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An impurity of Losartan, an angiotensin II receptor blocker (ARB) used to treat high blood pressure. Synonyms: 5-(4'-Methyl-2-biphenyl)tetrazole; 5-(4'-Methyl[1,1'-biphenyl]-2-yl)-2H-tetrazole; 2-(Tetrazol-5-yl)-4'-methyl-1,1'-biphenyl; 5-[2-(4'-Methylbiphenyl)]tetrazole; L 158507. Grades: > 95%. CAS No. 120568-11-8. Molecular formula: C14H12N4. Mole weight: 236.27.
Losartan Impurity F
Losartan Isopropyl Ether is an impurity of Losartan, a nonpeptide angiotensin II AT1-receptor antagonist and antihypertensive. Synonyms: Losartan Isopropyl Ether; 5-[4'-[[2-Butyl-4-chloro-5-[(1-methylethoxy)methyl]-1H-imidazol-1-yl]methyl][1,1'-biphenyl]-2-yl]-2H-tetrazole. Grades: > 95%. CAS No. 1332713-64-0. Molecular formula: C25H29ClN6O. Mole weight: 464.99.
Losartan Impurity G. Uses: For analytical and research use. Group: Impurity standards. CAS No. 165276-38-0. Molecular Formula: C22H21ClN6. Mole Weight: 404.9. Catalog: APB165276380.
Losartan Impurity J
O-Acetyl Losartan is a potential impurity of Losartan. Synonyms: O-Acetyl Losartan; 2-Butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol 5-Acetate. Grades: > 95%. CAS No. 1006062-27-6. Molecular formula: C24H25ClN6O2. Mole weight: 464.95.
N1-Losartanyl-losartan is an impurity found in Losartan tablets. Synonyms: N1-Losartanyl-losartan; 2-Butyl-1-[[2'-[1-[[2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazol-5-yl]methyl]-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-4-chloro-1H-imidazole-5-methanol. Grades: > 95%. CAS No. 230971-71-8. Molecular formula: C44H44Cl2N12O. Mole weight: 827.81.
Losartan Impurity M
N2-Losartanyl-losartan is an impurity found in Losartan tablets. Synonyms: N2-Losartanyl-losartan; 2-Butyl-1-[[2'-[2-[[2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazol-5-yl]methyl]-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-4-chloro-1H-imidazole-5-methanol. Grades: > 95%. CAS No. 230971-72-9. Molecular formula: C44H44Cl2N12O. Mole weight: 827.81.
Losartan Isomer Impurity, Potassium Salt
Losartan Isomer Impurity, Potassium Salt. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS002161. Format: Neat.
Losartan Isomer Impurity, Potassium Salt
Losartan impurity. Group: Biochemicals. Alternative Names: 2-Butyl-5-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-4-methanol Potassium Salt. Grades: Highly Purified. CAS No. 860644-28-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Losartan Isomer N2-Trityl Impurity
Losartan Isomer N2-Trityl Impurity. Uses: For analytical and research use. Group: Impurity standards. CAS No. 150098-04-7. Molecular Formula: C41H37ClN6O. Mole Weight: 665.24. Catalog: APB150098047.
Losartan Isopropyl Ether
Losartan Isopropyl Ether. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-[4'[[2-Butyl-4-chloro-5-[[(1-methylethyl)oxy]methyl]-1H-imidazol-1-yl]methyl]biphenyl-2-yl]-1H-tetrazole,Losartan Potassium Imp. F (EP) , Losartan Imp. F (EP) , Losartan Isopropyl Ether. CAS No. 1332713-64-0. IUPAC Name: 5-[2-[4-[[2-butyl-4-chloro-5-(isopropoxymethyl)imidazol-1-yl]methyl]phenyl]phenyl]-1H-tetrazole. Molecular Formula: C25H29ClN6O. Mole Weight: 464.992. Catalog: APS1332713640. SMILES: CCCCc1nc (Cl)c (COC (C)C)n1Cc2ccc (cc2)c3ccccc3c4nnn[nH]4. Format: Neat.
Losartan N1-Glucuronide is a metabolite of Losartan. Synonyms: 1-[5-[4-[[2-Butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl][1,1-biphenyl]-2-yl]-1H-tetrazol-1-yl]-1-deoxy-b-D-glucopyranuronic acid. Grades: > 95%. CAS No. 138584-34-6. Molecular formula: C28H31ClN6O7. Mole weight: 599.03.
