A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
recombinant, expressed in E. coli, ?97% (SDS-PAGE), ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy.
MIP-3beta from mouse
recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy.
MIP-3beta human
recombinant, expressed in E. coli, ?99% (SDS-PAGE), ?99% (HPLC). Group: Fluorescence/luminescence spectroscopy.
MIP-3 (CCL23) human
recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
MIP-4 (PARC) human
recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy.
MIP-5/CCL15 human
recombinant, expressed in E. coli, ?97% (SDS-PAGE), ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy.
Mipasetamab
Mipasetamab is an IgG1κ antibody targeting to AXL , a tyrosine kinase receptor and an TAM Receptor. Mipasetamab involves in synthesis of ADCT-601 (Mipasetamab uzoptirine), an AXL-targeted antibody-drug conjugate (ADC). ADCT-601 has anti-tumor activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2361055-48-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99733.
MIPS-521
MIPS-521 is a positive allosteric modulator of the A1R, exhibits analgesic efficacy in rats in vivo through modulation of the increased levels of endogenous adenosine that occur in the spinal cord of rats with neuropathic pain. We also report the structure of the A1R co-bound to adenosine, MIPS521 and a Gi2 heterotrimer, revealing an extrahelical lipid-detergent-facing allosteric binding pocket that involves transmembrane helixes 1, 6 and 7. Molecular dynamics simulations and ligand kinetic binding experiments support a mechanism whereby MIPS521 stabilizes the adenosine-receptor-G protein complex. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MIPS-521; MIPS 521 MIPS521. Product Category: Others. Appearance: Solid powder. CAS No. 1146188-19-3. Molecular formula: C19H10ClF6NOS. Mole weight: 449.8. Purity: >98%. IUPACName: (2-Amino-4-(3,5-bis(trifluoromethyl)phenyl)thien-3-yl)(4-chlorophenyl)methanone. Canonical SMILES: O=C(C1=C(N)SC=C1C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)C3=CC=C(Cl)C=C3. Product ID: ACM1146188193. Alfa Chemistry ISO 9001:2015 Certified.
MIR96-IN-1
MIR96-IN-1, a benzimidazole derivative, could restrain microRNA-96 biogenesis and also be probable to lead to the apoptosis of cancer cells. Uses: Mir96-in-1 could restrain microrna-96 biogenesis and also be probable to lead to the apoptosis of cancer cells. Synonyms: MIR96-IN-1; MIR96 IN 1; MIR96IN1; MIR96 inhibitor 1; MIR96-inhibitor-1; SCHEMBL16451136; CS-5422; HY-15843; CS 5422; HY 15843; CS5422; HY15843. Grades: 98%. CAS No. 1311982-88-3. Molecular formula: C33H48N8O2. Mole weight: 588.79.
MIRA-1
MIRA-1 is a maleimide-derived compound that reactivates the tumor suppressor function of mutant p53. It can induce apoptosis in several human solid tumor cell lines carrying tetracycline-regulated mutant p53 with IC50 value of 10 μM in vitro. Synonyms: NSC19630; NSC-19630; NSC 19630; MIRA-1; MIRA1; MIRA 1; 1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2,5-dione. Grades: ≥98% by HPLC. CAS No. 72835-26-8. Molecular formula: C8H9NO4. Mole weight: 183.16.
MIRA-1
MIRA-1. Group: Biochemicals. Grades: Purified. CAS No. 72835-26-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Mirabegron
Mirabegron (formerly YM-178, trade name Myrbetriq) is a drug for the treatment of overactive bladder. It was developed by Astellas Pharma and was approved in the United States in July 2012. Mirabegron activates the β3 adrenergic receptor in the detrusor muscle in the bladder, which leads to muscle relaxation and an increase in bladder capacity. Uses: Adrenergic beta-3 receptor agonists. Synonyms: YM-178; YM 178; YM178. Grades: 0.99. CAS No. 223673-61-8. Molecular formula: C21H24N4O2S. Mole weight: 396.51.
