multiple myeloma via GSK-3β activation and RNA polymerase II inhibition. Synonyms: AT 7519 mesylate; AT7519 mesylate; AT-7519 mesylate; AT-7519M; AT 7519M, AT7519M; 4-[(2,6-dichlorobenzoyl)amino]-N-piperidin-4-yl-1H-pyrazole-5-carboxamide methanesulfonic acid. Grades: 99%. CAS No. 902135-89-1. Molecular formula: C16H17Cl2N5O2.CH4O3S. Mole weight: 478.35. | |
| AT7519 TFA | AT7519 (AT7519M) TFA as a potent inhibitor of CDKs , with IC 50 s of 210, 47, 100, 13, 170, and <10 nM for CDK1, CDK2, CDK4 to CDK6, and CDK9, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AT7519M TFA. CAS No. 1431697-85-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50940A. | |
| AT7867 | AT7867 is a potent ATP-competitive inhibitor of Akt1 / Akt2 / Akt3 and p70S6K / PKA with IC 50 s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 857531-00-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-12059. | |
| AT7867 | AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively; little activity outside the AGC kinase family. Synonyms: AMG-706; AMG 706; AMG706; AT7867; AT 7867; AT-7867. Grades: >98%. CAS No. 857531-00-1. Molecular formula: C20H20ClN3. Mole weight: 337.85. | |
| AT7867 dihydrochloride | AT7867 also inhibits structurally related AGC kinases p70S6K and PKA with IC50 of 20 nM and 85 nM, respectively. AT7867 shows ATP-competitive activity to Akt2 with Ki of 18 nM. AT7867 exhibits antiproliferation in cell lines with PTEN or PIK3CA mutations and shows great potent to MES-SA, MDA-MB-468, MCF-7, HCT116 and HT29 with IC50 of 0.94 μM, 2.26 μM, 1.86 μM, 1.76 μM and 3.04 μM, respectively. AT7867 also suppresses the cell growth of U87MG, PC-3 and DU145 cells with IC50 of 8.22 μM, 10.37 μM and 11.86 μM, respectively. AT7867 suppresses Akt activity by inhibiting phosphorylation of GSK-3β in human tumor cells with IC50 of 2-4 μM. AT7867 also induces the phosphorylation of the following Akt direct substrates including proapoptotic transcription factors FKHR (FoxO1a), FKHRL1 (FoxO3a) and the downstream target S6RP in U87MG cells. AT7867 shows bioavailability of 44% in mice by p.o. route. AT7867 could increase the cleaved PARP in MES-SA xenografts at 20 mg/kg i.p. or 90 mg/kg p.o. AT7867 significantly inhibits the tumor growth in MES-SA xenografts or U87MG xenografts with T/C of 0.37 and 0.51, respectively. Synonyms: AT-7867 dihydrochloride; AT 7867 dihydrochloride. Grades: >98%. CAS No. 1431697-86-7. Molecular formula: C20H22Cl3N3. Mole weight: 410.77. | |
| AT7867 dihydrochloride | AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1 / Akt2 / Akt3 and p70S6K / PKA with IC 50 s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1431697-86-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12059A. | |
| At9283 | AT9283 is a multi-targeted kinase inhibitor with potent activity against Aurora A/B, JAK2/3, Abl (T315I) and Flt3 (IC50s ranging from 1 to 30 nM). AT9283 inhibits growth and survival of multiple solid tumors in vitro and in vivo. Group: Inhibitors. Alternative Names: 1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea;1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)ureaAT9283;AT9283, >=98%;N-cyclopropyl-N-[3-[5-(4-morpholinylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]Urea;Urea, N-cyclopropyl-N-[3-[6-(4-morpholinylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]-. CAS No. 896466-04-9. Molecular formula: C19H23N7O2. Mole weight: 381.438. Purity: 0.997. Density: 1.45. Catalog: ACM896466049. |  |
