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| Product | Description | |
|---|---|---|
| LY2886721 | LY2886721 is a potent, selective and orally active beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC50 of 20.3 nM for recombinant human BACE1. LY2886721 is selectivity against cathepsin D, pepsin, and renin, but lacking selectivity against BACE2 (IC50 of 10.2 nM). LY2886721 can across blood-brain barrier and has the potential for Alzheimer's disease treatment[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1262036-50-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13240. |  |
| LY2922470 | LY2922470 Inhibitor. Uses: Scientific use. Product Category: T15810. CAS No. 1423018-12-5. |  |
| LY294002 | LY294002 is a broad-spectrum inhibitor of PI3K with IC 50 s of 0.5, 0.57, and 0.97 μM for PI3Kα , PI3Kδ and PI3Kβ , respectively [1]. LY294002 also inhibits CK2 with an IC 50 of 98 nM [2]. LY294002 is a competitive DNA-PK inhibitor that binds reversibly to the kinase domain of DNA-PK with an IC 50 of 1.4 μM. LY294002 is an apoptosis activator [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 154447-36-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10108. | |
| LY294002 | LY294002 Inhibitor. Uses: Scientific use. Product Category: T2008. CAS No. 154447-36-6. | |
| LY294002 | Potent, cell permeable, highly specific PI(3)K (phosphoinositide 3-kinase) inhibitor. Acts on the ATP-binding site of the enzyme. Antagonizes P-glycoprotein-mediated multidrug resistance. Blocks Akt phosphorylation. Pim-1 kinase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 154447-36-6. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C19H17NO3. US Biological Life Sciences. |  Worldwide |
| LY 294002, 4?-NH? - CAS 942289-87-4 | A cell-permeable LY 294002 4'-amino derivative with enhanced potency against p110?/?/?/?. Group: Fluorescence/luminescence spectroscopy. |  |
| LY 294002 - CAS 154447-36-6 | LY294002, CAS 154447-36-6, is a cell-permeable, potent, reversible, and specific inhibitor of PI 3-kinase ((IC?? = 1.4 μM). Acts on the ATP-binding site. Group: Fluorescence/luminescence spectroscopy. | |
| LY 294002 hydrochloride | LY 294002 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 934389-88-5. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| LY-294,002 hydrochloride | solid, ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| LY294002 hydrochloride | LY294002 hydrochloride is a potent and broad-spectrum PI3K inhibitor, with IC 50 values of 0.5, 0.57, and 0.97 μM for P110α , P110δ and P110β , respectively. LY294002 hydrochloride also inhibits CK2 with an IC 50 of 98 nM. LY294002 hydrochloride can be used for pancreatic cancer research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 934389-88-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10108A. | |
| LY2940094 | LY2940094 (BTRX-246040) is a potent, selective and orally available nociceptin receptor (NOP receptor) antagonist with high affinity (Ki=0.105 nM) and antagonist potency (Kb=0.166 nM). LY2940094 reduces ethanol self-administration in animal models[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BTRX-246040. CAS No. 1307245-86-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-114452. | |
| LY2955303 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| LY 3000328 | LY 3000328 (Z-FL-COCHO) is a potent and selective Cathepsin S (Cat S) inhibitor with IC50s of 7.7 and 1.67 nM for hCat S and mCat S, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Z-FL-COCHO. CAS No. 1373215-15-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-15533. | |
| LY3009120 | LY3009120 (DP-4978) is a pan RAF inhibitor which inhibits BRAF V600E , BRAF WT and CRAF WT with IC 50 s of 5.8, 9.1 and 15 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DP-4978. CAS No. 1454682-72-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12558. | |
| LY3022855 | LY3022855 is a CHO-expressed human antibody that targets CSF1R/M-CSFR/CD115. LY3022855 has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for LY3022855 can refer to Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2305770-44-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990619. | |
