A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
The Caspase-3 Inhibitor I, Cell-Permeable controls the biological activity of Caspase-3. This small molecule/inhibitor is primarily used for Cancer applications. Group: Fluorescence/luminescence spectroscopy.
InSolution Caspase-3 Inhibitor II
The Caspase-3 Inhibitor II controls the biological activity of Caspase-3. This small molecule/inhibitor is primarily used for Cancer applications. Group: Fluorescence/luminescence spectroscopy.
InSolution Caspase-8 Inhibitor II
The Caspase-8 Inhibitor II controls the biological activity of Caspase-8. This small molecule/inhibitor is primarily used for Cancer applications. Group: Fluorescence/luminescence spectroscopy.
InSolution Caspase-9 Inhibitor I
The Caspase-9 Inhibitor I controls the biological activity of Caspase-9. This small molecule/inhibitor is primarily used for Cancer applications. Group: Fluorescence/luminescence spectroscopy.
InSolution Caspase Inhibitor I
The Caspase Inhibitor I controls the biological activity of Caspase. This small molecule/inhibitor is primarily used for Cancer applications. Group: Fluorescence/luminescence spectroscopy.
InSolution Caspase Inhibitor VI
The Caspase Inhibitor VI, also referenced under CAS 161401-82-7, controls the biological activity of Caspase. This small molecule/inhibitor is primarily used for Cancer applications. Group: Fluorescence/luminescence spectroscopy.
InSolution Cdk1 Inhibitor IV, RO-3306
The Cdk1 Inhibitor IV, RO-3306 controls the biological activity of Cdk1. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
The cFMS Receptor Tyrosine Kinase Inhibitor controls the biological activity of cFMS Receptor Tyrosine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
InSolution Epoxomicin, Synthetic
Epoxomicin, Synthetic, is a 1 mM solution of Epoxomicin, Synthetic (Cat. No. 324800) in DMSO. Group: Fluorescence/luminescence spectroscopy.
InSolution ERK Inhibitor II, FR180204
The ERK Inhibitor II, FR180204, also referenced under CAS 865362-74-9, controls the biological activity of ERK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
InSolution GM 6001
GM 6001, CAS 142880-36-2, is a 10 mM (1 mg/257 μl) solution of GM6001 in DMSO. A potent, cell-permeable, broad-spectrum inhibitor of MMPs. Group: Fluorescence/luminescence spectroscopy.
InSolution GSK-3 Inhibitor IX - CAS 667463-62-9
The GSK-3 Inhibitor IX, also referenced under CAS 667463-62-9, controls the biological activity of GSK-3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
InSolution GSK-3 Inhibitor XVI, CHIR99021 - CAS 252917-06-9
GSK-3 Inhibitor XVI, CHIR99021, CAS 252917-06-9, is a 25 mM solution in DMSO. A cell-permeable, ATP-competitive inhibitor of GSK-3 (IC?? = 10 & 6.7 nM for GSK-3? and GSK-3?, respectively). Group: Fluorescence/luminescence spectroscopy.
InSolution H-89, Dihydrochloride
H-89, Dihydrochloride, CAS 127243-85-0, is a 10 mM solution of H-89, 2HCl in DMSO. A cell-permeable, potent, reversible, ATP-competitive inhibitor of protein kinase A (Ki = 48 nM). Group: Fluorescence/luminescence spectroscopy.
InSolution JAK Inhibitor I - CAS 457081-03-7
The JAK Inhibitor I, also referenced under CAS 457081-03-7, controls the biological activity of JAK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
InSolution JNK Inhibitor II
The JNK Inhibitor II, also referenced under CAS 129-56-6, controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
InSolution Leptomycin B, Streptomyces sp. - CAS 87081-35-4
An antifungal antibiotic that acts as an inhibitor of nuclear export because of its ability to interact with and impair the function of the nuclear export factor CRM1. Group: Fluorescence/luminescence spectroscopy.
InSolution LY 294002 - CAS 154447-36-6
LY 294002, CAS 154447-36-6, is a 10 mM solution of LY 294002 (Cat. No. 440202) in DMSO. A cell-permeable, potent, reversible and specific inhibitor of PI 3-kinase (IC50 = 1.4 μM). Group: Fluorescence/luminescence spectroscopy.
