A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Alphaxalone. Group: Biochemicals. Grades: Purified. CAS No. 23930-19-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
alpha-Zearalanol-[d5]
Alpha-Zearalanol-[d5] is a labelled impurity of Zearalenol. Zearalenol, a resorcylic acid lactones derivative, could be produced by Fusarium fungi in grains and has been found to be an environmental contaminant. Synonyms: Zeranol-D5; (7S,11R)-2,4,11-Trihydroxy-7-methyl-7,8,9,10,11,12,13,14,15,16-decahydro-10,10,11,12,12-D5-6-oxa-benzocyclotetradecen-5-one. Grade: 95% by HPLC; 98% atom D. Molecular formula: C18H21D5O5. Mole weight: 327.43.
alpha-Zearalenol-[d5]
α-Zearalenol-[d5] is a labelled impurity of Zearalenol. Zearalenol, a resorcylic acid lactones derivative, could be produced by Fusarium fungi in grains and has been found to be an environmental contaminant. Synonyms: α-Zearalenol-d5; (E)-(7S,11R)-2,4,11-Trihydroxy-7-methyl-7,8,9,10,11,12,13,14-octahydro-10,10,11,12,12-D5-6-oxa-benzocyclotetradecen-5-one; (-)-α-Zearalenol-d5; Zearalenol-d5; trans-Zearalenol-d5; (3S,7R,11E)-3,4,5,6,7,8,9,10-Octahydro-7,14,16-trihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1-one-d5. Grade: 95% by HPLC; 98% atom D. CAS No. 36455-72-8. Molecular formula: C18H19D5O5. Mole weight: 325.41.
ALPHAZURINE A
ALPHAZURINE A. Uses: Designed for use in research and industrial production. Product Category: Acid Dyes. CAS No. 3486-30-4. Molecular formula: C37H35N2Na2O6S2. Mole weight: 713.79. Purity: CI 42080. Product ID: ACM3486304. Alfa Chemistry ISO 9001:2015 Certified. Categories: Acid blue 7.
Alphazurine A (Acid Blue 7)
25g Pack Size. Group: Analytical Reagents, Stains & Indicators. Formula: C37H35N2NaO6S2. CAS No. 3486-30-4. Prepack ID 90005052-25g. Molecular Weight 690.80337. See USA prepack pricing.
Alphitolic Acid
Alphitolic acid (Aophitolic acid) is an anti-inflammatory triterpene could found in quercus aliena. Alphitolic acid blocks Akt-NF-κB signaling to induce apoptosis. Alphitolic acid induces autophagy. Alphitolic acid has anti-inflammatory activity and down-regulates the NO and TNF-α production. Alphitolic acid can be used for cancer and inflammation research. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Powder. CAS No. 19533-92-7. Molecular formula: C30H48O4. Mole weight: 472.7. Purity: 0.98. IUPACName: (1R,3aS,5aR,5bR,7aR,9R,10R,11aR,11bR,13aR,13bR)-9,10-dihydroxy-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid. Canonical SMILES: CC(=C)C1CCC2(C1C3CCC4C(C3(CC2)C)(CCC5C4(CC(C(C5(C)C)O)O)C)C)C(=O)O. Product ID: ACM19533927. Alfa Chemistry ISO 9001:2015 Certified.
Alphitonin
Alphitonin is a metabolite related to flavonoids, which is isolated from the heartwood of Australian red ash. Alphitonin has anti-diabetic and anti-oxidant effects. Grade: >95% by HPLC. CAS No. 493-36-7. Molecular formula: C15H12O7. Mole weight: 304.25.
Alphostatin
BMG59-R2 is a peptide antibiotic produced by Bacillus megaterium BNG59-R2. It can inhibit the activity of alkaline phosphatase and also has anti-tumor activity. Synonyms: L-Glutamic acid, N-(N(sup 2)-(N-(N-L-isoleucyl-L-isoleucyl)-O-phosphono-L-seryl)-L-glutaminyl)-, hydrate; BMG59-R2. Grade: >98%. CAS No. 90119-88-3. Molecular formula: C25H45N6O13P. Mole weight: 668.63.
