A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
alseroxylon. Uses: Designed for use in research and industrial production. Additional or Alternative Names: alseroxylon. Product Category: Heterocyclic Organic Compound. CAS No. 8001-95-4. Mole weight: 281.8259. Density: g/cm³. Product ID: ACM8001954. Alfa Chemistry ISO 9001:2015 Certified.
Alsevalimab
Alsevalimab is a human monoclonal antibody that targets B7-H4 with potential antineoplastic and immune checkpoint inhibitory activities. CAS No. 2254029-91-7.
Alsevalimab
Alsevalimab is a human monoclonal antibody against B7-H4 [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2254029-91-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99242.
ALS-I
ALS-I, an acid-Liable surfactant, is adopted for in-solution enzymatic digestions, can help to solubilize hydrophobic proteins. ALS-I is significantly enhanced peptide recovery for mass spectrometry (MS) mapping in the study of the proteomes of regenerating rat retina and mouse brain [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 308818-13-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-44157.
Also Nameel F46 Tubing
Also Nameel F46 Tubing. Group: Polymers.
Alsterpaullone
Potent CDK1/cyclin B (IC50 = 35 nM) inhibitor. Anti-tumor compound Potent inhibitor of CDK2/cyclin A, CDK2/cyclin E (IC50 = 200 nM), CDK5/p25 (IC50 = 40 nM), CDK5/p35 (IC50 = 40 nM). GSK-3beta (glycogen synthase kinase-3beta) inhibitor. Apoptosis inhibitor. Apoptosis inducer. Angiogenesis inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 237430-03-4. Pack Sizes: 1mg, 5mg. Molecular Formula: C16H11N3O3. US Biological Life Sciences.
Worldwide
Alsterpaullone
Alsterpaullone is a potent glycogen synthase kinase-3 inhibitor and a potential therapeutic agent for the treatment of Parkinson disease. Alsterpaullone is also known as 9-Nitropaullone and NSC 705701, which is a derivative of kenpaullone and an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) and glycogen synthase kinase 3β (GSK3β). Alsterpaullone induces apoptosis by activation of caspase-9 due to perturbation in mitochondrial membrane potential. Alsterpaullone is a derivative of kenpaullone with slightly improved potency over kenpaullone, alsterpaullone selectively inhibits Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p25, and GSK3α/β with IC50 values of 35, 15, 200, 40, and 4 nM, respectively. Synonyms: 9-Nitropaullone; NSC 705701; 7,12-Dihydro-9-nitro-indolo[3,2-d][1]benzazepin-6(5H)-one. Grades: ≥98%. CAS No. 237430-03-4. Molecular formula: C16H11N3O3. Mole weight: 293.3.
Alsterpaullone
Alsterpaullone (9-Nitropaullone) is a potent CDK inhibitor, with IC50s of 35 nM, 15 nM, 200 nM and 40 nM for CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E and CDK5/p35, respectively. Alsterpaullone also competes with ATP for binding to GSK-3alpha/GSK-3beta with IC50s of both 4 nM. Alsterpaullone has antitumor activity, and possesses potential for the study in neurodegenerative and proliferative disorders. Alsterpaullone induces apoptosis in leukemia cell line. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 237430-03-4. Molecular formula: C16H11N3O3. Mole weight: 293.28. Purity: >95%. Product ID: ACM237430034. Alfa Chemistry ISO 9001:2015 Certified.
A cell-permeable and reversible Alsterpaullone derivative that acts as a highly potent, ATP-competitive, selective inhibitor of Cdk1/cyclin B and GSK-3?. Group: Fluorescence/luminescence spectroscopy.
Alsterpaullone - CAS 237430-03-4
A cell-permeable, potent, reversible, and ATP competitive inhibitor of GSK-3? (IC?? = 4 nM) and Cdk1/cyclin B (IC?? = 35 nM). Group: Fluorescence/luminescence spectroscopy.
Alstonine
Cas No. 642-18-2.
Altanserin
Altanserin can synthesize Fluorine-18 Altanserin. Fluorine-18 Altanserin binds to the brain 5HT 2 receptors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 76330-71-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119156.
