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A metabolite of Adenosine, a multifunctional nucleoside triphosphate used in cells as a coenzyme of intracellular energy transfer. It transports chemical energy within cells for metabolism. Synonyms: ATP Disodium Hydrate; ATP Disodium Salt Hydrate; Adetphos Hydrate; Disodium ATP Hydrate; Disodium Adenosine 5'-Triphosphate Hydrate; Disodium Adenosine-5'-triphosphoric Acid Hydrate; Disodium Dihydrogen ATP Hydrate. Grade: 96%. CAS No. 34369-07-8. Molecular formula: C10H14N5Na2O13P3 x(H2O). Mole weight: 551.14.
Adenosine 5-Triphosphate Disodium Salt Hydrate
A metabolite of Adenosine, a multifunctional nucleoside triphosphate used in cells as a coenzyme of intracellular energy transfer. It transports chemical energy within cells for metabolism. Group: Biochemicals. Alternative Names: Adenosine 5'-(Tetrahydrogen Triphosphate) Disodium Salt Hydrate; ATP Disodium Hydrate; ATP Disodium Salt Hydrate; Adetphos Hydrate; Disodium ATP Hydrate; Disodium Adenosine 5'-Triphosphate Hydrate; Disodium Adenosine-5'-triphosphoric Acid Hydrate; Disodium Dihydrogen ATP Hydrate. Grades: Highly Purified. CAS No. 34369-07-8,987-65-5,56-65-5,51963-61-2. Pack Sizes: 25g, 50g, 100g, 250g. Molecular Formula: C??H??N?Na?O??P? x(H?O). US Biological Life Sciences.
Worldwide
Adenosine-5'-triphosphate disodium salt trihydrate
5g Pack Size. Group: Analytical Reagents, Biochemicals, Diagnostic Raw Materials. Formula: C10H14N5O13P3Na2 · xH2O. CAS No. 51963-61-2. Prepack ID 49306151-5g. Molecular Weight 551.14. See USA prepack pricing.
Adenosine-5'-triphosphate disodium salt trihydrate 98+% (HPLC)
Adenosine-5'-triphosphate disodium salt trihydrate 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100g, 250g, 25g, 5g, 1Kg. US Biological Life Sciences.
Adenosine 5?-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is use in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger cAMP. ATP provides the metabolic energy to drive metabolic pumps. ATP serves as a coenzyme in a wide array of enzymatic reactions. Group: Biochemicals. Alternative Names: ATP 2Na; ATP disodium salt. Grades: Molecular Biology Grade. CAS No. 51963-61-2. Pack Sizes: 5g, 25g, 100g, 500g. Molecular Formula: C10H14N5O13P3Na2 3H2O, Molecular Weight: 605.19. US Biological Life Sciences.
Worldwide
Adenosine 5'-triphosphate magnesium salt
Adenosine 5'-triphosphate magnesium salt, a crucial molecule in cellular metabolism, serves as the main carrier of energy within cells. It has proven useful in treating heart conditions, metabolic syndrome, and even muscular dystrophy. As a salt form of ATP, its stability and solubility are enhanced, making it an invaluable tool for biochemical research. Its indispensable role in vital processes calls for fervent exploration and deeper understanding. Synonyms: ATP magnesium salt. Grade: 95%. CAS No. 74804-12-9. Molecular formula: C10H14MgN5O13P3. Mole weight: 529.47.
Adenosine 5?-Triphosphate Magnesium Salt (ATP)
Adenosine 5y-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is use in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger cAMP. ATP provides the metabolic energy to drive metabolic pumps. ATP serves as a coenzyme in a wide array of enzymatic reactions. Group: Biochemicals. Alternative Names: ATP magnesium salt. Grades: Highly Purified. CAS No. 74804-12-9. Pack Sizes: 100mg, 500mg, 1g. Molecular Formula: C10H16N5O13P3·xMg2+, Molecular Weight: 529.47. US Biological Life Sciences.
Worldwide
Adenosine 5'-triphosphate potassium salt
Adenosine 5'-triphosphate potassium salt is an indispensable biomolecular compound, serving as a fundamental energy reservoir for various intracellular mechanisms and a pivotal transmitter. Its involvement spans a spectrum of biochemical phenomena encompassing muscular flexion and neurotransmission. CAS No. 42373-41-1. Molecular formula: C10H14K2N5O13P3. Mole weight: 583.36.