Alpibectir
Alpibectir is an antibacterial agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BVL-GSK098. CAS No. 2285440-39-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147241.
Alpidem selectively binds to α1β2γ2 subunit-containing GABA A receptor with an IC 50 of 17 nM and exerts anxiolytic effect [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 82626-01-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-W013150.
Alpidem
A peripheral benzodiazepine GABAA receptor ligand, a new anxiolytic. Group: Biochemicals. Alternative Names: 6-Chloro-2-(4-chlorophenyl)-N,N-dipropyl-imidazo[1,2-a]pyridine-3-acetamide; SL 80.0342-00. Grades: Highly Purified. CAS No. 82626-01-5. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Alpidem-d14
A labeled peripheral benzodiazepine GABAA receptor ligand, a new anxiolytic. Group: Biochemicals. Alternative Names: 6-Chloro-2-(4-chlorophenyl)-N,N-(dipropyl-14)-imidazo[1,2-a]pyridine-3-acetamide; SL 80.0342-00-d14. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Alpinetin
Alpinetin. Group: Biochemicals. Alternative Names: 7-Hydroxy-5-methoxyflavanone. Grades: Plant Grade. CAS No. 36052-37-6. Pack Sizes: 20mg. Molecular Formula: C16H14O4, Molecular Weight: 270.28. US Biological Life Sciences.
Worldwide
Alpinetin
Alpinetin isolated from the fruits of Alpinia katsumadai. It has strong anti-hepatoma and pancreatic cancer cells effects, by inhibiting proliferation. Uses: Antibacterial activity; anti-inflammatory activity. Synonyms: 4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-5-methoxy-2-phenyl-, (2S)-; (2S)-2,3-Dihydro-7-hydroxy-5-methoxy-2-phenyl-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-5-methoxy-2-phenyl-, (S)-; Flavanone, 7-hydroxy-5-methoxy-; (-)-Alpinetin; (S)-7-Hydroxy-5-methoxy-2-phenylchroman-4-one; 5-Methoxy-7-hydroxyflavanone; 5-O-Methylpinocembrin. Grade: ≥95%. CAS No. 36052-37-6. Molecular formula: C16H14O4. Mole weight: 270.28.
Alpinetin
Alpinetin is a flavonoid isolated from cardamom and possesses antitumor, antiinflammation, hepatoprotective, cardiovascular protective, lung protective, antibacterial, antiviral, neuroprotective properties. Alpinetin inhibits lipopolysaccharide (LPS)-induced inflammation, activates PPAR-?, activates Nrf2, and inhibits TLR4 expression to protect LPS-induced renal injury[1][2][3][4]. Uses: Scientific research. Group: Natural products. CAS No. 36052-37-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N0625A.
Alpinumisoflavone isolated from the herbs of Genista pichisermolliana. It maybe due to their ability to upregulate mechanisms promoting HDL-cholesterol and bile acid formation, Alpinumisoflavone has atheroprotective effects. Uses: Atheroprotective effects. Synonyms: 5-Hydroxy-7-(4-hydroxyphenyl)-2,2-dimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-6-one. Grade: 0.985. CAS No. 34086-50-5. Molecular formula: C20H16O5. Mole weight: 336.3.
Alprazolam-d5 solution
1.0 mg/mL in methanol, ampule of 1 mL, certified reference material. Group: Certified reference materials (crms).
Alprazolam Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Alprenolol ((RS)-Alprenolol; dl-Alprenolol) is an orally active non-selective β-adrenoceptor antagonist and an antagonist of 5-HT1A and 5-HT1B receptors. Alprenolol is used as an anti-hypertensive, anti-anginal and anti-arrhythmic agent [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (RS)-Alprenolol; dl-Alprenolol. CAS No. 13655-52-2. Pack Sizes: 50 mg; 100 mg. Product ID: HY-B1517.
