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| Product | Description | |
|---|---|---|
| Misch Metal, 99.0% min. rare earth content | Misch Metal, 99.0% min. rare earth content. Group: Alloys. CAS No. 62379-61-7. Product ID: cerium; lanthanum; neodymium; praseodymium. Molecular formula: 564.17g/mol. Mole weight: CeLaNdPr. [La].[Ce].[Pr].[Nd]. InChI=1S/Ce.La.Nd.Pr. YLENEZYZPLSAAV-UHFFFAOYSA-N. |  |
| Misch Metal, 99.8% min. rare earth content, trapezoidal ingot, dry | Misch Metal, 99.8% min. rare earth content, trapezoidal ingot, dry. Group: Alloys. CAS No. 62379-61-7. Product ID: cerium; lanthanum; neodymium; praseodymium. Molecular formula: 564.17g/mol. Mole weight: CeLaNdPr. [La].[Ce].[Pr].[Nd]. InChI=1S/Ce.La.Nd.Pr. YLENEZYZPLSAAV-UHFFFAOYSA-N. | |
| Mischmetal-nickel alloy | Description General description We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for energy efficiency. Find details here. Application Mischmetal-nickel alloy is a hydrogen storage alloy, which consists of rare earth metals and transition metals. It can be used as an anode material for the formation of nickel-metal hydride batteries. These batteries can further be utilized in hybrid vehicles. Packaging 10 g in glass bottle. Group: Hydrogen storage materials electrode materials. CAS No. 54426-34-5. Mole weight: (Ce,La,Nd,Pr)Ni5. 1S/Co.La.Ni. OPDRIGFSUGVDKR-UHFFFAOYSA-N. | |
| Misgurin | A novel antimicrobial peptide, named misgurin, was isolated and characterized from the loach (mudfish), Misgurnus anguillicaudatus. Misgurin showed a strong antimicrobial activity in vitro against a broad spectrum of microorganisms without significant hemolytic activity and was about 6 times more potent than magainin 2. Molecular formula: C106H189N41O29. Mole weight: 2501.88. |  |
| m-Isobutyl Ibuprofen | An Ibuprofen impurity used in the study of potent noncompetitive interleukin-8 inhibitors. Group: Biochemicals. Alternative Names: α -Methyl-3- (2-methylpropyl) benzeneacetic Acid, α - (3-Isobutylphenyl) propionic Acid; α -Methyl-3- (2-methylpropyl) phenylacetic Acid; 2- (3-Isobutylphenyl) propionic Acid. Grades: Highly Purified. CAS No. 66622-47-7. Pack Sizes: 25mg. US Biological Life Sciences. |  Worldwide |
| Misonidazole | Misonidazole (Ro 7-0582; SR 1354) is a hypoxic tumor cell radiosensitizer [1]. Misonidazole also has antimicrobial effects [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 7-0582; SR 1354. CAS No. 13551-87-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-105061. |  |
| Misonidazole-d3 | 2H Labeled Compounds. Alternative Names: alpha-(Methoxymethyl)-2-nitro-1H-imidazole-1-ethanol-d3; alpha-(Methoxymethyl)-2-nitroimidazole-1-ethanol-d3; 1-(2-Hydroxy-3-methoxypropyl)-2-nitroimidazole-d3; 1-(2-Nitro-1-imidazolyl)-3-methoxy-2-propanol-d3; 2-Nitro-1H-imidazole-1-(3-methoxy-2-propanol)-d3; NSC 261037-d3; Racemic Misonidazole-d3; Ro 7-0582-d3; SR 1354-d3; SRI 1354-d3; alpha-(Methoxy-d3-methyl)-2-nitro-1H-imidazole-1-ethanol. CAS No. 121244-83-5. Molecular formula: C7H8D3N3O4. Mole weight: 204.2. Catalog: ACM121244835. |  |