| LY 303511 | LY 303511. Group: Biochemicals. Grades: Purified. CAS No. 154447-38-8. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| LY 303511 - CAS 154447-38-8 | A cell-permeable negative control for the PI 3-kinase inhibitor LY 294002. Group: Fluorescence/luminescence spectroscopy. | |
| LY 303511 hydrochloride | LY 303511 hydrochloride is a structural analogue of LY294002. LY303511 does not inhibit PI3K. LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells. LY303511 reversibly blocks K + currents (IC 50 =64.6±9.1 μM) in MIN6 insulinoma cells. Uses: Scientific research. Group: Signaling pathways. CAS No. 2070014-90-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15643A. | |
| LY311727 | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| LY 311727 | LY 311727. Group: Biochemicals. Grades: Purified. CAS No. 164083-84-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| LY3154207 | LY3154207 is a potent, subtype selective, and orally available human dopamine D1 receptor positive allosteric modulator (PAM) with minimal allosteric agonist activity ( EC 50 =3 nM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1638667-79-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-128770. | |
| LY 315920 | LY 315920. Group: Biochemicals. Grades: Purified. CAS No. 172732-68-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| LY3200882 | LY3200882 is a potent, highly selective, ATP-competitive and orally active TGF-β receptor type 1 (ALK5) inhibitor with an IC 50 of 38.2 nM. LY3200882 inhibits various pro-tumorigenic activities and is also used as an immune modulatory agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1898283-02-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103021. | |
| LY 320135 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| LY 320135 | LY 320135. Group: Biochemicals. Grades: Purified. CAS No. 176977-56-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| LY3295668 | LY3295668 (AK-01) is a potent, orally active and highly specific Aurora-A kinase inhibitor, with K i values of 0.8 nM and 1038 nM for AurA and AurB, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AK-01. CAS No. 1919888-06-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114258. | |
| LY 333531 hydrochloride | LY 333531 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 169939-93-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| LY-333,531 hydrochloride | Isozyme selective inhibitor of protein kinase Cbeta (PKCbeta). PKCbetaI and PKCbetaII isozyme inhibitor. Amelioriates diabetic retinopathy, diabetic peripheral neuropathy and diabetic nephropathy. Anti-cancer and anti-angiogenic compound. Suppresses glucose-induced adhesion of human monocytes to endothelial cells. Suppresses ERK1/2 and Akt phosphorylation. Group: Biochemicals. Grades: Highly Purified. CAS No. 169939-93-9. Pack Sizes: 1mg, 5mg. Molecular Formula: C28H28N4O3 HCl. US Biological Life Sciences. | Worldwide |
| LY-333531 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| LY-333,531 hydrochloride (Ruboxistaurin) | An isozyme-selective inhibitor of protein kinase Cb (PKCb). Inhibits both the PKCbI (IC??=4.7 nM) and PKCbII (IC??=5.9nm) isozymes. LY-333,531 is 76- and 61-fold more selective for inhibition of PKCbI and PKCbII over PKCa. Group: Biochemicals. Grades: Highly Purified. CAS No. 169939-93-9. Pack Sizes: 250ug. US Biological Life Sciences. | Worldwide |
| LY-334370 hydrochloride hydrate | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| LY 338979 | LY 338979. Group: Organic light-emitting diode (oled) materials. CAS No. 193281-00-4. Product ID: (2S)-2-[[4-[2-(2-amino-4,6-dioxo-5,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid. Molecular formula: 443.4g/mol. Mole weight: C20H21N5O7. C1=CC (=CC=C1CCC2C3=C (NC2=O)N=C (NC3=O)N)C (=O)NC (CCC (=O)O)C (=O)O. InChI=1S/C20H21N5O7/c21-20-24-15-14 (18 (30)25-20)11 (17 (29)23-15)6-3-9-1-4-10 (5-2-9)16 (28)22-12 (19 (31)32)7-8-13 (26)27/h1-2, 4-5, 11-12H, 3, 6-8H2, (H, 22, 28) (H, 26, 27) (H, 31, 32) (H4, 21, 23, 24, 25, 29, 30)/t11?, 12-/m0/s1. YVRHJHKPTURIID-KIYNQFGBSA-N. |  |
