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| Product | Description | |
|---|---|---|
| Bryostatin 3 | Bryostatin 3 has been found to be a potent protein kinase C activator and could probably be useful in studies of emerging cancers. Synonyms: Bryostatin 3; 143370-84-7; (4S,5S,7E,9R,11Z,13S,15S,17S,19R,21R,25R,27R,27aS)-17-(Acetyloxy)-4,5,6,9,10,11,12,13,14,15,16,17,18,19, 20,21,22,23,25,26,27,27a-docosahydro-5,15,21-trihydroxy-25-[(1R)-1-hydroxyethyl]-11-(2-methoxy-2-oxoethylidene)-6,6,16,16-tetramethyl-2,23-dioxo-5,27:9,13:15,19-triepoxy-2H-furo[2,3-e]oxacyclohexacosin-4-yl-(2E,4E)-2,4-octadienoic acid ester. Grade: ≥95% by HPLC. CAS No. 143370-84-7. Molecular formula: C46H64O17. Mole weight: 888.99. |  |
| BS181 | BS-181 is a highly selective CDK inhibitor for CDK7 with an IC(50) of 21 nmol/L. Testing of other CDKs as well as another 69 kinases showed that BS-181 only inhibited CDK2 at concentrations lower than 1 micromol/L, with CDK2 being inhibited 35-fold less potently (IC(50) 880 nmol/L) than CDK7. In MCF-7 cells, BS-181 inhibited the phosphorylation of CDK7 substrates, promoted cell cycle arrest and apoptosis to inhibit the growth of cancer cell lines, and showed antitumor effects in vivo. The drug was stable in vivo with a plasma elimination half-life in mice of 405 minutes after i.p. administration of 10 mg/kg. The same dose of drug inhibited the growth of MCF-7 human xenografts in nude mice. BS-181 therefore provides the first example of a potent and selective CDK7 inhibitor with potential as an anticancer agent. Synonyms: BS-181; BS181; BS 181. CAS No. 1092443-52-1. Molecular formula: C22H32N6. Mole weight: 380.53. | |
| BS 181 dihydrochloride | BS 181 dihydrochloride is a selective CDK7 inhibitor (IC50 = 21 nM) displaying >40-fold selectivity for CDK7 over others CDKs. BS 181 promotes cell cycle arrest and apoptosis in a range of cancer cells in MCF-7 cells and inhibits MCF-7 tumor xenograft growth in mice. Synonyms: BS 181 dihydrochloride; BS181 dihydrochloride; BS-181 dihydrochloride; N5-(6-Aminohexyl)-3-(1-methylethyl)-N7-(phenylmethyl)pyrazolo[1,5-a]pyrimidine-5,7-diamine dihydrochloride. Grade: ≥99% by HPLC. Molecular formula: C22H32N6.2HCl. Mole weight: 453.45. | |
| BS-181 dihydrochloride | BS-181 dihydrochloride is a potent and selective CDK7 inhibitor, with IC50s of 21, 880, 3000 and 4200 nM against CDK7, CDK2, CDK5 and CDK9 (fails to block CDK1, 4 and 6), respectively. It promotes cell cycle arrest and apoptosis in a range of cancer cells in vitro, and inhibits the xenograft growth of MCF-7 tumors in mice. Synonyms: N5-(6-Aminohexyl)-3-(1-methylethyl)-N7-(phenylmethyl)pyrazolo[1,5-a]pyrimidine-5,7-diamine Dihydrochloride; N5-(6-Aminohexyl)-N7-benzyl-3-isopropylpyrazolo[1,5-a]pyrimidine-5,7-diamine dihydrochloride; Pyrazolo[1,5-a]pyrimidine-5,7-diamine, N5-(6-aminohexyl)-3-(1-methylethyl)-N7-(phenylmethyl)-, hydrochloride (1:2). Grade: ≥95%. CAS No. 1883548-83-1. Molecular formula: C22H34Cl2N6. Mole weight: 453.45. | |
| BS-181 HCl | BS-181 HCl is a highly selective CDK7 inhibitor with IC50 of 21 nM. It is more than 40-fold selective for CDK7 than CDK1, 2, 4, 5, 6, or 9. Synonyms: BS-181 HCl; BS 181 HCl; BS181 HCl. Grade: >98%. CAS No. 1397219-81-6. Molecular formula: C22H32N6.HCl. Mole weight: 416.99. | |
| BS-181 hydrochloride | BS-181 hydrochloride is a highly selective CDK7 inhibitor with IC50 of 21 nM, and > 40-fold selective for CDK7 than CDK1, 2, 4, 5, 6, or 9. Uses: Scientific research. Group: Signaling pathways. CAS No. 1397219-81-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13266A. |  |
| BS3 Crosslinker | BS3 Crosslinker is a water-soluble, homobifunctional protein crosslinker. Group: Biochemicals. Alternative Names: Bis-sulfosuccinimidyl Suberate, BS3, Sulfo-DSS, Bis-sulfo-succinimidyl Suberatebissulfosuccin imidyl Suberate, Sulfo-DSS, Suberic Acid sulfoNHS Ester, BSSS, BS3-d0, Sodium 1, 1- (octanedioylbis (oxy))bis (2, 5-dioxopyrrolidine-3-sulfonate), BS3 Protein Crosslinker. Grades: Purified. CAS No. 82436-77-9. Pack Sizes: 50mg, 250mg. US Biological Life Sciences. |  Worldwide |
| BS3 Crosslinker | BS3 Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 82436-77-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124329. | |
| B-S-(4-Methoxybenzylmercapto)-b,b-cyclopentamethylene-propionic acid | B-S-(4-Methoxybenzylmercapto)-b,b-cyclopentamethylene-propionic acid. Group: Biochemicals. Alternative Names: [1- (4-Methoxybenzylsulfanyl) cyclohexyl]acetic acid. Grades: Highly Purified. CAS No. 87242-92-0. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C16H22O3S. US Biological Life Sciences. | Worldwide |