| Misoprostol | A cytoprotective prostaglandin PGE1 analogue. Group: Biochemicals. Alternative Names: (11α,13E)-(+/-)-11,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic Acid Methyl Ester; Cytotec; Misogon; Misoprostil; SC 29333. Grades: Highly Purified. CAS No. 59122-46-2. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Misoprostol | Misoprostol is a cytoprotective prostaglandin PGE1 analogue. Uses: An effective anti-ulcer agent and also has oxytocic properties. Synonyms: (11α,13E)-(+/-)-11,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic Acid Methyl Ester; Cytotec; Misogon; Misoprostil; SC 29333. Grades: > 95%. CAS No. 59122-46-2. Molecular formula: C22H38O5. Mole weight: 382.53. | |
| Misoprostol, 1% in Cellulose | Misoprostol, 1% in Cellulose. Group: Biochemicals. Alternative Names: (11a,13E)-(+/-)-11,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic acid methyl ester; Cytotec; Misogon. Grades: Highly Purified. CAS No. 59122-46-2. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C22H38O5, Molecular Weight: 382.53. US Biological Life Sciences. | Worldwide |
| Misoprostol acid | Misoprostol Acid is a cytoprotective prostaglandin PGE1 analogue. Synonyms: (11α,13E)-(+/-)-11,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic Acid Methyl Ester; Cytotec; Misogon; Misoprostil; SC 29333. Grades: > 95%. CAS No. 112137-89-0. Molecular formula: C21H36O5. Mole weight: 368.51. | |
| Misoprostol acid (10 mg in 1 mL methyl acetate) | Misoprostol acid (10 mg in 1 mL methyl acetate). Group: Biochemicals. Alternative Names: (11a,13E)-11,16-Dihydroxy-16-methyl-9-oxo-prost-13-en-1-oic acid; Misoprostol free acid; (+/-)-15-Deoxy-(16RS)-16-hydroxy-16-methylprogestaglandin E1. Grades: Highly Purified. CAS No. 112137-89-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C21H36O5. US Biological Life Sciences. | Worldwide |
| Misoprostol-d4 | Labelled Misoprostol, a cytoprotective prostaglandin PGE1 analogue. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Misoprostol EP Impurity A | Misoprostol EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1788085-78-8. Molecular Formula: C22H38O5. Mole Weight: 382.54. Catalog: APB1788085788. |  |
| Misoprostol Impurity 2 | Misoprostol Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 58682-86-3. Molecular Formula: C22H36O4. Mole Weight: 364.53. Catalog: APB58682863. | |
| Misoprostol Impurity 2 (Misoprostol B) | Grades: > 95%. Molecular formula: C22H38O5. Mole weight: 382.55. | |
| Misoprostol Impurity 3 | Grades: > 95%. Molecular formula: C13H20O4. Mole weight: 240.30. | |
| Misoprostol Impurity 4 | Grades: > 95%. Molecular formula: C22H38O5. Mole weight: 382.55. | |
| Misoprostol Impurity (A-Form) | Grades: > 95%. Molecular formula: C22H36O4. Mole weight: 364.53. | |
| Misoprostol Impurity (B-Form) | rac-11-Deoxy-8(12)-dehydro Misoprostol is a Misoprostol impurity. Synonyms: rac-11-Deoxy-8(12)-dehydro Misoprostol; (13E)-(+/-)-16-Hydroxy-16-methyl-9-oxoprosta-8(12),13-dien- 1-oic Acid Methyl Ester; rac-Misoprostol B1. Grades: > 95%. CAS No. 1331639-92-9. Molecular formula: C22H36O4. Mole weight: 364.52. | |
| Mistletoe Extract | Extract obtained from Viscum Album (Mistletoe) plants. Contains 20% extract dissolved in water and glycerin. Has toning, anti-aging and skin-softening properties. Uses: Creams and lotions, especially for irritated skin. Group: Skin actives. CAS No. 7732-18-5 / 56-81-5 / 84929-55-5 / 122-99-6. Appearance: Light to medium amber liquid, characteristic odor. Catalog: CI-SC-0877. | |
