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| Product | Description | |
|---|---|---|
| CGP 52411 | CGP 52411. Group: Biochemicals. Grades: Purified. CAS No. 145915-58-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| CGP 52411 | CGP 52411, also called DAPH, inhibits and reverses the formation of Aβ42 fibers (β-sheet content of aggregated β-amyloid (1-42): IC50 = 4.5 μM) in neurons associated with Alzheimer's disease. And it is also a selective inhibitor of the epidermal growth factor receptor (EGFR) (IC50 = 0.3 μM in vitro). Uses: Anti-alzheimer agents; amyloid-β inhibitor. Synonyms: CGP 52411; CGP52411; CGP-52411; 5,6-dianilinoisoindole-1,3-dione; 406-050-3; Z13D008FZ2; 4,5-dianilinophthalimide; DAPH; Cgp 52411; 5,6-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione; 145915-58-8; Cgp-52411; UNII-Z13D008FZ2; CHEMBL268868; 5,6-dianilino-1h-isoindole-1,3(2h)-dione; CHEBI:53110; Z13D008FZ2; AC1Q6JME; DAPH-1; SCHEMBL11017; 4,5-Bis(anilino)phthalimide; D3943_SIGMA; 4,5-bis-(anilino)phthal. CAS No. 145915-58-8. Molecular formula: C20H15N3O2. Mole weight: 329.35. |  |
| CGP52432 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| CGP52432 | CGP52432 is a GABA B receptor antagonist, with an IC 50 of 85 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 139667-74-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103531. |  |
| CGP 52432 | CGP52432 is a potent and selective GABAB receptor antagonist with IC50 value of 85 nM. Synonyms: Cgp 52432; Cgp52432; Cgp52432; 3-[[(3,4-Dichlorophenyl)methyl]amino]propyl] diethoxymethyl)phosphinic acid. Grade: >98 %. CAS No. 139667-74-6. Molecular formula: C15H24Cl2NO4P. Mole weight: 384.24. | |
| CGP 52608 | ?98%, solid. Group: Fluorescence/luminescence spectroscopy. | |
| CGP-53153 | CGP-53153 is a steroidal inhibitor of 5 alpha reductase is a steroidal which effects the conversion of testosterone (T) to 5α-dihydrotestosterone (DHT). In vitro, CGP 53153 competitively inhibited rat microsomal 5α-reductase from prostate by 50% (ICs0) at a concentration of 36 nM compared to the reference compound finasteride which inhibited 5α-reductase with an ICs0 of 11 nM in the same system. In vivo, inhibition of 5α-reductase activity was characterized in three different test systems. Synonyms: (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-(2-cyanopropan-2-yl)-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide; wt1-ricin a; SCHEMBL8823373; CGP 53153; CGP-53153; CGP53153. CAS No. 149281-19-6. Molecular formula: C23H33N3O2. Mole weight: 383.53. | |
| CGP 53353 | CGP 53353, also called DAPH 2, highly selectively inhibits procarcinogenic protein kinase C-βII (PKCβII) ,and it is also an inhibitor of prionogenic Sup35 fibrillization (IC50 ~ 3.4 μM). It inhibits de novo Aβ42 assembly in vitro. Uses: Anti-alzheimer agents; amyloid-β inhibitor. Synonyms: CGP53353; CGP 53353; CGP-53353. 5,6-bis(4-fluoroanilino)isoindole-1,3-dione; DAPH 2; CGP-53353; 145915-60-2; DAPH-7; PKCbetaII/EGFR Inhibitor; CHEMBL7939; 5,6-Bis[(4-fluorophenyl)amino]-2H-isoindole-1,3-dione; 5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE; IN1137; 4,5-bis(4-Fluoroanilino)-phthalimide; CGP 53 353; CG53353; 4,5-Bis(4-fluoroanilino)phthalimide; 4,5-Bis[4-fluoroanilino]phthalimide; PKCbII/EGFR Inhibitor; AC1O8KXF; DAPH-2; MolMap_000016; C7866_SIGMA; SCHEMBL230492; GTPL5163; CTK8E9235; RONQPWQYDRPRGG-UHFFFAOYSA-N; HMS3229K07; HMS3269E05; ZINC600430; CGP53353; BDBM50040930; CGP 53353; DNC003638; MFCD00938569; AKOS015911570; CCG-206784; NCGC00159569-01; NCGC00159569-02; AK394840; HE005407; HE312152; ZB014534; DB-042814; FT-0643387; 5,6-bis(4-fluoroanilino)isoindole-1,3-dione; 5,6-Bis((4-fluorophenyl)amino)isoindoline-1,3-dione; 5,6-Bis-(4-fluoro-phenylamino)-isoindole-1,3-dione; BRD-K32292990-001-01-0; I14-37922; 5,6-bis[(4-fluorophenyl)amino]-2,3-dihydro-1H-isoindole-1,3-dione; CGP 53353|5,6-bis[(4-Fluorophenyl)amino]-1H-isoindole-1,3(2H)-dione. CAS No. 145915-60-2. Molecular formula: C20H13F2N3O2 | |
