American Chemical Suppliers

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Product
Low Viscosity Alcohol Soluble Polyamide Resin ALFA06 This resin product is soluble in isopropyl alcohol alone. Uses: It is suitable for aniline printing inks (flexographic ink). Group: Alcohol soluble polyamide resins. Alfa Chemistry Materials 3
Low Viscosity Alcohol Soluble Polyamide Resin ALFA07 This resin product is soluble in isopropyl alcohol alone. Uses: It is suitable for aniline printing inks (flexographic ink). Group: Alcohol soluble polyamide resins. Alfa Chemistry Materials 3
Low Viscosity Alcohol Soluble Polyamide Resin ALFA08 This resin product is soluble in isopropyl alcohol alone. Uses: It is suitable for aniline printing inks (flexographic ink). Group: Alcohol soluble polyamide resins. Alfa Chemistry Materials 3
Low volatile steam coal (S) certified Reference Material. Group: Certified reference materials (crms). Alfa Chemistry Analytical Products
Loxapine Loxapine is a typical antipsychotic medication, used primarily in the treatment of schizophrenia. Uses: Loxapine is a d2/d4 dopamine receptor and 5-ht2a/2b, 5-h7 serotonin receptor antagonist and often be used in the primary treatment of schizophrenia. Synonyms: 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b, f][1, 4]oxazepine; C07104. Grades: > 95%. CAS No. 1977-10-2. Molecular formula: C18H18ClN3O. Mole weight: 327.81. BOC Sciences 6
Loxapine Loxapine is an orally active dopamine inhibitor, 5-HT receptor antagonist and also a dibenzoxazepine anti-psychotic agent [1] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1977-10-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-17390. MedChemExpress MCE
Loxapine-d8 Hydrochloride A D2/D4-Dopamine receptor antagonist. A serotonergic receptor antagonist. A dibenzoxazepine antipsychotic agent. Group: Biochemicals. Alternative Names: 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b, f][1, 4]oxazepine-d8 Hydrochloride; Oxilapine-d8 Hydrochloride; CL-62362-d8 Hydrochloride; S-805-d8 Hydrochloride; SUM-3170-d8 Hydrochloride. Grades: Highly Purified. CAS No. 1246820-19-8. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
Worldwide
Loxapine N-Glucuronide Chloride Loxapine N-Glucuronide Chloride is a metabolite of Loxapine, a dibenzoxazepine antipsychotic agent. Synonyms: 4-(2-Chlorodibenz[b,f][1,4]oxazepin-11-yl)-1-β-D-glucopyranuronosyl-1-methyl-piperazinium Chloride. Grades: > 95%. CAS No. 145823-23-0. Molecular formula: C24H27Cl2N3O7. Mole weight: 540.39. BOC Sciences 6
Loxapine N-Oxide Loxapine N-Oxide. Group: Biochemicals. Alternative Names: 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b, f][1, 4]oxazepine, Succinate; Oxilapine; CL-62362; S-805; SUM-3170. Grades: Highly Purified. CAS No. 25967-34-4. Pack Sizes: 10mg. Molecular Formula: C18H18ClN3O2, Molecular Weight: 343.81. US Biological Life Sciences. USBiological 3
Worldwide
Loxapine N-Oxide Loxapine N-Oxide is a metabolite of Loxapine, a D2/D4-Dopamine receptor antagonist. It is a serotonergic receptor antagonist that acts as a dibenzoxazepine antipsychotic agent. Synonyms: 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b, f][1, 4]oxazepine, Succinate; Oxilapine; CL-62362; S-805; SUM-3170. Grades: > 95%. CAS No. 25967-34-4. Molecular formula: C18H18ClN3O2. Mole weight: 343.81. BOC Sciences 6
Loxapine Related Compound A United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products 2
Loxapine succinate Loxapine succinate is an orally active dopamine inhibitor, 5-HT receptor antagonist and also a dibenzoxazepine anti-psychotic agent. Loxapine can also suppresses bacterial efflux pump activity and inhibit intracellular multiple-antibiotic-resistant Salmonella enterica serovar Typhimurium in macrophages [1] [4] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 27833-64-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-17390A. MedChemExpress MCE