InSolution MEK1/2 Inhibitor III, PD0325901 - CAS 391210-10-9
The MEK1/2 Inhibitor III, PD0325901, also referenced under CAS 391210-10-9, controls the biological activity of MEK1/2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
InSolution MG-132 - CAS 133407-82-6
MG-132, CAS 133407-82-6, is provided as a 10 mM solution in DMSO. Acts as a potent, reversible proteasome inhibitor (Ki = 4 nM). Group: Fluorescence/luminescence spectroscopy.
InSolution MG-132 in EtOH, ?95% by HPLC
Potent, reversible, and cell-permeable proteasome inhibitor. Reduces the degradation of ubiquitin-conjugated proteins in mammalian cells and permeable stains of yeast by the 26S complex. Group: Fluorescence/luminescence spectroscopy.
InSolution p38 MAP Kinase Inhibitor III
The p38 MAP Kinase Inhibitor III controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
InSolution PARP Inhibitor VIII, PJ34
The PARP Inhibitor VIII, PJ34 controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications. Group: Fluorescence/luminescence spectroscopy.
InSolution PD 98059 - CAS 167869-21-8
PD 98059, CAS 167869-21-8, is a 5 mg/ml solution in DMSO. A a cell-permeable, selective & reversible inhibitor of MAP Kinase Kinase (MEK). Group: Fluorescence/luminescence spectroscopy.
InSolution PKR Inhibitor - CAS 608512-97-6
The PKR Inhibitor, also referenced under CAS 608512-97-6, controls the biological activity of PKR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
InSolution PP1 Analog - CAS 221243-82-9
A potent, reversible, ATP-competitive, and cell-permeable inhibitor of Src-family tyrosine kinases that is >800 times more selective for the I338G mutant v-Src compared to wild-type v-Src. Group: Fluorescence/luminescence spectroscopy.
InSolution PP2
PP2, 172889-27-9, is a 10 mM solution of PP2 (Cat. No. 529573) in DMSO. A potent, reversible, ATP-competitive, inhibitor of the Src family of protein tyrosine kinases. Group: Fluorescence/luminescence spectroscopy.
InSolution Q-VD-OPh, Non-O-methylated
Q-VD-OPh, Non-O-methylated, is a cell-permeable, irreversible, broad-spectrum inhibitor of caspases (IC?? = 50, 100, 430, and <25 nM for caspase-1,-8, -9, and -3, respectively). Group: Fluorescence/luminescence spectroscopy.
InSolution Raf1 Kinase Inhibitor I
The Raf1 Kinase Inhibitor I controls the biological activity of Raf1. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
InSolution Rapamycin
Rapamycin, CAS 53123-88-9, is a 5 mM (500 μg/109 μl) solution of Rapamycin (Cat. No. 553210) in DMSO. Selectively inhibits mTOR and blocks activation of p70 S6 Kinase (IC?? = 50 pM). Group: Fluorescence/luminescence spectroscopy.
InSolution Rapamycin in EtOH
The Rapamycin, also referenced under CAS 53123-88-9, controls the biological activity of mTOR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
InSolution Ratjadone A, Synthetic - CAS 163564-92-9
A cell-permeable polyketide that displays potent antitumor properties in eukaryotes. Group: Fluorescence/luminescence spectroscopy.
InSolution RNA Polymerase III Inhibitor - CAS 577784-91-9
The RNA Polymerase III Inhibitor, also referenced under CAS 577784-91-9, controls the biological activity of RNA Polymerase III. This small molecule/inhibitor is primarily used for Cell Structure applications. Group: Fluorescence/luminescence spectroscopy.
InSolution SB 203580
InSolution SB 203580, CAS 152121-47-6, is a 1 mg/ml solution of SB 203580 in DMSO. A cell-permeable, selective, reversible inhibitor of p38 MAP kinase (IC?? = 34 nM in vitro, 600 nM in cells). Group: Fluorescence/luminescence spectroscopy.
InSolution Smoothened Agonist, SAG
Smoothened Agonist, SAG, is a 10 mM (500 μg/86 μl) solution of Smoothened Agonist, SAG (Cat. No. 566660) in H?O. Group: Fluorescence/luminescence spectroscopy.