Alprenolol hydrochloride
Alprenolol hydrochloride is the hydrochloride salt of alprenolol, which is a non-selective 5-HT1A receptor antagonist and beta blocker. It is used in the treatment of angina pectoris. It is no longer marketed by AstraZeneca, but may still be available from other pharmaceutical companies or generically. Uses: Adrenergic beta-antagonists. Synonyms: 1-[(1-Methylethyl)amino]-3-[2-(2-propen-1-yl)phenoxy]-2-propanol Hydrochloride; 1-(o-Allylphenoxy)-3-(isopropylamino)-2-Propanol Hydrochloride; 1-[(1-Methylethyl)amino]-3-[2-(2-propenyl)phenoxy]-2-propanol Hydrochloride; (±)-1-(o-Allylphenoxy)-3-isopropylamino-2-propanol Hydrochloride; (±)-Alprenolol Hydrochloride; 1-(2-Allylphenoxy)-2-hydroxy-3-isopropylaminopropane Hydrochloride; Alfeprol; DL-1-(o-Allylphenoxy)-3-isopropylamino-2-propanol Hydrochloride; Dimacor; Gubernal; dl-Alprenolol Chloride. Grade: ≥99% by HPLC. CAS No. 13707-88-5. Molecular formula: C15H24NO2Cl. Mole weight: 285.81.
Alprenolol hydrochloride
Alprenolol ((RS)-Alprenolol; dl-Alprenolol) hydrochloride is an orally active non-selective β-adrenoceptor antagonist and an antagonist of 5-HT1A and 5-HT1B receptors. Alprenolol hydrochloride is used as an anti-hypertensive, anti-anginal and anti-arrhythmic agent [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (RS)-Alprenolol hydrochloride; dl-Alprenolol hydrochloride. CAS No. 13707-88-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-B1517A.
Alprenolol (hydrochloride) (Standard) is the analytical standard of Alprenolol (hydrochloride). This product is intended for research and analytical applications. Alprenolol ((RS)-Alprenolol; dl-Alprenolol) hydrochloride is an orally active non-selective β-adrenoceptor antagonist and an antagonist of 5-HT1A and 5-HT1B receptors. Alprenolol hydrochloride is used as an anti-hypertensive, anti-anginal and anti-arrhythmic agent [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (RS)-Alprenolol hydrochloride (Standard); dl-Alprenolol hydrochloride (Standard). CAS No. 13707-88-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1517AR.
Alprostadil
Alprostadil. Group: Biochemicals. Grades: Purified. CAS No. 745-65-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Alprostadil
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardspharma & vet compounds & metabolitespharma & vet compounds & metabolitesapi standardseuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: 7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid,Alprostadil.
Alprostadil alfadex
Alprostadil alfadex has a protective effect on radiation-induced proliferative inhibition and apoptosis in keratinocytes and healing of radiation-induced skin injury. Synonyms: Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (11α,13E,15S)-, compd. with α-cyclodextrin (1:1); 2,4,7,9,12,14,17,19,22,24,27,29-Dodecaoxaheptacyclo[26.2.2.23,6.28,11.213,16.218,21.223,26]dotetracontane, α-cyclodextrin deriv.; α-Cyclodextrin, compd. with (11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid (1:1); G 511; PGE1 α-CD; PGE1-α-cyclodextrin inclusion compd.; Prostaglandin E1-α-cyclodextrin compd.; Prostaglandin E1-α-cyclodextrin inclusion compd.; Tandetoron. Grade: ≥95%. CAS No. 55648-20-9. Molecular formula: C36H60O30.C20H34O5. Mole weight: 1327.32.
Alprostadil Liposome
Alprostadil is a natural prostaglandin, which is important in regulating cellular functions, with effects such as dilating vascular smooth muscle and inhibiting platelet aggregation. This product is a PEGylated pre-formulated liposome with alprostadil. It is only for research purposes and for the injection to laboratory animals. Group: Drug-loaded liposome.
Alprostadil (ProstaglandinE1)
Prostaglandin E1 is a prostaglandins E. It has a role as a platelet aggregation inhibitor, a vasodilator agent, an anticoagulant and a human metabolite. Alternative Names: alprostadil. Prostaglandin E1. PGE1. Edex. CAS No. 745-65-3. Product ID: API745653. Molecular formula: C20H34O5. Mole weight: 354.5. EINECS: 212-017-2. SMILES: CCCCC[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1CCCCCCC(=O)O)O)O. Appearance: White Solid. Category: Anticoagulant & Antiplatelet APIs.