Loxapine Succinate United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardsapi standardspharmaceutical toxicology. Alternative Names: Dibenz[b,f][1,4]oxazepine, 2-chloro-11-(4-methyl-1-piperazinyl)-, butanedioate, 2-Chloro-11-(4-methyl-1-piperazinyl)-dibenz[b,f][1,4]oxazepine succinate, Loxapac, 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine butanedioate, Loxitane Capsules,Loxapine Succinate, Succinic acid, compd. with 2-chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine, Loxitane, CL 71563, Daxolin. Alfa Chemistry Analytical Products
Loxapine Succinate Loxapine Succinate is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent.oxapine is a typical antipsychotic medication, used primarily in the treatment of schizophrenia. Trade names for loxapine taken by mouth include Loxapac and Loxitane; the inhalable form is approved as Adasuve. Synonyms: Loxapine Succinate. Grades: >98%. CAS No. 27833-64-3. Molecular formula: C18H18ClN3O.C4H6O4. Mole weight: 445.9. BOC Sciences 10
Loxapine, Succinate (2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b, f][1, 4]oxazepine, Succinate) A D2/D4-Dopamine receptor antagonist. A serotonergic receptor antagonist. A dibenzoxazepine antipsychotic agent. Group: Biochemicals. Alternative Names: 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b, f][1, 4]oxazepine, Succinate. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences. USBiological 1
Worldwide
Loxapine succinate salt solid. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
Loxapine succinate salt Loxapine succinate salt. Group: Biochemicals. Grades: Highly Purified. CAS No. 27833-64-3. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C18H18ClN3O·C4H6O4. US Biological Life Sciences. USBiological 7
Worldwide
Loxiglumide Loxiglumide is a cholecystokinin ( CCK-1 ) receptor antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CR-1505. CAS No. 107097-80-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B2154. MedChemExpress MCE
Loxiglumide Loxiglumide is an orally active, potent and selective small-molecule antagonist of the cholecystokinin receptor CCKA. It stimulates calorie intake and hunger feelings in humans. It could antagonize the CCK-induced reduction of gastric emptying in rats, accelerate the intestinal transport and accelerate the gallbladder emptying in mice. It inhibits pancreatic secretion of digestive enzymes, and also blocks CCK-induced gastric secretions and emptying. Uses: Loxiglumide stimulates calorie intake and hunger feelings in humans. it inhibits pancreatic secretion of digestive enzymes. Synonyms: CR-1505; CR 1505; CR1505; D,L-4-(3,4-dichlorobenzoylamino)-5-(n-3-methoxypropylpentylamino)-5-oxo-pentanoicacid;Pentanoicacid,4-((3,4-dichlorobenzoyl)amino)-5-((3-methoxypropyl)pentylamino);CR-1505;CR1505;4-(3,4-Dichlorobenzamido)-5-((3-methoxypropyl)(pentyl)amino)-5-oxopentanoic acid. Grades: 95%. CAS No. 107097-80-3. Molecular formula: C21H30Cl2N2O5. Mole weight: 461.38. BOC Sciences 9
Loxiglumide ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
LOXIOL® 895 Ethylene glycol distearate. Uses: Well-balanced, internal lubricant for production of many PVC articles. Group: Polymer Additives. Alternative Name: EGDS. Grade: 1. Pack Sizes: Bags/Super sacks. Improves the flow of the polymer melt in complex articles.. Emery Oleochemicals
LOXIOL® G 32 Fatty acid ester. Uses: Internal /external lubricant in PVC/Release agent for PC, PP, PA and SB resins. Group: Polymer Additives. Alternative Name: Stearyl stearate. Grade: 1. CAS Number: Proprietary. Pack Sizes: Bags/Super sacks. Greater processing window when used in combination with calcium stearate than standard Paraffin/ca.stearate /Ox.PE formulations.. Emery Oleochemicals
LOXIOL® G 60 C16/18 phthalate. Uses: Internal lubricant for PVC compounds. Group: Polymer Additives. Alternative Name: Fatty acid ester . Grade: 1. CAS Number: Proprietary. Pack Sizes: Bags/Super sacks. Typical non-FDA uses include: extrusion of window and technical profiles.. Emery Oleochemicals