Altanserin hydrochloride
Altanserin hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1135280-78-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Altanserin hydrochloride
Altanserin hydrochloride is the hydrochloride salt of altanserin, which is a selective and potent 5-HT2A receptor antagonist with Ki value of 0.13 nM. It is centrally active following systemic administration in vivo. It is also a useful intermediate for organic synthesis. Synonyms: 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone hydrochloride. Grades: ≥98% by HPLC. CAS No. 1135280-78-2. Molecular formula: C22H23FN3O2SCl. Mole weight: 447.95.
Altechromone A is produced from Alternaria brassicicola ML-P08. Altechromone A shows antimicrobial activity against Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens and Candida albicans with the MICs of 3.9, 3.9, 1.8, and 3.9 ug/ml, respectively. Synonyms: 7-Hydroxy-2,5-dimethylchromone; 7-Hydroxy-2,5-dimethyl-4H-1-benzopyran-4-one. Grades: 98.0%. CAS No. 38412-47-4. Molecular formula: C11H10O3. Mole weight: 190.19.
Alteichin
It is produced by the strain of Alternaria eichorniae. Phytotoxic substances. Synonyms: alterperylenol; Alteichin; GRK18WHV7F; C10295; (+)-Alterperylenol; AC1L2PAW; Alterperylnol; CHEBI:2614; DTXSID10237401; ZINC4098645; AKOS030213167; (1S,12aR,12bS)-1,4,9,12a-tetrahydroxy-2,12b-dihydro-1H-perylene-3,10-dione; Q27105736; 3,10-Perylenedione,1,2,12a,12b-tetrahydro-1,4,9,12a-tetrahydroxy-, (1S,12aR,12bS)-; 3,10-Perylenedione, 1,2,12a,12b-tetrahydro-1,4,9,12a-tetrahydroxy-, (1alpha,12abeta,12balpha)-(+)-. Grades: 95%. CAS No. 88899-62-1. Molecular formula: C20H14O6. Mole weight: 350.32.
Altemicidin
It is produced by the strain of Streptomyces sioyaensis. It has acaricidal and anti-tumor activity. The inhibition IC50 of L1210 and IMC cancer cells was 0.84 and 0.82 ?/mL. Synonyms: CTK4B4358; DTXSID20925120; 1H-Cyclopenta[c]pyridine-7-carboxylicacid,4-(aminocarbonyl)-7-[[2-(aminosulfonyl)acetyl]amino]-2,4a,5,6,7,7a-hexahydro-6-hydroxy-2-methyl-,(4aR,6S,7R,7aS)-; LS-136376; Q15410226; 6-Hydroxy-7- ({[ (1-hydroxy-2-sulfamoylethylidene) amino]oxy}carbonyl) -2-methyl-2, 4a, 5, 6, 7, 7a-hexahydro-1H-cyclopenta[c]pyridine-4-carboximidic acid. Grades: 99%. CAS No. 125399-82-8. Molecular formula: C13H20N4O7S. Mole weight: 376.38.
ALTEMPO
[4-N-(4-amino-2,2,6,6-tetramethylpiperidine-1-oxyl)] algin amine. Product ID: 8-05068. Properties: water soluble dextran.
Altenuene
Altenuene is a heptaketide isolated from an endolichenic fungal strain Nigrospora sphaerica [1]. Uses: Scientific research. Group: Natural products. CAS No. 29752-43-0. Pack Sizes: 1 mg. Product ID: HY-N6713A.
Altenuene
(-)-Altenuene is a toxin isolated from the fungus Alternaria tenuis. It has antioxidant activity and inhibits cholinesterases. Synonyms: (2R,3R,4aR)-2,3,4,4a-Tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-6H-dibenzo[b,d]pyran-6-one. Grades: >95%. CAS No. 29752-43-0. Molecular formula: C15H16O6. Mole weight: 292.29.
Altenusin
Altenusin is a a biphenyl derivative with an IC50 value of 4.3±0.3 μM in the TR assay, which is isolated from the endophytic fungus Alternaria. It inhibits Src kinase with an IC50 value of 20 nM. Altenusin inhibits fibrillization of recombinant tau fragments in vitro and phosphorylation of tau in SH-SY5Y cells expressing human P301L mutant tau when used at a concentration of 10 μM. Altenusin is known to have antioxidant properties and to inhibit several enzymes, including myosin light chain kinase, sphingomyelinase, acetylcholinesterase, cFMS kinase, pp60c-SRc kinase and HIV-1 integrase. Synonyms: Alutenusin; MS 341; MS-341; MS341. Grades: ≥98%. CAS No. 31186-12-6. Molecular formula: C15H14O6. Mole weight: 290.27.
