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| Product | Description | |
|---|---|---|
| Forskolin (7b-Acetoxy-8,13-epoxy-1a,6b,9a-trihydroxy- labd-14-ene-11-one, Coleonol, Colforsin) | Forskolin is a naturally occurring diterpene from the Indian plant, Coleus forskohlii, that works as an activator of adenylate cyclase resulting in an increase in the intracellular concentration of cAMP. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 50mg. US Biological Life Sciences. |  Worldwide |
| Forskolin (7b-Acetoxy-8,13-epoxy-1a,6b,9a-trihydroxy- labd-14-ene-11-one, Colforsin) | Forskolin is a powerful activator of adenyklate cyclase, resulting in an increase of intracellular cAMP concentration.1,2 Activates adenylate cyclase leading to an increase in the intracellular concentration of cAMP. Widely used tool for the investigation of the role of cAMP as a second messenger with a broad range of potential therapeutic applications. Inotropic agent and vasodilator. Induces platelet aggregation. Inhibits ion channels by a mechanism that does not involve cAMP. Non-competitive inhibitor of nicotinic acetylcholine receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 10mg, 25mg, 100mg. US Biological Life Sciences. | Worldwide |
| Forskolin (7b-Acetoxy-8,13-epoxy-1a,6b,9a-trihydroxy-labd-14-ene-11-one, Colforsin) | Activates adenylate cyclase leading to an increase in the intracellular concentration of cAMP. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Forskolin (Boforsin, Colforsin, Coleonol, NSC 357088, NSC 375489) | Potent, cell permeable adenylyl cyclase activator. Increases intracellular cAMP levels. Widely used tool to investigate cAMP as a second messenger. Inotropic and antihypertensive. Smooth muscle relaxant/vasodilator. Glucose transporter inhibitor. Platelet aggregation inhibitor. Stimulates lipolysis in fat cells. Non-competitive nicotinic acetylcholine receptors inhibitor. MAP kinase inhibitor. Upregulates mitochondrial uncoupling protein (UCP) mRNA levels in brown adipose tissue. Autophagy inhibitor. Hedgehog signaling inhibitor. Has antiglaucoma potential. Promotes neuronal differentiation of NSCs. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 1mg, 5mg, 25mg, 50mg. US Biological Life Sciences. | Worldwide |
| Forskolin (Coleus forskohlii) | The major cell-permeable diterpene isolated from the Indian plant Coleus forskohlii. At low doses, it acts as a positive inotropic agent. At higher doses, it serves as a hypotensive and vasodilatory agent due to its actions as a smooth muscle relaxant. No major side effects are observed at effective doses. Forskolins pharmacological activities are due to its activation of adenylate cyclase (EC50 = 4uM), resulting in increased cAMP levels. The exact mechanism of forskolins positive inotropic effect is unknown but may be related to a cAMP-dependent increase in Na+ permeability that results in indirect augmentation of Ca2+ release. Inhibits MAP kinase in rat renal mesangial cells (IC50 = 25uM). Also acts as a Hh pathway antagonist. Shown to inhibit apoptosis in cerebellar granule cells and to induce apoptosis in resting human B lymphocytes. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Forskolin, Coleus forskohlii (7b-Acetoxy-8,13-epoxy-1α,6 β,9α-trihydroxy-labd-14-en-11-one, Colforsin) | The major cell-permeable diterpene isolated from the Indian plant Coleus forskohlii. At low doses, it acts as a positive inotropic agent. At higher doses, it serves as a hypotensive and vasodilatory agent due to its actions as a smooth muscle relaxant. No major side effects are observed at effective doses. Forskolins pharmacological activities are due to its activation of adenylate cyclase (EC50=4uM), resulting in increased cAMP levels. The exact mechanism of forskolins positive inotropic effect is unknown but may be related to a cAMP-dependent increase in Na+ permeability that results in indirect augmentation of Ca2+ release. Inhibits MAP kinase in rat renal mesangial cells (IC50= 25uM). Also acts as a Hh pathway antagonist. Shown to inhibit apoptosis in cerebellar granule cells and to induce apoptosis in resting human B lymphocytes. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 10mg, 25mg. Molecular Formula: C??H??O?. US Biological Life Sciences. | Worldwide |
