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| Product | Description | |
|---|---|---|
| Alofanib | Alofanib, also known as RPT835, is a potent and selective allosteric inhibitor of FGFR2 with potential anticancer activity. Alofanib blocks the extracellular part of the receptor and prevents its binding with the ligand. Synonyms: RPT835; RPT-835; RPT 835; Alofanib. Grade: 95%. CAS No. 1612888-66-0. Molecular formula: C19H15N3O6S. Mole weight: 413.404. |  |
| Alogabat | Alogabat is a potent GABAA receptor positive allosteric modulator. Synonyms: 6-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazol-4-yl]methoxy}-N-(oxan-4-yl)pyridazine-3-carboxamide. Grade: 98% by HPLC. CAS No. 2230009-48-8. Molecular formula: C21H23N5O4. Mole weight: 409.44. | |
| Alogabat | Alogabat (example 8) is a GABA A α5 receptor positive allosteric modulators (PAMs) (extracted from patent WO2018104419A1) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RG-7816; RO-7017773. CAS No. 2230009-48-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-132806. |  |
| Alogliptin | Alogliptin (SYR-322 free base) is a potent, selective and orally active inhibitor of DPP-4 with an IC 50 of <10 nM, and exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9. Alogliptin can be used for the research of type 2 diabetes [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SYR-322 free base. CAS No. 850649-61-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0023A. | |
| Alogliptin | Alogliptin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Vipidia (TN); SYR 322; Alogliptin (Benzoate); alogliptin monobenzoate; 2-[[6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxopyrimidin-1-yl]methyl]benzonitrile,benzoic acid; Nesina. Product Category: Steroidal Compounds. Appearance: white powder. CAS No. 850649-62-6. Molecular formula: C25H27N5O4. Mole weight: 461.52. Purity: 95%+. IUPACName: 2-[[6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxopyrimidin-1-yl]methyl]benzonitrile;benzoicacid. Canonical SMILES: CN1C(=O)C=C(N(C1=O)CC2=CC=CC=C2C#N)N3CCCC(C3)N.C1=CC=C(C=C1)C(=O)O. Product ID: ACM850649626. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Alogliptin | Alogliptin is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibiting greater than 10000-fold selectivity over DPP-8 and DPP-9. Alogliptin is used for the prevention of type 2 diabetes. Uses: Hypoglycemic agents. Synonyms: (R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitril. Grade:>98%. CAS No. 850649-61-5. Molecular formula: C18H21N5O2. Mole weight: 339.39. | |
| Alogliptin | Alogliptin is an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Group: Biochemicals. Alternative Names: 2- [ [6- [ (3R) -3-Amino-1-piperidinyl] -3, 4-dihydro-3-methyl-2, 4-dioxo-1 (2H) -pyrimidinyl] methyl] benzonitrile. Grades: Highly Purified. CAS No. 850649-61-5. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Alogliptin-[13C,d3] | Alogliptin-[13C,d3] is the labelled analogue of Alogliptin. Alogliptin is an antidiabetic drug used for the treatment of type 2 diabetes and a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Synonyms: Alogliptin-13C,D3; 2-[[6-[(3R)-3-Amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]benzonitrile-13C,d3. Grade: >95%. CAS No. 1246817-18-4. Molecular formula: C17[13C]H18D3N5O2. Mole weight: 343.40. | |
| Alogliptin benzoate | Alogliptin benzoate(SYR 322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9. Uses: Dipeptidyl-peptidase iv inhibitors. Synonyms: 2-[[6-[(3R)-3-Amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]benzonitrile benzoate. Grade: 0.99. CAS No. 850649-62-6. Molecular formula: C25H27N5O4. Mole weight: 461.522. | |
