A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
CP 316819. Group: Biochemicals. Grades: Purified. CAS No. 186392-43-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CP 316819
CP 316819 has been found to be a glycogen phosphorylase inhibitor and could probably be used in the treatment for glycemic control in type 2 diabetes. Synonyms: CP 316819; CP316819; CP-316819; 5-Chloro-N-[(1S,2R)-2-hydroxy-3-(methoxymethylamino)-3-oxo-1-(phenylmethyl)propyl]-1H-indole-2-carboxamide. Grades: ≥98% by HPLC. CAS No. 186392-43-8. Molecular formula: C21H22ClN3O4. Mole weight: 415.87.
CP-316819
A novel glycogen phosphorylase inhibitor; potential treatment for glycemic control in type 2 diabetes. Group: Biochemicals. Alternative Names: 5-Chloro-N-[(1S,2R)-2-hydroxy-3-(methoxymethylamino)-3-oxo-1-(phenylmethyl)propyl]-1H-indole-2-carboxamide; GPi 819; CP 316 819. Grades: Highly Purified. CAS No. 186392-43-8. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CP-320626
CP-320626, a carboxamide derivative, is a potent glycogen phosphorylase inhibitor and a possible target for type 2 diabetes therapy. CP-320626 is also a potent inhibitor of human muscle GPa. Synonyms: 5-chloro-N-[(2S)-3-(4-fluorophenyl)-1-(4-hydroxypiperidin-1-yl)-1-oxopropan-2-yl]-1H-indole-2-carboxamide;CP-320626; CP320626; CP 320626. Grades: >98%. CAS No. 186430-23-9. Molecular formula: C23H23ClFN3O3. Mole weight: 443.90.
CP-331684
CP-331684 is a β3-adrenergic receptor agonist used as antidiabetic drug. Synonyms: CP-331684; CP331684; CP 331684; UNII-9EY0MGZ7F8. 2- [4- [2- [ [ (2R) -2- (6-aminopyridin-3-yl) -2-hydroxyethyl] amino] ethoxy] phenyl] acetic acid. Grades: >98%. CAS No. 207922-70-1. Molecular formula: C17H21N3O4. Mole weight: 331.37.
CP-335963
CP-335963. Group: Biochemicals. Alternative Names: 4-Chloro-6, 7-bis (2-methoxyethoxy) quinazoline; 4-Chloro-6, 7-di (2-methoxyethoxy) quinazoline; 6,7-Bis(2-methoxyethoxy)-4-chloroquinazoline; PF-508367. Grades: Highly Purified. CAS No. 183322-18-1. Pack Sizes: 10mg. Molecular Formula: C14H17ClN2O4, Molecular Weight: 312.75. US Biological Life Sciences.
Worldwide
CP 339818 hydrochloride
CP 339818 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 478341-55-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CP 339818 hydrochloride
CP 339818 hydrochloride is the hydrochloride salt form of CP 339818, a non-peptide KV1.3 channel antagonist that is more effective at blocking HCN1 than HCN4. Synonyms: 1-Pentanamine, N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-, hydrochloride (1:1); 1-Pentanamine, N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-, monohydrochloride; Cp 339818 monohydrochloride; N-[1-(Phenylmethyl)-4(1H)-quinolinylidene]-1-pentanamine hydrochloride; (1-Benzyl-1H-quinolin-4-ylidene)-pentyl-amine hydrochloride; 1-Benzyl-N-pentylquinolin-4(1H)-imine hydrochloride; N-(1-Benzylquinolin-4(1H)-ylidene)pentan-1-amine hydrochloride. Grades: ≥99% by HPLC. CAS No. 478341-55-8. Molecular formula: C21H24N2.HCl. Mole weight: 340.89.
CP 339818 hydrochloride
CP 339818 hydrochloride is a nonpeptide and selective Kv1.3 ( IC 50 value of ~200 nM) and Kv1.4 channels blocker. CP 339818 hydrochloride is a significantly less potent blocker of Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2. CP 339818 hydrochloride potently blocks the C-type inactivated conformation of Kv1.3 and suppresses T cell activation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 478341-55-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108574.
CP 346086
CP 346086 is a potent microsomal triglyceride transfer protein (MTP, MTTP) inhibitor. It reduces LDL cholesterol and triglycerides, and can be used for the treatment of obesity. Uses: The treatment of obesity. Synonyms: CP 346086; CP346086; CP-346086; N-[1,2,3,4-Tetrahydro-2-(1H-1,2,4-triazol-5-ylmethyl)-6-isoquinolinyl]-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamide. Grades: 99%. CAS No. 186390-48-7. Molecular formula: C26H22F3N5O. Mole weight: 477.48.