Alprostadil (Prostaglandin E1) EP Impurity A
Alprostadil (Prostaglandin E1) EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 14152-28-4. Molecular formula: C20H32O4. Mole weight: 336.47. Catalog: APB14152284.
Alprostadil (Prostaglandin E1) EP Impurity B
Alprostadil (Prostaglandin E1) EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 13345-51-2. Molecular formula: C20H32O4. Mole weight: 336.47. Catalog: APB13345512.
Alprostadil (Prostaglandin E1) Impurity 19
Alprostadil (Prostaglandin E1) Impurity 19. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10164-73-5. Molecular formula: C20H36O5. Mole weight: 356.5. Catalog: APB10164735.
ALPS
ALPS(N-Ethyl-N-sulfopropylaniline sodium salt) is a bio-chemical reagents/chromogenic reagent. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: N-Ethyl-N-sulfopropylaniline sodium salt. CAS No. 82611-85-6. Pack Sizes: 50 mg; 100 mg. Product ID: HY-15905.
Alq3
Alq3. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Tris(8-hydroxy-quinolinato)aluminium. Product Category: Organic Light Emitting Diode (OLED). Appearance: yellow-green crystalline powder. CAS No. 2085-33-8. Molecular formula: C27H18AlN3O3. Mole weight: 459.43 g/mol. Purity: 95%+. IUPACName: Tri(quinolin-8-yloxy)alumane. Canonical SMILES: C1=CC2=C(C(=C1)O[Al](OC3=CC=CC4=C3N=CC=C4)OC5=CC=CC6=C5N=CC=C6)N=CC=C2. Product ID: ACM2085338-9. Alfa Chemistry ISO 9001:2015 Certified.
Alrefimotide
Alrefimotide is an immunological agent for active immunization. Synonyms: telomerase reverse transcriptase (human TERT, hTERT, EC:2.7.7.49) (660-689)-peptide; L-alanyl-L-leucyl-L-phenylalanyl-L-seryl-L-valyl-L-leucyl-L-asparaginyl-L-tyrosyl-L-α-glutamyl-L-arginyl-L-alanyl-L-arginyl-L-arginyl-L-prolylglycyl-L-leucyl-L-leucylglycyl-L-alanyl-L-seryl-L-valyl-L-leucylglycyl-L-leucyl-L-α-aspartyl-L-α-aspartyl-L-isoleucyl-L-histidyl-L-arginyl-L-alanine; Telomerase reverse transcriptase 660-689 peptide antigen. CAS No. 1331848-79-3. Molecular formula: C146H239N45O41. Mole weight: 3280.78.
Alrestatin
Alrestatin is an inhibitor of aldose reductase (IC50 = 148 μM). Uses: Specific inhibitor of aldose reductase. Synonyms: Alrestatine; 2-(1,3-dioxobenzo[de]isoquinolin-2-yl)acetic acid. Grade: ≥98%. CAS No. 51411-04-2. Molecular formula: C14H9NO4. Mole weight: 255.23.
Alrestatin
Alrestatin. Group: Biochemicals. Grades: Purified. CAS No. 51411-04-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Alrestatin
Alrestatin is an inhibitor of aldose reductase, an enzyme involved in the pathogenesis of complications of diabetes mellitus, including diabetic neuropathy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AY-22284. CAS No. 51411-04-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1202.
Alrestatin (sodium)
Alrestatin sodium is a specific inhibitor of aldose reductase (IC50 = 148 μM). Uses: A specific inhibitor of aldose reductase. Synonyms: Sodium; 2-(1,3-dioxobenzo[de]isoquinolin-2-yl)acetate. Grade: ≥98%. CAS No. 51876-97-2. Molecular formula: C14H8NNaO4. Mole weight: 277.21.
a-L-Rhamnopyranosyl bromide triacetate
a-L-Rhamnopyranosyl bromide triacetate is a comprehensive compound with extraordinary antiviral potency, used for research of a wide range of viral infections, including the formidable influenza and herpes. Synonyms: (2S,3R,4R,5S,6S)-2-Bromo-6-methyltetrahydro-2H-pyran-3,4,5-triyl triacetate; 2,3,4-tri-O-acetyl-alpha-L-rhamnopyranosyl bromide. Grade: 97%. CAS No. 5158-64-5. Molecular formula: C12H17BrO7. Mole weight: 353.16.