| b-S-(4-Methoxybenzylmercapto)-b,b-cyclopentamethylene-propionic acid 99+% (TLC) | b-S-(4-Methoxybenzylmercapto)-b,b-cyclopentamethylene-propionic acid 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 87242-92-0. Pack Sizes: 1g, 5g. US Biological Life Sciences. | Worldwide |
| B-S- (4-Methoxybenzylmercapto) isovaleric acid | B-S- (4-Methoxybenzylmercapto) isovaleric acid. Group: Biochemicals. Alternative Names: 3-(4-Methoxy-benzylsulfanyl)-3-methyl butyric acid. Grades: Highly Purified. CAS No. 268219-99-4. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C13H18O3S. US Biological Life Sciences. | Worldwide |
| b-S- (4-Methoxybenzylmercapto) isovaleric acid 99+% (TLC) | b-S- (4-Methoxybenzylmercapto) isovaleric acid 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences. | Worldwide |
| Bsa29 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (dam-) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. AT↑CGAT TAGC↓TA. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer G, BSA (except E205T and E206T). Storage: -20°C. Form: Liquid. Source: Bacillus stearothermophilus 29. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1041RE. |  |
| BSA for protein quantitation | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. |  |
| BSA+TMCS | for GC derivatization, 93.0-97.0% (GC). Group: Derivatization reagents gc. | |
| BSB | BSB. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4,4'-Di(triphenylsilyl)-biphenyl. Product Category: Organic Light Emitting Diode (OLED). CAS No. 18826-13-6. Molecular formula: C48H38Si2. Mole weight: 670.99 g/mol. Product ID: ACM18826136-1. Alfa Chemistry ISO 9001:2015 Certified. |  |
| BSB | BSB is a Congo red-derived fluorescent probe. BSB binds not only to extracellular amyloid β protein, but also many intracellular lesions composed of abnormal tau and synuclein proteins. BSB acts as a prototype imaging agent for Alzheimer's disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (trans,trans)-1-Bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene. CAS No. 291766-06-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-D1443. | |
| BSB4 | BSB4. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4,4'-Bis(4-(9H-carbazol-9-yl)styryl)biphenyl. Product Category: Organic Light Emitting Diode (OLED). CAS No. 850594-34-2. Molecular formula: C52H36N2. Mole weight: 688.86 g/mol. Product ID: ACM850594342. Alfa Chemistry ISO 9001:2015 Certified. | |
| BSBF | BSBF. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-(9,9-Spirobifluoren-2-yl)-9,9-spirobifluorene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 664345-18-0. Molecular formula: C50H30. Mole weight: 630.77 g/mol. Product ID: ACM664345180. Alfa Chemistry ISO 9001:2015 Certified. Categories: BSFA Award for Best Artwork. | |
| BSc2118 | BSc2118 is a potent proteasome inhibitor. BSc2118 shows significant antimyeloma activity and may be considered as a promising agent in cancer drug development. BSc2118 is also a promising new candidate for stroke therapy, which may in addition alleviate recombinant tissue-plasminogen activator-induced brain toxicity. Synonyms: BSc-2118; BSc 2118. Grade: 98%. CAS No. 863924-64-5. Molecular formula: C28H43N3O7. Mole weight: 533.66. | |
| BSc3094 monohydrobromide | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Bsc4 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 55°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500U; 2500U. CCNNNNN↑NNGG GGNN↓NNNNNCC. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer W, BSA. Storage: -20°C. Form: Liquid. Source: Bacillus schlegelii 4. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1042RE. | |
| BSc5367 | BSc5367 is a potent Nek1 inhibitor with an IC50 of 11.5 nM. NIMA-related protein kinase Nek1 is crucially involved in cell cycle regulation, DNA repair and microtubule regulation and dysfunctions of Nek1 play key roles in amyotrophic lateral sclerosis (ALS), polycystic kidney disease (PKD) and several types of radiotherapy resistant cancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3029584-84-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144425. | |
