A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Fludarabine phosphate impurity A is an impurity of Fludarabine phosphate, the salient therapeutic recourse for chronic lymphocytic leukemia. Grade: > 95%. Molecular formula: C10H14N5O8P. Mole weight: 363.23.
Fludarabine phosphate impurity B
Fludarabine phosphate impurity B isan impurity of Fludarabine phosphate, a chemotherapy drug primarily used to treat chronic lymphocytic leukemia. Grade: > 95%. CAS No. 149297-79-0. Molecular formula: C5H5N5O. Mole weight: 151.13.
Fludarabine Phosphate Impurity C
Fludarabine Phosphate Impurity C is an impurity of Fludarabine Phosphate with pronounced application in the therapy of diverse malignancies such as chronic lymphocytic leukemia (CLL) and non-Hodgkin's lymphoma (NHL). Grade: > 95%. Molecular formula: C10H14FN5O10P2. Mole weight: 445.20.
Fludarabine Phosphate Impurity D
Fludarabine Phosphate Impurity D is an impurity of Fludarabine Phosphate, a well-established therapeutic agent efficacious in treating B-cell chronic lymphocytic leukemia (CLL). Grade: > 95%. Molecular formula: C5H4FN5. Mole weight: 153.12.
Fludarabine Phosphate Impurity F
Fludarabine Phosphate Impurity F is a byproduct found in the manufacturing process of the chemotherapy drug Fludarabine Phosphate, which is used to treat B-cell chronic lymphocytic leukemia and lymphoma. Its exact role in the biomedical industry is not well understood and further research is needed. Synonyms: [(2R,3S,4S,5R)-5-(6-amino-2-ethoxypurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate. Grade: > 95%. CAS No. 159002-28-5. Molecular formula: C12H18N5O8P. Mole weight: 391.28.
Fludarabine triphosphate
Fludarabine triphosphate is a cytotoxic metabolite of Fludarabine phosphate. It inhibits ribonucleotide reductase and DNA polymerase and ultimately leads to cellular apoptosis. Synonyms: F-ara-ATP. CAS No. 74832-57-8. Molecular formula: C10H15FN5O13P3. Mole weight: 525.17.
Fludarabine triphosphate trisodium
Fludarabine triphosphate (F-ara-ATP) trisodium, the active metabolite of (HY-B0069), is a potent, noncompetitive and specific inhibitor of DNA primase, with an IC50 of 2.3 ?M and a Ki of 6.1 ?M. Fludarabine triphosphate trisodium inhibits DNA synthesis by blocking DNA primase and primer RNA formation. Fludarabine triphosphate trisodium inhibits ribonucleotide reductase and DNA polymerase and ultimately leads to cellular apoptosis[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: F-ara-ATP trisodium. Pack Sizes: 5 mg (100 mM * 84.59 ?L in Water); 10 mg (100 mM * 169.17 ?L in Water); 25 mg (100 mM * 422.93 ?L in Water); 50 mg (100 mM * 845.85 ?L in Water); 100 mg (100 mM * 1.69 mL in Water). Product ID: HY-136650A.
Fludazonium Chloride
Fludazonium chloride is an antifungal agent used to treat and prevent superficial and systemic fungal infections. Synonyms: R23633; NSC351149; 1-[2,4-dichlorobenzyl)oxy]phenethyl]-3-(p-fluorophenacyl)imidazolium chloride; 1H-Imidazolium, 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-3-[2-(4-fluorophenyl)-2-oxoethyl]-, chloride (1:1); 1-[2,4-Dichloro-β-[(2,4-dichlorobenzyl)oxy]phenethyl]-3-(p-fluorophenacyl)imidazolium chloride. Grade: 95%. CAS No. 53597-28-7. Molecular formula: C26H20Cl5FN2O2. Mole weight: 588.71.