| LY 338979 | LY 338979 is a metabolite of the antifolate Pemetrexed. Group: Biochemicals. Alternative Names: N-[4-[2-(2-Amino-4,5,6,7-tetrahydro-4,6-dioxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid. Grades: Highly Purified. CAS No. 193281-00-4. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| LY 338979 Dimethyl Ester | Protected LY 338979 (L486650), a metabolite of the antifolate Pemetrexed (P219500). Group: Biochemicals. Alternative Names: N-[4-[2-(2-Amino-4,5,6,7-tetrahydro-4,6-dioxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid 1,5-Dimethyl Ester. Grades: Highly Purified. CAS No. 1320346-45-9. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| LY341495 | LY341495 is a metabotropic glutamate receptor (mGluR) antagonist with IC50s of 21 nM, 14 nM, 7.8 ?M, 8.2 ?M, 170 nM, 990 nM, 22 ?M for mGlu2, mGlu3, mGlu1a, mGlu5a, mGlu8, mGlu7, and mGlu4 receptors, respectively[5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 201943-63-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-70059. | |
| LY 341495 disodium salt | LY 341495 disodium salt. Group: Biochemicals. Grades: Purified. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| LY 344864 | LY 344864 is a selective, orally active 5-HT 1F receptor agonist with a K i of 6 nM. LY 344864 is a full agonist producing an effect similar in magnitude to serotonin itself. LY 344864 can cross the blood brain barrier to some extent [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 186544-26-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13788. | |
| LY344864 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| LY-344864 Hydrochloride | LY-344864 Hydrochloride. Group: Biochemicals. Alternative Names: (R)-N-[3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluoro-benzamide Hydrochloride. Grades: Highly Purified. CAS No. 186544-26-3. Pack Sizes: 10mg. Molecular Formula: C21H23ClFN3O, Molecular Weight: 387.88. US Biological Life Sciences. | Worldwide |
| LY 344864 Hydrochloride (5-HT1F Serotonin Receptor Agonist, LY 344864, LY344864, LY-344864) | A selective, brain penetrant, full agonist for the 5-HT1F receptor (pKi = 8.2). It possesses little affinity for the 56 other serotonergic and non-serotonergic neuronal binding sites examined. When examined for its ability to inhibit forskolin-induced cyclic AMP accumulation in cells stably transfected with human 5-HT1F receptors, LY344864 was shown to be a full agonist producing an effect similar in magnitude to serotonin itself. Suitable for both in vitro and in vivo applications and its effects are often reversed with the 5-HT1B/1D antagonist GR 127935. Group: Biochemicals. Grades: Highly Purified. CAS No. 186544-26-3. Pack Sizes: 10mg. Molecular Formula: C??H??FN?O·HCl. US Biological Life Sciences. | Worldwide |
| LY 344864 racemate | LY 344864 racemate is a 5-HT 1F receptor agonist extracted from patent US 5708187 A. Uses: Scientific research. Group: Signaling pathways. CAS No. 186543-64-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13788C. | |
| LY 345899 | LY 345899 Inhibitor. Uses: Scientific use. Product Category: T15827. CAS No. 10538-99-5. | |
| LY 345899 | LY 345899 is a Folate analog and is a methylene tetrahydrofolate dehydrogenase (MTHFD1; DC301) and MTHFD2 inbhibitor with IC50 values of 96 nM and 663 nM, respectively and a Ki of 18 nM for MTHFD1[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 10538-99-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101943. | |
| LY3509754 | LY3509754 (IL-17A inhibitor 1) is a IL-17A inhibitor, with IC50 values of <9.45 nM and 9.3 nM in alphalisa assay and HT-29 cells[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IL-17A inhibitor 1. CAS No. 2452464-73-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-139206. | |