| Forskolin Hemisuccinate | Forskolin Hemisuccinate is a derivative fo Forskolin (F701800), a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin Hemisuccinate was found to inhibit E-selectin gene transcription through a cAMP-dependent protein kinase pathway. Group: Biochemicals. Alternative Names: 1-[(3R, 4aR, 5S, 6S, 6aS, 10S, 10aR, 10bS)-3-Ethenyldodecahydro-6, 10, 10b-trihydroxy-3, 4a, 7, 7, 10a-pentamethyl-1-oxo-1H-naphtho[2, 1-b]pyran-5-yl] Ester Butanedioic Acid; 1H-Naphtho[2,1-b]pyran, Butanedioic Acid Deriv. Grades: Highly Purified. CAS No. 83797-56-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Forskolin Hemisuccinate-13C4 | Forskolin Hemisuccinate-13C4. Group: Biochemicals. Alternative Names: 1-[(3R, 4aR, 5S, 6S, 6aS, 10S, 10aR, 10bS)-3-Ethenyldodecahydro-6, 10, 10b-trihydroxy-3, 4a, 7, 7, 10a-pentamethyl-1-oxo-1H-naphtho[2, 1-b]pyran-5-yl] Ester Butanedioic Acid-13C4; 1H-Naphtho[2,1-b]pyran Butanedioic Acid Deriv.-13C4. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C2013C4H36O9, Molecular Weight: 472.51. US Biological Life Sciences. | Worldwide |
| Forssman antigen pentaose | Forssman Antigen Pentaose is a paramount compound, serving as an invaluable instrument for the scrutiny and assessment of Forssman antigens. Tailored meticulously, it can used to study the diseases correlating with the existence of Forssman antigens, inclusive of the enigmatic Forssman syndrome. Synonyms: GalNAc-a-1,3-GalNAc-b-1,3-Gal-a-1,4-Gal-b1,4Glc. Molecular formula: C34H58N2O26. Mole weight: 910.82. |  |
| Forssman antigen triaose | Forssman antigen triaose is an invaluable compound in the realm of biomedical inquiry, standing as a pivotal catalyst in the advancement of diagnostic assays and vaccines, specifically tailored to study the intricate nature of Forssman antigen-induced ailments. Synonyms: GalNAc-a-1,3-GalNAc-b-1,3-Gal. Molecular formula: C22H38N2O16. Mole weight: 586.54. | |
| Forsythin | Forsythin is purified from the fruits of Forsythia suspensa. Grades: >98%. CAS No. 96420-61-0. | |
| Forsythoside A | Forsythoside A. Group: Biochemicals. Alternative Names: Forsythiaside. Grades: Plant Grade. CAS No. 79916-77-1. Pack Sizes: 20mg. Molecular Formula: C29H36O15, Molecular Weight: 624.586999999999. US Biological Life Sciences. | Worldwide |
| Forsythoside A | Cas No. 79916-77-1. | |
| Forsythoside B | Forsythoside B. Group: Biochemicals. Grades: Plant Grade. CAS No. 81525-13-5. Pack Sizes: 20mg. Molecular Formula: C34H44O19, Molecular Weight: 756.7. US Biological Life Sciences. | Worldwide |
| Forsythoside E | Forsythoside E. Group: Biochemicals. Grades: Plant Grade. CAS No. 93675-88-8. Pack Sizes: 20mg. Molecular Formula: C20H30O12, Molecular Weight: 462.44. US Biological Life Sciences. | Worldwide |
| Forsythoside H | Forsythoside H. Group: Biochemicals. CAS No. 1178974-85-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Forsythoside I | Forsythoside I is a natural product isolated from forsythia suspense (thunb.) vahl, showing anti-inflammatory activities. Synonyms: Isoforsythoside A. Grades: 0.98. CAS No. 1177581-50-8. Molecular formula: C29H36O15. Mole weight: 624.59. | |
