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A multisubunit non-phosphorylated ATPase that is involved in the transport of ions. Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1). The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases. All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 α- and 3 β-subunits) is connected via the Δ-subunit to the membrane sector by several smaller subunits. Within this complex, the γ- and ε-subunits, as well as the 9-12 c subunits rotate by consecutive 120° angles and perform...cal conditions, they pump H+ rather than synthesize ATP. Group: Enzymes. Synonyms: ATP synthase; F1-ATPase; FoF1-ATPase; H+-transporting ATPase; mitochondrial ATPase; coupling factors (F0, F1 and CF1); chloroplast ATPase; bacterial Ca2+/Mg2+ ATPase. Enzyme Commission Number: EC 7.1.2.2 (Formerly EC 3.6.3.14). Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4650; H+-transporting two-sector ATPase; EC 3.6.3.14; ATP synthase; F1-ATPase; FoF1-ATPase; H+-transporting ATPase; mitochondrial ATPase; coupling factors (F0, F1 and CF1); chloroplast ATPase; bacterial Ca2+/Mg2+ ATPase. Cat No: EXWM-4650.
hTrkA-IN-1 is a potent and orally active TrkA kinase inhibitor (IC50 = 1.3 nM), which can be used for the study of inflammatory disease, such as prostatitis, pelvic, et al. (Extracted from patent WO2015175788, compound 2). Synonyms: Urea, N-[(3S,4R)-4-(3-fluorophenyl)-1-(2-methoxyethyl)-3-pyrrolidinyl]-N'-[4-methyl-3-(2-methyl-5-pyrimidinyl)-1-phenyl-1H-pyrazol-5-yl]-; 1-((3S,4R)-4-(3-fluorophenyl)-1-(2-methoxyethyl)pyrrolidin-3-yl)-3-(4-methyl-3-(2-methylpyrimidin-5-yl)-1-phenyl-1H-pyrazol-5-yl)urea; BLN64892. Grade: ≥90%. CAS No. 1824664-89-2. Molecular formula: C29H32FN7O2. Mole weight: 529.61.
H-Trp-2-Chlorotrityl Resin
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis.
Tryptophanyl-asparagine is a dipeptide composed of Tryptophan and asparagine. Synonyms: Trp-Asn. CAS No. 175027-11-9. Molecular formula: C15H18N4O4. Mole weight: 318.33.
H-Trp-beta-ala-oh
H-Trp-beta-ala-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: L-TRYPTOPHYL-BETA-ALANINE;H-TRP-BETA-ALA-OH;L-TRYPTOPHYL-B-ALANINE. Product Category: Heterocyclic Organic Compound. CAS No. 67607-64-1. Molecular formula: C14H17N3O3. Mole weight: 275.3. Purity: 0.96. IUPACName: H-TRP-β-ALA-OH. Product ID: ACM67607641. Alfa Chemistry ISO 9001:2015 Certified.
H-Trp-betana
H-Trp-betana. Uses: Designed for use in research and industrial production. Additional or Alternative Names: EINECS 222-044-1, CID102979, (S)-alpha-Amino-N-2-naphthyl-1H-indole-3-propionamide, 3326-63-4. Product Category: Heterocyclic Organic Compound. CAS No. 3326-63-4. Molecular formula: C21H19N3O. Mole weight: 329.4. Purity: 0.96. IUPACName: 2-amino-3-(1H-indol-3-yl)-N-naphthalen-2-ylpropanamide. Density: 1.315g/cm³. Product ID: ACM3326634. Alfa Chemistry ISO 9001:2015 Certified.
H-Trp(Boc)-2-Chlorotrityl Resin
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis.
H-Trp(Boc)-2-Cl-Trt Resin
Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Group: Amino acid 2-cl-trt resins. Alternative Names: Nin-Boc-L-tryptophan-2-chlorotrityl resin. Pack Sizes: 5g, 25g.
H-Trp-met-asn-phe-nh2. Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-Trp-Met-Asn-Phe-NH2. Product Category: Heterocyclic Organic Compound. CAS No. 78758-93-7. Molecular formula: C29H37N7O5S. Product ID: ACM78758937. Alfa Chemistry ISO 9001:2015 Certified.
