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| Product | Description | |
|---|---|---|
| cembrene C synthase | Requires Mg2+. Isolated from the bacterium Streptomyces sp. SANK 60404. This bifunctional enzyme also produces (R)-nephthenol. See EC 4.2.3.149, nephthenol synthase. Group: Enzymes. Synonyms: DtcycA (gene name). Enzyme Commission Number: EC 4.2.3.148. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5162; cembrene C synthase; EC 4.2.3.148; DtcycA (gene name). Cat No: EXWM-5162. |  |
| Cement Alumina 65997-16-2 | Cement Alumina - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. |  North America & APAC |
| Cement White 65997-15-1 | Cement White - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. | North America & APAC |
| Cemiplimab | Cemiplimab is a PD-1 monoclonal antibody that blocks PD-1/PD-L1-mediated T-cell suppression. Cemiplimab has been approved for the treatment of metastatic cutaneous squamous cell carcinoma (CSCC). Synonyms: Libtayo. CAS No. 1801342-60-8. |  |
| Cemiplimab | Cemiplimab (Anti-Human PD-1) is a high-affinity programmed death receptor-1 ( PD-1 ) monoclonal IgG4 antibody that blocks PD-1/PD-L1-mediated T-cell suppression. Cemiplimab is commonly used in squamous cell skin cancer research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1801342-60-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99203. |  |
| CeMMEC1 | CeMMEC1 is an N-methylisoquinolinone derivative that inhibits the second bromodomain of TAF1 (Kd = 1.8 μM; IC50 = 0.9 μM). It does not bind to either the first or second bromodomain of BRD4. CeMMEC1 can also inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells. Synonyms: CeMMEC1; 440662-09-9; N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide; N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methyl-1-oxoisoquinoline-4-carboxamide; Oprea1_520920; SCHEMBL20942542; BCP19839; EX-A1815; EiM08-22966; AKOS005754739; AC-35499; MS-25094; HY-111445; CS-0040872; Z1863671528; N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-2-METHYL-1-OXO-1,2-DIHYDRO-4-ISOQUINOLINECARBOXAMIDE. Grades: ≥98%. CAS No. 440662-09-9. Molecular formula: C19H16N2O4. Mole weight: 336.3. | |
| CeMMEC13 | CeMMEC13 is an isoquinolinone and a potent inhibitor of TAF1 bromodomain with IC50 of 2.1 μM. It acts on the bromodomain of TAF1 but does not bind to bromodomains of BRD4, BRD9, or CREBBP. CeMMEC13 synergizes with (+)-JQ1 to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells. Synonyms: CeMMEC13; 1790895-25-8; 1-Methyl-2-oxo-1,2-dihydro-quinoline-4-carboxylic acid (2,3-dihydro-benzo[1,4]dioxin-6-yl)-amide; N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1-methyl-2-oxo-1,2-dihydroquinoline-4-carboxamide; CHEMBL4871450; N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-methyl-2-oxoquinoline-4-carboxamide; SCHEMBL20942221; BCP25037; EX-A1816; BDBM50572136; s8329; AKOS027600530; CeMMEC13, >=98% (HPLC); CCG-267868; AC-35506; BS-15617; HY-101088; CS-0020799; C73404; A924884; Z441586532; N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,2-dihydro-1-methyl-2-oxo-4-quinolinecarboxamide. Grades: ≥98%. CAS No. 1790895-25-8. Molecular formula: C19H16N2O4. Mole weight: 336.3. | |
| CeMMEC1 hydrochloride | CeMMEC1 is an N-methylisoquinolinone derivative that inhibits the second bromodomain of TAF1 (Kd = 1.8 μM; IC50 = 0.9 μM). It does not bind to either the first or second bromodomain of BRD4. CeMMEC1 can also inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells. Synonyms: CeMMEC1 HCl. Grades: ≥98%. CAS No. 2095432-53-2. Molecular formula: C19H17ClN2O4. Mole weight: 372.8. | |
| Cemsidomide | Cemsidomide (CFT7455) is a ubiquitin ligase pathway Ikaros / Aiolos degrader with molecular glue activity [1]. Cemsidomide has a GI 50 of 0.05 nM for NCIH929.1 cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CFT7455. CAS No. 2504235-67-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144841. | |
| Cendakimab | Cendakimab (RPC4046; ABT 308; CC-93538) is a selective, humanized, recombinant monoclonal antibody against the IL-13 molecule. Cendakimab has a high affinity and potency for both human wild-type and variant IL-13 and blocks binding of IL-13 to both IL-13Rα1 and IL-13Rα2 with IC 50 s of 352 pM and 631 pM by ELISA, respectively. Cendakimab recognizes both wild-type human IL-13 and the common polymorphic variant R110Q, with binding affinities of 52 and 50 pM, respectively. Cendakimab has the potential for IL-13-related allergic/inflammatory diseases (e.g., asthma and eosinophilic esophagitis) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: RPC 4046; ABT 308; CC-93538. CAS No. 2151032-62-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99496. | |