Losartan N2-Glucuronide
Losartan N2-Glucuronide is a metabolite of Losartan. Synonyms: 1-[5-[4'-[[2-Butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl][1,1'-biphenyl]-2-yl]-2H-tetrazol-2-yl]-1-deoxy-β-D-Glucopyranuronic Acid; L 158783. Grades: > 95%. CAS No. 138584-35-7. Molecular formula: C28H31ClN6O7. Mole weight: 599.03.
Losartan N2-Glucuronide
Losartan N2-Glucuronide. Uses: For analytical and research use. Group: Impurity standards. CAS No. 138584-35-7. Molecular Formula: C28H31ClN6O7. Mole Weight: 599.04. Catalog: APB138584357.
Losartan N,O-Ditrityl Impurity
Losartan N,O-Ditrityl Impurity. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1796930-34-1. Molecular Formula: C60H51ClN6O. Mole Weight: 907.56. Catalog: APB1796930341.
Losartan N-Trithyl Impurity
Losartan N-Trithyl Impurity. Uses: For analytical and research use. Group: Impurity standards. CAS No. 124751-00-4. Molecular Formula: C41H37ClN6O. Mole Weight: 665.24. Catalog: APB124751004.
Losartan potassium
Heterocyclic Organic Compound. Alternative Names: Llosartan. CAS No. 12475-99-8. Molecular formula: C22H22ClKN6O. Catalog: ACM12475998.
Losartan potassium
Losartan potassium. Group: Biochemicals. Grades: Purified. CAS No. 124750-99-8. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Losartan potassium
Losartan potassium (DuP-753 potassium) is an angiotensin II receptor type 1 (AT1) antagonist, competing with the binding of angiotensin II to AT1 with an IC 50 of 20 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DuP-753 potassium. CAS No. 124750-99-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-17512A.
Losartan potassium salt
5g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C22H22ClKN6O. CAS No. 124750-99-8. Prepack ID 57826018-5g. Molecular Weight 461. See USA prepack pricing.
Losartan potassium salt
Losartan potassium salt. Group: Biochemicals. Alternative Names: 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol potassium salt; Cozaar; MK-954. Grades: Highly Purified. CAS No. 124750-99-8. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C22H22ClKN6O. US Biological Life Sciences.
Worldwide
Losartan Potassium Salt
Losartan is an angiotensin II receptor antagonist that competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM. It promotes vasodilatation and counteracts the effects of aldosterone thus can be used as an antihypertensive. Uses: Antihypertensive. Synonyms: MK 954; MK954; MK-954; Cozaar; Lorzaar; Losaprex; Hyzaar; [2-butyl-5-chloro-3-[[4-[2-(1,2,3-triaza-4-azanidacyclopenta-2,5-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol. Grades: >98%. CAS No. 124750-99-8. Molecular formula: C22H23ClKN6O. Mole weight: 462.01.
Losartan, Potassium Salt (Cozaar, MK-954, 2-Butyl-4-chloro-1-[[2-(1H-tetrazol-5yl)[1,1-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol)
A nonpeptide angiotensin II AT1-receptor antagonist. Group: Biochemicals. Alternative Names: Cozaar, MK-954, 2-Butyl-4-chloro-1-[[2-(1H-tetrazol-5yl)[1,1-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Losartan (potassium) (Standard)
Losartan (potassium) (Standard) is the analytical standard of Losartan (potassium). This product is intended for research and analytical applications. Losartan potassium (DuP-753 potassium) is an angiotensin II receptor type 1 (AT1) antagonist, competing with the binding of angiotensin II to AT1 with an IC 50 of 20 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DuP-753 (potassium) (Standard). CAS No. 124750-99-8. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-17512AR.
Losartan Related Compound A
Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan carboxaldehyde is a derivative of Losartan carboxaldehyde. Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan carboxaldehyde is also used as reagent to synthesize Losartan Potassium, an angiotensin II antagonist and is c. Synonyms: Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde; 4'-[(2-Butyl-4-chloro-5-formyl-1H-imidazol-1-yl)methyl]-[1,1'-Biphenyl]-2-carbonitrile; 4'-(2-Butyl-4-chloro-5-formylimidazol-1-ylmethyl)biphenyl-2-carbonitrile. Grades: > 95%. CAS No. 124750-67-0. Molecular formula: C22H20ClN3O. Mole weight: 377.87.