CP 346086 Dihydrate
CP-346086 is microsomal triglyceride transfer protein (MTP, MTTP) inhibitor for treatment of obesity. Group: Biochemicals. Alternative Names: N-[1,2,3,4-Tetrahydro-2-(1H-1,2,4-triazol-5-ylmethyl)-6-isoquinolinyl]-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamide Dihydrate. Grades: Highly Purified. CAS No. 186390-48-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CP-35587
CP-35587 is resistant to gram-positive cocci, but it has no effect on penicillin-resistant Staphylococcus aureus and is active against gram-negative bacteria. Synonyms: Benzeneacetamide, alpha-amino-N-(3,3-dimethyl-7-oxo-2-(1H-tetrazol-5-yl)-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-4-hydroxy-, (2S-(2alpha,5alpha,6beta))-. CAS No. 57089-17-5. Molecular formula: C16H19N7O3S. Mole weight: 389.43.
CP-376395 HCl
CP-376395 HCl is a potent and selective CRF1 receptor antagonist with Ki values of 12 and >10000 nM for CRF1 and CRF2 receptors respectively. It attenuates CRF-induced activation of the HPA axis in vivo. Synonyms: CP376395 HCl; CP 376395 HCl; 2-(Mesityloxy)-3,6-dimethyl-N-(pentan-3-yl)pyridin-4-amine hydrochloride;3,6-Dimethyl-N-pentan-3-yl-2-(2,4,6-trimethylphenoxy)pyridin-4-amine hydrochloride. Grades: >98 %. CAS No. 1013933-37-3. Molecular formula: C21H31ClN2O. Mole weight: 362.94.
CP 376395 hydrochloride
CP 376395 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1013933-37-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CP-394531
CP-394531 is an effective Glucocorticoid receptor agonist and probably has steroid-like anti-inflammatory properties with anti-GR and anti-obesity activity in animal models. Uses: Glucocorticoid receptor antagonists. Synonyms: CP-394531; CP 394531; CP394531; UNII-227D9ED2SI. (2R,4aS,10aR)-4a-benzyl-2-(chloroethynyl)-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-2,7-diol. Grades: ≥95%. CAS No. 305822-63-3. Molecular formula: C23H23ClO2. Mole weight: 366.14.
CP-409092
CP-409092 is a GABA(A) partial agonist developed for the treatment of General Anxiety Disorder (GAD) and presents an interesting phenomenon of human pharmacokinetic predictions. In vitro, CP-409092 was abroadly metabolized in rat and human systems predominantly to acid metabolite formed by oxidative deamination of the N-methyl group of CP-409092 mediated by MAO-A (as deduced from inhibition experiments). Synonyms: N-[4-(methylaminomethyl)phenyl]-4-oxo-1,5,6,7-tetrahydroindole-3-carboxamide; 4-oxo-4,5,6,7-tetrahydro-1H-indole-3-carboxylic acid (4-methylaminomethylphenyl)amide; CP 409,092; CP 409092; CP-409,092; CP-409092; CP409,092; CP409092. Grades: >98%. CAS No. 194098-25-4. Molecular formula: C17H19N3O2. Mole weight: 297.35.
CP 412065
It is originally isolated from Hericium ramosum CL 24240. CP 412065 selectively inhibited κ-opioid receptor binding with IC50 > 200 μnmol/L. Synonyms: Antibiotic CP 412065. Molecular formula: C25H34O6. Mole weight: 430.53.
CP 424174
CP 424174 has been found to be an inhibitor of stimulus-coupled IL-1β post-translational processing. Synonyms: CP-424174; CP 424174; CP424174; CP-424,174; CP 424,174; CP424,174; N-[[[4-Chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)benzenesulfonamide. Grades: ≥98% by HPLC. CAS No. 210825-31-3. Molecular formula: C22H29ClN2O4S. Mole weight: 452.99.
CP-432
CP-432 is an EP4 prostaglandin agonist , potential useful for the treatment of glaucoma and ocular hypertension. Uses: An ep4 prostaglandin agonist. Synonyms: CP-432; CP 432; CP432; CP-734432; CP 734432; CP734432. 5-(3-((2S)-2-((3R)-3-hydroxy-4-(3-(trifluoromethyl)phenyl)butyl)-5-oxo-1-pyrrolidinyl)propyl)-2-Thiophenecarboxylic acid. Grades: ≥95%. CAS No. 431990-08-8. Molecular formula: C23H26F3NO4S. Mole weight: 469.52.