| Cenderitide | Cenderitide is a potent agonist of particulate guanylyl cyclase receptor (pGC). Cenderitide is a natriuretic peptide (NP) composed of C-type natriuretic peptide (CNP) fused to the C-terminus of Dendroaspis natriuretic peptide (DNP). Cenderitide activates both pGC-A and pGC-B , activates the second messenger cGMP , suppresses aldosterone , and preserves GFR without reducing blood pressure. Cenderitide can be used for heart failure research [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 507289-11-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3624. | |
| Cenegermin | Cenegermin is a recombinant human nerve growth factor that has the healing effect on eye and repair corneal damage. It was granted orphan drug designation in 2015. Uses: Repair corneal damage. CAS No. 1772578-74-1. Molecular formula: C583H908N166O173S8. Mole weight: 13266.94. | |
| Cenerimod | Cenerimod (ACT-334441) is a potent, selective and orally active S1P1 receptor modulator, with an EC 50 of 1 nM. Cenerimod shows more than 36 fold selctivity for hS1P1 over hS1P2, hS1P3, hS1P4, and hS1P5 receptor subtypes (EC 50 s=>10000, 228, 2134, and 36 nM, respectively). Cenerimod can attenuate murine experimental autoimmune encephalomyelitis (EAE) and murine sclerodermatous [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACT-334441. CAS No. 1262414-04-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17606. | |
| Cenerimod | Cenerimod is an active Lysosphingolipid receptor agonist originated by Actelion Pharmaceuticals and EC50 value is 2.7 nM. It is a S1P1/EDG1 receptor agonist and has a long-lasting immunomodulating effect through reducing the number of circulating and infiltrating T- and B-lymphocytes, without affecting their maturation, memory, or expansion. Cenerimod is in phase I/II clinical trials for the treatment of Systemic lupus erythematosus. Uses: Systemic lupus erythematosus. Synonyms: ACT-334441; ACT334441; ACT 334441; (S)-3-(4-(5-(2-cyclopentyl-6-methoxypyridin-4-yl)-1,2,4-oxadiazol-3-yl)-2-ethyl-6-methylphenoxy)propane-1,2-diol. Grades: 98%. CAS No. 1262414-04-9. Molecular formula: C25H31N3O5. Mole weight: 453.54. | |
| Cenicriviroc | Cenicriviroc (TAK-652) is an orally active, dual CCR2/CCR5 antagonist, also inhibits both HIV-1 and HIV-2, and displays potent anti-inflammatory and antiinfective activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Cenicriviroc;TAK652. Product Category: Inhibitors. CAS No. 497223-25-3. Mole weight: 0. Purity: 0.9901. Product ID: ACM497223253. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Cenicriviroc | Cenicriviroc (TAK-652) is an orally active, dual CCR2/CCR5 antagonist, also inhibits both HIV-1 and HIV-2, and displays potent anti-inflammatory and antiinfective activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-652; TBR-652. CAS No. 497223-25-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14882. | |
| Cenicriviroc | Cenicriviroc is an inhibitor of CCR2 and CCR5 receptors, allowing it to function as an entry inhibitor which prevents the virus from entering into a human cell as an experimental drug candidate for the treatment of HIV infection. Uses: Ccr2 receptor antagonists; ccr5 receptor antagonists. Synonyms: (S,E)-8-(4-(2-Butoxyethoxy)phenyl)-1-isobutyl-N-(4-(((1-propyl-1H-imidazol-5-yl)methyl)sulfinyl)phenyl)-1,2,3,4-tetrahydrobenzo[b]azocine-5-carboxamide; TAK-652; TAK652; TAK 652; TBR-652; TBR 652; TBR652; Cenicriviroc. Grades: ≥98%. CAS No. 497223-25-3. Molecular formula: C41H52N4O4S. Mole weight: 696.95. | |
| Cenicriviroc mesylate | Cenicriviroc is an inhibitor of CCR2 and CCR5 receptors, allowing it to function as an entry inhibitor which prevents the virus from entering into a human cell as an experimental drug candidate for the treatment of HIV infection. Synonyms: TAK-652 mesylate; TAK 652 mesylate; TBR-652 mesylate; TBR 652 mesylate. Grades: 99.04%. CAS No. 497223-28-6. Molecular formula: C42H56N4O7S2. Mole weight: 793.051. | |
| Cenicriviroc Mesylate | Cenicriviroc Mesylate (TAK-652 Mesylate) is a dual CCR2/CCR5 antagonist, also inhibits both HIV-1 and HIV-2, and displays potent anti-inflammatory and antiinfective activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-652 Mesylate; TBR-652 Mesylate. CAS No. 497223-28-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14882A. | |