Adenosine 5'-Triphosphate-P'',P'',P'',P'-oxy-18O4 Disodium Salt
Adenosine 5'-Triphosphate-P'',P'',P'',P'-oxy-18O4 Disodium Salt, is the labeled analogue of Adenosine 5'-Triphosphate Disodium Salt. These compounds can be used in studies of Kinases without using purified enzyme or a fluorescent substrate. Molecular formula: C10H14N5Na2O9[18O]4P3. Mole weight: 559.14.
Adenosine 5-Triphosphate-P'',P'',P'',P'-oxy-18O4 Disodium Salt
Adenosine 5'-Triphosphate, disodium salt is a p2 purinergic (P2X and P2Y) agonist that increases Ca2+-activated K+ channel activity. It has been found to induce a release of prostoglandin D2 and histamine from rat peritoneal mast cells in a dose-dependent manner. Applications: A p2 purinergicagonist. Group: Coenzymes. Synonyms: ATP disodium salt. CAS No. 987-65-5. Purity: ≥98%. Mole weight: 551.14. Appearance: Powder. Form: Solid. ATP disodium salt; Adenosine 5'-Triphosphate, disodium salt; 987-65-5. Cat No: COEC-004.
Adenosine 5'-triphosphate trisodium salt
Adenosine 5'-triphosphate trisodium salt is a vital compound widely used in the biomedical industry. It serves as an essential energy carrier and intracellular signaling molecule. ATP trisodium salt is commonly utilized in research and enzymatic assays requiring ATP supplementation. Synonyms: 5'-ATP Na3; Adenosine, 5'-(tetrahydrogen triphosphate), trisodium salt; ATP trisodium salt. Grade: ≥95% by HPLC. CAS No. 20978-32-9. Molecular formula: C10H13N5Na3O13P3. Mole weight: 573.13.
ADENOSINE-8-14C 5'-MONOPHOSPHATE DIAMMONIUM SALT
ADENOSINE-8-14C 5'-MONOPHOSPHATE DIAMMONIUM SALT. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ADENOSINE-8-14C 5'-MONOPHOSPHATE DIAMMONIUM SALT;ADENOSINE 5' MONOPHOSPHATE DIAMMONIUM SALT [8-14C];ADENOSINE-8-14C 5'-MONOPHOSPHATE*AMMONIU M. Product Category: Heterocyclic Organic Compound. CAS No. 134907-91-8. Molecular formula: C9H18N7O7P. Mole weight: 369.27. Product ID: ACM134907918. Alfa Chemistry ISO 9001:2015 Certified.
Adenosine-8(3)H 3',5'-cyclic monophosphate
Adenosine-8(3)H 3',5'-cyclic monophosphate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ADENOSINE-8(3)H 3',5'-CYCLIC MONOPHOSPHATE;Cyclic AMP-8-3H. Product Category: Heterocyclic Organic Compound. CAS No. 50816-76-7. Molecular formula: C10H11N5O6PT. Mole weight: 331.21. Product ID: ACM50816767. Alfa Chemistry ISO 9001:2015 Certified.
In the extracellular space, ecto-5?-nucleotidase (CD73) dephosphorylates adenosine triphosphate (ATP) to produce adenosine. Adenosine has four receptors namely A1R, A2AR A2BR and A3R. Adenosine plays a key role in the osteogenic differentiation. A1R induces osteoclast differentiation and A2AR induces osteoblast differentiation. Adenosine has been used: as a supplement in embryonic type culture medium for in vitro osteogenic differentiation for evaluation of its effect on cell survival by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT assay) and cell proliferation by 3H-thymidine incorporation assay in multi drug resistant glioblastoma stem-like cells (GSCs), and as a standard in high performance liquid chromatography (HPLC). as a constituent in collagenase solution for the collagenase digestion of mice fat tissue. Group: Biochemicals. Alternative Names: 9- β-D-Ribofuranosyl-9H-purin-6-amine; 9- β-D-Ribofuranosyladenine; Adenine Riboside; Adenocard; Adenocor; Adenogesic; Adenoscan; Adrekar; Boniton; D-Adenosine; 1-(6-Amino-9H-purin-9-yl)-1-deoxy- β-D-ribofuranose; Myocol; NSC 7652. Grades: Molecular Biology Grade. CAS No. 58-61-7. Pack Sizes: 100g, 500g. Molecular Formula: C10H13N5O4, Molecular Weight: 267.25. US Biological Life Sciences.