CP-456773 sodium
CP-456773, also known as MCC950 and CRID3, is a potent, orally bioavailable NLRP3 inflammasome inhibitor and inhibits IL-1β (IC50 = 7.2 nM), IL-1α (IC50 = 12-18 nM) and IL-18 (IC50 = 10.3 nM) production for the treatment of inflammatory diseases. Synonyms: sodium ((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)((4-(2-hydroxypropan-2-yl)furan-2-yl)sulfonyl)amide; MCC950; MCC 950; MCC-950; CP-45677; CP45677; CP 45677; CRID-3; CRID3; CRID 3; CP-456773 sodium salt; CP 456773 sodium salt; CP456773 sodium salt; Cytokine release inhibitory drug 3. CAS No. 256373-96-3. Molecular formula: C20H24N2NaO5S. Mole weight: 427.46.
CP-457677
CP-457677, also called as TX006169, is a JNK inhibitor. Synonyms: 2-(4-fluorophenoxy)-N-[[4-(2-hydroxypropan-2-yl)phenyl]methyl]pyridine-3-carboxamide; CP-457677; CP457677; CP 457677; UNII-5A83419M4U. Grades: >98%. CAS No. 214535-77-0. Molecular formula: C22H21FN2O3. Mole weight: 380.41.
CP-457920
CP-457920, also called as NGD 971, is a selective α5 GABAA receptor inverse agonist (Ki of ~ 1 ng/mL). CP-457920 was progressed into clinical studies for the treatment of Vascular dementia but discontinued. Synonyms: N-benzyl-6-ethoxy-4-oxo-1H-1,5-naphthyridine-3-carboxamide; CP-457920; CP457920; CP 457920; UNII-13BME2F602; CP-457,920. Grades: >98%. CAS No. 220860-50-4. Molecular formula: C18H17N3O3. Mole weight: 323.35.
CP 461
CP 461, belonging to a class of novel proapoptotic drugs with antineoplastic effect, specifically inhibit cyclic GMP phosphodiesterases but not cyclooxygenase-1 or -2. Synonyms: CP 461; CP-461; CP461; OSI 461; UNII-68OJX9I7DT. N-benzyl-2-[6-fluoro-2-methyl-3-(pyridin-4-ylmethylidene)inden-1-yl]acetamide;hydrochloride; CAS: 227619-92-3 (CP-461 free base). Grades: >98%. CAS No. 227619-96-7. Molecular formula: C25H22ClFN2O. Mole weight: 420.91.
CP-461 free base
CP 461, belonging to a class of novel proapoptotic drugs with antineoplastic effect, specifically inhibit cyclic GMP phosphodiesterases but not cyclooxygenase-1 or -2. Synonyms: CP-461 free base; CP 461 free base; CP461 free base; N-benzyl-2-[(3Z)-6-fluoro-2-methyl-3-(pyridin-4-ylmethylidene)inden-1-yl]acetamide; UNII-824ZMS3BGL; OSI-461 free base. Grades: >98%. CAS No. 227619-92-3. Molecular formula: C25H21FN2O. Mole weight: 384.45.
CP 465022
CP 465022, with anticonvulsant activity, is a potent, brain penetrant, orally active and selective noncompetitive AMPA receptor antagonist (IC50 = 25 nM in rat cortical neurons). CP 465022 provides neuroprotective efficacy after cerebral ischemia on the basis of the activity in experimental ischemia models. Synonyms: 3-(2-chlorophenyl)-2-[2-[6-(diethylaminomethyl)pyridin-2-yl]ethenyl]-6-fluoroquinazolin-4-one; CP-465022; CP 465022; CP465022; UNII-4582JTR93Y. Grades: >99 %. CAS No. 199655-36-2. Molecular formula: C26H24ClFN4O. Mole weight: 499.41.
CP-465022
CP-465022 is a potent, and selective noncompetitive AMPA receptor antagonist with anticonvulsant activity. CP-465022 is against Kainate-induced response with an IC 50 of 25 nM in rat cortical neurons. CP-465022 provides a new tool to investigate the role of AMPA receptors in physiological and pathophysiological processes [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 199655-36-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18663.
CP 465022 hydrochloride
CP 465022 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 199655-36-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
CP 46665 is Immunomodulator. But it is lack of therapeutic activity in rodent tumors and human non-seminomatous germ cell tumors growing in nude mice. Uses: Anti-tumor. Synonyms: CP 46665; CP46665; CP-46665; CP-46,665. 4-Aminomethyl-1-(2,3-bis(decyloxy)propyl)-4-phenylpiperidine. Grades: 98%. CAS No. 72618-10-1. Molecular formula: C35H66Cl2N2O2. Mole weight: 617.82.
