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Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis) [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 154445-77-9. Pack Sizes: 10 g; 25 g; 50 g; 100 g. Product ID: HY-Y1636.
Fmoc-Arg(Pbf)-OH (U-13C6 , U-15N4)
Fmoc-Arg(Pbf)-OH (U-13C6 , U-15N4). Uses: Peptide synthesis. Additional or Alternative Names: L-Arginine-13C6,15N4 Na-Fmoc-Nw-Pbf derivative. Product Category: Amino Acids. CAS No. 1217461-89-6. Molecular formula: Pbf15NH13C(=15NH)15NH(13CH2)313CH(15NH-Fmoc)13COOH. Mole weight: 658.7. Purity: 99 atom % 13C 98 atom % 15N. Canonical SMILES: Cc1c(C)c(c(C)c2CC(C)(C)Oc12)S(=O)(=O)[15NH][13C](=[15NH])[15NH][13CH2][13CH2][13CH2][13C@H]([15NH]C(=O)OCC3c4ccccc4-c5ccccc35)[13C](O)=O. Product ID: ACM1217461896-2. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-arg(pbf)-opfp
Fmoc-arg(pbf)-opfp. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-α-Fmoc-NG-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-argininepentafluorophenylester;N-alpha-Fmoc-N-gamma-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine pentafluorophenyl ester;Fmoc-Arg(Pbf)-OPfp;(S)-perfluorophenyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-5-(3-(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-ylsulfonyl)guanidino)pentanoate;Fmoc-Nw-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine pentafluorophenyl ester;FMoc-Arg(Pbf)-OPfp ( FMoc-Arg(Pbf)-OPfp );Fmoc-Arg(Pbf)-OPfp technical, >=80% (HPLC). Product Category: Heterocyclic Organic Compound. CAS No. 200132-16-7. Molecular formula: C40H39F5N4O7S. Mole weight: 814.825. Product ID: ACM200132167. Alfa Chemistry ISO 9001:2015 Certified.
An excellent derivative for the introduction of Arg in Fmoc SPPS. The Pmc group is removed by TFA in 1-3 hours. In the synthesis of peptides containing both Arg and Trp, it is recommended that this derivative is used in conjunction with Fmoc-Trp(Boc)-OH. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Arg(Pmc)-OH, N-α-Fmoc-N G-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-L-arginine. Product Category: Amino Acids. CAS No. 119831-72-0. Mole weight: 662.8. Product ID: ACM119831720. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Arg(Pmc)-OH
Fmoc-Arg(Pmc)-OH. Group: Biochemicals. Grades: Highly Purified. CAS No. 119831-72-0. Pack Sizes: 2g, 5g, 10g, 25g, 50g. US Biological Life Sciences.
Worldwide
Fmoc-Asn(Ac?AcNH-ß-Glc)-OH
An excellent derivative for the introduction of an Asn(AcNH-β-Glc) residue by Fmoc SPPS. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Asn(Ac3AcNH-ß-Glc)-OH, N-α-Fmoc-N-β-[3,4,6-tri-O-acetyl-2-(acetylamino)-deoxy-2-β-glucopyranosyl]-L-asparagine. Product Category: Amino Acids. CAS No. 131287-39-3. Mole weight: 683.66. Product ID: ACM131287393-1. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Asn(Dmcp)-OH
A superior derivative to Fmoc-Asn(Trt)-OH for the synthesis of Asn-containing peptides by Fmoc SPPS. Fmoc-Asn(Dmcp)-OH is more soluble in DMF than Fmoc-Asn(Trt)-OH, thereby facilitating coupling reactions at higher concentration. Cleavage of the Dmcp group is rapid, even when the residue is located at the N-terminus of a peptide. Coupling of Dmcp-protected derivatives is faster than that of the corresponding hindered Trt derivatives. Dmcp-protected peptides have enhanced solubility. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Asn(Dmcp)-OH, N-α-Fmoc-N-β-(1-cyclopropyl-1-methylethyl)-L-asparagine. Product Category: Amino Acids. CAS No. 172947-19-2. Mole weight: 436.5. Product ID: ACM172947192. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-asn(mtt)-opfp
Fmoc-asn(mtt)-opfp. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FMOC-ASPARAGINE(MTT)-OPFP;FMOC-ASN(MTT)-OPFP;FMOC-N-GAMMA-4-METHYLTRITYL-L-ASPARAGINE PENTAFLUOROPHENYL ESTER. Product Category: Heterocyclic Organic Compound. CAS No. 200259-55-8. Molecular formula: C45H33F5N2O5. Mole weight: 776.77. Product ID: ACM200259558. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Asn-OH
Building block for introduction of asparagine by Fmoc SPPS. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Asn-OH, N-α-Fmoc-L-asparagine. Product Category: Amino Acids. CAS No. 71989-16-7. Mole weight: 354.36. Product ID: ACM71989167. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Asn-OH-15N2