H-Trp-phe-oh
H-Trp-phe-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-Trp-Phe-OH;L-Tryptophyl-L-phenylalanine. Product Category: Heterocyclic Organic Compound. CAS No. 6686-2-8. Molecular formula: C20H21N3O3. Product ID: ACM1748091. Alfa Chemistry ISO 9001:2015 Certified.
H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA
H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA is the chromogenic substrate for Pin1, an important and conserved mitotic peptidyl-prolyl isomerase (PPIase) that specifically recognizes the phosphoserine-proline bonds present in mitotic phosphoproteins (kcat/Km = 20160 mM-1s-1). Synonyms: L-Argininamide, L-tryptophyl-L-phenylalanyl-L-tyrosyl-O-phosphono-L-seryl-L-prolyl-N-(4-nitrophenyl)-; L-Tryptophyl-L-phenylalanyl-L-tyrosyl-O-phosphono-L-seryl-L-prolyl-N-(4-nitrophenyl)-L-argininamide; WFY(p)SPR-pNA. CAS No. 202739-41-1. Molecular formula: C49H59N12O13P. Mole weight: 1055.05.
H-Trp-trp-gly-lys-lys-tyr-arg-ala-ser-lys-leu-gly-leu-ala-arg-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: [TRP63,64]-C3A (63-77);(TRP63,TRP64)-C3A (63-77);TRP-TRP-GLY-LYS-LYS-TYR-ARG-ALA-SER-LYS-LEU-GLY-LEU-ALA-ARG;WWGKKYRASKLGLAR;H-TRP-TRP-GLY-LYS-LYS-TYR-ARG-ALA-SER-LYS-LEU-GLY-LEU-ALA-ARG-OH. Product Category: Heterocyclic Organic Compound. Appearance: White powder. CAS No. 130154-64-2. Molecular formula: C86H134N26O18. Mole weight: 1820.15. Product ID: ACM130154642. Alfa Chemistry ISO 9001:2015 Certified.
H-Trp-Trp-Trp-OH
It is a highly hydrophobic tripeptide used as a model in phase distribution studies. Synonyms: Trp-Trp-Trp; L-Tryptophyl-L-tryptophyl-L-tryptophan; (S)-2-[(S)-2-[(S)-2-Amino-3-(1H-indol-3-yl)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-3-(1H-indol-3-yl)-propionic acid. CAS No. 59005-82-2. Molecular formula: C33H32N6O4. Mole weight: 576.65.
H-Trp-val-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-TRP-VAL-OH;L-TRYPTOPHYL-L-VALINE;L-TRYPTOPHAN VALINE;TRP-VAL;TRP-VAL CRYSTALLINE. Product Category: Heterocyclic Organic Compound. CAS No. 24613-12-5. Molecular formula: C16H21N3O3. Mole weight: 303.36. Purity: 0.96. IUPACName: 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]-3-methylbutanoic acid. Density: 1.268g/cm³. Product ID: ACM24613125. Alfa Chemistry ISO 9001:2015 Certified.
H-Trp-Val-OH
H-Trp-Val-OH is an effective non-competitive inhibitor of xanthine oxidase, and also inhibits DPP IV, contrary to the inverse dipeptide. Synonyms: H-WV-OH; L-tryptophyl-L-valine; tryptophanyl-valine; L-Trp-L-Val-OH; (S)-2-[(S)-2-Amino-3-(1H-indol-3-yl)-propionylamino]-3-methyl-butyric acid. Grade: ≥95% by HPLC. CAS No. 24613-12-5. Molecular formula: C16H21N3O3. Mole weight: 303.35.
H-Trp-val-ome. hcl
H-Trp-val-ome. hcl. Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-TRP-VAL-OME · HCL; H-TRP-VAL-OME.HCL. Product Category: Heterocyclic Organic Compound. CAS No. 92410-11-2. Molecular formula: C17H23N3O3.HCl. Mole weight: 353.844. Purity: 0.96. IUPACName: L-Valine, N-L-tryptophyl-, methyl ester, monohydrochloride. Product ID: ACM92410112. Alfa Chemistry ISO 9001:2015 Certified.
hTRT (615-624)
Human telomerase reverse transcriptase is a catalytic subunit of the enzyme telomerase, which, together with the telomerase RNA component (TERC), comprises the most important unit of the telomerase complex. Synonyms: Human telomerase reverse transcriptase (615-624).
hTRT (988-997)
Human telomerase reverse transcriptase is a catalytic subunit of the enzyme telomerase, which, together with the telomerase RNA component (TERC), comprises the most important unit of the telomerase complex. Synonyms: Human telomerase reverse transcriptase (988-997).