| Alogliptin benzoate | Alogliptin benzoate. Group: Biochemicals. Grades: Highly Purified. CAS No. 850649-62-6. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C18H21N5O2C7H6O2. US Biological Life Sciences. | Worldwide |
| Alogliptin Benzoate | Alogliptin Benzoate (SYR-322) is a potent, selective and orally active inhibitor of DPP-4 with an IC 50 of <10 nM, and exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9. Alogliptin Benzoate can be used for the research of type 2 diabetes [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SYR 322. CAS No. 850649-62-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0023. | |
| Alogliptin Benzoate | Alogliptin Benzoate is the benzoate salt form of alogliptin, a selective, orally bioavailable, pyrimidinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. In addition to its effect on glucose levels, alogliptin may inhibit inflammatory responses by preventing the toll-like receptor 4 (TLR-4)-mediated formation of proinflammatory cytokines. Alternative Names: Nesina;SYR-322. CAS No. 850649-62-6. Product ID: API850649626. Molecular formula: C25H27N5O4. Mole weight: 461.5. EINECS: 691-730-4. SMILES: CN1C(=O)C=C(N(C1=O)CC2=CC=CC=C2C#N)N3CCC[C@H](C3)N.C1=CC=C(C=C1)C(=O)O. Standard: Facility GMP. Category: Hypoglycemic APIs. |  |
| Alogliptin-d3 | Labeled Alogliptin. It is an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Antidiabetic agent. Group: Biochemicals. Alternative Names: 2- [ [6- [ (3R) -3-Amino-1-piperidinyl] -3, 4-dihydro-3- (methyl-d3) -2, 4-dioxo-1 (2H) -pyrimidinyl] methyl] benzonitrile. Grades: Highly Purified. CAS No. 1133421-35-8. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Alogliptin-[d3] | Alogliptin-[d3] is the labelled analogue of Alogliptin. Alogliptin is an antidiabetic drug used for the treatment of type 2 diabetes and a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Synonyms: Alogliptin D3; 2-[[6-[(3R)-3-Amino-1-piperidinyl]-3,4-dihydro-3-(methyl-d3)-2,4-dioxo-1(2H)-pyrimidinyl]methyl]benzonitrile; Alogliptin-d3. Grade: ≥97% by HPLC; ≥99% atom D. CAS No. 1133421-35-8. Molecular formula: C18H18D3N5O2. Mole weight: 343.41. | |
| Alogliptin Hydroxy Impurity | Alogliptin Hydroxy Impurity is an impurity of alogliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor in the class of oral antidiabetic drugs. Molecular formula: C18H20N4O3. Mole weight: 340.38. | |
| Alogliptin Impurity 18 | Alogliptin Impurity 18. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-chloropyrimidine-2,4-diol. CAS No. 107577-09-3. Molecular formula: C4H3ClN2O2. Mole weight: 146.53. Catalog: APB107577093. |  |
| Alogliptin Impurity 28 | Alogliptin Impurity 28. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((3-methyl-2,4,6-trioxotetrahydropyrimidin-1(2H)-yl)methyl)benzonitrile. CAS No. 1246610-72-9. Molecular formula: C13H11N3O3. Mole weight: 257.24. Catalog: APB1246610729. | |
| Alogliptin Impurity 30 | Alogliptin Impurity 30. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-tert-butyl (1-(3-(2-cyanobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidin-3-yl)carbamate. CAS No. 1246610-74-1. Molecular formula: C23H29N5O4. Mole weight: 439.51. Catalog: APB1246610741. | |
| Alogliptin Related Compound 15 | A metabolite of Aloesin. Synonyms: Alogliptin Impurity C. Grade: > 95%. CAS No. 1108731-49-2. Molecular formula: C20H23N5O3. Mole weight: 381.44. | |
| Alogliptin Related Compound 18 | A metabolite of Aloesin. Grade: > 95%. CAS No. 1430222-09-5. Molecular formula: C26H23N5O4. Mole weight: 469.5. | |
| Alogliptin Related Compound 22 | A metabolite of Aloesin. Synonyms: 2-Dibromomethyl-benzonitrile. Grade: > 95%. CAS No. 655-63-0. Molecular formula: C8H5Br2N. Mole weight: 274.94. | |
| Alogliptin Related Compound 23 | A metabolite of Aloesin. Synonyms: N,N'-Bis(2'-cyanobenzyl)-6-chloro-2,4-dioxopyrimidine. Grade: > 95%. CAS No. 1618644-29-3. Molecular formula: C20H13ClN4O2. Mole weight: 376.81. | |