Fmoc-Asn-OH-15N2. Uses: Peptide synthesis. Additional or Alternative Names: N-(9-Fluorenylmethoxycarbonyl)-L-asparagine-15N2, L-Asparagine-15N2, α-N-Fmoc derivative. Product Category: Amino Acids. CAS No. 287484-42-8. Molecular formula: H215NCOCH2CH(15NH-Fmoc)CO2H. Mole weight: 356.34. Canonical SMILES: [15NH2]C(=O)C[C@H]([15NH]C(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O. Product ID: ACM287484428. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Asn-OPfp
Fmoc-Asn-OPfp. Group: Biochemicals. Grades: Highly Purified. CAS No. 86060-99-3. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences.
Synonyms: N-(fluorenylmethoxycarbonyl)-N4-trityl-L-asparagyl-glycine; N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-beta-trityl-L-asparaginyl-glycine; Glycine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-L-asparaginyl-; N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-trityl-L-asparaginylglycine. Grades: ≥95% by HPLC. CAS No. 1260093-07-9. Molecular formula: C40H35N3O6. Mole weight: 653.72.
Fmoc-Asn(Trt)-OH
Fmoc-Asn(Trt)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Fmoc-Asn(Trt)-OH can be used for synthesis of Fmoc-based solid-phase peptide synthesis [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 132388-59-1. Pack Sizes: 10 mM * 1 mL; 25 g. Product ID: HY-W002327.
Fmoc-Asn(Trt)-OH
Fmoc-Asn(Trt)-OH. Group: Biochemicals. Alternative Names: N-Alpha-Fmoc-N-beta-trityl-L-asparagine; Fmoc-Asn(Trt)-OH. Grades: Highly Purified. CAS No. 132388-59-1. Pack Sizes: 25g, 50g, 100g, 250g. Molecular Formula: C38H32N2O5, Molecular Weight: 596.67. US Biological Life Sciences.
Worldwide
FMOC-Asn(Trt)-OH
High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Fmoc-Asn(Trt)-OH has good solubility properties in most organic solvents, and its use has been shown to result in significantly purer peptides than other derivatives used for the introduction of Asn. Coupling can be performed by standard procedures. The trityl group is normally removed by 95% TFA in 1-3 hours, with no alkylation of Trp residues. When Asn(Trt) is the N-terminal residue, the reaction time may need to be extended to ensure complete deprotection. Literature references P. Sieber, et al. in 'Innovation & Perspectives in Solid Phase Synthesis, 1st International Symposium', R. Epton (Eds), SPCC UK Ltd., Birmingham, 1990, pp. 577. P. Sieber, et al. (1991) Tetrahedron Lett., 32, 739. M. Friede, et al. (1992) Pept. Res., 5, 145. Uses: Fmoc-asn(trt)-oh has diverse applications in scientific experiments. it is commonly used in peptide synthesis, where it is used as a building block to assemble longer peptides. other applications include generating specific peptide sequences for biological studies, designing new drugs, and studying protein interactions. Additional or Alternative Names: FMOC-Asn(Trt)-OH, N-α-Fmoc-N-β-trityl-L-asparagine. Product Category: Amino Acids. CAS No. 132388-59-1. Molecular formula: C38H32N2O5. Mole weight: 596.67. Cano
This pseudoproline dipeptide is undoubtedly the most effective and simplest to use tool for overcoming aggregation and enhancing peptide quality in Fmoc SPPS for peptide containing the Asn-Ser dipeptide motif. It consists of a dipeptide in which the serine residue has been reversibly protected as a structure-breaking proline-like TFA-labile oxazolidine. The reason pseudoproline residue is introduced as a dipeptide is because it avoids the need to acylate the hindered oxazolidine nitrogen. This has the added advantage of extending the peptide chain by two residues in one step. The serine residue is regenerated during the normal TFA-mediated cleavage reaction. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Asn(Trt)-Ser(psiMe,Mepro)-OH. Product Category: Amino Acids. CAS No. 920519-33-1. Mole weight: 723.81. Product ID: ACM920519331-1. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-aspartol(obut). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Fmoc-Aspartol(OBut);N-alpha-(9-Fluorenylmethyloxycarbonyl)-beta-tert-butyl-L-aspartimol;N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-beta-trityl-L-asparaginol. Product Category: Heterocyclic Organic Compound. CAS No. 161529-14-2. Molecular formula: C23H27NO5. Mole weight: 397.46. Product ID: ACM161529142. Alfa Chemistry ISO 9001:2015 Certified. Categories: 1820583-73-0.