| BSc5371 | BSc5371 is a potent and irreversible inhibitor of FLT3, with Kds of 1.3, 0.83, 1.5, 5.8 and 2.3 nM for mutant FLT3(D835H), FLT3(ITD, D835V), FLT3(ITD, F691L), FLT3-ITD and wild type FLT3wt, respectively. It is cytotoxic to FLT3-dependent cell lines. Synonyms: N-[2-(Diethylamino)ethyl]-2,4-dimethyl-5-[(Z)-{2-oxo-5-[(vinylsulfonyl)amino]-1,2-dihydro-3H-indol-3-ylidene}methyl]-1H-pyrrole-3-carboxamide; 1H-Pyrrole-3-carboxamide, N-[2-(diethylamino)ethyl]-5-[(Z)-[5-[(ethenylsulfonyl)amino]-1,2-dihydro-2-oxo-3H-indol-3-ylidene]methyl]-2,4-dimethyl-. Grade: ≥95%. CAS No. 2286419-03-0. Molecular formula: C24H31N5O4S. Mole weight: 485.60. | |
| Bse118 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 65°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. R↑CCGGY YGGCC↓R. Activity: 2000-5000u.a./ml. Appearance: 10 X SE-buffer O. Storage: -20°C. Form: Liquid. Source: Bacillus stearothermophilus 118. Pack: 10 mM KH2PO4 (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA; 50% glycerol. Cat No: ET-1044RE. | |
| Bse1 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 65°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme >95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. ACTGGN↑ TGAC↓CN. Activity: 10000-20000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: Bacillus stearothermophilus 1. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA; 50% glycerol. Cat No: ET-1043RE. | |
| Bse21 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (HindIII-digest) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 2-fold overdigestion with enzyme about 50% of dna fragments can be ligated by using of high concentration t4 dna ligase with presence of 10% peg. of these more than 90% can be recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. CC↑TNAGG GGANT↓CC. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: Bacillus species 21. Pack: 10 mM KH2PO4 (pH 7.4); 50 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1045RE. | |
| Bse3D I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 60°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. GCAATGNN↑ CGTTAC↓NN. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer G. Storage: -20°C. Form: Liquid. Source: Bacillus stearothermophilus 3D. Pack: 10 mM Tris-HCl (pH 7.5); 200 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 50% glycerol. Cat No: ET-1046RE. | |
| Bse8 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 60°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme about 80% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. GATNN↑NNATC CTANN↓NNTAG. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer G. Storage: -20°C. Form: Liquid. Source: Bacillus species 8. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA; 50% glycerol. Cat No: ET-1047RE. | |
| BseP I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 50°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. G↑CGCGC CGCGC↓G. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer G. Storage: -20°C. Form: Liquid. Source: Bacillus stearothermophilus P. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 10 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1048RE. | |
| BseX3 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 50°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme more than 90% of dna fragments can be ligated. of these 80% can be recut. Group: Restriction Enzymes. Purity: 200U; 1000U. C↑GGCCG GCCGG↓C. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer O. Storage: Store at -20°C. Storage at -70 °C is recommended for periods longer than 3 months. Form: Liquid. Source: Bacillus stearothermophilus X3. Pack: 10 mM Tris-HCl (pH 8.2); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1049RE. | |
| BSH-IN-1 | BSH-IN-1 is a covalent inhibitor of bile salt hydrolases. BSH-IN-1 inhibits the bile salt hydrolases of the Gram-negative bacterium B. theta and the Gram-positive bacterium B. longum (IC50s = 427 and 108 nM, respectively). It also inhibits deconjugation of bile acids in a variety of bacteria and in resuspended mouse feces. Synonyms: (R)-5-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-1-fluorohexan-2-one. Grade: ≥98%. CAS No. 2553217-91-5. Molecular formula: C25H41FO3. Mole weight: 408.59. | |
| b-Sitosterol b-D-glucuronide methyl ester | b-Sitosterol b-D-glucuronide methyl ester is a notable biomedical compound with potent anticancer attributes. Also, it exhibits insulin sensitivity in the realm of diabetes research. Molecular formula: C36H60O7. Mole weight: 604.86. | |