LOXIOL® P 1141 Fatty acid ester compound. Uses: Internal liquid glycerin ester lubricant for PVC. Group: Polymer Additives. Alternative Name: Fatty acid ester. Grade: 1. CAS Number: Proprietary. Pack Sizes: Drums/totes/bulk. Use in rigid PVC application that requires high transparency.. Emery Oleochemicals
LOXIOL® P 861/3.5 Pentaerythiol tetra stearate. Uses: Universal release agent for polar polymers mainly for PC and ABS resins. Group: Polymer Additives. Alternative Name: PETS. Grade: 1. CAS Number: Proprietary. Pack Sizes: Bags/Super sacks. Prevents the polymer melt from sticking to the hot machine parts and facilitates mold release at higher temperatures.. Emery Oleochemicals
Loxistatin Acid Cas No. 76684-89-4. BOC Sciences 11
LOXL2 human recombinant, ?86% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
LOXO-101 (ARRY-470) LOXO-101, also known as ARRY-470, is an orally bioavailable, potent, ATP-competitive inhibitor of TRKA, TRKB, and TRKC. LOXO-101 has IC50 values in the low nanomolar range for inhibition of all three TRK family members in binding and cellular assays, with 100x selectivity over other kinases, and has shown acceptable pharmaceutical properties and safety in nonclinical models. Synonyms: Larotrectinib; ARRY 470; LOXO 101; (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide. Grades: 98%. CAS No. 1223403-58-4. Molecular formula: C21H22F2N6O2. Mole weight: 428.44. BOC Sciences 11
LOXO-101 sulfate The sulfate salt form of LOXO-101, also called Larotrectinib, which is an ATP-competitive inhibitor of tropomyosin receptor kinases. It was approved by FDA for the treatment of metastatic solid tumors. Synonyms: LOXO-101 sulfate; LOXO 101 sulfate; LOXO101 sulfate; Larotrectinib sulfate; (3S)-N-[5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxypyrrolidine-1-carboxamide sulfate. Grades: >95%. CAS No. 1223405-08-0. Molecular formula: C21H24F2N6O6S. Mole weight: 526.51. BOC Sciences 9
LOXO-195 LOXO-195 is an orally available inhibitor of the tyrosine receptor kinases (TRK). It binds to TRK including the fusion proteins containing sequences from neurotrophic tyrosine receptor kinase (NTRK) types 1 (NTRK1), 2 (NTRK2), and 3 (NTRK3), which inhibits the interaction of neurotrophin and TRK, inducing cell apoptosis in tumors overexpressing TRK and NTRK. Uses: Enzyme inhibitors. Synonyms: Selitrectinib. Grades: ≥98%. CAS No. 2097002-61-2. Molecular formula: C20H21FN6O. Mole weight: 380.42. BOC Sciences 10
Loxodellic acid Loxodellic acid, as the principal constant constituent, is a lower homologue of glomelliferic acid from the new species Parmelia loxodella Essl. from Australia (including Tasmania) and New Zealand. Synonyms: Benzoic acid, 2-hydroxy-4-[[2-hydroxy-4-methoxy-6-(2-oxopentyl)benzoyl]oxy]-6-propyl-. CAS No. 67121-37-3. Molecular formula: C23H26O8. Mole weight: 430.45. BOC Sciences 6
Loxodellonic acid Loxodellonic acid is a depside from the Lichen Neofuscelia subincerta. Synonyms: ACMC-20mit2; 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylicacid, 8-hydroxy-3-methoxy-11-oxo-1-(2-oxopentyl)-6-propyl-. CAS No. 113689-49-9. Molecular formula: C23H24O8. Mole weight: 428.43. BOC Sciences 6
Loxodin Loxodin is a depsidone isolated from Parmelia flavescentireagens Gyel. Synonyms: Neoloxodic acid; 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 3,8-dihydroxy-11-oxo-6-pentyl-1-valeryl-, methyl ester (8CI). CAS No. 29813-50-1. Molecular formula: C25H28O8. Mole weight: 456.48. BOC Sciences 6
Loxoprofen Loxoprofen. Group: Biochemicals. Alternative Names: α -Methyl-4-[ (2-oxocyclopentyl) methyl]benzeneacetic Acid; 2- [4- [ (2-Oxocyclopentan-1-yl) methyl] phenyl] propionic Acid; 2- [4- [ (2-Oxocyclopentyl) methyl] phenyl] propionic Acid. Grades: Highly Purified. CAS No. 68767-14-6. Pack Sizes: 10mg. Molecular Formula: C15H18O3, Molecular Weight: 246.3. US Biological Life Sciences. USBiological 3
Worldwide
Loxoprofen Loxoprofen is a non-steroidal, orally active anti-inflammatory agent with analgesic and anti-pyretic properties. Loxoprofen is a nonselective COX inhibitor with IC 50 s of 6.5 and 13.5 μM for COX-1 and COX-2, respectively. Loxoprofen can reduce atherosclerosis and shows antitumor activity [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 68767-14-6. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-B0578. MedChemExpress MCE