Losartan Related Compound B
Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan is a derivative of Losartan Potassium, an angiotensin II antagonist and is commonly used to significantly reduce risk of new onset atrial fibrillation and associated stroke in high-risk patients. Synonyms: Des[2'-(1H-tetrazol-5-yl)] 2-Cyanolosartan; 4'-[[2-Butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl]-[1,1'-biphenyl]-2-carbonitrile; 2-Butyl-4-chloro-1-[(2'-cyanobiphenyl-4-yl)methyl]-5-hydroxymethylimidazole; 4'-(2-Butyl-4-chloro-5-hydroxymethyl-. Grades: > 95%. CAS No. 114772-55-3. Molecular formula: C22H22ClN3O. Mole weight: 379.88.
Losartan Trityl Ether. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1006062-28-7. IUPAC Name: 5-[2-[4-[[2-butyl-5-chloro-4-(trityloxymethyl)imidazol-1-yl]methyl]phenyl]phenyl]-1H-tetrazole. Molecular Formula: C41H37ClN6O. Mole Weight: 665.23. Catalog: APS1006062287. SMILES: CCCCc1nc (COC (c2ccccc2) (c3ccccc3)c4ccccc4)c (Cl)n1Cc5ccc (cc5)c6ccccc6c7nnn[nH]7. Format: Neat.
Losartan Trityl Ether
Losartan Impurity D. Group: Biochemicals. Alternative Names: 5-[4'-[[2-Butyl-4-chloro-5-[ (triphenylmethoxy) methyl]-1H-imidazol-1-yl]methyl][1, 1'-biphenyl]-2-yl]-. Grades: Highly Purified. CAS No. 1006062-28-7. Pack Sizes: 2.5mg. US Biological Life Sciences.
An impurity found in Losartan tablets. Group: Biochemicals. Alternative Names: 2-Butyl-1-[[2'-[1-[[2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)trityl[1,1'-biphenyl]-4-yl]methyl]-1H-imidazol-5-yl]methyl]-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-4-chloro-1H-imidazole-5-methanol. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Losatuxizumab (ABT-806) is an anti- EGFR monoclonal antibody. Losatuxizumab binds to EGFR with EC 50 s of 0.96 nM for EGFR wild-type, 0.09 nM for EGFR C271A,C283A , 0.12 nM for EGFRvIII, 0.66 nM for EGFR1-501. Losatuxizumab can be used for research of EGFR-expressing cancers [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ABT-806. CAS No. 1801544-27-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99715.
Losigamone
Losigamone (AO-33) is an orally active antiepileptic compound. Losigamone blocks sodium channel. Losigamone stimulates the neuronal chloride channel and enhance chloride influx. Losigamone potentiates GABA-mediated responses and reduces epileptiform activity induced by chloride channel antagonists. Losigamone can be used for epilepsy research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AO-33; (±)-Losigamone; LSG. CAS No. 112856-44-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-106822.
Losmapimod
Losmapimod (GSK-AHAB) is a selective, potent, and orally active p38 MAPK inhibitor with pK i s of 8.1 and 7.6 for p38α and p38β, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK-AHAB; GW856553X; SB856553. CAS No. 585543-15-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10402.
Losmapimod
Losmapimod is a promising new agent against cardiovascular diseases. This drug works by inhibiting p38 MAP kinases, which play an important role in the development of atherosclerosis and heart failure caused by ischemic conditions. Losmapimod did not cause an improvement in exercise tolerance or lung function, despite being well-tolerated in this COPD population. The p38 MAPK inhibitor losmapimod (GW856553) attenuates the pro-inflammatory response in humans by reducing PIC production. Synonyms: Losmapimod; GW856553; GW-856553; GW 856553 GSK-AHAB; GW856553X; 6-[5-(cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl]-N-(2,2-dimethylpropyl)pyridine-3-carboxamide. Grades: 98%. CAS No. 585543-15-3. Molecular formula: C22H26FN3O2. Mole weight: 383.467.