| CGP 53353 | CGP 53353. Group: Biochemicals. Grades: Purified. CAS No. 145915-60-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CGP-53353 | solid. Group: Fluorescence/luminescence spectroscopy. | |
| CGP 53820 | CGP 53820 has been found to be a HIV-1 Protease pseudosymmetric inhibitor that could probably be effective in the treatment of HIV infections. Synonyms: cgp 53820; 149267-24-3; Cgp-53820; ACETYL-NH-VAL-CYCLOHEXYL-CH2[NCH2CHOH]CH2-BENZYL-VAL-NH-ACETYL; (2S)-2-acetamido-N-[(2S,3S)-4-[[[(2S)-2-acetamido-3-methylbutanoyl]amino]-(cyclohexylmethyl)amino]-3-hydroxy-1-phenylbutan-2-yl]-3-methylbutanamide; C20; 1hih; (S)-2-acetamido-N-((2S,3S)-4-(2-((S)-2-acetamido-3-methylbutanoyl)-1-(cyclohexylmethyl)hydrazinyl)-3-hydroxy-1-phenylbutan-2-yl)-3-methylbuta. Grade: 98%. CAS No. 149267-24-3. Molecular formula: C31H51N5O5. Mole weight: 573.77. | |
| CGP 54626 hydrochloride | The hydrochloride salt form of CGP 54626, a dichloropheny derivative, has been found to be a GABAB receptor antagonist that could probably be effective as an analgesic agent. IC50: 4 nM. Synonyms: CGP 54626 hydrochloride; CGP54626 hydrochloride; CGP-54626 hydrochloride; CGP 54626 HYDROCHLORIDE; [S-(R*,R*)]-[3-[[1-(3,4-DICHLOROPHENYL)ETHYL]AMINO]-2-HYDROXYPROPYL](CYCLOHEXYLMETHYL) PHOSPHINIC ACID HYDROCHLORIDE; (S-(R*,R*))-(3-((1-(3,4-Dichlorophenyl)ethyl)amino)-2-hydroxypropyl)-([3.4-3H]-cyclohexylmethyl)phosphinicacid; [3. Grade: 98%. CAS No. 149184-21-4. Molecular formula: C18H28Cl2NO3P.HCl. Mole weight: 410.31. | |
| CGP 54626 hydrochloride | CGP 54626 (hydrochloride) is a selective antagonist of GABA B receptor with an IC 50 value of 4 nM. CGP 54626 (hydrochloride) can be used to investigate the role of GABA B receptors in neurological signaling [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 149184-21-4. Pack Sizes: 1 mg. Product ID: HY-101378. | |
| CGP 55802A | CGP 55802A has been found to be a photoaffinity ligand that could be used to label NMDA receptor and have high selectivity to glutamate recognition site. Synonyms: Cgp-55802A; Cgp 55802A; (E)-2-Amino-10-((4-azido-2-hydroxy-3-iodobenzoyl)amino)-4-(phosphonomethyl)-3-decenoic acid monosodium salt; 152564-63-1; 2-Amino-10-((4-azido-2-hydroxy-3-iodobenzoyl)amino)-4-phosphonomethyl-dec-3-enoic acid sodium salt; 3-Decenoi. Grade: 98%. CAS No. 152564-63-1. Molecular formula: C18H24IN5NaO7P. Mole weight: 603.29. | |
| CGP 55845 hydrochloride | CGP 55845 hydrochloride is a potent and selective GABAB receptor antagonist (IC50 = 5 nM), which prevents agonist binding (pKi = 8.35) and inhibits release of GABA and glutamate (pEC50 = 8.08 and 7.85, respectively). Synonyms: CGP 55845 HCl; CGP 55845HCl; CGP 55845; CGP55845; CGP-55845; (2S)-3-[[(1S)-1-(3,4-Dichlorophenyl)ethyl]amino-2-hydroxypropyl](phenylmethyl)phosphinic acid hydrochloride. Grade: ≥98% by HPLC. CAS No. 149184-22-5. Molecular formula: C18H22Cl2NO3P.HCl. Mole weight: 438.71. | |
