A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
CGMP is required to activate this enzyme. The enzyme occurs as a dimer in higher eukaryotes. The C-terminal region of each polypeptide chain contains the catalytic domain that includes the ATP and protein substrate binding sites. This domain catalyses the phosphorylation by ATP to specific serine or threonine residues in protein substrates. The enzyme also has two allosteric cGMP-binding sites (sites A and B). Binding of cGMP causes a conformational change that is associated with activation of the kinase. Group: Enzymes. Synonyms: 3':5'-cyclic GMP-dependent protein kinase; cGMP-dependent protein kinase Iβ; guanosine 3':5'-cyclic monophosphate-dependent protein kinase; PKG; PKG 1α; PKG 1β; PKG II; STK23. Enzyme Commission Number: EC 2.7.11.12. CAS No. 141588-27-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3131; cGMP-dependent protein kinase; EC 2.7.11.12; 141588-27-4; 3':5'-cyclic GMP-dependent protein kinase; cGMP-dependent protein kinase Iβ; guanosine 3':5'-cyclic monophosphate-dependent protein kinase; PKG; PKG 1α; PKG 1β; PKG II; STK23. Cat No: EXWM-3131.
CGP11952
Cgp-11952 is an experimental benzodiazepine derivative. It has affects on cognitive functioning. Uses: Cgp-11952 has affects on cognitive functioning. Synonyms: 1H-1,2,4-Triazole-3-carboxamide, 1-[4-chloro-2-(2-chlorobenzoyl)phenyl]-5-[(dimethylamino)methyl]-N-ethyl-; Cgp 11952; Cgp-11952; 1-[4-Chloro-2-(2-chlorobenzoyl)phenyl]-5-[(dimethylamino)methyl]-N-ethyl-1H-1,2,4-triazole-3-carboxamide. Grade: 98%. CAS No. 64078-09-7. Molecular formula: C21H21Cl2N5O2. Mole weight: 446.33.
CGP 12177
CGP 12177 is a partial β3-adrenoceptor agonist with Ki value of 88 nM. It is also an of β1- and β2-adrenoceptors antagonist with Ki values of 0.9 nM and 4 nM for β1-, β2adrenoceptors. CGP12177 can slightly activate L-type Ca2+ current in human ventricular myocytes. Uses: Adrenergic beta-antagonists. Synonyms: CGP 12177; CGP12177; CGP-12177; Tbhpbo; CGP 12177 Hydrochloride; CGP 12177 HCl. 4-[3-[(1,1-Dimethylethyl)amino]2-hydroxypropoxy]-1,3-dihydro-2H-benzimidazol-2-one; 64208-32-8(hydrochloride). Grade: 98%. CAS No. 81047-99-6. Molecular formula: C14H21N3O3. Mole weight: 279.34.
CGP 12177 hydrochloride
CGP 12177 ((±)-CGP 12177) hydrochloride is a β Adrenergic Receptor Ligand. CGP 12177 hydrochloride is a high affinity antagonist of β1- and β2-AR. CGP 12177 hydrochloride is also shown to interact, with a lower affinity, with the β3-AR and to exhibit a partial agonist activity on rodent and human β3-AR. CGP 12177 hydrochloride exhibits partial agonist properties for α1-AR in rat pulmonary artery [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-CGP 12177 hydrochloride. CAS No. 64208-32-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-101393A.
CGP 12177 hydrochloride
CGP 12177 hydrochloride is a partial agonist of β3-adrenoceptors, and also an antagonist of β1- and β2-adrenoceptors (Ki = 0.9, 4 and 88 nM for β1, β2 and β3 receptors respectively). Synonyms: CGP 12177 hydrochloride; CGP12177 hydrochloride; CGP-12177 hydrochloride; 4-[3-[(1,1-Dimethylethyl)amino]2-hydroxypropoxy]-1,3-dihydro-2H-benzimidazol-2-one hydrochloride. CAS No. 64208-32-8. Molecular formula: C14H21N3O3.HCl. Mole weight: 315.8.