| b-Sitosterol ≥40% | b-Sitosterol ≥40%. Group: Biochemicals. Grades: Highly Purified. CAS No. 83-46-5. Pack Sizes: 250g, 500g, 1kg, 2kg, 5kg. US Biological Life Sciences. | Worldwide |
| b-Sitosterol ≥40% (HPLC) | b-Sitosterol ≥40% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 83-46-5. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| b-Sitosterol ≥70% | b-Sitosterol ≥70%. Group: Biochemicals. Grades: Highly Purified. CAS No. 83-46-5. Pack Sizes: 10g, 25g, 50g, 100g. US Biological Life Sciences. | Worldwide |
| b-Sitosterol ≥80%. | Loss on drying: Group: Biochemicals. Grades: Highly Purified. CAS No. 83-46-5. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. US Biological Life Sciences. | Worldwide |
| BSJ-01-175 | Bsj-01-175, a potent and selective covalent inhibitor of CDK12/13, shows exquisite selectivity, potent inhibition of RNA polymerase II phosphorylation, and downregulation of CDK12-targeted genes in cancer cells. Synonyms: 2-Butenamide, N-[4-[[(1R,3R)-3-[[5-chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]cyclohexyl]oxy]phenyl]-4-(dimethylamino)-, (2E)-. CAS No. 2227392-55-2. Molecular formula: C30H33ClN6O2. Mole weight: 545.08. | |
| BSJ-03-123 | BSJ-03-123 is a potent, CDK6-selective small-molecule degrader (PROTAC) that uniquely enables rapid pharmacological interrogation of CDK6-dependent functions; induces differential E3 ligase recruitment and ensuing degradation of CDK6, but not CDK4. Synonyms: BSJ 03-123; BSJ 03 123; BSJ-03 123; BSJ03123; N-[2-(2-{2-[2-(4-{6-[(6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl}-1-piperazinyl)ethoxy]ethoxy}ethoxy)ethyl]-2-{[2-(2,6-dioxo-3-piperidinyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}acetamide; Acetamide, N-[2-[2-[2-[2-[4-[6-[(6-acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinyl]ethoxy]ethoxy]ethoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-. Grade: ≥95%. CAS No. 2361493-16-3. Molecular formula: C47H56N10O11. Mole weight: 937.01. | |
| BSJ-03-123 | BSJ-03-123 is a PROTAC connected by ligands for Cereblon and CDK as a potent and novel CDK6-selective small-molecule degrader. Uses: Scientific research. Group: Signaling pathways. CAS No. 2361493-16-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111556. | |
| BSJ-03-204 | BSJ-03-204 is a PROTAC connected by ligands for Cereblon and CDK. BSJ-03-204 is a potent and selective Palbociclib-based CDK4/6 dual degrader (PROTAC), with IC50s of 26.9 nM and 10.4 nM for CDK4/D1 and CDK6/D1, respectively. BSJ-03-204 does not induce IKZF1/3 degradation and has anti-cancer activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2349356-09-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136250. | |
| BSJ-04-122 | BSJ-04-122 is a covalent MKK4/7 dual inhibitor. BSJ-04-122 inhibits MKK4 and MKK7 with IC50 values of 4 nM and 181 nM, respectively. BSJ-04-122 can be used for the research of cancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2513289-74-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152185. | |
| BSJ-4-116 | BSJ-4-116 is a PROTAC connected by ligands for Cereblon and CDK. BSJ-4-116 is a highly potent and selective CDK12 degrader (PROTAC) with an IC50 of 6 nM. BSJ-4-116 downregulates DDR genes through a premature termination of transcription, primarily through increasing poly(adenylation). BSJ-4-116 exhibits potent antiproliferative effects, alone and in combination with the poly(ADP-ribose) polymerase inhibitor Olaparib (HY-10162)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2519823-34-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139039. | |
| BSJ-Bump | BSJ-Bump is the negative control for BSJ-03-123. It displays binding and no degradation of cyclin dependent kinases 6 (CDK6) in vitro. Synonyms: N-(2-(2-(2-(2-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)ethoxy)ethoxy)ethoxy)ethyl)-2-((2-(1-methyl-2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide. Grade: ≥98%. CAS No. 2409918-48-3. Molecular formula: C48H58N10O11. Mole weight: 951.05. | |
| BSK-H Medium | With sodium bicarbonate, suitable for Borrelia burgdorferi (Qualified). Group: Fluorescence/luminescence spectroscopy. | |
| BSK-H Medium, Complete | sterile-filtered, with 6% rabbit serum, suitable for Borrelia burgdorferi. Group: Fluorescence/luminescence spectroscopy. | |
| BslF I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 3-fold overdigestion with enzyme 90% of dna fragments can be ligated and 95% of these can be recut. Group: Restriction Enzymes. Purity: 100U; 500U. GGGAC(N)10↑ CCCTG(N)14&darr. Activity: 1000u.a./ml. Appearance: 10 X SE-buffer Y, BSA. Storage: -20°C. Form: Liquid. Source: Bacillus stearothermophilus Fl. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 50% glycerol. Cat No: ET-1050RE. | |