| CGP 55845 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CGP55845 hydrochloride | CGP55845 hydrochloride is a potent and selective GABAB receptor antagonist with an IC 50 of 6 nM. CGP55845 hydrochloride can be used for neurological research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 149184-22-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-103516. | |
| CGP 57380 | CGP 57380. Group: Biochemicals. Grades: Purified. CAS No. 522629-08-9. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGP 57380 | CGP 57380 is a cell-permeable pyrazolo-pyrimidine compound that acts as a selective inhibitor of Mnk1 with IC 50 of 2.2 μM, but has no inhibitory activity against p38, JNK1, ERK1/2, PKC, or Src-like kinases. Uses: Scientific research. Group: Signaling pathways. CAS No. 522629-08-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10520. | |
| CGP 57380 | CGP 57380 is a potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases. Synonyms: CGP-57380; CGP57380; CGP 57380. Grade: >98%. CAS No. 522629-08-9. Molecular formula: C11H9FN6. Mole weight: 244.23. | |
| CGP 57380 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CGP 57813 | CGP 57813 has been found to be a HIV-1 protease inhibitor that has been once developed by Novartis. Synonyms: Cgp 57813; Cgp-57813; Cgp57813; Carbamic acid, (2-hydroxy-4-((4-methoxyphenyl)methyl)-5-((2-methyl-1-(((2-(4-morpholinyl)-2-oxo-1-(phenylmethyl)ethyl)amino)carbonyl)propyl)amino)-5-oxo-1-(phenylmethyl)pentyl)-, 1,1-dimethylethyl ester, (1S-(1R*,2R*,4S*,5(. Grade: 98%. CAS No. 150608-41-6. Molecular formula: C43H58N4O8. Mole weight: 758.94. | |
| CGP-59326 | CGP-59326, a pyrrolopyrimidine derivative, has been found to be an EGFR antagonist and could used in antineoplastic studies. Synonyms: CGP-59326; CGP 59326; CGP59326; CHEMBL306081; 1H-Pyrrolo(2,3-d)pyrimidin-4-amine, N-(3-chlorophenyl)-5,6-dimethyl-; 7H-Pyrrolo(2,3-d)pyrimidin-4-amine, N-(3-chlorophenyl)-5,6-dimethyl-. Grade: 98%. CAS No. 173458-56-5. Molecular formula: C14H13ClN4. Mole weight: 272.73. | |
| CGP60474 | CGP60474 is a promising inhibitor of PKC with a high degree of selectivity versus other serine/threonine and tyrosine kinases and show competitive kinetics relative to ATP. Synonyms: CGP-60474; CGP 60474. Grade: >98%. CAS No. 164658-13-3. Molecular formula: C18H18ClN5O. Mole weight: 355.82. | |
| CGP-62198A | CGP-62198A, a piperidine derivative, could probably be useful in some biological studies. Synonyms: CGP-62198A; CGP 62198A; CGP62198A; UNII-WXF63HI1WD; WXF63HI1WD; SCHEMBL6042796. Benzamide, N-((2S,4S,5S,7S)-7-(((2-(4-acetyl-1-piperidinyl)ethyl)amino)carbonyl)-4-amino-5-hydroxy-8-methyl-2-(1-methylethyl)nonyl)-2-(4-methoxybutoxy)-. Grade: 98%. CAS No. 180183-51-1. Molecular formula: C35H60N4O6. Mole weight: 632.89. | |
| Cgp 6809 | Cgp 6809 is a new methylnitrosoureido-sugar derivative. It is active against a broad spectrum of transplantable tumours in mice and rats. But Phase I clinical trials for the treatment of solid tumor were discontinued. Uses: Cancer. Synonyms: Cgp 6809; Cgp6809; Cgp-6809; ethyl-6-deoxy-3,5-di-O-methyl-6-(3-methyl-3-nitrosoureido)glucofuranoside. Grade: 98%. CAS No. 84069-38-5. Molecular formula: C12H23N3O7. Mole weight: 321.33. | |
