A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Cholera Autoinducer 1: (3S)-3-Hydroxy-4-tridecanone is an extracellular quorum-sensing molecule which is responsible for the virulence production factor and biofilm development of Vibrio cholerae. Group: Biochemicals. Grades: Highly Purified. CAS No. 1004296-82-5. Pack Sizes: 5mg, 10mg. Molecular Formula: C13H26O2, Molecular Weight: 214.34. US Biological Life Sciences.
recombinant, expressed in HEK 293 cells, subunit A free. Group: Fluorescence/luminescence spectroscopy.
Cholera toxin B subunit, from vibrio cholerae
Cholera toxin B subunit, from vibrio cholerae (CTB, from vibrio cholerae) is non-toxic to cells and possesses no intrinsic adenylate cyclase activity. Cholera toxin B subunit, from vibrio cholerae attaches to cells by binding to ganglioside GM1.8 CTB has been shown to be a good label for microglial cells (due to the enrichment of ganglioside GM1 on their cell surface), but not for oligodendrocytes or astrocytes. Cholera toxin B subunit, from vibrio cholerae has been reported to be an excellent tracer for the study of axonal transport using immunohistochemical methods. Cholera toxin B subunit, from vibrio cholerae has been widely used as a marker of membrane lipid rafts [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: CTB, from vibrio cholerae. CAS No. 131096-89-4. Pack Sizes: 500 μg; 1 mg. Product ID: HY-P3394.
This enzyme, found in several bacterial pathogens, is involved in degradation of the host cholesterol. It catalyses the hydroxylation of the C-26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate, initiating the degradation of the alkyl side-chain of cholesterol. The products are exclusively in the (25R) conformation. The enzyme also accepts cholesterol as a substrate. cf. EC 1.14.13.141, cholest-4-en-3-one 26-monooxygenase. The enzyme can receive electrons from ferredoxin reductase in vitro, its natural electron donor is not known yet. Group: Enzymes. Synonyms: CYP142. Enzyme Commission Number: EC 1.14.13.221. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0824; cholest-4-en-3-one 26-monooxygenase [(25R)-3-oxocholest-4-en-26-oate forming]; EC 1.14.13.221; CYP142. Cat No: EXWM-0824.
This enzyme, found in several bacterial pathogens, is involved in degradation of the host's cholesterol. It catalyses the hydroxylation of the C-26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate, initiating the degradation of the alkyl side-chain of cholesterol. The products are exclusively in the (25S) configuration. It is a two-component system consisting of a P-450 (heme thiolate) oxygenase (Cyp125) and a ferredoxin reductase (most likely KshB, which is also a part of EC 1.14.13.142, 3-ketosteroid 9α-monooxygenase). The enzyme also accepts cholesterol as a substrate. cf. EC 1.14.13.221, cholest-4-en-3-one 27-monooxygenase. Group: Enzymes. Synonyms: CYP125; CYP125A1; cholest-4-en-3-one 27-monooxygenase (misleading); cholest-4-en-3-one,NADH:oxygen oxidoreductase (26-hydroxyl. Enzyme Commission Number: EC 1.14.13.141. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0741; cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming]; EC 1.14.13.141; CYP125; CYP125A1; cholest-4-en-3-one 27-monooxygenase (misleading); cholest-4-en-3-one,NADH:oxygen oxidoreductase (26-hydroxylating); cholest-4-en-3-one 26-monooxygenase (ambiguous). Cat No: EXWM-0741.
Cholest-5-en-3beta-yl p-butoxybenzoate
Cholest-5-en-3beta-yl p-butoxybenzoate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: EINECS 255-394-9, CID6451742, Cholest-5-en-3beta-yl p-butoxybenzoate, BAS 00124352, 41484-52-0. Product Category: Heterocyclic Organic Compound. CAS No. 41484-52-0. Molecular formula: C38H58O3. Mole weight: 562.865320 [g/mol]. Purity: 0.96. IUPACName: [(3S,10R,13R,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] 4-butoxybenzoate. Canonical SMILES: CCCCOC1=CC=C(C=C1)C(=O)OC2CCC3(C4CCC5(C(C4CC=C3C2)CCC5C(C)CCCC(C)C)C)C. ECNumber: 255-394-9. Product ID: ACM41484520. Alfa Chemistry ISO 9001:2015 Certified.