| Bso31 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of T7 DNA in 1 hour at 55°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme more than 90% of dna fragments can be ligated. of these 80% can be recut. Group: Restriction Enzymes. Purity: 200U; 1000U. GGTCTC(N)1↑ CCAGAG(N)5&darr. Activity: 5000-10000u.a./ml. Appearance: 10 X SE-buffer O, BSA. Storage: -20°C. Form: Liquid. Source: Bacillus stearothermophilus 31. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA; 50% glycerol. Cat No: ET-1051RE. | |
| Bsp13 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (dam-) in 1 hour at 50°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. T↑CCGGA AGGCC↓T. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer 2K. Storage: -20°C. Form: Liquid. Source: Bacillus species 13. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1052RE. | |
| Bsp1720 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme about 80% of dna fragment can be ligated. of these about 95% can be recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. GC↑TNAGC CGANT↓CG. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer G. Storage: -20°C. Form: Liquid. Source: Bacillus species 1720. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 50% glycerol. Cat No: ET-1053RE. | |
| Bsp19 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. C↑CATGG GGTAC↓C. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer 2W, BSA. Storage: -20°C. Form: Liquid. Source: Bacillus species 19. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1054RE. | |
| BspAC I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme more than 95% of the lambda dna fragments can be ligated with t4 dna ligase at 16°c and 50% of these can be recut. Group: Restriction Enzymes. Purity: 200U; 1000U. C↑CGC GGC↓G. Activity: 2000-5000u.a./ml. Appearance: 10 X SE-buffer O, BSA. Storage: -20°C. Form: Liquid. Source: Bacillus species AC. Pack: 10 mM KH2PO4(pH 7.2); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1055RE. | |
| BspFN I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme more than 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. CG↑CG GC↓GC. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: Bacillus species FN. Pack: 20 mM Tris-HCl (pH 7.5); 300 mM NaCl; 0.1 mM EDTA; 200 μg/ml BSA, 7 mM 2-mercaptoethanol and 50% glycerol. Cat No: ET-1056RE. | |
| BssEC I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 60°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. C↑CNNGG GGNNC↓C. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: Bacillus stearothermophilus EC. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1057RE. | |
| BssNA I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme more than 90% of dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. GTA↑TAC CAT↓ATG. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer W, BSA. Storage: -20°C. Form: Liquid. Source: Bacillus stearothermophilus NA. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA; 50% glycerol. Cat No: ET-1058RE. | |
| BSSS | BSSS. CAS No. 84236-77-9. Pack Sizes: Milligram Quantities: 100 mg. Order Number: CL101. |  www.prochemonline.com |
| BssT1 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 60°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. C↑CWWGG GGWWC↓C. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer 2K. Storage: -20°C. Form: Liquid. Source: Bacillus stearothermophilus T1. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1059RE. | |
| BST | BST. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4,4''-Di(triphenylsilyl)-p-terphenyl. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1046146-39-7. Molecular formula: C54H42Si2. Mole weight: 747.08 g/mol. Product ID: ACM1046146397. Alfa Chemistry ISO 9001:2015 Certified. | |
| Bst2B I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 60°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. C↑TCGTG GAGCA↓C. Activity: 5000-10000u.a./ml. Appearance: 10 X SE-buffer Y, BSA. Storage: -20°C. Form: Liquid. Source: Bacillus stearothermophilus 2B. Pack: 10 mM Tris-HCl (pH 7.5); 200 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 50% glycerol. Cat No: ET-1060RE. | |