| Forsythoside I | Forsythoside I. Group: Biochemicals. CAS No. 1177581-50-8. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Fortimicin A | Produced by the strain of Micromonospora olivoasterospora, it has broad antibacterial spectrum and strong antibacterial activity, and is also effective to aminoglycoside antibiotic resistant bacteria producing 3'-phosphotransferase, 2''-nucleoside transferase, 6' and 2'-acetyltransferase. Synonyms: Astromicin; Astromicina; Astromicine; Astromicinum; Antibiotic KW-1070; 4-Amino-1-((aminoacetyl)methylamino)-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-lyxo-heptopyranosyl)-6-O-methyl-L-chiro-inositol. Grades: 95%. CAS No. 55779-06-1. Molecular formula: C17H35N5O6. Mole weight: 405.49. | |
| Fortimicin B | Produced by the strain of Micromonospora olivoasterospora, it has a weak antibacterial activity. Synonyms: Astromicin B; 4-Amino-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-lyxo-heptopyranosyl)-6-O-methyl-1-(methylamino)-L-chiro-inositol. CAS No. 54783-95-8. Molecular formula: C15H32N4O5. Mole weight: 348.44. | |
| Forward Reaction Buffer 10X | Foward reaction buffer (10X) for P4410. Group: Molecular Biology. Alternative Names: For use with T4 polynucleotide kinase. Pack Sizes: 400ul, 2x1ml. US Biological Life Sciences. | Worldwide |
| Fosalvudine tidoxil | Fosalvudine tidoxil is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Fosalvudine tidoxil is a prodrug derived from Alovudine (HY-B1516). Fosalvudine tidoxil is less toxic than Alovudine and can be used for the research of HIV-1 infection. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FOSALVUDINE TIDOXIL. Product Category: Inhibitors. CAS No. 763903-67-9. Molecular formula: C35H64FN2O8PS. Mole weight: 722.935. Canonical SMILES: O=P(OC[C@H]1O[C@@H](N(C(N2)=O)C=C(C)C2=O)C[C@@H]1F)(OCC(OCCCCCCCCCC)CSCCCCCCCCCCCC)O. Product ID: ACM763903679. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Fosamprenavir | Fosamprenavir, also called as GW433908, Lexiva and Telzir, is an oral prodrug of the protease inhibitor (PI) amprenavir. Combined with other antiretroviral agents, Fosamprenavir is indicated for the treatment of patients with HIV infection, particularly those who have not previously received antiretroviral therapy. Synonyms: [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-1-phenyl-3-phosphonooxybutan-2-yl]carbamate; 3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-(phenylmethyl)-2-(phosphonooxy)propyl)carbamic acid C-(tetrahydro-3-furanyl) ester; fosamprenavir; 226700-81-8 (calcium) GW 433908; GW-433908; GW-908. Grades: > 95%. CAS No. 226700-79-4. Molecular formula: C25H36N3O9PS. Mole weight: 585.62. | |
| Fosamprenavir | Fosamprenavir (Amprenavir phosphate;GW 433908) is a phosphate ester proagent of the antiretroviral protease inhibitor Amprenavir, with improved solubility [1]. Anti- HIV infection [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Amprenavir phosphate; GW 433908. CAS No. 226700-79-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-78726. |  |
| Fosamprenavir | {[(2R,3S)-1-{N-[2-(D3)methyl(D6)propyl]4-aminobenzenesulfonamido}-3-({[(3S)-oxolan-3-yloxy]carbonyl}amino)-4-phenylbutan-2-yl]oxy}phosphonic acid; ((3S)-Oxolan-3-yloxy)-N-((1S,2R)-3-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-1-benzyl-2-(phosphonooxy)propyl)carboxamide. therapeutic for diabetes insipidus, bedwetting, or nocturia. CAS No. 226700-79-4. Product ID: 8-04770. Molecular formula: C25H36N3O9PS. Mole weight: 585.61. |  |
| Fosamprenavir calcium | Calcium [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-1-phenyl-3-phosphonatooxy-butan-2-yl]carbamate. Protease inhibitor, anti-HIV agent. CAS No. 226700-81-8. Product ID: 2-08342. Molecular formula: C25H34CaN3O9PS. Mole weight: 623.67. Purity: 0.99. | |
| Fosamprenavir calcium | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Fosamprenavir calcium salt | Fosamprenavir calcium salt. Group: Biochemicals. Alternative Names: GW-433908G; Lexiva; Telzir. Grades: Highly Purified. CAS No. 226700-81-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C25H34CaN3O9PS. US Biological Life Sciences. | Worldwide |