CGP 12177 hydrochloride
CGP 12177 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 64208-32-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CGP-12388
CGP-12388 is a beta-adrenoceptor antagonist-derived radioligands. It is used for cardiac PET imaging due to its high hydrophilicity and affinity to beta-adrenoceptor. Uses: Cgp-12388 is used for cardiac pet imaging due to its high hydrophilicity and affinity to beta-adrenoceptor. Synonyms: 4-(3-(Isopropylamino)-2-Hydroxypropoxy)-2H-Benzimidazol-2-One; Cgp 12388; Cgp-12388; Cgp12388; 2H-Benzimidazol-2-one, 4-(3-(isopropylamino)-2-hydroxypropoxy)-; 4-[2-hydroxy-3-(propan-2-ylamino)propoxy]benzimidazol-2-one. Grade: 95%. CAS No. 108929-47-1. Molecular formula: C13H19N3O3. Mole weight: 263.29.
Cgp 13143
Cgp 13143 is a bio-active chemical,but no detailed information has been published yet. Synonyms: Cgp 13143; Cgp13143; Cgp-13143. ((4-methyl-2-oxo-2H-1-benzopyran-6-yl)amino)oxo-Acetic acid. Grade: 98%. CAS No. 75919-69-6. Molecular formula: C12H9NO5. Mole weight: 247.21.
Cgp 13231
Cgp 13231 is the N-oxide metabolite of amocarzine. Synonyms: Cgp 13231; Cgp13231; Cgp-13231. 1-Piperazinecarbothioamide, 4-methyl-N-(4-((4-nitrophenyl)amino)phenyl)-4-oxide. Grade: 98%. CAS No. 113962-61-1. Molecular formula: C18H21N5O3S. Mole weight: 387.46.
CGP 13501
CGP 13501 is a positive allosteric modulator of GABAB receptors, potentiating the effects of GABA at this receptor type. Uses: Gaba-b receptor agonists. Synonyms: CGP13501; CGP 13501; CGP-13501; 3,5-bis(1,1-Dimethylethyl)-4-hydroxy-α,α-dimethylbenzenepropanal. Grade: ≥98% by HPLC. CAS No. 56189-68-5. Molecular formula: C19H30O2. Mole weight: 290.44.
CGP 13501
CGP 13501. Group: Biochemicals. Grades: Purified. CAS No. 56189-68-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Cgp 15425 is a bio-active chemical,but no detailed information has been published yet. Synonyms: Cgp 15425; Cgp15425; Cgp-15425. (S)-N1-((2S,5S,8R,11S,14S,17S)-8-((1H-indol-3-yl)methyl)-11-(4-aminobutyl)-5,17-dibenzyl-14-((R)-1-hydroxyethyl)-19-imino-3,6,9,12,15,18,22-heptaoxo-1-phenyl-4,7,10,13,16-pentaazadocosan-2-yl)-2-aminosuccinamide. Grade: 98%. CAS No. 76080-70-1. Molecular formula: C56H69N11O10. Mole weight: 1056.21.
CGP-15720 hydrochloride
CGP-15720 is a antitumor agent. Uses: Antitumor. Synonyms: CGP-15720 hydrochloride; CGP-15720 HCl; CGP-15720A; CGP15720A; UNII-73G6V7978M. 4-(3-(2-(2-(pyridin-4-yl)-4,5-dihydro-1H-imidazol-1-yl)ethyl)ureido)benzoic acid hydrochloride. Grade: 98%. CAS No. 76692-12-1. Molecular formula: C18H20ClN5O3. Mole weight: 389.84.
Cgp-17520
Cgp-17520 is a new bio-active cephalosporin anti-biotic chemical comound synthesized by Ciba Geigy Ltd. Synonyms: Cgp 17520; Cgp-17520; Cgp17520. 7-(2-(4-(((2-Amino-2-carboxyethoxy)carbonyl)amino)phenyl)-2-hydroxyacetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt. Grade: >98 %. CAS No. 101706-66-5. Molecular formula: C22H24N8NaO9S2. Mole weight: 631.59.