| CGP 71683 hydrochloride | CGP 71683 hydrochloride is a highly selective non-peptide antagonist of the NPY Y(5) receptor (IC50= 1.4 nM) with > 1000-fold selectivity over Y1 (IC50= 2765 nM), Y2 (IC50= 7187 nM) and Y4 (IC50= 5637 nM) receptors. Potently inhibits NPY-induced food intake following i.p. administration in diabetic, free-feeding and fasted rats. Synonyms: N-[[4-[[(4-aminoquinazolin-2-yl)amino]methyl]cyclohexyl]methyl]naphthalene-1-sulfonamide; hydrochloride; CGP 71683 A; CGP-71683A; CGP 71683 hydrochloride; CGP71683 hydrochloride; CGP-71683 hydrochloride. Grade: >99 %. CAS No. 192322-50-2. Molecular formula: C26H29N5O2S.HCl. Mole weight: 512.07. | |
| CGP 71683 hydrochloride | CGP 71683 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 192322-50-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGP71683 hydrochloride | CGP71683 hydrochloride is a competitive neuropeptide Y5 receptor antagonist with a K i of 1.3 nM, and shows no obvious activity at Y1 receptor ( K i , >4000 nM) and Y2 receptor ( K i , 200 nM) in cell membranes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGP71683A. CAS No. 192322-50-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-107723. | |
| CGP74514A | CGP74514A is a cell permeable Cdk inhibitor selective for Cyclin-dependent kinase-1 (Cdk1) (IC50=25nM). CGP74514A was also reported also to affect the activities of other kinases including PKCα (IC50=6.1μM), PKA (IC50=125μM) and EGFR (IC50>10μM), but only at much higher concentrations. Synonyms: 2-N-[(1R,2S)-2-aminocyclohexyl]-6-N-(3-chlorophenyl)-9-ethylpurine-2,6-diamine; CGP 74514A; 481724-82-7 (CGP74514A HCl salt); CGP-74514A; CGP74514A; N(2)-(2-aminocyclohexyl)-N(6)-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine. Grade: >98%. CAS No. 190653-73-7. Molecular formula: C19H24ClN7. Mole weight: 385.9. | |
| CGP 74514 dihydrochloride | CGP 74514 Dihydrochloride is a potent cdk1 inhibitor with IC50 of 25 nM. It can reduce Akt phosphorylation and increase mitochondrial damage in leukemia cells. Synonyms: CGP 74514. Grade: ≥98%. Molecular formula: C19H24ClN7·2HCl. Mole weight: 458.82. | |
| CGP-75254A | CGP-75254A, a novel oral iron chelator, across Caco-2 cells in an attempt to model intestinal epithelial cell permeability in man. Studies predicted that absorption of CGP-75254A is likely to be virtually complete at pH values between 5.5 and 7.0. However, at pH 8.0 permeability is predicted as negligible. Synonyms: sodium; 2-[2-[(2-ethoxy-2-oxoethyl)-[(2-hydroxyphenyl)methyl]amino]ethyl-[(2-hydroxyphenyl)methyl]amino]acetate; CGP-75254A; CGP 75254A; CGP75254A; UNII-94KC20I6YX; 199485-27-3 (CGP-75254A Free Acid). Grade: >98%. CAS No. 199485-26-2. Molecular formula: C22H27N2NaO6. Mole weight: 438.45. | |
| CGP-75355 | CGP-75355 is an HIV Protease inhibitor (EC50= 0.7 nM). Uses: Hiv protease inhibitors. Synonyms: CGP-75355; CGP 75355; CGP75355; UNII-4ZE7DBE752; methyl N-[(2S)-1-[2-[(2S,3S)-2-hydroxy-3-[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-4-phenylbutyl]-2-[(4-phenylphenyl)methyl]hydrazinyl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate; 232632, BMS; 3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-((4-(2-pyridinyl)phenyl)methyl)-2,5,6,10,13-pentaazatetradecanedioic acid dimethyl ester; atazanavir; atazanavir sulfate; BMS 232632; BMS 232632 05; BMS-232632; BMS-232632-05; BMS232632; BMS23263205. Grade: >98%. CAS No. 191594-64-6. Molecular formula: C39H53N5O7. Mole weight: 703.87. | |
| CGP 76030 | CGP76030 is a ual-specific Src and Abl kinase inhibitor, inhibit growth and survival of cells expressing imatinib mesylate-resistant Bcr-Abl kinases. Uses: Ual-specific src and abl kinase inhibitor. Synonyms: CGP-76030; CGP76030; CGP76030; CGP-076030. 7-(4-(2-((2-methoxyethyl)amino)ethoxy)phenyl)-5-(3-methoxyphenyl)-7H-Pyrrolo(2,3-d)pyrimidin-4-amine. Grade: ≥98%. CAS No. 497152-38-2. Molecular formula: C24H27N5O3. Mole weight: 433.5. | |