| Alogliptin Related Compound 24 | A metabolite of Aloesin. Synonyms: 2-[(6-Chloro-3-ethyl-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)methyl]-benzonitrile. Grade: > 95%. CAS No. 1430222-06-2. Molecular formula: C14H12ClN3O2. Mole weight: 289.72. | |
| Alogliptin Related Compound 25 | Alogliptin Related Compound 25 is an impurity of alogliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor in the class of oral antidiabetic drugs. Synonyms: Alogliptin-1-oxo-1-de(piperidin-3-amine). Grade: 95%. CAS No. 1246610-72-9. Molecular formula: C13H11N3O3. Mole weight: 257.25. | |
| Alogliptin Related Compound 26 | A metabolite of Aloesin. Synonyms: N-Desmethyl,N-2(2-cyanobenzyl) Alogliptin. Grade: > 95%. CAS No. 865759-10-0. Molecular formula: C25H24N6O2. Mole weight: 440.51. | |
| Alogliptin Related Compound 27 | A metabolite of Aloesin. Synonyms: 2-((6-Chloro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)methyl)benzonitrile. Grade: > 95%. CAS No. 865758-95-8. Molecular formula: C12H8ClN3O2. Mole weight: 261.67. | |
| Alogliptin Related Compound 29 | A metabolite of Aloesin. Synonyms: Loxoprofen acid. Grade: > 95%. CAS No. 1246610-74-1. Molecular formula: C23H29N5O4. Mole weight: 439.52. | |
| Alogliptin Related Compound 4 | A metabolite of Aloesin. Synonyms: 6-Despiperidinyl-6-(alogliptin-Namino-yl) Alogliptin. Grade: > 95%. CAS No. 1268836-55-0. Molecular formula: C31H30N8O4. Mole weight: 578.64. | |
| Alogliptin Related Compound 5 | A metabolite of Aloesin. Synonyms: Alogliptin Related Compound 5 (Racemic). Grade: > 95%. CAS No. 1338677-76-1. Molecular formula: C10H16N4O2. Mole weight: 224.26. | |
| Aloin | analytical standard. Group: Herbal medicinal products standards. | |
| Aloin | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardsimpurity standardspharmaceutical toxicology. | |
| Aloin A | Aloin A. Group: Biochemicals. CAS No. 1415-73-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Aloin-A | Aloin (Aloin-A; Barbaloin-A) is a natural anti-tumor anthraquinone glycoside with iron chelating activity. Aloin induces the differentiation of MC3T3-E1 cells into osteoblasts through MAPK-mediated Wnt and Bmp signaling pathways. Alkaline phosphatase (ALP) is an early marker of osteoblast differentiation, and the activity of ALP is also enhanced by Aloin. Aloin also reduces brain edema, reduces blood-brain barrier disruption and improves cortical impact injuries. Aloin is used in research into osteoporosis and traumatic brain injury (TBI) [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Barbaloin-A. CAS No. 1415-73-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N0123. | |
| Aloin A (Barbaloin A) | Aloin A (Barbaloin A). Group: Biochemicals. Alternative Names: Barbaloin A. Grades: Plant Grade. CAS No. 1415-73-2. Pack Sizes: 20mg. Molecular Formula: C21H22O9, Molecular Weight: 418.394. US Biological Life Sciences. | Worldwide |
| Aloin B | Aloin B. Group: Biochemicals. CAS No. 28371-16-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Aloin B (Isobarbaloin) | Aloin B (Isobarbaloin). Group: Biochemicals. Alternative Names: Isobarbaloin; β-Barbaloin. Grades: Plant Grade. CAS No. 28371-16-6. Pack Sizes: 20mg. Molecular Formula: C21H22O9, Molecular Weight: 418.398. US Biological Life Sciences. | Worldwide |
| Aloin (mixture of A&B) | Botanical Source: Group: Biochemicals. Alternative Names: Barbaloin, Socaloin, Ugandaloin, Jafaloin, Cafaloin. Grades: Plant Grade. CAS No. 8015-61-0. Pack Sizes: 20mg. US Biological Life Sciences. | Worldwide |