CP-466722
CP-466722 is a potent and reversible ATM inhibitor, does not affect ATR and inhibits PI3K or PIKK family members in cells. Synonyms: CP-466722; CP 466722; CP466722. Grades: >98%. CAS No. 1080622-86-1. Molecular formula: C17H15N7O2. Mole weight: 349.35.
CP-467688
CP-467688 is a microsomal triglyceride transfer protein inhibitor used in atherosclerosis therapy. Synonyms: methyl N-[2-[6-[[2-[4- (trifluoromethyl) phenyl]benzoyl]amino]-3, 4-dihydro-1H-isoquinolin-2-yl]ethyl]carbamate; hydrochloride; 909576-25-6 (CP-467688); CP 467688; CP467688; 208590-81-2 (CP-467688 free base). Grades: >98%. CAS No. 208590-81-2. Molecular formula: C27H27ClF3N3O3. Mole weight: 533.97.
CP 471474
CP 471474 a broad spectrum Matrix Metalloprotease inhibitor with sub-nanomolar affinity for MMP-2 and 13 among MMPs (IC50: 1170, 0.7, 16, 13, 0.9 for MMP-1, MMP-2, MMP-3, MMP-9, and MMP-13 respectively). Synonyms: CP-471474; CP 471474; CP471474; UNII-96U47H947L; 2-[[4-(4-fluorophenoxy)phenyl]sulfonylamino]-N-hydroxy-2-methylpropanamide; CP 471474; CP-471474; 210755-45-6; CHEMBL323612. Grades: >97 %. CAS No. 210755-45-6. Molecular formula: C16H17FN2O5S. Mole weight: 368.38.
CP-471474
A broad spectrum inhibitor of matrix metalloproteinases that attenuates early left ventricular dilation after experimental myocardial infarction in mice. Studies show that it also inhibits cigarette smoke-induced lung inflammation and the progression of emphysema in guinea pig models. Group: Biochemicals. Alternative Names: 2-[[[4- (4-Fluorophenoxy) phenyl]sulfonyl]amino]-N-hydroxy-2-methylpropanamide; CP 471474. Grades: Highly Purified. CAS No. 210755-45-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CP-472555
CP-472555 is an effective Glucocorticoid receptor agonist and probably has steroid-like anti-inflammatory properties with anti-GR and anti-obesity activity in animal models. Uses: Glucocorticoid receptor antagonists. Synonyms: CP-472555; CP 472555; CP472555; UNII-6T0KV7024R. 2-Phenanthrenecarboxamide, 4b,5,6,7,8,8a,9,10-octahydro-7-hydroxy-4b-(phenylmethyl)-7-(1-propyn-1-yl)-N-(3-pyridinylmethyl)-, (4bS,7R,8aR)-. Grades: ≥95%. CAS No. 305821-96-9. Molecular formula: C31H32N2O2. Mole weight: 464.24.
CP-47947
CP-47947. Group: Biochemicals. Alternative Names: rel-5- (1, 1-dimethylheptyl) -2- [ (1R, 3S) -3-hydroxycyclohexyl] phenol; (+/-)-CP 47497; CP 47947. Grades: Highly Purified. CAS No. 70434-82-1. Pack Sizes: 1mg, 2mg. Molecular Formula: C21H34O2. US Biological Life Sciences.
Worldwide
CP-47947 Benzyl Ether
CP-47947 derivative. A cannabinoid receptor ligand. Group: Biochemicals. Alternative Names: cis-3-[4-(1,1-Dimethylheptyl)-2-(phenylmethoxy)phenyl]-cyclohexanol. Grades: Highly Purified. CAS No. 70434-49-0. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
CP-481715
CP-481715 is a potent and selective CCR1 antagonist with >100-fold selective for CCR1 as compared with a panel of G-protein-coupled receptors including related chemokine receptors. CP-481,715 inhibits cell infiltration and inflammatory responses in human CCR1 transgenic mice. Synonyms: N-[(2S,3S,5R)-5-carbamoyl-1-(3-fluorophenyl)-3,8-dihydroxy-8-methylnonan-2-yl]quinoxaline-2-carboxamide; CP 481,715; CP 481715; CP-481,715; CP-481715; CP481,715; CP481715; quinoxaline-2-carboxylic acid (4-carbamoyl-1-(3-fluorobenzyl)-2,7-dihydroxy-7-methyloctyl)amide. Grades: >98%. CAS No. 212790-31-3. Molecular formula: C26H31FN4O4. Mole weight: 482.55.