Mirabegron
Potent bladder relaxant and reagent for diabetes remedy. Group: Biochemicals. Alternative Names: 2-Amino-N- [4- [2- [ [ (2R) -2-hydroxy-2-phenylethyl] amino] ethyl] phenyl] -4-thiazoleacetamide; (2R) -2- (2-Aminothiazol-4-yl) -4'-[2-[ (2-hydroxy-2-phenylethyl) amino]ethyl]acetic Acid Anilide; YM 178. Grades: Highly Purified. CAS No. 223673-61-8. Pack Sizes: 500mg, 1g, 2g, 5g. Molecular Formula: C??H??N?O?S, Molecular Weight: 396.51. US Biological Life Sciences.
Worldwide
Mirabegron
Mirabegron is a selective β 3 -adrenoceptor agonist with EC 50 of 22.4 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: YM178. CAS No. 223673-61-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14773.
Mirabegron
Mirabegron tablets were developed by Astellas Pharmaceuticals, Inc. and launched in Japan on September 16, 2011, and approved by the U.S. Food and Drug Administration (FDA) on June 28, 2012, for the treatment of overactive bladder (OAB) in adults. Mirabella is the first β3-adrenoceptor agonist drug in the class for the treatment of overactive bladder disorder, and its successful launch fills the gap in the treatment of overactive bladder disorder with β-adrenoceptor agonists. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-(4-(2-(2-hydroxy-2-phenylethylamino)ethyl)phenyl)-2-(2-aminothiazol-4-yl)acetamide;YM-178;MIRABEQRON;2-Amino-N-[4-[2-[[(2R)-2-hydroxy-2-phenyl-ethyl]amino]-ethyl]phenyl]-4-thiazoleacetamide;2-(2-amino-1,3-thiazol-4-yl)-N-(4-{2-[(2-hydroxy-2-phenylethyl)amino]ethyl}phenyl)acetamide. Product Category: Heterocyclic Organic Compound. Appearance: Light yellow to yellow solid. CAS No. 223673-61-8. Molecular formula: C21H24N4O2S. Mole weight: 396.506. Density: 1.313. Product ID: ACM223673618. Alfa Chemistry ISO 9001:2015 Certified.
Mirabegron 3N-Oxide
Mirabegron 3N-Oxide is an impurity of Mirabegron (M364900) which is potent bladder relaxant and reagent for diabetes remedy. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2mg. Molecular Formula: C21H24N4O3S, Molecular Weight: 412.51. US Biological Life Sciences.
Worldwide
Mirabegron impurity 002
An impurity of Mirabegron. Mirabegron (formerly YM-178, trade name Myrbetriq) is a drug for the treatment of overactive bladder. It was developed by Astellas Pharma and was approved in the United States in July 2012. Mirabegron activates the β3 adrenergic receptor in the detrusor muscle in the bladder, which leads to muscle relaxation and an increase in bladder capacity. Synonyms: 4-ethoxy-3-methoxybenzonitrile; 81259-56-5; SCHEMBL6944897; MFCD02256107; AKOS000198357; 4-ETHOXY-3-METHOXY-BENZONITRILE; CS-0319395; Z54794538. Grades: 95%. CAS No. 81259-56-5. Molecular formula: C10H11NO2. Mole weight: 177.20.
Mirabegron impurity 003
An impurity of Mirabegron. Mirabegron (formerly YM-178, trade name Myrbetriq) is a drug for the treatment of overactive bladder. It was developed by Astellas Pharma and was approved in the United States in July 2012. Mirabegron activates the β3 adrenergic receptor in the detrusor muscle in the bladder, which leads to muscle relaxation and an increase in bladder capacity. Synonyms: 4-fluoro-N-methyl-2-nitrobenzamide; SCHEMBL1668405; YLTRKOOKMIYJDB-UHFFFAOYSA-N; 1018983-85-1. Grades: 95%. CAS No. 1018983-85-1. Molecular formula: C8H7FN2O3. Mole weight: 198.15.
Mirabegron Impurity 10
Mirabegron Impurity 10 is an impurity in commercial preparation of Mirabegron. Synonyms: N-(4-(2-amino-2-oxoethyl)thiazol-2-yl)-2-(2-aminothiazol-4-yl)acetamide. Grades: > 95%. Molecular formula: C10H11N5O2S2. Mole weight: 297.36.