A potent and selective agonist of adenosine A1 receptor (A1R) (Ki = 2.3nM, 790nM, 18.6uM, 43nM for human A1, A2A, A2B, and A3, respectively). Group: Biochemicals. Grades: Highly Purified. CAS No. 41552-82-3. Pack Sizes: 25mg. US Biological Life Sciences.
An adenosine analog that acts as a selective, high affinity agonist for Adenosine A1 receptor (A1R) (Ki = 800 pM; 2.3uM, 18.8uM, and 42nM for human A1, A2A, A2B, A3 respectively). Shown to be centrally active following systemic administration and exhibits anti-convulsive effects. Also reported to inhibit adenylate cyclase activity in rat fat cell membrane (IC50 = 33nM). Diminishes respiratory rhythm, reduces heart rate, and enhances the activity of KATP channels. Reduces norepinephrine release by about 50% in untreated and pertussis toxin treated hearts.CAS Number:37739-05-2. Group: Biochemicals. Grades: Highly Purified. CAS No. 37739-05-2. Pack Sizes: 10mg. Molecular Formula: C??H??ClN?O?. US Biological Life Sciences.
Worldwide
Adenosine A1 Receptor Antagonist I, DPCPX (8-Cyclopentyl-1,3-dipropylxanthine, CPX, PD-116,948)
A blood-brain barrier permeable xanthine derivative that acts as a highly selective antagonist of Adenosine A1 receptor (A1R; Ki = 3.9nM, 130nM, 1.0uM, 4.0uM for human A1, A2A, A2B, and A3 respectively). Exhibits about 1,000-fold higher affinity and a 30-fold greater selectivity for A1R when compared to theophylline. Shown to competitively antagonize the inhibition of adenylate cyclase activity via A1 adenosine receptors in rat fat cells and the stimulation of adenylate cyclase via A2 adenosine receptors in human platelets. Exhibits hypertensive properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 102146-07-6. Pack Sizes: 25mg. Molecular Formula: C??H??N?O?, Primary Target: A1. US Biological Life Sciences.
A blood-brain barrier-permeant indenopyrimidinone that acts as a dual A1/A2A antagonist (Ki = 48.2 and 6.5nM, respectively, against agonist-induced cAMP response in A1- or A2A-expressing CHO-K1 cells) and effectively reverses D2 antagonist haloperidol- (1mg/kg; s.c.) induced catalepsy in both rats and mice (ED50 = 0.3 and <0.1mg/kg, respectively) in vivo by simultaneously reversing A1-mediated inhibition of DA (Dopamine) release and A2A-dependent inhibition of D2 receptor response to DA. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Adenosine A 2A/A? Receptor Antagonist
The Adenosine A2A/A? Receptor Antagonist controls the biological activity of Adenosine A2A/A? Receptor. This small molecule/inhibitor is primarily used for Biochemicals applications. Group: Fluorescence/luminescence spectroscopy.
Adenosine A2A Receptor Agonist I, Hydrochloride (CGS 21680)
A xanthin derivative that acts as a potent agonist of adenosine A2A receptors (Ki = 27nM). Exhibits reduced affinity for A2B receptors (Ki = 67nM), but offers greater selectivity over A1R (Ki = 290nM) and A3R (88.8uM). Exerts an anti-inflammatory effect during chronic inflammation and ameliorates the tissue damage associated with collagen-induced arthritis. Also shown to reduce CCR7 Protein Expression in THP1 macrophages. Shown to delay the progressive deterioration of motor performance and prevent a reduction in brain weight in murine model of Huntington's disease. Group: Biochemicals. Alternative Names: CGS-21680; 3- (4- (2- ( (6-amino-9- ( (2R, 3R, 4S, 5S) -5- (ethylcarbamoyl) -3, 4-di hydroxytetra hydrofuran-2-yl) -9H-purin-2-yl) amino) ethyl) phenyl) propanoic acid). Grades: Highly Purified. CAS No. 124182-57-6. Pack Sizes: 5mg. Molecular Formula: C23H29N7O6 HCl, Molecular Weight: 536. US Biological Life Sciences.