Cholest-5-en-3beta-yl p-ethoxybenzoate
Cholest-5-en-3beta-yl p-ethoxybenzoate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: EINECS 255-393-3, CID6451741, Cholest-5-en-3beta-yl p-ethoxybenzoate, BAS 00124357, 41484-50-8. Product Category: Heterocyclic Organic Compound. CAS No. 41484-50-8. Molecular formula: C36H54O3. Mole weight: 534.812160 [g/mol]. Purity: 0.96. IUPACName: [(3S,10R,13R,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] 4-ethoxybenzoate. Canonical SMILES: CCOC1=CC=C(C=C1)C(=O)OC2CCC3(C4CCC5(C(C4CC=C3C2)CCC5C(C)CCCC(C)C)C)C. ECNumber: 255-393-3. Product ID: ACM41484508. Alfa Chemistry ISO 9001:2015 Certified.
Cholest-5-en-3-ol is a powerful substance that functions to combat hypercholesterolemia and various lipid disorders. Using innovative technology, it works to inhibit cholesterol synthesis in the liver, leading to the reduction of overall blood cholesterol levels. Due to its notable and demonstrated effectiveness, it is highly regarded and widely employed within the biopharmaceutical industry in the treatment of cardiovascular diseases. CAS No. 143723-64-2.
Cholest-5-en-3-ol (3b)-, 3-(carbonochloridate)
Cholest-5-en-3-ol (3b)-, 3-(carbonochloridate). Group: Biochemicals. Grades: Highly Purified. CAS No. 7144-8-3. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C28H45ClO2. US Biological Life Sciences.
Worldwide
Cholest-5-en-3-ol, 3-CEphosphoramidite
Cholest-5-en-3-ol, 3-CEphosphoramidite, a versatile phosphoramidite reagent, is vital for modifying RNA and DNA analogs. Its immense value lies in its ability to assist in the treatment of varied afflictions including cancer, HIV, and genetic defects, making it a pivotal cog in the biomedical industry. Respected chemical suppliers globally procure and make it available. CAS No. 143723-63-1.
cholest-5-ene-3β,7α-diol 3β-dehydrogenase
Highly specific for 3β-hydroxy-C27-steroids with Δ5-double bond. Group: Enzymes. Synonyms: 3β-hydroxy-Δ5-C27-steroid oxidoreductase. Enzyme Commission Number: EC 1.1.1.181. CAS No. 56626-16-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0084; cholest-5-ene-3β,7α-diol 3β-dehydrogenase; EC 1.1.1.181; 56626-16-5; 3β-hydroxy-Δ5-C27-steroid oxidoreductase. Cat No: EXWM-0084.
A metabolite of Cholesterol. Group: Biochemicals. Alternative Names: 4,6-Cholestadien-3-one; NSC 119073. Grades: Highly Purified. CAS No. 566-93-8. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Cholestan-3β,5α-diol
Cholestan-3β,5α-diol. Uses: Designed for use in research and industrial production. Product Category: Steroidal Compounds. CAS No. 3347-60-2. Molecular formula: C27H48O2. Mole weight: 404.67. Purity: 0.95. Product ID: ACM3347602. Alfa Chemistry ISO 9001:2015 Certified.
Cholestan-5α,6β-diol
Cholestan-5α,6β-diol. Uses: Designed for use in research and industrial production. Product Category: Steroidal Compounds. CAS No. 566-31-4. Molecular formula: C27H48O2. Mole weight: 404.67. Purity: 0.95. Product ID: ACM566314. Alfa Chemistry ISO 9001:2015 Certified.