Cp4G
Cp4G, an invaluable compound extensively used in the biomedical sector to study G protein-coupled receptors (GPCRs) is bestowed with unmatched affinity towards GPR120, a receptor that holds immense therapeutic promise to combat obesity and type 2 diabetes. Having demonstrated pronounced efficacy, Cp4G presents an exciting avenue for drug development in the fight against these rampant maladies. Synonyms: P1- (5'- Cytidyl)- P4- (5'- guanosyl)- tetraphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 79695-24-2. Molecular formula: C19H28N8O21P4 (free acid). Mole weight: 828.4 (free acid).
CP-5068
CP-5068 is a synthetic bio-active chemical. Uses: A synthetic bio-active chemical. Synonyms: CP-5068; CP 5068; CP5068; UNII-0UZY88DX6N. (4S,5R,6S)-3-[6-(2-amino-2-oxoethyl)-7-methylsulfanylimidazo[5,1-b][1,3]thiazol-6-ium-2-yl]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate. Grades: ≥98%. CAS No. 352305-79-4. Molecular formula: C18H20N4O5S2. Mole weight: 436.08.
CP-532623
CP-532623, structurally related to Torcetrapib, is a potent inhibitor of cholesteryl ester transfer protein (CETP). Synonyms: CP-532623; CP 532623; CP532623; UNII-5KK52HG8D; 10-[3-(4-hydroxypiperidin-1-yl)propyl]phenothiazine-2-carbonitrile. Grades: >98%. CAS No. 261947-38-0. Molecular formula: C27H27F9N2O3. Mole weight: 598.5.
CP-533536
CP-533536, also called as Evatanepag, a 3-pyridyl sulfonamide compound, demonstrated excellent in vitro potency against prostaglandin E2 (PGE2) (induces local bone formation with EC50= 0.3 nM) and selectivity against a broad panel of other targets. Synonyms: 2- [3- [ [ (4-tert-butylphenyl) methyl-pyridin-3-ylsulfonylamino] methyl] phenoxy] acetic acid(3-((4-tert-butylbenzyl)-(pyridine-3-sulfonylamino)methyl)phenoxy)acetic acidCP-533536; CP 533536; CP533536; Evatanepag. Grades: 95%. CAS No. 223488-57-1. Molecular formula: C25H28N2O5S. Mole weight: 468.56.
CP-53631
CP-53631 is a selective serotonin reuptake inhibitor (SSRI); antidepressant. Group: Biochemicals. Alternative Names: (1R,4S)-rel-4-(4-Bromophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine Hydrochloride; trans-4-(4-Bromophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine Hydrochloride; trans-(±)-4-(4-Bromophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine Hydrochloride. Grades: Highly Purified. CAS No. 79836-56-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CP 544326
CP 544326, also known as taprenepag, is a potent and selective EP(2) receptor agonist. Its EC50 value is 2.8 nM. It is the active acid metabolite of the prodrug PF-04217329. It was successfully evaluated for its ocular hypotensive activity in a clinical study involving patients with primary open angle glaucoma. Uses: Cp 544326 was successfully evaluated for its ocular hypotensive activity in a clinical study involving patients with primary open angle glaucoma. Synonyms: CP-544326; CP544326, CP544326, Taprenepag, PF-0421732 metabolite; 2-(3-((N-(4-(1H-pyrazol-1-yl)benzyl)pyridine-3-sulfonamido)methyl)phenoxy)acetic acid; CP-544326; CP544326; CP544326; Taprenepag; PF-0421732 metabolite. Grades: 98%. CAS No. 752187-80-7. Molecular formula: C24H22N4O5S. Mole weight: 478.52.
CP-544439
CP-544439 is a selective matrix metalloproteinase-13 inhibitor. Uses: Matrix metalloproteinase inhibitors. Synonyms: 4-[[4-(4-fluorophenoxy)phenyl]sulfonylamino]-N-hydroxyoxane-4-carboxamide; CP-544439; CP 544439; CP544439 ; UNII-516DO4KL5R. Grades: >98%. CAS No. 230954-09-3. Molecular formula: C18H19FN2O6S. Mole weight: 410.42.
CP-547632
CP-547632 is as a potent inhibitor of the VEGFR-2 and basic fibroblast growth factor (FGF) kinases (IC50 11 and 9 nM, respectively). It is selective relative to epidermal growth factor receptor, platelet-derived growth factor , and other related TKs. It also inhibits VEGF-stimulated autophosphorylation of VEGFR-2 in a whole cell assay with an IC50 value of 6 nM. After oral administration of CP-547,632 to mice bearing NIH3T3/H-ras tumors, VEGFR-2 phosphorylation in tumors was inhibited in a dose-dependent fashion (EC50 590 ng/ml). CP-547,632 is a well-tolerated, orally-bioavailable inhibitor presently under clinical investigation for the treatment of human malignancies. Synonyms: CP547632; CP 547632; CP-547632; PAN90806; PAN 90806; PAN-90806; CP632; OSI632; CP 632; OSI 632; CP-632; OSI-632. CAS No. 252003-65-9. Molecular formula: C20H24BrF2N5O3S. Mole weight: 532.405.