Fludeoxyglucose
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Fludeoxyglucose Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Fludeoxyglucose Related Compound B
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Fludioxonil
Fludioxonil is a phenylpyrrole fungicide used to control a range of diseases, including Fusarium, Rhizoctonia, and Alternaria. It also inhibits glucose transport-related phosphorylation and reduces mycelial growth. Synonyms: 1H-Pyrrole-3-carbonitrile, 4-(2,2-difluoro-1,3-benzodioxol-4-yl)-; Beret Gold; Celeste; CGA 173506; Fludioxonil; Geoxe; Maxim; Maxim (pesticide); Maxim 4FS; Maxim PSP; Maxin XL; Saphire; Savior; Scholar; Seibia; Spirato; Spirato 480 FS. Grade: 95%. CAS No. 131341-86-1. Molecular formula: C12H6F2N2O2. Mole weight: 248.19.
Fludioxonil
Fludioxonil (CGA-173506) is a phenylpyrrole-type fungicide with oral activity that can inhibit the growth of S. sclerotiorum. Fludioxonil promotes tumor growth and metastasis, and induces cardiac toxicity. Fludioxonil causes cytoskeletal disruption, DNA damage, and apoptosis in mouse glioma cells [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGA-173506. CAS No. 131341-86-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-W021040.
Fludioxonil
250mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C12H6F2N2O2. CAS No. 131341-86-1. Prepack ID 89981214-250mg. Molecular Weight 248.19. See USA prepack pricing.
Fludrocortisone is a synthetic corticosteroid with moderate glucocorticoid potency and much greater mineralocorticoid potency. It is used for its mineralocorticoid activity and not for its glucocorticoid activity. It has anti-inflammatory activity. Uses: Fludrocortisone could be used against cerebral salt wasting syndrome for behaving the role as a anti-inflammatory agent. Synonyms: (11β)-9-Fluoro-11,17,21-trihydroxypregn-4-ene-3,20-dione; 9α-Fluorohydrocortisone; 9α-Fluoro-17-hydroxycorticosterone; NSC 11318; 9α-Fluorcortisol; 17,21-trihydroxy-20-dion(11beta)-pregn-4-ene-9-fluoro-11; 9-fluoro-11-beta,17,21-trihydroxy-pregn-4-ene-20-dione. Grade: > 95%. CAS No. 127-31-1. Molecular formula: C21H29FO5. Mole weight: 380.46.
Fludrocortisone
Fludrocortisone, a synthetic mineralocorticoid with anti-inflammatory activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 9α-Fludrocortisone; 9α-Fluorcortisol. CAS No. 127-31-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-B1203.
Fludrocortisone
Fludrocortisone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (11β)-. Product Category: Steroidal Compounds. Appearance: White Solid. CAS No. 127-31-1. Molecular formula: C21H29FO5. Mole weight: 380.45. Purity: 0.95. IUPACName: fludrocortisone. Density: 1.3g/cm³. Product ID: ACM127311. Alfa Chemistry ISO 9001:2015 Certified.
Fludrocortisone
Fludrocortisone. Group: Biochemicals. Grades: Highly Purified. CAS No. 127-31-1. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C21H29FO5. US Biological Life Sciences.
Source: Synthetic. Group: Biochemicals. Alternative Names: 9a-Fluoro-17-hydroxycorticosterone, Fluohydrisone, Astonin H. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Fludrocortisone acetate
Fludrocortisone acetate (9α-Fludrocortisone acetate) is an orally active synthetic mineralocorticoid. Fludrocortisone acetate can effectively control sodium retention. Fludrocortisone acetate is used in studies of cardiac injury, adrenal insufficiency and orthostatic hypotension [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 9α-Fludrocortisone acetate; 9α-Fluorcortisol acetate. CAS No. 514-36-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B1203A.