Cholestan-5α-ol-3,6-dione
Cholestan-5α-ol-3,6-dione. Uses: Designed for use in research and industrial production. Product Category: Steroidal Compounds. CAS No. 20281-70-3. Molecular formula: C27H44O3. Mole weight: 416.64. Purity: 0.95. Product ID: ACM20281703. Alfa Chemistry ISO 9001:2015 Certified.
Cholestan-5β,6β-epoxy-3β-ol
Cholestan-5β,6β-epoxy-3β-ol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5beta,6beta-Epoxycholestanol; CHOLESTEROL-5BETA,6BETA-EPOXIDE; 5,6beta-epoxy-5beta-cholestan-3beta-ol; 5BETA,6BETA-EPOXYCHOLESTAN-3BETA-OL; cholestanol,5ß,6ß-epo; cholesterol-5B,6B-epoxide; cholesterolbeta-epoxide. Product Category: Steroidal Compounds. CAS No. 4025-59-6. Molecular formula: C27H46O2. Mole weight: 402.65. Purity: 0.95. IUPACName: 5,6β-epoxy-5β-cholestan-3β-ol. Density: 1.04g/cm³. Product ID: ACM4025596. Alfa Chemistry ISO 9001:2015 Certified.
Cholestane-3b,5a,6b-triol
Cholestane-3b,5a,6b-triol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3beta,5alpha,6beta-Trihydroxycholestane; 3beta,5alpha,6beta-Cholestanetriol; Cholestane-3beta,5alpha,6beta-triol; Cholesta-3beta,5alpha,6beta-triol; cholestanetriol; 5alpha,6beta-Dihydroxycholestanol; 5alpha-cholestane-3beta,5,6beta-triol; (3S,5R,6R,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,3,4,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-3,5,6-triol. Product Category: Steroidal Compounds. CAS No. 1253-84-5. Molecular formula: C27H48O3. Mole weight: 420.68. Purity: 0.95. IUPACName: (3S,5R,6R,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,3,4,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-3,5,6-triol. Canonical SMILES: CC(C)CCCC(C)C1CCC2C1(CCC3C2CC(C4(C3(CCC(C4)O)C)O)O)C. Density: 1.065g/cm³. Product ID: ACM1253845. Alfa Chemistry ISO 9001:2015 Certified.
cholestanetriol 26-monooxygenase
This mitochondrial cytochrome P-450 enzyme requires adrenodoxin. It catalyses the first three sterol side chain oxidations in bile acid biosynthesis via the neutral (classic) pathway. Can also act on cholesterol, cholest-5-ene-3β,7α-diol, 7α-hydroxycholest-4-en-3-one, and 5β-cholestane-3α,7α-diol. The enzyme can also hydroxylate cholesterol at positions 24 and 25. The initial source of the electrons is NADPH, which transfers the electrons to the adrenodoxin via EC 1.18.1.6, adrenodoxin-NADP+ reductase. Group: Enzymes. Synonyms: 5β-cholestane-3α,7α,12α-triol 26-hydroxylase; 5β-cholestane-3α,7α,12α-triol hydroxylase; cholestanetriol 26-hydroxylase; sterol 27-hydroxylase; sterol 26-hydroxylase; cholesterol 27-hydroxyla. Enzyme Commission Number: EC 1.14.15.15. CAS No. 52227-77-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0940; cholestanetriol 26-monooxygenase; EC 1.14.15.15; 52227-77-7; 5β-cholestane-3α,7α,12α-triol 26-hydroxylase; 5β-cholestane-3α,7α,12α-triol hydroxylase; cholestanetriol 26-hydroxylase; sterol 27-hydroxylase; sterol 26-hydroxylase; cholesterol 27-hydroxylase; CYP27A; CYP27A1; cytochrome P450 27A1'. Cat No: EXWM-0940.
This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. This enzyme participates in biosynthesis of steroids. Group: Enzymes. Enzyme Commission Number: EC 5.3.3.5. CAS No. 52410-46-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5502; cholestenol Δ-isomerase; EC 5.3.3.5; 52410-46-5. Cat No: EXWM-5502.
Cholesterol
Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins [1] [2]. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist [3]. Uses: Scientific research. Group: Natural products. CAS No. 57-88-5. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-N0322.