CGP-1758 monomethanesulfonate
CGP-1758 monomethanesulfonate is a new bio-active cephalosporin anti-biotic chemical comound synthesized by Ciba Geigy Ltd. Synonyms: CGP 1758B; CGP-1758B; CGP1758B. 2-Hydroxy-5-[2-[[2-hydroxy-3-[4-(2-methoxyethoxy)phenoxy]propyl]amino]ethoxy]benzamide monomethanesulfonate; CGP1758 monomethanesulfonate. Grade: >98%. CAS No. 108289-44-7. Molecular formula: C22H32N2O10S. Mole weight: 516.56.
Cgp 20309
Cgp 20309 has a thiocarbonylamides structure and it is a potent antifilarial agent under laboratory research stage. Uses: Antifilarial agent. Synonyms: Cgp 20309; Cgp20309; Cgp-20309. N-(2-(1,1-dimethylethyl)-5-methoxy-6-benzothiazolyl)-4-methyl-1-Piperazinecarbothioamide. Grade: 98%. CAS No. 122378-48-7. Molecular formula: C18H26N4OS2. Mole weight: 378.56.
CGP 20376
CGP 20376 is a benzothiazole compound and it has antifilarial properties. Uses: Antifilarial agent. Synonyms: CGP 20376; CGP20376; CGP-20376. 3-((((2-(1,1-dimethylethyl)-5-methoxy-6-benzothiazolyl)amino)thioxomethyl)thio)-Propanoic acid; N-(2-tert-Butyl-5-methoxybenzothiazol-6-yl)dithiocarbonic acid 5-(1-carboxyethyl)ether. Grade: 98%. CAS No. 81059-04-3. Molecular formula: C16H20N2O3S3. Mole weight: 384.54.
CGP 20712 dihydrochloride is a potent and selective β1-adrenoceptor antagonist (IC50 = 0.7 nM) with 10,000-fold selectivity over β2-adrenoceptors. Synonyms: CGP 20712A Dihydrochoride; CGP 20712ADihydrochoride; CGP 20712A; CGP20712A; CGP-20712A. SR-01000076208; 1-[2-((3-Carbamoyl-4-hydroxy)phenoxy)ethylamino]-3-[4-(1-methyl-4-trifluoromethyl-2-imidazolyl)phenoxy]-2-propanol dihydrochloride. Grade: ≥96% by HPLC. CAS No. 1216905-73-5. Molecular formula: C23H25F3N4O5.2HCl. Mole weight: 567.39.
CGP 20712 dihydrochloride
CGP 20712 dihydrochloride is a highly selective β1-adrenoceptor antagonist with an IC 50 of 0.7 nM. CGP 20712 dihydrochloride exhibits ~10,000-fold selectivity over β2-adrenoceptors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1216905-73-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-101355A.
CGP 20712 dihydrochloride
CGP 20712 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1216905-73-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Cgp 21833
Cgp 21833 has a thiocarbonylamides structure and it is a potent antifilarial agent under laboratory research stage. Uses: Antifilarial agent. Synonyms: Cgp 21833; Cgp-21833; Cgp21833. 1-(2-(1,1-dimethylethyl)-5-methyl-6-benzothiazolyl)-2-methylhydrazide 1-Piperazinecarbothioic acid. Grade: 98%. CAS No. 122378-49-8. Molecular formula: C18H27N5S2. Mole weight: 377.57.