Fludrocortisone Acetate
Fludrocortisone acetate is a synthetic corticosteroid with more mineralocorticoid than glucocorticoid activity. Uses: A mineralocorticoid. Synonyms: 17-dihydroxy-20-dion(11-beta)-pregn-4-ene-21-(acetyloxy)-9-fluoro-11; 20-dione,9-fluoro-11-beta,17,21-trihydroxy-pregn-4-ene-21-acetate; 9-fluoro-11-beta,17,21-trihydroxypregn-4-ene-3,20-dione21-acetate; 9-fluoro-17-hydroxy-corticosteron21-acetate; (11β)-21-(. Grade: > 95%. CAS No. 514-36-3. Molecular formula: C23H31FO6. Mole weight: 422.50.
Fludrocortisone Acetate
A mineralocorticoid. Group: Biochemicals. Alternative Names: (11 β)-21-(Acetyloxy)-9-fluoro-11,17-dihydroxypregn-4-ene-3,20-dione; 9-Fluorohydrocortisone Acetate. Grades: Highly Purified. CAS No. 514-36-3. Pack Sizes: 1g. US Biological Life Sciences.
Fludrocortisone Acetate-[d6] is a deuterium labelled form of Fludrocortisone Acetate, which is a derivative of Fludrocortisone. Fludrocortisone is a corticosteroid used to treat adrenogenital syndrome, postural hypotension, and adrenal insufficiency. Synonyms: Fludrocortisone Acetate-D6; Fludrocortisone-21-Acetate-D6; 21-(Acetyloxy)-9-fluoro-11,17-dihydroxypregn-4-ene-3,20-dione-D6; Scherofluron-d6; Cortineff-d6; Florinef acetate-d6; Alflorone acetate-d6; (11β)-21-(Acetyloxy)-9-fluoro-11,17-dihydroxypregn-4-ene-3,20-dione-d6; 9-Fluorohydrocortisone Acetate-d6; 9α-Fluorocortisol 21-Acetate-d6. Grade: 99% by CP; 98% atom D. Molecular formula: C23H25D6FO6. Mole weight: 428.53.
Fludrocortisone-[d5]
Fludrocortisone-[d5] is a deuterium labelled form of Fludrocortisone. Fludrocortisone is a corticosteroid used to treat adrenogenital syndrome, postural hypotension, and adrenal insufficiency. Synonyms: (11β)-9-Fluoro-11,17,21-trihydroxypregn-4-ene-3,20-dione-d5; 9α-Fluorohydrocortisone-d5; 9α-Fluoro-17-hydroxycorticosterone-d5; Fluohydrisone-d5; Astonin H-d5. Grade: >97%. Molecular formula: C21H24D5FO5. Mole weight: 385.48.
Fludrocortisone-d5 Acetate
Fludrocortisone-d5 Acetate is a labelled analogue of Fludrocortisone. Fludrocortisone is an artificially synthesized form of glucocorticoid that is used to treat adrenogenital syndrome, hypotension, as well as adrenocortical insufficiency in combination with other medications. Grade: > 95%. Molecular formula: C23H26FO6D5. Mole weight: 427.53.
Fludrocortisone-[d6]
Fludrocortisone-[d6] is a deuterium labelled form of Fludrocortisone. Fludrocortisone is a corticosteroid used to treat adrenogenital syndrome, postural hypotension, and adrenal insufficiency. Synonyms: (11β)-9-Fluoro-11,17,21-trihydroxypregn-4-ene-3,20-dione-d6; 9α-Fluorohydrocortisone-d6; 9α-Fluoro-17-hydroxycorticosterone-d6; Fluohydrisone-d6. Grade: 95% by CP; 98% atom D. Molecular formula: C21H23D6FO5. Mole weight: 386.49.
Fluensulfone
Fluensulfone is a nematicide of the 1,3-thiazole class. Fluensulfone is used in agriculture for the control of a variety of plant parasitic nematodes. Synonyms: 5-chloro-2-(3,4,4-trifluorobut-3-ene-1-sulfonyl)-1,3-thiazole; 5-Chloro-2-[(3,4,4-trifluoro-3-buten-1-yl)sulfonyl]thiazole. Grade: 95%. CAS No. 318290-98-1. Molecular formula: C7H5ClF3NO2S2. Mole weight: 291.687.