| Cenicriviroc Sulfone | Cenicriviroc Sulfone is a derivative of Cenicriviroc which is an experimental drug candidate for the treatment of HIV infection. It is an inhibitor of CCR2 and CCR5 receptors, allowing it to function as an entry inhibitor which prevents the virus from entering into a human cell. Synonyms: 8-[4-(2-Butoxyethoxy)phenyl]-1,2,3,4-tetrahydro-1-(2-methylpropyl)-N-[4-[[(1-propyl-1H-imidazol-5-yl)methyl]sulfonyl]phenyl]-1-benzazocine-5-carboxamide; 8-[4-(2-Butoxyethoxy)phenyl]-1-isobutyl-N-[4-[[(1-propyl-1H-imidazol-5-yl)methyl]sulfonyl]phenyl]-1. Grades: > 95%. CAS No. 497223-22-0. Molecular formula: C41H52N4O5S. Mole weight: 712.96. | |
| CENP-F Antibody Panel, CENP-F (aa3150-3200) Control Peptide | CENP-F Antibody Panel, CENP-F (aa3150-3200) Control Peptide. Group: Molecular Biology. Grades: Affinity Purified. Pack Sizes: 1x100ul. US Biological Life Sciences. |  Worldwide |
| Censavudine | Censavudine is a nucleoside reverse transcriptase inhibitor. It is active against HIV resistant to both abacavir and tenofovir. It is a candidate for people with multi-drug resistant (MDR) strains of the virus. It is a derivative of stavudine (d4T), but is less toxic. It has demonstrated potent in vitro activity against HIV-2. It was developed by Bristol Myers-Squibb and in clinic phase 2 trials. Uses: Censavudine is active against hiv resistant to both abacavir and tenofovir. Synonyms: OBP-601; OBP601; OBP 601; BMS-986001; BMS 986001; BMS986001; festinavir; 4'-Ed4T; Censavudine; 2',3'-Didehydro-3'-deoxy-4'-ethynylthymidine;4'-Ed4T;4'-Ethynylstavudine;4'-Ethynyl D4T;1-[(2R,5R)-5-ethynyl-5-(hydroxymethyl)-2H-furan-2-yl]-5-methylpyrimidine-2,4-dione. Grades: 98%. CAS No. 634907-30-5. Molecular formula: C12H12N2O4. Mole weight: 248.24. | |
| Centanafadine | Centanafadine is dual norepinephrine (NE)/dopamine (DA) transporter inhibitor, also inhibits serotonin transporter, with IC 50 s of 6 nM, 38 nM and 83 nM for human NE, DA and serotonin transporter , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EB-1020. CAS No. 924012-43-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16736. | |
| Centanafadine hydrochloride | Centanafadine (hydrochloride) is dual norepinephrine (NE)/dopamine (DA) transporter inhibitor, also inhibits serotonin transporter, with IC 50 s of 6 nM, 38 nM and 83 nM for human NE, DA and serotonin transporter , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EB-1020 hydrochloride. CAS No. 923981-14-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16736A. | |
| Centanafadine Lactam | Centanafadine Lactam is an impurity or metabolite of Centanafadine, which is a dual norepinephrine-dopamine transporter inhibitor used in the treatment of Attention Deficit Hyperactivity Disorder (ADHD). Synonyms: (1S,5R)-5-(2-Naphthyl)-3-azabicyclo[3.1.0]hexan-2-one; 3-Azabicyclo[3.1.0]hexan-2-one, 5-(2-naphthalenyl)-, (1S,5R)-. Molecular formula: C15H13NO. Mole weight: 223.27. | |
| Centaurein | Centaurein. Uses: Designed for use in research and industrial production. Additional or Alternative Names: centaurein;2-(3-Hydroxy-4-methoxyphenyl)-3,6-dimethoxy-4-oxo-5-hydroxy-4H-1-benzopyran-7-yl β-D-glucopyranoside;3,6,4'-Trimethoxy-5,3'-dihydroxy-7-(β-D-glucopyranosyloxy)flavone;7-(β-D-Glucopyranosyloxy)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6-dimeth. Product Category: Heterocyclic Organic Compound. CAS No. 35595-03-0. Molecular formula: C24H26O13. Mole weight: 522.456. Product ID: ACM35595030. Alfa Chemistry ISO 9001:2015 Certified. Categories: Centaurin, alpha 1. | |
| Centella Asiatica Extract | Centella asiatica extract is prepared from a small herbaceous annual plant of the family mackinlayaceae, which native to India, Sri Lanka, China, and other parts of Asia. The main active ingredient of centella asiatica extract, also known as gotu kola extract is asiaticoside and asiatic acid. Centella asiatica extract is widely used to heal wounds, treat skin conditions, improve mental clarity, treat varicose veins and chronic venous insufficiency. Group: Others. Mole weight: 959.12. Centella Asiatica Extract; Centella Asiatica (Linn.) Urban. Cat No: EXTC-024. | |
| Centella Asiatica Extract | diminish inflammation, pore cleanser, emulsifying; suitable for any skin. Uses: Designed for use in research and industrial production. Product Category: Material of cosmetics. Appearance: brown yellow to white fine powder. CAS No. 84696-21-9. Product ID: ACM84696219. Alfa Chemistry ISO 9001:2015 Certified. | |