| Bst2U I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 60°C in a total reaction volume of 50 μl. Applications: After 2-fold overdigestion with enzyme < 5% of dna fragments can be ligated. Group: Restriction Enzymes. Purity: 1000U; 5000U. CC↑WGG GGW↓CC. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer G, BSA. Storage: -20°C. Form: Liquid. Source: Bacillus stearothermophilus 2U. Pack: 10 mM Tris-HCl (pH 7.5); 200 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1061RE. | |
| Bst4C I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 65°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme ~50% of dna fragments can be ligated. Group: Restriction Enzymes. Purity: 500 U; 2500U. ACN↑GT TG↓NCA. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: Bacillus stearothermophilus 4C. Pack: 10 mM Tris-HCl (pH 7.5); 200 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1062RE. | |
| Bst6 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 65°C in a total reaction volume of 50 μl. Applications: After 2-fold overdigestion with enzyme 80% of dna fragments can be ligated. of these 80% can be recut. Group: Restriction Enzymes. Purity: 200U; 1000U. CTCTTC(N)1↑ GAGAAG(N)4&darr. Activity: 1000-5000u.a./ml. Appearance: 10 X SE-buffer Y, BSA. Storage: -20°C. Storage at -70°C is recommended for periods longer than 30 days. Form: Liquid. Source: Bacillus stearothermophilus 6. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1063RE. | |
| BstAC I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. GR↑CGYC CYGC↓RG. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer W. Storage: -20°C. Form: Liquid. Source: Bacillus stearothermophilus AC. Pack: 10 mM Tris-HCl (pH 7.5); 200 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1064RE. | |
| BstAF I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 55°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme ~40% of the dna fragments can be ligated and 95% of these can be recut. in the presence of 10% peg ligation is better. Group: Restriction Enzymes. Purity: 1000U; 5000U. C↑TTAAG GAATT↓C. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer W. Storage: -20°C. Form: Liquid. Source: Bacillus stearothermophilus AF. Pack: 10 mM Tris-HCl (pH 7.5); 200 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1065RE. | |
| BstAP I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 60°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. GCANNNN↑NTGC CGTN↓NNNNACG. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer W. Storage: -20°C. Form: Liquid. Source: Bacillus stearothermophilus AP. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0,1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; and 50% glycerol. Cat No: ET-1066RE. | |
| BstAU I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme > 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. T↑GTACA ACATG↓T. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer W. Storage: -20°C. Form: Liquid. Source: Bacillus stearothermophillus AU. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA; 50% glycerol. Cat No: ET-1067RE. | |
| BstBA I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 65°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. YAC↑GTR RTG↓CAY. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer W, BSA. Storage: -20°C. Form: Liquid. Source: Bacillus stearothermophilus BA. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 10 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1068RE. | |
| BstC8I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 55°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme more than 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. GCN↑NGC CGN↓NCG. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: Bacillus stearothermophilus C8. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1069RE. | |
| BstDE I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 60°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. C↑TNAG GANT↓C. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer G. Storage: -20°C. Form: Liquid. Source: Bacillus stearothermophilus DE. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 50% glycerol. Cat No: ET-1070RE. | |
| BstDS I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 65°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. C↑CRYGG GGYRC↓C. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: Bacillus stearothermophilus DS. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1071RE. | |
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