| AT9283 | AT-9283 is a broad spectrum kinase inhibitor that potently inhibits Aurora A, Aurora B, JAK2, JAK3, and c-ABL (IC50= 3, 3, 1.2, 1.1, and 4 nM, respectively). It also potently (IC50 = <1 μM) inhibits serine/threonine kinases as well as receptor and non-receptor tyrosine kinases. Synonyms: AT9283; AT 9283; AT-9283. Grades:>98%. CAS No. 896466-04-9. Molecular formula: C19H23N7O2. Mole weight: 381.43. | |
| AT9283 | AT9283 is a multi-targeted kinase inhibitor with potent activity against Aurora A/B , JAK2/3 , Abl (T315I) and Flt3 ( IC 50 s ranging from 1 to 30 nM). AT9283 inhibits growth and survival of multiple solid tumors in vitro and in vivo [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 896466-04-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50514. | |
| AT-9283 L-lactate | AT9283 is a multikinase inhibitor, is also a small-molecule inhibitor of several kinases with potential antineoplastic activity. AT9283 binds to and inhibits Aurora kinases A and B, JAK2 (Janus kinase 2) and the kinase BCR-ABL, which may result in the inhibition of cellular division and proliferation and the induction of apoptosis in tumor cells that overexpress these kinases. Synonyms: AT 9283; AT9283. CAS No. 896466-76-5. Molecular formula: C19H23N7O2. Mole weight: 471.52. | |
| Atabecestat | Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction. Atabecestat s tolerated and displays a sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat has the potential for Alzheimer's Disease treatment [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-54861911. CAS No. 1200493-78-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-109052. | |
| Atacicept | Atacicept (TACI-Ig) is a is a recombinant fusion protein containing the extracellular, ligand-binding portion of the TACI receptor and the Fc portion of human IgG. Atacicept inhibits B cell stimulation by binding to B lymphocyte stimulator and a proliferation-inducing ligand. Atacicept can be used in research of B-cell autoimmune disease [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: TACI-Ig; TACI-Fc 5. CAS No. 845264-92-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99446. | |
| Ataciguat | Ataciguat. Group: Biochemicals. Alternative Names: 5-Chloro-2-[[ (5-chloro-2-thienyl) sulfonyl]amino]-N-[4- (4-morpholinylsulfonyl) phenyl]benzamide; HMR 1766. Grades: Highly Purified. CAS No. 254877-67-3. Pack Sizes: 100mg. Molecular Formula: C21H19Cl2N3O6S3. US Biological Life Sciences. | Worldwide |
| Ataciguat | Ataciguat, formerly referred to as HMR-1766, a novel anthranilic acid derivative, is a potent guanylate cyclase activator. Ataciguat has potential to treat diseases associated with increased vascular tone combined with enhanced ROS production. Uses: Ataciguat, formerly referred to as hmr-1766, a novel anthranilic acid derivative, belongs to a new structural class of sgc activators capable of activating the oxidized form of sgc. ataciguat has been shown to improve endothelial function and to reduce p. Synonyms: HMR-1766; HMR 1766; HMR1766; Ataciguat; 5-Chloro-2-[[ (5-chloro-2-thienyl) sulfonyl]amino]-N-[4- (4-morpholinylsulfonyl) phenyl]benzamide; Ataciguat; HMR 1766. Grades: >98%. CAS No. 254877-67-3. Molecular formula: C21H19Cl2N3O6S3. Mole weight: 576.5. | |