Sphingomyelinase (N-SMase) and strong pp60c-Src inhibitor. Inhibits cFMS receptor tyrosine kinase (CSF-1/m-CSF receptor tyrosine kinase) which is implicated in cancer and bone diseases. Myosin light chain kinase inhibitor. Also exhibits anti-HIV-1 integrase activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 31186-12-6. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
Worldwide
Alteplase
Alteplase (Actilyse; Activase), a tissue plasminogen activator prepared by recombination, is a thrombolytic agent that play important roles in acute ischemic stroke, pulmonary embolism, acute myocardial infarction, and occluded catheters [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Actilyse; Activase. CAS No. 105857-23-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108865.
Alterlactone
Alterlactone is produced from the endolichenic fungus Ulocladium sp. Alterlactone shows strong radical scavenging activity. Synonyms: 4,9,10-trihydroxy-2-methoxydibenzo[c,e]oxepin-5(7H)-one. Grades: 97.5%. CAS No. 1030376-89-6. Molecular formula: C15H12O6. Mole weight: 288.25.
alternansucrase
The product, which has quite different properties from other dextrans, has been called alternan. Group: Enzymes. Synonyms: sucrose-1,6(3)-α-glucan 6(3)-α-glucosyltransferase; sucrose:1,6-, 1,3-α-D-glucan 3-α- and 6-α-D-glucosyltransferase;sucrose:1,6(1,3)-α-D-glucan 6(3)-α-D-glucosyltransferase. Enzyme Commission Number: EC 2.4.1.140. CAS No. 100630-46-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2366; alternansucrase; EC 2.4.1.140; 100630-46-4; sucrose-1,6(3)-α-glucan 6(3)-α-glucosyltransferase; sucrose:1,6-, 1,3-α-D-glucan 3-α- and 6-α-D-glucosyltransferase;sucrose:1,6(1,3)-α-D-glucan 6(3)-α-D-glucosyltransferase. Cat No: EXWM-2366.
Alternapyrone
Alternapyrone is a polyketide produced in A. oryzae heterologously expressing the A. solani-derived polyketide synthase gene alt5. CAS No. 676340-02-6. Molecular formula: C28H44O3. Mole weight: 428.65.
Alternapyrone B
Cas No. 2254311-61-8. Molecular formula: C28H42O5. Mole weight: 458.63.
Alternaric acid
It is produced by the strain of Alternaria solani. The main antifungal activity was 0.1-1.0 ?/mL, which inhibited the spore germination of Plomonas aeruginosa, Porphyra porphyra and Black grapevine panicle. Synonyms: D-Arabinonic acid,4,5-dideoxy-2-C-((1E)-7-((6R)-5,6-dihydro-4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-4-methylene-7-oxo-1-heptenyl)-4-ethyl; 3-Nonenoic acid,9-(5,6-dihydro-4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-2-hydroxy-2-(1-hydroxy-2-methylbutyl)-6-methylene-9-oxo-,(6R-(3(2S*(1R*,2S*),3E),6R*)); 3-Octenoic acid,2-hydroxy-2-(1-hydroxy-2-methylbutyl)-6-methylene-8-[(tetrahydro-6-methyl-2,4-dioxopyran-3-yl)carbonyl]-(8CI); Alternaric acid (6CI,7CI); D-Arabinonic acid,4,5-dideoxy-2-C-[(1E)-7-[(6R)-5,6-dihydro-4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl]-4-methylene-7-oxo-1-heptenyl]-4-ethyl-(9CI). Grades: 98%. CAS No. 10088-62-7. Molecular formula: C21H30O8. Mole weight: 410.46.