HTS01037
HTS01037, a high-affinity ligand of adipocyte fatty acid binding protein (A-FABP/aP2) (Ki = 0.67 μM), and is a competitive antagonist of protein-protein interactions mediated by AFABP/aP2 (Ki= 0.67 μM). Synonyms: HTS01037; HTS 01037; HTS-01037. 4-[(2-methoxycarbonyl-5-thiophen-2-ylthiophen-3-yl)amino]-4-oxobut-2-enoic acid; (E)-4-[(2-methoxycarbonyl-5-thiophen-2-ylthiophen-3-yl)amino]-4-oxobut-2-enoic acid; 4-{[2-(methoxycarbonyl)-5-(2-thienyl)-3-thienyl]amino}-4-oxo-2-butenoic acid. CAS No. 682741-29-3. Molecular formula: C14H11NO5S2. Mole weight: 337.37.
HTS07545
HTS07545 is a potent sulfide:quinone oxidoreductase (SQOR) inhibitor with an IC50 of 30 nM. HTS07545 reduces the decomposition rate of hydrogen sulfide (H2S). HTS07545 can be used in the research of heart failure and pancreatic ductal adenocarcinoma. Uses: Scientific research. Group: Signaling pathways. CAS No. 118666-03-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144439.
H-Type 2-APE-HSA
H-Type 2-APE-HSA. Synonyms: H Type II-APE-HAS.
H Type II-APD-BSA
H Type II-APD-BSA. Synonyms: H Type 2-APD-BSA.
H-Tyr-2-chlorotrityl resin
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-Tyr-Trt(2-Cl)-Resin; H-Tyr-Barlos Resin; L-Tyrosine 2-chlorotrityl resin.
H-Tyr-beta-ala-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: L-TYROSYL-BETA-ALANINE;H-TYR-BETA-ALA-OH;L-Tyrosyl-!-alanine. Product Category: Heterocyclic Organic Compound. CAS No. 79472-95-0. Molecular formula: C12H16N2O4. Mole weight: 252.27. Purity: 0.96. IUPACName: 3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoic acid. Canonical SMILES: C1=CC(=CC=C1CC(C(=O)NCCC(=O)O)N)O. Product ID: ACM79472950. Alfa Chemistry ISO 9001:2015 Certified.
H-Tyr(Bzl)-2-Chlorotrityl Resin
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis.
H-Tyr-gly-gly-phe-leu-D-arg-arg-ile-arg-pro-lys-leu-lys-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TYR-GLY-GLY-PHE-LEU-D-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS;YGGFLD-RRIRPKLK;(D-ARG6)-DYNORPHIN A (1-13);[D-ARG6]-DYNORPHIN A (1-13), PORCINE;DYNORPHIN A PORCINE [D-ARG6]-FRAGMENT 1-13;H-TYR-GLY-GLY-PHE-LEU-D-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-OH;dynorphin A D-arg. Product Category: Heterocyclic Organic Compound. CAS No. 75921-87-8. Molecular formula: C75H126N24O15. Mole weight: 1603.95. Purity: 0.96. IUPACName: 6-amino-2-[[2-[[6-amino-2-[[1-[2-[[2-[[2-[[2-[[2-[[2-[[2-[[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)p. Product ID: ACM75921878. Alfa Chemistry ISO 9001:2015 Certified.
H-Tyr-his-oh
H-Tyr-his-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-TYR-HIS-OH. Product Category: Heterocyclic Organic Compound. CAS No. 3788-44-1. Molecular formula: C15H18N4O4. Mole weight: 318.33. Purity: 0.96. IUPACName: (2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid. Canonical SMILES: C1=CC(=CC=C1CC(C(=O)NC(CC2=CN=CN2)C(=O)O)N)O. Product ID: ACM3788441. Alfa Chemistry ISO 9001:2015 Certified.
