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Mirabegron Impurity 43. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1603-91-4. Molecular Formula: C4H6N2S. Mole Weight: 114.17. Catalog: APB1603914.
Mirabegron Impurity 5
2-[[2-2(2-Amino-4-thiazolyl)acetyl]amino]-4-thiazoleacetic Acid is an impurity of mirabegron. Mirabegron is a potent bladder relaxant and reagent for diabetes remedy. Synonyms: 2-[[2-2(2-Amino-4-thiazolyl)acetyl]amino]-4-thiazoleacetic Acid; 2-(2-(2-(2-Aminothiazol-4-yl)acetamido)thiazol-4-yl)acetic Acid. Grades: > 95%. Molecular formula: C10H10N4O3S2. Mole weight: 298.34.
Mirabegron Impurity 54
Mirabegron Impurity 54. Uses: For analytical and research use. Group: Impurity standards. CAS No. 521284-19-5. Molecular Formula: C16H16N2O4. Mole Weight: 300.31. Catalog: APB521284195.
Mirabegron Impurity 56
Mirabegron Impurity 56. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1627515-83-6. Molecular Formula: C16H18N2O2. Mole Weight: 270.33. Catalog: APB1627515836.
Mirabegron Impurity 6
(R)-2-((4-Aminophenethyl)amino)-1-phenylethanol is an intermediate in the synthesis of Mirabegron related compounds. Synonyms: (R)-2-((4-Aminophenethyl)amino)-1-phenylethanol; (αR)-α-[[[2-(4-aminophenyl)ethyl]amino]methyl]-benzenemethanol. Grades: > 95%. CAS No. 391901-45-4. Molecular formula: C16H20N2O. Mole weight: 256.34.
Mirabegron Impurity 6
Mirabegron Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 391901-45-4. Molecular Formula: C16H20N2O. Mole Weight: 256.35. Catalog: APB391901454.
Mirabegron Impurity 60
Mirabegron Impurity 60. Uses: For analytical and research use. Group: Impurity standards. CAS No. 763911-98-4. Molecular Formula: C21H24N4O3S. Mole Weight: 412.51. Catalog: APB763911984.
Mirabegron Impurity 64
Mirabegron Impurity 64. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2416733-26-9. Molecular Formula: C23H25N5O2S. Mole Weight: 435.55. Catalog: APB2416733269.
Mirabegron Impurity 65
Mirabegron Impurity 65. Uses: For analytical and research use. Group: Impurity standards. CAS No. 521284-22-0. Molecular Formula: C16H21ClN2O. Mole Weight: 292.81. Catalog: APB521284220.
Mirabegron Impurity 8 2HCl
meta-Mirabegron is an isomer of Mirabegron, a potent bladder relaxant and reagent for diabetes remedy. Synonyms: meta-Mirabegron dihydrochloride; 2-Amino-N-[3-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-4-thiazoleacetamide dihydrochloride. Grades: > 95%. Molecular formula: C21H24N4O2S.2HCl. Mole weight: 469.43.
Mirabegron Impurity 8 HCl
Mirabegron Impurity 8 HCl. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1684452-81-0. Molecular Formula: C21H24N4O2S. Mole Weight: 396.51. Catalog: APB1684452810.
Mirabegron Impurity 9
Mirabegron Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1684452-80-9. Molecular Formula: C21H24N4O2S. Mole Weight: 396.51. Catalog: APB1684452809.
Mirabegron M12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1365244-66-1. Molecular Formula: C28H30N4O10S. Mole Weight: 614.63. Catalog: APB1365244661.
Mirabegron M12 (YM-538858)
Mirabegron M12 is a metabolite of Mirabegron. Synonyms: (2S,3S,4S,5R,6S)-6-(((4-(2-(2-aminothiazol-4-yl)acetamido)phenethyl)(2-oxo-2-phenylethyl)carbamoyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Grades: > 95%. Molecular formula: C28H30N4O10S. Mole weight: 614.64.
Mirabegron M13
Mirabegron M13. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1365244-67-2. Molecular Formula: C28H32N4O10S. Mole Weight: 616.64. Catalog: APB1365244672.
Mirabegron M13 (YM-538859)
Mirabegron N-Carbamoylglucuronide is a metabolite of Mirabegron. Synonyms: Mirabegron N-Carbamoylglucuronide; β-D-Glucopyranuronic Acid 1-[N-[2-[4-[[2-(2-Amino-4-thiazolyl)acetyl]amino]phenyl]ethyl]-N-[(2R)-2-hydroxy-2-phenylethyl]carbamate]. Grades: > 95%. CAS No. 1365244-67-2. Molecular formula: C28H32N4O10S. Mole weight: 616.64.