Mirabegron Impurity 11
Mirabegron Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1684452-85-4. Molecular formula: C21H24N4O2S. Mole weight: 396.51. Catalog: APB1684452854.
(S)-Mirabegron is an impurity of Mirabegron. Mirabegron is a potent bladder relaxant and reagent for diabetes remedy. Synonyms: (S) -2- (2-Aminothiazol-4-yl) -N- (4- (2- ( (2-hydroxy-2-phenylethyl) amino) ethyl) phenyl) acetamide. Grades: > 95%. CAS No. 1796931-48-0. Molecular formula: C21H24N4O2S. Mole weight: 396.51.
Di(2-Amino-4-thiazolyl)acetyl Mirabegron is an impurity of mirabegron. Mirabegron is a potent bladder relaxant and reagent for diabetes remedy. Synonyms: Di(2-Amino-4-thiazolyl)acetyl Mirabegron; (R)-2-(2-Aminothiazol-4-yl)-N-(4-(2-(2-(2-(2-aminothiazol-4-yl)acetamido)thiazol-4-yl)acetamido)phenethyl)-N-(2-hydroxy-2-phenylethyl)acetamide. Grades: > 95%. Molecular formula: C31H32N8O4S3. Mole weight: 676.83.
Mirabegron Impurity 34
Mirabegron Impurity 34. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1684452-84-3. Molecular formula: C31H32N8O4S3. Mole weight: 676.83. Catalog: APB1684452843.
Mirabegron Impurity 36
Mirabegron Impurity 36. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1684453-05-1. Molecular formula: C21H22N4O3S. Mole weight: 410.49. Catalog: APB1684453051.
Mirabegron Impurity 4
Mirabegron Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1684452-83-2. Molecular formula: C26H28N6O3S2. Mole weight: 536.67. Catalog: APB1684452832.
Mirabegron Impurity 4
Mirabegron Impurity 4 is an impurity of mirabegron. Mirabegron is a potent bladder relaxant and reagent for diabetes remedy. Synonyms: N-(2-Amino-4-thiazolyl)acetyl Mirabegron; (R)-2-(2-Aminothiazol-4-yl)-N-(4-(2-(2-aminothiazol-4-yl)acetamido)phenethyl)-N-(2-hydroxy-2-phenylethyl)acetamide. Grades: > 95%. CAS No. 1684452-83-2. Molecular formula: C26H28N6O3S2. Mole weight: 536.67.
Mirabegron Impurity 42
Mirabegron Impurity 42. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106760-65-0. Molecular formula: C16H19NO. Mole weight: 241.33. Catalog: APB106760650.
Mirabegron Impurity 5
2-[[2-2(2-Amino-4-thiazolyl)acetyl]amino]-4-thiazoleacetic Acid is an impurity of mirabegron. Mirabegron is a potent bladder relaxant and reagent for diabetes remedy. Synonyms: 2-[[2-2(2-Amino-4-thiazolyl)acetyl]amino]-4-thiazoleacetic Acid; 2-(2-(2-(2-Aminothiazol-4-yl)acetamido)thiazol-4-yl)acetic Acid. Grades: > 95%. Molecular formula: C10H10N4O3S2. Mole weight: 298.34.
Mirabegron Impurity 6
(R)-2-((4-Aminophenethyl)amino)-1-phenylethanol is an intermediate in the synthesis of Mirabegron related compounds. Synonyms: (R)-2-((4-Aminophenethyl)amino)-1-phenylethanol; (αR)-α-[[[2-(4-aminophenyl)ethyl]amino]methyl]-benzenemethanol. Grades: > 95%. CAS No. 391901-45-4. Molecular formula: C16H20N2O. Mole weight: 256.34.
Mirabegron Impurity 8 2HCl
meta-Mirabegron is an isomer of Mirabegron, a potent bladder relaxant and reagent for diabetes remedy. Synonyms: meta-Mirabegron dihydrochloride; 2-Amino-N-[3-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-4-thiazoleacetamide dihydrochloride. Grades: > 95%. Molecular formula: C21H24N4O2S.2HCl. Mole weight: 469.43.