Alternariol
Alternariol is an orally ingested mycotoxin produced by Alternaria , capable of inhibiting the activity of topoisomerase I and II ( topoisomerase I , topoisomerase II ). Alternariol has weak estrogenic ( Estrogen Receptor/ERR ) and androgen/antiandrogen ( Androgen Receptor ) effects. Alternariol can induce apoptosis , trigger cell cycle arrest, suppress innate immune responses, and exhibit anti-tumor activity. Alternariol has genotoxic, mutagenic, and endocrine-disrupting effects [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 641-38-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6714.
Alternariol
It is produced by the strain of Alternaria tenuis. The inhibition concentration of S. aureus and E. coli was 1:40000 and 1:20000, respectively. Synonyms: 3,7,9-Trihydroxy-1-methyl-6H-benzo[c]chromen-6-one; 3,7,9-trihydroxy-1-methylbenzo[c]chromen-6-one; 3,7,9-Trihydroxy-1-methyl-6H-dibenzo[b,d]pyran-6-one; CCRIS 6734; AOH; KN9L4260JW; CHEBI:64983; NSC638263; 3,4,4'-Trihydroxy-6'-methyl-2-biphenylcarboxylic acid, gamma lactone; 3,7,9-Trihydroxy-1-methyl-6H-dibenzo(b,d)pyran-6-one; CHEMBL519982. Grades: 97%. CAS No. 641-38-3. Molecular formula: C14H10O5. Mole weight: 258.23.
Alternariol
An alternaria mycotoxin and genotoxin, found in common edible crops. It inhibits the activity of various DNA-topoisomerases, increasing he rate of DNA strand breaks. Group: Biochemicals. Alternative Names: 3,7,9-Trihydroxy-1-methyl-6H-dibenzo[b,d]pyran-6-one; NSC 638263. Grades: Highly Purified. CAS No. 641-38-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Alternariol
Alternariol is a mycotoxin produced by Alternaria species. AOH inhibits the catalytic activity of topoisomerase I andtopoisomerase II enzymes. Alternariol exhibits a variety of therapeutic and biological properties such as phytotoxicity, cytotoxicity, anti-HIV, anti-cancer, and anti-microbial properties. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Powder. CAS No. 641-38-3. Molecular formula: C14H10O5. Mole weight: 258.22. Purity: 0.98. IUPACName: 3,7,9-trihydroxy-1-methylbenzo[c]chromen-6-one. Canonical SMILES: CC1=CC(=CC2=C1C3=CC(=CC(=C3C(=O)O2)O)O)O. Product ID: ACM641383-1. Alfa Chemistry ISO 9001:2015 Certified.
Alternariol 9-Methyl Ether 3-Sulfate Ammonium Salt
Alternariol 9-Methyl Ether 3-Sulfate Ammonium Salt is a derivative of Alternariol 9-Methyl Ether (A575770) which is an alternaria mycotoxin and genotoxin, found in common edible crops. It inhibits the activity of various DNA-topoisomerases, increasing he rate of DNA strand breaks. Group: Biochemicals. Grades: Highly Purified. CAS No. 1488351-25-2. Pack Sizes: 1mg. Molecular Formula: C15H12O8S(NH3), Molecular Weight: 352.321703. US Biological Life Sciences.
Worldwide
Alternariol 9-Monomethyl Ether
Alternariol Monomethyl Ether is a mycotoxins found in subsistence farmed maize. Also, it is a natural mycotoxin isolated from the fermentation broth of Trichoderma sp. Jing-8 with phytotoxic, antibacterial and antioxidant activities. Also, it is derived from 3,5-Dimethoxyiodobenzene (D460640), which is an intermediate for the synthesis of glucuronide conjugates of trans-Resveratrol. Group: Biochemicals. Grades: Highly Purified. CAS No. 23452-05-3. Pack Sizes: 5mg, 10mg. Molecular Formula: C15H12O5, Molecular Weight: 272.25. US Biological Life Sciences.
Alternariol, methyl ether is a common mycotoxin found in spoiled grains and is mutagenic and carcinogenic in vitro [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 26894-49-5. Pack Sizes: 100 μg. Product ID: HY-W585866.