CP-5484
CP-5484 is a synthetic bio-active chemical with potent anti-MRSA activity and low acute toxicity. Uses: A synthetic bio-active chemical with potent anti-mrsa activity and low acute toxicity. Synonyms: CP-5484; CP 5484; CP5484; UNII-A53TMV6VUN. (4S,5R,6S)-3-[6-[(2R)-3-amino-2-hydroxypropyl]-7-methylsulfanylimidazo[5,1-b][1,3]thiazol-6-ium-2-yl]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid;chloride. Grades: ≥98%. CAS No. 352308-27-1. Molecular formula: C19H25ClN4O5S2. Mole weight: 489.00.
CP-5609
CP-5609 is a novel carbapenem with enhanced antimicrobial activities. Uses: Antimicrobial activities. Synonyms: CP-5609; CP 5609; CP5609; ME-1036; ME 1036;ME1036; UNII-33501R83O2. Pyridinium, 1-(2-amino-2-oxoethyl)-3-((2-((4S,5R,6S)-2-carboxy-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo(3.2.0)hept-2-en-3-yl)imidazo(5,1-b)thiazol-7-yl)carbonyl)-, inner salt. Grades: ≥95%. CAS No. 432038-96-5. Molecular formula: C23H21N5O6S. Mole weight: 495.51.
CP 59430
CP 59430 is an azide analog of prazosin. It is a selective alpha 1-adrenergic receptor antagonist. Synonyms: CP 59430; CP59430; CP-59430. 2-(4-(4-Azidobenzoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline. Grades: 98%. CAS No. 86329-06-8. Molecular formula: C21H22N8O3. Mole weight: 434.45.
CP-601927
CP-601927 is a CNS-penetrant, high affinity, and selective nicotinic acetylcholine receptor (nAChR) agonist. Uses: Nachr agonist. Synonyms: CP-601927; CP 601927; CP601927; CP-601,927; UNII-VI5LR1EU47; 1,5-Methano-1H-3-benzazepine, 2,3,4,5-tetrahydro-7-(trifluoromethyl)-, (1R,5S)-. Grades: ≥98%. CAS No. 357425-02-6. Molecular formula: C12H12F3N. Mole weight: 227.09.
CP-601932
CP-601932 is a CNS-penetrant, high affinity, and selective α(4) β(2) nicotinic acetylcholine receptors partial agonist. Uses: Nachr agonist. Synonyms: CP-601932; CP 601932; CP601932; CP-601,927; UNII-VI5LR1EU47; 1,5-Methano-1H-3-benzazepine, 2,3,4,5-tetrahydro-7-(trifluoromethyl)-, (1R,5S)-. Grades: ≥98%. CAS No. 357425-68-4. Molecular formula: C12H12F3N. Mole weight: 227.23.
CP-608039
CP-608039 is a selective adenosine A3 receptor agonist with 1,260-fold selectivity for the human A3 versus human A1 receptor. Uses: A selective adenosine a3 receptor agonist. Synonyms: CP-608039; CP608039; CP 608039; UNII-A1LB8I4247. (2S,3S,4R,5R)-3-amino-5-[6-[[5-chloro-2-[(3-methyl-1,2-oxazol-5-yl)methoxy]phenyl]methylamino]purin-9-yl]-4-hydroxy-N-methyloxolane-2-carboxamide. Grades: ≥98%. CAS No. 331727-55-0. Molecular formula: C23H25ClN8O5. Mole weight: 528.16.
CP-60949-4
CP-60949-4, a quinazolin derivative, could be probably useful in sorts of biological studies. Synonyms: CP 60949-4; CP60949-4; CP-609494. AC1L1YFM; CP 60949-4; 6-bromo-7-chloro-3-[3-(3-hydroxypiperidin-2-yl)-2-oxopropyl]quinazolin-4-one hydrobromide; 4(3H)-Quinazolinone, 6-bromo-7-chloro-3-(3-(3-hydroxy-2-piperidinyl)-2-oxopropyl)-, monohydrobromide. Grades: 98%. CAS No. 17518-97-7. Molecular formula: C16H18Br2ClN3O3. Mole weight: 495.60.