Fluensulfone
Fluensulfone is a new nematicide for chemical control of plant parasitic nematodes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MCW-2. CAS No. 318290-98-1. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-107771.
Flufenacet
Flufenacet. Group: Biochemicals. Alternative Names: Fluthiamid; Fluthiamide; Thiafluamide; BAY-FOE 5043; Define DF; FOE 5043; N-(4-Fluorophenyl)-N-(1-methylethyl)-2-[[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]oxy]acetamide. Grades: Highly Purified. CAS No. 142459-58-3. Pack Sizes: 250mg. Molecular Formula: C14H13F4N3O2S, Molecular Weight: 363.33. US Biological Life Sciences.
Worldwide
Flufenacet ESA sodium salt
analytical standard. Group: Method and regulation specific.
Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca2+ channels, modulating non-selective cation channels (NSC), activating K+ channels. Flufenamic acid binds to the central pocket of TEAD2 YBD and inhibits both TEAD function and TEAD-YAP-dependent processes, such as cell migration and proliferation. Uses: Designed for use in research and industrial production. Additional or Alternative Names: inf1837;Lanceat;Meralen;N-((m-Trifluoromethyl)phenyl)-2-aminobenzoic acid;N-(alpha,alpha,alpha-Trifluoro-m-tolyl)anthranilate;n-(alpha,alpha,alpha-trifluoro-m-tolyl)-anthranilicaci;n-(m-trifluoromethylphenyl)-2-aminobenzoicacid;Nichisedan. Product Category: Inhibitors. CAS No. 530-78-9. Molecular formula: C14H10F3NO2. Mole weight: 281.23. Purity: 0.9985. Product ID: ACM530789. Alfa Chemistry ISO 9001:2015 Certified.
Flufenamic acid
Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase ( COX ), activates AMPK , and also modulates ion channels, blocking chloride channels and L-type Ca 2+ channels , modulating non-selective cation channels ( NSC ), activating K + channels. Flufenamic acid binds to the central pocket of TEAD2 YBD and inhibits both TEAD function and TEAD-YAP-dependent processes, such as cell migration and proliferation. Uses: Scientific research. Group: Signaling pathways. CAS No. 530-78-9. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1221.
Flufenamic acid
Flufenamic Acid is an anti-inflammatory agent, and also acts as an ion channel modulator. Synonyms: Flufenamic Acid; CI-440; CN-27554; INF-1837; CI 440; CN 27554; INF 1837; CI440; CN27554; INF1837. Grade: >98%. CAS No. 530-78-9. Molecular formula: C14H10F3NO2. Mole weight: 281.23.
Flufenamic Acid
Anti-inflammatory; analgesic. Group: Biochemicals. Alternative Names: 2-[[3- (Trifluoromethyl) phenyl]amino]benzoic Acid; 2-[3- (Trifluoromethyl) anilino]benzoic Acid; 3'-Trifluoro methyl diphenylamine-2-carboxylic Acid; Fullsafe; INF 1837; Meralen; Sastridex; Surika; Tecramine. Grades: Highly Purified. CAS No. 530-78-9. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
Flufenamic acid-[13C6]
Flufenamic acid-[13C6] is the labelled analogue of Flufenamic acid, which is a nonsteroidal anti-inflammatory drug. Synonyms: Flufenamic acid-13C6; 2-(3-Trifluoromethyl-phenylamino)-13C6-benzoic acid; 2-[3-(Trifluoromethyl)anilino]benzoic Acid-13C6; 3'-Trifluoromethyldiphenylamine-2-carboxylic Acid-13C6; Fullsafe-13C6; Meralen-13C6; Sastridex-13C6; Surika-13C6; Tecramine-13C6; Flufenamic acid-(benzoic ring-13C6). Grade: 95% by HPLC; 98% atom 13C. CAS No. 1325559-30-5. Molecular formula: C8[13C]6H10F3NO2. Mole weight: 287.19.
Flufenamic acid-(benzoic ring-13C6)
analytical standard. Group: Opiates / synthetic analgesic drug standards.