Loxoprofen Loxoprofen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group, which also includes ibuprofen and naproxen among others. It is a non-selective cyclooxygenase inhibitor, and works by reducing the synthesis of prostaglandins from arachidonic acid. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: α-Methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic Acid; 2-[4-[(2-Oxocyclopentan-1-yl)methyl]phenyl]propionic Acid; 2-[4-[ (2-Oxocyclopentyl) methyl]phenyl]propionic Acid. Grades: >98%. CAS No. 68767-14-6. Molecular formula: C15H18O3. Mole weight: 246.3. BOC Sciences
Loxoprofen solid. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
Loxoprofen solid. Uses: For analytical and research use. Group: Fluorescence/luminescence spectroscopy. CAS No. 68767-14-6. Pack Sizes: 5MG. Mole weight: 246.30. Catalog: AP68767146. Alfa Chemistry Analytical Products 4
Loxoprofen Impurity 28 Loxoprofen Impurity 28. Uses: For analytical and research use. Group: Impurity standards. CAS No. 141-28-6. Molecular formula: C10H18O4. Mole weight: 202.25. Catalog: APB141286. Alfa Chemistry Analytical Products 4
Loxoprofen Impurity 35 Loxoprofen Impurity 35. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(4-((1-hydroxy-2-oxocyclopentyl)methyl)phenyl)propanoic acid. CAS No. 1091621-62-3. Molecular formula: C15H18O4. Mole weight: 262.3. Catalog: APB1091621623. Alfa Chemistry Analytical Products 4
Loxoprofen Impurity 35 Loxoprofen Impurity 35. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1072443-75-4. Molecular formula: C11H13BrO2. Mole weight: 257.13. Catalog: APB1072443754. Alfa Chemistry Analytical Products 4
Loxoprofen Impurity 58 Loxoprofen Impurity 58. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10472-24-9. Molecular formula: C7H10O3. Mole weight: 142.15. Catalog: APB10472249. Alfa Chemistry Analytical Products 4
Loxoprofen impurity 80 Loxoprofen impurity 80. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1027957-36-3. Molecular formula: C17H20O5. Mole weight: 304.34. Catalog: APB1027957363. Alfa Chemistry Analytical Products 4
Loxoprofen Impurity D Loxoprofen Impurity D. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-(4-(1-carboxyethyl)phenyl)-5-oxohexanoic acid. CAS No. 1091621-61-2. Molecular formula: C15H18O5. Mole weight: 278.3. Catalog: APB1091621612. Alfa Chemistry Analytical Products 4
Loxoprofen Related Compound 1 Loxoprofen Related Compound 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1091621-63-4. Molecular formula: C25H36O3. Mole weight: 384.56. Catalog: APB1091621634. Alfa Chemistry Analytical Products 4
Loxoprofen Related Compound 1 Grades: > 95%. Molecular formula: C25H36O3. Mole weight: 384.56. BOC Sciences 6
Loxoprofen Related Compound 2 (Mixture of Diastereomers) An impurity of Loxoprofen, a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. Synonyms: 2- (4- ( (1-hydroxy-2-oxocyclopentyl) methyl) phenyl) propanoic acid. Grades: > 95%. CAS No. 1091621-62-3. Molecular formula: C15H18O4. Mole weight: 262.31. BOC Sciences 8
Loxoprofen Ring-opening Impurity Loxoprofen Ring-opening Impurity is a degradation product of Loxoprofen, a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. Synonyms: 4-(1-Carboxyethyl)-δ-oxo-benzenehexanoic Acid; 2-[4-(2-Oxo-6-carboxy-pentyl)phenyl-propanoic Acid. Grades: > 95%. CAS No. 1091621-61-2. Molecular formula: C15H18O5. Mole weight: 278.3. BOC Sciences 8
Loxoprofen sodium Loxoprofen sodium is a non-steroidal, orally active anti-inflammatory agent with analgesic and anti-pyretic properties. Loxoprofen sodium is a nonselective COX inhibitor with IC 50 s of 6.5 and 13.5 μM for COX-1 and COX-2, respectively. Loxoprofen sodium can reduce atherosclerosis and shows antitumor activity [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 80382-23-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B0578A. MedChemExpress MCE