| At-AFP1 | At-AFP1 is an antimicrobial peptide produced by Arabidopsis thaliana (Mouse-ear cress). It has antifungal activity against Alternaria brassicola (IC50=10 μg/ml), Botrytis cinerea (IC50=3.90 μg/ml), Fusarium culmorum (IC50=3 μg/ml), Fusarium oxysporum f.sp. lycopersici (IC50=3 μg/ml), Pyricularia oryzae (IC50=0.25 μg/ml) and Verticiliium dahliae (IC50=1.50 μg/ml). Synonyms: Defensin-like protein 13; Protein LCR67; Lys-Leu-Cys-Glu-Arg-Pro-Ser-Gly-Thr-Trp-Ser-Gly-Val-Cys-Gly-Asn-Ser-Asn-Ala-Cys-Lys-Asn-Gln-Cys-Ile-Asn-Leu-Glu-Lys-Ala-Arg-His-Gly-Ser-Cys-Asn-Tyr-Val-Phe-Pro-Ala-His-Lys-Cys-Ile-Cys-Tyr-Phe-Pro-Cys (Disulfide bridge: Cys3-Cys50, Cys14-Cys35, Cys20-Cys44, Cys24-Cys46). Grades: >98%. | |
| Atagabalin | Atagabalin, also referred to PD-0200,390, is a gabamimetic agent developed as a treatment for insomnia but was discontinued following unsatisfactory trial results. Synonyms: 2-[(3S,4S)-1-(aminomethyl)-3,4-dimethylcyclopentyl]acetic acid; (1-aminomethyl-3,4-dimethylcyclopentyl)acetic acid; PD 0200390; PD-0200390; PD0200390. Grades: >98%. CAS No. 223445-75-8. Molecular formula: C10H19NO2. Mole weight: 185.267. | |
| Atalafoline | Other Alkaloids. Alternative Names: 1,3-Dihydroxy-2,5,6-trimethoxy-10-methylacridin-9-one. CAS No. 107259-49-4. Mole weight: 331.32. Purity: 95%+. Catalog: ACM107259494. | |
| Atalantoflavone | Flavonoids. CAS No. 119309-02-3. Molecular formula: C20H16O5. Mole weight: 336.3. Appearance: Yellow powder. Purity: 0.98. IUPACName: 5-hydroxy-2-(4-hydroxyphenyl)-8,8-dimethylpyrano[2,3-h]chromen-4-one. Canonical SMILES: CC1 (C=CC2=C3C (=C (C=C2O1)O)C (=O)C=C (O3)C4=CC=C (C=C4)O)C. Catalog: ACM119309023. | |
| Ataluren | Ataluren (PTC124) is an orally available CFTR-G542X nonsense allele inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PTC124. CAS No. 775304-57-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-14832. | |
| Ataluren | Ataluren is an investigational new drug designed to enable the formation of a functioning protein in patients with genetic disorders due to a nonsense mutation. Ataluren is currently being investigated for use in patients with nonsense mutation Duchenne/Becker muscular dystrophy (nmDBMD) and cystic fibrosis (nmCF). Synonyms: PTC124; PTC-124; PTC 124. Grades: 0.98. CAS No. 775304-57-9. Molecular formula: C15H9FN2O3. Mole weight: 284.246. | |
| Ataluren impurities1 | Ataluren impurities1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 775304-03-5. Molecular Formula: C16H12N2O4. Mole Weight: 296.28. Catalog: APB775304035. |  |
| Ataluren impurities2 | Ataluren impurities2. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C15H10N2O4. Mole Weight: 282.26. Catalog: APB10918. | |
| Ataluren impurities3 | Ataluren impurities3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 775304-56-8. Molecular Formula: C15H9FN2O3. Mole Weight: 284.25. Catalog: APB775304568. | |
| Ataluren impurities4 | Ataluren impurities4. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C16H10N2O5. Mole Weight: 310.27. Catalog: APB10919. | |
| Ataluren impurities5 | Ataluren impurities5. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C15H8ClFN2O3. Mole Weight: 318.69. Catalog: APB10920. | |
| Ataluren impurities6 | Ataluren impurities6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 775304-60-4. Molecular Formula: C16H11FN2O3. Mole Weight: 298.27. Catalog: APB775304604. | |
| Atamestane | Atamestane is a synthetic steroidal substance with antineoplastic activity. Atamestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. Uses: Enzyme inhibitors. Synonyms: Atamestanum; Atamestano; Biomed-777; Biomed 777; Biomed777; CCRIS 6528; CCRIS6528; CCRIS-6528; SH-489; SH 489; SH489. CAS No. 96301-34-7. Molecular formula: C20H26O2. Mole weight: 298.43. | |