Mirabegron M14
Mirabegron M14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1365244-68-3. Molecular Formula: C27H32N4O8S. Mole Weight: 572.63. Catalog: APB1365244683.
Mirabegron M14 (YM-554028)
Mirabegron O-Glucuronide is a metabolite of Mirabegron. Synonyms: Mirabegron O-Glucuronide; (1R) -2-[[2-[4-[[2- (2-Amino-4-thiazolyl) acetyl]amino]phenyl]ethyl]amino]-1-phenylethyl-β -D-glucopyranosiduronic Acid. Grades: > 95%. CAS No. 1365244-65-0. Molecular formula: C27H32N4O8S. Mole weight: 572.63.
Mirabegron M15
Mirabegron M15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1365244-69-4. Molecular Formula: C27H32N4O9S. Mole Weight: 588.63. Catalog: APB1365244694.
Mirabegron M15 (YM-9636324)
Mirabegron M15 is a glucuronide metabolite of Mirabegron. Synonyms: (2S,3S,4S,5R,6S)-6-(((4-(2-(2-aminothiazol-4-yl)acetamido)phenethyl)((R)-2-hydroxy-2-phenylethyl)amino)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Grades: > 95%. Molecular formula: C27H32N4O9S. Mole weight: 588.64.
Mirabegron M17
Mirabegron M17 is a Metabolite of Mirabegron. Synonyms: (2S,3S,4S,5R,6S)-6-(2-amino-5-(2-((2-hydroxy-2-phenylethyl)amino)ethyl)phenoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Grades: > 95%. Molecular formula: C22H28N2O8. Mole weight: 448.48.
Mirabegron M5
Mirabegron M5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1365244-63-8. Molecular Formula: C18H22N2O2. Mole Weight: 298.39. Catalog: APB1365244638.
Mirabegron M5 (YM-538852)
N-[4-[2-[[(2R)-2-Hydroxy-2-phenylethyl]amino]ethyl]phenyl]-acetamide is a metabolite of Mirabegron which is a potent bladder relaxant and reagent for diabetes remedy. Synonyms: N-[4-[2-[[(2R)-2-Hydroxy-2-phenylethyl]amino]ethyl]phenyl]-acetamide. Grades: > 95%. CAS No. 1365244-63-8. Molecular formula: C18H22N2O2. Mole weight: 298.38.
Mirabegron M8
Mirabegron M8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1365244-64-9. Molecular Formula: C13H13N3O3S. Mole Weight: 291.33. Catalog: APB1365244649.
Mirabegron M8 (YM-538853)
Mirabegron M8 is a metabolite of Mirabegron. Synonyms: 2-(4-(2-(2-aminothiazol-4-yl)acetamido)phenyl)acetic acid; AGN-PC-0ETBKI; AKOS012094767; 2-[4-[[2-(2-amino-1,3-thiazol-4-yl)acetyl]amino]phenyl]acetic acid. Grades: > 95%. Molecular formula: C13H13N3O3S. Mole weight: 291.33.
Mirabegron M9
Mirabegron M9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 18699-02-0. Molecular Formula: C10H11NO3. Mole Weight: 193.2. Catalog: APB18699020.
Mirabellon. Uses: For analytical and research use. Group: Impurity standards. CAS No. 223673-61-8. Molecular Formula: C21H24N4O2S. Mole Weight: 396.51. Catalog: APB223673618.
Miraculin (1-20)
Miraculin is a taste improver, which is a glycoprotein extracted from the fruit of Syssepalum dulcificum. CAS No. 198694-37-0. Molecular formula: C88H146N26O34. Mole weight: 2112.28.
Miransertib (ARQ-092) is a potent, orally active, selective and allosteric Akt inhibitor with IC 50 s of 2.7 nM, 14 nM and 8.1 nM for Akt1 , Akt2 , Akt3 , respectively. Miransertib is also a potent the AKT1-E17K mutant protein inhibitor and has the potential for PI3K/AKT-driven tumors and Proteus syndrome research [1]. Miransertib is effective against Leishmania [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARQ-092. CAS No. 1313881-70-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19719.
Miransertib hydrochloride
Miransertib hydrochloride (ARQ-092 hydrochloride) is a potent, orally active, selective and allosteric Akt inhibitor with IC 50 s of 2.7 nM, 14 nM and 8.1 nM for Akt1 , Akt2 , Akt3 , respectively. Miransertib hydrochloride is also a potent the AKT1-E17K mutant protein inhibitor and has the potential for PI3K/AKT-driven tumors and Proteus syndrome research [1]. Miransertib hydrochloride is effective against Leishmania [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARQ-092 hydrochloride. CAS No. 1313883-00-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19719A.