a-L-Rhamnopyranosyl bromide tribenzoate
a-L-Rhamnopyranosyl bromide tribenzoate is an intriguing chemical compound famed for its antimicrobial capabilities, garnering considerable research in the fight against diverse infectious diseases arising from both bacterial and fungal sources. Synonyms: 2,3,4-Tri-O-benzoyl-a-L-rhamnopyranosyl bromide. CAS No. 53297-33-9. Molecular formula: C27H23BrO7. Mole weight: 539.4.
Alrizomadlin
Alrizomadlin (APG-115) is an orally active MDM2 protein inhibitor binding to MDM2 protein with IC 50 and K i values of 3.8 nM and 1 nM, respectively [1]. Alrizomadlin blocks the interaction of MDM2 and p53 and induces cell-cycle arrest and apoptosis in a p53-dependent manner [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: APG-115; AA-115. CAS No. 1818393-16-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101518.
Alrizomadlin
Alrizomadlin is a highly potent and chemically stable E3 ubiquitin-protein ligase Mdm2 (Hdm2) inhibitor. It is used in the treatment and prevention of osteoarthritis. Synonyms: APG-115; AA-115; 4-((3'R,4'S,5'R)-6''-Chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamido)bicyclo[2.2.2]octane-1-carboxylic acid; APG115; APG 115; NSC831270. Grade: >98%. CAS No. 1818393-16-6. Molecular formula: C34H38Cl2FN3O4. Mole weight: 642.59.
ALS-8176 (active form)
ALS-8176 (active form), a 4'-substituted cytidine analogue, is a potent, selective RSV polymerase inhibitor. It has an EC50 of 0.15 μM in the RSV replicon assay and an IC50= 0.02 μM due to its corresponding 5'-triphosphate in the RSV polymerase assay. Synonyms: 4-amino-1-[(2R,3R,4R,5R)-5-(chloromethyl)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-oneALS-8176 (active form); ALS-8112; ALS8112; ALS 8112.UNII-7795987MKM7795987MKMCHEMBL3417243SCHEMBL15070479CS-5472; HY-12983; CS 5472; HY 12983; CS5472; HY129834'-Chloromethyl-2'-deoxy-2'-fluorocytidineCytidine. Grade: 99.67%. CAS No. 1445379-92-9. Molecular formula: C10H13ClFN3O4. Mole weight: 293.68.
alseroxylon
alseroxylon. Uses: Designed for use in research and industrial production. Additional or Alternative Names: alseroxylon. Product Category: Heterocyclic Organic Compound. CAS No. 8001-95-4. Mole weight: 281.8259. Density: g/cm³. Product ID: ACM8001954. Alfa Chemistry ISO 9001:2015 Certified.
Alsevalimab
Alsevalimab is a human monoclonal antibody against B7-H4 [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2254029-91-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99242.
Alsevalimab
Alsevalimab is a human monoclonal antibody that targets B7-H4 with potential antineoplastic and immune checkpoint inhibitory activities. CAS No. 2254029-91-7.
ALS-I
ALS-I, an acid-Liable surfactant, is adopted for in-solution enzymatic digestions, can help to solubilize hydrophobic proteins. ALS-I is significantly enhanced peptide recovery for mass spectrometry (MS) mapping in the study of the proteomes of regenerating rat retina and mouse brain [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 308818-13-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-44157.
Also Nameel F46 Tubing
Also Nameel F46 Tubing. Group: Polymers.
Alsterpaullone
Potent CDK1/cyclin B (IC50 = 35 nM) inhibitor. Anti-tumor compound Potent inhibitor of CDK2/cyclin A, CDK2/cyclin E (IC50 = 200 nM), CDK5/p25 (IC50 = 40 nM), CDK5/p35 (IC50 = 40 nM). GSK-3beta (glycogen synthase kinase-3beta) inhibitor. Apoptosis inhibitor. Apoptosis inducer. Angiogenesis inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 237430-03-4. Pack Sizes: 1mg, 5mg. Molecular Formula: C16H11N3O3. US Biological Life Sciences.
