A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Hibarimicin A is a tyrosine kinase inhibitor produced by Microbispora rosea subsp. hibaria. It selectively inhibits the activity of src tyrosine kinase without affecting protein kinase A and C. It also has moderate anti-Gram-positive bacteria activity with a MIC of 0.8-12.56 μg/mL. Molecular formula: C85H112O37. Mole weight: 1725.77.
Hibarimicin B
Hibarimicin B is a tyrosine kinase inhibitor produced by Microbispora rosea subsp. hibaria. It selectively inhibits the activity of src tyrosine kinase without affecting protein kinase A and C. It also has moderate anti-Gram-positive bacteria activity with a MIC of 0.8-12.56 μg/mL. Molecular formula: C85H112O37. Mole weight: 1725.77.
Hibarimicin C
Hibarimicin C is a tyrosine kinase inhibitor produced by Microbispora rosea subsp. hibaria. It selectively inhibits the activity of src tyrosine kinase without affecting protein kinase A and C. It also has moderate anti-Gram-positive bacteria activity with a MIC of 0.8-12.56 μg/mL. Molecular formula: C83H110O36. Mole weight: 1683.74.
Hibarimicin D
Hibarimicin D is a tyrosine kinase inhibitor produced by Microbispora rosea subsp. hibaria. It selectively inhibits the activity of src tyrosine kinase without affecting protein kinase A and C. It also has moderate anti-Gram-positive bacteria activity with a MIC of 0.8-12.56 μg/mL. CAS No. 208588-87-8. Molecular formula: C85H112O38. Mole weight: 1741.77.
Hibarimicin E
Hibarimicin E is a tyrosine kinase inhibitor produced by Microbispora rosea subsp. hibaria. Molecular formula: C77H100O34. Mole weight: 1569.59.
Hibarimicin G
Hibarimicin G is a tyrosine kinase inhibitor produced by Microbispora rosea subsp. hibaria. Molecular formula: C85H112O39. Mole weight: 1757.77.
Hibarimicin H
Hibarimicin H is a tyrosine kinase inhibitor produced by Microbispora rosea subsp. hibaria. Molecular formula: C75H98O33. Mole weight: 1527.56.
Hibarimicinone
Hibarimicinone is a tyrosine kinase inhibitor produced by Microbispora rosea subsp. hibaria. Molecular formula: C45H48O21. Mole weight: 924.85.
Hibifolin
Hibifolin is a flavonol glycoside that prevents beta-amyloid-induced neurotoxicity in vitro. Hibifolin prevents beta-amyloid-induced neurotoxicity in cultured cortical neurons. Hibifolin is a potential inhibitor of adenosine deaminase. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Hibifolin; Gossypetin 8-O-beta-D-glucuronide. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 55366-56-8. Molecular formula: C21H18O14. Mole weight: 494.36. Purity: 0.99. IUPACName: beta-D-Glucopyranosiduronic acid, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4-oxo-4H-1-benzopyran-8-yl. Canonical SMILES: O[C@H]([C@H]([C@@H]([C@@H](C(O)=O)O1)O)O)[C@@H]1OC2=C3C(C(C(O)=C(C4=CC=C(O)C(O)=C4)O3)=O)=C(O)C=C2O. Product ID: ACM55366568. Alfa Chemistry ISO 9001:2015 Certified.
Hibifolin
Hibifolin is a biomedical compound, aiding in research of inflammation-induced afflictions, including the pervasive rheumatoid arthritand pernicious dermatitis. Synonyms: [2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4-oxo-4H-1-benzopyran-8-yl]b-D-glucopyranosiduronic acid. CAS No. 55366-56-8. Molecular formula: C21H18O14. Mole weight: 494.36.
Hibiscus Flower Extract (Standard)
Hibiscus grows in tropical grows in tropical areas throughout the world, and has been used not just as an ornament, but also medicinally for centuries. The part of this plant used medicinally is the flower. The Hibiscus flower is made into a tea in numerous cultures throughout the world. Hibiscus has a mild flavor and has many culinary uses. Applications: Hibiscus extract was used by the chinese to treat dandruff and stimulate hair growthhibiscus extract has also been used to treat hemorrhoids and woundsrecent research has shown that hibiscus extract may have antibacterial properties. Group: Others. Purity: 5.0% Anthocyanins UV. Mole weight: 207.24. Hibiscus Flower Extract (Standard); C15H11O. Cat No: EXTW-017.