Flufenamic acid butyl ester
Flufenamic acid butyl ester. Group: Biochemicals. Alternative Names: ufenamate. Grades: Highly Purified. CAS No. 67330-25-0. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C18H18F3NO2. US Biological Life Sciences.
Worldwide
Flufenamic Acid Glucuronide
Flufenamic Acid Glucuronide is a metabolite of Flufenamic acid, an anti-inflammatory and analgesic agent. Synonyms: 1-[2-[[3-(Trifluoromethyl)phenyl]amino]benzoate]-β-D-glucopyranuronic Acid. Grade: 95%. CAS No. 87816-74-8. Molecular formula: C20H18F3NO8. Mole weight: 457.35.
Flufenoxuron is a chitin synthesis inhibitor that is used as a benzoylurea insecticide. Flufenoxuron decreases chitin synthesis, molting, and egg hatching, preventing development in insects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 101463-69-8. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-B2009.
Flufiprole is a non-systemic phenylpyrazole insecticide targeting the GABA receptor. It is used in the rice field and performs well in controlling a variety of pests. Synonyms: 1-[2,6-Dichloro-4-(trifluoromethyl)phenyl]-5-[(2-methyl-2-propen-1-yl)amino]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile; Butene-fipronil; Butylene-fipronil; Flupiprole; Rizazole; 1-(2,6-Dichloro-α,α,α-trifluoro-p-tolyl)-5-(2-methylallylamino)-4-(trifluoromethylsulfinyl)pyrazole-3-carbonitrile. Grade: ≥95%. CAS No. 704886-18-0. Molecular formula: C16H10Cl2F6N4OS. Mole weight: 491.24.
Flugestone 17-acetate
Flugestone 17-acetate. Group: Biochemicals. Alternative Names: (11b)-17-(Acetyloxy)-9-fluoro-11-hydroxy-pregn-4-ene-3,20-dione; 17a-Acetoxy-9a-fluoro-11b-hydroxy-pregn-4-ene-3,20-dione; 17a-Acetoxy-9a-fluoro-11b-hydroxyprogesterone. Grades: Highly Purified. CAS No. 2529-45-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C23H31FO5. US Biological Life Sciences.
Worldwide
Fluifort
Fluifort is used in anti-cancer treatment as a selective scavenger of reactive oxygen intermediates. Synonyms: S-(Carboxymethyl)-L-cysteine compd. with L-lysine. Grade: > 95%. CAS No. 49673-81-6. Molecular formula: C11H23N3O6S. Mole weight: 325.38.
Fluindapyr
Fluindapyr is a broad-spectrum pyrazolamide chiral fungicide of succinate dehydrogenase inhibitor ( SDHIs ) with broad bactericidal spectrum and good efficacy. Fluopimomide is effective against M. incognita in vitro and application of fuopimomide shows some growth promotion effect in cucumber [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1383809-87-7. Pack Sizes: 5 mg. Product ID: HY-W753375.
Fluindione
Fluindione. Group: Biochemicals. Alternative Names: 2-(4-Fluorophenyl)-1H-indene-1,3(2H)-dione; 2-(p-Fluorophenyl)-1,3-indandione; LM 123. Grades: Highly Purified. CAS No. 957-56-2. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C15H9FO2. US Biological Life Sciences.
Worldwide
Fluindione
Fluindione is a vitamin K antagonist with anticoagulant applications. It is under investigation for the treatment of venous thrombosis, pulmonary embolism, permanent atrial fibrillation, and blood coagulation disorders. Uses: Anticoagulants. Synonyms: 2-(4-fluorophenyl)indene-1,3-dione. CAS No. 957-56-2. Molecular formula: C15H9FO2. Mole weight: 240.233.