Worldwide
Alsterpaullone
Alsterpaullone is a potent glycogen synthase kinase-3 inhibitor and a potential therapeutic agent for the treatment of Parkinson disease. Alsterpaullone is also known as 9-Nitropaullone and NSC 705701, which is a derivative of kenpaullone and an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) and glycogen synthase kinase 3β (GSK3β). Alsterpaullone induces apoptosis by activation of caspase-9 due to perturbation in mitochondrial membrane potential. Alsterpaullone is a derivative of kenpaullone with slightly improved potency over kenpaullone, alsterpaullone selectively inhibits Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p25, and GSK3α/β with IC50 values of 35, 15, 200, 40, and 4 nM, respectively. Synonyms: 9-Nitropaullone; NSC 705701; 7,12-Dihydro-9-nitro-indolo[3,2-d][1]benzazepin-6(5H)-one. Grade: ≥98%. CAS No. 237430-03-4. Molecular formula: C16H11N3O3. Mole weight: 293.3.
Alsterpaullone (9-Nitropaullone) is a potent CDK inhibitor, with IC50s of 35 nM, 15 nM, 200 nM and 40 nM for CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E and CDK5/p35, respectively. Alsterpaullone also competes with ATP for binding to GSK-3alpha/GSK-3beta with IC50s of both 4 nM. Alsterpaullone has antitumor activity, and possesses potential for the study in neurodegenerative and proliferative disorders[1]. Alsterpaullone induces apoptosis in leukemia cell line[2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 9-Nitropaullone; NSC 705701. CAS No. 237430-03-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108359.
Alsterpaullone
Alsterpaullone (9-Nitropaullone) is a potent CDK inhibitor, with IC50s of 35 nM, 15 nM, 200 nM and 40 nM for CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E and CDK5/p35, respectively. Alsterpaullone also competes with ATP for binding to GSK-3alpha/GSK-3beta with IC50s of both 4 nM. Alsterpaullone has antitumor activity, and possesses potential for the study in neurodegenerative and proliferative disorders. Alsterpaullone induces apoptosis in leukemia cell line. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 237430-03-4. Molecular formula: C16H11N3O3. Mole weight: 293.28. Purity: >95%. Product ID: ACM237430034. Alfa Chemistry ISO 9001:2015 Certified.
Alsterpaullone, 2-Cyanoethyl - CAS 852529-97-0
A cell-permeable and reversible Alsterpaullone derivative that acts as a highly potent, ATP-competitive, selective inhibitor of Cdk1/cyclin B and GSK-3?. Group: Fluorescence/luminescence spectroscopy.
Alsterpaullone - CAS 237430-03-4
A cell-permeable, potent, reversible, and ATP competitive inhibitor of GSK-3? (IC?? = 4 nM) and Cdk1/cyclin B (IC?? = 35 nM). Group: Fluorescence/luminescence spectroscopy.
Alstolenine
Alstolenine is an alkaloid compound found in the Alstonia venenata. Synonyms: Deacetylakuammiline trimethylgallate. Grade: >95%. CAS No. 85769-33-1. Molecular formula: C31H34N2O7. Mole weight: 546.6.
Alstonic acid A
Alstonic acid A can be found in the herbs of Alstonia scholaris. Synonyms: (3alpha,4beta)-3-(1,1-Dimethyl-2-oxoethyl)-4,8,9,20-tetramethyl-19-norpregn-5(10)-ene-4-acetic acid. Grade: >98%. CAS No. 1159579-44-8. Molecular formula: C30H48O3. Mole weight: 456.7.
Alstonic acid B
Alstonic acid B is a natural compound isolated from the herbs of Alstonia scholaris. Synonyms: Alstonic acid B; 1159579-45-9; 2-[(1R,4S,5R,8R,9R,12S,16R,19S)-4,9,12,17,17,19-hexamethyl-18-oxo-8-propan-2-yl-19-pentacyclo[14.2.1.01,13.04,12.05,9]nonadec-13-enyl]acetic acid; ZINC96023603; AKOS032962124. Grade: 98.0%. CAS No. 1159579-45-9. Molecular formula: C30H46O3. Mole weight: 454.695.