Worldwide
Adenosine A2A Receptor Antagonist II, SCH-58261 (2-(furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, SCH58261, SCH 58261)
A highly potent and selective antagonist of adenosine A2A receptor (Ki = 600pM). Does not affect the activity of other adenosine receptors in any significant manner (Ki = 287nM; 5uM, and > 10uM for A1, A2B, and A3 receptors, respectively). Displays neuroprotective effects in cerebral ischaemia in rats, and shown to counteract Parkinsonian-like muscle rigidity in rats. CAS Number:160098-96-4. Group: Biochemicals. Grades: Highly Purified. CAS No. 160098-96-4. Pack Sizes: 10mg. Molecular Formula: C??H??N?O, Primary Target: A2A Receptor. US Biological Life Sciences.
A pyridine derivative that acts as a highly selective antagonist of A3 receptor with excellent potency in both humans and rodents (Ki = 18.9nM for human A3R, and 113nM for rat A3R). Exhibits only a trivial antagonistic activity towards A1 and A2A receptors (Ki = 15.6uM and 2.05uM for rat A1R and A2AR, respectively). Abolishes the agonistic effects of Cl-IB-MECA on A3R-mediated proliferation of primary human coronary smooth muscle cells. Also, reported to block NECA-induced bronchoconstriction in an allergic murine model. Group: Biochemicals. Grades: Highly Purified. CAS No. 212329-37-8. Pack Sizes: 5mg. Molecular Formula: C??H??NO?S. US Biological Life Sciences.
Worldwide
Adenosine amine congener
Adenosine amine congener is a water-soluble and potent A1 adenosine receptor agonist. Synonyms: N-(4-(2-((4-(2-((2-Aminoethyl)amino)-2-oxoethyl)phenyl)amino)-2-oxoethyl)phenyl)adenosine. Grade: 98%. CAS No. 96760-69-9. Molecular formula: C28H32N8O6. Mole weight: 576.6.
Adenosine Cyclic 2',3'-Phosphate 5'-Phosphate can be used in biological study for 2':3'-cyclic PAP, sulfuryl group acceptor in a reaction catalyzed by phenol sulfotransferase. It can also be used in biological study for effect of adenine nucleotides on myo-inositol-1,4,5-trisphosphate-induced calcium release. Group: Biochemicals. Grades: Highly Purified. CAS No. 4527-92-8. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C10H13N5O9P2, Molecular Weight: 409.19. US Biological Life Sciences.
Worldwide
Adenosine-d14 5?-triphosphate disodium salt solution
?98 atom % D, ?95% (CP), 100 mM (in 5mM Tris / D2O). Group: Fluorescence/luminescence spectroscopy.
Adenosine-d2
Adenosine-d 2 is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physio. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Adenine riboside-d2; D-Adenosine-d2. CAS No. 82741-17-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-B0228S6.
adenosine deaminase
Adenosine Deaminase (also known as adenosine aminohydrolase, or ADA) is an enzyme (EC 3.5.4.4) involved in purine metabolism. It is needed for the breakdown of adenosine from food and for the turnover of nucleic acids in tissues. Group: Enzymes. Synonyms: deoxyadenosine deaminase. Enzyme Commission Number: EC 3.5.4.4. CAS No. 9026-93-1. ADA. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4568; adenosine deaminase; EC 3.5.4.4; 9026-93-1; deoxyadenosine deaminase. Cat No: EXWM-4568.
Adenosine deaminase Bovine, Recombinant
Adenosine deaminase is an enzyme (EC 3.5.4.4) involved in purine metabolism. It is needed for the breakdown of adenosine from food and for the turnover of nucleic acids in tissues. Present in virtually all mammalian cells, its primary function in Humans is the development and maintenance of the immune system. Protein determined by biuret. Applications: Adenosine deaminase is useful in various molecular biology assays, such as glycerol release assays. adenosine deaminase is a potential target for treatments of combined immunodeficiency disease. Group: Enzymes. Synonyms: ADA; adenosine deaminase; adenosine aminohydrolase; 9026-93-1; EC 3.5.4.4. Enzyme Commission Number: EC 3.5.4.4. CAS No. 9026-93-1. ADA. Mole weight: 32.5-33 kDa. Activity: 60-130 units/mg protein; > 130 units/mg protein; 150-200 units/mg protein. Storage: 2-8°C. Form: ammonium sulfate suspension. Suspension in 3.2 M (NH4)2SO4, 0.01 M potassium phosphate, pH 6.0. Source: E. coli. Species: Bovine. ADA; adenosine deaminase; adenosine aminohydrolase; 9026-93-1; EC 3.5.4.4. Cat No: NATE-0032.