Fluindione-[d4]
Fluindione-[d4] is the labelled analogue of Fluindione, which is a vitamin K antagonist with anticoagulant applications. Synonyms: Fluindione D4; 2-(4-Fluorophenyl)-1H-indene-1,3(2H)-dione-d4; 2-(p-Fluorophenyl)-1,3-indandione-d4; LM 123-d4; Previscan-d4; 2-[4-Fluoro(2H4)phenyl]-1H-indene-1,3(2H)-dione. Grade: 95% by HPLC; 95% atom D. CAS No. 1246820-41-6. Molecular formula: C15H5D4FO2. Mole weight: 244.25.
Flukabrand selectophore,hydrogen*ionoph ore iv
Flukabrand selectophore,hydrogen*ionoph ore iv. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Octadecyl isonicotinate, Proton ionophore IV, Hydrogen ionophore IV, ETH 1778, 103225-02-1, 4-Pyridinecarboxylicacid, octadecyl ester, 4-Pyridinecarboxylic acid, octadecyl ester, AC1LAPF5, ACMC-20m63r, SureCN3128513, CHEMBL116833, octadecyl pyridine-4-carboxylate, 95296_FLUKA, CTK4A1889, Isonicotinic acid octadecyl ester, AG-D-13722, ETH 1778;Octadecyl 4-pyridinecarboxylate; Octadecyl isonicotinate. Product Category: Heterocyclic Organic Compound. CAS No. 103225-02-1. Molecular formula: C24H41NO2. Mole weight: 375.59. Purity: 0.96. IUPACName: octadecyl pyridine-4-carboxylate. Canonical SMILES: CCCCCCCCCCCCCCCCCCOC(=O)C1=CC=NC=C1. Density: 0.936g/cm³. Product ID: ACM103225021. Alfa Chemistry ISO 9001:2015 Certified.
Flumatinib
Flumatinib is a multi-kinase inhibitor of c-Abl, PDGFRβ and c-Kit with IC50 values of 1.2 nM, 307.6 nM and 2662 nM respectively. It can predominantly inhibit the autophosphorylation of Bcr-Abl in K562 cell in vitro. It can inhibit the phosphorylation of c-Kit in Mo7e cell and the phosphorylation of PDGFR in Swiss3T3 cell in higher concentration. It has no or little effect on other tyrosine kinase including EGFR, KDR, c-Src andHER2. It can reduce the expression of C-MYC, HIF-1 α and VEGF in U266 cell line in a time- and dose-dependent manners. It effectively overcame the drug resistance of certain KIT mutants with activation loop mutations. It was developed by Jiangsu Hansoh Pharmaceutical Co., Ltd. and is currently in Phase III clinical trials in China for the treatment of chronic myelogenous leukemia (CML). Uses: Flumatinib is used for the treatment of chronic myelogenous leukemia (cml). Synonyms: 4-[(4-methylpiperazin-1-yl)methyl]-N-(6-methyl-5-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}pyridin-3-yl)-3-(trifluoromethyl)benzamide; HH-GV678; HHGV678; HH GV678; 4-[(4-Methyl-1-piperazinyl)methyl]-N-(6-methyl-5-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}-3-pyridinyl)-3-(trifluoromethyl)benzamide. Grade: >98%. CAS No. 895519-90-1. Molecular formula: C29H29F3N8O. Mole weight: 562.59.
Flumatinib
Flumatinib (HHGV678) is an orally available, selective inhibitor of Bcr-Abl. Flumatinib inhibits c-Abl , PDGFRβ and c-Kit with IC 50 s of 1.2 nM, 307.6 nM and 665.5 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HHGV678. CAS No. 895519-90-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13904.
Flumatinib mesylate
Flumatinib (HHGV678) mesylate is an orally active and selective inhibitor of Bcr-Abl. Flumatinib mesylate inhibits c-Abl, PDGFRβ and c-Kit with IC 50 values of 1.2, 307.6 and 665.5 nM, respectively. Flumatinib mesylate inhibits Bcr-Abl autophosphorylation and Stat5 and Erk1/2 phosphorylation. Flumatinib mesylate inhibits tumor growth in chronic myelogenous leukemia model [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HHGV678 mesylate. CAS No. 895519-91-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13905.