Cholesterol is a natural waxy substance that is found in human skin and is also commonly used in cosmetics and skincare products. In cosmetics, cholesterol is used as a moisturizer and emollient to help soften and smooth the skin, as well as to improve the appearance of fine lines and wrinkles. It is also believed to help strengthen the skin's barrier function and protect against environmental damage. The chemical formula of cholesterol is C27H46O, and it typically appears as a white or off-white powder or solid. It is also available in liquid form, often in combination with other ingredients. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3β-Hydroxycholest-5-ene. Product Category: Cholesteryl Esters. Appearance: White powder. CAS No. 57-88-5. Molecular formula: C27H46O. Mole weight: 386.66. Purity: 0.98. IUPACName: (3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol. Canonical SMILES: CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C. Density: 1.06 g/cm³. Product ID: ACM57885. Alfa Chemistry ISO 9001:2015 Certified.
Cholesterol
500g Pack Size. Group: Biochemicals. Formula: C27H46O. CAS No. 57-88-5. Prepack ID 13575167-500g. Molecular Weight 386.65. See USA prepack pricing.
Cholesterol
100g Pack Size. Group: Biochemicals. Formula: C27H46O. CAS No. 57-88-5. Prepack ID 13575167-100g. Molecular Weight 386.65. See USA prepack pricing.
Cholesterol
Cholesterol occurs as white or faintly yellow, almost odorless, pearly leaflets, needles, powder, or granules. On prolonged exposure to light and air, cholesterol acquires a yellow to tan color. Synonyms: Cholesterin; cholesterolum. CAS No. 57-88-5. Product ID: PE-0519. Molecular formula: C27H46O. Mole weight: 386.67. Category: Emollient; Emulsifying Agents. Product Keywords: Excipients for Liquid Dosage Form; Emulsifier Excipients; PE-0519; Cholesterol; Emollient; Emulsifying Agents; C27H46O; 57-88-5. UNII: 97C5T2UQ7J. Chemical Name: Cholest-5-en-3β-ol. Grade: Pharmceutical Excipients. Administration route: Injections; ophthalmic, topical, and vaginal. Dosage Form: Injections; ophthalmic, topical, and vaginal preparations. Stability and Storage Conditions: Cholesterol is stable and should be stored in a well-closed container, protected from light. Source and Preparation: The commercial material is normally obtained from the spinal cord of cattle by extraction with petroleum ethers, but it may also be obtained from wool fat. Purification is normally accomplished by repeated bromination. Cholesterol may also be produced by entirely synthetic means. Cholesterol produced from animal organs will always contain cholestanol and other saturated sterols. Applications: Cholesterol is used in cosmetics and topical pharmaceutical formulations at concentrations of 0.3-5.0% w/w as an emulsifying agent. It imparts water-absorbi
Cholesterol - Product ID: NST-10-135. Category: Sterols. Alternative Names: (-)-Cholesterol, Cholesteryl alcohol, Dythol, Lidinit, Marine Cholesterol, Provitamin D. Purity: 98%. Test method: HPLC. CAS No. 57-88-5. Pack Sizes: 50g, 100g, 250g, 500g. Appearance: White to beige coloured Powder. Molecular formula: C27H46O. Mole weight: 386.66. Storage: +2 +8 °C.
Cholesterol-13C2
Cholesterol- 13 C 2 is the 13 C labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins [1] [2]. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist [3]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 78887-48-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N0322S5.
Cholesterol-2,2,3,4,4,6-d6
Cholesterol-2,2,3,4,4,6-d6. Group: Biochemicals. Grades: Highly Purified. CAS No. 92543-08-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C27D6H40O. US Biological Life Sciences.
Worldwide
Cholesterol-2,2,3,4,4,6-d6
97 atom % D, 98% (CP). Group: Fluorescence/luminescence spectroscopy.
Cholesterol-23,24,25,26,27-13C5
?99 atom % 13C, ?98% (CP). Group: Fluorescence/luminescence spectroscopy.