| Fosamprenavir Calcium Salt | HIV protease inhibitor; water soluble prodrug of amprenavir. Synonyms: GW 433908G; Lexiva; GW433908G; GW-433908G. Grades: >98%. CAS No. 226700-81-8. Molecular formula: C25H34CaN3O9PS. Mole weight: 623.67. | |
| Fosamprenavir Calcium Salt (GW-433908G, Lexiva, Telzir) | HIV protease inhibitor; water soluble prodrug of amprenavir. Group: Biochemicals. Alternative Names: GW-433908G; Lexiva; Telzir. Grades: Highly Purified. CAS No. 226700-81-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Fosamprenavir-d4 Calcium Salt (GW-433908G-d4, Lexiva-d4, Telzir-d4) | HIV protease inhibitor; water soluble prodrug of amprenavir. Group: Biochemicals. Alternative Names: GW-433908G-d4; Lexiva-d4; Telzir-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Fosamprenavir enantiomer | Grades: > 95%. Molecular formula: C25H36N3O9PS. Mole weight: 585.62. | |
| Fosamprenavir Related Compound | Grades: > 95%. Molecular formula: C20H30N3O6PS. Mole weight: 471.52. | |
| Fosaprepitant | Fosaprepitant is a selective neurokinin-1 (NK-1) receptor antahonist. It is an antiemetic drug, which is a Aprepitant prodrug. Uses: Antiemetics. Synonyms: P-[3-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonic Acid; L 758298; [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)mor. Grades: > 95%. CAS No. 172673-20-0. Molecular formula: C23H22F7N4O6P. Mole weight: 614.42. | |
| Fosaprepitant | Fosaprepitant (L-785298) is a proagent of Aprepitant (HY-10052). Fosaprepitant is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L-758298. CAS No. 172673-20-0. Pack Sizes: 1 mg. Product ID: HY-14407. | |
| Fosaprepitant Benzyl Ester | Cas No. 889852-02-2. | |
| Fosaprepitant Dibenzyl Ester | Fosaprepitant Dibenzyl Ester is a reactant in the synthesis of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(Trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]-phosphonic Acid bis(Phenylmethyl) Ester; Dibenzyl Fosaprepitant; Fosaprepitant Impurity 16; Phosphonic acid, P-[3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]-, bis(phenylmethyl) ester; 2-Bis(phenylmethoxy)phosphoryl-5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-4H-1,2,4-triazol-3-one. Grades: >95%. CAS No. 265121-01-5. Molecular formula: C37H34F7N4O6P. Mole weight: 794.65. | |
| Fosaprepitant dimeglumine | Fosaprepitant dimeglumine (MK-0517) is a proagent of Aprepitant (HY-10052). Fosaprepitant dimeglumine is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-0517; L785298. CAS No. 265121-04-8. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14407A. | |
| Fosaprepitant Dimeglumine | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopychiral molecules. Alternative Names: D-Glucitol, 1-deoxy-1-(methylamino)-, [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate (2:1) (salt) (9CI), Fosaprepitant di(N-methylglucamine), Phosphonic acid, [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]-, compd. with 1-deoxy-1-(methylamino)-D-glucitol (1:2) (9CI),D-Glucitol, 1-deoxy-1-(methylamino)-, [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate (2:1), Fosaprepitant dimeglumine, MK 0517. | |
| Fosaprepitant Dimeglumine | Fosaprepitant is a selective neurokinin-1 (NK-1) receptor antahonist. Fosaprepitant is an antiemetic drug, a Aprepitant prodrug. Group: Biochemicals. Alternative Names: [3-[[ (2R, 3S) -2-[ (1R) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]-3- (4-fluorophenyl) -4-morpholinyl]methyl]-2, 5-dihydro-5-oxo-1H-1, 2, 4-triazol-1-yl]phosphonate 1-Deoxy-1-(methylamino)-D-glucitol; MK 0517. Grades: Highly Purified. CAS No. 265121-04-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Fosaprepitant Impurity 1 | A metabolite of Aprepitant. Synonyms: [2R-[2α(S*),3α]]-5-[[2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-Triazol-3-one. Grades: > 95%. CAS No. 170902-81-5. Molecular formula: C23H21F7N4O3. Mole weight: 534.44. | |