| Mitapivat | Mitapivat (AG-348) is an orally active pyruvate kinase allosteric activator. Mitapivat increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes, shows the potential to restore the activity of PK (pyruvate kinase) -deficient glycolytic pathways. Mitapivat can be used in study of PK deficiency [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG-348. CAS No. 1260075-17-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12689. | |
| Mitazalimab | Mitazalimab (ADC-1013; JNJ-64457107) is FcγR-dependent CD40 agonist with tumor-directed activity. Mitazalimab activates antigen-presenting cells, e.g. dendritic cells (DC), to initiate tumor-reactive T cells. Therefore, Mitazalimab induces tumor-specific T cells to infiltrate and kill tumors. Mitazalimab remodels the tumor-infiltrating myeloid microenvironment [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ADC-1013; JNJ-64457107. CAS No. 2055640-86-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99742. | |
| Mithramycin | Mithramycin was the first of the aureolic acid class of antitumor antibiotics isolated from Streptomyces. Mithramycin inhibits transcription and protein synthesis by non-covalent binding with G-C-rich duplex DNA in the presence of magnesium and zinc ions. Mithramycin has also been shown to induce differentiation of leukemic cells accompanied by an early decrease in c-myc expression and selectively inhibit collagen-1 gene expression in human fibroblasts. Group: Biochemicals. Grades: Highly Purified. CAS No. 18378-89-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Mithramycin A | 5mg Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C52H76O24. CAS No. 18378-89-7. Prepack ID 50053396-5mg. Molecular Weight 1085.15. See USA prepack pricing. |  |
| Mithramycin A | Mithramycin A. Group: Biochemicals. Alternative Names: Aureolic acid. Grades: Highly Purified. CAS No. 18378-89-7. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C52H76O24. US Biological Life Sciences. | Worldwide |
| Mitiglinide | Heterocyclic Organic Compound. Alternative Names: 4-Chloro-2-(3,4-dichlorophenyl)-5-((6-iodo-3-pyridinyl)methoxy)-3(2H)-pyridazinone; 3(2H)-Pyridazinone,4-chloro-2-(3,4-dichlorophenyl)-5-((6-iodo-3-pyridinyl)methoxy). CAS No. 122322-18-7. Molecular formula: C16H9Cl3IN3O2. Mole weight: 508.525. Purity: 0.96. IUPACName: 4-chloro-2-(3,4-dichlorophenyl)-5-[(6-iodopyridin-3-yl)methoxy]pyridaz. Density: 1.85g/cm³. Catalog: ACM122322187. | |
| Mitiglinide | Mitiglinide is a succinic acid derivative with hypoglycemic activity. It belongs to the meglitinide class of blood glucose-lowering drugs. It is a drug for the treatment of type 2 diabetes. It could stimulate insulin secretion by closing the ATP-sensitive K(+) K(ATP) channels in pancreatic beta-cells. It has a high affinity for SUR1 subunits. It was developed by Kissei and Takeda together. Now it has been listed. Uses: Mitiglinide is a drug for the treatment of type 2 diabetes. Synonyms: [2(S)-cis]-Octahydro-gamma-oxo-alpha-(phenylmethyl)-2H-isoindole-2-butanoic acid. Grades: > 95%. CAS No. 145375-43-5. Molecular formula: C19H25NO3. Mole weight: 315.41. | |
| Mitiglinide-acyl-b-D-glucuronide | Mitiglinide-acyl-b-D-glucuronide is a highly efficacious pharmaceutical compound extensively employed, aiding in the research of type 2 diabetes mellitus. This compound exerts an augmented stimulatory effect on insulin secretion. Molecular formula: C25H33NO9. Mole weight: 491.53. | |
| Mitiglinide Acyl- β-D-glucuronide | Mitiglinide Acyl- β-D-glucuronide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C25H33NO9, Molecular Weight: 491.53. US Biological Life Sciences. | Worldwide |
