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This pseudoproline dipeptide is undoubtedly the most effective and simplest to use tool for overcoming aggregation and enhancing peptide quality in Fmoc SPPS for peptide containing the Trp-Ser dipeptide motif. It consists of a dipeptide in which the serine residue has been reversibly protected as a structure-breaking proline-like TFA-labile oxazolidine. The reason the pseudoproline residue is introduced as a dipeptide is because it avoids the need to acylate the hindered oxazolidine nitrogen. This has the added advantage of extending the peptide chain by two residues in one step. The serine residue is regenerated during the normal TFA-mediated cleavage reaction. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Trp(Boc)-Ser(psiMe,Mepro)-OH. CAS No. 908601-15-0. Mole weight: 653.72. Catalog: ACM908601150.
This pseudoproline dipeptide is undoubtedly the most effective and simplest to use tool for overcoming aggregation and enhancing peptide quality in Fmoc SPPS for peptide containing the Trp-Thr dipeptide motif. It consists of a dipeptide in which the threonine residue has been reversibly protected as a structure-breaking proline-like TFA-labile oxazolidine. The reason the pseudoproline residue is introduced as a dipeptide is because it avoids the need to acylate the hindered oxazolidine nitrogen. This has the added advantage of extending the peptide chain by two residues in one step. The threonine residue is regenerated during the normal TFA-mediated cleavage reaction. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Trp(Boc)-Thr(psiMe,Mepro)-OH. CAS No. 936707-21-0. Mole weight: 667.75. Catalog: ACM936707210.
Building block for introduction of typtophan by Fmoc SPPS. Superceded by Fmoc-Trp(Boc)-OH. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Trp-OH, N-α-Fmoc-L-tryptophan. CAS No. 35737-15-6. Mole weight: 426.46. Catalog: ACM35737156.
Heterocyclic Organic Compound. Alternative Names: FMOC-O-BENZYL-L-TYROSYL CHLORIDE;FMOC-TYR(BZL)-CL;NALPHA-9-Fluorenylmethoxycarbonyl-O-benzyl-L-tyrosyl chloride. CAS No. 103321-60-4. Molecular formula: C31H26ClNO4. Mole weight: 512. Catalog: ACM103321604.
Fmoc-Tyr(Me)-OH
Standard building block for introduction of O-methyl-tyrosine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Tyr(Me)-OH, N-α-Fmoc-O-methyl-L-tyrosine. CAS No. 77128-72-4. Molecular formula: C25H23NO5. Mole weight: 417.45. Catalog: ACM77128724.
Fmoc-Tyr(Me)-OH
Fmoc-Tyr(Me)-OH is a tyrosine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 77128-72-4. Pack Sizes: 10 g; 25 g; 100 g. Product ID: HY-W010943.
Fmoc-Tyr-OH
Fmoc-Tyr-OH. Group: Biochemicals. Alternative Names: N-Fmoc-L-tyrosine. Grades: Highly Purified. CAS No. 92954-90-0. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C24H21NO5. US Biological Life Sciences.
Worldwide
Fmoc-Tyr-OH
Fmoc-Tyr-OH is a tyrosine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 92954-90-0. Pack Sizes: 25 g; 100 g. Product ID: HY-W009003.
Fmoc-Tyr-OH
A useful derivative for the synthesis of phosphotyrosine peptides by the global Fmoc SPPS phosphorylation methodology. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Tyr-OH, N-α-Fmoc-L-tyrosine. CAS No. 92954-90-0. Molecular formula: C24H21NO5. Mole weight: 403.43. Catalog: ACM92954900.
A novel derivative for the synthesis of sulfotyrosine-containing peptides by Fmoc SPPS. The sulfate neopentyl group is stable to TFA, and thus protects the sulfotyrosine residue from degradation during the cleavage reaction, but is easily cleaved post-cleavage by treatment of the peptide with aqueous ammonium acetate. Group: Biochemicals. Grades: Highly Purified. CAS No. 878408-63-0. Pack Sizes: 1g. Molecular Formula: C??H??NO?S, Enantiomeric. US Biological Life Sciences.