| LY3522348 | KHK-IN-3 (Example 1) is a ketohexokinase ( KHK ) inhibitor. KHK-IN-3 can be used in the study of kidney disease, nonalcoholic steatohepatitis (NASH), diabetes and heart failure. KHK is a rate-limiting enzyme and fructokinase involved in fructose metabolism. KHK catalyzes the phosphorylation of fructose to fructose-1-phosphate (FIP) at the expense of ATP. The lack of feedback inhibition of fructose metabolism triggers the accumulation of downstream intermediates such as lipogenesis, gluconeogenesis, and oxidative phosphorylation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KHK-IN-3. CAS No. 2568608-48-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149987. | |
| LY 354740 | LY 354740. Group: Biochemicals. Alternative Names: (+)-2-Aminobicyclo[3. 1. 0]hexane-2, 6-dicarboxylic acid; (1S, 2S, 5R, 6S)-2-Aminobicyclo[3. 1. 0]hexane-2, 6-dicarboxylic acidLY354740; Eglumegad; Eglumetad; LY354740. Grades: Highly Purified. CAS No. 176199-48-7. Pack Sizes: 2.5mg. Molecular Formula: C8H11NO4, Molecular Weight: 185.18. US Biological Life Sciences. | Worldwide |
| LY 354740 ((1S, 2S, 5R, 6S)-2-Aminobicyclo[3. 1. 0]hexane-2, 6-dicarboxy lic Acid, Eglumegad, Eglumetad) | A highly potent agonist selective for group II (mGluR2/3) receptors (EC50 = 5.1 and 24.3nM at mGlu2 and mGlu3 receptors respectively), No effect at other mGlu subtype receptors (mGlu1a, mGlu5a, mGlu4 or mGlu7) at concentration less than 100uM. Biologically viable admitted orally or systematically. Widely used in studies of addiction, epilepsy, schizophrenia, hyperactivity, and sleep. Group: Biochemicals. Grades: Highly Purified. CAS No. 176199-48-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| LY-354740 hydrate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| LY 364947 | Selective inhibitor of TGF- β type-I receptor (TGF- β RI, TGFR-I, T βR-I, ALK-5) (IC50 values are 59, 400 and 1400nM for TGR- β RI, TGF- β RII and MLK-7K respectively). Inhibits TGF- β-dependent luciferase production in mink lung cells (p3TP lux) and growth in mouse fibroblasts (NIH 3T3) (IC50 values are 47 and 89nM respectively). Suppresses invasion of MDA-MB-231 breast cancer cells in a matrigel invasion assay. Group: Biochemicals. Alternative Names: 4-[3-(2-pyridinyl)-1H-pyrazol-4-yl]quinoline; E 616451; HTS 466284. Grades: Highly Purified. CAS No. 396129-53-6. Pack Sizes: 10mg, 25mg, 50mg. Molecular Formula: C??H??N?, Molecular Weight: 272.3. US Biological Life Sciences. | Worldwide |
| LY-364947 | LY-364947 (HTS466284) is a potent ATP-competitive inhibitor of TGF?R-I with IC50 of 59 nM, and exhibits 7-fold selectivity over TGF?R-II[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HTS466284. CAS No. 396129-53-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13462. | |
| LY-364947 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| LY367385 | LY367385 is a highly selective and potent mGluR1a antagonist. LY367385 has an IC 50 of 8.8 μM for inhibiting of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with >100 μM for mGlu5a. LY367385 has neuroprotective, anticonvulsant and antiepileptic effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 198419-91-9. Pack Sizes: 1 mg. Product ID: HY-107515. | |
| LY-367385 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| LY367385 hydrochloride | LY367385 hydrochloride is a highly selective and potent mGluR1a antagonist. LY367385 hydrochloride has an IC 50 of 8.8 μM for inhibiting of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with >100 μM for mGlu5a. LY367385 hydrochloride has neuroprotective, anticonvulsant and antiepileptic effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2829282-00-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107515A. | |
