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| Product | Description | |
|---|---|---|
| H-Pro-Met-OH | H-Pro-Met-OH is used as an antihypertensive drug or health care product. Synonyms: L-Prolyl-L-methionine; Pro-Met; prolylmethionine; PM dipeptide; Proline Methionine dipeptide. Grade: >99%. CAS No. 52899-08-8. Molecular formula: C10H18N2O3S. Mole weight: 246.33. |  |
| H-Pro-NH2 | An impurity of Vildagliptin. Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. Synonyms: L-Prolinamide; (2S)-2-Pyrrolidinecarboxamide; (-)-Prolinamide; (2S)-2-Carbamoylpyrrolidine; (2S)-Pyrrolidine-2-carboxylic acid amide; (S)-2-(Aminocarbonyl)pyrrolidine; (S)-Prolinamide; (S)-Proline Amide; 2-Pyrrolidinecarboxamide, (2S)-; 2-Pyrrolidinecarboxamide, (S)-; Prolinamide, L-; (S)-Pyrrolidine-2-carboxamide; (S)-Pyrrolidine-2-carboxylic acid amide; L-Proline amide. Grade: ≥95%. CAS No. 7531-52-4. Molecular formula: C5H10N2O. Mole weight: 114.10. | |
| H-Pro-NH2 99.5+% (HPLC) | H-Pro-NH2 99.5+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g, 250g. US Biological Life Sciences. |  Worldwide |
| H-Pro-phe-arg-amc acetate salt | H-Pro-phe-arg-amc acetate salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Pro-phe-arg-mca, CID174085, Prolyl-phenylalanyl-arginine-4-methylcoumaryl-7-amide, L-Argininamide, L-prolyl-L-phenylalanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-, 65147-21-9. Product Category: Heterocyclic Organic Compound. CAS No. 65147-21-9. Molecular formula: C30H37N7O5. Mole weight: 575.67. Purity: 0.96. IUPACName: (2S)-N-[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-2-[(4-methyl-2-oxochromen-7-yl)amino]pentanoyl]amino]-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide. Density: 1.39g/cm³. Product ID: ACM65147219. Alfa Chemistry ISO 9001:2015 Certified. |  |
| H-Pro-phe-gly-lys-oh | H-Pro-phe-gly-lys-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-Pro-Phe-Gly-Lys-OH. Product Category: Heterocyclic Organic Compound. CAS No. 143547-77-7. Molecular formula: C22H33N5O5. Mole weight: 447.533. Product ID: ACM143547777. Alfa Chemistry ISO 9001:2015 Certified. | |
| H-Pro-pNA TFA | H-Pro-pNA TFA acts as a chromogenic substrate for prolyl aminopeptidase (proline iminopeptidase). Synonyms: L-Proline 4-nitroanilide trifluoroacetate; (S)-N-(4-Nitrophenyl)-2-pyrrolidinecarboxamide Mono(trifluoroacetate); (2S)-N-(4-Nitrophenyl)-2-pyrrolidinecarboxamide Mono(trifluoroacetate); H-L-Pro-pNA Trifluoracetate; H-Pro-Pna TFA; L-Proline p-nitroanilide trifluoroacetate salt; Pro-pNA; P-pNA; H Pro Pna TFA; 2-Pyrrolidinecarboxamide, N-(4-nitrophenyl)-, (2S)-, mono(trifluoroacetate); 2-Pyrrolidinecarboxamide, N-(4-nitrophenyl)-, (S)-, mono(trifluoroacetate); 2-Pyrrolidinecarboxamide, N-(4-nitrophenyl)-, (2S)-, 2,2,2-trifluoroacetate (1:1). Grade: ≥95%. CAS No. 108321-19-3. Molecular formula: C11H13N3O3.C2HO2F3. Mole weight: 349.26. | |
| H-Pro-pNA·TFA 99+% (HPLC) | H-Pro-pNA·TFA 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences. | Worldwide |
| H-Pro-Pro-Asp-NH2 | H-Pro-Pro-Asp-NH2, adsorbed on modified silica gel, is a highly efficient recyclable chiral catalyst for aldol reactions. Synonyms: H-PPD-NH2; L-prolyl-L-prolyl-L-isoasparagine; L-Prolyl-L-prolyl-L-α-asparagine; (S)-4-amino-4-oxo-3-((S)-1-((S)-pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamido)butanoic acid. Grade: ≥95%. CAS No. 850440-85-6. Molecular formula: C14H22N4O5. Mole weight: 326.35. | |
| H-Pro-Pro-Gln-OH | H-Pro-Pro-Gln-OH is an effective catalyst for conjugate addition reaction between aldehydes and β-substituted nitroolefins. Synonyms: H-PPQ-OH; L-prolyl-L-prolyl-L-glutamine; Prolyl-prolyl-glutamine; (S)-5-amino-5-oxo-2-((S)-1-((S)-pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamido)pentanoic acid. Grade: ≥95%. CAS No. 856170-98-4. Molecular formula: C15H24N4O5. Mole weight: 340.37. | |