Alternariol monomethyl ether
The 50 ppm acetonitrile solution of Alternariol monomethyl ether, shows activities as a cholinesterase inhibitor as well as an anti-fungal agent, could be commonly used as a standard solution. It is an alternaria mycotoxin and genotoxin, which can inhibit the activity of DNA-topoisomerases. Synonyms: 6H-Dibenzo[b,d]pyran-6-one, 3,7(3,9 or 7,9)-dihydroxy-9(7 or 3)-methoxy-1-methyl-; 3,7(3,9 or 7,9)-Dihydroxy-9(7 or 3)-methoxy-1-methyl-6H-dibenzo[b,d]pyran-6-one; Alternariol, methyl ether. Grades: >95%. CAS No. 26894-49-5. Molecular formula: C15H12O5. Mole weight: 272.25.
Alternariol Monomethyl Ether
An alternaria mycotoxin and genotoxin, found in common edible crops. It inhibits the activity of various DNA-topoisomerases, increasing he rate of DNA strand breaks. Group: Biochemicals. Alternative Names: 3,7(3,9 or 7,9)-Dihydroxy-9(7 or 3)-methoxy-1-methyl-6H-dibenzo[b,d]pyran-6-one. Grades: Highly Purified. CAS No. 26894-49-5. Pack Sizes: 1mg. US Biological Life Sciences.
Mycotoxin. Antifungal. Phytotoxic. Shown to possess DNA strand-breaking activity. Inhibits the activity of topoisomerase IIalpha (Topo IIalpha) in mammalian cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 26894-49-5. Pack Sizes: 500ug, 1mg, 5mg. US Biological Life Sciences.
Worldwide
alternative-complement-pathway C3/C5 convertase
A bimolecular complex of complement fragment Bb with either C3b or cobra venom factor; Bb contains the active site. Bb is formed by cleavage of proenzyme factor B by factor D. Cleavage of complement component C5 requires additional C3b which binds C5 and renders it susceptible to cleavage by C3b,Bb complex. C3b,Bb is stabilized in plasma by factor P. Complement factor B is in peptidase family S1 (trypsin family). Group: Enzymes. Synonyms: complement component C3/C5 convertase (alternative); proenzyme factor B; properdin factor B; C3 proactivator; glycine-rich β-glycoprotein; heat-labile factor; C3 convertase; C3. Enzyme Commission Number: EC 3.4.21.47. CAS No. 80295-67-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4140; alternative-complement-pathway C3/C5 convertase; EC 3.4.21.47; 80295-67-6; complement component C3/C5 convertase (alternative); proenzyme factor B; properdin factor B; C3 proactivator; glycine-rich β-glycoprotein; heat-labile factor; C3 convertase; C3b,Bb,CVF,Bb,C5 convertase; (C3b)n,Bb; complement C 3(C 5) convertase (amplification); alternative complement pathway C3(C5) convertase; C5 convertase; CVF,Bb; (CVF)-dependent glycine-rich-β-glucoprotein; cobra venom factor-dependent C3 convertase. Cat No: EXWM-4140.
Altertoxin I
Altertoxin I, a sort of natural mycotoxin, could be obtained from Alternaria fungi and has been found to restrain human topoisomerase II as well as bacterial gyrase. Altertoxin I (and other altertoxins) inhibit the HIV replication. Synonyms: Altertoxin-I; BC9625200. Grades: ≥97%. CAS No. 56258-32-3. Molecular formula: C20H16O6. Mole weight: 352.34.
Althiazide
Diuretic and antihypertensive. Group: Biochemicals. Alternative Names: 6-Chloro-3,4-dihydro-3-[(2-propen-1-ylthio)methyl]-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxide; 3-[(Allylthio)methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxide; Althizide; Altizid; Altizide. Grades: Highly Purified. CAS No. 5588-16-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Althiomycin
It is produced by the strain of Streptomyces althiotious. Anti-Gram-positive bacteria (weak) and E. coli (weak). Synonyms: Althiomycin; Altiomycin; NSC 102809; 4-Thiazolecarboxamide, N-(1-(4-((2,5-dihydro-4-methoxy-2-oxo-1H-pyrrol-1-yl)carbonyl)-4,5-dihydro-2-thiazolyl)-2-hydroxyethyl)-2-((hydroxyimino)methyl)-; NSC102809. CAS No. 12656-40-5. Molecular formula: C16H17N5O6S2. Mole weight: 439.47.