Flumatinib Mesylate
Flumatinib mesylate, a derivative of imatinib, is a multi-kinase inhibitor for c-Abl, PDGFRβ and c-Kit. It is currently in Phase I and II clinical trials in China for the treatment of chronic myelogenous leukemia (CML). It effectively overcomes drug resistance of certain KIT mutants. It can reduce the expression of C-MYC, HIF-1 α and VEGF in U266 cell line in a time- and dose-dependent manners. Synonyms: HH-GV-678 mesylate. Grade: >98%. CAS No. 895519-91-2. Molecular formula: C30H33F3N8O4S. Mole weight: 658.69.
Flumatinib Mesylate-d3
One of the isotopic labelled salt of Flumatinib, which is a selective inhibitor of BCR-ABL/PDGFR/KIT. Synonyms: N-(6-methyl-5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)pyridin-3-yl)-4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzamide Mesylate-d3. Molecular formula: C29H26F3N8OD3.CH6O3S. Mole weight: 663.74.
Flumatinib Mesylate Impurity 1
Flumatinib Mesylate Impurity 1 is an impurity of Flumatinib Mesylate, a targeted therapy drug employed to treat chronic myeloid leukemia (CML). Synonyms: 4-((4-Methylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)benzoic acid. Grade: > 95%. CAS No. 859027-02-4. Molecular formula: C14H17F3N2O2. Mole weight: 302.30.
Flumatinib Mesylate Impurity 1-d3
One of the isotopic labelled impurities of Flumatinib, which is a selective inhibitor of BCR-ABL/PDGFR/KIT. Synonyms: 4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzoic acid-d3. Molecular formula: C14H14F3N2O2D3. Mole weight: 305.32.
Flumazenil
Flumazenil is a competitive GABAA receptor antagonist, used in the treatment of benzodiazepine overdoses. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 15-1788. CAS No. 78755-81-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0009.
Flumazenil
Imidazodiazepine which selectively blocks the central effects of classic benzodiazepines. It is used as benzodiazepine antagonist. Group: Biochemicals. Alternative Names: 8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic Acid Ethyl Ester; Anexate; Flumazepil; Flumenazil; Lanexat; Mazicon; Ro 15-1788; Ro 15-1788/000; Ro 151788; Ro 1722; Ro 41-8157; Romazicon. Grades: Highly Purified. CAS No. 78755-81-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Flumazenil
25mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C15H14FN3O3. CAS No. 78755-81-4. Prepack ID 90029044-25mg. Molecular Weight 303.29. See USA prepack pricing.
Flumazenil EP Impurity B
Flumazenil EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ethyl 8-hydroxy-5-methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate. CAS No. 131666-45-0. Molecular formula: C15H15N3O4. Mole weight: 301.3. Catalog: APB131666450.
A competitive blocker of benzodiazepine activation of inhibitory GABAergic synpases (ID50 = 200ug/kg/i.p). Binds to the benzodiazepine site of GABAA receptors. Enhances GABAA-receptor mediated currents and antagonizes the enhancing effects of benzodiapine agonist flurazepam. Exhibits fast association and dissociation from the benzodiazepine binding site. Permeates the blood brain barrier, however, the level of uptake may depend on efflux effects of p-glycogprotein transporter. Group: Biochemicals. Grades: Highly Purified. CAS No. 78755-81-4. Pack Sizes: 10mg. Molecular Formula: C??H??FN?O?. US Biological Life Sciences.
Worldwide
Flumazenil Impurity 12
Flumazenil Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1248271-71-7. Molecular formula: C10H11FN2O3. Mole weight: 226.21. Catalog: APB1248271717.
Flumazenil Liposome
Flumazenil is a 1,4-imidazole benzodiazepine derivative and a benzodiazepine (BZD) receptor antagonist. This product is a pre-formulated liposome with flumazeni. It is only for research purposes and for the injection to laboratory animals. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes.
Flumazenil Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.