InSolution Src Inhibitor, PP1
The Src Inhibitor, PP1 controls the biological activity of Src. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
InSolution TAPI-1
TAPI-1, CAS 171235-71-5, is a 10 mM solution of TAPI-1 in DMSO. A structural analog of TAPI-0 (Cat. No. 579050) with similar in vitro efficacy for the inhibition of MMPs and TACE. Group: Fluorescence/luminescence spectroscopy.
InSolution U0126 - CAS 109511-58-2
A potent and specific inhibitor of MEK1 and MEK2. Group: Fluorescence/luminescence spectroscopy.
InSolution Wortmannin
Wortmannin is a fungal metabolite that acts as a potent, selective, cell-permeable and irreversible inhibitor of phosphatidylinositol 3-kinase (PI 3-kinase). Group: Fluorescence/luminescence spectroscopy.
InSolution Y-27632
Y-27632A, CAS 146986-50-7, is a cell-permeable, reversible, inhibitor of Rho kinases (Ki = 140 nM for p160ROCK). Enhances survival & cloning efficiency of ESC without affecting their pluripotency. Group: Fluorescence/luminescence spectroscopy.
InSolution Y-27632 in DMSO
Y-27632 is a 10 mM solution in DMSO. A highly potent, cell-permeable, reversible, and selective inhibitor of Rho-associated protein kinases (Ki = 140 nM for p160ROCK). Group: Fluorescence/luminescence spectroscopy.
InSolution Y-27632 in DMSO
Y-27632 is a 10 mM solution in DMSO. A highly potent, cell-permeable, reversible, and selective inhibitor of Rho-associated protein kinases (Ki = 140 nM for p160ROCK). Uses: For analytical and research use. Group: Fluorescence/luminescence spectroscopy. Pack Sizes: 1MG. Mole weight: 247.34. Catalog: IAR42415742. Assay: ?95% (HPLC).
Insulin is a pancreatic hormone that regulates glucose metabolism, cellular uptake, as well as the storage of glucose, amino acids and fatty acids. It inhibits the production of endogenous glucose and the breakdown of glycogen. Uses: Hypoglycemic agents. Synonyms: Insulin recombinant; Endopancrine; Decurvon; Dermulin; Exubera. CAS No. 9004-10-8. Molecular formula: C256H381N65O77S6. Mole weight: 5793.602.
insulinase
Transferred to EC 3.4.24.56. Group: Enzymes. Enzyme Commission Number: EC 3.4.99.10. CAS No. 9013-83-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4376; insulinase; EC 3.4.99.10; 9013-83-6. Cat No: EXWM-4376.
Insulin aspart
Insulin aspart is an insulin analog that functions faster and lasts for a shorter time than regular insulin. Insulin aspart has been indicated for the treatment of type 1 and type 2 diabetes. Synonyms: DL-phenylalanyl-DL-valyl-DL-asparagyl-DL-glutaminyl-DL-histidyl-DL-leucyl-DL-cysteinyl-glycyl-DL-seryl-DL-histidyl-DL-leucyl-DL-valyl-DL-alpha-glutamyl-DL-alanyl-DL-leucyl-DL-tyrosyl-DL-leucyl-DL-valyl-DL-cysteinyl-glycyl-DL-alpha-glutamyl-DL-arginyl-glycyl-DL-phenylalanyl-DL-phenylalanyl-DL-tyrosyl-DL-threonyl-DL-alpha-aspartyl-DL-lysyl-DL-threonine (7->7'),(19->20')-bis(disulfide) compound with glycyl-DL-isoleucyl-DL-valyl-DL-alpha-glutamyl-DL-glutaminyl-DL-cysteinyl-DL-cysteinyl-DL-threonyl-DL-seryl-DL-isoleucyl-DL-cysteinyl-DL-seryl-DL-leucyl-DL-tyrosyl-DL-glutaminyl-DL-leucyl-DL-alpha-glutamyl-DL-asparagyl-DL-tyrosyl-DL-cysteinyl-DL-asparagine (6'->11')-disulfide; H-DL-Phe-DL-Val-DL-Asn-DL-Gln-DL-His-DL-Leu-DL-Cys(1)-Gly-DL-Ser-DL-His-DL-Leu-DL-Val-DL-Glu-DL-Ala-DL-Leu-DL-Tyr-DL-Leu-DL-Val-DL-Cys(2)-Gly-DL-Glu-DL-Arg-Gly-DL-Phe-DL-Phe-DL-Tyr-DL-xiThr-DL-Asp-DL-Lys-DL-xiThr-OH.H-Gly-DL-xiIle-DL-Val-DL-Glu-DL-Gln-DL-Cys(3)-DL-Cys(1)-DL-xiThr-DL-Ser-DL-xiIle-DL-Cys(3)-DL-Ser-DL-Leu-DL-Tyr-DL-Gln-DL-Leu-DL-Glu-DL-Asn-DL-Tyr-DL-Cys(2)-DL-Asn-OH. CAS No. 116094-23-6. Molecular formula: C256H381N65O79S6. Mole weight: 5825.53.