| CGP77675 | CGP77675 is an orally active and potent inhibitor of Src family kinases. CGP77675 inhibits phosphorylation of peptide substrates and autophosphorylation of purified Src ( IC 50 s of 5-20 and 40 nM, respectively), and also inhibits Src, EGFR, KDR, v-Abl, and Lck with IC 50 s of 5-20, 40, 20, 150, 1000, 310, and 290 nM, respectively. Anticancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 234772-64-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W062835. | |
| CGP77675 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CGP 77675 | CGP 77675 is a potent Src kinase inhibitor. It can be used to maintain mouse embryonic stem cell (mESC) in combination with CHIR99021. Uses: Protein kinase inhibitors. Synonyms: CGP-77675; 1-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)phenethyl)piperidin-4-ol. Grade: >98%. CAS No. 234772-64-6. Molecular formula: C26H29N5O2. Mole weight: 443.55. | |
| CGP 78608 | CGP 78608 is a potent and selective NMDA receptor antagonist that exhibits an anticonvulsant effect in vivo following systemic administration. Synonyms: Phosphonic acid, P-[(1S)-1-[[(7-bromo-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl]amino]ethyl]-; P-[(1S)-1-[[(7-Bromo-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl]amino]ethyl]phosphonic acid; Phosphonic acid, [(1S)-1-[[(7-bromo-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl]amino]ethyl]-; Phosphonic acid, [1-[[(7-bromo-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl]amino]ethyl]-, (S)-; CGP78608; CGP-78608; [(1S)-1-{[(7-bromo-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)methyl]amino}ethyl]phosphonic acid; (S)-(1-(((7-Bromo-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)methyl)amino)ethyl)phosphonic acid. Grade: ≥95%. CAS No. 206648-13-7. Molecular formula: C11H13BrN3O5P. Mole weight: 378.12. | |
| CGP 78608 hydrochloride | CGP 78608 hydrochloride is a potent and selective NMDA antagonist with > 500-fold selectivity over kainate and AMPA receptors (IC50 = 2.7 and 3 μM, respectively). CGP 78608 exhibits an anticonvulsant effect in vivo following systemic administration. Synonyms: CGP78608 hydrochloride; CGP-78608 hydrochloride; [(1S)-1-[[(7-Bromo-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl]amino]ethyl]phosphonic acid hydrochloride; Phosphonic acid, P-[(1S)-1-[[(7-bromo-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl]amino]ethyl]-, hydrochloride (1:1); (S)-(1-(((7-Bromo-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)methyl)amino)ethyl)phosphonic acid hydrochloride. Grade: ≥98% by HPLC. CAS No. 1135278-54-4. Molecular formula: C11H13BrN3O5P.HCl. Mole weight: 414.58. | |
| CGP 78608 hydrochloride | CGP 78608 hydrochloride is a highly potent and selective antagonist at the glycine-binding site of the NMDA receptor , with an IC 50 of 6 nM. CGP 78608 hydrochloride acts as a potentiator of GluN1/GluN3A-mediated glycine currents, with an estimated EC 50 in the low nM range (26.3 nM). Anticonvulsant activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1135278-54-4. Pack Sizes: 1 mg. Product ID: HY-107701. | |
| CGP7930 | CGP7930 (3-(3,5-Di-tert-butyl-4-hydroxy) phenyl-2, 2-dimethylpropanol) is a positive metabotropic GABAB receptor allosteric modulator. CGP7930 enhances the inhibitory effect of l-baclofen on the oscillatory activity of cultured cortical neurons [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 57717-80-3. Pack Sizes: 1 mg. Product ID: HY-103502. | |