| Centhaquin | Centhaquine (Centhaquin; PMZ-2010) is a novel agent has the potential for treatment of haemorrhagic shock. Centhaquine (Centhaquin; PMZ-2010) can augment cardiac output, reduce systemic vascular resistance in haemorrhagic models [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Centhaquine; PMZ-2010. CAS No. 57961-90-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106690. | |
| Centhaquine | Centhaquin is a new type of drug with the potential to treat hemorrhagic shock. Synonyms: Centhaquin; Compound-7173; PMZ-2010; PMZ-2010. Grades: 98%. CAS No. 57961-90-7. Molecular formula: C22H25N3. Mole weight: 331.5. | |
| Centifolether | Centifolether. CAS No. 120811-92-9. VIGON Item # 504884. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. |  America & Internationally |
| Centrinone | Centrinone, a pyrimidinamine derivative, has been found to be a high affinity and selective PLK4 inhibitor (Ki = 0.16 nM). Synonyms: Centrinone; LCR-263; LCR 263; LCR263. 2-[[2-Fluoro-4-[[ (2-fluoro-3-nitrophenyl) methyl]sulfonyl]phenyl]thio]-5-methoxy-N- (5-methyl-1H-pyrazol-3-yl) -6- (4-morpholinyl) -4-pyrimidinamine. Grades: ≥98% by HPLC. CAS No. 1798871-30-3. Molecular formula: C26H25F2N7O6S2. Mole weight: 633.65. | |
| Centrinone B | Centrinone B, has been found to be a high affinity and selective PLK4 inhibitor (Ki: 0.6 nM) and exhibit more than 2000-fold selectivity for PLK4 over Aurora A and Aurora B. Synonyms: Centrinone-B; Centrinone B; CentrinoneB; LCR-323; LCR 323; LCR323; 2-[[2-Fluoro-4-[[ (2-fluoro-3-nitrophenyl) methyl]sulfonyl]phenyl]thio]-5-methoxy-N- (5-methyl-1H-pyrazol-3-yl) -6- (1-piperidinyl) -4-pyrimidinamine. Grades: ≥98% by HPLC. CAS No. 1798871-31-4. Molecular formula: C27H27F2N7O5S2. Mole weight: 631.67. | |
| Centrocin 1 | Centrocin 1 is isolated from Strongylocentrotus droebachiensis. It has antimicrobial activity against Gram-negative bacteria, Gram-positive bacteria and against fungi with minimum inhibitory concentration (MIC) between 0.78 μM and 50 μM. Centrocin 1 shows little hemolytic activity even at a concentration of 100 μM. | |
| Centrocin 2 | Centrocin 2 is isolated from Strongylocentrotus droebachiensis. It has antimicrobial activity against Gram-negative bacteria, Gram-positive bacteria and against fungi with minimum inhibitory concentration (MIC) between 0.78 μM and 50 μM. Centrocin 2 shows little hemolytic activity at concentrations up to 12.5 μM but >50% lysis at 100 μM. | |
| Centrophenoxine 98% HPLC | Centrophenoxine 98% HPLC. |  CA, FL & NJ |
| Centrophenoxine HCL | Centrophenoxine HCL. Categories: meclofenoxate hydrochloride; 3685-84-5. | CA, FL & NJ |
| CeO2 | CeO2. Group: Nano rare-earth materials. 99.95% (REO). |  |
| CeO2 Nanoparticles | CeO2 Nanoparticles. Group: Oxides nanoparticles. 99.99%. | |
| CEP-11981 | CEP-11981 is an orally bioavailable inhibitor of vascular endothelial growth factor receptor (VEGFR) and Tie2 receptor tyrosine kinases with potential antiangiogenic and antineoplastic activities. Pan-VEGFR/Tie2 tyrosine kinase inhibitor CEP-11981 selectively binds to VEGFR and Tie2 receptor tyrosine kinases, which may result the inhibition of endothelial cell migration, proliferation and survival and the inhibition of tumor cell proliferation and tumor cell death. VEGFR and Tie2 are frequently overexpressed by a variety of tumor cell types and play crucial roles in the regulation of angiogenesis and the maintenance of tumor blood vessels. Tie2 (tyrosine kinase with immunoglobulin-like and EGF-like domains) is activated by angiopoietin-1 (Ang-1). Synonyms: CEP-11981; CEP 11981; CEP11981. CAS No. 856691-93-5. Molecular formula: C28H27N7O. Mole weight: 477.57. | |
