A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
hVEGF-IN-1 inhibits human VEGF-A translation and has antitumor activity. Tumor bearing mice treated with hVEGF-IN-1 have an average tumor volume of less than 300 mm. The tumor weight in the presence of hVEGF-IN-1 reduces around 60.1% to a final weight of 0.18 g. No significant change in body weight is observed during the treatment. Synonyms: 1-Piperazinepropanamide, N-[2-[4-[[4-[2-(diethylamino)ethoxy]phenyl]amino]-2-quinazolinyl]phenyl]-4-methyl. CAS No. 1637443-98-1. Molecular formula: C34H43N7O2. Mole weight: 581.75.
hVEGF-IN-3
hVEGF-IN-3 (compound 9) is a potent hVEGF inhibitor. hVEGF-IN-3 inhibits HT-29, MCF-7, and HEK-293 cells proliferation with IC 50 s of 61, 142, and 114 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 46739-60-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-160811.
recombinant, expressed in Hi-5 Insect cells, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
HWL-088
HWL-088 is a highly potent and orally active agonist of free fatty acid receptor 1 (FFA1/GPR40) with an EC50 of 18.9 nM. HWL-088 improves glucose and lipid metabolism. It has anti-diabetic effects and moderate PPARδ activity with an EC50 of 570.9 nM. Synonyms: 2-(2-fluoro-4-((2'-methyl-[1,1'-biphenyl]-3-yl)methoxy)phenoxy)acetic acid; {2-Fluoro-4-[(2'-methyl-3-biphenylyl)methoxy]phenoxy}acetic acid; Acetic acid, 2-[2-fluoro-4-[(2'-methyl[1,1'-biphenyl]-3-yl)methoxy]phenoxy]-. Grade: ≥98%. CAS No. 2378617-96-8. Molecular formula: C22H19FO4. Mole weight: 366.38.
An isoquinolinium derivative that inhibits the proliferation of wilde-type and all mutants of Schizosaccharomyces pombe. Group: Biochemicals. Alternative Names: 3, 4-Di hydro-2- [4- (2, 2-di methyl ethyl ) benzyl ] -6-fluoro-1-undacanyl isoquinolinium Bromide. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
HWY 5069
HWY 5069. Group: Biochemicals. Alternative Names: 3, 4-Di hydro-2- [4- (2, 2-di methyl ethyl ) benzyl ] -6-fluoro-1-undacanyl isoquinolinium bromide. Grades: Highly Purified. CAS No. 914917-58-1. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C31H45BrFN. US Biological Life Sciences.
HX531 is an orally active RXR antagonist with an IC50 of 18 nM. HX531 upregulates the p53-p21Cip1 pathway. HX531 abrogates the anti-apoptotic effect of t-RA. HX531 exerts anti-obesity, anti-diabetic and anti-melanoma activities[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 188844-34-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-108521.
HX 531
HX 531 is a potent RXR antagonist (IC50 = 18 nM) that inhibits 9-cis retinoic acid-induced transactivation of RXR. HX 531 promotes the differentiation of white and brown pre-adipocyte to white adipocytes, and reduces triglyceride content in white adipose tissue, skeletal muscle, and the liver of mice given a high fat diet. Synonyms: HX 531; HX-531; HX531. 4-(7,8,9,10-Tetrahydro-5,7,7,10.10-pentamethyl-2-nitro-5H-benzo[b]naphtho[2,3-e][1,4]-diazepin-12-yl)-benzoic acid. Grade: ≥98% by HPLC. CAS No. 188844-34-0. Molecular formula: C29H29N3O4. Mole weight: 483.56.
HX 531
HX 531 is a novel RXR antagonist used to enhance transactivation of PPARγ and ST 13 preadipocyte differentiation. Helps in the reduction of triglyceride content in white adipose tissue, skeletal muscle and liver. Group: Biochemicals. Grades: Highly Purified. CAS No. 188844-34-0. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C29H29N3O4, Molecular Weight: 483.56. US Biological Life Sciences.
Worldwide
HX600
HX600 is a synthetic agonist for RXR (Retinoid X Receptor) heterodimer complex. HX600 prevents ischemia-induced neuronal damage. HX600 has orally bioactivity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 172705-89-4. Pack Sizes: 1 mg. Product ID: HY-120875.