Altiloxin A
It is produced by the strain of Phoma asparagi Sacc ALD-8. It is a plant toxin that can inhibit the growth of roots. Synonyms: (1as,3s,4r,4ar,8ar)-3-hydroxy-3,4a,8,8-tetramethyloctahydro-1ah-naphtho[1,8a-b]oxirene-4-carboxylic acid; (-)-Altiloxin A; CTK5H1580; DTXSID20896902; 3H-Naphth(1,8a-b)oxirene-4-carboxylic acid, octahydro-3-hydroxy-3,4a,8,8-tetramethyl-, (1aS,3R,4R,4aR,8aR)-; 3H-Naphth(1,8a-b)oxirene-4-carboxylic acid, octahydro-3-hydroxy-3,4a,8,8-tetramethyl-, (1aS-(1aalpha,3beta,4alpha,4aalpha,8aS*))-. Grades: 95%. CAS No. 92675-11-1. Molecular formula: C15H24O4. Mole weight: 268.35.
Altiloxin B
It is produced by the strain of Phoma asparagi Sacc ALD-8. Plant toxin. Synonyms: (1aS,8aS)-7α-Chlorooctahydro-3β-hydroxy-3,4aα,8,8-tetramethyl-3H-naphth[1,8a-b]oxirene-4α-carboxylic acid. CAS No. 92675-14-4. Molecular formula: C15H23O4Cl. Mole weight: 302.79.
Altiratinib
Altiratinib, also known as DCC-270, DP-5164, is an oral, selective and highly potent inhibitor of MET, TIE2, VEGFR2 and TRK kinases with potential anticancer activity. DCC-2701 effectively reduces tumor burden in vivo and blocks c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with a HGF antagonist in vitro. Importantly, DCC-2701's anti-proliferative activity was dependent on c-MET activation induced by stromal human fibroblasts and to a lesser extent exogenous HGF. DCC-2701 may be superior to HGF antagonists that are in clinical trials and that pTyr(1349) levels might be a good indicator of c-MET activation and likely response to targeted therapy as a result of signals from the microenvironment. Synonyms: DCC2701; DCC 2701; DCC-2701; DP 5164; DP5164; DP-5164; Altiratinib. Grades: >98%. CAS No. 1345847-93-9. Molecular formula: C26H21F3N4O4. Mole weight: 510.46.
Altiratinib
Altiratinib. Group: Biochemicals. Grades: Highly Purified. CAS No. 1345847-93-9. Pack Sizes: 100mg. US Biological Life Sciences.
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AlTiVFeCr High-Entropy Alloy
Unlike most current alloy materials, high-entropy alloys are alloy materials that contain equimolar or approximately equimolar elements. AlTiVFeCr High-Entropy Alloy is composed of Al, Ti, V, and Fe. Uses: Military use, replace part of superalloy. Group: High entropy alloys. Pack Sizes: Our AlTiVFeCr High-Entropy Alloy is carefully handled during storage and transportation to preserve the quality of our product in its original condition.
Altogen Labs Biology CRO
Altogen Labs is a preclinical contract research organization (CRO) that provides a wide range of laboratory services to biotech and pharma companies. Services includes: Xenograft models (CDX and PDX), pharm/tox studies, PK/PD, and more. Uses: Preclinical research services: Validated xenograft models (CDX and PDX). Product ID: 9999.
Nevada, Texas, USA
Altrenogest
Altrenogest. Group: Biochemicals. Alternative Names: (17b)-17-Hydroxy-17-(2-propen-1-yl)estra-4,9,11-trien-3-one; (17b)-17-Hydroxy-17-(2-propenyl)estra-4,9,11-trien-3-one; 17a-Allyl-17-hydroxyestra-4,9,11-trien-3-one. Grades: Highly Purified. CAS No. 850-52-2. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C21H26O2. US Biological Life Sciences.
Worldwide
Altrenogest
Altrenogest is a progestogen structurally related to veterinary steroid trenbolone. It is a synthetic active progesterone. It can suppress the sow's estrus to achieve the purpose of estrus in the pig herd at the same time, reshape the sow's physiological cycle, and induce the sow to estrus at the same time. Uses: Progestins. Synonyms: Altrenogest; A 35957; A-35957; Allyl trenbolone; DRC 6246; R 2267; REGU-MATE; Regumate; RU 2267; RU-2267. Grades: >98%. CAS No. 850-52-2. Molecular formula: C21H26O2. Mole weight: 310.43.