CGP 23996
CGP 23996 is a non-reducible somatostatin analog. It can be used for autoradiography. Uses: Autoradiography. Synonyms: CGP 23996; CGP23996; CGP-23996. BDBM82467; 2-Deamino-L-Abu(1)-L-Lys-L-Asp(NH2)-L-Phe-L-Phe-L-Trp-L-Lys-L-Thr-L-Tyr-L-Thr-L-Ser-L-Abu(1)-OH; (14R,20S,23R,26R,29R,32R)-2,17-bis(4-aminobutyl)-5-(2-amino-2-oxoethyl)-8,11-dibenzyl-20,26-bis[(1S)-1-hydroxyethyl]-29-(hydroxymethyl)-23-[(4-hydroxyphenyl)methyl]-14-(1H-indol-3-ylmethyl)-3,6,9,12,15,18,21,24,27,30,38-undecaoxo-1,4,7,10,13,16,19,22,25,28,31-undecazacyclooctatriacontane-32-carboxylic acid. Grade: 98%. CAS No. 86170-12-9. Molecular formula: C73H99N15O18. Mole weight: 1474.66.
CGP 25454A
CGP 25454A is a selective antagonist of presynaptic dopamine autoreceptor. Synonyms: N-(diethylaminoethyl)-4-chloro-5-cyano-2-methoxybenzamide hydrochloride; Benzamide, 4-chloro-5-cyano-N-[2-(diethylamino)ethyl]-2-methoxy-, hydrochloride (1:1); CGP-25454A; CGP25454A. Grade: ≥95%. CAS No. 104391-26-6. Molecular formula: C15H21Cl2N3O2. Mole weight: 346.25.
Cgp 29030A
This molecular is a piperazine derivative and its Pharmacological activity probablely is inhibition on nociceptive dorsal horn neurons that processed input from high-threshold mechanosensitive receptors in the skin and deep somatic tissues.It may be used to treat painful disorders which are complicated by increased motor. activity. Uses: Treat painful disorders. Synonyms: Cgp 29030A; Cgp29030A; Cgp-29030A. 1-p-chlorophenethyl-4-(3,5-dimethoxybenzoyl)piperazine hydrochloride. Grade: 98%. CAS No. 113240-27-0. Molecular formula: C21H26Cl2N2O3. Mole weight: 425.35.
Cgp 29287
Cgp 29287 is a renin inhibitor with a prolonged duration of action. Synonyms: CGP-29287; Z-Arg-Arg-Pro-Phe-His-Sta-Ile-His-Nepsilon-Boc-Lys methyl ester. Grade: 95%. CAS No. 93287-54-8. Molecular formula: C72H110N20O15. Mole weight: 1495.77.
Cgp 31358
CGP 31358 is a compound that can bind to a site on the N-methyl-D-aspartate (NMDA) receptor which is coupled to both the transmitter recognition site and the channel domain.It can be a tool for researching the molecular pharmacology of this receptor-channel complex. Uses: A tool for researching the molecular pharmacology of receptor-channel complex. Synonyms: Cgp 31358; Cgp-31358; Cgp31358; 1-(4-(1-(4-chlorophenyl)-1-methylethyl)-2-methoxyphenyl)-1H-1,2,4-Triazole-3-carboxamide. Grade: 98%. CAS No. 125652-47-3. Molecular formula: C19H19ClN4O2. Mole weight: 370.83.
Cgp-33304
Cgp-33304 is a dual phospholipase A2 inhibiting agent and leukotriene receptor antagonists. It may prevent hypoxia secondary to leukotriene induced bronchoconstriction in shock states. It has potential to be an useful therapeutic agent in acute ischemic disorders including traumatic shock. Uses: Cgp-33304 has potential to be an useful therapeutic agent in acute ischemic disorders including traumatic shock. Synonyms: Cgp 33304; Cgp33304; Cgp-33304; 1H-Tetrazole-5-carboxamide, N-(5-(3-(4-acetyl-3-hydroxy-2-propylphenox y)propoxy)-4-bromo-2-methylphenyl)-, monosodium salt; CGP33304; N-(3-(3-(4-Acetyl-3-hydroxy-2-n-propylphenoxy)propoxy)-4-bromo-6-methylphenyl)-1H-tetrazole-5-carboxamide sodium; Sodium 5-((5-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy)-4-bromo-2-methylphenyl)carbamoyl)tetrazol-1-ide. Grade: >98%. CAS No. 111130-14-4. Molecular formula: C23H25BrN5NaO5. Mole weight: 554.38.