HiCel 12 (MCC 12)
HiCel 12 (MCC 12). Coarse particle size, spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, combines good flow and high binding capacity. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for pharmaceutical applications. Dosage Form: Capsule, Powder, Tablet. Functionality: Binder, Carrier, Capsule Filling, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility. Process: Capsule Filling, Direct Compression, Dry Granulation. Particle Size: 150 microns.
Sigachi US Inc
HiCel 14 (Low Moisture MCC 12)
HiCel 14 (Low Moisture MCC 12). Extra low moisture (<1.5%), coarse particle size, spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose for processing moisture-sensitive active ingredients. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for pharmaceutical applications. Dosage Form: Capsule, Powder, Tablet. Functionality: Binder, Carrier, Capsule Filling, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Moisture-Sensitive Active Ingredient, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility. Process: Capsule Filling, Direct Compression, Dry Granulation. Particle Size: 150 microns.
Sigachi US Inc
HiCel 25M (MCC 105)
HiCel 25M (MCC 105). Extra fine particle size, spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, has a smooth texture and mouthfeel. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for pharmaceutical applications. Dosage Form: Capsule, Multiple Dosage Forms, Orally Disintegrating Tablet, Semi-Solid, Tablet, Topical. Functionality: Binder, Capsule Filling, Carrier, Compaction, Diluent, Filler, Granulation, Multifunctional, Natural Origin, Tablet Compressibility, Wet Granulation. Process: Capsule Filling, Extrusion, Roller Compaction, Wet Granulation. Particle Size: 25 microns.
Sigachi US Inc
HiCel 50M (MCC 101)
HiCel 50M (MCC 101). Fine particle size, spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, highly compressible. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for pharmaceutical applications. Dosage Form: Tablet. Functionality: Binder, Carrier, Compaction, Diluent, Filler, Granulation, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility, Wet Granulation. Process: Extrusion, Roller Compaction, Spheronization, Wet Granulation. Particle Size: 50 microns.
Sigachi US Inc
HiCel 90M (MCC 102)
HiCel 90M (MCC 102). Medium particle size, spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, combines flow and high compactibility. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for pharmaceutical applications. Dosage Form: Capsule, Powder, Tablet. Functionality: Binder, Carrier, Capsule Filling, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility. Process: Capsule Filling, Direct Compression, Dry Granulation. Particle Size: 90 microns.
Sigachi US Inc
HiCel HD50M (High BD MCC 101)
HiCel HD50M (High BD MCC 101). Fine particle size, high density, spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, combines good flow and less volume. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for pharmaceutical applications. Dosage Form: Capsule. Functionality: Capsule Filling, Carrier, Diluent, Filler, Natural Origin. Process: Capsule Filling. Particle Size: 50 microns.
Sigachi US Inc
HiCel HD90M (High BD MCC 102)
HiCel HD90M (High BD MCC 102). High density, medium particle size, spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, combines high flow and excellent binding property. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for pharmaceutical applications. Dosage Form: Capsule, Powder, Tablet. Functionality: Capsule Filling, Binder, Carrier, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Multifunctional, Powder Blends, Natural Origin, Tablet Compressibility. Process: Capsule Filling, Direct Compression, Dry Granulation. Particle Size: 90 microns.
Sigachi US Inc
HiCel LM50 (Low moisture MCC 101)
HiCel LM50 (Low moisture MCC 101). Extra low moisture (<1.5%), fine particle size, spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, for processing moisture-sensitive active ingredients. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for pharmaceutical applications. Dosage Form: Capsule. Functionality: Binder, Capsule Filling, Carrier, Compaction, Diluent, Filler, Moisture-Sensitive Active Ingredient, Natural Origin, Tablet Compressibility. Process: Capsule Filling, Extrusion, Roller Compaction, Spheronization. Particle Size: 50 microns.
