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Loxoprofen Impurity 48. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(1-methoxy-1-oxopropan-2-yl)benzyl 2-oxocyclopentanecarboxylate. Molecular Formula: C17H20O5. Mole Weight: 304.34. Catalog: APB02060.
Loxoprofen Impurity 49
Loxoprofen Impurity 49. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2- (4- ( ( (2-oxocyclopentanecarbonyl) oxy) methyl) phenyl) propanoic acid. Molecular Formula: C16H18O5. Mole Weight: 290.31. Catalog: APB02059.
Loxoprofen Impurity 50
Loxoprofen Impurity 50. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-methoxy-5-(4-(1-methoxy-1-oxopropan-2-yl)benzyl)-6-oxohexanoic acid. Molecular Formula: C18H24O6. Mole Weight: 336.38. Catalog: APB01608.
Loxoprofen Impurity 50
Loxoprofen Impurity 50. Uses: For analytical and research use. Group: Impurity standards. CAS No. 145679-19-2. Molecular Formula: C10H10O4. Mole Weight: 194.19. Catalog: APB145679192.
Loxoprofen Impurity 51
Loxoprofen Impurity 51. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl 2-((4-(1-methoxy-1-oxopropan-2-yl)benzyl)oxy)cyclopent-1-enecarboxylate. Molecular Formula: C18H22O5. Mole Weight: 318.36. Catalog: APB02056.
Loxoprofen Impurity 52
Loxoprofen Impurity 52. Uses: For analytical and research use. Group: Impurity standards. CAS No. 69956-76-9. Molecular Formula: C15H16O3. Mole Weight: 244.29. Catalog: APB69956769.
Loxoprofen Impurity 53
Loxoprofen Impurity 53. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H24O5. Mole Weight: 320.39. Catalog: APB08480.
Loxoprofen Impurity 54
Loxoprofen Impurity 54. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl 2-(4-(4-methylbenzyl)phenyl)propanoate. Molecular Formula: C18H20O2. Mole Weight: 268.35. Catalog: APB02058.
Loxoprofen Impurity 56
Loxoprofen Impurity 56. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(4-(4-methylbenzyl)phenyl)propanoic acid. Molecular Formula: C17H18O2. Mole Weight: 254.32. Catalog: APB02057.
Loxoprofen Impurity 57
Loxoprofen Impurity 57. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(4-(2-methylbenzyl)phenyl)propanoic acid. Molecular Formula: C17H18O2. Mole Weight: 254.32. Catalog: APB02054.
Loxoprofen Impurity 58
Loxoprofen Impurity 58. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10472-24-9. Molecular Formula: C7H10O3. Mole Weight: 142.15. Catalog: APB10472249.
Loxoprofen Impurity 59
Loxoprofen Impurity 59. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-(4-(1-ethoxy-1-oxopropan-2-yl)phenyl)-5-oxohexanoic acid. Molecular Formula: C17H22O5. Mole Weight: 306.35. Catalog: APB01607.
Loxoprofen Impurity 60
Loxoprofen Impurity 60. Uses: For analytical and research use. Group: Impurity standards. CAS No. 334948-52-6. Molecular Formula: C13H18O8. Mole Weight: 302.28. Catalog: APB334948526.
Loxoprofen Impurity 61
Loxoprofen Impurity 61. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H22O5. Mole Weight: 318.37. Catalog: APB08481.
Loxoprofen Impurity 62
Loxoprofen Impurity 62. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C19H22O7. Mole Weight: 362.38. Catalog: APB08483.
Loxoprofen Impurity 63
Loxoprofen Impurity 63. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C15H17NaO4. Mole Weight: 284.29. Catalog: APB08482.
Loxoprofen Impurity 64
Loxoprofen Impurity 64. Uses: For analytical and research use. Group: Impurity standards. CAS No. 639857-67-3. Molecular Formula: C14H18O. Mole Weight: 202.3. Catalog: APB639857673.
Loxoprofen Impurity 66
Loxoprofen Impurity 66. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C15H20O5. Mole Weight: 280.32. Catalog: APB08485.