Mirabegron Impurity 8 HCl
Mirabegron Impurity 8 HCl. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1684452-81-0. Molecular formula: C21H24N4O2S. Mole weight: 396.51. Catalog: APB1684452810.
Mirabegron Impurity 9
Mirabegron Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1684452-80-9. Molecular formula: C21H24N4O2S. Mole weight: 396.51. Catalog: APB1684452809.
Mirabegron M12 is a metabolite of Mirabegron. Synonyms: (2S,3S,4S,5R,6S)-6-(((4-(2-(2-aminothiazol-4-yl)acetamido)phenethyl)(2-oxo-2-phenylethyl)carbamoyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Grades: > 95%. Molecular formula: C28H30N4O10S. Mole weight: 614.64.
Mirabegron M13 (YM-538859)
Mirabegron N-Carbamoylglucuronide is a metabolite of Mirabegron. Synonyms: Mirabegron N-Carbamoylglucuronide; β-D-Glucopyranuronic Acid 1-[N-[2-[4-[[2-(2-Amino-4-thiazolyl)acetyl]amino]phenyl]ethyl]-N-[(2R)-2-hydroxy-2-phenylethyl]carbamate]. Grades: > 95%. CAS No. 1365244-67-2. Molecular formula: C28H32N4O10S. Mole weight: 616.64.
Mirabegron M14 (YM-554028)
Mirabegron O-Glucuronide is a metabolite of Mirabegron. Synonyms: Mirabegron O-Glucuronide; (1R) -2-[[2-[4-[[2- (2-Amino-4-thiazolyl) acetyl]amino]phenyl]ethyl]amino]-1-phenylethyl-β -D-glucopyranosiduronic Acid. Grades: > 95%. CAS No. 1365244-65-0. Molecular formula: C27H32N4O8S. Mole weight: 572.63.
Mirabegron M15 (YM-9636324)
Mirabegron M15 is a glucuronide metabolite of Mirabegron. Synonyms: (2S,3S,4S,5R,6S)-6-(((4-(2-(2-aminothiazol-4-yl)acetamido)phenethyl)((R)-2-hydroxy-2-phenylethyl)amino)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Grades: > 95%. Molecular formula: C27H32N4O9S. Mole weight: 588.64.
Mirabegron M17
Mirabegron M17 is a Metabolite of Mirabegron. Synonyms: (2S,3S,4S,5R,6S)-6-(2-amino-5-(2-((2-hydroxy-2-phenylethyl)amino)ethyl)phenoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Grades: > 95%. Molecular formula: C22H28N2O8. Mole weight: 448.48.
Mirabegron M5 (YM-538852)
N-[4-[2-[[(2R)-2-Hydroxy-2-phenylethyl]amino]ethyl]phenyl]-acetamide is a metabolite of Mirabegron which is a potent bladder relaxant and reagent for diabetes remedy. Synonyms: N-[4-[2-[[(2R)-2-Hydroxy-2-phenylethyl]amino]ethyl]phenyl]-acetamide. Grades: > 95%. CAS No. 1365244-63-8. Molecular formula: C18H22N2O2. Mole weight: 298.38.
Mirabegron M8 (YM-538853)
Mirabegron M8 is a metabolite of Mirabegron. Synonyms: 2-(4-(2-(2-aminothiazol-4-yl)acetamido)phenyl)acetic acid; AGN-PC-0ETBKI; AKOS012094767; 2-[4-[[2-(2-amino-1,3-thiazol-4-yl)acetyl]amino]phenyl]acetic acid. Grades: > 95%. Molecular formula: C13H13N3O3S. Mole weight: 291.33.
Miraculin is a taste improver, which is a glycoprotein extracted from the fruit of Syssepalum dulcificum. CAS No. 198694-37-0. Molecular formula: C88H146N26O34. Mole weight: 2112.28.