Altrenogest
Altrenogest (Allyltrenbolone) is a progestogen structurally related to veterinary steroid trenbolone. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Allyltrenbolone; RU2267. CAS No. 850-52-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0521.
Altrenogest 19,19,20,21,21 (d5)
Altrenogest 19,19,20,21,21-d5 is labelled Altrenogest (A575755) which is a synthetic progestational agent used in veterinary medicine for the control of estrus in mares. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250ug, 500ug. Molecular Formula: C21H21D5O2. US Biological Life Sciences.
Worldwide
Altretamine
An antitumor agent which also acts as a chemosterilant for male houseflies and other insects. Antineoplastic. Group: Biochemicals. Alternative Names: N2,N2,N4,N4,N6,N6-Hexamethyl-1,3,5-triazine-2,4,6-triamine; 1,3,5-Tris(dimethylamino)-s-triazine; 2,4,6-Tris(dimethylamino)-1,3,5-triazine; ENT 50852; HMM; Hemel; Hexalen; Hexamethylmelamine; Hexylen; NSC 13875. Grades: Highly Purified. CAS No. 645-05-6. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences.
Worldwide
Altretamine
Altretamine is an anti-neoplastic agent. Uses: An antitumor agent which also acts as a chemosterilant for male houseflies and other insects. antineoplastic. Synonyms: 2-N,2-N,4-N,4-N,6-N,6-N-hexamethyl-1,3,5-triazine-2,4,6-triamine. Grades: > 98 %. CAS No. 645-05-6. Molecular formula: C9H18N6. Mole weight: 210.28.
Altretamine
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Altretamine
Altretamine is an alkylating antineoplastic agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ENT-50852; RB-1515; WR-95704. CAS No. 645-05-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0181.
Altretamine hydrochloride
Altretamine hydrochloride, also called as hexamethylmelamine hydrochloride, is an alkylating agent with apparently less toxicity compared to other cytotoxic drugs used for palliation of patients with recurrent epithelial ovarian cancer. Synonyms: 2-N,2-N,4-N,4-N,6-N,6-N-hexamethyl-1,3,5-triazine-2,4,6-triamine;hydrochloride Altretamine hydrochloride Altretamine (hydrochloride) 2975-00-0 Hexamethylmelamine HCl UNII-30FQ7QG6VM 1,3,5-Triazine-2,4,6-triamine, N,N,N',N',N'',N''-hexamethyl-, monohydroch. CAS No. 2975-00-0. Molecular formula: C9H19ClN6. Mole weight: 246.74.
Altromycin A
It is produced by the strain of Actinomycetes AB 1246E-26. It has anti-Gram-positive bacteria activity, and the MIC for Streptococcus and Staphylococcus is between 0.2-3.12ug/mL. It also has an inhibitory effect on a variety of tumor cells. Synonyms: methyl 2-(3,5-dihydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)-2-(2-(2,3-dimethyloxiran-2-yl)-11-hydroxy-10-(5-((5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-3-yl)oxy)-4,6-dimethyl-4-(methylamino)tetrahydro-2H-pyran-2-yl)-4,7,12-trioxo-7,12-dihydro-4H-naphtho[2,3-h]chromen-5-yl)-2-hydroxyacetate; D-glycero-D-manno-Octonicacid,3,7-anhydro-8-deoxy-2-C-[2-(2,3-dimethyloxiranyl)-7,12-dihydro-11-hydroxy-4,7,12-trioxo-10-[2,3,6-trideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-D-ribo-hexopyranosyl)-3-C-methyl-3-(methylamino)-a-L-lyxo-hexopyranosyl]-4H-anthra[1,2-b]pyran-5-yl]-5-O-methyl-,methyl ester, (2x)-(9CI); 4H-Anthra[1,2-b]pyran, D-glycero-D-manno-octonic acid deriv. Grades: 95%. CAS No. 128439-47-4. Molecular formula: C46H57NO18. Mole weight: 911.94.