Insulin aspart
Insulin aspart (B28Asp) is a fast-acting analog of human insulin. Insulin aspart provides more rapid absorption than regular human insulin after subcutaneous administration. Insulin aspart can be used for researching diabetes [1]. Uses: Scientific research. Group: Peptides. Alternative Names: B28Asp; B28-Asp-insulin; INA-X 14; Insulin X 14. CAS No. 116094-23-6. Pack Sizes: 100 U; 300 U. Product ID: HY-108767.
Insulin Aspart EP/USP
antagonist of histamine H1 and platelet-activating factor receptors. Grades: EP/USP. CAS No. 116094-23-6. Product ID: 8-04757. Molecular formula: C256H381N65O79S6. Mole weight: 5825.59.
Insulin (Beef)
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Insulin (cattle)
Insulin (cattle) is a polypeptide hormone that regulates glucose metabolism in pancreatic islet B cells. Synonyms: Insulin from bovine pancreas; Phe-Val-Asn-Gln-His-Leu-Cys-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Ala. Gly-Ile-Val-Glu-Gln-Cys-Cys-Ala-Ser-Val-Cys-Ser-Leu-Tyr-Gln-Leu-Glu-Asn-Tyr-Cys-Asn (Disulfide bridge: Cys7-Cys7', Cys19-Cys20', Cys6'-Cys11'). Grades: ≥97%. CAS No. 11070-73-8. Molecular formula: C254H377N65O75S6. Mole weight: 5733.49.
Insulin(cattle)
Insulin cattle is a two-chain polypeptide hormone produced in vivo in the pancreatic β cells. Insulin cattle has often been used as growth supplement in culturing cells. Uses: Scientific research. Group: Peptides. CAS No. 11070-73-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1156.
Insulin degludec
Insulin degludec is an ultra-long-acting form of insulin used for the research of hyperglycemia caused by type 1 and type 2 dabetes. Insulin degludec shows binding efficiency with an IC 50 value of 19.59 nM for insulin receptor. Insulin degludec can be used for the research of type 1 and type 2 diabetes [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 844439-96-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108743.
Insulin Degludec
Insulin Degludec. CAS No. 844439-96-9. Product ID: 2-08522. Molecular formula: C274H411N65O81S6. Mole weight: 6103.98. Source : long-lasting insulin analog modifed with hexadecanedioic acid via gamma-L-glutamyl spacer at B29 Lysine.
Insulin Degrading Enzyme (HisoTag) from Rat, Recombinant
Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over sixty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently. This discovery revealed considerable amino acid sequence similarity between IDE and the previously characterized bacterial protease pitrilysin, suggesting a common proteolytic mechanism. Recombinant, rat insulin degrading enzyme fused to a hisotag sequence and expressed in s. frugiperda insect cells. a metalloprotease that degrades insulin and a variety of other peptides including amyloid peptides. Group: Enzymes. Synonyms: IDE; Insulin-degrading enzyme; insulysin; insulin protease. Enzyme Commission Number: EC 3.4.24.56. Purity: >90% by SDS-PAGE. IDE. Mole weight: 110 kDa. Activity: >3 U/mg protein. Storage: < -70°C. Form: Liquid. Source: S. frugiperda. Species: Rat. IDE; Insulin-degrading enzyme; insulysin; insulin protease. Cat No: NATE-0849.