Sigachi US Inc
HiCel LP200 (MCC 200)
HiCel LP200 (MCC 200). Large particle size, spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, combines outstanding flow and high binding capacity. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for pharmaceutical applications. Dosage Form: Capsule, Powder, Tablet. Functionality: Binder, Carrier, Capsule Filling, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility. Process: Capsule Filling, Direct Compression, Dry Granulation. Particle Size: 180 microns.
Sigachi US Inc
HiCel MCG 581 (Cellulose Gel)
HiCel MCG 581 (Cellulose Gel). Microcrystalline Cellulose co-processed with Sodium Carboxymethyl Cellulose is a highly thixotropic hydrocolloid. It is a white, odorless, and tasteless powder that produces and stabilizes one-phase suspension, smooth cream, gel, and lotion. Dosage Form: Cream, Gel, Lotion, Suspension, Topical. Functionality: Smooth Texture, Stabilizer, Suspending Agent, Viscosity Modifier. Process: Emulsion Stabilization, Suspension Stabilization, Viscosity Modification. Particle Size: 70 microns.
Sigachi US Inc
HiCel MCG 591 (Cellulose Gel)
HiCel MCG 591 (Cellulose Gel). Microcrystalline Cellulose co-processed with Sodium Carboxymethyl Cellulose resulting in a highly thixotropic hydrocolloid. It is a white, odorless, and tasteless powder that is activated by high-shear mixer to produce stable, one-phase suspension, smooth cream, gel, and lotion. Dosage Form: Cream, Gel, Lotion, Suspension, Topical. Functionality: Smooth Texture, Stabilizer, Suspending Agent, Viscosity Modifier. Process: Emulsion Stabilization, Suspension Stabilization, Viscosity Modification. Particle Size: 70 microns.
Sigachi US Inc
HiCel MCG 611 (Cellulose Gel)
HiCel MCG 611 (Cellulose Gel). Microcrystalline Cellulose co-processed with Sodium Carboxymethyl Cellulose resulting in a highly thixotropic hydrocolloid. It is a white, odorless, and tasteless powder that is activated by high-shear mixer to produce stable, one-phase suspension, smooth cream, gel, and lotion. Dosage Form: Cream, Gel, Lotion, Suspension, Topical. Functionality: Smooth Texture, Stabilizer, Suspending Agent, Viscosity Modifier. Process: Emulsion Stabilization, Suspension Stabilization, Viscosity Modification. Particle Size: 70 microns.
Sigachi US Inc
HiCel SMCC 50M (SMCC 101)
HiCel SMCC 50M (SMCC 101). Fine particle size, microcrystalline Cellulose co-processed with Silicon Dioxide results in a free-flowing powder. It is an excellent aid that improves significantly the flow in capsule filling and tableting. Dosage Form: Capsule, Powder, Tablet. Functionality: Binder, Carrier, Capsule Filling, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility. Process: Capsule Filling, Direct Compression, Dry Granulation. Particle Size: 50 microns.
Sigachi US Inc
HiCel SMCC 90M (SMCC 102)
HiCel SMCC 90M (SMCC 102). Medium particle size, microcrystalline Cellulose co-processed with Silicon Dioxide results in a free-flowing powder. It is an excellent aid that improves significantly the flow in capsule filling and tableting. Dosage Form: Capsule, Powder, Tablet. Functionality: Binder, Carrier, Capsule Filling, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility. Process: Capsule Filling, Direct Compression, Dry Granulation. Particle Size: 90 microns.
Sigachi US Inc
HiCel SMCC HD 90M (SMCC 102)
HiCel SMCC HD 90M (SMCC 102). High density, medium particle size, microcrystalline Cellulose co-processed with Silicon Dioxide results in a free-flowing powder. It is an excellent aid that improves significantly the flow in capsule filling and tableting, resulting in less volume. Dosage Form: Capsule, Powder, Tablet. Functionality: Binder, Carrier, Capsule Filling, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility. Process: Capsule Filling, Direct Compression, Dry Granulation. Particle Size: 90 microns.