Fmoc-Asp-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: Fmoc-L-Isoasparagine; Fmoc-Isoasn-OH; Butanoic acid, 4-amino-3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-4-oxo-, (3S)-. Grades: ≥98.0%. CAS No. 200335-40-6. Molecular formula: C19H18N2O5. Mole weight: 354.36.
Fmoc-Asp(O-2-PhiPr)-OH
Quasi-orthogonally-protected Asp derivative.The 2-PhiPr group can be removed selectively in the presence of tBu-based protecting groups by treatment with 1% TFA in DCM , making this derivative an extremely useful tool for the preparation of cyclic peptides by Fmoc SPPS. or for library synthesis. For the on-resin synthesis of side-chain to side-chain lactam bridged peptides, the combination of Lys(Mtt) and Asp(O-2-PhiPr) is particularly advantageous since both side-chains can be simultaneously unmasked in a single step.This derivative has also been used in solution to prepare bicyclic helix initiating peptides. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Asp(O-2-PhiPr)-OH, N-α-Fmoc-L-aspartic acid β-2-phenylisopropyl ester. Product Category: Amino Acids. CAS No. 200336-86-3. Mole weight: 473.52. Product ID: ACM200336863-1. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Asp-OAll
Orthogonally-protected building block for the synthesis of head-to-tail cyclic peptides by Fmoc SPPS. The α-allyl ester can be selectively removed in the presence of Fmoc- and tBu-based protecting groups by treatment with Pd(Ph3P)4/ CHCl3/AcOH/NMM , thereby facilitating the synthesis of branched esters, amides, lactones and lactams incorporating an aspartyl unit. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Asp-OAll, N-α-Fmoc-L-aspartic acid α-allyl ester. Product Category: Amino Acids. CAS No. 144120-53-6. Molecular formula: C22H21NO6. Mole weight: 395.41. Product ID: ACM144120536. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Asp(OAll)-OH
Orthogonally-protected building block for the synthesis of peptides modified at the Asp side chain by Fmoc SPPS. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Asp(OAll)-OH. Product Category: Amino Acids. CAS No. 146982-24-3. Mole weight: 395.41. Product ID: ACM146982243. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Asp(OAll)-OH
Fmoc-Asp(OAll)-OH is an aspartic acid derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 146982-24-3. Pack Sizes: 10 g; 25 g; 50 g; 100 g. Product ID: HY-W008075.
Fmoc-Asp-Obzl is an aspartic acid derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 86060-83-5. Pack Sizes: 5 g; 10 g; 25 g; 100 g. Product ID: HY-W008360.
Fmoc-Asp(OBzl)-OH
High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Asp(OBzl)-OH, N-α-Fmoc-L-aspartic acid β-benzyl ester. Product Category: Amino Acids. CAS No. 86060-84-6. Mole weight: 445.46. Product ID: ACM86060846. Alfa Chemistry ISO 9001:2015 Certified. Categories: DTXSID50553435.
Fmoc-Asp(ODmab)-OH
Quasi-orthogonally-protected Asp derivative. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Asp(ODmab)-OH, N-α-Fmoc-L-aspartic acid β-4-{N-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]-amino} benzyl ester. Product Category: Amino Acids. CAS No. 269066-08-2. Mole weight: 666.76. Product ID: ACM269066082-1. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Asp(ODMAB)-OH
Fmoc-Asp(ODMAB)-OH is an aspartic acid derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 269066-08-2. Pack Sizes: 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-W007108.