Adenosine deaminase chicken, recombinant
recombinant, expressed in E. coli, ?0.5 U/mL. Group: Fluorescence/luminescence spectroscopy.
Adenosine deaminase from Human, Recombinant
Adenosine deaminase is an enzyme (EC 3.5.4.4) involved in purine metabolism. It is needed for the breakdown of adenosine from food and for the turnover of nucleic acids in tissues. Present in virtually all mammalian cells, its primary function in Humans is the development and maintenance of the immune system. Applications: Adenosine deaminase (ada) is a key enzyme in purine metabolism and is essential for normal immune function. it is important in the study of immune system diseases such as rheumatoid arthritis. Group: Enzymes. Synonyms: ADA; adenosine deaminase; adenosine aminohydrolase; 9026-93-1; EC 3.5.4.4. Enzyme Commission Number: EC 3.5.4.4. CAS No. 9026-93-1. ADA. Activity: >1 U/mL. Storage: Store at -20°C. Source: E. coli. Species: Human. ADA; adenosine deaminase; adenosine aminohydrolase; 9026-93-1; EC 3.5.4.4. Cat No: NATE-1583.
Adenosine Deaminase Inhibitor, DCF - CAS 53910-25-1
The Adenosine Deaminase Inhibitor, DCF, also referenced under CAS 53910-25-1, controls the biological activity of Adenosine Deaminase. Group: Fluorescence/luminescence spectroscopy.
Adenosine deaminase, microorganism
Adenosine deaminase (RnADA) (EC 3.5.4.4) is an enzyme that catalyzes the irreversible deamination of adenosine and 2'-deoxyadenosine to inosine and 2'-deoxyinosine, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RnADA. CAS No. 9026-93-1. Pack Sizes: 1 mg. Product ID: HY-114175.
Adenosine deaminase, Recombinant
Adenosine deaminase is an enzyme (EC 3.5.4.4) involved in purine metabolism. It is needed for the breakdown of adenosine from food and for the turnover of nucleic acids in tissues. Present in virtually all mammalian cells, its primary function in Humans is the development and maintenance of the immune system. Group: Enzymes. Synonyms: ADA; adenosine deaminase; adenosine aminohydrolase; 9026-93-1; EC 3.5.4.4. Enzyme Commission Number: EC 3.5.4.4. CAS No. 9026-93-1. Purity: > 90 %. ADA. Mole weight: About 53kDa (SDS-PAGE). Activity: 200U/mg protein. Appearance: White powder, lyophilized. Storage: Redissolved in 20% glycerol, 4°C, store at -20°C for long-term preservation, Avoid multiple freeze-thaw cycles. Source: E. coli. ADA; adenosine deaminase; adenosine aminohydrolase; 9026-93-1; EC 3.5.4.4. Cat No: NATE-1009.
Adenosine dialdehyde
Adenosine dialdehyde is an irreversible inhibitor of S-adenosylhomocysteine hydrolase (IC50 = 40 nM), blocking the conversion of SAH to homocysteine and adenosine. Synonyms: 2-[1-(6-aminopurin-9-yl)-2-oxoethoxy]-3-hydroxypropanal. Grade: ≥ 95 %. CAS No. 34240-05-6. Molecular formula: C10H11N5O4. Mole weight: 265.23.
Adenosine: h2o
Adenosine: h2o. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Adenosine 15N; Adenosine-15N. Product Category: Heterocyclic Organic Compound. CAS No. 41547-82-4. Molecular formula: ClH. Mole weight: 36.46094;g/mol. Purity: 0.96. IUPACName: chlorane. Canonical SMILES: Cl. ECNumber: 231-595-7. Product ID: ACM41547824. Alfa Chemistry ISO 9001:2015 Certified.