Loxoprofen Impurity 67
Loxoprofen Impurity 67. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C16H20O3. Mole Weight: 260.33. Catalog: APB08484.
Loxoprofen Impurity 68
Loxoprofen Impurity 68. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C15H20O3. Mole Weight: 248.32. Catalog: APB08487.
Loxoprofen Impurity 69
Loxoprofen Impurity 69. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H24O5. Mole Weight: 320.39. Catalog: APB08486.
Loxoprofen Impurity 70
Loxoprofen Impurity 70. Uses: For analytical and research use. Group: Impurity standards. CAS No. 825-25-2. Molecular Formula: C10H14O. Mole Weight: 150.22. Catalog: APB825252.
Loxoprofen Impurity 71
Loxoprofen Impurity 71. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C15H20O5. Mole Weight: 208.32. Catalog: APB08490.
Loxoprofen Impurity 72
Loxoprofen Impurity 72. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C17H22O5. Mole Weight: 306.36. Catalog: APB08489.
Loxoprofen Impurity 73
Loxoprofen Impurity 73. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C17H22O5. Mole Weight: 306.36. Catalog: APB08488.
Loxoprofen Impurity 74
Loxoprofen Impurity 74. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H24O6. Mole Weight: 336.38. Catalog: APB08491.
Loxoprofen Impurity 75
Loxoprofen Impurity 75. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H24O6. Mole Weight: 336.38. Catalog: APB08492.
Loxoprofen Impurity 76
Loxoprofen Impurity 76. Uses: For analytical and research use. Group: Impurity standards. CAS No. 77846-90-3. Molecular Formula: C10H12O4. Mole Weight: 196.2. Catalog: APB77846903.
Loxoprofen Impurity 77
Loxoprofen Impurity 77. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C15H21NaO5. Mole Weight: 304.32. Catalog: APB08495.
Loxoprofen Impurity 78
Loxoprofen Impurity 78. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H22O5. Mole Weight: 318.37. Catalog: APB08493.
Loxoprofen Impurity 79
Loxoprofen Impurity 79. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C15H18O4. Mole Weight: 262.31. Catalog: APB08494.
Loxoprofen Impurity 79
Loxoprofen Impurity 79. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2274853-20-0. Molecular Formula: C18H22O5. Mole Weight: 318.37. Catalog: APB2274853200.
Loxoprofen impurity 80
Loxoprofen impurity 80. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1027957-36-3. Molecular Formula: C17H20O5. Mole Weight: 304.34. Catalog: APB1027957363.
Loxoprofen Impurity 80
Loxoprofen Impurity 80. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H24O5. Mole Weight: 320.39. Catalog: APB08496.
Loxoprofen impurity 81
Loxoprofen impurity 81. Uses: For analytical and research use. Group: Impurity standards. CAS No. 83648-77-5. Molecular Formula: C15H20O3. Mole Weight: 248.32. Catalog: APB83648775.
Loxoprofen Impurity 81
Loxoprofen Impurity 81. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H24O5. Mole Weight: 320.39. Catalog: APB08497.
Loxoprofen Impurity 82
Loxoprofen Impurity 82. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H24O5. Mole Weight: 320.39. Catalog: APB08498.
Loxoprofen Impurity 83
Loxoprofen Impurity 83. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H24O5. Mole Weight: 320.39. Catalog: APB08499.
Loxoprofen Impurity 84
Loxoprofen Impurity 84. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H24O5. Mole Weight: 320.39. Catalog: APB08500.
Loxoprofen Impurity 85
Loxoprofen Impurity 85. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H24O5. Mole Weight: 320.39. Catalog: APB08501.
Loxoprofen Impurity 86
Loxoprofen Impurity 86. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H24O5. Mole Weight: 320.39. Catalog: APB08502.
Loxoprofen Impurity 87
Loxoprofen Impurity 87. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H24O5. Mole Weight: 320.39. Catalog: APB08503.
Loxoprofen Impurity 9
Loxoprofen Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 79443-97-3. Molecular Formula: C11H14O2. Mole Weight: 178.23. Catalog: APB79443973.