Miransertib hydrochloride
Miransertib is an orally bioavailable and selective AKT pathway inhibitor that suppresses AKT1, 2, 3 isoforms. It binds to both the active and inactive forms of AKT. Miransertib inhibits PIK3CA/AKT1 mutant dependent kinase signaling and exhibits antitumor activity. Synonyms: Miransertib; ARQ 092 HCl; Miransertib HCl; 3-[3-[4-(1-aminocyclobutyl)phenyl]-5-phenylimidazo[4,5-b]pyridin-2-yl]pyridin-2-amine hydrochloride. CAS No. 1313883-00-9. Molecular formula: C27H25ClN6. Mole weight: 468.98.
Mirdametinib (PD0325901) is an orally active, selective and non-ATP-competitive MEK inhibitor with an IC 50 of 0.33 nM. Mirdametinib exhibits a K i app of 1 nM against activated MEK1 and MEK2. Mirdametinib suppresses the expression of p-ERK1/2 and induces apoptosis. Mirdametinib has anti-cancer activity for a broad spectrum of human tumor xenografts [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD0325901; PD325901. CAS No. 391210-10-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10254.
Mirex (Dechlorane 4070)
An insecticide for fire ants. Formerly used as a fire retardant for plastics, rubber, paint, paper, electric goods. Reasonably anticipated to be a human carcinogen. Group: Biochemicals. Alternative Names: 1, 1a, 2, 2, 3, 3a, 4, 5, 5, 5a, 5b, 6-Dodecachlorooctahydro-1, 3, 4-metheno-1H-cyclobuta [cd]pentalene; Dechlorane; Dodecachlor; NSC 124102; NSC 26107; NSC 37656; Paramex; Dodecachlorooctahydro-1, 3, 4-metheno-2H-cyclobuta [cd]pentalene; Perchloropentacyclo[5. 3. 0. 02, 6. 03, 9. 04, 8]decane. Grades: Highly Purified. CAS No. 2385-85-5. Pack Sizes: 10mg. US Biological Life Sciences.
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Miridesap
Miridesap is a ligand for serum amyloid P component ( SAP ) and intends to inhibit and dissociate SAP binding to amyloid fibrils and tangles. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CPHPC; Ro63-8695; GSK2315698. CAS No. 224624-80-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101861.
Mirificin
Mirificin. Group: Biochemicals. Alternative Names: Puerarin-6''-O-beta-D-Apiofuranosyl. Grades: Plant Grade. CAS No. 103654-50-8. Pack Sizes: 20mg. Molecular Formula: C26H28O13, Molecular Weight: 548.493. US Biological Life Sciences.
Worldwide
Mirikizumab
Mirikizumab (LY3074828) is a humanized IgG4 monoclonal antibody that targets the p19 subunit of interleukin 23 ( IL-23 ). Mirikizumab binds to human and monkey IL-23 with high affinity, with K d values of 21 pM and 55 pM, respectively. By inhibiting the binding of IL-23 to IL-23R , Mirikizumab modulates the immune response and holds potential for research in ulcerative colitis and Crohn's disease [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LY-3074828. CAS No. 1884201-71-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99737.
Mirin
Mirin is a potent Mre11-Rad50-Nbs1 (MRN) complex inhibitor. Mirin prevents MRN-dependent activation of ATM (IC 50 =12 μM) without affecting ATM protein kinase activity, and it inhibits Mre11-associated exonuclease activity. Mirin abolishes the G2/M checkpoint and homology-dependent repair in mammalian cells. Mirin prevents ATM activation in response to DNA double-strand breaks (DSBs) and blocks homology-directed repair (HDR) in mammalian cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 299953-00-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-117693.
Mirin
Mirin is an MRN-ATM pathway inhibitor, inhibiting MRN-dependent activation of ATM without affecting ATM protein kinase activity and Mre11-associated exonuclease activity. Mirin also inhibits the G2/M checkpoint and homology-dependent repair in mammalian cells. Synonyms: 2-amino-5-[(4-hydroxyphenyl)methylidene]-1,3-thiazol-4-one. Grades: ≥95%. CAS No. 299953-00-7. Molecular formula: C10H8N2O2S. Mole weight: 220.3.
Mirin
Mirin. Group: Biochemicals. Grades: Purified. CAS No. 1198097-97-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Miriplatin
Miriplatin (SM-11355) is a chemotherapy agent which belongs to the class of alkylating agents. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SM-11355. CAS No. 141977-79-9. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16325A.