Adenosine HCl
Adenosine hydrochloride is a hydrochloride salt form of adenosine, a nucleoside composed of adenine and ribose. Adenosine plays a crucial role in biochemical processes such as energy transfer (e.g., ATP) and signal transduction as a neurotransmitter. In its monohydrochloride form, adenosine is more soluble in water, making it useful for various biochemical and pharmaceutical applications. This compound is employed in research focused on cellular metabolism, enzyme functions, and nucleic acid interactions. Additionally, adenosine monohydrochloride is used in studies investigating the effects of adenosine on cardiovascular and neurological functions. Synonyms: Adenosine hydrochloride; Adenosine hydrochloride (1:x); (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol hydrochloride; 9-β-D-Ribofuranosyl-9H-purin-6-amine hydrochloride; 9-β-D-Ribofuranosyladenine hydrochloride; D-Adenosine hydrochloride; Adenine riboside hydrochloride; β-D-Adenosine hydrochloride; β-Adenosine hydrochloride. Grade: ≥98% by HPLC. CAS No. 58056-57-8. Molecular formula: C10H13N5O4.xHCl. Mole weight: 267.24 (free base).
Adenosine impurity 18
Adenosine impurity 18. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10527-91-0. Molecular formula: C9H9N5O2. Mole weight: 219.2. Catalog: APB10527910.
Adenosine impurity 24
Adenosine impurity 24. Uses: For analytical and research use. Group: Impurity standards. CAS No. 141344-03-8. Molecular formula: C11H14N6O3. Mole weight: 278.27. Catalog: APB141344038.
adenosine kinase
2-Aminoadenosine can also act as acceptor. Group: Enzymes. Synonyms: adenosine kinase (phosphorylating). Enzyme Commission Number: EC 2.7.1.20. CAS No. 9027-72-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3034; adenosine kinase; EC 2.7.1.20; 9027-72-9; adenosine kinase (phosphorylating). Cat No: EXWM-3034.
Adenosine Kinase from Human, Recombinant
E.coli. Applications: Human adenosine kinase is an active and purified, 345-aa short form adk protein (39kda) cloned by rt-pcr amplification of mrna extracted from human hepatoma cells and expressed in e.coli. the sequence of the cloned adk (genbank accession number u50196) was confirmed by dna sequencing (100% identity). Group: Enzymes. Synonyms: ADK. Enzyme Commission Number: EC 2.7.1.20. CAS No. 9027-72-9. Mole weight: 39kDa. Activity: ≥ 0.200 unit/mg protein. Source: Human. Species: ADK. ADK; EC 2.7.1.20. Pack: stable lyophilized form. Cat No: NATE-1740.
Adenosine monophosphate
Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: AMP. CAS No. 61-19-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-A0181.
Adenosine monophosphate-13C10,15N5 disodium
Adenosine monophosphate-13C10,15N5 (AMP-13C10,15N5) disodium is 13C and 15N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction[1][2][3]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: AMP-13C10,15N5 disodium. Pack Sizes: 1 mg (100 mM in 25.19 ?L Tris HCl/H2O buffer). Product ID: HY-A0181BS.
Adenosine monophosphate 15N4
Adenosine monophosphate 15N4 is a labelled adenosine monophosphate. Adenosine monophosphate is a nucleotide used in the formation of RNA. Synonyms: Adenosine 5'-Monophosphate-15N4. Grade: 95% by HPLC; 98% atom 15N. Molecular formula: C10H14N5O7P. Mole weight: 351.26.
Adenosine monophosphate-15N5 dilithium
Adenosine monophosphate-15N5 dilithium is the 15N labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction[1][2][3]. Uses: Scientific research. Group: Isotope-labeled compounds. Pack Sizes: 5 mg (100 mM in 137 ?L Tris HCl/H2O buffer pH=7.5); 10 mg (100 mM in 275 ?L Tris HCl/H2O buffer pH=7.5). Product ID: HY-A0181S1.
Adenosine Monophosphate (mixture of 2(3)-phosphate isomers)
An adenosine derivative that is a metabolite of adenosine-2:3-cyclic monophopshate. Group: Biochemicals. Alternative Names: 2(3')-Adenylic acid; 2(3')-AMP; Adenosine 2(3')-(Dihydrogen Phosphate); Adenosine 2(3')-Phosphate; NSC 210570. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Adenosine Monophosphate (mixture of 2'(3')-phosphate isomers)-13C5 Sodium Salt
Adenosine N1-oxide, a compelling anti-inflammatory compound, used for studying diverse inflammatory ailments including asthma, rheumatoid arthritis, and inflammatory bowel disease. Synonyms: Adenosine, 1-oxide; 6-Amino-9-β-D-ribofuranosyl-9H-purine 1-oxide; Adenosine N-oxide; Adenosine-1-N-oxide; NSC 128561; (2R,3R,4S,5R)-2-(6-amino-7-oxidopurin-7-ium-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol. Grade: ≥95%. CAS No. 146-92-9. Molecular formula: C10H13N5O5. Mole weight: 283.24.