| CEP 1347 | CEP 1347, also named KT 7515 or CHEMBL290352, an ethylthiomethyl derivative, is a potent, selective inhibitor of the cJun-amino terminal kinase pathway currently under clinical evaluation for the treatment of neurodegenerative diseases. It blocks Aβ-induced cortical neuron apoptosis (EC50 ~51 nM). Uses: Anti-alzheimer agents; amyloid-β inhibitor. Synonyms: CHEMBL290352; CEP-1347; 3,9-Bis(etsm)-K-252a; CEP1347; 156177-65-0; CEP 1347; KT7515; 3,9-Bis((ethylthio)methyl)-K-252a; KT 7515; KT-7515; GTPL8173; SCHEMBL12047710; BDBM24942; CEP1374; CEP 1374; CEP-1374; ZINC3928304; AKOS024458422; KT-1575; 170587-65-2; 9,12-Epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-10-carboxylic acid, 5,16-bis((ethylthio)methyl)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-, methyl ester, (9S-(9alpha,10beta,12alpha))-; CEP 1347|(9S,10R,12R)-5-16-Bis[(ethylthio)methyl]-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester; methyl (15S, 16R, 18R)-10, 23-bis[(ethylsulfanyl)methyl]-16-hydroxy-15-methyl-3-oxo-28-oxa-4, 14, 19-triazaoctacyclo[12.11.2.1^{15, 18}.0^{2, 6}.0^{7, 27}.0^{8, 13}.0^{19, 26}.0^{20, 25}]octacosa-1, 6, 8, 10, 12, 20, 22, 24, 26-nonaene-16-carboxylate. CAS No. 156177-65-0. Molecular formula: C33H33N3O5S2. Mole weight: 615.76. | |
| CEP 1347 | Inhibitor of c-jun N-terminal kinase (JNK) signaling. Rescues motor neurons undergoing apoptosis (EC50 = 20nM). Blocks A β-induced cortical neuron apoptosis (EC50 ~51nM). Does not inhibit ERK1 activity. Neuroprotective. Group: Biochemicals. Alternative Names: (9S,10R,12R)-5-16-Bis[(ethylthio)methyl]-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester. Grades: Highly Purified. CAS No. 156177-65-0. Pack Sizes: 1mg. Molecular Formula: C33H33N3O5S2.1?2H2O, Molecular Weight: 624.77. US Biological Life Sciences. | Worldwide |
| CEP-1347 | CEP-1347 is an inhibitor of the JNK/SAPK pathway with neuroprotective effects. CEP-1347 blocks JNK1 activation induced by members of the mixed lineage kinase (MLK) family (MLK3, MLK2, MLK1, dual leucine zipper kinase, and leucine zipper kinase). As an inhibitor of MDM4 , CEP-1347 can more effectively inhibit the growth of glioma cells expressing wild-type p53 [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KT7515. CAS No. 156177-65-0. Pack Sizes: 1 mg. Product ID: HY-10412. | |
| CEP-14083 | CEP-14083 is a ALK inhibitor. It has a potent activity against ALK in enzymatic assays (IC50 = 11 nmol/L). CEP-14083 can also inhibit the insulin receptor at a concentration within a nanomolar range. In a preclinical assay, CEP-14083 showed it can control the expression of molecules that determine T-cell identity and signaling in lymphoma cells. Synonyms: CEP14083; CEP 14083; CEP-14083. 1-methyl-3-(4-methyl-6-oxo-13-propyl-2,4,6,7,8,13-hexahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-10-yl)-1-phenylurea. Grades: 98%. CAS No. 856692-39-2. Molecular formula: C31H30N6O2. Mole weight: 518.61. | |
| CEP-14513 | CEP-14513 is a ALK inhibitor. It shows ALK inhibitory activity in both in vitro enzymatic assay (IC50 = 5 nM) and cell-based assays of ALK tyrosine phosphorylation (IC50 = 30 nM). Synonyms: CEP14513; CEP 14513; CEP-14513. 13-isobutyl-4-methyl-6-oxo-2,4,6,7,8,13-hexahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-10-yl 4-(dimethylamino)benzylcarbamate. Grades: 98%. CAS No. 856693-04-4. Molecular formula: C34H36N6O3. Mole weight: 576.69. | |
| CEP-1612 | CEP-1612, a dipeptidyl proteasome inhibitor, induces apoptosis and inhibits tumor growth of the human lung cancer cell line A-549 in an in vivo model. Synonyms: N-[(2S)-5-[[amino(nitramido)methylidene]amino]-1-[[(2S)-4-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]-2-cyclopentyl-10-(1,3-dioxoisoindol-2-yl)decanamide; CEP-1612; CEP 1612; CEP1612; UNII-9K6U075027. Grades: >98%. CAS No. 189036-01-9. Molecular formula: C35H53N7O7. Mole weight: 683.84. | |
| CEP-28122 | CEP-28122 is a highly potent and selective oral anaplastic lymphoma kinase inhibitor with antitumor activity in experimental human cancer models. Synonyms: CEP 28122; CEP28122; Bicyclo[2.2.1]hept-5-ene-2-carboxamide, 3-[[5-chloro-2-[[(7S)-6,7,8,9-tetrahydro-1-methoxy-7-(4-morpholinyl)-5H-benzocyclohepten-2-yl]amino]-4-pyrimidinyl]amino]-, (1S,2S,3R,4R)-; (1S,2S,3R,4R)-3-[[5-Chloro-2-[[(7S)-6,7,8,9-tetrahydro-1-methoxy-7-(4-morpholinyl)-5H-benzocyclohepten-2-yl]amino]-4-pyrimidinyl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide. Grades: ≥95%. CAS No. 1022958-60-6. Molecular formula: C28H35ClN6O3. Mole weight: 539.07. | |
| CEP-32496 | CEP-32496 is a highly potent inhibitor of BRAF(V600E/WT) and c-Raf with Kd of 14 nM/36 nM and 39 nM, also potent to Abl-1, c-Kit, Ret, PDGFRβ and VEGFR2, respectively; insignificant affinity for MEK-1, MEK-2, ERK-1 and ERK-2. Phase 1/2. Synonyms: 1-(3-((6,7-dimethoxyquinazolin-4-yl)oxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea; RXDX-105; RXDX 105; RXDX105; CEP32496; CEP-32496; CEP 32496; AC013773; AC 013773; AC-013773 Agerafenib. Grades: >98%. CAS No. 1188910-76-0. Molecular formula: C24H22F3N5O5. Mole weight: 517.46. | |