CP-609754
CP-609754, also known as CP-609,754,LNK 754 and OSI 754, is a potent arnesyltransferase inhibitor with potential anticancer activity. Synonyms: CP-609754; CP609754; CP 609754; CP-609,754; CP609,754; CP 609,754; LNK 754; LNK754; LNK-754; OSI 754; OSI754; OSI-754. CAS No. 1190094-64-4. Molecular formula: C29H22ClN3O2. Mole weight: 479.964.
CP 615003 mesylate
CP 615003 mesylate is a potent and selective GABAA receptor partial agonist potentially useful in treating generalized anxiety disorder. Uses: Potential treatment of anxiety. Synonyms: CP 615003 mesylate; CP615003 mesylate; CP-615003 mesylate; N-(3-fluoro-4-(2-(propylamino)ethoxy)phenyl)-4,5,6,7-tetrahydro-4-oxo-1H-indole-3-carboxamide mesylate. Grades: 99%. CAS No. 1259477-42-3. Molecular formula: C20H24FN3O3.CH4O3S. Mole weight: 469.53.
CP 6232
CP 6232 is a new anti-pseudomonal cephalosporin as a cell wall inhibitor. It was developed by Meiji Seika Pharma. Research for the treatment of bacterial infections was discontinued. Uses: Bacterial infections. Synonyms: CP 6232; CP6232; CP-6232. 7-((2-Aminothiazol-4-yl)-2-(1-carboxy-1-methyl)ethoxyiminoacetamido)-3-(N-(1,5-dihydroxy-4-pyridon-2-yl)methyl-N-methyl)aminomethyl-3-cephem-4-carboxylic acid. Grades: 98%. CAS No. 141562-38-1. Molecular formula: C24H27N7O10S2. Mole weight: 637.65.
CP-640186
CP-640186 is a potent inhibitor of mammalian ACCs and can reduce body weight and improve insulin sensitivity in test animals. It has recently been shown to be a potent inhibitor of isoforms of mammalian ACCs. Most importantly, CP-640186 can reduce body fat mass and body weight, and improve insulin sensitivity, validating ACCs as targets for antiobesity and antidiabetes drugs. Synonyms: CP-640186; CP 640186; CP640186. Grades: >98%. CAS No. 591778-68-6. Molecular formula: C30H35N3O3. Mole weight: 485.62.
CP-640186
CP-640186 is an orally active and cell-permeable Acetyl-CoA carboxylase ( ACC ) inhibitor with IC 50 s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. Acetyl-CoA carboxylase (ACC) is a key enzyme of fatty acid metabolism that enables the synthesis of malonyl-CoA. CP-640186 can also stimulate muscle fatty acid oxidation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 591778-68-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15259.
CP640186 HCl
CP-640186 is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively; with improved metabolic stability vs CP-610431. Synonyms: CP640186; CP 640186. Grades: 0.98. CAS No. 591778-70-0. Molecular formula: C30H36ClN3O3. Mole weight: 522.09.
CP-640186 hydrochloride
CP-640186 hydrochloride is an orally active and cell-permeable Acetyl-CoA carboxylase ( ACC ) inhibitor with IC 50 s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. Acetyl-CoA carboxylase (ACC) is a key enzyme of fatty acid metabolism that enables the synthesis of malonyl-CoA. CP-640186 hydrochloride can also stimulate muscle fatty acid oxidation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 591778-70-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15259A.
CP654577
CP654577 is a selective p185(erbB2) kinase inhibitor. It could reduce the levels of the activated form of mitogen-activated protein kinase of SKBr3 human breast cancer cells. Synonyms: CP-654577; CP 654577; 3-Azabicyclo(3.1.0)hexane-6-methanol, 3-((4-(4-((3-methoxy-4-phenoxyphenyl)amino)-6-quinazolinyl)phenyl)methyl)-, (1alpha,5alpha,6alpha)-. Grades: 98%. CAS No. 639087-64-2. Molecular formula: C34H32N4O3. Mole weight: 544.65.
CP-664511
CP-664511 is a potent compound that is a alpha4beta1/vascular cell adhesion molecule-1 (VCAM-1) inhibitor which has therapeutic potential in treating allergic airway disease. Uses: Alpha4bet1/vcam-1 inhibitor. Synonyms: CP-664511; CP 664511; CP664511; UNII-W1AEF8025F. 3- ( (1S) -1- ( ( (3-methoxy-4- ( ( ( (2-methylphenyl) amino) carbonyl) amino) phenyl) acetyl) amino) -3-methylbutyl) -5-Isoxazolepropanoic acid. Grades: ≥98%. CAS No. 379692-00-9. Molecular formula: C28H34N4O6. Mole weight: 522.59.