CGP 3466B maleate
CGP 3466B maleate, a potent anti-apoptotic drug, is an orally active glyceraldehyde-3-phosphate dehydrogenase (GAPDH) inhibitor. CGP 3466B maleate was tested in clinical trials for its ability to help treat Parkinson's disease (PD) and amyotrophic lateral sclerosis (ALS) but the clinical trials have been terminated due to lack of benefit. Synonyms: N-(benzo[b][1]benzoxepin-5-ylmethyl)-N-methylprop-2-yn-1-amine; but-2-enedioic acid; Omigapil maleate; CGP 3466B; CGP-3466B; CGP3466B; TCH-346; TCH 346; TCH346; Omigapil maleate. Grade: >99 %. CAS No. 200189-97-5. Molecular formula: C23H21NO5. Mole weight: 391.42.
CGP 3466B maleate
CGP 3466B maleate. Group: Biochemicals. Grades: Purified. CAS No. 200189-97-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CGP35348
CGP 35348 is a selective, brain penetrant, centrally active GABAB receptor antagonist with an EC 50 of 34 μM. CGP 35348 shows affinity for the GABAB receptor only [1]. CGP 35348 has a potential to improve neuromuscular coordination and spatial learning in albino mouse following neonatal brain damage [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 123690-79-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103530.
CGP 35348
CGP 35348 is a selective and brain penetrant GABAB receptor antagonist (IC50 = 34 μM as measured in rat cortical membranes) with higher affinity for postsynaptic than presynaptic receptors. Synonyms: CGP35348; CGP-35348; (3-Aminopropyl)(diethoxymethyl)phosphinic acid. Grade: 95% by NMR. CAS No. 123690-79-9. Molecular formula: C8H20NO4P. Mole weight: 225.22.
A selective antagonist of post-synaptic GABAB receptors (IC50 = 34uM) that can permeate the blood brain barrier. Exhibits about 10-fold lower affinity for pre-synaptic receptors. Blocks K+-evoked glycine exocytosis in mouse spinal cord and hippocampal nerve endings. Shown to antagonize the potentiating effect of L-baclofen on noradrenaline-induced stimulation of adenylate cyclase in rat cortex slices. Group: Biochemicals. Grades: Highly Purified. CAS No. 123690-79-9. Pack Sizes: 10mg. US Biological Life Sciences.
Cgp-35949 is an LTD4 antagonist which has phospholipase inhibitory activity. It represents a new approach to the treatment of asthma. Uses: Cgp-35949 represents a new approach to the treatment of asthma. Synonyms: Cgp 35949; Cgp-35949; Cgp35949; 1H-Tetrazole-5-carboxamide, N-(5-(3-(4-acetyl-3-hydroxy-2-propylphenox y)propoxy)-4-chloro-2-methylphenyl)-, monosodium salt; CGP35949; N-(5-(3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propoxy)-4-chloro-2-methylphenyl)-1H-tetrazole-5-carboxamide monosodium salt; Sodium N-[5-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]-4-chloro-2-methylphenyl]-1,2,3-triaza-4-azanidacyclopenta-2,5-diene-5-carboxamide; Sodium 5-((5-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy)-4-chloro-2-methylphenyl)carbamoyl)tetrazol-1-ide. Grade: >98%. CAS No. 111130-13-3. Molecular formula: C23H25ClN5NaO5. Mole weight: 509.92.
CGP 36216
CGP 36216 hydrochloride is a selective GABAB antagonist that is active to presynaptic receptors but inactive to postsynaptic receptors. Synonyms: CGP 36216 hydrochloride; CGP36216 hydrochloride; CGP-36216 hydrochloride; (3-Aminopropyl)ethylphosphinic acid hydrochloride. Grade: ≥99% by HPLC. CAS No. 123691-29-2. Molecular formula: C5H14NO2P. Mole weight: 151.14.