| Aloin Peracetate | Aloin Peracetate. Group: Biochemicals. Alternative Names: (S)-1,5-Anhydro-1-C-[4,5,10-tris(acetyloxy)-2-[(acetyloxy)methyl]-9-anthracenyl]-D-glucitol Tetracetate. Grades: Highly Purified. CAS No. 64951-96-8. Pack Sizes: 50mg. Molecular Formula: C37H38O17, Molecular Weight: 754.69. US Biological Life Sciences. | Worldwide |
| Aloisine A | Aloisine a is a cell-permeable pyrrolo-pyrazine compound that acts as a potent, selective, reversible, and ATP-competitive inhibitor of cyclin dependent kinases (Cdks: IC50 =150nM, 120 nM, 400 nM and 200 nM for Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, and Cdk5/p25, respectively). Uses: A potent and selective cdk and gsk-3 inhibitor. Synonyms: Aloisine A; 4-(7-Butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl)phenol. Grade: ≥98%. CAS No. 496864-16-5. Molecular formula: C16H17N3O. Mole weight: 267.33. | |
| Aloisine A - CAS 496864-16-5 | A cell-permeable pyrrolo-pyrazine compound that exerts anti-proliferative effects. Group: Fluorescence/luminescence spectroscopy. | |
| Aloisine A RP107 | Aloisine A RP107. Group: Biochemicals. Alternative Names: RP107, 7-n-Butyl-6-(4-hydroxyphenyl)-[5H]pyrrolo[2,3-b]pyrazine; 4-(7-Butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl)phenol. Grades: Highly Purified. CAS No. 496864-16-5. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C16H17N3O. US Biological Life Sciences. | Worldwide |
| Aloisine B | Aloisine B is a potent and selective CDK and GSK-3 inhibitor with highest affinity targets: Glycogen Synthase Kinase-3, Beta (Rattus norvegicus (rat)) (IC50=750.0 nM). Uses: A potent and selective cdk and gsk-3 inhibitor. Synonyms: 6-(4-chlorophenyl)-7-(propan-2-yl)-5H-pyrrolo[2,3-b]pyrazine; 6-phenyl[5H]pyrrolo[2,3-b]pyrazine (aloisine) 37; 6-(4-chlorophenyl)-7-isopropyl-5H-pyrrolo[2,3-b]pyrazine. Grade: ≥98%. CAS No. 496864-14-3. Molecular formula: C15H14ClN3. Mole weight: 271.75. | |
| Aloisine RP106 | Aloisine RP106. Group: Biochemicals. Alternative Names: RP106, 7-n-Butyl-6-(4-methoxyphenyl)-[5H]pyrrolo[2,3-b]pyrazine. Grades: Highly Purified. CAS No. 496864-15-4. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C17H19N3O. US Biological Life Sciences. | Worldwide |
| Aloisine RP106 | A cell-permeable pyrrolo-pyrazine compound that acts as a potent, selective, reversible, and ATP-competitive inhibitor of Cdk1/cyclin B, Cdk5/p35, and GSK-3 (IC50 = 700nM, 1.5 uM, and 920 nM, respectively). It is a derivative of the aloisines A and B, which competitively inhibit ATP binding to the catalytic subunit of CDKs and GSKs. Synonyms: RP106; 7-n-Butyl-6-(4-methoxyphenyl)-[5H]pyrrolo[2,3-b]pyrazine. Grade: ≥98%. CAS No. 496864-15-4. Molecular formula: C17H19N3O. Mole weight: 281.4. | |
| Aloperine | Botanical Source: Group: Biochemicals. Grades: Plant Grade. CAS No. 56293-29-9. Pack Sizes: 20mg. US Biological Life Sciences. | Worldwide |
| Aloperine | Aloperine is an alkaloid in sophora plants such as Sophora alopecuroides L, which has shown anti-cancer, anti-inflammatory and anti-virus properties [1]. Aloperine is widely used to treat patients with allergic contact dermatitis eczema and other skin inflammation in China [2]. Aloperine induces apoptosis and autophagy in HL-60 cells [1]. Uses: Scientific research. Group: Natural products. CAS No. 56293-29-9. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-13516. | |
| Aloperine | Aloperine is an alkaloid in sophora plants such as Sophora alopecuroides L, which has shown anti-cancer, anti-inflammatory and anti-virus properties.Aloperine is widely used to treat patients with allergic contact dermatitis eczema and other skin inflammation in China. Aloperine induces apoptosis and autophagy in HL-60 cells. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 6-Epi-aloperine. Product Category: Inhibitors. Appearance: Solid. CAS No. 56293-29-9. Molecular formula: C15H24N2. Mole weight: 232.36. Purity: 98%+. Canonical SMILES: [H][C@]1(C2)[C@](CCCC3)([H])N3C[C@]2([H])[C@@]4([H])C(CCCN4)=C1. Product ID: ACM56293299. Alfa Chemistry ISO 9001:2015 Certified. | |