| Fosaprepitant Impurity 2 | A metabolite of Aprepitant. Synonyms: [2R-[2α(R*),3α]]-5-[[2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-oxido-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one. Grades: > 95%. CAS No. 172673-23-3. Molecular formula: C23H21F7N4O4. Mole weight: 550.44. | |
| Fosaprepitant Impurity 3 | A metabolite of Aprepitant. Synonyms: (2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-4-(phenylmethyl)-3-morpholinone. Grades: > 95%. CAS No. 287930-75-0. Molecular formula: C21H19F6NO3. Mole weight: 447.38. | |
| Fosaprepitant Morpholine | Fosaprepitant Morpholine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: Fosaprepitant Impurity 27; Morpholine, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-, (2S,3S)-; Aprepitant M2 Metabolite (1R,2S,3S)-Isomer; Aprepitant impurity 20; (2S,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine. Grades: ≥95%. CAS No. 170902-80-4. Molecular formula: C20H18F7NO2. Mole weight: 437.35. | |
| Fosaprepitant N-Benzyl Impurity | Grades: > 95%. Molecular formula: C30H28F7N4O6P. Mole weight: 704.54. | |
| Fosaprepitant N-oxide | Fosaprepitant N-oxide is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (3-{[(2R,3S)-2-{(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}-3-(4-fluorophenyl)-4-oxido-4-morpholinyl]methyl}-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid; Phosphonic acid, [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-oxido-4-morpholinyl]methyl]-4,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]-. Molecular formula: C23H22F7N4O7P. Mole weight: 630.41. | |
| Fosbretabulin | Fosbretabulin, also called as CA4P, has antitumor activity against anaplastic thyroid cancer (ATC) cell lines. Fosbretabulin, a novel water-soluble vascular-disrupting agent, is a phosphate derivative of a natural stilbenoid phenol derived from the African bush willow (Combretum caffrum). Synonyms: [2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] dihydrogen phosphate; 3,4,5-trimethoxy-3'-hydroxy-4'-methoxystilbene; CA4DP; combretastatin A-4; 168555-66-6 (fosbretabulin disodium); 82855-09-2 (combretastatin); 117048 -59-6 (combretastatin A4). Grades: >98%. CAS No. 222030-63-9. Molecular formula: C18H21O8P. Mole weight: 396.33. | |
| Fosbretabulin disodium | Fosbretabulin disodium is the disodium salt of a water-soluble phosphate derivative of a natural stilbenoid phenol derived from the African bush willow (Combretum caffrum) with potential vascular disrupting and antineoplastic activities. Upon administration, the prodrug fosbretabulin is dephosphorylated to its active metabolite, the microtubule-depolymerizing agent combretastatin A4, which binds to tubulin dimers and prevents microtubule polymerization, resulting in mitotic arrest and apoptosis in endothelial cells. In addition, this agent disrupts the engagement of the endothelial cell-specific junctional molecule vascular endothelial-cadherin (VE-cadherin) and so the activity of the VE-cadherin/β-catenin/Akt signaling pathway, which may result in the inhibition of endothelial cell migration and capillary tube formation. As a result of fosbretabulin's dual mechanism of action, the tumor vasculature collapses, resulting in reduced tumor blood flow and ischemic necrosis of tumor tissue. Synonyms: Combretastatin A-4 phosphate disodium, CA4P; CA4DP; Combretastatin A-4 phosphate. CAS No. 168555-66-6. Molecular formula: C18H19Na2O8P. Mole weight: 440.295. | |
| Fosbretabulin disodium | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Foscarbidopa | Foscarbidopa (ABBV-951; Carbidopa 4-monophosphate) is a proagent of Carbidopa, acts as a dopamine receptor agonist [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABBV-951; Carbidopa 4-monophosphate. CAS No. 1907685-81-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109131. | |