| H-Pro-pro-gly-phe-ser-pro-oh | H-Pro-pro-gly-phe-ser-pro-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PRO-PRO-GLY-PHE-SER-PRO;BRADYKININ (2-7);H-PRO-PRO-GLY-PHE-SER-PRO-OH;L-PRO-PRO-GLY-PHE-SER-PRO;bradykinin fragment 2-7;L-Pro-L-Pro-Gly-L-Phe-L-Ser-L-Pro-OH;Pro-Pro-Gly-Phe-Ser-Pro-OH. Product Category: Heterocyclic Organic Compound. CAS No. 23828-06-0. Molecular formula: C29H40N6O8. Mole weight: 600.66. Product ID: ACM23828060. Alfa Chemistry ISO 9001:2015 Certified. | |
| H-Pro-pro-pro-pro-oh | H-Pro-pro-pro-pro-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: L-PRO-PRO-PRO-PRO;H-PRO-PRO-PRO-PRO-OH. Product Category: Heterocyclic Organic Compound. CAS No. 21866-90-0. Molecular formula: C20H30N4O5. Mole weight: 406.48. Product ID: ACM21866900. Alfa Chemistry ISO 9001:2015 Certified. | |
| H-PRO-PRO-PRO-PRO-OH | PPPP was used as an internal standard in the quantitative determination of the antihypertensive (ACE-inhibiting) peptides IPP and VPP in cheese by HPLC-MS3. Synonyms: L-Pro-Pro-Pro-Pro. CAS No. 21866-90-0. Molecular formula: C20H30N4O5. Mole weight: 406.48. | |
| H-Pro-Pro-Ser(OtBu)-NH2 | H-Pro-Pro-Ser(OtBu)-NH2 is a protected tripeptide used in peptide synthesis. The H indicates a free N-terminus on the proline (Pro) residue, allowing for further coupling or reactions. The sequence includes two proline residues, which are known for introducing structural kinks or turns in peptide chains. The hydroxyl group of the serine (Ser) residue is protected by an OtBu (tert-butyl) group, which prevents it from reacting until selective deprotection. The -NH2 at the C-terminus denotes a free amine group, enabling additional modifications or coupling reactions. This peptide is utilized to introduce proline and serine into peptide sequences while controlling functional group reactivity through selective protection. Synonyms: PPS; (S)-1-(L-Prolyl)-N-((S)-1-amino-3-(tert-butoxy)-1-oxopropan-2-yl)pyrrolidine-2-carboxamide; H-Pro-Pro-Ser(tBu)-NH2. Grade: ≥95%. Molecular formula: C17H30N4O4. Mole weight: 354.45. | |
| H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH | H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH, the p-nitrophenylalanine-containing substrate, is used for a convenient assay of pepsin and other aspartic proteinases of animal and microbial origin. It is soluble over a wide pH range with the Km values showing only little variation (Km = 80 μM at pH 3.1 and 37°C for porcine pepsin). Synonyms: L-prolyl-L-threonyl-L-alpha-glutamyl-L-phenylalanyl-4-nitro-L-phenylalanyl-L-arginyl-L-leucine; PTEF-Nph-RL; L-Pro-L-Thr-L-Glu-L-Phe-4-Nitro-L-Phe-L-Arg-L-Leu-OH; (2S,5S,8S,11S,14S)-11-benzyl-5-(3-guanidinopropyl)-14-((2S,3R)-3-hydroxy-2-((S)-pyrrolidine-2-carboxamido)butanamido)-2-isobutyl-8-(4-nitrobenzyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazaheptadecane-1,17-dioic acid; L-Leucine, N-(N2-(4-nitro-N-(N-(N-(N-L-prolyl-L-threonyl)-L-alpha-glutamyl)-L-phenylalanyl)-L-phenylalanyl)-L-arginyl)-, (2'E)-; L-Prolyl-L-threonyl-L-α-glutamyl-L-phenylalanyl-4-nitro-L-phenylalanyl-N5-(diaminomethylene)-L-ornithyl-L-leucine. Grade: ≥95%. CAS No. 90331-82-1. Molecular formula: C44H63N11O13. Mole weight: 954.04. | |
| H-Pro-thr-his-ile-lys-trp-gly-asp-oh | H-Pro-thr-his-ile-lys-trp-gly-asp-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-PRO-THR-HIS-ILE-LYS-TRP-GLY-ASP-OH;PRO-THR-HIS-ILE-LYS-TRP-GLY-ASP;tuna AI. Product Category: Heterocyclic Organic Compound. CAS No. 117620-76-5. Molecular formula: C44H64N12O12. Mole weight: 953.0522. Purity: 0.96. IUPACName: (2S)-2-[[2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S,3S)-2-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[(2S)-pyrrolidine-2-carbonyl]amino]butanoyl]amino]-3-(4H-imidazol-4-yl)propanoyl]amino]-3-methylpentanoyl]amino]hexanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]acetyl]amino]. Canonical SMILES: CCC(C)C(C(=O)NC(CCCCN)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NCC(=O)NC(CC(=O)O)C(=O)O)NC(=O)C(CC3=CN=CN3)NC(=O)C(C(C)O)NC(=O)C4CCCN4. Density: 1.49 g/cm³. Product ID: ACM117620765. Alfa Chemistry ISO 9001:2015 Certified. | |