Cholesterol-2,3,4-13C3
99 atom % 13C, 98% (CP). Group: Fluorescence/luminescence spectroscopy.
cholesterol 24-hydroxylase
A P-450 heme-thiolate protein. The enzyme can also produce 25-hydroxycholesterol. In addition, it can further hydroxylate the product to 24,25-dihydroxycholesterol and 24,27-dihydroxycholesterol. This reaction is the first step in the enzymic degradation of cholesterol in the brain as hydroxycholesterol can pass the blood-brain barrier whereas cholesterol cannot. The direct electron donor to the enzyme is EC 1.6.2.4, NADPH-hemoprotein reductase. Group: Enzymes. Synonyms: cholesterol 24-monooxygenase; CYP46; CYP46A1; cholesterol 24S-hydroxylase; cytochrome P450 46A1. Enzyme Commission Number: EC 1.14.14.25. CAS No. 50812-30-1, 213327-78-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0922; cholesterol 24-hydroxylase; EC 1.14.14.25; 50812-30-1, 213327-78-7; cholesterol 24-monooxygenase; CYP46; CYP46A1; cholesterol 24S-hydroxylase; cytochrome P450 46A1. Cat No: EXWM-0922.
Cholesterol 24-hydroxylase-IN-1
Cholesterol 24-hydroxylase-IN-1 (compound 17) is a potent, orally active, and highly selective cholesterol 24-hydroxylase (CH24H or CYP46A1) inhibitor ( IC 50 =8.5 nM). Cholesterol 24-hydroxylase-IN-1 can cross blood-brain barrier [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1613480-70-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144309.
cholesterol 25-hydroxylase
Unlike most other sterol hydroxylases, this enzyme is not a cytochrome P-450. Instead, it uses diiron cofactors to catalyse the hydroxylation of hydrophobic substrates. The diiron cofactor can be either Fe-O-Fe or Fe-OH-Fe and is bound to the enzyme through interactions with clustered histidine or glutamate residues. In cell cultures, this enzyme down-regulates cholesterol synthesis and the processing of sterol regulatory element binding proteins (SREBPs). Group: Enzymes. Synonyms: cholesterol 25-monooxygenase. Enzyme Commission Number: EC 1.14.99.38. CAS No. 60202-07-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1049; cholesterol 25-hydroxylase; EC 1.14.99.38; 60202-07-5; cholesterol 25-monooxygenase. Cat No: EXWM-1049.
Cholesterol-25-Hydroxylase, Human (CH25H)
Cholesterol-25-Hydroxylase (CH25H) is an intronless gene that is involved in cholesterol and lipid metabolism. The encoded protein is a membrane protein and contains clusters of histidine residues essential for catalytic activity. Unlike most other sterol hydroxylases, this enzyme is a member of a small family of enzymes that utilize diiron cofactors to catalyze the hydroxylation of hydrophobic substrates. Group: Molecular Biology. Pack Sizes: 10ug, 50ug, 100ug. US Biological Life Sciences.
Worldwide
Cholesterol 3-Acetate-d7
Isotope labelled Cholesterol 3-Acetate-d7 is an derivative of Cholesterol (C432501), a major component of all biological membranes. Group: Biochemicals. Alternative Names: (-)-Cholesteryl Acetate-d7; (3 β)-Cholest-5-en-3-ol Acetate-d7; 3-Cholesteryl Acetate-d7; 3 β-Acetoxycholest-5-ene-d7; Cholest-5-en-3 β-ol Acetate-d7; Cholest-5-en-3 β-yl Acetate-d7; Cholesterin Acetate-d7; Cholesterol 3-Acetate-d7; Cholesterol 3 β-Acetate-d7; Cholesteryl Acetate-d7; NSC 8799. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Cholesterol 3-sulfate sodium salt
Cholesterol 3-sulfate sodium salt. Group: Biochemicals. Alternative Names: (3b)-Cholest-5-en-3-ol 3-(hydrogen sulfate) sodium salt. Grades: Highly Purified. CAS No. 2864-50-8. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C27H45NaO4S. US Biological Life Sciences.