HX600
HX600 is a synthetic agonist for RXR-Nurr1 heterodimer complex. It prevents ischemia-induced neuronal damage. Synonyms: HX-600; HX 600; (Z)-4-(5,7,7,10,10-Pentamethyl-7,8,9,10-tetrahydro-5H-benzo[b]naphtho[2,3-e][1,4]diazepin-12-yl)benzoic acid. Grade: 99%. CAS No. 172705-89-4. Molecular formula: C29H30N2O2. Mole weight: 438.56.
HX-603
HX-603 is a RXR agonist. Synonyms: 4-(7,7,10,10-tetramethyl-5-propyl-8,9-dihydronaphtho[2,3-b][1,5]benzodiazepin-12-yl)benzoic acid; HX-603; HX 603; HX603. Grade: >98%. CAS No. 259228-72-3. Molecular formula: C31H34N2O2. Mole weight: 466.625.
HX 630
HX 630 is a potent RXR agonist that acts as a retinoid synergist. HX 630 suppresses proliferation of vascular smooth muscle cells (VSMCs) in vivo and in vitro. It was shown to enhance ABCA1 mRNA expression and apoA-I-dependent cellular cholesterol release in differentiated THP-1 cells. Synonyms: HX 630; HX630; HX-630; 4-(7,8,9,10-Tetrahydro-7,7,10,10-tetramethylbenzo[b]naphtho[2,3-f][1,4]thiazepin-12-yl-benzoic acid. Grade: ≥98% by HPLC. CAS No. 188844-52-2. Molecular formula: C28H27NO2S. Mole weight: 441.58.
HY-17542 is a potent inhibitor of papain-like protease (PLpro) with IC50 of 2.6 μM. Synonyms: PLpro inhibitor 6; (R)-5-acetamido-2-methyl-N-(1-(naphthalen-1-yl)ethyl)benzamide; HY 17542; HY17542. Grade: >98%. CAS No. 1093070-14-4. Molecular formula: C22H22N2O2. Mole weight: 346.43.
Hyacinthacine A2
Hyacinthacine A2 is a remarkable antifungal compound extracted from Hyacinthaceae plants, aiding in studying a myriad of fungal infections, encompassing candidiasand aspergillosis. Molecular formula: C8H15NO3. Mole weight: 173.21.
Hyacinthacine B3
Hyacinthacine B3 is a potent compound used to study bacterial infections exhibiting antimicrobial activity against a variety of pathogens, including multidrug-resistant strains. Synonyms: Hyacinthacine B3; CHEMBL524631; BDBM50278912; (1S,2R,3R,5R,7R,8R)-3-(hydroxymethyl)-5-methyl-2,3,5,6,7,8-hexahydro-1H-pyrrolizine-1,2,7-triol. Molecular formula: C9H17NO4. Mole weight: 203.24.
Hyalodendrin
Hyalodendrin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Hyalodendrin;1-(hydroxymethyl)-5,7-dimethyl-4-(phenylmethyl)- 2,3-dithia-5,7-diazabicyclo(2.2.2)octane-6,8-dione; (-)-isomer of hyalodendrin 2-benzyl-1,4-dimethyl-5-hydroxymethyl--2,5-epi-dithia-3,6-diketopiperazi. Product Category: Heterocyclic Organic Compound. CAS No. 51920-94-6. Molecular formula: C14H16N2O3S2. Mole weight: 324.42. Product ID: ACM51920946. Alfa Chemistry ISO 9001:2015 Certified.
HYALTEMPO
[4-N-(4-amino-2,2,6,6-tetramethylpiperidine-1-oxyl)] hyaluron amine. non-specific esterase hydrolysistraps probe in the cytosol. Product ID: 9-00254. Properties: yellow solid. Source : Reference: EMBO J., 16, 3533, 1997; Am. J. Pathol., 152, 231, 1998.
Hyaluronan mediated motility receptor (165-173) is a bioactive peptide of Hyaluronan mediated motility receptor, a receptor for hyaluronic acid (HA). Hyaluronan mediated motility receptor is also involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity. Synonyms: Intracellular hyaluronic acid-binding protein (165-173); HMMR (165-173); RHAMM (165-173); Receptor for hyaluronan-mediated motility (165-173).
hyaluronan synthase
The enzyme from Streptococcus Group A and Group C requires Mg2+.The enzyme adds GlcNAc to nascent hyaluronan when the non-reducing end is GlcA, but it adds GlcA when the non-reducing end is GlcNAc. The enzyme is highly specific for UDP-GlcNAc and UDP-GlcA; no copolymerization is observed if either is replaced by UDP-Glc, UDP-Gal, UDP-GalNAc or UDP-GalA. Similar enzymes have been found in a variety of organisms. Group: Enzymes. Synonyms: spHAS; seHAS. Enzyme Commission Number: EC 2.4.1.212. CAS No. 39346-43-5. Hyaluronan synthase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2440; hyaluronan synthase; EC 2.4.1.212; 39346-43-5; spHAS; seHAS. Cat No: EXWM-2440.