| HPTDP | HPTDP. Synonyms: HPTDP; S-(1-Oxo-2-pyridyl)-thio-1,3-dimethylpropyleneuronium hexafluorophosphate; S-(1-Oxo-2-pyridyl)-thio-1,3-dimethylpropyleneuronium hexafluorophosphate; 1,3,5-Trimethyl-2-[(1-oxo-1lambda~5~-pyridin-2-yl)sulfanyl]-4,5-dihydro-1H-imidazol-3-ium hexafluorophosphate. Grade: 97% (HPLC). CAS No. 366821-62-7. Molecular formula: C11H16N3OS.PF6. Mole weight: 383.29. | |
| hPTHrP (1-36) | hPTHrP (1-36) has been shown to be one of the authentic secretory forms of PTHrP. Synonyms: Parathyroid hormone-related protein (1-36); Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-Glu-Ile. CAS No. 172867-62-8. Molecular formula: C191H305N59O52. Mole weight: 4260.10. | |
| HPTU | HPTU. Synonyms: HPTU; 1,1,3,3-Tetramethyl-2-(2-oxopyridin-1(2H)-yl)isouronium hexafluorophosphate; 1,1,3,3-Tetramethyl-2-(2-oxopyridin-1(2H)-yl)isouroniumhexafluorophosphate; AmbotzRL-1092; M-1123; O-(2-pyridone)-1,1,3,3-tetramethyluronium hexafluorophosphate; O-(1,2-dihydro-2-oxo-pyridyl)-N,N,N',N'-tetramethyluronium hexafluorophosphate. Grade: 95%. CAS No. 364047-51-8. Molecular formula: C10H16N3O2.F6P. Mole weight: 355.22. | |
| HPTU | HPTU. Group: Biochemicals. Alternative Names: 1,1,3,3-Tetramethyl-2-(2-oxopyridin-1(2H)-yl)isouronium hexafluorophosphate. Grades: Highly Purified. CAS No. 364047-51-8. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C10H16F6N3O2P. US Biological Life Sciences. | Worldwide |
| HPV16-E711-20 epitope | HPV16-E711-20 epitope is a known HLA-A*0201-restricted human cytotoxic T lymphocyte (CTL) epitope of HPV16-E7 protein, which binds to HLA-A2 with high affinity in vitro. Synonyms: H-Tyr-Met-Leu-Asp-Leu-Gln-Pro-Glu-Thr-Thr-OH; L-tyrosyl-L-methionyl-L-leucyl-L-alpha-aspartyl-L-leucyl-L-glutaminyl-L-prolyl-L-alpha-glutamyl-L-threonyl-L-threonine. Grade: ≥95%. CAS No. 160040-04-0. Molecular formula: C53H83N11O19S. Mole weight: 1210.35. | |
| HPV16 E7 86-93 | HPV16 E7 86-93 is a human leukocyte antigen (HLA)-A2-restricted HPV16 E7 derived peptide that has immunogenicity in cervical cancer. Synonyms: H-Thr-Leu-Gly-Ile-Val-Cys-Pro-Ile-OH; L-threonyl-L-leucyl-glycyl-L-isoleucyl-L-valyl-L-cysteinyl-L-prolyl-L-isoleucine. Grade: ≥95%. CAS No. 160212-93-1. Molecular formula: C37H66N8O10S. Mole weight: 815.03. | |
| HPV16 E7 (86-93) acetate | HPV16 E7 86-93 is a human leukocyte antigen (HLA)-A2-restricted HPV16 E7 derived peptide that has immunogenicity in cervical cancer. Synonyms: HPV16 E7 (86-93) acetate; AKOS040764039. Molecular formula: C39H70N8O12S. Mole weight: 875.08. | |
| H-Pyr-OBzl | H-Pyr-OBzl. Grade: ≥ 95%. Molecular formula: C12H13NO3. Mole weight: 219.2. | |
| H-Pyr-Oet HCl | H-Pyr-Oet HCl. Synonyms: ethyl (2S)-5-oxopyrrolidine-2-carboxylate hydrochloride. CAS No. 105210-68-2. Molecular formula: C7H11NO3·HCl. Mole weight: 193.7. | |
| HpySE526 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of pUC19 DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme about 95% of the dna fragments can be ligated with t4 dna ligase and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. A↑CGT TGC↓A. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: An E.coli strain, that carries the cloned HpySE 526I gene from Helicobacter pylori SE526. Pack: 10 mM Tris-HCl (pH 7.6); 100 mM NaCl; 0,1 mM EDTA; 200 μg/ml BSA; 1 mM DTT; and 50% glycerol. Cat No: ET-1123RE. |  |