Loxoprofen Sodium The parent acid, loxoprofen, is a prodrug that is rapidly converted to its active trans-alcohol metabolite following oral administration. Synonyms: More Synonyms. Grades: >98%. CAS No. 80382-23-6. Molecular formula: C15H17NaO3. Mole weight: 268.28. BOC Sciences 10
Loxoprofen Sodium A non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. It becomes active after metabolism in the body and inhibits the activation of cyclooxygenase. Group: Biochemicals. Alternative Names: α -Methyl-4-[ (2-oxocyclopentyl) methyl]benzeneacetic Acid Sodium Salt; CS 600; Loxonin; Sodium 2- [4- [ (2-Oxocyclopentyl) methyl] phenyl] propionate; Sodium Loxoprofen. Grades: Highly Purified. CAS No. 80382-23-6. Pack Sizes: 25mg. US Biological Life Sciences. USBiological 2
Worldwide
Loxoprofen Sodium USP Sodium 2-[4-(2-Oxocyclopentyl-1-methyl)phenyl]propionate, α-Methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic acid sodium salt, Koloxo. anti-coagulant, Factor X inhibitor. Grades: USP. CAS No. 80382-23-6. Product ID: 8-04756. Molecular formula: C15H17NaO3. Mole weight: 268.29. CarboMer Inc
Loxoprofen USP α-Methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic acid, Koloxo. long-acting basal insulin analogue, helping control the blood sugar level of those with type 1 and type 2 diabetes mellitus. It is an analogue of human insulin made by replacing the asparagine residue at position A21 of the A-chain with glycine and adding two arginines to the C-terminus (positions B31 and 32) of the B-chain. Grades: USP. CAS No. 68767-14-6. Product ID: 8-04755. Molecular formula: C15H18O3. Mole weight: 246.3. CarboMer Inc
Loxoribine Guanosine analog derivatized at position N7 and C8. Very potent immunostimulatory compound that increases cytokine production. Antitumor and antiviral activity compound. Potent and selective synthetic ligand for Toll-like receptor 7 (TLR7). Co-incubation with thymidine homopolymer oligodeoxynucleotides (ODN) redirected the stimulatory effect of loxoribine away from TLR7 toward TLR8. Induces autophagy and autophagy-induced cell death in Caco-2 cells. Shows adjuvant activity to increase the effectiveness of vaccines. Group: Biochemicals. Alternative Names: 7-Allyl-8-oxoguanosine; RWJ 21757, 7-Allyl-2-amino-9-(3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-7,9-dihydro-1H-purine-6,8-dione. Grades: Highly Purified. CAS No. 121288-39-9. Pack Sizes: 5mg, 25mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. USBiological 4
Worldwide
Loxoribine It is a small-molecule immunostimulant, toll-like receptor 7 (TLR7) agonist, TLR7 ligand and antitumor agent. Synonyms: 7,8-Dihydro-8-oxo-7-allyl-guanosine; RWJ-21757; RWJ 21757; RWJ21757; 7-Allyl-8-oxoguanosine; Loxoribina; 7-Allyl-7,8-dihydro-8-oxoguanosine; 7-Allyl-2-amino-9-beta-D-ribofuranosylpurine-6,8(1H,9H)-dione. Grades: ≥95%. CAS No. 121288-39-9. Molecular formula: C13H17N5O6. Mole weight: 339.30. BOC Sciences 3
LP117 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
LP 12 hydrochloride LP 12 hydrochloride is a 5-HT7 receptor agonist. It can induce relaxation of substance P-induced contractions in guinea pig ileum with EC50 value of 1.77 μM. Synonyms: LP 12 hydrochloride; LP12 hydrochloride; LP-12 hydrochloride; 4-(2-Diphenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 1185136-22-4. Molecular formula: C32H39N3O.HCl. Mole weight: 518.13. BOC Sciences 10
LP 12 hydrochloride hydrate ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
LP17 LP17 (LQVTDSGLYRCVIYHPP) is a BBB-penetrable triggering receptor expressed on myeloid cells (TREM-1) inhibitory peptide. LP17 substantially alleviates ischemia-induced infarction and neuronal injury. LP17 can get access into brain and block TREM-1[1]. Uses: Scientific research. Group: Peptides. Alternative Names: LQVTDSGLYRCVIYHPP. CAS No. 887255-16-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3400. MedChemExpress MCE