Hyaluronan synthase from Pasteurella multocida, Recombinant
Hyaluronan synthases (HAS) are membrane-bound enzymes which use UDP-α-N-acetyl-D-glucosamine and UDP-α-D-glucuronate as substrates to produce the glycosaminoglycan hyaluronan at the cell surface and extrude it through the membrane into the extracellular space. Group: Enzymes. Synonyms: EC 2.4.1.212; spHAS; seHAS; Hyaluronan synthases; HAS. Enzyme Commission Number: EC 2.4.1.212. CAS No. 39346-43-5. Purity: min 95% by SDS-PAGE. Hyaluronan synthase. Source: E. coli. Species: Pasteurella multocida. EC 2.4.1.212; spHAS; seHAS; Hyaluronan synthases; HAS. Cat No: NATE-1485.
Hyaluronate fluorescein - MW - 800kDa is an intricate fusion of hyaluronate and fluorescein facilating the deep research of maladies, like cancer, arthritis and diverse cutaneous afflictions. Synonyms: Fluorescein hyaluronic acid.
Hyaluronate Hexasaccharide is a fragment of hyaluronic acid (HA) and can be used as a biochemical assay reagent. Hyaluronate is a naturally occurring glycosaminoglycan found in various connective tissue of humans. Synonyms: Hyaluronic acid hexasaccharide; L-GulA(a1-3)L-GulNAc(a1-4)L-GulA(a1-3)L-GulNAc(a1-4)L-GulA(a1-3)L-GulNAc; alpha-L-gulo-hexospyranosyluronic acid-(1->3)-2-acetamido-2-deoxy-alpha-L-gulo-hexopyranosyl-(1->4)-alpha-L-gulo-hexospyranosyluronic acid-(1->3)-2-acetamido-2-deoxy-alpha-L-gulo-hexopyranosyl-(1->4)-alpha-L-gulo-hexospyranosyluronic acid-(1->3)-2-acetamido-2-deoxy-L-gulo-hexopyranose. CAS No. 73603-40-4. Molecular formula: C42H65N3O34. Mole weight: 1155.97.
hyaluronate lyase
The enzyme catalyses the degradation of hyaluronan by a β-elimination reaction. Also acts on chondroitin. The product is more systematically known as 3-(4-deoxy-α-L-threo-hex-4-enopyranosyluronic acid)-2-acetamido-2-deoxy-D-glucose. Group: Enzymes. Synonyms: hyaluronidase (ambiguous); glucuronoglycosaminoglycan lyase (ambiguous); spreading factor; mucinase (ambiguous). Enzyme Commission Number: EC 4.2.2.1. CAS No. 37259-53-3. Hyaluronate Lyase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5084; hyaluronate lyase; EC 4.2.2.1; 37259-53-3; hyaluronidase (ambiguous); glucuronoglycosaminoglycan lyase (ambiguous); spreading factor; mucinase (ambiguous). Cat No: EXWM-5084.
Hyaluronate lyase from Streptococcus equi, Recombinant
Hyaluronate lyase degrades hyaluronate using an elimination reaction to break glycosidic linkages yielding unsaturated disaccharide products. Group: Enzymes. Synonyms: hyaluronidase; glucuronoglycosaminoglycan lyase; spreading factor; mucinase; 37259-53-3; EC 4.2.2.1; hyaluronate lyase. Enzyme Commission Number: EC 4.2.2.1. CAS No. 37259-53-3. Purity: > 95 % as judged by SDS-PAGE. Hyaluronate Lyase. Mole weight: 38447.1 Da. Activity: 4.6 U/mg. Storage: Store at 4°C (shipped at room temperature). Form: Supplied in 3.2 M ammonium sulphate. Source: Streptococcus equi 4047. hyaluronidase; glucuronoglycosaminoglycan lyase; spreading factor; mucinase; 37259-53-3; EC 4.2.2.1; hyaluronate lyase. Cat No: NATE-1210.