Adenosine N1-Oxide-[15N]
Adenosine N1-Oxide-[15N] is the labelled analogue of Adenosine N1-Oxide. Adenose N-Oxide and its derivatives are used as active ingredients in the preparation of therapeutic agents for inflammatory diseases and inhibitors of adenosine kinase. Synonyms: Adenosine-15N N1-Oxide; 6-Amino-9-β-D-ribofuranosyl-9H-purine-15N 1-Oxide; Adenosine-15N N-Oxide; NSC 128561-15N; (N6-15N)Adenosine1-oxide; Adenosine-N6-15N, 1-oxide. Grade: ≥90%. CAS No. 197227-85-3. Molecular formula: C10H13N4[15N]O5. Mole weight: 284.23.
Adenosine N-benzoyl-3'-deoxy-2'-O-(1,1-difluoro-2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a cutting-edge and highly effective modified nucleoside utilized in advanced biomedical research. With a distinctive and intricate chemical arrangement, it possesses unparalleled potential in gene therapies and drug delivery systems. This nucleoside has shown promising outcomes in the treatment and study of various genetic disorders and diseases, including cancer. Its exceptional stability and efficiency are beneficial in advancing research in these fields. Synonyms: ((2S,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-4-(1,1-difluoro-2-methoxyethoxy)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299279-70-0. Molecular formula: C49H55F2N8O7P. Mole weight: 936.98.
Adenosine, N-benzoyl-3'-deoxy-2'-O-(2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino] is a versatile and noteworthy biochemical compound extensively employed within the biomedical industry for the research of diverse ailments such as cancers. Synonyms: N-Benzoyl-3'-deoxy-2'-O-(2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]adenosine. CAS No. 2299278-12-7. Molecular formula: C40H40N6O6. Mole weight: 700.78.
Adenosine, N-benzoyl-3'-deoxy-2'-O-(2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a potent phosphoramidite recompound widely employed for the research of modified oligonucleotides, particularly in the development of nucleotide-based drugs targeting specific diseases such as cancer, viral infections and genetic disorders. Synonyms: ((2S,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-4-(2-methoxyethoxy)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299277-93-1. Molecular formula: C49H57N8O7P. Mole weight: 901.
Adenosine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-2-propen-1-yl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is an exceptional compound used in the research of formidable malignancies, such as lymphoma and leukemia. Its utilization in the pursuit of innovative antiviral therapeutics that specifically target RNA viruses denotes its indispensable role. Synonyms: ((2S,3R,4R,5R)-4-(allyloxy)-5-(6-benzamido-9H-purin-9-yl)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299282-94-1. Molecular formula: C49H55N8O6P. Mole weight: 882.98.
Adenosine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-methyl-, 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI) is a complex chemical entity employed in the synthesis of oligonucleotides targeting viral infections and various cancers. The versatility of this remarkable molecule extends beyond biomedical research and treatment; it has the potential to alter genetic sequences, thereby opening new therapeutic avenues for myriad hitherto enigmatic human ailments. Its designation as a universally valuable synthetic building block in both academic and clinical milieus underscores its indispensability in biomedicine. Synonyms: ((2S,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-4-methoxy-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 329773-22-0. Molecular formula: C47H53N8O6P. Mole weight: 856.95.
Adenosine (N-Bz)
Adenosine (N-Bz) is an essential biomedical compound widely employed in the research of numerous cardiovascular disorders, comprising arrhythmias and angina pectoris. It can interact with adenosine receptors. Grade: ≥ 98% by HPLC. Molecular formula: C17H17N5O5. Mole weight: 371.35.
Adenosine (N-PAC)
Adenosine (N-PAC), a pharmaceutical-grade compound, is a multifaceted agent, possessing the ability to treat various cardiovascular disorders: arrhythmias, angina, and hypertension. Mechanistically, its mechanism of action lies in selectively inducing the activation of specific receptors in the heart. Its downstream effects manifest as a non-negligible reduction in heart rate, accompanied by a reciprocal elevation in blood flow. Additionally, Adenosine (N-PAC) has utility in the diagnosis and treatment of certain types of irregular heartbeats, serving as an invaluable tool in the evaluation of blood circulation in cardiac imaging. Grade: ≥ 98% by HPLC. Molecular formula: C18H19N5O6. Mole weight: 401.37.