| HQ-415 | HQ-415 is a relevant bioactive metal chelators(EC50=15 μM). Uses: A relevant bioactive metal chelators. Synonyms: 7-[(3-Ethoxy-4-methoxyphenyl)-[(4-methylpyridin-2-yl)amino]methyl]quinolin-8-ol; HQ-415; HQ 415; HQ415. Grade: ≥95%. CAS No. 430462-93-4. Molecular formula: C25H25N3O3. Mole weight: 415.48. | |
| HQ461 | HQ461 is a molecular glue that promotes CDK12-DDB1 interaction to trigger cyclin K degradation. HQ461-mediated degradation of cyclin K impairs CDK12 function, resulting in decreased CDK12 substrate phosphorylation, downregulation of DNA damage response genes, and cell death [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1226443-41-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144981. |  |
| HQ461 | HQ461 is a Molecular-glue degrader. HQ461 acts by promoting an interaction between CDK12 and DDB1-CUL4-RBX1 E3 ubiquitin ligase, leading to polyubiquitination and degradation of CDK12-interacting protein Cyclin K (CCNK). Degradation of CCNK mediated by HQ461 compromised CDK12 function, leading to reduced phosphorylation of a CDK12 substrate, downregulation of DNA damage response genes, and cell death. Structure-activity relationship analysis of HQ461 revealed the importance of a 5-methylthiazol-2-amine pharmacophore and resulted in an HQ461 derivate with improved potency. Uses: Designed for use in research and industrial production. Additional or Alternative Names: HQ461; HQ-461; HQ 461. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1226443-41-9. Molecular formula: C15H15N5OS2. Mole weight: 345.44. Purity: >98%. IUPACName: 2-(2-((6-methylpyridin-2-yl)amino)thiazol-4-yl)-N-(5-methylthiazol-2-yl)acetamide. Canonical SMILES: CC1C=CC=C(NC2=NC(CC(=O)NC3=NC=C(C)S3)=CS2)N=1. Product ID: ACM1226443419. Alfa Chemistry ISO 9001:2015 Certified. Categories: HQ-6. | |
| HQL 79 | HQL 79. Group: Biochemicals. Grades: Purified. CAS No. 162641-16-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| HQL 79 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| HQL 79 | HQL 79 is a selective inhibitor of human hematopoietic prostaglandin D synthase (H-PGDS) (IC50 = 6 μM). HQL 79 is potentially used as an antihistamine that exerts antiallergic and antiasthmatic properties in vivo. Synonyms: HQL-79; HQL 79; HQL79. 4-(Diphenylmethoxy)-1-(3-2H-tetrazol-5-yl)propyl]-piperidine; Cc-704. Grade: ≥99% by HPLC. CAS No. 162641-16-9. Molecular formula: C22H27N5O. Mole weight: 377.48. | |
| HQNO | It is produced by the strain of Pseudomonas pyocyanea, P. aeruginosa, P. methanica. HQNO is a quinolone inhibitor that blocks NADH oxidase (NADH) and Na+-dependent NADH-quinone reductase (NQR). It has weak anti-gram-positive bacterial activity. It can inhibit the microsomal respiratory chain and 5-lipoxygenase of cytochrome BC1 complex, and antagonize the antibacterial activity of dihydrostreptomycin. Synonyms: Antibiotic KF 8940; 2-Heptyl-1-hydroxy-4-(1H)-quinolinone; 2-heptyl-4-hydroxyquinoline n-oxide; HOQNO; 2-Heptyl-4-quinolinol 1-oxide; 2-heptylquinolin-4-ol 1-oxide; 2-(n-Heptyl)-4-hydroxyquinoline N-oxide. Grade: ≥98%. CAS No. 341-88-8. Molecular formula: C16H21NO2. Mole weight: 259.34. | |
| HQNO | HQNO, secreted by P. aeruginosa, is a potent electron transport chain inhibitor with a Kd of 64 nM for complex III[1]. HQNO is a potent inhibitor of mitochondrial NDH-2 in many species[2]. Uses: Scientific research. Group: Natural products. CAS No. 341-88-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-130055. | |
| H-(R)-beta-Tyr-OH | H-(R)-beta-Tyr-OH. Synonyms: D-β-Phe(4-OH)-OH; D-β-Tyr-OH; (R)-3-Amino-3-(4-hydroxyphenyl)propionic acid; (R)-3-AMINO-3-(4-HYDROXY-PHENYL)-PROPIONIC ACID; H-D-b-Phe(4-OH)-OH; H-PHG(4-OH)-(CCH2)OH; S-4-NO2-PHA. Grade: ≥ 99% (HPLC). CAS No. 73025-69-1. Molecular formula: C9H11NO3. Mole weight: 181.19. | |