Worldwide
Cholesterol-3-sulfate, Sodium Salt (Cholesterol, Hydrogen Sulfate)
Cholesterol-3-sulfate, Sodium Salt (Cholesterol, Hydrogen Sulfate). Group: Biochemicals. Alternative Names: Cholesterol, Hydrogen Sulfate. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
Cholesterol-4-13C
Cholesterol-4-13C. Uses: Designed for use in research and industrial production. Additional or Alternative Names: [4-13C]Cholest-5-en-3β-ol. Product Category: Heterocyclic Organic Compound. CAS No. 99964-70-2. Molecular formula: 13CC26H46O. Mole weight: 387.67. Purity: 99 atom % 13C. Density: 1.070 g/mL at 25 °C. Product ID: ACM99964702. Alfa Chemistry ISO 9001:2015 Certified.
The enzyme appears to work equally well with either epoxide as substrate. The product is a competitive inhibitor of the reaction. In vertebrates, five epoxide-hydrolase enzymes have been identified to date: EC 3.3.2.6 (leukotriene-A4 hydrolase), EC 3.3.2.7 (hepoxilin-epoxide hydrolase), EC 3.3.2.9 (microsomal epoxide hydrolase), EC 3.3.2.10 (soluble epoxide hydrolase) and EC 3.3.2.11 (cholesterol 5,6-oxide hydrolase). Group: Enzymes. Synonyms: cholesterol-epoxide hydrolase; ChEH. Enzyme Commission Number: EC 3.3.2.11. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3996; cholesterol-5,6-oxide hydrolase; EC 3.3.2.11; cholesterol-epoxide hydrolase; ChEH. Cat No: EXWM-3996.
Cholesterol 5α,6α-epoxide
Cholesterol-5α,6α-epoxide is an epoxide derivative of cholesterol formed by the enzymatic oxidation of cholesterol in the liver and other tissues. Cholesterol-5α,6α-epoxide has unique chemical properties that make it an important intermediate in the biosynthesis of bile acids, which play a key role in the digestion and absorption of dietary fats. It also has a potential physiological role in regulating cholesterol metabolism and transport, although its biological function is not fully understood. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 5α,6α-Epoxycholesterol. CAS No. 1250-95-9. Pack Sizes: 25 mg; 50 mg. Product ID: HY-133971.
Cholesterol-5α,6α-epoxide
Cholesterol-5α,6α-epoxide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5,6alpha-epoxy-5alpha-cholestan-3beta-ol; cholestanol; Cholesterol epoxide; Cholesterol-5α,6α-epoxide; Epoxycholesterol; Cholesterol-5alpha,6alpha-epoxide. Product Category: Steroidal Compounds. CAS No. 1250-95-9. Molecular formula: C27H46O2. Mole weight: 402.65. Purity: 0.95. IUPACName: 5,6α-epoxy-5α-cholestan-3β-ol. Canonical SMILES: CC(C)CCCC(C)C1CCC2C1(CCC3C2CC4C5(C3(CCC(C5)O)C)O4)C. Density: 1.04g/cm³. ECNumber: 215-007-6. Product ID: ACM1250959. Alfa Chemistry ISO 9001:2015 Certified.
cholesterol 7α-monooxygenase
A P-450 heme-thiolate liver protein that catalyses the first step in the biosynthesis of bile acids. The direct electron donor to the enzyme is EC 1.6.2.4, NADPH-hemoprotein reductase. Group: Enzymes. Synonyms: cholesterol 7α-hydroxylase; CYP7A1 (gene name). Enzyme Commission Number: EC 1.14.14.23. CAS No. 9037-53-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0920; cholesterol 7α-monooxygenase; EC 1.14.14.23; 9037-53-0; cholesterol 7α-hydroxylase; CYP7A1 (gene name). Cat No: EXWM-0920.
