A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Cytovaricin is an antibiotic produced by Streptomyces sp. H-230 and Str. collinus H-230. It has the activity of inhibiting Yoshida sarcoma cells and has weak anti-phytopathogenic fungi and chlorella activity. CAS No. 79553-45-0. Molecular formula: C47H80O16. Mole weight: 901.13.
Cytovaricin B
Cytovaricin B is a Janus kinase-signal transducer and activation protein (JAK-STAT) inhibitor produced by Streptamyces torulosus 3197-GM1. CAS No. 129985-88-2. Molecular formula: C48H82O16. Mole weight: 915.15.
Cytoxazone
Cytoxazone is a cytokine regulator produced by Streptornyces sp. RK95-31. It inhibits the production of IL-4 and IL-10 induced by Pokeween mitogen (PWM) at 6.25-25 μg/mL, but does not inhibit the production of GM-CSF induced by PWM. Synonyms: (-)-Cytoxazone. Grades: >98%. CAS No. 42902-32-9. Molecular formula: C11H13NO4. Mole weight: 223.22.
Cy-Tripglu
Tripod Detergents. Alternative Names: N-(1,3-bis(Glucopyranoside)propan-2-yl)-3-butyl-3-cyclohexylheptanamide. CAS No. 1126527-71-6. Molecular formula: C32H59NO13. Mole weight: 665.8. Purity: ≥97%.
Cy-vBRIDP
Ligand used in the Pd-catalyzed amination of aryl halides. Ligand used for Suzuki-Miyaura coupling. Group: Heterocyclic organic compound. Alternative Names: AKOS025295265; Acm³84842244; CTK8E6999; 1,1-Diphenyl-2-(dicyclohexylphosphino)propene; 1-Methyl-2,2-diphenylvinyldicyclohexylphosphine; Cy-vBRIDP; 2-(Dicyclohexylphosphino)-1,1-diphenyl-1-propene, Dicyclohexyl(1-methyl-2,2-diphenylvinyl)phosphine; Cy-vBRIDP(regR); DTXSID40475778; DICYCLOHEXYL(1-METHYL-2,2-DIPHENYLVINYL)PHOSPHINE. CAS No. 384842-24-4. Molecular formula: C27H35P. Mole weight: 390.551g/mol. IUPACName: dicyclohexyl(1,1-diphenylprop-1-en-2-yl)phosphane. Canonical SMILES: CC (=C (C1=CC=CC=C1)C2=CC=CC=C2)P (C3CCCCC3)C4CCCCC4. Catalog: ACM384842244.
CZ415
CZ415 is a highly selective potent mTOR inhibitor with little activity on other lipid and protein kinases with efficacy in a collagen induced arthritis model and exhibits excellent cell permeability. In the issue, Bergamini et al., who has identified CZ415, confirmed with its extraordinary selectivity, drug-like properties and proven efficacy in vivo, CZ415 represents an ideal molecule for the pharmacological investigation of mTOR pathophysiological role in vivo. Assessed in dose response format from HEK293T cells after treatment with CZ415: 1. inhibition of S6RP (downstream of mTORC1) phosphorylation in HEK293T: IC50 = 14.5 nM; 2. inhibition of Akt (mTORC2 substrate) phosphorylation in HEK293T: IC50 = 14.8 nM; 3. inhibition of IFNγ release in stimulated human whole blood: IC50 = 226 nM. Synonyms: CZ415; CZ-415; CZ 415; (S)-1-(4-(7,7-dimethyl-4-(3-methylmorpholino)-6,6-dioxido-5,7-dihydrothieno[3,4-d]pyrimidin-2-yl)phenyl)-3-ethylurea. CAS No. 1429639-50-8. Molecular formula: C22H29N5O4S. Mole weight: 459.57.
CZBDF
Ambipolar Semiconductors. Alternative Names: 3,7-Bis[4-(9H-carbazol-9-yl)phenyl]-2,6-diphenylbenzo[1,2-b:4,5-b']difuran 9,9'-[(2,6-Diphenylbenzo[1,2-b:4,5-b']difuran-3,7-diyl)bis(4,1-phenylene)]bis(9H-carbazole). CAS No. 1092578-51-2. Molecular formula: C58H36N2O2. Mole weight: 792.94. Appearance: White to Orange to Green powder to crystal. Purity: >98.0%(HPLC). IUPACName: 9-[4-[3-(4-carbazol-9-ylphenyl)-2,6-diphenylfuro[2,3-f][1]benzofuran-7-yl]phenyl]carbazole. Canonical SMILES: C1=CC=C (C=C1) C2=C (C3=CC4=C (C=C3O2) C (=C (O4) C5=CC=CC=C5) C6=CC=C (C=C6) N7C8=CC=CC=C8C9=CC=CC=C97) C1=CC=C (C=C1) N1C2=CC=CC=C2C2=CC=CC=C21. Catalog: ACM1092578512-1.