| H-Resorcinol | Spectrophotometric reagent for the determination of B. Group: Uv/visible (uv/vis) spectroscopy. Alternative Names: 1-(2,4-Dihydroxy-1-phenylazo)-8-hydroxynaphthalene-3,6-disulfonic Acid Disodium Salt. | |
| HRO761 | HRO761 (Werner syndrome RecQ helicase-IN-1) (example 42) is a potent Werner syndrome RecQ DNA helicase enzyme ( WRN ) inhibitor and can be used in cancer research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Werner syndrome RecQ helicase-IN-1. CAS No. 2869954-34-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-148699. | |
| HRS-4642 | HRS-4642 is a selective KRAS(G12D) inhibitor (Kd=0.083 nM) with anti-cancer activity. HRS-4642 synergizes with Carfilzomib (HY-10455) and exhibits significant in vivo potency to reshape the tumor microenvironment into an immune-activating microenvironment. Uses: Scientific research. Group: Signaling pathways. CAS No. 2836263-09-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159127. | |
| HRV-3C Protease. | N-Terminal His tagged recombinant protein, aqueous solution, 0.8-1.2 mg/mL. Group: Fluorescence/luminescence spectroscopy. | |
| HRV3C Protease from human, Recombinant | Human rhinovirus 3C protease (HRV3C Protease) is a cysteine protease that recognizes the cleavage site of Leu-Glu-Val-Leu-Phe-Gln*Gly-Pro. It is supplied as a 47 kDa protein with both GST and Histidine tags for easy removal by His-Select or Glutathione agarose along with the cleaved tag. HRV3C Protease is capable of cleaving small peptides with the sequence of polyprotein processing sites. It cleaves after the glutamine residue. HRV cleavage site generally contains Gln/Gly scissile bond. Hrv3c protease is a recombinant restriction-grade cysteine protease. it folds into two topologically alike six-stranded β barrels. however, β barrels are different in length and ... with both gst and histidine tags for easy removal by his-select or glutathione agarose along with the cleaved tag. hrv3c protease has a therapeutic implication because of its unique protein structure. it may be used for the biochemical and structural characterization conducted on hrv 3c protease along with the development of 3c protease inhibitors. Group: Enzymes. Synonyms: HRV3C Protease; HRV3C; Human rhinovirus 3C protease. HRV3C. Activity: > 1 units/μg. Storage: -20°C. Form: Supplied as a solution in 25 mM Tris-HCl, pH 8.0, 50 mM NaCl, 1 mM TCEP and 50% glycerol. Source: E. coli. Species: Human. HRV3C Protease; HRV3C; Human rhinovirus 3C protease. Cat No: NATE-0345. | |
| HRX-0233 | HRX-0233 is a small-molecule MAP2K4 inhibitor. HRX-0233 results in strong tumor shrinkage without any apparent toxicity in H358 KRASG12C-mutant non-small cell lung cancers (NSCLC) in vivo. HRX-0233 efficiently prevents feedback activation of receptor tyrosine kinases (RTKs) upon monotherapy KRAS inhibitor Sotorasib (HY-114277) and causes a more sustained and complete inhibition of MAPK signaling. HRX-0233 is promising for research of AR-negative prostate cancer, lung and colon cancers[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2409140-12-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159190. | |
| HS 014 | HS 014. Group: Biochemicals. Grades: Purified. CAS No. 207678-81-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| HS 014 | HS 014 is a potent and selective melanocortin MC4 receptor antagonist (Ki = 3.16, 108, 54.4 and 694 nM for cloned human MC4, MC1, MC3 and MC5 receptors, respectively). HS 014 promotes food intake in rats and nociception in mice following central administration in vivo. HS 014 also inhibits IL-1β-induced Fos expression in the paraventricular hypothalamus. Synonyms: HS 014; HS014; HS-014. CAS No. 207678-81-7. Molecular formula: C71H94N20O17S2. Mole weight: 1563.77. | |