CGP 36216 hydrochloride
CGP 36216 is a selective GABA antagonist with IC50 of 43 μM, which is active at the presynaptic but not postsynaptic. Synonyms: CGP 36216. Grade: ≥98%. CAS No. 1781834-71-6. Molecular formula: C5H14NO2P·HCl. Mole weight: 187.6.
CGP 36216 hydrochloride
CGP 36216 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 123691-29-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
CGP 36742 is a selective antagonist of GABAB receptor that can penetrate the blood-brain barrier after peripheral administration, with an IC50 of 32 μM. It can be used to study depression, seizures and metabolic diseases. Uses: Gaba antagonists. Synonyms: SGS-742; (3-Aminopropyl)(n-butyl)phosphinic acid; 3-aminopropyl-butylphosphinic acid; Phosphinic acid, P-(3-aminopropyl)-P-butyl-; Phosphinic acid, (3-aminopropyl)butyl-; P-(3-Aminopropyl)-P-butyl-phosphinic acid. Grade: 95%. CAS No. 123690-78-8. Molecular formula: C7H18NO2P. Mole weight: 179.20.
CGP37157
CGP37157 is a potent, selective inhibitor of Na+/Ca2+ exchanger, inhibiting the Na+-induced Ca2+-release from guinea-pig heart mitochondria, with an IC50 of 0.8 ?M. Uses: Scientific research. Group: Signaling pathways. CAS No. 75450-34-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15754.
CGP 37157
CGP 37157. Group: Biochemicals. Grades: Purified. CAS No. 75450-34-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CGP 37157
CGP 37157 is a a selective sodium-calcium exchanger inhibitor with IC50 value of 0.36 μM in isolated mitochondria. It does not affect channels, exchangers, or ATPases on the cardiac sarcolemma or ATPases on sarcoplasmic reticulum. CGP 37157 can be used to study the role of mitochondrial-derived calcium in cytoplasmic calcium homeostasis. Synonyms: Cgp 37157; Cgp-37157; Cgp37157. 7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one. Grade: 98%. CAS No. 75450-34-9. Molecular formula: C15H11Cl2NOS. Mole weight: 289.78.
A cell-permeable benzothiazepine derivative of clonazepam that acts as a specific and potent inhibitor of the mitochondrial Na+/Ca2+ exchanger (IC?? = 360 nM). Group: Fluorescence/luminescence spectroscopy.
CGP 37849
CGP 37849. Group: Biochemicals. Grades: Purified. CAS No. 127910-31-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
CGP 37849 is a potent, selective and competitive NMDA receptor antagonist (Ki = 35 nM). CGP 37849 exhibits an anticonvulsant effect following oral administration in vivo. Synonyms: CGP37849; CGP 37849; CGP-37849; (E)-(±)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid. Grade: ≥99% by HPLC. CAS No. 127910-31-0. Molecular formula: C6H12NO5P. Mole weight: 209.14.
CGP 37849
CGP 37849 is a potent, competitive and orally active N-methyl-D-aspartate (NMDA) receptor antagonist. CGP 37849 is an anticonvulsant in rodents and has antidepressant and anxiolytic-like effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 127910-31-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-107702.
A highly potent competitive antagonist selective fornMDA receptors (Ki = 35nM). Biologically viable admitted orally or systematically. Widely used in studies of epilepsy, schizophrenia, depression, stress and anxiety related mental disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 127910-31-0. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Cgp 38560
Cgp 38560 is a potent renin inhibitor and it can induce a dose-dependent decrease in angiotensin II and plasma renin activity and a long-lasting and dose-dependent rise in active renin. Although reduction of plasma renin activity to unmeasurable levels, the doses used did not reduce plasma angiotensin II maximally. Synonyms: Cgp 38560; Cgp38560; Cgp-38560. (R)-N-(2-(((1,1-dimethylethyl)sulfonyl)methyl)-1-oxo-3-phenylpropyl)-L-histidyl-3-cyclohexyl-L-alanyl-N-butyl-L-Valinamide monomethanesulfonate. Grade: 98%. CAS No. 122088-76-0. Molecular formula: C39H64N6O9S2. Mole weight: 825.09.