Altanserin
Altanserin can synthesize Fluorine-18 Altanserin. Fluorine-18 Altanserin binds to the brain 5HT 2 receptors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 76330-71-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119156.
Altanserin hydrochloride
Altanserin hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1135280-78-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Altanserin hydrochloride
Altanserin hydrochloride is the hydrochloride salt of altanserin, which is a selective and potent 5-HT2A receptor antagonist with Ki value of 0.13 nM. It is centrally active following systemic administration in vivo. It is also a useful intermediate for organic synthesis. Synonyms: 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone hydrochloride. Grade: ≥98% by HPLC. CAS No. 1135280-78-2. Molecular formula: C22H23FN3O2SCl. Mole weight: 447.95.
Altechromone A is produced from Alternaria brassicicola ML-P08. Altechromone A shows antimicrobial activity against Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens and Candida albicans with the MICs of 3.9, 3.9, 1.8, and 3.9 ug/ml, respectively. Synonyms: 7-Hydroxy-2,5-dimethylchromone; 7-Hydroxy-2,5-dimethyl-4H-1-benzopyran-4-one. Grade: 98.0%. CAS No. 38412-47-4. Molecular formula: C11H10O3. Mole weight: 190.19.
Alteichin
It is produced by the strain of Alternaria eichorniae. Phytotoxic substances. Synonyms: alterperylenol; Alteichin; GRK18WHV7F; C10295; (+)-Alterperylenol; AC1L2PAW; Alterperylnol; CHEBI:2614; DTXSID10237401; ZINC4098645; AKOS030213167; (1S,12aR,12bS)-1,4,9,12a-tetrahydroxy-2,12b-dihydro-1H-perylene-3,10-dione; Q27105736; 3,10-Perylenedione,1,2,12a,12b-tetrahydro-1,4,9,12a-tetrahydroxy-, (1S,12aR,12bS)-; 3,10-Perylenedione, 1,2,12a,12b-tetrahydro-1,4,9,12a-tetrahydroxy-, (1alpha,12abeta,12balpha)-(+)-. Grade: 95%. CAS No. 88899-62-1. Molecular formula: C20H14O6. Mole weight: 350.32.
Altemicidin
It is produced by the strain of Streptomyces sioyaensis. It has acaricidal and anti-tumor activity. The inhibition IC50 of L1210 and IMC cancer cells was 0.84 and 0.82 ?/mL. Synonyms: CTK4B4358; DTXSID20925120; 1H-Cyclopenta[c]pyridine-7-carboxylicacid,4-(aminocarbonyl)-7-[[2-(aminosulfonyl)acetyl]amino]-2,4a,5,6,7,7a-hexahydro-6-hydroxy-2-methyl-,(4aR,6S,7R,7aS)-; LS-136376; Q15410226; 6-Hydroxy-7-({[(1-hydroxy-2-sulfamoylethylidene)amino]oxy}carbonyl)-2-methyl-2,4a,5,6,7,7a-hexahydro-1H-cyclopenta[c]pyridine-4-carboximidic acid. Grade: 99%. CAS No. 125399-82-8. Molecular formula: C13H20N4O7S. Mole weight: 376.38.
Alteminostat
Alteminostat is a histone deacetylase inhibitor and antineoplastic drug candidate. Alteminostat inhibits the class I-II HDAC family via histone H3 and tubulin acetylation. Uses: Histone deacetylase inhibitors. Synonyms: 1-Piperazinecarboxamide, N-(7-(hydroxyamino)-7-oxoheptyl)-4-methyl-N-(4-(1-methyl-1H-indazol-6-yl)phenyl)-; CKD-581. CAS No. 1246374-97-9. Molecular formula: C27H36N6O3. Mole weight: 492.61.
Altenuene
(-)-Altenuene is a toxin isolated from the fungus Alternaria tenuis. It has antioxidant activity and inhibits cholinesterases. Synonyms: (2R,3R,4aR)-2,3,4,4a-Tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-6H-dibenzo[b,d]pyran-6-one. Grade: >95%. CAS No. 29752-43-0. Molecular formula: C15H16O6. Mole weight: 292.29.