| CEP-32496 hydrochloride | CEP-32496, also known as AC013773, is an orally available v-raf murine sarcoma viral oncogene homolog B1 (B-raf) serine/threonine protein kinase inhibitor with potential antineoplastic activity. CEP-32496 specifically and selectively inhibits the activity of the mutated form (V600E) of B-raf kinase. This inhibits the activation of the RAF/mitogen-activated protein kinase kinase (MEK)/extracellular signal-related kinase (ERK) signaling pathway and may result in a decrease in the proliferation of tumor cells expressing the mutated B-raf gene. The Raf mutation BRAF V600E, in which valine is substituted for glutamic acid at residue 600, is frequently found in a variety of human tumors and results in the constitutive activation of the RAF/MEK/ERK signaling pathway that regulates cellular proliferation and survival. Synonyms: CEP-32496; CEP32496; CEP 32496; AC013773; AC 013773; AC-013773. CAS No. 1227678-26-3. Molecular formula: C24H23ClF3N5O5. Mole weight: 553.92. | |
| CEP33779 | CEP-33779 is a highly selective, orally active inhibitor of JAK2. It induces regression of established colorectal tumors, angiogenesis, and proliferation of tumor cells. Synonyms: CEP-33779; N-[3-(4-methylpiperazin-1-yl)phenyl]-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine. Grades: >98%. CAS No. 1257704-57-6. Molecular formula: C24H26N6O2S. Mole weight: 462.572. | |
| CEP-37440 | CEP-37440 is an orally available dual kinase inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) and focal adhesion kinase (FAK), with potential antineoplastic activity. Upon administration, ALK-FAK inhibitor CEP-37440 selectively binds to and inhibits ALK kinase and FAK kinase. The inhibition leads to disruption of ALK- and FAK-mediated signal transduction pathways and eventually inhibits tumor cell growth in ALK- and FAK-overexpressing tumor cells. ALK belongs to the insulin receptor superfamily and plays an important role in nervous system development; its dysregulation and gene rearrangements are associated with a variety of tumors. The cytoplasmic tyrosine kinase FAK, a signal transducer for integrins, is upregulated and constitutively activated in various tumor types; it plays a key role in tumor cell migration, proliferation, survival, and tumor angiogenesis. Synonyms: CEP-37440; CEP 37440; CEP37440. CAS No. 1391712-60-9. Molecular formula: C30H38ClN7O3. Mole weight: 580.12. | |
| CEP-40783 | CEP-40783 is an orally-active, nanomolar potent and highly kinase-selective Type II inhibitor of the AXL and c-Met RTK with IC50 values of 7 nM and 12 nM, respectively. Synonyms: N-[4-(6,7-dimethoxyquinolin-4-yl)oxy-3-fluorophenyl]-3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide; CEP40783; CEP 40783; CEP-40783; RXDX-106; RXDX 106; RXDX106. CAS No. 1437321-24-8. Molecular formula: C31H26F2N4O6. Mole weight: 588.56. | |
| CEP-5214 | CEP-5214 is a potent, low-nanomolar pan inhibitor of human VEGF-R tyrosine kinases, displaying IC(50) values of 16, 8, and 4 nM for VEGF-R1/FLT-1, VEGF-R2/KDR, and VEGF-R3/FLT-4, respectively, with cellular activity equivalent to the isolated enzyme activity. Compound 21 exhibited good selectivity against numerous tyrosine and serine/threonine kinases including PKC, Tie2, TrkA, CDK1, p38, JNK, and IRK. Synonyms: CEP 5214; CEP5214; 3-(5,6,7,13-tetrahydro-9-((1-methylethoxy)methyl)-5-oxo-12h-indeno(2,1-a)pyrrolo(3,4-c)carbazol-12-yl)propanol; 12-(3-hydroxypropyl)-9-isopropoxymethyl-6,7,12,13-tetrahydro-5H-indeno[2,1-a]pyrrolo[4,3-c]carbazol-5-one. CAS No. 402857-39-0. Molecular formula: C28H28N2O3. Mole weight: 440.54. | |
| CEP-6800 | CEP-6800 is a potent PARP inhibitor with potential anticancer activity. CEP-6800 could be used as a chemopotentiating agent with a variety of clinically effective chemotherapeutic agents. Synonyms: CEP 6800; CEP6800; 10-(aminomethyl)-4,5,6,7-tetrahydro-1H-cyclopenta[a]pyrrolo[3,4-c]carbazole-1,3(2H)-dione; 8-aminomethyl-1,2,3,11-tetrahydro-5,11-diaza-benzo[a]trindene-4,6-dione. Grades: 98%. CAS No. 609848-02-4. Molecular formula: C18H15N3O2. Mole weight: 305.34. | |