| Mitiglinide Acyl-β-D-glucuronide | Mitiglinide-acyl-β-D-glucuronide, is a metabolite of KAD-1229, which binds to sulfonylurea receptors and inhibits the activity of ATP-sensitive K+ channel in MIN 6 cells. It is used as an Antidiabetic agent. Grades: > 95%. Molecular formula: C25H33NO9. Mole weight: 491.53. | |
| Mitiglinide calcium | 100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C19H24NO3 ·0.5Ca. CAS No. 145525-41-3. Prepack ID 23856829-100mg. Molecular Weight 334.44. See USA prepack pricing. | |
| Mitiglinide calcium | Mitiglinide Calcium (KAD-1229 anhydrous), an insulinotropic agent, is an ATP-sensitive K + (K ATP ) channel antagonist. Mitiglinide Calcium is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell K ATP channel). Mitiglinide Calcium can be used for the research of type 2 diabetes [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KAD-1229 anhydrous; S21403 anhydrous. CAS No. 145525-41-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-17398. | |
| Mitiglinide calcium hydrate | Mitiglinide calcium hydrate, a derivative of benzylsuccinic acid, is a highly selective KATP channel antagonist. Uses: Hypoglycemic agents. Synonyms: calcium;(2S)-4-[(3aS,7aR)-1,3,3a,4,5,6,7,7a-octahydroisoindol-2-yl]-2-benzyl-4-oxobutanoate;dihydrate 207844-01-7 C38H48CaN2O6.2H2O Mitiglinidecalcium Calcium Mitiglinide 2150AH. Grades: >99.0%. CAS No. 207844-01-7. Molecular formula: C38H52CaN2O8. Mole weight: 704.91. | |
| Mitiglinide calcium hydrate | Mitiglinide calcium hydrate (KAD-1229), an insulinotropic agent, is an ATP-sensitive K + (K ATP ) channel antagonist. Mitiglinide calcium hydrate is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell K ATP channel). Mitiglinide Calcium hydrate can be used for the research of type 2 diabetes [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KAD-1229; S-21403. CAS No. 207844-01-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0682A. | |
| Mitiglinide (calcium salt, hydrate) | Mitiglinide (calcium salt, hydrate). Uses: For analytical and research use. Group: Impurity standards. CAS No. 207844-01-7. Molecular Formula: C38H52CaN2O8. Mole Weight: 704.92. Catalog: APB207844017. | |
| Mitiglinide Impurity 1 Calcium Salt | An impurity of Mitiglinide, which is a antidiabetic drug and a short term insulinotropic sulfonylurea receptor ligand. Synonyms: (R)-2-benzyl-4-((3aR,7aR)-hexahydro-1H-isoindol-2(3H)-yl)-4-oxobutanoic acid Calcium Salt. Grades: > 95%. Molecular formula: C19H24NO3. 0.5Ca. H2O. Mole weight: 352.69. | |
| Mitiglinide Impurity 2 | Mitiglinide Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1R,2S)-cyclohexane-1,2-dicarboxylic acid. CAS No. 610-09-3. Molecular Formula: C8H12O4. Mole Weight: 172.18. Catalog: APB610093. | |
| Mitiglinide Impurity B | Mitiglinide Impurity B is an impurity in commercial preparation of Mitiglinide. Synonyms: 2-benzylbutanedioic acid. Grades: > 95%. Molecular formula: C11H12O4. Mole weight: 208.21. | |
| Mitiglinide Impurity C | Mitiglinide Impurity C is an impurity in commercial preparation of Mitiglinide. Synonyms: 2-(cyclohexylmethyl)-4-(2,3-dihydro-1H-isoindol-2- yl)-4-oxobutanoic acid. Grades: > 95%. Molecular formula: C19H25NO3. Mole weight: 315.41. | |