Altromycin B
It is produced by the strain of Actinomycetes AB 1246E-26. It has anti-Gram-positive bacteria activity, and the MIC for Streptococcus and Staphylococcus is between 0.2-3.12ug/mL. It also has an inhibitory effect on a variety of tumor cells. Synonyms: GTPL10964; Octonic acid, 3,7-anhydro-8-deoxy-2-C-(2-(2,3-dimethyloxiranyl)-7,12-dihydro-11-hydroxy-4,7,12-trioxo-10-(2,3,6-trideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-D-ribo-hexopyranosyl)-3-(dimethylamino)-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-4H-anthra(1,2-b)pyran-5-yl)-5-O-methyl-, methyl ester; 4H-Anthra[1,2-b]pyran,D-glycero-D-manno-octonic acid deriv.; D-glycero-D-manno-Octonicacid,3,7-anhydro-8-deoxy-2-C-[2-(2,3-dimethyloxiranyl)-7,12-dihydro-11-hydroxy-4,7,12-trioxo-10-[2,3,6-trideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-D-ribo-hexopyranosyl)-3-(dimethylamino)-3-C-methyl-a-L-lyxo-hexopyranosyl]-4H-anthra[1,2-b]pyran-5-yl]-5-O-methyl-,methyl ester, (2x)-. Grades: 95%. CAS No. 128461-00-7. Molecular formula: C47H59NO18. Mole weight: 925.96.
altronate dehydratase
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. This enzyme participates in pentose and glucuronate interconversions. Group: Enzymes. Synonyms: D-altronate hydro-lyase. Enzyme Commission Number: EC 4.2.1.7. CAS No. 62213-26-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5055; altronate dehydratase; EC 4.2.1.7; 62213-26-7; D-altronate hydro-lyase. Cat No: EXWM-5055.
AluB I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme 80% of the lambda dna fragments can be ligated with t4 dna ligase and can be recut. Group: Restriction Enzymes. Purity: 200U; 1000U. AG↑CT TC↓GA. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer B, BSA. Storage: -20°C. Form: Liquid. Source: Arthrobacter luteus B. Pack: 10 mM Tris-HCl (pH 7.5); 200 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1019EN.
Alu I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme approximately 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. AG↑CT TC↓GA. Activity: 2000-5000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: An. E.coli strain that carries the cloned Alu I gene from Arthrobacter luteus. Pack: 10 mM Tris-HCl (pH 7.6); 100 mM NaCl; 0.1 mM EDTA; 200 μg/ml BSA; 1 mM DTT, 50% glycerol. Cat No: RE-1018EN.
Alum
Alum precipitates protein and is a strong astringent. Synonyms: Aluminum potassium sulfate anhydrous; Potassium aluminum sulfate; Potassium alum; Alumen; alum flour; alum meal; alum potassium; aluminum potassium alum; aluminum potassium disulfate; aluminum potassium sulfate; dialuminum dipotassium sulfate; kalinite; potash alum; potassium aluminum sulfate (1:1:2); rock alum; sulfuric acid aluminum potassium salt (2:1:1). CAS No. 10043-67-1. Molecular formula: KAl(SO4)2. Mole weight: 258.20.
Alum Adjuvant
Alum Adjuvant is insoluble white colloidal suspension of aluminum hydroxide used to potentiate immune response. Antigen adsorbs on the aluminum hydroxide precipitate and when injected form a depot of insoluble antigen at injection site which attracts immune cells and enhance immune response. It is used to raise polyclonal and monoclonal antibodies and is less toxic when compared to Freunds complete adjuvant. Synonyms: Mixture of Aluminum Hydroxide and Magnesium Hydroxide.
Alumatrane
Alumatrane. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ((2,2',2''-nitrilotriethanolato)(3-))-aluminu;((2,2',2''-nitrilotris(ethanolato))(3-)-n,o,o',o'')-aluminu(t-4);2',2''-nitrilotris[ethanolato]](3-)-n,o,o',o'']-[[(beta-4)-aluminu;aluminumnitrilotriethoxide;teal;ALUMATRANE;TRIETHANOLAMINE ALUMINATE;Triethan. Product Category: Organic Aluminium. CAS No. 21863-06-9. Molecular formula: C6H12AlNO3. Mole weight: 173.15. Density: 1,05 g/cm3. Product ID: ACM21863069. Alfa Chemistry ISO 9001:2015 Certified.