Adenosine N-phosphate 5'-phosphosulfate lithium salt
Adenosine N-phosphate 5'-phosphosulfate lithium salt is an indispensable compound prevalent in the biomedical field, exhibiting its significant relevance in the research and development of sulfated glycosaminoglycans, integral constituents of connective tissues. Additionally, it serves as an appreciable substrate for enzymes participating in compound metabolism and detoxification mechanisms. Synonyms: Sulfuric acid, 5'-anhydride with N-phosphono-5'-adenylic acid, lithium salt (1:x); Sulfuric acid, 5'-anhydride with N-phosphono-5'-adenylic acid, lithium salt; N-Phosphoadenosine-5'-phosphosulfate lithium salt. Grade: ≥98%. CAS No. 109434-21-1. Molecular formula: C10H15N5O13P2S.xLi. Mole weight: 507.26 (free acid).
adenosine nucleosidase
Also acts on adenosine N-oxide. Group: Enzymes. Synonyms: adenosinase; N-ribosyladenine ribohydrolase; adenosine hydrolase; ANase. Enzyme Commission Number: EC 3.2.2.7. CAS No. 9075-41-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3989; adenosine nucleosidase; EC 3.2.2.7; 9075-41-6; adenosinase; N-ribosyladenine ribohydrolase; adenosine hydrolase; ANase. Cat No: EXWM-3989.
adenosine-phosphate deaminase
Acts on AMP, ADP, ATP, NAD+ and adenosine, in decreasing order of activity. The bacterial enzyme can also accept the deoxy derivatives. cf. EC 3.5.4.6, AMP deaminase. Group: Enzymes. Synonyms: adenylate deaminase; adenine nucleotide deaminase; adenosine (phosphate) deaminase. Enzyme Commission Number: EC 3.5.4.17. CAS No. 37289-20-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4543; adenosine-phosphate deaminase; EC 3.5.4.17; 37289-20-6; adenylate deaminase; adenine nucleotide deaminase; adenosine (phosphate) deaminase. Cat No: EXWM-4543.
A cell-permeable adenosine analog that acts a potent non-selective agonist of adenosine receptors (Ki = 14nM, 20nM, 2.4uM and 6.2nM for A1, A2A, A2B, A3, respectively). Increases intracellular cAMP production (EC50 = 3.1uM in A2B expressing CHO cells). Shown to increase glucagon release in a dose-dependent manner and inhibit insulin release at low concentrations. Although at higher concentration some insulin release is observed. Also, displays a wide range adenosine-dependent effects, such as blocking platelet aggregation and inhibiting DNA synthesis. When administered at reperfusion, it is shown reduce infarction and block the formation of the mitochondrial permeability transition pore by activating p70S6 kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 35920-39-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Adenosine receptor antagonist 1
Adenosine receptor antagonist 1 is an A2aR-selective antagonist with an IC50 of 0.29 nM and displays 14-fold more selectivity for A2aR than A2bR. Synonyms: AKOS040757963; 2682930-40-9. CAS No. 2682930-40-9. Molecular formula: C22H15ClFN7O. Mole weight: 447.85.
Adenosine receptor antagonist 2
Adenosine receptor antagonist 2 is an orally active A2a/A2b adenosine receptor antagonist with IC 50 s of 1 nM and 3 nM, respectively. Adenosine receptor antagonist 2 has anti-tumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2703054-47-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144064.
Adenosine receptor antagonist 3
Adenosine receptor antagonist 3 is a potent antagonist of adenosine receptor. Adenosine receptor antagonist 3 has the potential for the research of cancer disease (extracted from patent WO2019233994A1, compound 1) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2400864-80-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144419.
Adenosine receptor inhibitor 1
Adenosine receptor inhibitor 1 is a potent and selective adenosine receptor (AR) inhibitor with K i values of >1000, 68.5, >1000, >1000 nM for A 1 AR, A 2A AR, A 2B AR, A 3 AR, respectively. Adenosine receptor inhibitor 1 shows antinociceptive activity, anti-inflammatory effect and peripheral analgesic effect. Adenosine receptor inhibitor 1 has the potential for the research of cancer or neurodegenerative diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2550400-52-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-147907.