H-TYR-LEU-OH is a dipeptide from β-lactoglobulin and it shows ACE-inhibitory activity with an IC50 of 122.1 μmol. Synonyms: Tyrosylleucine; L-Tyrosyl-L-leucine; Tyr-leu; Tyrosyl-Leucine; (S)-2-((S)-2-Amino-3-(4-hydroxyphenyl)propanamido)-4-methylpentanoic acid. CAS No. 17355-10-1. Molecular formula: C15H22N2O4. Mole weight: 294.35.
H-Tyr-nca. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (S)-4-(4-Hydroxybenzyl)oxazolidine-2,5-dione; N-Carbonyl-L-Tyrosine Anhydride; L-Tyrosine-N-carboxyanhydride; TYROSINE, NCA; 2,5-Oxazolidinedione,4-[(4-hydroxyphenyl)methyl]-, (4S)-; H-TYR-NCA; (2,5-Oxazolidinedione,4-[(4-hydroxyphenyl)methyl]-, (4S)-; (4S)-4-[(4-Hydroxyphenyl)methyl]-2,5-oxazolidinedione. CAS No. 3415-8-5. Molecular formula: C10H9NO4. Mole weight: 207.18. Purity: 95%+. IUPACName: (4S)-4-[(4-hydroxyphenyl)methyl]-1,3-oxazolidine-2,5-dione. Canonical SMILES: C1=CC(=CC=C1CC2C(=O)OC(=O)N2)O. ECNumber: 608-948-2. Product ID: ACM3415085. Alfa Chemistry ISO 9001:2015 Certified.
H-TYR-NCA
H-TYR-NCA is used as a reactant in the synthesis of peptides. Synonyms: (S)-4-(4-Hydroxybenzyl)oxazolidine-2,5-dione; N-Carbonyl-L-Tyrosine Anhydride; L-Tyr-NCA; L-Tyrosine-N-carboxyanhydride. Grade: 95%. CAS No. 3415-8-5. Molecular formula: C10H9NO4. Mole weight: 207.18.
H-Tyr-obzl
H-Tyr-obzl. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Benzyl tyrosinate, l-Tyrosine, phenylmethyl ester, MolPort-006-672-177, CID307932, NSC206295, 42406-77-9. Product Category: Heterocyclic Organic Compound. CAS No. 42406-77-9. Molecular formula: C16H17NO3. Mole weight: 271.32. Purity: 0.96. IUPACName: benzyl 2-amino-3-(4-hydroxyphenyl)propanoate. Canonical SMILES: C1=CC=C(C=C1)COC(=O)C(CC2=CC=C(C=C2)O)N. Density: 1.222g/cm³. Product ID: ACM42406779. Alfa Chemistry ISO 9001:2015 Certified.
H-Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Leu-Thr-Arg-Pro-Arg-Tyr-NH2. Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Leu-Thr-Arg-Pro-Arg-Tyr-NH2. Product Category: Heterocyclic Organic Compound. CAS No. 179986-95-9. Product ID: ACM179986959. Alfa Chemistry ISO 9001:2015 Certified.
H-Tyr(tBu)-2-Chlorotrityl Resin
H-Tyr(tBu)-2-Chlorotrityl Resin.
H-Tyr(tBu)-2-Cl-Trt Resin
Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Group: Amino acid 2-cl-trt resins. Alternative Names: O-t-Butyl-L-tyrosine-2-chlorotrityl resin. Pack Sizes: 5g, 25g.
H-Tyr(tos)-oh.acetate
H-Tyr(tos)-oh.acetate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-TYR(TOS)-OH.ACETATE. Product Category: Heterocyclic Organic Compound. CAS No. 13504-89-7. Molecular formula: C16H17NO5S. Mole weight: 335.375. Purity: 0.96. IUPACName: (S)-(O)-Ts-Tyr-OH. Product ID: ACM13504897. Alfa Chemistry ISO 9001:2015 Certified.
H-Tyr-Tyr-OH (L-Tyrosyl-L-tyrosine) is an antihypertensive peptide. H-Tyr-Tyr-OH inhibits angiotensin I-converting enzyme ( ACE ) with an IC 50 value of 0.028 mg/mL. H-Tyr-Tyr-OH can be used for the research of high blood pressure [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L-Tyrosyl-L-tyrosine. CAS No. 1050-28-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-114782.