CGP 39551
Cgp 39551 is a selective and competitive N-methyl-D-aspartate (NMDA) receptor antagonist originated by Novartis. Ki is 310 nM for inhibition of [3H]-CPP binding in rat brain. CGP 39551 produces excitatory effects and causes psychotomimetic effects in humans. Treatment for Craniocerebral trauma, Epilepsy and Stroke was discontinued. Uses: Craniocerebral trauma, epilepsy and stroke. Synonyms: Cgp 39551; Cgp39551; Cgp-39551; (E)-(+/-)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester; CGP 39551; (E)-(-)-2-amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester. Grade: 98%. CAS No. 127910-32-1. Molecular formula: C8H16NO5P. Mole weight: 237.19.
CGP 39551
CGP 39551. Group: Biochemicals. Grades: Purified. CAS No. 127910-32-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Cgp 39653 is a competitive N-Methyl-D-aspartate (NMDA) receptor antagonist. CGP 39653 can selectively bins to the NMDA receptor as an antagonist with high affinity. It is currently the ligand of choice for labeling the NMDA receptor. Uses: The ligand of choice for labeling the nmda receptor. Synonyms: Cgp 39653; Cgp-39653; Cgp-39653; (R,Z)-2-amino-4-(phosphonomethyl)hept-3-enoic acid. Grade: 98%. CAS No. 132472-31-2. Molecular formula: C8H16NO5P. Mole weight: 237.19.
CGP 42112
CGP 42112. Group: Biochemicals. Grades: Purified. CAS No. 127060-75-7. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
CGP-42112
CGP-42112 (CGP-42112A) is a potent Angiotensin-II subtype 2 receptor(AT2 R) agonist[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGP42112A. CAS No. 127060-75-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-12405.
CGP-42112A, an angiotensin AT2 receptor agonist which could probably lead to the inhibition of ATPase and contraction of aortic rings in rabbit. Uses: Cgp-42112a is an angiotensin at2 receptor agonist which could probably lead to the inhibition of atpase and contraction of aortic rings in rabbit. Synonyms: Cgp 42112A; Cgp-42112A; Cgp42112A; Cgp 42112B; Cgp-42112B; Cgp42112B; CGP-42112; CGP 42112; CGP42112. Grade: ≥95%. CAS No. 127060-75-7. Molecular formula: C52H69N13O11. Mole weight: 1052.2.
CGP-42454A
CGP-42454A is a epimer of Benazepril ,an approved drug using for the treatment of Hypertension. Synonyms: CGP-42454A; CGP 42454A; CGP42454A; UNII-15B0UK1949; 2-((R)-3-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetic acid. Grade: 98%. CAS No. 131064-74-9. Molecular formula: C24H28N2O5. Mole weight: 424.49.
CGP 43182
CGP 43182, a dioxaspiro compound, has been found to a IIA sPLA2 inhibitor that could have potential anti-inflammatory effect and also in influencing the synergistic effect brought by pro-inflammatory genes. Synonyms: Cgp 43182; Cgp-43182; Cgp43182. N-(2,3-Dichlorophenyl)-2-hydroxy-4-oxo-1,5-dioxaspiro(5.5)undec-2-ene-3-carboxamide; N-(2,3-dichlorophenyl)-2-hydroxy-4-oxo-1,5-dioxaspiro[5.5]undec-2-ene-3-carboxamide; AC1L2SHN; DTXSID00164535. Grade: 98%. CAS No. 150379-37-6. Molecular formula: C16H15Cl2NO5. Mole weight: 372.20.
CGP 43487
CGP 43487 has been found to be a NMDA receptor antagonist and was once studied about its influenment of dopaminergic function as a supplement in the treatment of Parkinson's disease. Synonyms: Cgp 43487; Cgp43487; Cgp-43487; [(E,4R)-4-amino-5-ethoxy-2-methyl-5-oxopent-2-enyl]phosphonic acid. Grade: 98%. CAS No. 146388-56-9. Molecular formula: C8H16NO5P. Mole weight: 237.19.