Loxoprofen Impurity C
Loxoprofen Impurity C. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl 2- (4- ( (2-oxocyclopentyl) methyl) phenyl) propanoate. CAS No. 81762-92-7. Molecular Formula: C16H20O3. Mole Weight: 260.33. Catalog: APB81762927.
Loxoprofen Impurity D
Loxoprofen Impurity D. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-(4-(1-carboxyethyl)phenyl)-5-oxohexanoic acid. CAS No. 1091621-61-2. Molecular Formula: C15H18O5. Mole Weight: 278.3. Catalog: APB1091621612.
Loxoprofen Impurity N
Loxoprofen Impurity N. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(4-formylphenyl)propanoic acid. CAS No. 43153-07-7. Molecular Formula: C10H10O3. Mole Weight: 178.18. Catalog: APB43153077.
Loxoprofen Related Compound 1
Loxoprofen Related Compound 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1091621-63-4. Molecular Formula: C25H36O3. Mole Weight: 384.56. Catalog: APB1091621634.
Loxoprofen Related Compound 2 (Mixture of Diastereomers)
An impurity of Loxoprofen, a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. Synonyms: 2- (4- ( (1-hydroxy-2-oxocyclopentyl) methyl) phenyl) propanoic acid. Grades: > 95%. CAS No. 1091621-62-3. Molecular formula: C15H18O4. Mole weight: 262.31.
Loxoprofen Related Compound 6
Loxoprofen Related Compound 6. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C21H31NO5. Mole Weight: 377.48. Catalog: APB10771.
Loxoprofen Ring-opening Impurity
Loxoprofen Ring-opening Impurity is a degradation product of Loxoprofen, a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. Synonyms: 4-(1-Carboxyethyl)-δ-oxo-benzenehexanoic Acid; 2-[4-(2-Oxo-6-carboxy-pentyl)phenyl-propanoic Acid. Grades: > 95%. CAS No. 1091621-61-2. Molecular formula: C15H18O5. Mole weight: 278.3.
Loxoprofen sodium
Loxoprofen sodium is a non-steroidal, orally active anti-inflammatory agent with analgesic and anti-pyretic properties. Loxoprofen sodium is a nonselective COX inhibitor with IC 50 s of 6.5 and 13.5 μM for COX-1 and COX-2, respectively. Loxoprofen sodium can reduce atherosclerosis and shows antitumor activity [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 80382-23-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B0578A.
Loxoprofen Sodium
Loxoprofen Sodium. Uses: For analytical and research use. Group: Impurity standards. CAS No. 80382-23-6. Molecular Formula: C15H17NaO3. Mole Weight: 268.29. Catalog: APB80382236.
Loxoprofen Sodium
The parent acid, loxoprofen, is a prodrug that is rapidly converted to its active trans-alcohol metabolite following oral administration. Synonyms: More Synonyms. Grades: >98%. CAS No. 80382-23-6. Molecular formula: C15H17NaO3. Mole weight: 268.28.
Loxoprofen Sodium
A non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. It becomes active after metabolism in the body and inhibits the activation of cyclooxygenase. Group: Biochemicals. Alternative Names: α -Methyl-4-[ (2-oxocyclopentyl) methyl]benzeneacetic Acid Sodium Salt; CS 600; Loxonin; Sodium 2- [4- [ (2-Oxocyclopentyl) methyl] phenyl] propionate; Sodium Loxoprofen. Grades: Highly Purified. CAS No. 80382-23-6. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Loxoprofen-trans-Hydroxy Impurity
Loxoprofen-trans-Hydroxy Impurity. Uses: For analytical and research use. Group: Impurity standards. CAS No. 88378-21-6. Molecular Formula: C15H20O3. Mole Weight: 248.32. Catalog: APB88378216.
Loxoribine
Guanosine analog derivatized at position N7 and C8. Very potent immunostimulatory compound that increases cytokine production. Antitumor and antiviral activity compound. Potent and selective synthetic ligand for Toll-like receptor 7 (TLR7). Co-incubation with thymidine homopolymer oligodeoxynucleotides (ODN) redirected the stimulatory effect of loxoribine away from TLR7 toward TLR8. Induces autophagy and autophagy-induced cell death in Caco-2 cells. Shows adjuvant activity to increase the effectiveness of vaccines. Group: Biochemicals. Alternative Names: 7-Allyl-8-oxoguanosine; RWJ 21757, 7-Allyl-2-amino-9-(3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-7,9-dihydro-1H-purine-6,8-dione. Grades: Highly Purified. CAS No. 121288-39-9. Pack Sizes: 5mg, 25mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences.