Sigachi US Inc
HiCel SMCC LM 90M (SMCC 102)
HiCel SMCC LM 90M (SMCC 102). Low moisture (<1.5%), medium particle size, microcrystalline Cellulose co-processed with Silicon Dioxide results in a free-flowing powder. It is an excellent aid that improves significantly the flow in capsule filling and tableting, for processing moisture-sensitive active ingredients. Dosage Form: Capsule, Powder, Tablet. Functionality: Binder, Carrier, Capsule Filling, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Moisture-Sensitive Active Ingredient, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility. Process: Capsule Filling, Direct Compression, Dry Granulation. Particle Size: 90 microns.
Sigachi US Inc
HiCelTM CE15
HiCelTM CE15. HiCelTM CE15 is a co-processed composed of microcrystalline cellulose and guar gum. Its free-flowing characteristic allows the production of chewable tablets that pleases end-users mouthfeel, primarily in the areas of overall sensory experience, such as the perception of taste when compared to other excipients. Dosage Form: Chewable Tablet. Functionality: Binder, Smooth Texture, Mouthfeel. Process: Direct Compression, Dry Granulation, Wet Granulation. Particle Size: 45 Microns.
Sigachi US Inc
HiCel XLM 200 (Low moisture MCC 200)
HiCel XLM 200 (Low moisture MCC 200). Extra low moisture (<1.5%), high density, large particle size spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, combines outstanding flow and excellent binding property for processing moisture-sensitive active ingredients. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for pharmaceutical applications. Dosage Form: Capsule, Powder, Tablet. Functionality: Binder, Capsule Filling, Carrier, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Moisture-Sensitive Active Ingredient, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility. Process: Direct Compression, Dry Granulation. Particle Size: 180 microns.
Sigachi US Inc
HiCel XLM 90 (Low moisture MCC 102)
HiCel XLM 90 (Low moisture MCC 102). Extra low moisture (<1.5%), high density, medium particle size spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, combines outstanding flow and good binding property for processing moisture-sensitive active ingredients. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for pharmaceutical applications. Dosage Form: Capsule, Powder, Tablet. Functionality: Binder, Capsule Filling, Carrier, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Moisture-Sensitive Active Ingredient, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility. Process: Capsule Filling, Direct Compression, Dry Granulation. Particle Size: 90 microns.
Sigachi US Inc
HIDC iodide
HIDC iodide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3,3-trimethyl-nyl]-iodide;3h-indolium,2-[5-(1,3-dihydro-1,3,3-trimethyl-2h-indol-2-ylidene)-1,3-pentadie;1,1',3,3,3',3'-HEXAMETHYLINDODICARBOCYANINE IODIDE;1,1,3,3,3',3'-HEXAMETHYLINDODICARBOCYANINE IODIDE;DIIC1(5);HIDC IODIDE;2-[5-(1,3-dihydro-1,3,3-tri. Product Category: Photonic and Optical Device. CAS No. 36536-22-8. Molecular formula: C27H31IN2. Mole weight: 510.45. Product ID: ACM36536228. Alfa Chemistry ISO 9001:2015 Certified.
HIDC iodide
HIDC iodide is a carbocyanine dye that stains mitochondria of live cells. Synonyms: DiIC1(5); 2-[5-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1,3-pentadienyl]-1,3,3-trimethyl-3H-indolium iodide; Hexacyanin 2; HIDCI. CAS No. 36536-22-8. Molecular formula: C27H31IN2. Mole weight: 510.45.
Hidrosmin
Hidrosmin is a biomedical product used in the research of chronic venous insufficiency. Synonyms: 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)?-β-D-glucopyranosyl]?oxy]?-5-(2-hydroxyethoxy)?-2-[3-(2-hydroxyethoxy)?-4-methoxyphenyl]?-, mixt. with 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)?-β-D-glucopyranosyl]?oxy]?-5-(2-hydroxyethoxy)?-2-(3-hydroxy-4-methoxyphenyl)?-4H-1-benzopyran-4-one and 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)?-β-D-glucopyranosyl]?oxy]?-5-hydroxy-2-[3-(2-hydroxyethoxy)?-4-methoxyphenyl]?-4H-1-benzopyran-4-one Mixture. CAS No. 218433-35-3. Molecular formula: C32H40O17.C30H36O16.C30H36O16.