Miriplatin hydrate
Miriplatin (MPT) is a novel platinum complex used in TACE that shows promise for the treatment of hepatocellular carcinoma (HCC). Miriplatin is a lipophilic platinum complex that can be easily suspended in Lipiodol and gradually releases active platinum compounds in tumor tissue. Miriplatin is less severe toxicity profile compared to other platinum anticancer agents. Synonyms: Miripla; Miriplatin; SM 11355; SM11355; SM-11355; MTP. Grades: >98%. CAS No. 250159-48-9. Molecular formula: C34H70N2O5Pt. Mole weight: 782.01.
Miriquidic acid is a substance isolated from Lecidea lilienstroemii and Lecidea leucophaea. CAS No. 35578-70-2. Molecular formula: C25H30O8. Mole weight: 458.5.
Mirisetron maleate
Mirisetron maleate, an oxoquinoline derivative, has been found to be a 5-HT3 receptor antagonist that could probably be effective against anxiety disorders and sleep disorders. It has been already discontinued by Wyeth. Synonyms: MIRISETRON MALEATE; 148611-75-0; UNII-0B4615FL1S; Mirisetron maleate (USAN); AC1O5KJ1; SCHEMBL121861; (Z)-but-2-enedioic acid;1-cyclohexyl-N-[(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]-4-oxoquinoline-3-carboxamide. Grades: 98%. CAS No. 148611-75-0. Molecular formula: C28H35N3O6. Mole weight: 509.60.
A cell-permeable di hydropyridopyrimidine-carboxamide compound that acts as a potent and reversible inhibitor of Mirk/Dyrk1B and Dyrk1A kinases (IC50 = 68 and 22nM). Exhibits very high selectivity for Mirk/Dyrk1B compared to Abl, Flt3, and MARK1 (64, 56 and 73% inhibition at 10uM, respectively) and a panel of 46 other kinases. Shown to induce activation of caspase-3 and sensitize tumor cells to the action of gemcitabine and cisplatin, possibly by de-stabilizing p27. Preferentially increases cycling in Mirk-elevated quiescent pancreatic cancer cells (SU86.86, Panc1, AsPc1, and SW620 at ~1uM). Also, shown to increase level of superoxides in quiescent pancreatic tumor cells (Panc1, SU86.86, and AsPc1) by blocking SOD2 and SOD3 activities. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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Mirk-IN-1
Mirk-IN-1, a pyrido[2,3-d]pyrimidine derivative, has been found to be a DYRK1A/B inhibitor and probably have antitumor activity through influencing the accumulation and induce the DNA damage and apoptosis of Panc1 in tumor cells. IC50: 68±48/22±8 nM (Dyrk. Uses: Mirk-in-1 has been found to be a dyrk1a/b inhibitor and probably have antitumor activity through influencing the accumulation and induce the dna damage and apoptosis of panc1 in tumor cells. Synonyms: Dyrk1B/1A-IN-9; Dyrk1B inhibitor; 1A-IN-9; Dyrk-1B/1A-IN-9; Dyrk 1B/1A IN 9; Dyrk1B/1A-inhibitor-9; Mirk-IN-1; CHEMBL3094448; SCHEMBL10446906; CQKBSRPVZZLCJE-UHFFFAOYSA-N; BDBM50444379; AKOS025147328; N-[2-chloro-5-[(3-chlorophenyl)methylcarbamoyl]phenyl]-2-methoxy-7-oxo-8H-pyrido[2,3-d]pyrimidine-6-carboxamide. Grades: 98%. CAS No. 1386979-55-0. Molecular formula: C23H17Cl2N5O4. Mole weight: 498.32.
Mirodenafil
Mirodenafil is a newly developed oral phosphodiesterase type 5 (PDE-5) inhibitor developed for the treatment of erectile dysfunction. It significantly improved erectile function and were well tolerated in a representative population of Korean men with broad-spectrum ED of various etiologies and severities. Uses: Phosphodiesterase 5 inhibitors. Synonyms: SK3530; SK-3530; SK 3530; Mirodenafil, trade name Mvix. Grades: >98%. CAS No. 862189-95-5. Molecular formula: C26H37N5O5S. Mole weight: 531.67.
Mirodenafil
Mirodenafil (SK3530) is an orally active, potent, reversible, and selective phosphodiesterase 5 (PDE5) inhibitor. Mirodenafil is a glucocorticoid receptor (GR) modulator Mirodenafil activates the Wnt/β-catenin signaling pathway by downregulating Dkk1 expression. Mirodenafil can be used for the research of erectile dysfunction (ED), Alzheimers disease (AD) and systemic sclerosis (SSc) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SK3530. CAS No. 862189-95-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14930.