| CGP7930 | CGP7930 is a positive allosteric modulator at the GABAB receptor. It has anxiolytic effects in animal studies, and has a synergistic effect with GABAB agonists such as baclofen and GHB. It increases the potency and efficacy of GABA at both native and recombinant GABAB receptors with EC50 values of 5.37 and 4.60μM respectively. It also enhances the inhibitory effect of the agonist L-baclofen in cultured cortical neurons. It reduces operant self-administration of ethanol and cocaine in rats. Uses: Cgp7930 has anxiolytic effects in animal studies, and has a synergistic effect with gabab agonists such as baclofen and ghb. it reduces operant self-administration of ethanol and cocaine in rats. Synonyms: 3,5-Bis(1,1-dimethylethyl)-4-hydroxy-beta,beta-dimethylbenzenepropanol; 2,6-Ditert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol; 3-(3',5'-Di-tert-butyl-4'-hydroxy)phenyl-2,2-dimethylpropanol; CGP7930; CGP-7930; CGP 7930. Grade: >98 %. CAS No. 57717-80-3. Molecular formula: C19H32O2. Mole weight: 292.46. | |
| CGP 7930 | CGP 7930. Group: Biochemicals. Grades: Purified. CAS No. 57717-80-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGP 7930 (GABA B Receptor Antagonist, CGP7930, CGP 7930, CGP-7930) | A blood brain barrier permeable, positive allosteric modulator of the metabotropic GABAB receptor. Shown to modulate GABAB receptor in the high affinity state and thereby increases agonist affinity for the receptor. Also enhances agonist potency and efficacy even on recombinant GABAB receptors. Exhibits anxiolytic effects in rodents. Group: Biochemicals. Grades: Highly Purified. CAS No. 57717-80-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CGP-79807 | CGP-79807 is a potent CDC2 protein kinase inhibitor that originated by Novartis. In Sep 2000, Preclinical development for Cancer in Switzerland was on-going, but no development has been reported. Uses: Cancer. Synonyms: CGP-79807; CGP 79807; CGP79807; UNII-532R2SRL4B; CHEMBL172140; 532R2SRL4B; SCHEMBL5842014; SCHEMBL5842019; BDBM50073763. 3-((9-ethyl-2-((trans-4-hydroxycyclohexyl)amino)-9H-purin-6-yl)amino)-Benzonitrile. Grade: 98%. CAS No. 1229665-91-1. Molecular formula: C20H23N7O. Mole weight: 370.44. | |
| Cgp 8716 | Cgp 8716 is a major metabolite of GP53,633 which is a basic non-steroidal anti-inflammatory agent Originated by Novartis. Synonyms: Cgp 8716; Cgp8716; Cgp-8716. 4-(2-(1,1-dimethylethyl)-5-(3-pyridinyl)-1H-imidazol-4-yl)-Phenol. Grade: 98%. CAS No. 84782-21-8. Molecular formula: C18H19N3O. Mole weight: 293.36. | |
| CGP-9000 | CGP-9000 is a semisynthetic cephalosporin which has a wide antibacterial spectrum. Its antibacterial activity was similar to that of cefalexin in vitro, but the effect of oral administration was 2-7 times stronger than that of cefalexin and cefradine in mice. Synonyms: CGP 9000; BRN 0587499. Molecular formula: C16H19N3O5S. Mole weight: 365.40. | |
| Cg-Prp | Cg-Prp is the resulting 37-amino acid peptide composed of an acidic region and a cationic proline-rich region. | |
| CGRP (83-119), rat TFA | Calcitonin Gene Related Peptide (CGRP) (83-119), rat acts through calcitonin receptor-like receptor. Synonyms: Calcitonin Gene Related Peptide(83-119), rat TFA. Molecular formula: C162H262N50O52S2.C2HF3O2. Mole weight: 3920.32. | |