Hidrosmin Impurity
Cas No. 120250-44-4.
Hierridin
Hierridin is a substance obtained from the lichen Ramalina hierrensis. CAS No. 142382-20-5. Molecular formula: C29H52O3. Mole weight: 448.72.
HIF-1 alpha (556-574)
HIF-1 alpha (556-574) is a short hypoxia-inducible factor-1 (HIF-1) 19 residues fragment. HIF-1 functions as master regulator of response to oxygen homeostasis [1]. Uses: Scientific research. Group: Peptides. CAS No. 1201633-99-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1888.
HIF-1α-IN-2
HIF-1α-IN-2 is an effective HIF-1α inhibitor with anticancer potencies ( IC 50 s of 28 nM and 15 nM in MDA-MB-231 and MiaPaCa-2 cells, respectively). HIF-1α-IN-2 suppresses HIF-1α expression by blocking transcription and protein translation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2762315-06-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115903.
HIF-1α-IN-4
HIF-1α-IN-4 is a HIF-1α inhibitor with an IC 50 value of 24 nM (in HEK293T cell). HIF-1α-IN-4 downregulates VEGF and PDK1 mRNA expressions under hypoxia. HIF-1α-IN-4 can be used in the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2826221-23-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151465.
HIF1-IN-3
HIF1-IN-3 (compound F4) is a potent HIF1 inhibitor with an EC 50 value of 0.9 μM. HIF1-IN-3 can be used for researching anticancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 333314-79-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-147029.
HIF-1 Signaling Pathway Compound Library
A unique collection of 1352 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies?- Covers PI3K-AKT, MAPK, Ubiquitination signaling pathways and targets such as HIF, HIF Prolyl-Hydroxylase, E1/E2/E3 Enzyme, PI3K, MAPK, Proteasome, etc. - Part of them are in clinical trial phase or FDA approved?- Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L8500. Categories: HIF-1 Signaling Pathway Compounds Libraries.
HIF-2α-IN-1
HIF-2α-IN-1 is a HIF-2α inhibitor with an IC50 value of less than 500 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1799948-06-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19949.
HIF-2α-IN-3
HIF-2α-IN-3, an allosteric inhibitor of hypoxia inducible factor-2α ( HIF-2α ), exhibits an IC 50 of 0.4 μM and a K D of 1.1 μM. Anticancer agent [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 313964-19-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18370.
HIF-2a Translation Inhibitor 76
A cell-permeable HIF-2a translation inhibitor (IC50 value 5 μM). It inhibits HIF-2a translation via enhancing the binding of IRP1 (Iron-Regulatory Protein 1) to the IRE (Iron-Responsive Element) region at the 5' UTR of the HIF-2α mRNA. Synonyms: HIF-2a translation inhibitor; HIF-2|A-IN-4; 882268-69-1; methyl 3-[ (2E) -2-[cyano (methylsulfonyl) methylidene]hydrazinyl]thiophene-2-carboxylate; HIF-2alpha-IN-4; SCHEMBL781448; HMS554D20; Methyl 3- ( ([cyano (methanesulfonyl) methylidene]amino) amino) thiophene-2-carboxylate; CCG-45847; MS-24103; HY-136748; CS-0133535; SR-01000635592-1; methyl 3- (2- (cyano (methylsulfonyl) methylene) hydrazineyl) thiophene-2-carboxylate. Grades: 99%. CAS No. 882268-69-1. Molecular formula: C9H9N3O4S2. Mole weight: 287.32.