H-TYR-TYR-OH
Tyr-Tyr and Tyr-Tyr-Tyr efficiently inhibit angiotensin I-converting enzyme (ACE) from rabbit lung, their IC50 values were 34 μM and 51 μM, respectively. These two tyrosine peptides exhibited a mix of competitive and noncompetitive inhibitions. Synonyms: Tyr-tyr; Tyrosyltyrosine; L-Tyrosyl-L-tyrosine; Peptide tyrosine-tyrosine; L-Tyr-L-Tyr; N-L-tyrosyl-L-tyrosine. Grade: 95%. CAS No. 1050-28-8. Molecular formula: C18H20N2O5. Mole weight: 344.36.
H-Tyr-val-oh
H-Tyr-val-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TYR-VAL;H-TYR-VAL-OH;L-TYROSYL-L-VALINE;TYR-VAL CRYSTALLINE;L-Tyr-L-Val-OH;N-L-Tyrosyl-L-valine;Tyr-Val-OH. Product Category: Heterocyclic Organic Compound. CAS No. 17355-09-8. Molecular formula: C14H20N2O4. Mole weight: 280.32. Product ID: ACM17355098. Alfa Chemistry ISO 9001:2015 Certified. Categories: Tyrosyl-Valine.
HU 308. Group: Biochemicals. Alternative Names: (1R, 4R, 5R)-rel-(+)-4-[4-(1, 1-dimethylheptyl)-2, 6-dimethoxyphenyl]-6, 6-dimethylbicyclo[3. 1. 1]hept-2-ene-2-methanol. Grades: Highly Purified. CAS No. 256934-39-1. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C27H42O3. US Biological Life Sciences.
Worldwide
Hu7691
Hu7691 is an orally active, selective Akt inhibitor with IC50s of 4.0 nM, 97.5 nM, 28 nM for Akt1, Akt2 and Akt3, respectively. It also inhibits tumor growth and enables decrease of cutaneous toxicity in mice. CAS No. 2360523-76-6. Molecular formula: C22H22ClF3N4O. Mole weight: 450.88.
Hu7691
Hu7691 is an orally active, selective Akt inhibitor with IC 50 s of 4.0 nM, 97.5 nM, 28 nM for Akt1, Akt2 and Akt3, respectively. Hu7691 inhibits tumor growth and enables decrease of cutaneous toxicity in mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2360523-76-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-132302.
Hu7691 free base
Hu7691 free base is an orally active, selective Akt inhibitor with IC50s of 4.0 nM, 97.5 nM, 28 nM for Akt1, Akt2 and Akt3, respectively. It also inhibits tumor growth and enables decrease of cutaneous toxicity in mice. CAS No. 2241232-43-7. Molecular formula: C22H21F3N4O. Mole weight: 414.42.
HuangjiangSuA
HuangjiangSuA. Group: Biochemicals. Grades: Plant Grade. CAS No. 1026020-27-8. Pack Sizes: 20mg. US Biological Life Sciences.
Worldwide
Huanglongmycin N
Huanglongmycin N is an inhibitor of DNA topoisomerase I with an EC50 of 14 μM. Synonyms: Huanglongmycin N; HY-N10115; CS-0256117. Molecular formula: C19H16O5. Mole weight: 324.33.
Hucker Ammonium Oxalate Crystal Violet, Laboratory Grade, 500 mL
Characteristic: dark violet liquid. Notes: For Gram staining. Contains crystal violet and ammonium oxalate. Storage Code: Red; flammable. Group: chem-category biological stains. Alternative Names: Crystal Violet Solution, Hucker's, Crystal violet Huckers stain. Grades: chem-grade laboratory. Product ID: 867485. -- SOLD FOR EDUCATIONAL USE ONLY --
HUHS015
HUHS015 is a potent PCA-1/ALKBH3 inhibitor both in vitro and in vivo. The bioavailability (BA) of HUHS015 was 7.2% in rats after oral administration. As expected, continuously administering HUHS015 significantly suppressed the growth of DU145 cells, which are human hormone-independent prostate cancer cells, in a mouse xenograft model without untoward effects. Synonyms: HUHS015; HUHS 015; HUHS-015. Grade: 0.98. CAS No. 1453097-13-6. Molecular formula: C19H18N4O. Mole weight: 318.37242.
HUHS015
HUHS015 is a potent prostate cancer antigen-1 (PCA-1/ALKBH3) inhibitor with an IC50 of 0.67?M for PCA-1[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1453097-13-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100199.