| Ataquimast | Ataquimast is used in curing advanced receptor-positive breast cancer. Ataquimast inhibits IL-5 secretion along with that of TNF-a, IL-4 and GM-CSF from human cells. Synonyms: 1-Ethyl-3-(methylamino) 2(1H)-quinoxalinone. CAS No. 182316-31-0. Molecular formula: C11H13N3O. Mole weight: 203.24. | |
| Atazanavir | 100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C38H52N6O7. CAS No. 198904-31-3. Prepack ID 89984074-100mg. Molecular Weight 704.86. See USA prepack pricing. |  |
| Atazanavir | Atazanavir is a novel and potent azapeptide protease inhibitor that specifically inhibits the human immunodeficiency virus type 1 (HIV-1) protease enzyme with inhibition constant Ki of 66 nmol/L and also inhibits the viral replication of HIV-1 with 50% effective concentration EC50 ranging from 2.6 to 5.3 nmol/L. Atazanavir binds to HIV-1 protease preventing the cleavage of gag and gag-pol polyproteins, which results in the formation of immature virions in HIV-1-infected cells. Atazanavir has a different C-2 symmetric chemical structure and a generally greater antiretroviral potency in various HIV strains compared to other protease inhibitors, including indinavir, nelfinavir, ritonavir, saquinavir and amprenavir. Synonyms: Atazanavir ; Reyataz ; Atazanavir sulfate ; CGP75136 ; CGP75176 ; CGP75355 ; BMS232632 ; CGP 73547 ; CGP 75136 ; CGP 75176 ; CGP 75355 ; CGP-73547 ; CGP-75136 ; CGP-75176 ; CGP-75355 ; BMS 232632 ; BMS-232632 ; BMS-232632-05 ; C413408. Grades: 0.98. CAS No. 198904-31-3. Molecular formula: C38H52N6O7. Mole weight: 704.869. | |
| Atazanavir | Atazanavir is a HIV-1 protease inhibitor, used in the anti-retroviral therapy of adult and sometimes paediatric patients infected with HIV. In in vitro studies with human pulmonary epithelial cells, atazanavir has been studied as a potential inhibitor of SARS-CoV-2 Mpro protease, with the aim of halting viral replication. Group: Biochemicals. Alternative Names: 3, 12-Bis (1, 1-dimethylethyl) -8-hydroxy-4, 11-dioxo-9- (phenylmethyl) -6-[[4- (2-pyridinyl) phenyl]methyl]-dimethyl ester; (3S,8S, 9S, 12S) -2, 5, 6, 13-Pentaazatetradecane dioic acid; BMS-232632. Grades: Highly Purified. CAS No. 198904-31-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C??H??N?O?, Molecular Weight: 704.86. US Biological Life Sciences. | Worldwide |
| Atazanavir | Atazanavir (BMS-232632) is a highly selective and orally active HIV-1 protease inhibitor. Atazanavir is a substrate and inhibitor of CYP3A4 , and an inhibitor of P-glycoprotein (P-gp). Atazanavir is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 3.49 μM. Atazanavir inhibits cardiac fibrosis, hyperlipidemia and induces malignant glioma death [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Natural products. Alternative Names: BMS-232632. CAS No. 198904-31-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17367. | |
| Atazanavir Bisulfate Salt | Atazanavir is a novel azapeptide HIV protease inhibitor (PI). Antiviral. Group: Biochemicals. Alternative Names: 3, 12-Bis (1, 1-dimethylethyl) -8-hydroxy-4, 11-dioxo-9- (phenylmethyl) -6-[[4- (2-pyridinyl) phenyl]methyl]-dimethyl Ester, (3S,8S, 9S, 12S) -2, 5, 6, 13-Pentaazatetradecane dioic Acid; BMS-232632; CGP-73547; Reyataz. Grades: Highly Purified. CAS No. 229975-97-7. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Atazanavir-d18 | 2H Labeled Compounds. CAS No. 1092540-52-7. Molecular formula: C38H34D18N6O7. Mole weight: 722.97. Catalog: ACM1092540527. | |