HiFi DNA Polymerase
HiFi DNA Polymerase. Hifi dna polymerase contains ta dna polymerase and a proofreading 3-5 exonuclease.hifi dna polymerase provides higher specificity and higher amplification efficiency than ta dna polymerase. two different buffers are provided in the kit. hifi pcr buffer i is optimized for the amplification of genomic dna and hifi pcr buffer ii is optimized for the amplification of λdna, cdna or plasmid dna. extension rate is about 1-2 kb/min. template-independent a can be generated at the 3 end of the pcr product. amplification of genomic dna fragment up to 15 kb. Group: Cloning Enzymes. Purity: 250U; 500U. Storage: Store at -20 ?. Cat No: CE-3022.
A cell-permeable phenoxyacrylamido compound that inhibits hypoxia-induced cellular HIF-1alpha accumulation in a manner similar to LW6 by upregulating Hippel-Lindau tumor suppressor gene product pVHL, but with much higher potency (IC50 = 120nM vs 2.44uM, respectively, against hypoxia-induced HRE reporter activity in HCT116 cells). Shown to suppress HIF-1 target genes expression in HCT116 cultures and inhibit HUVEC tubule formation (effective conc. ≥2uM) under hypoxia conditions. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
HIF Inhibitor VII (Hypoxia-Inducible Factor Inhibitor VI, N-(3-Chloro-5-fluorophenyl)-4-nitrobenzo[c][1, 2, 5]oxadiazol-5-amine)
A cell-permeable benzoxadiazolamine that prevents HIF-2alpha-HIF-beta/ARNT heterodimeration by perturbing HIF-2alpha Per-ARNT-Sim/PAS-B domain surface beta-sheet conformation via a 1:1 stoichiometric binding (KD = 81nM), while exhibiting no affinity toward HIF-1alphaPAS-B domain. Shown to be metabolically stable and non-cytotoxic in cultures and selectively inhibit hypoxia-induced HIF-2a DNA binding and HIF-2alpha-dependent EPO mRNA upregulation (1 to10uM for 6-12h), but not HIF-1alpha DNA binding or HIF-1alpha-dependent PGK1 mRNA upregulation, in Hep3B cells. Unlike HIF Inhibitors I-VI, this compound does not affect the cellular protein or mRNA levels of HIF-1alpha & HIF-2alpha. Group: Biochemicals. Grades: Highly Purified. CAS No. 1422955-31-4. Pack Sizes: 10mg. Molecular Formula: C??H?ClFN?O?, Molecular Weight: 308.65. US Biological Life Sciences.
Worldwide
HiFi Pfu DNA Polymerase
HiFi Pfu DNA Polymerase. Hifi pfu dna polymerase is an engineered version of pfu dna polymerase with enhanced yield and higher fidelity. ehifi pfu dna polymerase possesses a proofreading 3'-5' exonuclease activity. hifi pfu dna polymerase offers high fidelity. extension rate is about 0.5 kb/min. amplification of genomic dna fragment up to 6 kb. amplification of plasmid dna fragment up to 10 kb. Group: Cloning Enzymes. Purity: 250U; 500U. Storage: Store at -20 ?. Cat No: CE-3001.
HIF Phd Inhibitor 4
An inhibitor of the Hypoxia Inducible Factor (HIF) Prolyl-Hydroxylases (PHD). Synonyms: N-(4-Chlorobenzyl)-3-(5,6-dimethoxy-2-pyridinyl)-2,4-dioxo-1. Grades: 98%. CAS No. 1227946-51-1. Molecular formula: C21H17ClN4O5S. Mole weight: 472.9.
HIF-PHD Inhibitor II, JNJ-42041935 (HIF Prolyl Hydroxylase Inhibitor II, 1-(5-Chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic Acid)
A cell-permeable benzimidazolopyrazole compound that acts as an active-site binding, iron insensitive, 2-oxoglutarate competitive, reversible and potent inhibitor of PHD1, 2 and 3 isozymes (pKi=7.91, 7.29 and 7.65, respectively). Displays >100-fold selectivity over FIH (factor inhibiting hydroxylase; pIC50 ~4) and minimal affinity towards a panel of receptors, enzymes and kinases. Shown to elevate HIF-1a levels in Hep3B cells and stimulate erythropoietin secretion in mice, and reverse inflammation-induced anemia in rats (100uM/kg). Shown to inhibit malate dehydrogenase 2 (MDH2) activity and suppress mitochondrial respiration. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H?ClF?N?O?, Molecular Weight: 346.7. US Biological Life Sciences.