Worldwide
Loxoribine
It is a small-molecule immunostimulant, toll-like receptor 7 (TLR7) agonist, TLR7 ligand and antitumor agent. Synonyms: 7,8-Dihydro-8-oxo-7-allyl-guanosine; RWJ-21757; RWJ 21757; RWJ21757; 7-Allyl-8-oxoguanosine; Loxoribina; 7-Allyl-7,8-dihydro-8-oxoguanosine; 7-Allyl-2-amino-9-beta-D-ribofuranosylpurine-6,8(1H,9H)-dione. Grades: ≥95%. CAS No. 121288-39-9. Molecular formula: C13H17N5O6. Mole weight: 339.30.
LP 12 hydrochloride
LP 12 hydrochloride is a 5-HT7 receptor agonist. It can induce relaxation of substance P-induced contractions in guinea pig ileum with EC50 value of 1.77 μM. Synonyms: LP 12 hydrochloride; LP12 hydrochloride; LP-12 hydrochloride; 4-(2-Diphenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 1185136-22-4. Molecular formula: C32H39N3O.HCl. Mole weight: 518.13.
LP-184
LP-184 (compound 6), an acylfulvene analog, inhibits tumor growth. LP-184 has potent anti-cancer activity in the ovarian, colon, prostate and pancreatic cell lines. (patent WO2007019308A2). Uses: Scientific research. Group: Signaling pathways. CAS No. 924835-67-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-139453.
LP1A
LP1A is an antibacterial peptide isolated from Manduca sexta. Synonyms: Gln-Arg-Phe-Ser-Gln-Pro-Thr-Phe-Lys-Leu-Pro-Gln-Gly-Arg-Leu-Thr-Leu-Ser-Arg-Lys-Phe. Grades: 95.8%. Molecular formula: C116H187N35O29. Mole weight: 2535.98.
LP 20 hydrochloride
LP 20 hydrochloride is a ligand of the 5-HT7 receptor. It shows agonist and antagonist activity. Synonyms: LP 20 hydrochloride; LP20 hydrochloride; LP-20 hydrochloride; 1-(4'-Methoxy[1,1-biphenyl]-2-yl)piperazine hydrochloride. Grades: ≥98% by HPLC. CAS No. 1386928-34-2. Molecular formula: C17H20N2O.HCl. Mole weight: 304.81.
LP-261
LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest. Screening in the NCI60 cancer cell lines resulted in a mean GI50 of approximately 100 nM. LP-261 is a very potent inhibitor of angiogenesis, preventing microvessel outgrowth in the rat aortic ring assay and HUVEC cell proliferation at nanomolar concentrations. Complete inhibition of tumor growth was achieved in the PC3 xenograft model and shown to be schedule dependent. Excellent inhibition of tumor growth in the SW620 model was observed, comparable with paclitaxel. Combining oral, low dose LP-261 with bevacizumab led to significantly improved tumor inhibition. Oral LP-261 is very effective at inhibiting tumor growth in multiple mouse xenograft models and is well tolerated. Synonyms: LP261; LP 261. Grades: 99%. CAS No. 915412-67-8. Molecular formula: C22H19N3O4S. Mole weight: 421.47.
LP 44
LP 44 is a 5-HT7 receptor agonist with Ki value of 0.22 nM that displays selectivity over 5-HT1A and 5-HT2A receptors (200- and > 1000-fold respectively). It induces relaxation of substance P-induced guinea pig ileum contraction with an EC50 value of 2.56 μM. Synonyms: LP-44; LP 44; LP44; 4-[2-(Methylthio)phenyl]-N-(1,2,3,4-tetrahydro-1-naphthalenyl)-1-piperazinehexanamide hydrochloride. Grades: ≥98% by HPLC. CAS No. 824958-12-5. Molecular formula: C27H37N3OS.HCl. Mole weight: 488.13.