| HS 014 acetate | HS 014 acetate is a potent and selective melanocortin MC4 receptor antagonist with Kis of 3.16, 108, 54.4 and 694 nM for cloned human MC4, MC1, MC3 and MC5 receptors, respectively. HS 014 promotes food intake in rats and nociception in mice following central administration in vivo. HS 014 also inhibits IL-1β-induced Fos expression in the paraventricular hypothalamus. Synonyms: HS014 acetate; HS-014 acetate; Ac-Cys-Glu-His-D-2Nal-Arg-Trp-Gly-Cys-Pro-Pro-Lys-Asp-NH2.CH3CO2H (Disulfide bridge: Cys1-Cys8); N-acetyl-L-cysteinyl-L-alpha-glutamyl-L-histidyl-3-(2-naphthyl)-D-alanyl-L-arginyl-L-tryptophyl-glycyl-L-cysteinyl-L-prolyl-L-prolyl-L-lysyl-L-isoasparagine (1->8)-disulfide acetic acid. Grade: ≥95%. Molecular formula: C73H98N20O19S2. Mole weight: 1623.83. | |
| HS014 TFA | HS014 TFA is a potent and selective antagonist of melanocortin-4 (MC4) receptor, with Kis of 3.16, 108, 54.4 and 694 nM for human MC4, MC1, MC3 and MC5 receptors respectively. Grade: 98%. Molecular formula: C73H95F3N20O19S2. Mole weight: 1677.78. | |
| Hs024 | Hs024. Uses: Designed for use in research and industrial production. Additional or Alternative Names: HS024;(ACETYL-CYS3,NLE4,ARG5,D-2-NAL7,CYS11)-ALPHA-MSH (3-11) AMIDE TRIFLUOROACETATE SALT;AC-CYS-NLE-ARG-HIS-D-2-NAL-ARG-TRP-GLY-CYS-NH2;AC-CYS-NLE-ARG-HIS-D-2-NAL-ARG-TRP-GLY-CYS-NH2 TRIFLUOROACETATE SALT;AC-CYS-NLE-ARG-HIS-D-NAL(2)-ARG-TRP-GLY-CYS-NH2. Product Category: Heterocyclic Organic Compound. CAS No. 212370-59-7. Molecular formula: C58H81N19O10S2. Mole weight: 1268.52. Product ID: ACM212370597. Alfa Chemistry ISO 9001:2015 Certified. Categories: HS-24. | |
| HS 024 | HS 024. Group: Biochemicals. Grades: Purified. CAS No. 212370-59-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| HS 024 | HS 024 is a potent melanocortin MC4 receptor antagonist (Ki = 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors, respectively). HS 024 promotes food intake, blocks α-MSH- and MTII-induced hypotension and bradycardia in rats, following central administration in vivo. Synonyms: Acetyl-(Cys3,Nle4,Arg5,D-2-Nal7,Cys11)-α-MSH (3-11) amide; N-acetyl-L-cysteinyl-L-norleucyl-L-arginyl-L-histidyl-3-(2-naphthyl)-D-alanyl-L-arginyl-L-tryptophyl-glycyl-L-cysteinamide (1->9)-disulfide; Ac-Cys(1)-Nle-Arg-His-D-2Nal-Arg-Trp-Gly-Cys(1)-NH2; HS024; HS-024. Grade: ≥95%. CAS No. 212370-59-7. Molecular formula: C58H79N19O10S2. Mole weight: 1266.52. | |
| HS024 TFA | HS024 is a selective antagonist of MC4 receptor, with Kis of 0.29, 3.29, 5.45, 18.6 nM for MC4, MC5, MC3, and MC1, respectively. Grade: 99%. Molecular formula: C60H80F3N19O12S2. Mole weight: 1380.52. | |
| HS-10296 | HS-10296 is an EGFR tyrosine kinase inhibitor. Upon administration, HS-10296 binds to and inhibits EGFR T790M, a secondarily acquired resistance mutation, inhibits the tyrosine kinase activity of EGFR T790M, prevents EGFR T790M-mediated signaling and leads to cell death in EGFR T790M-expressing tumor cells. Synonyms: HS 10296; HS10296. CAS No. 1899921-05-1. Molecular formula: C30H35N7O2. Mole weight: 525.64. | |
| HS-10352 Impurity D | HS-10352 Impurity D is an impurity of HS-10352, a selective PI3Kα inhibitor with inhibitory effects on the proliferation of cancer tumor cell lines harboring PIK3CA mutations. Synonyms: (R)-2-((R)-3-Aminobutanamido)propanoic acid; H-bAla(3R-Me)-D-Ala-OH. CAS No. 2276229-34-4. Molecular formula: C7H14N2O3. Mole weight: 174.20. | |
| HS-131 | HS-131 is a near-infrared dye tethered Hsp90 inhibitor capable of detecting oncogene-driven breast cancers, including a variety of different human breast cancer molecular subtypes. Synonyms: 4-((E)-2-((2Z,4E)-3-(4-(21-((2-carbamoyl-5-(3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indazol-1-yl)phenyl)amino)-6,9,12,15,18-pentaoxa-2-azahenicosyl)phenyl)-5-(3,3-dimethyl-1-(4-sulfobutyl)-3H-indol-1-ium-2-yl)penta-2,4-dien-1-ylidene)-3,3-dimethylindolin-1-yl)butane-1-sulfonate; 3H-Indolium, 2-[(1E,3Z,5E)-3-[4-[21-[[2-(aminocarbonyl)-5-(4,5,6,7-tetrahydro-3,6,6-trimethyl-4-oxo-1H-indazol-1-yl)phenyl]amino]-6,9,12,15,18-pentaoxa-2-azaheneicos-1-yl]phenyl]-5-[1,3-dihydro-3,3-dimethyl-1-(4-sulfobutyl)-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-3,3-dimethyl-1-(4-sulfobutyl)-, inner. CAS No. 2084850-40-6. Molecular formula: C71H95N7O13S2. Mole weight: 1318.68. | |