Worldwide
Higenamine
Higenamine. Group: Biochemicals. Alternative Names: 1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-6,7-Isoquinolinediol;(+/-)-1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-6,7-Isoquinolinediol; (+/-)-O-demethyl-Coclaurine; (RS)-Norcoclaurine; (+/-)-Demethylcoclaurine; (+/-)-Norcoclaurine; (+/-)-O-Demethylcoclaurine; dl-Demethylcoclaurine. Grades: Highly Purified. CAS No. 5843-65-2. Pack Sizes: 25mg. Molecular Formula: C16H17NO3, Molecular Weight: 271.31. US Biological Life Sciences.
Worldwide
Higenamine
Higenamine (Norcoclaurine), a β2-AR agonist with antioxidant capability, is a key component of the Chinese herb aconite root that prescribes for treating symptoms of heart failure in the oriental Asian countries. Higenamine is also a α1-adrenergic receptor antagonist with hypotensive effect. is a selective LSD1 inhibitor ( IC 50 =1.47 μM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine protects myocyte Apoptosis and ischemia/reperfusion (I/R) injury through selective activation of beta2-adrenergic receptor ( β2-AR ). Higenamine also reduces I/R-induced myocardial infarction in mice. Higenamine can attenuate IL-1β-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine can be used to study cancer, inflammation, cardiorenal syndrome and other diseases [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11]. Uses: Scientific research. Group: Natural products. Alternative Names: Norcoclaurine; Demethyl-Coclaurine. CAS No. 5843-65-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N2037.
Higenamine hydrochloride
Higenamine hydrochloride is a selective LSD1 inhibitor ( IC 50 =1.47 μM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine (Norcoclaurine) can attenuate IL-1β-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine hydrochloride protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine hydrochloride can be used to study cancer, inflammation, cardiorenal syndrome and other diseases [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: Norcoclaurine hydrochloride. CAS No. 11041-94-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-N2037A.
Higenamine Hydrochloride
Formula: Group: Biochemicals. Grades: Plant Grade. CAS No. 11041-94-4. Pack Sizes: 20mg. US Biological Life Sciences.
Worldwide
High concentration carboxyl MWCNTs water paste(~13wt%)
Carbon black oil appears as a dark colored liquid with a petroleum-like odor. Less dense than water and insoluble in water. Vapors heavier than air.;Carbon, activated is a black grains that have been treated to improve absorptive ability. May heat spontaneously if not properly cooled after manufacture.;Carbon, animal or vegetable origin appears as a black powder or granular mixed with a tar or starch and water binder pressed into regular lumps or briquettes. Heats slowly and ignites in air especially if wet.;Graphite (natural) appears as a mineral form of the element carbon. Hexagonal crystals or thin leaf-like layers. Steel-gray to black with a metallic luster and a greasy feel. An electrical conductor. Used for high-temperature crucibles, as a lubricant and in "lead" pencils.;DryPowder; DryPowder, Liquid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, WetSolid, OtherSolid, Liquid; DryPowder, WetSolid, Liquid; Liquid; OtherSolid; OtherSolid, GasVapor, Liquid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid, Liquid; WetSolid; WetSolid, Liquid;OtherSolid; PelletsLargeCrystals;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSolid;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; DryPowder, WetSolid; Liquid; OtherSolid; PelletsLargeCrystals; PelletsLargeCr
High concentration MWCNTs water paste(~14wt%)
Carbon black oil appears as a dark colored liquid with a petroleum-like odor. Less dense than water and insoluble in water. Vapors heavier than air.;Carbon, activated is a black grains that have been treated to improve absorptive ability. May heat spontaneously if not properly cooled after manufacture.;Carbon, animal or vegetable origin appears as a black powder or granular mixed with a tar or starch and water binder pressed into regular lumps or briquettes. Heats slowly and ignites in air especially if wet.;Graphite (natural) appears as a mineral form of the element carbon. Hexagonal crystals or thin leaf-like layers. Steel-gray to black with a metallic luster and a greasy feel. An electrical conductor. Used for high-temperature crucibles, as a lubricant and in "lead" pencils.;DryPowder; DryPowder, Liquid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, WetSolid, OtherSolid, Liquid; DryPowder, WetSolid, Liquid; Liquid; OtherSolid; OtherSolid, GasVapor, Liquid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid, Liquid; WetSolid; WetSolid, Liquid;OtherSolid; PelletsLargeCrystals;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSolid;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; DryPowder, WetSolid; Liquid; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, O
High Concentration Ti3C2 MXene Printing Paste
multi-layer/few-layer MXene material. Uses: Flexible electronic devices (sensors, capacitors), flexible batteries, etc. it can be used to deposit and load other materials to make composite materials and separation membranes for seawater separation. Group: Mxenes materials. CAS No. 12363-89-2.