| Alosetron | 25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C17H18N4O ·HCl. CAS No. 122852-42-0. Prepack ID 85312341-25mg. Molecular Weight 330.81. See USA prepack pricing. |  |
| Alosetron | Alosetron, an effective 5-HT3 receptor antagonist, could be commonly used against irritable bowel syndrome. Uses: Alosetron is an effective 5-ht3 receptor antagonist and could be commonly used against irritable bowel syndrome. Synonyms: Alosetron, GR 68755, GR68755, GR-68755, Lotronex; ALOSETRON2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one. Grade: 95%. CAS No. 122852-42-0. Molecular formula: C17H18N4O. Mole weight: 294.36. | |
| Alosetron-[d3] | Alosetron-[d3] is the labelled analogue of Alosetron, which is a 5-HT3 receptor antagonist used in the treatment of irritable bowel syndrome (IBS). Synonyms: Alosetron D3; 2,3,4,5-Tetrahydro-5-(methyl-d3)-2-[(4-methyl-1H-imidazol-5-yl)methyl]-1H-pyrido[4,3-b]indol-1-one; Lotronex-d3; 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrido[4,3-b]indol-1-one-d3. Grade: 98% by HPLC. CAS No. 1190043-13-0. Molecular formula: C17H15D3N4O. Mole weight: 297.37. | |
| Alosetron-[d3] Hydrochloride | Alosetron-[d3] Hydrochloride is the labelled analogue of Alosetron Hydrochloride, which is a 5-HT3 receptor antagonist used in the treatment of irritable bowel syndrome (IBS). Uses: The hydrochloride salt form of isotope labelled alosetrone. Synonyms: Alosetron-d3 Hydrochloride; 2,3,4,5-Tetrahydro-5-(methyl-d3)-2-[(4-methyl-1H-imidazol-5-yl)methyl]-1H-pyrido[4,3-b]indol-1-one Hydrochloride; GR 68755-d3; GR 68755X-d3; Lotronex-d3 Hydrochloride. Grade: >95%. CAS No. 1189919-71-8. Molecular formula: C17H15D3N4O.HCl. Mole weight: 333.83. | |
| Alosetron HCl | The hydrochloride salt form of Alosetron which is an effective 5-HT3 receptor antagonist and could be commonly used against irritable bowel syndrome. Uses: The hydrochloride salt form of alosetron which is an effective 5-ht3 receptor antagonist and could be commonly used against irritable bowel syndrome. Synonyms: 2,3,4,5-Tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-1H-pyrido[4,3-b]indol-1-one Hydrochloride. Grade: > 95%. CAS No. 122852-69-1. Molecular formula: C17H18N4O. HCl. Mole weight: 330.81. | |
| Alosetron hydrochloride | Alosetron hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Alosetron hydrochloride. Product Category: Heterocyclic Organic Compound. Appearance: Crystalline Solid. CAS No. 122852-69-1. Molecular formula: C17H19ClN4O. Mole weight: 330.81. Purity: 0.98. Density: 1.34g/cm³. Product ID: ACM122852691. Alfa Chemistry ISO 9001:2015 Certified. | |
| Alosetron Hydrochloride | Serotonin 5HT3-receptor antagonist. Used in treatment of irritable bowel syndrome. Group: Biochemicals. Alternative Names: 2,3,4,5-Tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-1H-pyrido[4,3-b]indol-1-one Hydrochloride; GR 68755; GR 68755X; Lotronex. Grades: Highly Purified. CAS No. 122852-69-1. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Alosetron Hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopyimpurity standardspharmaceutical toxicology. Alternative Names: Alosetron hydrochloride, 1H-Pyrido[4,3-b]indol-1-one, 2,3,4,5-tetrahydro-5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-, monohydrochloride (9CI), GR 68755C,2,3,4,5-Tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-1H-pyrido[4,3-b]indol-1-one Hydrochloride (1:1). | |