Worldwide
Fmoc-Tyr(SO3nP)-OH
A novel derivative for the synthesis of sulfotyrosine-containing peptides by Fmoc SPPS. The sulfate neopentyl group is stable to TFA, and thus protects the sulfotyrosine residue from degradation during the cleavage reaction, but is easily cleaved post-cleavage by treatment of the peptide with aqueous ammonium acetate. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Tyr(SO3nP)-OH, N-Fmoc-O-(2,2 dimethylpropylsulfo)-L-tyrosine. CAS No. 878408-63-0. Molecular formula: C29H31NO8S. Mole weight: 553.62. IUPACName: (2S)-3-[4- (2, 2-dimethylpropoxysulfonyloxy)phenyl]-2- (9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid. Canonical SMILES: CC (C) (C)COS (=O) (=O)OC1=CC=C (C=C1)CC (C (=O)O)NC (=O)OCC2C3=CC=CC=C3C4=CC=CC=C24. Catalog: ACM878408630.
Fmoc-Tyr(tBu)-OH is a tyrosine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 71989-38-3. Pack Sizes: 25 g; 100 g; 500 g. Product ID: HY-W008016.
Fmoc-Tyr(tBu)-OH
High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Standard building block for introduction of tyrosine amino-acid residues by Fmoc SPPS. Uses: Fmoc-tyr(tbu)-oh novabiochem®. cas 71989-38-3, molar mass 459.55 g/mol. Group: Amino acids. Alternative Names: Fmoc-Tyr(tBu)-OH, N-α-Fmoc-O-t.-butyl-L-tyrosine. CAS No. 71989-38-3. Molecular formula: C28H29NO5. Mole weight: 459.53. Purity: Peak Area by HPLC ≥95%. Catalog: ACM71989383.
Fmoc-Tyr(tBu)-OH
Fmoc-Tyr(tBu)-OH. Group: Biochemicals. Grades: Highly Purified. CAS No. 71989-38-3. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C28H29NO5. US Biological Life Sciences.
This pseudoproline dipeptide is undoubtedly the most effective and simplest to use tool for overcoming aggregation and enhancing peptide quality in Fmoc SPPS for peptide containing the Tyr-Ser dipeptide motif. It consists of a dipeptide in which the serine residue has been reversibly protected as a structure-breaking proline-like TFA-labile oxazolidine. The reason the pseudoproline residue is introduced as a dipeptide is because it avoids the need to acylate the hindered oxazolidine nitrogen. This has the added advantage of extending the peptide chain by two residues in one step. The serine residue is regenerated during the normal TFA-mediated cleavage reaction. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Tyr(tBu)-Ser(psiMe,Mepro)-OH. CAS No. 878797-09-2. Mole weight: 586.67. Catalog: ACM878797092.
Fmoc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1394238-92-6. Pack Sizes: 100 mg; 250 mg. Product ID: HY-136136.
Fmoc-Val-Cit-PAB is a linked conjugate for ADC. Synonyms: Fmoc-Val-Cit-PAB-OH. CAS No. 159858-22-7. Molecular formula: C33H39N5O6. Mole weight: 601.704.
Fmoc-Val-Cit-PAB-PNP
A useful protective group in antibody drug conjugates. Synonyms: N-[ (9H-Fluoren-9-ylmethoxy) carbonyl]-L-valyl-N5-carbamoyl-N-[4- ({[ (4-nitrophenoxy) carbonyl]oxy}methyl) phenyl]-L-ornithinamide. Grades: ≥98%. CAS No. 863971-53-3. Molecular formula: C40H42N6O10. Mole weight: 766.79.
Fmoc-Val-OH. Group: Biochemicals. Alternative Names: N- (9-Fluorenyl methoxycarbonyl ) -L-valine. Grades: Highly Purified. CAS No. 68858-20-8. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. Molecular Formula: C20H21NO4. US Biological Life Sciences.
Worldwide
Fmoc-Val-OH
High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Standard building block for introduction of valine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Val-OH, N-α-Fmoc-L-valine. CAS No. 68858-20-8. Molecular formula: C20H21NO4. Mole weight: 339.39. Catalog: ACM68858208.
FMOC-VAL-OH
FMOC-VAL-OH. CAS No: 68858-20-8
Sarchem Laboratories New Jersey NJ
Fmoc-Val-OH-[15N]
Synonyms: N-(9-Fluorenylmethoxycarbonyl)-L-valine-15N; Fmoc-Val-OH-15N. Grades: 99% by CP; 98% atom 15N. CAS No. 125700-35-8. Molecular formula: C20H21[15N]O4. Mole weight: 340.38.