Losmapimod
Losmapimod / GW856553 / GW856553X is a drug developed by GlaxoSmithKline which acts as a selective inhibitor of the enzyme family known as p38 mitogen-activated protein kinases (orally active p38 MAPK inhibitor with pKis of 8.1 and 7.6 for p38α and p38β, p38 respectively). Losmapimod is being studied for cardiovascular disease. Losmapimod is also being studied for a potential treatment for patients with COVID-19. Group: Fluorinated apis. Alternative Names: GW856553X. CAS No. 585543-15-3. Molecular formula: C22H26FN3O2. Mole weight: 383.46. Appearance: White to off-white solid powder. Purity: >98%. IUPACName: 6-[5-(cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl]-N-(2,2-dimethylpropyl)pyridine-3-carboxamide. Catalog: OFC585543153.
Losoxantrone
Losoxantrone is a DNA intercalator that was developed with the potential to replace anthracyclines. Losoxantrone is also a bioreductive drugs. In phase II trials, losoxantrone demonstrated a partial biochemical response rate of 25%, response in measurable disease sites in 22%, and improvement in clinical symptoms in one-third of patients. Uses: Antineoplastic agents. Synonyms: Biantrazole; CI-941; CI 941; CI941; DuP-941;DuP 941; DuP941; 7-Hydroxy-2-[2- (2-hydroxyethylamino) ethyl]-5-[2- (2-hydroxyethylamino) ethylamino]anthra[1, 9-cd]pyrazol-6 (2H) -one. CAS No. 88303-60-0. Molecular formula: C22H27N5O4. Mole weight: 425.49.
Lotaustralin
Lotaustralin is a cyanogenic glucoside isolated from Manihot esculenta [1]. Uses: Scientific research. Group: Natural products. CAS No. 1973415-50-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N5079.
Lotaustralin
Lotaustralin, a naturally occurring compound discovered across diverse plant species, manifests noteworthy anti-inflammatory and analgesic attributes through its adept regulation of pivotal biochemical pathways. Extensive investigations have illuminated Lotaustralin's therapeutic potential in combatting an array of ailments, encompassing cancer and neurodegenerative disorders. Synonyms: 2-(b-D-Glucopyranosyloxy)-2-methylbutyronitrile. CAS No. 534-67-8. Molecular formula: C11H19NO6. Mole weight: 261.27.
Lotaustralin (Mixture of Diastereomers)
A bioactive constituent of Chinese natural medicines. Synonyms: 2-(β-D-Glucopyranosyloxy)-2-methylbutyronitrile; 2-(β-D-Glucopyranosyloxy)-2-methyl-butanenitrile. Molecular formula: C11H19NO6. Mole weight: 261.27.
Lotaustralin Tetraacetate
Lotaustralin Tetraacetate is an intermediate in the synthesis of (R)-Lotaustralin, which is a bioactive constituent of Chinese natural medicines. Synonyms: Lotaustralin Tetraacetate (Ester). CAS No. 27749-93-5. Molecular formula: C19H27NO10. Mole weight: 429.42.
25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C24H31ClO7. CAS No. 82034-46-6. Prepack ID 28320367-25mg. Molecular Weight 466.95. See USA prepack pricing.
Loteprednol Etabonate
Loteprednol etabonate is an anti-inflammatory corticosteroid used in ophthalmology. Synonyms: ONO-2235; ONO2235; ONO2235; Loteprednol Etabonate; Lotemax; Alrex; HGP-1; Loterox; Locort. Grades: >98%. CAS No. 82034-46-6. Molecular formula: C24H31ClO7. Mole weight: 466.95.
Loteprednol Etabonate
Loteprednol etabonate (LE) is an orally active "soft" steroid belonging to a unique class of glucocorticoids. Loteprednol etabonate (LE) exhibits anti-inflammatory activity and has been used in optometry and ophthalmology [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 82034-46-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17358.
An ophthalmic corticosteroid. Used as an anti-inflammatory. Group: Biochemicals. Alternative Names: CDDD-5604, HGP-1, P-5604, Alrex, Lotemax. Grades: Highly Purified. CAS No. 82034-46-6. Pack Sizes: 10mg, 50mg, 100mg, 250mg. US Biological Life Sciences.
Worldwide
Loteprednol Etabonate-d3
Labeled Loteprednol Etabonate, an ophthalmic corticosteroid. Used as an anti-inflammatory. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.