| CGRP 8-37 (human) | CGRP 8-37 (human) is a peptide antagonist for CGRP1 receptors. Uses: Miotics. Synonyms: FBHuman; HCGRP-(8-37); HY-P1014; HY P1014; HYP1014; CGRP 8 37. Grade: >95%. CAS No. 119911-68-1. Molecular formula: C139H230N44O38. Mole weight: 3125.6. | |
| CGRP 8-37 (human) | CGRP 8-37 (human). Group: Biochemicals. Grades: Purified. CAS No. 119911-68-1. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| CGRP 8-37 (rat) | CGRP 8-37 (rat). Group: Biochemicals. Grades: Purified. CAS No. 129121-73-9. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| CGRP antagonist 1 | CGRP antagonist 1 is a highly potent antagonist of CGRP receptor (Ki = 35 nM; IC50 = 57 nM). Synonyms: (S)-N-(2''-oxo-1,1'',2'',3-tetrahydrospiro[indene-2,3''-pyrrolo[2,3-b]pyridine]-5-yl)-2-(2-oxo-2'',3'',5'',6''-tetrahydrospiro[indoline-3,4''-pyran]-1-yl)acetamide; Spiro[3H-indole-3,4'-[4H]pyran]-1(2H)-acetamide, 2',3',5',6'-tetrahydro-2-oxo-N-[(2S)-1,1',2',3-tetrahydro-2'-oxospiro[2H-indene-2,3'-[3H]pyrrolo[2,3-b]pyridin]-5-yl]-; N-[(2S)-2'-Oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridin]-5-yl]-2-(2-oxo-2',3',5',6'-tetrahydrospiro[indole-3,4'-pyran]-1(2H)-yl)acetamide. Grade: ≥95%. CAS No. 1123757-49-2. Molecular formula: C29H26N4O4. Mole weight: 494.54. | |
| CGRP (rat) | α-CGRP (rat) is an endogenous neuropeptide displaying vasodilator, cardiovascular, pro-inflammatory and metabolic effects. Synonyms: Calcitonin Gene-Related Peptide (rat). Grade: >95%. CAS No. 83651-90-5. Molecular formula: C162H262N50O52S2. Mole weight: 3806.3. | |
| CGRP (rat) | CGRP (rat). Group: Biochemicals. Grades: Purified. CAS No. 83651-90-5. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
| CGS 12066B dimaleate | CGS 12066B dimaleate. Group: Biochemicals. Grades: Purified. CAS No. 109028-10-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGS 12066B dimaleate | CGS 12066B dimaleate is a 5-HT1B full agonist, which is 10-fold selective over 5-HT1A and 1000-fold selective over 5-HT2C receptors. Uses: Serotonin receptor agonists. Synonyms: CGS 12066B dimaleate; CGS12066B dimaleate; CGS-12066B dimaleate; 7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo[1,2-a]-quinoxaline dimaleate. Grade: ≥98% by HPLC. CAS No. 109028-10-6. Molecular formula: C17H17F3N4.2C4H4O4. Mole weight: 566.49. | |
| Cgs 15696 | Cgs 15696 is an adenosine antagonist. Synonyms: 9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5(6H)-one; 9-chloro-2-(furan-2-yl)-5H,6H-[1,2,4]triazolo[1,5-c]quinazolin-5-one. Grade: 98% by HPLC. CAS No. 104615-00-1. Molecular formula: C13H7ClN4O2. Mole weight: 286.67. | |
| CGS 15943 | CGS 15943. Group: Biochemicals. Grades: Purified. CAS No. 104615-18-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGS 15943 | CGS 15943 is a potent and orally bioactive adenosine receptor antagonist (Ki = 3.5, 4.2, 16 and 51 nM for human A1, A2A, A2B and A3 receptors, respectively). Synonyms: CGS 15943; CGS15943; CGS-15943; 9-Chloro-2-(2-furanyl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine. Grade: ≥99% by HPLC. CAS No. 104615-18-1. Molecular formula: C13H8ClN5O. Mole weight: 285.69. | |
| CGS 15943 | CGS 15943 is an orally bioavailable non-xanthine Adenosine Receptor antagonist. Its Ki for human A1, A2A, A2B, and A3 Adenosine Receptors are 3.5, 4.2, 16, and 50 nM in transfected CHO cells, respectively. [1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 104615-18-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100678. | |
| CGS-15943 | solid. Group: Fluorescence/luminescence spectroscopy. | |