| Foscarnet | Foscarnet is a pyrophosphate analog DNA polymerase inhibitor that has activity against several viruses, but is primarily used to treat CMV retinitis. Because it can cross the blood-brain barrier, it can be used to treat viral infections of the central nervous system. Synonyms: Phosphonoformate; Carboxyphosphonic acid; Foscarmet; Phosphonocarboxylic acid; Dihydroxyphosphinecarboxylic acid oxide; Phosphonomethanoic acid; Dihydroxyphosphanecarboxylic acid oxide; Phgosphonocarboxylic acid; NSC313410; Phosphinecarboxylic acid, 1,1-dihydroxy-, 1-oxide; Foscamet. Grades: 95%. CAS No. 4428-95-9. Molecular formula: CH3O5P. Mole weight: 126.01. | |
| Foscarnet Related Compound B | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Foscarnet Related Compound D | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Foscarnet sodium | Foscarnet sodium (Trisodium phosphonoformate) is a viral DNA polymerase activity inhibitor, leading to reversible suppression of viral replication. Foscarnet sodium is an antiherpesvirus agent used in cytomegalovirus retinitis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Trisodium phosphonoformate; Phosphonoformic acid trisodium salt. CAS No. 63585-09-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1318. | |
| Foscarnet sodium | Foscarnet Sodium inhibits viral RNA polymerases, reverse transcriptases and DNA polymerases by non-competitive inhibition of dNTPs. It is an antiviral agent used in the treatment of cytomegalovirus retinitis. It has activity against human herpesviruses and HIV. Uses: Antiviral agents. Synonyms: Trisodium phosphonoformate; Trisodium carboxyphosphate; Foscarnet trisodium; Phosphonoformic acid trisodium salt; 1,1-Dihydroxyphosphinecarboxylic Acid 1-Oxide Sodium Salt; A 29622; EHB 776; Gefin; Triapten. Grades: >98%. CAS No. 63585-09-1. Molecular formula: CNa3O5P. Mole weight: 191.95. | |
| Foscarnet sodium | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Foscarnet sodium | Foscarnet sodium. Group: Biochemicals. Alternative Names: 1, 1-Di hydroxyphosphinecar boxyl ic acid 1-oxide sodium salt; A 29622; EHB 776. Grades: Highly Purified. CAS No. 63585-09-1. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: CNa3O5P. US Biological Life Sciences. | Worldwide |
| Foscarnet Sodium | Pharmaceutical Secondary Standard; Certified Reference Material. Group: Pharmacopeia & metrological institutes standards. | |
| Foscarnet Sodium Hexahydrate | Foscarnet Sodium Hexahydrate is an antiviral drug used in the treatment of cytomegalovirus retinitis. It has inhibitory effect on viral DNA polymerase and reverse transcriptase. Synonyms: Sodium phosphonoformate tribasic hexahydrate; 1,1-Dihydroxyphosphinecarboxylic Acid 1-Oxide Sodium Salt Hydrate; A 29622 Hydrate; EHB 776 Hydrate; Foscavir Hydrate; Gefin Hydrate; PFA Hydrate; Phosphonoformic Acid Trisodium Salt Hydrate; Triapten Hexahydrate; Trisodium Phosphonoformate Hexahydrate. Grades: 95%. CAS No. 34156-56-4. Molecular formula: CH12Na3O11P. Mole weight: 300.04. | |
| Fos-choline -13,sol-grade | Fos-choline -13,sol-grade. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FOS-CHOLINE?-13, SOL-GRADE?. Product Category: Heterocyclic Organic Compound. CAS No. 85775-42-4. Molecular formula: C18H40NO4P. Mole weight: 365.491. Product ID: ACM85775424. Alfa Chemistry ISO 9001:2015 Certified. | |
| Fosciclopirox | Fosciclopirox suppresses growth of urothelial cancer by targeting the γ-secretase complex. Fosciclopirox selectively delivers the active metabolite, Ciclopirox (CPX), to the entire urinary tract [1] [2]. Ciclopirox has anticancer activity in a number of solid and hematologic malignancies. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CPX-POM. CAS No. 1380539-06-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109174. | |