Fmoc-Asp-OH-15N
Fmoc-Asp-OH-15N. Uses: Peptide synthesis. Additional or Alternative Names: N-(9-Fluorenylmethoxycarbonyl)-L-aspartic-15N acid, L-Aspartic-15N acid, N-Fmoc derivative. Product Category: Amino Acids. CAS No. 287484-33-7. Molecular formula: HO2CCH2CH(15NH-Fmoc)CO2H. Mole weight: 356.33. Canonical SMILES: OC(=O)C[C@H]([15NH]C(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O. Product ID: ACM287484337-1. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Asp-OH-2-13C
Fmoc-Asp-OH-2-13C. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Fmoc-Asp-OH-2-13C, L-Aspartic-2-13C acid, N-Fmoc dervative, N-(9-Fluorenylmethoxycarbonyl)-L-aspartic-2-13C acid, 286460-78-4. Product Category: Heterocyclic Organic Compound. CAS No. 286460-78-4. Molecular formula: C19H17NO6. Mole weight: 356.33. Purity: 0.96. IUPACName: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)butanedioic acid. Canonical SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC(=O)O)C(=O)O. Product ID: ACM286460784. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Asp(OH)-OtBu
Fmoc-Asp(OH)-OtBu. Group: Biochemicals. Grades: Highly Purified. CAS No. 129460-09-9. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C23H25NO6. US Biological Life Sciences.
Worldwide
Fmoc-asp-ome
Fmoc-asp-ome. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Fmoc-Asp-OMe;N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-aspartic acid alpha-methyl ester;Fmoc-L-Aspartic acid alpha-methyl ester;Fmoc-L-Asp-OMe. Product Category: Heterocyclic Organic Compound. CAS No. 145038-52-4. Molecular formula: C20H19NO6. Mole weight: 369.37. Product ID: ACM145038524. Alfa Chemistry ISO 9001:2015 Certified. Categories: (S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-methoxy-4-oxobutanoic acid.
Fmoc-Asp-OtBu
Selectively protected building block for library synthesis or the preparation of β-aspartyl peptides by Fmoc SPPS. After condensation of the side-chain carboxy with an appropriate amine or alcohol, the β-amino and carboxy functions can be selectively unmasked with 20% piperidine in DMF and 50% TFA in DCM respectively, facilitating the synthesis of branched esters and amides, and lactams and lactones containing the aspartyl unit. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Asp-OtBu, N-α-Fmoc-L-aspartic acid α-t.-butyl ester. Product Category: Amino Acids. CAS No. 129460-09-9. Molecular formula: C23H25NO6. Mole weight: 411.45. Product ID: ACM129460099. Alfa Chemistry ISO 9001:2015 Certified. Categories: (S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(tert-butoxy)-4-oxobutanoic acid.
Fmoc-Asp-OtBu
Fmoc-Asp-OtBu is an aspartic acid derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 129460-09-9. Pack Sizes: 5 g; 10 g. Product ID: HY-W010959.
Fmoc-Aaa-(Dmb)Gly-OH dipeptides offer the same benefits as pseudoproline dipeptides in Fmoc SPPS but for peptide sequences containing Gly. They are extremely easy to use. Standard coupling methods like PyBOP/DIPEA or DIPCDI/HOBt can be used for their introduction. Removal of the Dmb group and regeneration of the glycine residue occurs during the course of standard TFA-mediated cleavage reaction. This derivative also completely inhibits aspartimide formation. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Asp(OtBu)-(Dmb)Gly-OH, N-α-Fmoc-β-O-t.-butyl-L-aspartyl-N-α-(2,4-dimethoxybenzyl)-glycine. Product Category: Amino Acids. CAS No. 900152-72-9. Mole weight: 618.67. Product ID: ACM900152729. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Asp(OtBu)-OH. Group: Biochemicals. Alternative Names: Fmoc-L-aspartic acid b-tert-butyl ester. Grades: Highly Purified. CAS No. 71989-14-5. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C23H25NO6. US Biological Life Sciences.