| CGS 19755 | CGS 19755 is a potent and competitive NMDA receptor antagonist with anticonvulsant, anxiolytic, analgesic and neuroprotective activity. Synonyms: CGS-19755; CGS 19755; CGS19755; CPDD 0027; CPDD-0027; CPDD0027; Selfotel; cis-4-[Phosphomethyl]-piperidine-2-carboxylic acid. CAS No. 110347-85-8. Molecular formula: C7H14NO5P. Mole weight: 223.17. | |
| CGS 19755 | CGS 19755. Group: Biochemicals. Grades: Purified. CAS No. 110347-85-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGS20625 | CGS-20625 is an anxiolytic drug used in scientific research. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic. It produces anxiolytic and anticonvulsant effects, but with no sedative effects even at high doses, and no significant muscle relaxant effects. It is orally active in humans, but with relatively low bioavailability. CGS-20625 is a positive allosteric modulator at several GABAA receptors types. Due to its alicyclic moiety potency at γ1 subunit, containing receptor types is more pronounced for CGS-20625 compared to benzodiazepines. γ1 subunits are expressed at higher levels in the central amygdala. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CGS20625; CGS-20625; CGS 20625. Product Category: Others. Appearance: Solid powder. CAS No. 111205-55-1. Molecular formula: C18H19N3O2. Mole weight: 309.37. Purity: >98%. IUPACName: Cyclohepta(b)pyrazolo(3,4-d)pyridin-3(2H)-one, 5,6,7,8,9,10-hexahydro-2-(4-methoxyphenyl)-. Canonical SMILES: O=C1N(C2=CC=C(OC)C=C2)N=C3C(CCCCC4)=C4NC=C31. Product ID: ACM111205551-1. Alfa Chemistry ISO 9001:2015 Certified. |  |
| CGS 20625 | CGS 20625 is a partial agonist for the benzodiazepine binding site of the GABAA receptor used as an anti-anxiety drug. It acts as a central benzodiazepine receptor agonist (IC50 = 1.3 nM) with no affinity for other neurotransmitter receptor binding sites. Uses: Anti-anxiety drug. Synonyms: CGS 20625; CGS20625; CGS-20625; 5,6,7,8,9,10-Hexahydro-2-(4-methoxyphenyl)cyclohepta[b]pyrazolo[3,4-d]pyridin-3(2H)-one. Grade: ≥99% by HPLC. CAS No. 111205-55-1. Molecular formula: C18H19N3O2. Mole weight: 309.36. | |
| CGS 20625 | CGS 20625. Group: Biochemicals. Grades: Purified. CAS No. 111205-55-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CGS 21680 | CGS 21680, an A2 adenosine receptor selective agonist, has been found to be probably effective in inducing vasorelaxation and increasing in heart rate. Uses: Cgs 21680 is an a2 adenosine receptor selective agonist that has been found to be probably effective in inducing vasorelaxation and increasing in heart rate. Synonyms: Cgs 21680; CGS-21680; CGS21680; 2-(4-(2-Carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine; UNII-T5HB1E831H; CHEMBL331372. Grade: 95%. CAS No. 120225-54-9. Molecular formula: C23H29N7O6. Mole weight: 499.52. | |
| CGS 21680A | CGS 21680A. Group: Biochemicals. Alternative Names: CGS 21680 hydrochloride; 4- [2- [ [6-Amino-9- (N-ethyl-b-D-ribofuranuronamidosyl) -9H-purin-2-yl] amino] ethyl] benzenepropanoic acid hydrochloride. Grades: Highly Purified. CAS No. 124431-80-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C23H30ClN7O6. US Biological Life Sciences. | Worldwide |
| CGS 21680C Sodium Salt | A selective A2A receptor agonist. Uses: A selective a2a receptor agonist. Synonyms: 4-[2-[[6-Amino-9-(N-ethyl-β-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic Acid Monosodium Salt. Grade: 95%. CAS No. 120225-64-1. Molecular formula: C23H28N7NaO6. Mole weight: 521.5. | |
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