cholesterol 7-desaturase
The enzyme, characterized from several organisms including the worm Caenorhabditis elegans, the fly Drosophila melanogaster, and the ciliate Tetrahymena thermophila, is a Rieske oxygenase. In insects it participates in the the biosythesis of ecdysteroid hormones. The electrons are transferred from NAD(P)H via an electron transfer chain likely to include ferredoxin reductase and ferredoxin. The enzyme differs from regular desaturases, such as EC 1.14.19.20, 7-sterol 5(6)-desaturase, which are cytochrome b5-dependent and contain the three His-boxes that are typical to most desaturases. Group: Enzymes. Synonyms: nvd (gene name); daf-36 (gene name). Enzyme Commission Number: EC 1.14.19.21. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0984; cholesterol 7-desaturase; EC 1.14.19.21; nvd (gene name); daf-36 (gene name). Cat No: EXWM-0984.
Cholesterol (>99%) (stabilized with alpha-Tocopherol)
Cholesterol (>99%) (stabilized with alpha-Tocopherol). Group: Molecular Biology. Grades: Highly Purified. CAS No. 57-88-5. Pack Sizes: 1g, 5g. Molecular Formula: C27H46O. US Biological Life Sciences.
Worldwide
Cholesterol absorption inhibitor 1
Cholesterol absorption inhibitor 1 (compound 21) is a cholesterol absorption inhibitor that reduces liver cholesteryl ester [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 190595-65-4. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-45131.
Cholesterol β-D-glucoside is a derivative of cholesterol that contains β-D-glucose. It is formed from cholesterol and glucosylceramide by β-glucosidase 1. It is a lipid mediator in heat stress responses in animals, showing anti-ulcer effect. It activates heat shock transcription factor 1 (Hsf1) in response to heat shock, which increases the expression of heat shock protein 70 (Hsp70) in TIG-3 human fetal lung fibroblasts when used at a concentration of 10 μM. Synonyms: β-ChlGlc; Cholesteryl Glucoside; GluChol; Glucosyl Cholesterol; β-D-glucosyl cholesterol. Grades: ≥95%. CAS No. 7073-61-2. Molecular formula: C33H56O6. Mole weight: 548.79.
Cholesterol butyrate
Cholesterol butyrate. Group: Liquid crystal (lc) building blocks. Alternative Names: Cholesteryl N-Butyrate. CAS No. 521-13-1. Product ID: [(10R,13R)-10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] butanoate. Molecular formula: 456.8. Mole weight: C31H52O2. CKDZWMVGDHGMFR-IIPYNTGOSA-N. 99%+.
Bovine Cholesterol Concentrate is a concentrated cholesterol additive consisting mainly of bovine high density lipoproteins. The lipoproteins are substantially free of other serum proteins. Typical cholesterol concentrations are in the range of 6000 to 8000mg/dL. Group: Molecular Biology. Alternative Names: BCC; HDL; High Density Lipoprotein; HDL-C; HDL Concentrate; HDL Fraction; alpha-Lipoprotein. Grades: Molecular Biology Grade. CAS No. 57-88-5. Pack Sizes: 100mg, 1g. US Biological Life Sciences.
Worldwide
Cholesterol-d4
Labeled Cholesterol. Cholesterol is the principal sterol of the higher animals. Cholesterol was found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Cholesterol is the main constituent of gallstones. Group: Biochemicals. Alternative Names: Cholesterol-25,26,26,26-d4; (3 β)-. Grades: Highly Purified. CAS No. 956029-28-0. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Cholesterol-d6
Labeled Cholesterol. Cholesterol is the principal sterol of the higher animals. Cholesterol was found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Cholesterol is the main constituent of gallstones. Group: Biochemicals. Alternative Names: Cholesterol-2,2,3,4,4,6-d6; (3 β)-Cholest-5-en-3-ol-d6; (3 β)-. Grades: Highly Purified. CAS No. 92543-08-3. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Cholesterol-d6
Cholesterol-d 6 is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins [1] [2]. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist [3] [4]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 60816-17-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N0322S1.
Cholesterol-d7
Cholesterol-d 7 is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins [1] [2]. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist [3]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 83199-47-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0322S.