Cgp 43902A
Cgp 43902A is a bio-active molecular, but no detailed information has been published yet. Synonyms: Cgp 43902A; Cgp43902A; Cgp-43902A. ethyl 2-[(4Z)-5-(hydroxymethyl)-2-methyl-3-oxo-4-[(2-pyridin-2-ylhydrazinyl)methylidene]pyridin-1-ium-1-yl]acetate; bromide. Grade: 98%. CAS No. 124076-31-9. Molecular formula: C17H21BrN4O4. Mole weight: 425.28.
Cgp 45688
Cgp 45688 is an non-steroidal aromatase inhibitor originated byNovartis. It has anti-tumor effects, but no development for treatment of cancer was reported. Uses: Cancer. Synonyms: Cgp 45688; Cgp45688; Cgp-45688. 4,4'-(2H-tetrazol-2-ylmethylene)bis-Benzonitrile. Grade: 98%. CAS No. 134520-88-0. Molecular formula: C16H10N6. Mole weight: 286.30.
CGP 46381
CGP 46381 is a selective GABAB receptor antagonist (IC50 = 4.9 μM). Synonyms: (3-Aminopropyl)(cyclohexylmethyl)phosphinic Acid; P-(3-Aminopropyl)-P-(cyclohexylmethyl)phosphinic Acid. CAS No. 123691-14-5. Molecular formula: C10H22NO2P. Mole weight: 219.26.
CGP 47072
CGP 47072, a bisphosphonate derivative, has been found to be a calcium regulator and was once studied in the treatment of osteoporosis. Synonyms: Cgp 47072; Cgp47072; Cgp-47072.CHEMBL101886; AC1L4IPT; SCHEMBL7164644; [1-hydroxy-3-[methyl(3-phenoxypropyl)amino]-1-phosphonopropyl]phosphonic acid. Grade: 98%. CAS No. 158859-42-8. Molecular formula: C13H23NO8P2. Mole weight: 383.27.
Cgp 47645
Cgp 47645 is non-steroidal aromatase inhibitor with anti-tumor and endocrine effects. It is orally active. Uses: Anti-tumor. Synonyms: Cgp 47645; Cgp47645; Cgp-47645; Leflutrozole; UNII-RCX0IE6EJZ; 4,4'-(fluoro-1H-1,2,4-triazol-1-ylmethylene)bis-Benzonitrile. Grade: 98%. CAS No. 143030-47-1. Molecular formula: C17H10FN5. Mole weight: 303.30.
CGP 48369
Cgp 48369 is a nonpeptide a angiotensin type 1 receptor antagonist originated by Novartis. Treatmenf for for Hypertension in Switzerland was discontinued in 1995. Uses: Hypertension. Synonyms: Cgp 48369; Cgp48369; Cgp-48369. 5-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2,6-dibutylpyrimidin-4(1H)-one. Grade: 98%. CAS No. 135689-23-5. Molecular formula: C26H30N6O. Mole weight: 442.56.
CGP52411
CGP52411, also known as DAPH, is a selective inhibitor of the epidermal growth factor receptor (EGFR). It is also inhibits and reverses the formation of Aβ42 fibers associated with Alzheimer's disease. It may offer therapeutic agents for the treatment of hyperproliferative diseases. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CGP52411; CGP 52411; CGP-52411; DAPH. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 145915-58-8. Molecular formula: C20H15N3O2. Mole weight: 329.36. Purity: >98%. IUPACName: 5,6-bis(phenylamino)isoindoline-1,3-dione. Canonical SMILES: O=C1NC(C2=CC(NC3=CC=CC=C3)=C(C=C21)NC4=CC=CC=C4)=O. Product ID: ACM145915588-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: 4,5-dianilinophthalimide.