| LY 367385 Hydrochloride ((S)-(+)-alpha-Amino-4-carboxy-2-methylbenzeneacetic Acid) | A potent antagonist selective for mGlu1a receptors (IC50 = 8.8uM and >100uM for mGlu1a and mGlu5a, respectively). Negligible effect on group II and III mGlu receptors. Frequently used in studies assessing the functional roles of mGlu1a in various brain functions and disorders in which neural transmissions via mGlu1a receptors are involved. Group: Biochemicals. Grades: Highly Purified. CAS No. 98419-91-9(FR. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| LY 368962 Dimethyl Ester | Protected LY 368962 (L486705), a metabolite of the antifolate Pemetrexed (P219500). Group: Biochemicals. Alternative Names: N-[4-[3-(2,6-Diamino-1,4-dihydro-4-oxo-5-pyrimidinyl)-3-oxopropyl]benzoyl]-L-glutamic Acid Dimethyl Ester. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| LY379268 | LY379268 is a potent, selective and brain-penetrant mGlu2/3R agonist with EC50 values of 2.69 nM (mGlu2) and 4.48 nM (mGlu3). LY379268 has no activity on human mGlu 1a, 4a, 5a or 7a receptors. LY379268 has antioxidant and neuroprotective effects[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 191471-52-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103558. | |
| LY 379268 | LY 379268. Group: Biochemicals. Alternative Names: (1R, 4R, 5S, 6R)-4-Amino-2-oxabicyclo[3. 1. 0]hexane-4, 6-dicarboxylic Acid. Grades: Highly Purified. CAS No. 191471-52-0. Pack Sizes: 5mg. Molecular Formula: C7H9NO5, Molecular Weight: 187.15. US Biological Life Sciences. | Worldwide |
| LY 379268 disodium salt | LY 379268 disodium salt. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| LY393558 | LY393558 is a potent and orally active inhibitor of the 5-HT transporter and an antagonist of 5-HT1B and 5-HT1D receptors. LY393558 increase the extracellular levels of 5-HT in mice model frontal cortex. LY393558 can be used for researching depression [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 271780-64-4. Pack Sizes: 1 mg. Product ID: HY-103089. | |
| LY 393558 | LY 393558. Group: Biochemicals. Grades: Purified. CAS No. 271780-64-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| LY404039 | LY404039. Group: Biochemicals. Grades: Highly Purified. CAS No. 635318-55-7. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C7H9NO6S. US Biological Life Sciences. | Worldwide |
| LY404039 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| LY-404,039 ((1R, 4S, 5S, 6S)-4-[[(2S)-2-Amino-4-(methylthio)-1-oxobutyl]amino]-2-thiabicyclo[3. 1. 0]hexane-4, 6-dicarboxylic Acid 2,2-dioxide) | A highly selective and potent agonist for recombinant human mGlu2 and mGlu3 receptors (Ki = 149nM and 92nM, respectively) and for rat neurons mGlu2/3 receptors (Ki = 88nM). Negligible interactions with other mGlu receptors and ionotropic glutamate receptors, glutamate transporter subtypes, monoamine and other receptors. Widely used for investigating neuropsychiatric disorders in animal models and developing potential treatment for human mental disorders, such as schizophrenia. Group: Biochemicals. Grades: Highly Purified. CAS No. 635318-55-7. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| LY 404187 | LY 404187. Group: Biochemicals. Grades: Purified. CAS No. 211311-95-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| LY-404187 | LY-404187 is a potent, selective and centrally active positive allosteric modulator of AMPA receptors , with the EC 50 s of 5.65, 0.15, 1.44, 1.66 and 0.21 μM for GluR1i , GluR2i , GluR2o , GluR3i and GluR4i , respectively. LY-404187 has therapeutic potential in a number of psychiatric disorders and neurodegenerative diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 211311-95-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-13456. | |
| LY-411575 | LY-411575 is a potent ?-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/cell-based), and also inhibits Notch S3 cleavage with an IC50 of 0.39 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 209984-57-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50752. | |
| LY-411575 | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| LY-411575 (LY 411575, LY411575, Semagacestat) | LY-411575 (LY 411575, LY411575, Semagacestat). Group: Biochemicals. Alternative Names: (2S)-2-[[(2S)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]amino]-N-[(7S)-5-methyl-6-oxo-7H-benzo[d][1]benzazepin-7-yl]propanamide. Grades: Highly Purified. CAS No. 209984-57-6. Pack Sizes: 25mg. Molecular Formula: C26H23F2N3O4, Molecular Weight: 479.5. US Biological Life Sciences. | Worldwide |
| LY450139 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
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