| Mitiglinide Impurity D | An impurity of Mitiglinide, which is a antidiabetic drug and a short term insulinotropic sulfonylurea receptor ligand. Synonyms: Butanedioic acid, (phenylmethyl)-, (R)-; Succinic acid, benzyl-, D-(+)- (8CI); (2R)-2-(Phenylmethyl)butanedioic acid; (+)-α-Benzylsuccinic acid. Grades: > 95%. CAS No. 21307-97-1. Molecular formula: C11H12O4. Mole weight: 208.22. | |
| Mitiglinide impurity E | Mitiglinide Impurity E is an impurity of Mitiglinide, which is a antidiabetic drug and a short term insulinotropic sulfonylurea receptor ligand. Grades: > 95%. Molecular formula: C20H27NO4. Mole weight: 345.43. | |
| Mitiglinide Impurity I | Grades: > 95%. Molecular formula: C19H25NO3. Mole weight: 315.42. | |
| Mitindomide | Heterocyclic Organic Compound. Alternative Names: Benzenebismaleimide adduct; tricyclo<4.2.2.02,5>dec-9-ene-3,4,7,8-tetracarboxylic acid diimide; 3a,3b,4,4a,7a,8,8b-octahydro-4,8-ethenopyrrolo[3,4:3,4]cyclobut[1,2-f]isoindole-1,3,5,7[2H,6H]tetrone. CAS No. 10403-51-7. Molecular formula: C14H12N2O4. Mole weight: 272.26. Purity: 0.96. IUPACName: Mitindomide. Density: 1.518g/cm³. Catalog: ACM10403517. | |
| Mitiperstat | Mitiperstat (AZD4831) is an effective oral inhibitor of myeloperoxidase (MPO). Mitiperstat can reduce inflammation and improve microvascular function, and it can be used in studies related to heart failure, preserved or mildly reduced ejection fraction, non-alcoholic fatty liver disease, and chronic obstructive pulmonary disease [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD4831. CAS No. 1933460-19-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145581. | |
| Mitiromycin A2 | Mitiromycin A2 is a quinone antibiotic produced by Streptorverticilliim verticillatus AA-849, AB-286. It has weak anti-Gram-positive bacteria activity. Synonyms: Mitiromycin; 2-Hydroxy-6-methoxy-7, 11-dimethyl-4, 4a, 10, 10a, 11, 11a-hexahydroazireno[2', 3':3, 4]pyrrolo[1, 2-a][1, 3]oxazino[4, 5-b]indole-5, 8-dione. CAS No. 27164-43-8. Molecular formula: C16H17N3O5. Mole weight: 331.32. | |
| MitMAB | MitMAB. Group: Biochemicals. Grades: Purified. CAS No. 1119-97-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MitMAB | MitMAB, an organic building block and cationic surfactant, is a dynamin inhibitor that inhibits the GTPase activity of dynamin I (Ki = 940 nM; IC50=3.1 μM). It has been used in a study to assess a surfactant-controlled synthetic method to obtain a nanophase of mesoporous ceria-zirconia solid solution containing cationic defects in the crystalline structure. Uses: Quaternary ammonium compounds are used in disinfectants and sanitizers to treat swimming pools and industrial water reservoirs, as antiseptics for cleaning wounds, skin, and burns, in hair conditioners, as softeners for textiles and paper, and as pigment dispersers. Synonyms: Tetradecyltrimethylammonium bromide; (1-Tetradecyl)trimethylammonium Bromide Cetrimide BP; MTAB ; Microcide II; Morpan T; Myristyltrimethylammonium bromide; Myrtrimonium Bromide; Mytab; N,N,N-Trimethyl-1-tetradecanaminium Bromide;N-Tetradecyl-N,N,N-trimethylammonium Bromide; Pentonium 4Br40;Quaternium 13; Querton 14Br40; TTAB; TTAB (surfactant); Tetradecyltrimethylammonium Bromide; Tetradonium Bromide; Trimethylmyristylammonium Bromide; n-Tetradecyltrimethylammonium Bromide. Grades: >98.0%(T). CAS No. 1119-97-7. Molecular formula: C17H38BrN. Mole weight: 336.39. | |
| Mitob | Phosphonium-Based Ionic Liquids. Alternative Names: (3-Boronophenyl)methyl]triphenyl-phosphonium,monobromide. CAS No. 1247025-84-8. Molecular formula: C25H23BBrO2P. Mole weight: 477.14. Purity: 98%+. Catalog: ACM1247025848. | |