Worldwide
Fmoc-Asp(OtBu)-OH
High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Standard building block for introduction of aspartic acid amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Asp(OtBu)-OH, N-α-Fmoc-L-aspartic acid β-t.-butyl ester. Product Category: Amino Acids. CAS No. 71989-14-5. Molecular formula: C23H25NO6. Mole weight: 411.45. Product ID: ACM71989145-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: Fmoc-L-Asp(OtBu)-OH.
Fmoc-Asp(OtBu)-OH
Fmoc-Asp(OtBu)-OH. CAS No: 71989-14-5
Sarchem Laboratories New Jersey NJ
Fmoc-Asp(OtBu)-OH
Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is an aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis [1]. Uses: Scientific research. Group: Peptides. Alternative Names: 4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate; Fmoc-L-Asp(OtBu)-OH. CAS No. 71989-14-5. Pack Sizes: 100 g; 500 g. Product ID: HY-Y1169.
Fmoc-Asp(OtBu)-OH-15N. Uses: Peptide synthesis. Additional or Alternative Names: L-Aspartic-15N acid, N-Fmoc, 4-tert-butyl ester. Product Category: Amino Acids. CAS No. 1217457-38-9. Molecular formula: t-Bu-O2CCCH2CH(15NH-Fmoc)CO2H. Mole weight: 412.44. Canonical SMILES: CC(C)(C)OC(=O)C[C@H]([15NH]C(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O. Product ID: ACM1217457389. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Asp(OtBu)-OH (U-13 C4, 15N)
Fmoc-Asp(OtBu)-OH-13C4,15N is the 13C and 15N labeled Fmoc-Asp(OtBu)-OH[1]. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is an aspartate derivative containing amine-protecting group Fmoc. Uses: Fmoc-asp(otbu)-oh can be used for peptide synthesis. Product Category: Amino Acids. CAS No. 1160760-08-6. Molecular formula: (CH3)3COO13C13CH213CH(15NH-Fmoc)13COOH. Mole weight: 416.4. Purity: Peak Area by HPLC ≥95%. Canonical SMILES: CC(C)(C)O[13C](=O)[13CH2][13C@@H]([13C](=O)O)[15NH]C(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13. Product ID: ACM1160760086. Alfa Chemistry ISO 9001:2015 Certified.
This pseudoproline dipeptide is undoubtedly the most effective and simplest to use tool for overcoming aggregation and enhancing peptide quality in Fmoc SPPS for peptide containing the Asp-Ser dipeptide motif. It consists of a dipeptide in which the serine residue has been reversibly protected as a structure-breaking proline-like TFA-labile oxazolidine. The reason pseudoproline residue is introduced as a dipeptide is because it avoids the need to acylate the hindered oxazolidine nitrogen. This has the added advantage of extending the peptide chain by two residues in one step. The serine residue is regenerated during the normal TFA-mediated cleavage reaction. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Asp(OtBu)-Ser(psiMe,Mepro)-OH. Product Category: Amino Acids. CAS No. 955048-92-7. Mole weight: 538.59. Product ID: ACM955048927. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Asp(OtBu)-Ser[Psi(Me,Me)Pro]-OH 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 955048-92-7. Pack Sizes: 1g, 5g, 10g. US Biological Life Sciences.
Worldwide
Fmoc-Asp(OtBu)-Thr(psiMe,Mepro)-OH
This pseudoproline dipeptide is undoubtedly the most effective and simplest to use tool for overcoming aggregation and enhancing peptide quality in Fmoc SPPS for peptide containing the Asp-Thr dipeptide motif. It consists of a dipeptide in which the threonine residue has been reversibly protected as a structure-breaking proline-like TFA-labile oxazolidine. The reason the pseudoproline residue is introduced as a dipeptide is because it avoids the need to acylate the hindered oxazolidine nitrogen. This has the added advantage of extending the peptide chain by two residues in one step. The threonine residue is regenerated during the normal TFA-mediated cleavage reaction. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Asp(OtBu)-Thr(psiMe,Mepro)-OH. Product Category: Amino Acids. CAS No. 920519-32-0. Mole weight: 552.62. Product ID: ACM920519320-1. Alfa Chemistry ISO 9001:2015 Certified.