Insulin Detemir
Insulin Detemir is an artificial insulin, shows effect on controlling blood sugar levels. Insulin Detemir stimulates GLP-1 secretion as a consequence of enhanced Gcg expression by a mechanism involving activation of Akt - and/or extracellular signal-regulated kinase ( ERK )-dependent-cat and CREB signaling pathways. Insulin Detemir can be used for type 2 diabetes research [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 169148-63-4. Pack Sizes: 100 U; 300 U. Product ID: HY-109556.
Insulin efsitora alfa
Insulin efsitora alfa (LY-3209590) is a selective agonist of insulin receptor (IR). Insulin efsitora alfa is a fusion protein composed of human IR agonists fused with the crystallizable (Fc) domain of human immunoglobulin G2 (IgG2) fragment, with a molecular weight of 64.1 kDa. Insulin efsitora alfa is well tolerated and has potential applications in diabetes [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LY-3209590. CAS No. 2131038-11-2. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P99665.
Insulin glargine is a long-acting insulin analog. Insulin glargine has the effect of lowering blood sugar and can be used in the research of diabetes. In addition, high doses of Insulin glargine can promote the proliferation of bladder cancer cells [1] [2] [3] [4]. Uses: Scientific research. Group: Peptides. CAS No. 160337-95-1. Pack Sizes: 100 U; 300 U. Product ID: HY-108719.
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Insulin Glargine Metabolite M1
a metabolite of Insulin Glargine. Grades: > 95%. Mole weight: 5750.64.
Insulin Glargine Metabolite M2
a metabolite of Insulin Glargine. Grades: > 95%. Mole weight: 5649.53.
Insulin glulisine
Insulin glulisine (HMR 1964) is a rapid-acting insulin analogue, it mimics the pharmacokinetic and pharmacodynamic profiles of physiological human insulin. Insulin glulisine can be used for the research of diabetes [1]. Uses: Scientific research. Group: Peptides. Alternative Names: HMR 1964. CAS No. 207748-29-6. Pack Sizes: 100 U. Product ID: HY-109555.
Insulin human
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Insulin (human)
Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. Its molecular weight is ~5800 Da. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat. Uses: Api. Synonyms: Recombinant human insulin; Insulin human; H-Phe-Val-Asn-Gln-His-Leu-Cys(1)-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys(2)-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Thr-OH.H-Gly-Ile-Val-Glu-Gln-Cys(3)-Cys(1)-Thr-Ser-Ile-Cys(3)-Ser-Leu-Tyr-Gln-Leu-Glu-Asn-Tyr-Cys(2)-Asn-OH; L-phenylalanyl-L-valyl-L-asparagyl-L-glutaminyl-L-histidyl-L-leucyl-L-cysteinyl-glycyl-L-seryl-L-histidyl-L-leucyl-L-valyl-L-alpha-glutamyl-L-alanyl-L-leucyl-L-tyrosyl-L-leucyl-L-valyl-L-cysteinyl-glycyl-L-alpha-glutamyl-L-arginyl-glycyl-L-phenylalanyl-L-phenylalanyl-L-tyrosyl-L-threonyl-L-prolyl-L-lysyl-L-threonine (7->7'),(19->20')-bis(disulfide) compound with glycyl-L-isoleucyl-L-valyl-L-alpha-glutamyl-L-glutaminyl-L-cysteinyl-L-cysteinyl-L-threonyl-L-seryl-L-isoleucyl-L-cysteinyl-L-seryl-L-leucyl-L-tyrosyl-L-glutaminyl-L-leucyl-L-alpha-glutamyl-L-asparagyl-L-tyrosyl-L-cysteinyl-L-asparagine (6'->11')-disulfide. Grades: ≥99% by HPLC. CAS No. 11061-68-0. Molecular formula: C257H383N65O77S6. Mole weight: 5807.57.
Insulin (human)
Insulin (human) is a polypeptide hormone that regulates the level of glucose. Insulin (human) can be used for the diabetes mellitus [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 11061-68-0. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0035.
Insulin (Human)
Insulin (Human) is a peptide hormone regulating the metabolism of carbohydrates and fats. It is used in the treatment of those suffering from the diabetes type I and II metabolic disorders. Regulates the absorption of glucose from the blood to skeletal muscles and fat storage. Group: Biochemicals. Grades: Highly Purified. CAS No. 11061-68-0. Pack Sizes: 5mg, 10mg. Molecular Formula: C257H383N65O77S6. US Biological Life Sciences.