High Conductive Carbon MWNT
High Conductive Carbon MWNT. Group: Multi wall cnt. CAS No. 308068-56-6. >99wt% (MWNT).
High-Density Polyethylene
HDPE is a type of polyethylene, the most common plastic which accounts for over 34% of the global plastic market. It is a polymer made up of a huge number of repeating units (known as monomers). The branching in high-density polyethylene is of a relatively low degree (when compared to other categories of polyethylene). Uses: Bottle caps and bottles are made of this polymer. it is also used in 3-d printing filaments hdpe is used in the fuel tanks of several types of automobiles. the piping system responsible for the distribution of natural gas is generally made of this polymer due to its resistance to corrosion and other attributes. it is used in plastic lumber and wood plastic composites. skeletal and facial reconstruction surgeries (part of plastic surgery) involve the use of hdpe. Group: Food grade plastic.
High-Entropy Alloy Powder (CrMnFeCoNi)
We are engaged in the development, production, and sales of High-Entropy Alloy Powder (CrMnFeCoNi) and provide personalized customization service for high-quality metal powder. FeMoCoCr high entropy alloy spherical powder is a new alloy with very unique properties. Uses: Laser/electron beam additive manufacturing (slm / ebm) powder metallurgy (pm) laser cladding, laser direct deposition (dld) powder hot isostatic pressing (hip) metal injection mold molding (mim). Group: High entropy alloys. Pack Sizes: Our High-Entropy Alloy Powder (CrMnFeCoNi) is carefully handled during storage and transportation to preserve the quality of our product in its original condition. Double plastic bags in the iron drum, 200kg/piece. Or according to the needs of customers.
High Flexible Thermal Graphite Film
High Flexible Thermal Graphite Film. Group: Pyrolitic graphite. CAS No. 7782-42-5.
High Glossiness Benzene-Soluble Polyamide Resin
This product is a high glossiness polyamide resin with low molecular weight has excellent properties and inter-solubility with nitrocellulose. When these resins are used with pigment additives, the final product will display bright colors and gloss. Uses: The types of resins are used in the following items, such as gravure printing inks, paper inks, plastic film printing inks, overprinting varnishes etc. Group: Benzene soluble polyamide resins.
Highly oriented pyrolytic graphite Grade A(Size: 10x10x1.0mm). Uses: Designed for use in research and industrial production. Product Category: Highly Oriented Pyrolytic Graphite. CAS No. 7440-44-0. Product ID: ACM7440440-122. Alfa Chemistry ISO 9001:2015 Certified.
Highly oriented pyrolytic graphite Grade A(Size:20x20x1.0 mm). Uses: Designed for use in research and industrial production. Product Category: Highly Oriented Pyrolytic Graphite. CAS No. 7440-44-0. Product ID: ACM7440440-72. Alfa Chemistry ISO 9001:2015 Certified.
Highly oriented pyrolytic graphite Grade A(Size: 20x20x(1.6~2.0)mm). Uses: Designed for use in research and industrial production. Product Category: Highly Oriented Pyrolytic Graphite. CAS No. 7440-44-0. Product ID: ACM7440440-37. Alfa Chemistry ISO 9001:2015 Certified.