| HS-1371 | HS-1371 is a novel RIP3 kinase inhibitor with IC50 value of 20.8 nM. It binds to RIP3 in an ATP-competitive and time-independent manner in vitro, and inhibits RIP3-mediated necroptosis via the suppression of RIP3 kinase activity. Synonyms: HS 1371; HS1371; 4-(4-Methylphenoxy)-7-(1-piperidin-4-ylpyrazol-4-yl)quinoline. CAS No. 2158197-70-5. Molecular formula: C24H24N4O. Mole weight: 384.47. | |
| HS148 | HS148 (compound 22) is a selective DAPK3 inhibitor with an K i value of 119 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1892595-16-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117364. | |
| HS-173 | HS-173 is a potent PI3Kα inhibitor with potential anticancer activity. HS-173 inhibited the PI3K signaling pathway, and showed anti-proliferative effects on cancer cells. Also, HS-173 induced cell cycle arrest at the G(2)/M phase and apoptosis. In addition, HS-173 decreased the expression HIF-1α and VEGF which play an important role in angiogenesis. This effect was confirmed by the suppression of tube formation and migration assay in vitro. Furthermore, HS-173 diminished blood vessel formation in the Matrigel plug assay in mice. Therefore, HS-173 is considered as a novel drug candidate to treat cancer patients. Uses: Designed for use in research and industrial production. Additional or Alternative Names: HS173; HS 173; HS-173. Product Category: Inhibitors. Appearance: White to off-white solid powder. CAS No. 1276110-06-5. Molecular formula: C21H18N4O4S. Mole weight: 422.46. Purity: >98%. IUPACName: ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate. Canonical SMILES: O=C(C1=CN=C2C=CC(C3=CC(NS(=O)(C4=CC=CC=C4)=O)=CN=C3)=CN21)OCC. Product ID: ACM1276110065. Alfa Chemistry ISO 9001:2015 Certified. Categories: HD 173416. | |
| HS-173 | HS-173 is a potent and selective PI3Kα inhibitor displaying anticancer activity. HS-173 was shown to induce apoptosis via arresting the cell cycle at the G2/M phase. It also decreases angiogenesis induced by VEGF. Synonyms: Ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate; HS173; HS 173; HS-173. Grade: 98%. CAS No. 1276110-06-5. Molecular formula: C21H18N4O4S. Mole weight: 422.459. | |
| HS-1793 | HS-1793 is a resveratrol analog. It downregulates the expression of hypoxia-induced HIF-1 and VEGF and inhibits tumor growth of human breast cancer cells in a nude mouse xenograft model. Synonyms: 4-(6-hydroxy-2-naphthyl)-1,3-benzenediol. Grade: >98%. CAS No. 927885-00-5. Molecular formula: C16H12O3. Mole weight: 252.26. | |
| HS-243 | HS-243 is a highly potent inhibitor of interleukin-1 receptor-associated kinase (IRAK). HS-243 specifically inhibits intracellular IRAKs without TAK1 inhibition. Synonyms: HS 243; HS243. CAS No. 848249-10-5. Molecular formula: C17H16N4O3. Mole weight: 324.33. | |
| HS-27 | HS-27 is a fluorescently linked Hsp90 inhibitor with diagnostic and therapeutic potential in triple-negative breast cancer. Grade: 98%. CAS No. 1562024-11-6. Molecular formula: C52H60N6O12S. Mole weight: 993.1. | |
| HS-27 | HS-27, a fluorescently-tethered Hsp90 inhibitor, assays surface Hsp90 expression on intact tissue specimens. HS-27 is made up of the core elements of SNX-5422, an Hsp90 inhibitor, tethered via a PEG linker to a fluorescein derivative (fluorescein isothiocyanate or FITC), that binds to ectopically expressed Hsp90. HS-27 has potential use in a see-and-treat paradigm in breast cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1562024-11-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130851. | |