| Atazanavir-d5, Bisulfate Salt (3, 12-Bis (1, 1-dimethylethyl) -8-hydroxy-4, 11-dioxo-9- (phenylmethyl) -6-[[4- (2-pyridinyl) phenyl]methyl]-dimethyl Ester, (3S,8S, 9S, 12S) -2, 5, 6, 13-Pentaazatetradecane dioic acid-d5, BMS 232632-d5, CGP 73547-d5, Reyataz-d5) | Atazanavir is a novel azapeptide protease inhibitor (PI). Group: Biochemicals. Alternative Names: 3, 12-Bis (1, 1-dimethylethyl) -8-hydroxy-4, 11-dioxo-9- (phenylmethyl) -6-[[4- (2-pyridinyl) phenyl]methyl]-dimethyl Ester, (3S,8S, 9S, 12S) -2, 5, 6, 13-Pentaazatetradecane dioic acid-d5; BMS 232632-d5; CGP 73547-d5; Reyataz-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Atazanavir-d6 | Atazanavir-d6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1092540-50-5. Molecular Formula: C38H46D6N6O7. Mole Weight: 710.91. Catalog: APB1092540505. | |
| Atazanavir-d9 | 2H Labeled Compounds. CAS No. 1092540-51-6. Molecular formula: C38H43D9N6O7. Mole weight: 713.91. Catalog: ACM1092540516. | |
| Atazanavir Di-tert-butyl Analog | An impurity of Atazanavir. Synonyms: Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir. Grades: > 95%. CAS No. 198904-86-8. Molecular formula: C32H42N4O5. Mole weight: 562.72. | |
| Atazanavir EP Impurity A | Atazanavir EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(pyridin-2-yl)benzoic acid. CAS No. 4385-62-0. Molecular Formula: C12H9NO2. Mole Weight: 199.21. Catalog: APB4385620. | |
| Atazanavir EP Impurity B | Atazanavir EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(pyridin-2-yl)benzaldehyde. CAS No. 127406-56-8. Molecular Formula: C12H9NO. Mole Weight: 183.21. Catalog: APB127406568. | |
| Atazanavir EP Impurity D | Atazanavir EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,3S)-3-amino-4-phenyl-1-((E)-1-(4-(pyridin-2-yl)benzyl)-2-(4-(pyridin-2-yl)benzylidene)hydrazinyl)butan-2-ol. Molecular Formula: C34H33N5O. Mole Weight: 527.66. Catalog: APB03265. | |
| Atazanavir EP Impurity E (Atazanavir S,R,S,S-Diastereomer) | Atazanavir EP Impurity E (Atazanavir S,R,S,S-Diastereomer). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl ((5S,8S,9R,14S)-8-benzyl-5-(tert-butyl)-9-hydroxy-15,15-dimethyl-3,6,13-trioxo-11-(4-(pyridin-2-yl)benzyl)-2-oxa-4,7,11,12-tetraazahexadecan-14-yl)carbamate. Molecular Formula: C38H52N6O7. Mole Weight: 704.86. Catalog: APB03264. | |
| Atazanavir EP Impurity F (Atazanavir R,S,S,S-Diastereomer) | Atazanavir EP Impurity F (Atazanavir R,S,S,S-Diastereomer). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl ((5S,8S,9S,14R)-8-benzyl-5-(tert-butyl)-9-hydroxy-15,15-dimethyl-3,6,13-trioxo-11-(4-(pyridin-2-yl)benzyl)-2-oxa-4,7,11,12-tetraazahexadecan-14-yl)carbamate. CAS No. 1332981-14-2. Molecular Formula: C38H52N6O7. Mole Weight: 704.86. Catalog: APB1332981142. | |
| Atazanavir EP Impurity G (Atazanavir S,S,S,R-Diastereomer) | Atazanavir EP Impurity G (Atazanavir S,S,S,R-Diastereomer). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl ((5R,8S,9S,14S)-8-benzyl-5-(tert-butyl)-9-hydroxy-15,15-dimethyl-3,6,13-trioxo-11-(4-(pyridin-2-yl)benzyl)-2-oxa-4,7,11,12-tetraazahexadecan-14-yl)carbamate. CAS No. 1332981-16-4. Molecular Formula: C38H52N6O7. Mole Weight: 704.86. Catalog: APB1332981164. | |
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