| Alosetron Hydrochloride | Alosetron Hydrochloride (GR 68755C) is a potent and highly selective serotonin 5-HT3 receptor antagonist. Alosetron Hydrochloride is used for the research of irritable bowel syndrome (IBS). Alosetron blocks the fast 5HT3-mediated depolarisation of guinea-pig myenteric and submucosal neurons, with IC 50 at ~55 nM. Alosetron Hydrochloride attenuates the visceral nociceptive effect of rectal distension in conscious or anaesthetised dogs. Anti-inflammatory effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GR 68755C; GR 68755 Hydrochloride; GR 68755X Hydrochloride. CAS No. 122852-69-1. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-70050C. | |
| Alosetron Hydrochloride | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Alosetron Hydrochloride(1:X) | The hydrochloride salt form of Alosetron, a 5HT3-receptor antagonist, could be used against bowel syndrome. Uses: The hydrochloride salt form of alosetron is a 5ht3-receptor antagonist that could be used against bowel syndrome. Synonyms: GR 68755; GR 68755X; Lotronex; GR-68755; GR68755. Grade: 95%. CAS No. 132414-02-9. Molecular formula: C17H19ClN4O. Mole weight: 330.81. | |
| Alosetron N-β-D-Glucuronide | A derivative of Alosetron. Synonyms: 1-Deoxy-1-[4-methyl-5-[(1,3,4,5-tetrahydro-5-methyl-1-oxo-2H-pyrido[4,3-b]indol-2-yl)methyl]-1H-imidazol-1-yl]-β-D-glucopyranuronic Acid. Grade: > 95%. CAS No. 863485-56-7. Molecular formula: C23H26N4O7. Mole weight: 470.49. | |
| Alosetron (Z)-2-butenedioate | The maleic acid salt form of Alosetron which is an effective 5-HT3 receptor antagonist and could be commonly used against irritable bowel syndrome. Uses: The maleic acid salt form of alosetron which is an effective 5-ht3 receptor antagonist and could be commonly used against irritable bowel syndrome. Synonyms: (Z)-but-2-enedioicacid; 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrido[4,3-b]indol-1-one; Alosetron((Z)-2-butenedioate); 122852-43-1; SCHEMBL1045; Alosetron(Z)-2-butenedioate. Grade: 95%. CAS No. 122852-43-1. Molecular formula: C21H22N4O5. Mole weight: 410.42. | |
| ALOX15 active human | recombinant, expressed in baculovirus infected Sf9 cells, ?60% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Aloxistatin | Aloxistatin is an inhibitor of cathepsins B and L as well as a potential inhibitor of calpain, which predicted to function against SARS-CoV-2 infection. Synonyms: L-trans-Epoxysuccinyl(OEt)-Leu-3-methylbutylamide; L-trans-Epoxysuccinyl-Leu-3-methylbutylamide-ethyl ester; (2S,3S)-3-[[[(1S)-3-Methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-2-oxiranecarboxylic Acid Ethyl Ester; E 64c ethyl ester; E 64d; EP 453; EST; Loxistatin; NSC 694281; (2S,3S)-trans-Epoxysuccinyl-L-leucylamido-3-methylbutane ethyl ester. Grade: 98%. CAS No. 88321-09-9. Molecular formula: C17H30N2O5. Mole weight: 342.43. | |
| Aloxistatin | Aloxistatin (E64d) is a cell-permeable and irreversible broad-spectrum cysteine protease inhibitor. Aloxistatin (E64d) exhibits entry-blocking effect for MERS-CoV. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E64d; E64c ethyl ester. CAS No. 88321-09-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100229. | |
| Aloxistatin (E-64d) | Aloxistatin (E-64d), is a selective cysteine protease inhibitor or calpain and autophagy inhibitor. E-64d prevents in vitro cerulein- induced trypsinogen activation. E-64d can enter the intact cell and inhibit calpain. E-64d has been shown safe for the treatment of Alzheimer's disease in human. E-64d is potentially useful in the treatment of developmental seizure-induced brain damage both by regulating abnormal zinc signal transduction and through the modulation of altered lipid metabolism via ApoE/clusterin pathway in hippocampus. Uses: Designed for use in research and industrial production. Additional or Alternative Names: E-64d; E 64d; E64d; E64-d; E64-d; E64 d; ethyl ester Loxistatin; NSC 694281; NSC694281; NSC-694281; EST; EP-453; EP453; EP 453; Aloxistatin. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 88321-09-9. Molecular formula: C17H30N2O5. Mole weight: 342.44. Purity: >98%. IUPACName: ethyl (2S,3S)-3-(((S)-1-(isopentylamino)-4-methyl-1-oxopentan-2-yl)carbamoyl)oxirane-2-carboxylate. Canonical SMILES: CCOC([C@@H]1[C@@H](C(N[C@H](C(NCCC(C)C)=O)CC(C)C)=O)O1)=O. Product ID: ACM88321099. Alfa Chemistry ISO 9001:2015 Certified. | |