| HS271 | HS271 is a selective, highly potent and orally active IRAK4 inhibitor (IC50 = 7.2 μM), with superior enzymatic and cellular activity, as well as excellent pharmacokinetic properties. Synonyms: 2-Pyridinecarboxamide, N-[2-[2-(dimethylamino)ethyl]-6-(1-hydroxy-1-methylethyl)-2H-indazol-5-yl]-6-(trifluoromethyl)-; N-{2-[2-(Dimethylamino)ethyl]-6-(2-hydroxy-2-propanyl)-2H-indazol-5-yl}-6-(trifluoromethyl)-2-pyridinecarboxamide. Grade: ≥95%. CAS No. 2410393-15-4. Molecular formula: C21H24F3N5O2. Mole weight: 435.44. | |
| HS-276 | HS-276 is an orally active, potent and highly selective TAK1 inhibitor, with a Ki of 2.5 nM. HS-276 shows significant inhibition of TAK1, CLK2, GCK, ULK2, MAP4K5, IRAK1, NUAK, CSNK1G2, CAMKK?-1, and MLK1, with IC50 values of 8.25, 29, 33, 63, 125, 264, 270, 810, 1280, and 5585 nM, respectively. HS-276 can be used for rheumatoid arthritis (RA) research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2767422-72-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147141. | |
| HS38 | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| HS 38 | HS 38 is an ATP-competitive inhibitor of DAPK (IC50 = 200 nM) and ZIPK (Kd = 280 nM). It also inhibits PIM3 kinase (IC50 = 200 nM) with no significant effect on Src or Abl kinases. HS 38 regulates programmed cell death and phosphorylation of non-muscle and smooth muscle myosin. Synonyms: HS 38; HS38; HS-38; 2-[[1-(3-Chlorophenyl)-4,5-dihydro-4-oxo-1H-pyrazolo[3,4-d]pyrimidin-6-yl]thio]propanamide. Grade: ≥98% by HPLC. CAS No. 1030203-81-6. Molecular formula: C14H12CIN5O2S. Mole weight: 349.8. | |
| HS666 hydrochloride | HS666 is a selective κ opioid receptor partial agonist that activates central κ receptors to produce potent antinociception, displaying pharmacological characteristics of a κ receptor analgesic with reduced liability for aversive effects correlating with its low efficacy in the β-arrestin2 signalling pathway. Synonyms: 3-(2-((Cyclopropylmethyl)(phenethyl)amino)ethyl)phenol hydrochloride. Grade: 99%. CAS No. 1409931-99-2. Molecular formula: C20H25NO.HCl. Mole weight: 331.88. | |
| HS-72 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Hs-AFP1 | HsAFP1 is a plant defensin isolated from the coral bell (Heuchera sanguinea), which has a broad-spectrum antifungal activity. Synonyms: Asp-Gly-Val-Lys-Leu-Cys(1)-Asp-Val-Pro-Ser-Gly-Thr-Trp-Ser-Gly-His-Cys(2)-Gly-Ser-Ser-Ser-Lys-Cys(3)-Ser-Gln-Gln-Cys(4)-Lys-Asp-Arg-Glu-His-Phe-Ala-Tyr-Gly-Gly-Ala-Cys(2)-His-Tyr-Gln-Phe-Pro-Ser-Val-Lys-Cys(3)-Phe-Cys(4)-Lys-Arg-Gln-Cys(1). | |
| HsAp | HsAp is an antibacterial peptide isolated from Heterometrus spinifer. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Ser-Gly-Thr-Ser-Glu-Lys-Glu-Arg-Glu-Ser-Gly-Arg-Leu-Leu-Gly-Val-Val-Lys-Arg-Leu-Ile-Val-Cys-Phe-Arg-Ser-Pro-Phe-Pro. Grade: 95.9%. | |
| HsAp2 | HsAp2 is an antibacterial peptide isolated from Heterometrus spinifer. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Ser-Gly-Thr-Ser-Glu-Lys-Glu-Arg-Glu-Ser-Glu-Arg-Leu-Leu-Gly-Val-Val-Asn-Pro-Leu-Ile-Lys-Cys-Phe-Arg-Ser-Pro-Cys-Pro. Grade: 97.8%. | |
| HsAp3 | HsAp3 is an antibacterial peptide isolated from Heterometrus spinifer. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Ser-Gly-Thr-Pro-Glu-Lys-Glu-Arg-Glu-Ser-Gly-Arg-Leu-Leu-Gly-Val-Val-Lys-Arg-Tyr-Ile-Val-Cys-Val-Arg-Asn-Pro-Cys-Pro. Grade: 95.9%. | |
| HsAp4 | HsAp4 is an antibacterial peptide isolated from Heterometrus spinifer. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Ser-Gly-Thr-Ser-Glu-Lys-Glu-Arg-Glu-Ser-Gly-Arg-Leu-Leu-Gly-Val-Val-Lys-Arg-Leu-Ile-Val-Gly-Phe-Arg-Ser-Pro-Phe-Arg. Grade: 95.5%. | |
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