LP-184 LP-184 (compound 6), an acylfulvene analog, inhibits tumor growth. LP-184 has potent anti-cancer activity in the ovarian, colon, prostate and pancreatic cell lines. (patent WO2007019308A2). Uses: Scientific research. Group: Signaling pathways. CAS No. 924835-67-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-139453. MedChemExpress MCE
LP1A LP1A is an antibacterial peptide isolated from Manduca sexta. Synonyms: Gln-Arg-Phe-Ser-Gln-Pro-Thr-Phe-Lys-Leu-Pro-Gln-Gly-Arg-Leu-Thr-Leu-Ser-Arg-Lys-Phe. Grades: 95.8%. Molecular formula: C116H187N35O29. Mole weight: 2535.98. BOC Sciences 4
LP 20 hydrochloride LP 20 hydrochloride is a ligand of the 5-HT7 receptor. It shows agonist and antagonist activity. Synonyms: LP 20 hydrochloride; LP20 hydrochloride; LP-20 hydrochloride; 1-(4'-Methoxy[1,1-biphenyl]-2-yl)piperazine hydrochloride. Grades: ≥98% by HPLC. CAS No. 1386928-34-2. Molecular formula: C17H20N2O.HCl. Mole weight: 304.81. BOC Sciences 10
LP-211 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
LP-261 LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest. Screening in the NCI60 cancer cell lines resulted in a mean GI50 of approximately 100 nM. LP-261 is a very potent inhibitor of angiogenesis, preventing microvessel outgrowth in the rat aortic ring assay and HUVEC cell proliferation at nanomolar concentrations. Complete inhibition of tumor growth was achieved in the PC3 xenograft model and shown to be schedule dependent. Excellent inhibition of tumor growth in the SW620 model was observed, comparable with paclitaxel. Combining oral, low dose LP-261 with bevacizumab led to significantly improved tumor inhibition. Oral LP-261 is very effective at inhibiting tumor growth in multiple mouse xenograft models and is well tolerated. Synonyms: LP261; LP 261. Grades: 99%. CAS No. 915412-67-8. Molecular formula: C22H19N3O4S. Mole weight: 421.47. BOC Sciences 11
LP44 ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
LP 44 LP 44 is a 5-HT7 receptor agonist with Ki value of 0.22 nM that displays selectivity over 5-HT1A and 5-HT2A receptors (200- and > 1000-fold respectively). It induces relaxation of substance P-induced guinea pig ileum contraction with an EC50 value of 2.56 μM. Synonyms: LP-44; LP 44; LP44; 4-[2-(Methylthio)phenyl]-N-(1,2,3,4-tetrahydro-1-naphthalenyl)-1-piperazinehexanamide hydrochloride. Grades: ≥98% by HPLC. CAS No. 824958-12-5. Molecular formula: C27H37N3OS.HCl. Mole weight: 488.13. BOC Sciences 10
LP-44 Hydrochloride A potent agonist of the 5-HT7 serotonin receptor (Ki= 0.22nM) with good selectivity against other 5-HT receptors (5-HT1A Ki = 52.7nM, 5-HT1B Ki = 60nM). Often used in conjuction with the selective 5-HT7 receptor antagonist, SB-269970. Group: Biochemicals. Grades: Highly Purified. CAS No. 824958-12-5. Pack Sizes: 10mg. Molecular Formula: C??H??ClN?OS. US Biological Life Sciences. USBiological 4
Worldwide
LP-533401 LP-533401 is an inhibitor of tryptophan 5-hydroxylase 1 (Tph1) that suppresses serotonin production in the gut. It prevents the development of osteoporosis in ovariectomized and aged mice. Synonyms: (2S)-2-Amino-3-[4-[2-amino-6-[2,2,2-trifluoro-1-[4-(3-fluorophenyl)phenyl]ethoxy]pyrimidin-4-yl]phenyl]propanoic acid. Grades: ≥98%. CAS No. 945976-43-2. Molecular formula: C27H22F4N4O3. Mole weight: 526.5. BOC Sciences 10
LP-922056 LP-922056 is an orally active, highly potent Notum Pectinacetylesterase inhibitor with EC50s of 21 nM, 55 nM in human and mouse cellular assay, respectively. LP-922056 significantly increases midshaft femur cortical bone thickness in mice and rats[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1365060-22-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131034. MedChemExpress MCE
LP-922761 LP-922761 is a potent AAK1 inhibitor (IC50 values are 4.8 and 7.6 nM in enzyme and cell assays, respectively). Synonyms: tert-Butyl (2-((3-(4-carbamoylphenyl)imidazo[1,2-b]pyridazin-6-yl)amino)ethyl)(methyl)carbamate. Grades: ≥98% by HPLC. CAS No. 1454808-95-7. Molecular formula: C21H26N6O3. Mole weight: 410.47. BOC Sciences 9

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