| CEP-7055 | CEP-18770 is An orally bioavailable synthetic P2 threonine boronic acid inhibitor of the chymotrypsin-like activity of the proteasome, with potential antineoplastic activity. Proteasome inhibitor CEP 18770 represses the proteasomal degradation of a variety of proteins, including inhibitory kappaBalpha (IkappaBalpha), resulting in the cytoplasmic sequestration of the transcription factor NF-kappaB; inhibition of NF-kappaB nuclear translocation and transcriptional up-regulation of a variety of cell growth-promoting factors; and apoptotic cell death in susceptible tumor cell populations. In vitro studies indicate that this agent exhibits a favorable cytotoxicity profile toward normal human epithelial cells, bone marrow progenitors, and bone marrow-derived stromal cells relative to the proteasome inhibitor bortezomib. The intracellular protein IkappaBalpha functions as a primary inhibitor of the proinflammatory transcription factor NF-kappaB. Synonyms: CEP 7055; CEP7055; 3-(9-isopropoxymethyl-5-oxo-6,7,12,13-tetrahydro-5H-indeno[2,1-a]pyrrolo[4,3-c]carbazol-12-yl)propyl 2-dimethylaminoacetate. CAS No. 402857-58-3. Molecular formula: C32H35N3O4. Mole weight: 525.65. | |
| CEP-9722 | CEP-9722 is a small-molecule prodrug of CEP-8983, a novel 4-methoxy-carbazole inhibitor of the nuclear enzymes poly(ADP-ribose) polymerase (PARP) 1 and 2, with potential antineoplastic activity. Upon administration and conversion from CEP-9722, CEP-8983 selectively binds to PARP 1 and 2, preventing repair of damaged DNA via base excision repair (BER). This agent enhances the accumulation of DNA strand breaks and promotes genomic instability and apoptosis. CEP-8983 may potentiate the cytotoxicity of DNA-damaging agents and reverse tumor cell chemo- and radioresistance. PARP catalyzes post-translational ADP-ribosylation of nuclear proteins that signal and recruit other proteins to repair damaged DNA and can be activated by single strand breaks in DNA. Synonyms: CEP 9722; CEP9722; 11-methoxy-2-((4-methylpiperazin-1-yl)methyl)-4,5,6,7-tetrahydro-1H-cyclopenta[a]pyrrolo[3,4-c]carbazole-1,3(2H)-dione. CAS No. 916574-83-9. Molecular formula: C24H26N4O3. Mole weight: 418.49. | |
| Cepabactin | Cepabactin is an antibiotic produced by Pseudomonas sp. BN-227. It has anti-gram-positive and negative bacteria activity. Synonyms: Antibiotic BN 227; BN 227; Antibiotic G 1549; 1-Hydroxy-5-methoxy-6-methyl-2(1H)-pyridinone. CAS No. 72731-33-0. Molecular formula: C7H9NO3. Mole weight: 155.15. | |
| Cepacidin A | Cepacidin A is an antifungal cyclic peptide antibiotic produced by Pseudomonas cepacia AF 2001. Synonyms: 2-[25-amino-22-(2-amino-1-hydroxy-2-oxoethyl)-19-[6-amino-4-hydroxy-2-(3,4,5-trihydroxyoxan-2-yl)oxypentadecyl]-12-[hydroxy-(4-hydroxyphenyl)methyl]-6,15-bis(hydroxymethyl)-2,5,8,11,14,17,21,24-octaoxo-1,4,7,10,13,16,20,23-octazacycloheptacos-9-yl]acetic. CAS No. 157184-36-6. Molecular formula: C52H85N11O22. Mole weight: 1216.29. | |
| Cepacin A | It is produced by the strain of Pseudomonas cepacia SC 11783. It has anti-gram positive and negative bacterial activity. Synonyms: 2(3H)-Furanone, 4,5-dihydro-5-(3-hydroxy-4-oxododeca-1,6,7-trien-9,11-diynyl)-; 2(5H)-Furanone, 5-(3-(3-(1,2-heptadiene-4,6-diynyl)oxiranyl)-3-hydroxy-1-propenyl)dihydro-; 4,5-Dihydro-5-(3-hydroxy-4-oxododeca-1,6,7-trien-9,11-diynyl)-2(3H)-furanone. CAS No. 91682-95-0. Molecular formula: C16H14O4. Mole weight: 270.28. | |
| Cepacin B | It is produced by the strain of Pseudomonas cepacia SC 11783. It has anti-gram positive and negative bacterial activity. Synonyms: 4,5-Dihydro-5-(2,3:4,5-diepoxy-1-hydroxydodeca-6,7-dien-9,11-diynyl)-2(3H)-furanone; 2(5H)-Furanone, 5-((3'-(1,2-heptadiene-4,6-diynyl)(2,2'-bioxiran)-3-yl)hydroxymethyl)dihydro-; 2(3H)-Furanone, 4,5-dihydro-5-(2,3:4,5-diepoxy-1-hydroxydodeca-6,7-dien-9,11-diynyl)-; CEPACIN-B. CAS No. 91682-94-9. Molecular formula: C16H14O5. Mole weight: 286.28. | |
| Cepafungin I | Cepafungin I is an acyl peptide antibiotic produced by Pseudomonas sp. CB-3. It has activity against Candida, Aspergillus fumigatus and Trichophyton, but it is not effective against Candida albicans M-9 infection in mice. Synonyms: 2,4-Dodecadienamide, N-(2-hydroxy-1-(((10-hydroxy-5-methyl-2,7-dioxo-1,6-diazabicyclododec-3-en-8-yl)amino)carbonyl)propyl)-11-methyl-, (5S-(3E,5R*,8R*(1R*(2E,4E),2S*),10R*))-. CAS No. 130743-08-7. Molecular formula: C28H46N4O6. Mole weight: 534.67. | |
| Cepafungin III | Cepafungin III is an acyl peptide antibiotic produced by Pseudomonas sp. CB-3. It has activity against Candida, Aspergillus fumigatus and Trichophyton, but it is not effective against Candida albicans M-9 infection in mice. Synonyms: 2,4-Decadienamide, N-(2-hydroxy-1-(((10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl)amino)carbonyl)propyl)-9-methyl-, (SS-(3E,5R*,8R*(1R*(2E,4E),2S*),10R*))-. CAS No. 130743-09-8. Molecular formula: C26H42N4O6. Mole weight: 506.63. | |