| AlPCCI | AlPCCI. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 31h-phthalocyaninato(2-)-n29,n39,n31,n32]-chloro[29(sp-5-12)-aluminu;chloro[29H,31H-phthalocyaninato(2-)-N29,N30,N31,N32]-,(SP-5-12)-Aluminum;CHLOROALUMINUM PHTHALOCYANINE;CHLORO(29H,31H-PHTHALOCYANINATO)ALUMINUM;CHLORO(PHTHALOCYANINATO)ALUMINIUM;ALUMINUM. Product Category: Photonic and Optical Device. CAS No. 14154-42-8. Molecular formula: C32H16AlClN8. Mole weight: 574.96. Product ID: ACM14154428. Alfa Chemistry ISO 9001:2015 Certified. Categories: AlSPc, Alpecin-Deceuninck. | |
| Alpelisib | Alpelisib Inhibitor. Uses: Scientific use. Product Category: T1921. CAS No. 1217486-61-7. |  |
| Alpelisib | Alpelisib, also known as BLY719, is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor BYL719 specifically inhibits PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling pathway, thereby inhibiting the activation of the PI3K signaling pathway. This may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations. Activation of the PI3K signaling pathway is frequently associated with tumorigenesis. Dysregulated PI3K signaling may contribute to tumor resistance to a variety of antineoplastic agents. Synonyms: BYL-719; BYL719; BYL 719; Alpelisib. CAS No. 1217486-61-7. Molecular formula: C19H22F3N5O2S. Mole weight: 441.473. | |
| Alpelisib | Alpelisib (BYL-719) is a potent, selective, and orally active PI3Kα inhibitor. Alpelisib (BYL-719) shows efficacy in targeting PIK3CA-mutated cancer. Alpelisib (BYL-719) also inhibits p110α /p110γ /p110δ /p110β with IC 50 s of 5/250/290/1200 nM, respectively. Antineoplastic activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BYL-719. CAS No. 1217486-61-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-15244. | |
| Alpelisib, Free Base, 99+% | Alpelisib, also known as BYL719, is a potent and selective phosphatidylinositol-3 kinase [alpha] inhibitor. It inhibited P110[alpha], p110[beta], p110[delta], and p110[gamma] with IC50 values of 5 nM, 1.2 µM, 0.29 µM and 0.25 µM, respectively, in biochemical assays. It inhibited the Akt phosphorylation with IC50 values of 74 nM in Rat1-myr-p110[alpha] cells, 2.2 µM in Rat1-myr-p110[beta] cells, and 1.2 µM in Rat1-myr-p110[delta] cells. Furet P., et al. "Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation." Bioorg. Med. Chem. Lett. 23: 3741-3748 (2013). Group: Biochemicals. Alternative Names: BYL-719; NVP-BYL719; (S)-Pyrrolidine-1,2-dicarboxylic Acid 2-Amide 1-[4-Methyl-5-[2-(2,2,2-trifluoro-1,1-dimethylethyl)-pyridin-4-yl]thiazol-2-yl]amide; (2S) -N1- [4- methyl -5- [2- (2, 2, 2-tri fluoro -1, 1-di methyl ethyl ) -4-pyridinyl ] -2-thiazoly l ] -1, 2-pyrrolidinedicarboxami de . Grades: Highly Purified. CAS No. 1217486-61-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C19H22F3N5O2S, Molecular Weight: 441.47. US Biological Life Sciences. | Worldwide |
| Alpelisib hydrochloride | Alpelisib hydrochloride shows antineoplastic activity. Alpelisib hydrochloride is a potent, orally active, and selective PI3Kα inhibitor with IC50s of 5 nM, 250 nM, 290 nM and 1200 nM for p110α, p110γ, p110δ, and p110β, respectively. Synonyms: BYL-719 hydrochloride. CAS No. 1584128-91-5. Molecular formula: C19H23ClF3N5O2S. Mole weight: 477.93. | |
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