CZC24832 is the first selective inhibitor of phosphoinositide 3-kinase γ (PI3Kγ) with efficacy in in vitro and in vivo models of inflammation. Extensive target- and cell-based profiling of CZC24832 revealed regulation of interleukin-17-producing T helper cell (T(H)17) differentiation by PI3Kγ, thus reinforcing selective inhibition of PI3Kγ as a potential treatment for inflammatory and autoimmune diseases. Synonyms: CZC24832; CZC-24832; CZC 24832. Grades: 0.98. CAS No. 1159824-67-5. Molecular formula: C15H17FN6O2S. Mole weight: 364.399.
Selective inhibitor of PI 3-Kinase gamma (IC50 = 1.0um in a PI 3-Kgamma-dependent fMLP-induced neutrophil migration assay). Exhibits limited off-target effects in kinome profiling of 154 identified lipid and protein kinases and 922 other proteins. Orally effective in a rodent model of inflammatory disease. Group: Biochemicals. Grades: Highly Purified. CAS No. 1159824-67-5. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CZC-25146
CZC-25146 is a compound that acts as an inhibitor of LRRK2, a factor in the expression of Parkinsons. Synonyms: CZC25146; CZC 25146. Grades: >98%. CAS No. 1191911-26-8. Molecular formula: C22H25FN6O4S. Mole weight: 488.54.
CZC-25146 hydrochloride
CZC-25146 is a compound that acts as an inhibitor of LRRK2, a factor in the expression of Parkinsons's disease, and is ATP-competitive. Synonyms: CZC25146 hydrochloride; CZC 25146 hydrochloride. Grades: 0.98. CAS No. 1330003-04-7. Molecular formula: C22H26ClFN6O4S. Mole weight: 524.996.
CZC-54252
Potent inhibitor of leucine-rich repeat kinase 2 (LRRK2) (IC50 values are 1.28 nM and 1.85 nM for wild-type and G2019S mutant forms of LRRK2 respectively). Attenuates neuronal injury induced by LRRK2-G2019S mutant activity in primary human neurons (EC50 = 1 nM). Synonyms: CZC-54252; CZC 54252; CZC54252. Grades: >98%. CAS No. 1191911-27-9. Molecular formula: C22H25ClN6O4S. Mole weight: 504.99.
CZC-54252 HCl
CZC-54252 is a potent inhibitor of leucine-rich repeat kinase 2 (LRRK2) with IC50 values 1.28 nM and 1.85 nM for wild-type and G2019S mutant forms of LRRK2 respectively. CZC-54252 attenuates neuronal injury induced by LRRK2-G2019S mutant activity in primary human neurons (EC50 = 1 nM). Activating mutations in leucine-rich repeat kinase 2 (LRRK2) are present in a subset of Parkinson's disease (PD) patients and may represent an attractive therapeutic target. Group: Inhibitors. Alternative Names: CZC-54252 HCl; CZC-54252 hydrochloride; CZC-54252; CZC 54252; CZC54252. CAS No. 1784253-05-9. Molecular formula: C22H26Cl2N6O4S. Mole weight: 541.45. Appearance: Solid powder. Purity: >98%. IUPACName: N-(2-((5-chloro-2-((2-methoxy-4-morpholinophenyl)amino)pyrimidin-4-yl)amino)phenyl)methanesulfonamide hydrochloride. Canonical SMILES: CS (=O) (NC1=CC=CC=C1NC2=NC (NC3=CC=C (N4CCOCC4)C=C3OC)=NC=C2Cl)=O. [H]Cl. Catalog: ACM1784253059.
CZC 54252 hydrochloride
CZC 54252 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1191911-27-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CZC-8004
CZC-8004 is an aminopyrimidine which is a pan-kinase inhibitor that binds a range of tyrosine kinases, including ABL, BTK, FAK, FER, JAK1, SRC, SYK, TEC, TNK1, TYK2, and YES. Synonyms: Dianilinopyrimidine-01; CZC-00008004. Grades: ≥98%. CAS No. 916603-07-1. Molecular formula: C17H16FN5. Mole weight: 309.3.
Cz-Ph-DRZ
Organic Light Emitting Diode (OLED). Alternative Names: 9-(4-(4,6-Diphenylpyrimidin-2-yl)phenyl)-9H-carbazole. CAS No. 1106729-87-6. Molecular formula: C34H23N3. Mole weight: 473.57 g/mol. Catalog: ACM1106729876.