Hyaluronate Lyase from Streptococcus pyogenes, Recombinant
Hyaluronate lyase degrades hyaluronate using an elimination reaction to break glycosidic linkages yielding unsaturated disaccharide products. It is important for the diffusion of toxins and proteins produced by S. pyogenes. Group: Enzymes. Synonyms: hyaluronidase; glucuronoglycosaminoglycan lyase; spreading factor; mucinase; 37259-53-3; EC 4.2.2.1; hyaluronate lyase. Enzyme Commission Number: EC 4.2.2.1. CAS No. 37259-53-3. Hyaluronate Lyase. Activity: > 8.0 units/mg protein (5.0-15.0 mg/mL). Storage: 2-8°C. Form: ammonium sulfate suspension. Source: E. coli. Species: Streptococcus pyogenes. hyaluronidase; glucuronoglycosaminoglycan lyase; spreading factor; mucinase; 37259-53-3; EC 4.2.2.1; hyaluronate lyase. Cat No: NATE-0346.
Hyaluronate lyase from Streptomyces coelicolor, Recombinant
Hyaluronate lyase degrades hyaluronate using an elimination reaction to break glycosidic linkages yielding unsaturated disaccharide products. Group: Enzymes. Synonyms: hyaluronidase; glucuronoglycosaminoglycan lyase; spreading factor; mucinase; 37259-53-3; EC 4.2.2.1; hyaluronate lyase. Enzyme Commission Number: EC 4.2.2.1. CAS No. 37259-53-3. Purity: > 95 % as judged by SDS-PAGE. Hyaluronate Lyase. Mole weight: 82914.2 Da. Activity: 8.1 U/mg. Storage: Store at 4°C (shipped at room temperature). Form: Supplied in 3.2 M ammonium sulphate. Source: Streptomyces coelicolor A3(2). hyaluronidase; glucuronoglycosaminoglycan lyase; spreading factor; mucinase; 37259-53-3; EC 4.2.2.1; hyaluronate lyase. Cat No: NATE-1211.
Hyaluronate-SS-PCL is a kind of hyaluronic acid polymerized polyester connected by disulfide bond.Polycaprolactone (PCL) is a kind of poly (caprolactone) which is polymerized by ring opening polymerization ofε-caprolactone with organometallic compounds (such as tetraphenyltin) as catalyst and dihydroxy or trihydroxy as initiator. It is widely used in drug carriers, nanofiber spinning, organic colorants, powder coatings and other fields. Synonyms: Hyaluronate-S-S-Poly(ε-caprolactone). Product ID: MSMN-058. Category: Raw Materials.
Hyaluronic acid (corn fermented) is a biopolymer composed of repeating units of disaccharides with various applications. Uses: Scientific research. Group: Natural products. Alternative Names: Hyaluronan; Hyaluronate. CAS No. 9004-61-9. Pack Sizes: 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-B0633A.
Hyaluronic acid
HA. Grades: medical grade. CAS No. 9067-32-7. Product ID: 8-01250. Mole weight: Mw 150-500 kDa. Properties:
Hyaluronic acid
For whitening and moisturizing. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Hyaluronic Acid Sodium Salt. Product Category: Material of cosmetics. Appearance: White powder. CAS No. 9004-61-9. Molecular formula: C28H44N2O23. Mole weight: 403.31. Density: 1.78 g/cm³. Product ID: ACM9004619. Alfa Chemistry ISO 9001:2015 Certified.
Hyaluronic acid
HA. Grades: medical grade. CAS No. 9067-32-7. Product ID: 8-01251. Mole weight: Mw 500-1,000 kDa.
Hyaluronic acid
HA. Grades: medical grade. CAS No. 9067-32-7. Product ID: 8-01252. Mole weight: Mw 1,000-1,700kDa.
Hyaluronic acid
HA. antiglaucoma agent. Grades: cosmetic grade. CAS No. 9067-32-7. Product ID: 8-01360. Purity: 1% aqueous solution. Source : Reference: Arch. Ophth., 113, 985, 1995; J. Glaucoma, 4, 306, 1995.
Hyaluronic acid
HA. Grades: medical grade. CAS No. 9067-32-7. Product ID: 8-01254. Mole weight: Mw 2,500 -3,500 kDa. Properties: 500,000 IU/g.
Hyaluronic acid
HA. Grades: medical grade. CAS No. 9067-32-7. Product ID: 8-01253. Mole weight: Mw 1,800-2,500 kDa.