LP-44 Hydrochloride
A potent agonist of the 5-HT7 serotonin receptor (Ki= 0.22nM) with good selectivity against other 5-HT receptors (5-HT1A Ki = 52.7nM, 5-HT1B Ki = 60nM). Often used in conjuction with the selective 5-HT7 receptor antagonist, SB-269970. Group: Biochemicals. Grades: Highly Purified. CAS No. 824958-12-5. Pack Sizes: 10mg. Molecular Formula: C??H??ClN?OS. US Biological Life Sciences.
Worldwide
LP-533401
LP-533401 is an inhibitor of tryptophan 5-hydroxylase 1 (Tph1) that suppresses serotonin production in the gut. It prevents the development of osteoporosis in ovariectomized and aged mice. Synonyms: (2S)-2-Amino-3-[4-[2-amino-6-[2,2,2-trifluoro-1-[4-(3-fluorophenyl)phenyl]ethoxy]pyrimidin-4-yl]phenyl]propanoic acid. Grades: ≥98%. CAS No. 945976-43-2. Molecular formula: C27H22F4N4O3. Mole weight: 526.5.
LP-922761
LP-922761 is a potent AAK1 inhibitor (IC50 values are 4.8 and 7.6 nM in enzyme and cell assays, respectively). Synonyms: tert-Butyl (2-((3-(4-carbamoylphenyl)imidazo[1,2-b]pyridazin-6-yl)amino)ethyl)(methyl)carbamate. Grades: ≥98% by HPLC. CAS No. 1454808-95-7. Molecular formula: C21H26N6O3. Mole weight: 410.47.
LP-935509
LP-935509 is a brain penetrant inhibitor of adapter protein-2 associated kinase 1 (AAK1; IC50 value 3.3 nM and 14 nM and 320 nM for the closely related BIKE and GAK enzymes, repsectively). LP-935509 exhibits antinociceptive property in multiple rat models of neuropathic pain, but not acute pain. The antinociception of AAK1 inhibitor can be blocked by α2 adrenergic antagonists. Uses: Antinociceptive agent. Synonyms: LP935509; LP 935509; LP-935509; Isopropyl 4-(3-(2-methoxypyridin-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl)piperazine-1-carboxylate; 4-[3-(2-Methoxy-pyridin-3-yl)-pyrazolo[1,5-a]pyrimidin-5-yl]-piperazine-1-carboxylic acid isopropyl ester. Grades: 99%. CAS No. 1454555-29-3. Molecular formula: C20H24N6O3. Mole weight: 396.44.
LP99
LP99 is the first selective BRD7/9 bromodomain inhibitor. The effect of LP99 on IL-6 expression demonstrates for the first time that a small-molecule BRD7/9 inhibitor may have a similar function and utility to IL-6 neutralizing antibodies, such as tocilizumab, in the treatment of rheumatoid arthritis. Synonyms: N-[(2R,3S)-2-(4-chlorophenyl)-1-(1,4-dimethyl-2-oxoquinolin-7-yl)-6-oxopiperidin-3-yl]-2-methylpropane-1-sulfonamideN-((2R,3S)-2-(4-chlorophenyl)-1-(1,4-dimethyl-2-oxo-1,2-dihydroquinolin-7-yl)-6-oxopiperidin-3-yl)-2-methylpropane-1-sulfonamideN-[(2R,3S)-2-(4-chlorophenyl)-1-(1,4-dimethyl-2-oxo-1,2-dihydroquinolin-7-yl)-6-oxopiperidin-3-yl]-2-methylpropane-1-sulfonamideGTPL8572; GTPL 8572; GTPL-8572; LP99; LP-99; LP 99. Grades: >98%. CAS No. 1808951-93-0. Molecular formula: C26H30ClN3O4S. Mole weight: 516.05.
LP99
LP99, an epigenetic probe, is a potent and selective inhibitor of the BRD7 and BRD9 bromodomains with a K d of 99 nM against BRD9. LP99 disrupts the binding of BRD7 and BRD9 to chromatin in cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1808951-93-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19553.