Miransertib (ARQ-092) is a potent, orally active, selective and allosteric Akt inhibitor with IC 50 s of 2.7 nM, 14 nM and 8.1 nM for Akt1 , Akt2 , Akt3 , respectively. Miransertib is also a potent the AKT1-E17K mutant protein inhibitor and has the potential for PI3K/AKT-driven tumors and Proteus syndrome research [1]. Miransertib is effective against Leishmania [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARQ-092. CAS No. 1313881-70-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19719.
Miransertib is an orally bioavailable and selective AKT pathway inhibitor that suppresses AKT1, 2, 3 isoforms. It binds to both the active and inactive forms of AKT. Miransertib inhibits PIK3CA/AKT1 mutant dependent kinase signaling and exhibits antitumor activity. Synonyms: Miransertib; ARQ 092 HCl; Miransertib HCl; 3-[3-[4-(1-aminocyclobutyl)phenyl]-5-phenylimidazo[4,5-b]pyridin-2-yl]pyridin-2-amine hydrochloride. CAS No. 1313883-00-9. Molecular formula: C27H25ClN6. Mole weight: 468.98.
Miransertib hydrochloride
Miransertib hydrochloride (ARQ-092 hydrochloride) is a potent, orally active, selective and allosteric Akt inhibitor with IC 50 s of 2.7 nM, 14 nM and 8.1 nM for Akt1 , Akt2 , Akt3 , respectively. Miransertib hydrochloride is also a potent the AKT1-E17K mutant protein inhibitor and has the potential for PI3K/AKT-driven tumors and Proteus syndrome research [1]. Miransertib hydrochloride is effective against Leishmania [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARQ-092 hydrochloride. CAS No. 1313883-00-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19719A.
Mirdametinib (PD0325901) is an orally active, selective and non-ATP-competitive MEK inhibitor with an IC 50 of 0.33 nM. Mirdametinib exhibits a K i app of 1 nM against activated MEK1 and MEK2. Mirdametinib suppresses the expression of p-ERK1/2 and induces apoptosis. Mirdametinib has anti-cancer activity for a broad spectrum of human tumor xenografts [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD0325901; PD325901. CAS No. 391210-10-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10254.
Mirex (Dechlorane 4070)
An insecticide for fire ants. Formerly used as a fire retardant for plastics, rubber, paint, paper, electric goods. Reasonably anticipated to be a human carcinogen. Group: Biochemicals. Alternative Names: 1, 1a, 2, 2, 3, 3a, 4, 5, 5, 5a, 5b, 6-Dodecachlorooctahydro-1, 3, 4-metheno-1H-cyclobuta [cd]pentalene; Dechlorane; Dodecachlor; NSC 124102; NSC 26107; NSC 37656; Paramex; Dodecachlorooctahydro-1, 3, 4-metheno-2H-cyclobuta [cd]pentalene; Perchloropentacyclo[5. 3. 0. 02, 6. 03, 9. 04, 8]decane. Grades: Highly Purified. CAS No. 2385-85-5. Pack Sizes: 10mg. US Biological Life Sciences.
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Miridesap
Miridesap is a ligand for serum amyloid P component ( SAP ) and intends to inhibit and dissociate SAP binding to amyloid fibrils and tangles. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CPHPC; Ro63-8695; GSK2315698. CAS No. 224624-80-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101861.
Mirificin
Mirificin. Group: Biochemicals. Alternative Names: Puerarin-6''-O-beta-D-Apiofuranosyl. Grades: Plant Grade. CAS No. 103654-50-8. Pack Sizes: 20mg. Molecular Formula: C26H28O13, Molecular Weight: 548.493. US Biological Life Sciences.
Worldwide
Mirikizumab
Mirikizumab (LY3074828) is a humanized IgG4 monoclonal antibody that targets the p19 subunit of interleukin 23 ( IL-23 ). Mirikizumab binds to human and monkey IL-23 with high affinity, with K d values of 21 pM and 55 pM, respectively. By inhibiting the binding of IL-23 to IL-23R , Mirikizumab modulates the immune response and holds potential for research in ulcerative colitis and Crohn's disease [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LY-3074828. CAS No. 1884201-71-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99737.