CP-66713 Mesylate Salt
CP-66713 is an adenosine A2 receptor antagonist, a potential new diagnostic tool for neurological disorders. Group: Biochemicals. Alternative Names: 8-Chloro-1-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-amine Monomethanesulfonate. Grades: Highly Purified. CAS No. 91896-58-1. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CP66,948
CP66,948 is a histamine H2-receptor antagonist. It has gastric antisecretory activity and mucosal protective properties. Uses: Cp66,948 has gastric antisecretory activity and mucosal protective properties. Synonyms: CP66,948; CP 66,948; CP-66,948; CP 66948; 2-(N-Pentyl-N'-guanidino)-4-(2-methylimidazol-4-yl)thiazole;CP-66,948CP-66,948;1-[4-(2-methyl-1H-imidazol-5-yl)-1,3-thiazol-2-yl]-2-pentylguanidine. Grades: >98 %. CAS No. 101189-47-3. Molecular formula: C13H20N6S. Mole weight: 292.40.
CP-67015
CP-67015 has inhibitory effect on topoisomerase function. It is a direct-acting mutagen in mammalian cells with both gene and chromosomal level effects. Uses: Cp-67015 has inhibitory effect on topoisomerase function. Synonyms: 1-Ethyl-6,8-difluoro-1,4-dihydro-4-oxo-7-(4-pyridinyl)-3-quinolinecarboxylic acid;3-Quinolinecarboxylicacid, 1-ethyl-6,8-difluoro-1,4-dihydro-4-oxo-7-(4-pyridinyl)-;CP 67015; CP 67015; CP 67015; CCRIS 2955; CP-67,015. Grades: >98 %. CAS No. 100325-51-7. Molecular formula: C17H12F2N2O3. Mole weight: 330.29.
CP-671305
CP-671305 is a potent and selective inhibitor of PDE4. Uses: Pde4 inhibitor. Synonyms: CP-671305; CP 671305; CP671305; UNII-9LH034R9R9. (R)-2-(4-((((2-((Benzo(1,3)dioxol-5-yl)oxy)pyridin-3-yl)carbonyl)amino)methyl)-3-fluorophenoxy)propionic acid. Grades: ≥98%. CAS No. 445295-04-5. Molecular formula: C23H19FN2O7. Mole weight: 54.4.
CP-671906-01
CP-671906-01 is a neuropeptide Y1 receptor antagonists, increasing blood pressure and food intake in rat models. Uses: Npy y1r antagonist. Synonyms: CP-671906; CP 671906; CP671906; UNII-GLZ1WA47Q8; CP-671906-01.N'-[3-(2,6-dichloro-4-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl]-N-(oxan-4-yl)ethane-1,2-diamine. Grades: ≥98%. CAS No. 332178-44-6. Molecular formula: C22H27Cl2N5O2. Mole weight: 464.39.
CP-673451
CP-673451 is a selective inhibitor of PDGFRα/β with IC50 of 10 nM/1 nM, exhibits >450-fold selectivity over other angiogenic receptors, has antiangiogenic and antitumor activity. Synonyms: CP-673451; CP673451; CP 673451; CP-673,451; CP 673451; CP 673,451. Grades: >98%. CAS No. 343787-29-1. Molecular formula: C24H27N5O2. Mole weight: 417.5.
CP-67804 enhances topoisomerase II-mediated DNA cleavage. It represent a novel class of topoisomerase II-targeted drugs which have potential as antineoplastic agents. Uses: Cp-67804 has the potential to be used as antineoplastic agents. Synonyms: CP 67804; CP67804; CP-67804; CCRIS 8213; CP-67,804. 3-Quinolinecarboxylicacid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-(4-hydroxyphenyl)-4-oxo-;CP67804;1-Ethyl-6,8-difluoro-7-(4-hydroxyphenyl)-4-quinolone-3-carboxylic acid. Grades: >98 %. CAS No. 103978-08-1. Molecular formula: C18H13F2NO4. Mole weight: 345.30.
CP-690550A
This active molecular is a novel Janus Kinase 3 (JAK3) inhibitor. CP-690550A is an immunosuppressant for the treatment of rheumatoid arthritis, psoriasis, transplant rejection and other immune-mediated disorders. Uses: Immune-mediated disorders. Synonyms: CP-690550A; CP-690,550A; CP 690550A; CP690550A; Tofacitinib metabolite M2; UNII-Q7ZOK859UK; Tofacitinib metabolite M2; Q7ZOK859UK; CHEMBL1630791; 2-hydroxy-1-[(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]ethanone. Grades: 98%. CAS No. 1243290-37-0. Molecular formula: C15H21N5O2. Mole weight: 303.37.