| CEP dipeptide 1 | CEP dipeptide 1 is a CEP dipeptide which has potent angiogenic activity. It is used as mediators of age-related macular degeneration (AMD). Uses: Cep dipeptide 1 is used as mediators of age-related macular degeneration (amd). Synonyms: L-Norleucine, N-acetylglycyl-6-[2-(2-carboxyethyl)-1H-pyrrol-1-yl]-, methyl ester; (S)-3-(1-(5-(2-acetamidoacetamido)-6-methoxy-6-oxohexyl)-1H-pyrrol-2-yl)propanoic acid. Grades: >98%. CAS No. 816432-15-2. Molecular formula: C18H27N3O6. Mole weight: 381.42. | |
| Ceperognastat | Ceperognastat (LY3372689) is an orally active O-GlcNAcase (OGA) enzyme inhibitor. Ceperognastat can be used for tauopathies research, including Alzheimers disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY3372689. CAS No. 2241514-56-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144681. | |
| Cephabacin F1 | It is produced by the strain of Lysobacter lactamgenus YK-90, Xanthomonas lactamgena YK-278?YK-280 and YK-431. It has anti-gram positive and negative bacterial activity. The Cephabacin F series is stable and has inhibitory effect on cephalosporin enzyme. CAS No. 95041-98-8. Molecular formula: C26H41N9O11S. Mole weight: 687.72. | |
| Cephabacin M1 | It is produced by the strain of Lysobacter lactamgenus YK-90, Xanthomonas lactamgena YK-278?YK-280 and YK-431. It has anti-gram positive and negative bacterial activity. The Cephabacin M series is stable and has inhibitory effect on cephalosporin enzyme. CAS No. 99332-96-4. Molecular formula: C31H50N8O13S. Mole weight: 774.84. | |
| Cephabacin M6 | It is produced by the strain of Lysobacter lactamgenus YK-90, Xanthomonas lactamgena YK-278?YK-280 and YK-431. It has anti-gram positive and negative bacterial activity. The Cephabacin M series is stable and has inhibitory effect on cephalosporin enzyme. Synonyms: Cephabacin M(sub 6); L-Valinamide, L-alanyl-L-seryl-L-ornithyl-L-valyl-L-ornithyl-N-(4-((7-((5-amino-5-carboxyl-1-oxopentyl)amino)-2-carboxy-7-methoxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-3-en-3-yl)methoxy)-1-(2-amino-2-oxoethyl)-2-hydroxy-4-oxobutyl)-, (6R-(6-alpha,7-alpha,7(R*)))-; Cephabacin M6; LS-161269. CAS No. 99313-73-2. Molecular formula: C47H79N13O18S. Mole weight: 1146.27. | |
| Cephacetrile | It is produced by the strain of Semisynthetic first generation cephalosporin for injection. Its sodium salt is used in preparations. It has the first-generation cephalosporin commonness. It is characterized by the excretion of more than 90% of the dose in the urine within 24 hours, so it is especially suitable for urinary tract infection caused by sensitive bacteria. Synonyms: C 36278 Ba; C-36278-Ba; C36278Ba; Cephacetrile Sodium; Sodium, Cephacetrile; Celospor; Cefacetrilum; Cefacetrilo; Cefacetrile; (6R,7R)-3-Acetoxymethyl-7-(2-cyanacetamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeure; 7-(2-Cyanacetamido)-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carboxylat acetat (ester). Grades: 95%. CAS No. 10206-21-0. Molecular formula: C13H13N3O6S. Mole weight: 339.32. | |
| Cephaeline | Has been used as an emetic and expectorant. Group: Biochemicals. Alternative Names: (1R)-1-[[(2S,3R,11bS)-3-Ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-1,2,3,4-tetrahydro-7-methoxy-6-isoquinolinol; 7',10,11-Trimethoxyemetan-6'-ol; Cepheline; Desmethylemetine; (-)-Cephaeline. Grades: Highly Purified. CAS No. 483-17-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Cephaeline | Cephaeline is a phenolic alkaloid in Indian Ipecac roots. Cephaeline exhibits potent inhibition of both Zika virus (ZIKV) and Ebola virus (EBOV) infections. Uses: Designed for use in research and industrial production. Additional or Alternative Names: cephaeline;O-Phosphatidyl-ethanolamine;Cefalin;(-)-Cephaelin;(1R)-1-[[(2S,3R,11bS)-3-Ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-1,2,3,4-tetrahydro-7-methoxy-6-isoquinolinol;7,10,11-Trimethoxyemetan-6-ol;Cepheline;Desmethylemetine. Product Category: Inhibitors. Appearance: Off-White to Pale Yellow Solid. CAS No. 483-17-0. Molecular formula: C28H38N2O4. Mole weight: 466.61232. Purity: 0.9841. Canonical SMILES: OC1=CC2=C([C@@H](C[C@@H]3[C@@H](CC)CN4CCC5=CC(OC)=C(OC)C=C5[C@]4([H])C3)NCC2)C=C1OC. Density: 1.21±0.1 g/cm³ (20 ºC 760 Torr). Product ID: ACM483170. Alfa Chemistry ISO 9001:2015 Certified. | |
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