Mirodenafil dihydrochloride
Mirodenafil (SK3530) dihydrochloride is an orally active, potent, reversible, and selective phosphodiesterase 5 (PDE5) inhibitor. Mirodenafil dihydrochloride is a glucocorticoid receptor (GR) modulator Mirodenafil dihydrochloride activates the Wnt/β-catenin signaling pathway by downregulating Dkk1 expression. Mirodenafil dihydrochloride can be used for the research of erectile dysfunction (ED), Alzheimers disease (AD) and systemic sclerosis (SSc) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SK-3530 dihydrochloride. CAS No. 862189-96-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14930A.
Mirodenafil dihydrochloride
Mirodenafil dihydrochloride. Group: Biochemicals. Alternative Names: 5-Ethyl-3,5-dihydro-2-[5-[[4-(2-hydroxyethyl)-1-piperazinyl]sulfonyl]-2-propoxyphenyl]-7-propyl-4H-pyrrolo[3,2-d]pyrimidin-4-one hydrochloride. Grades: Highly Purified. CAS No. 862189-96-6. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C26H39Cl2N5O5S. US Biological Life Sciences.
Worldwide
Mirodenafil Dihydrochloride
Mirodenafil dihydrochloride is a newly developed oral phosphodiesterase type 5 (PDE-5) inhibitor developed for the treatment of erectile dysfunction. Synonyms: 5-Ethyl-3,5-dihydro-2-[5-[[4-(2-hydroxyethyl)-1-piperazinyl]sulfonyl]-2-propoxyphenyl]-7-propyl-4H-pyrrolo[3,2-d]pyrimidin-4-one Hydrochloride; 4-[[3-(5-Ethyl-4,5-dihydro-4-oxo-7-propyl-1H-pyrrolo[3,2-d]pyrimidin-2-yl)-4-propoxyphenyl]sulfonyl]-1-piperazineethanol Dihydrochloride; Mirodenafil 2HCl; M-vix; SK 3530 dihydrochloride; SK3530 dihydrochloride; SK-3530 dihydrochloride. Grades: > 98%. CAS No. 862189-96-6. Molecular formula: C26H39Cl2N5O5S. Mole weight: 604.59.
Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium channel complexes in the CNS. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DS5565. CAS No. 1138245-13-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12650.
Mirogabalin
Mirogabalin. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1138245-13-2. Molecular Formula: C12H19NO2. Mole Weight: 209.29. Catalog: APB1138245132.
Mirogabalin
This active molecular is an α2δ-1 ligand being developed for pain associated with diabetic peripheral neuropathy, fibromyalgia, and postherpetic neuralgia which related to related to drugs such as gabapentin and pregabalin. Mirogabalin binds to the α2δ calcium channels (1 and 2) and was estimated to be much more potent than pregabalin. In Nov 2015, a Japanese company named Daiichi Sankyo plans a phase III trial for Postherpetic neuralgia and Neuropathic pain (in patients with diabetic peripheral neuropathy and renal impairment) in Japan. In May 2016, Pharmacokinetics and adverse data from a phase I trial in volunteers presented at the 35th Annual Scientific Meeting of the American Pain Society. Uses: Treatment of diabetic peripheral neuropathic pain. Synonyms: 2-[(1R,5S,6S)-6-(aminomethyl)-3-ethyl-6-bicyclo[3.2.0]hept-3-enyl]acetic acid, DS-5565,CAS#1138245-21-2 ( Mirogabalin besylate). Grades: 98%. CAS No. 1138245-13-2. Molecular formula: C12H19NO2. Mole weight: 209.29.
Mirogabalin besylate
Mirogabalin besylate is a selective and orally available ligand for the α2δ subunit of voltage-gated calcium channels , with K d s of 13.5 nM, 22.7 nM, 27 nM, and 47.6 nM for human α2δ-1, human α2δ-2, rat α2δ-1, and rat α2δ-2, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DS 5565 besylate. CAS No. 1138245-21-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-108006.
Mirogabalin besylate
Mirogabalin besylate is a selective and orally available ligand for the voltage-gated calcium channel α2δ subunit and is being developed for the treatment of pain associated with diabetic peripheral neuropathy, fibromyalgia and post-herpetic neuralgia. Synonyms: DS-5565; DS 5565; DS5565; A-2000700. Grades: 98%. CAS No. 1138245-21-2. Molecular formula: C18H25NO5S. Mole weight: 367.5.