| Fosdagrocorat | Fosdagrocorat (PF-04171327) is a dissociated glucocorticoid receptor agonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-04171327. CAS No. 1044535-58-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16722. | |
| Fosdevirine | Fosdevirine is a highly potent next-generation Anti-HIV nonnucleoside reverse transcriptase inhibitor (NNRTI) with an EC50 of 11 nM. It is a novel and once-daily (QD) inhibitor with activity against efavirenz-resistant strains. It demonstrated potent antiviral activity in treatment-naive HIV-infected subjects, and had favorable PK and resistance profiles. It was originally developed by idenix pharmaceuticals and was in clinical phase 2, but now it has been terminated. Uses: Fosdevirine has potent antiviral activity. Synonyms: GSK2248761; GSK-2248761; GSK 2248761; GSK2248761A; GSK-2248761A; GSK 2248761A; IDX899; IDX-899; IDX 899, Fosdevirine;Methyl (E)-(2-carbamoyl-5-chloro-1H-indol-3-yl)(3-(2-cyanovinyl)-5-methylphenyl)phosphinate;5-Chloro-3-[[3-[(E)-2-cyanoethenyl]-5-methylphenyl]-methoxyphosphoryl]-1H-indole-2-carboxamide. Grades: 95%. CAS No. 1018450-26-4. Molecular formula: C20H17ClN3O3P. Mole weight: 413.80. | |
| Fosfadecin | Fosfadecin is produced by the strain of Pseudomonas fluorescens PK-5. It has a weak antibacterial activity, the ED50 of Escherichia coli O-111 and Staphylococcus aureus 308A-1 was 800mg/kg and 566mg/kg (mice, oral). Synonyms: Tan 930; 9-[5-O- (Hydroxy{[hydroxy (3-methyloxiran-2-yl) phosphoryl]oxy}phosphoryl) pentofuranosyl]-9H-purin-6-amine. CAS No. 120909-50-4. Molecular formula: C13H19N5O10P2. Mole weight: 467.27. | |
| Fosfazinomycin A | Fosfazinomycin A is produced by the strain of Streptomyces lavendofoliae. It has the activity of resisting plant pathogenic fungi such as Xanthomonas oryzae. Molecular formula: C15H32N7O7P. Mole weight: 453.43. | |
| Fosfazinomycin B | Fosfazinomycin B is produced by the strain of Streptomyces lavendofoliae. It has the activity of resisting plant pathogenic fungi such as Xanthomonas oryzae. Synonyms: L-Arginine 2-[hydroxy(1-hydroxy-2-methoxy-2-oxoethyl)phosphinyl]-2-methyl hydrazide. CAS No. 87423-11-8. Molecular formula: C10H23N6O6P. Mole weight: 354.30. | |
| Fosfenopril | Fosfenopril (Fosinoprilat) is a potent angiotensin converting enzyme ( ACE ) inhibitor. Fosfenopril alleviates lipopolysaccharide (LPS)-induced inflammation by inhibiting TLR4/NF-κB signaling in monocytes [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Fosinoprilat; Fosinoprilic acid; SQ 27519. CAS No. 95399-71-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-107352. | |
| Fosfestrol Tetrasodium Salt | Fosfestrol is an estrogen medication used in the treatment of prostate cancer in men. Synonyms: sodium (E)-hex-3-ene-3,4-diylbis(4,1-phenylene) bis(phosphate); 4,4'-Dihydroxy-alpha,alpha'-diethyl-stilben-diphosphate tetrasodium; Diethylstilbestrol 4,4'-di(disodium phosphate); Diethylstilbestrol diphosphate tetrasodium salt; Honvol; ST 52-Asta; Sodium diethylstilbesterol diphosphate; Stilbestrol diphosphate sodium; Stilbostatin; Tetrasodium fosfestrol. Grades: 98%. CAS No. 4719-75-9. Molecular formula: C18H18Na4O8P2. Mole weight: 516.24. | |
| Fosfluconazole | Fluconazole, a water-soluble phosphate prodrug of fluconazole, is a triazole antifungal agent that is effective against most Candida strains. Uses: 14-alpha demethylase inhibitors. Synonyms: Procif; UK 292663; UK-292,663. Grades: > 95%. CAS No. 194798-83-9. Molecular formula: C13H13F2N6O4P. Mole weight: 386.26. | |
| Fosfluconazole | Fosfluconazole. Group: Biochemicals. Alternative Names: 2-(2,4-Difluorophenyl)-1,3-di(1H-1,2,4-triazol-1-yl)propyl dihydrogen phosphate. Grades: Highly Purified. CAS No. 194798-83-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C13H13F2N6O4P. US Biological Life Sciences. | Worldwide |
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