| MitoBloCK-6 (2- ( ( (4-Anilinophenyl) imino) methyl) -4, 6-dichlorophenol, 2, 4-Dichloro-6- ( ( ( ( (phenylamino) phenyl) imino) methyl) phenol) , Mitochondrial Protein Import Blocker from the Carla Koehler Laboratory, MB6, MB-6) | A cell-permeable, stable dichlorosalicylalde hyde Schiff's base that acts as a potent, selective inhibitor of Mia40/Erv1 redox-mediated import pathway (IC50 = 700nM, 900nM, and 1.4uM for ALR, Erv1, and Erv2, respectively). Significantly reduces the import of CX9 proteins, Erv1, Tim23, and ADP/ATP carrier (AAC). However, it does not affect mitochondrial membrane integrity as evidenced by the lack of aconitase, AAC, Tim54, Mia40, and cytochrome c release. Has no effect on protein disulfide isomerase, flavin adenine dinucleotide, and succinate dehydrogenase activities and does not disrupt mitochondrial net work or reduce viability of cells even at high concentrations (~100uM in HeLa and HEK293 cells). Reported to specifically cause cytochrome c release, activate caspase-3, and induce apoptosis in human embryonic stem cells (~20uM), but not in differentiated cells. Reversibly impairs cardiac development and reduces heart rate in zebra fish that is attributed to mitochondrial dysfunction. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. Molecular Formula: C??H??Cl?N?O, Primary Target: Erv1. US Biological Life Sciences. | Worldwide |
| Mitobronitol | 1,6-Dibromo-1,6-dideoxy-D-mannitol is a mannitol derivative with bromides substituted for the terminal hydroxyl groups. Synonyms: 1,6-Dibromo-1,6-dideoxy-D-mannitol; Myebrol; 1,6-Dibromomannitol; 1,6-Dibromomannitol; Dibromannitol; NSC-94100. Grades: >98%. CAS No. 488-41-5. Molecular formula: C6H12Br2O4. Mole weight: 307.97. | |
| Mitochondrial ATF Translocator, SBI-0087702 (N- ( (4-methoxynaphthalen-1-yl) methyl) -2- (4-methoxyphenyl) ethanamine, SBI0087702, SBI 0087702) | A cell permeable naphthalene derivative that promotes the translocation of ATF2 from nucleus to mitochondria via PKCe that results in mitochondrial membrane leakage and cell death in melanoma cells (WM793 and UACC903). Diminishes cell motility and anchorage-free growth in melanoma cells (<90% at 10uM) and reduces their migration in an ATF2-dependent manner. Shown to reduce ATF2 phosphorylation on Thr52, 69, and 71. However, it does not affect the activity of Erk1/2, Akt, pan-PKC. Cells expressing ATF2T52E do not exhibit any loss of mitochondrial membrane potential. Does not induce apoptosis in normal melanocytes even at high concentrations (~20 mM) and has no effect on the localization or translocation of p53, STAT3, or b-catenin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Mitochondrial Fusion Promoter, M1 ( (E) -4-Chloro-2- (1- (2- (2, 4, 6-trichlorophenyl) hydrazono) ethyl) phenol) | A cell-permeable phenylhydrazone that restores mitochondrial tubular network formation in MEF lacking either of the two outer mitochondrial membrane (OMM) mitofusins (EC50=5.3 and 4.42 mM, respectively, in Mfn1 or Mfn2 knockout MEF cells) or in MPP+-treated SH-SY5Y cells (5uM 24h), but not in MEF lacking both Mfn1/2 or the inner mitochondrial membrane (IMM) fusion mediator Opa1 (optic atrophy1). M1 (5uM 24h) is reported to boost the downregulated ATP5A & ATP5B protein level in Mfn1 or Mfn2 knockout MEF to the wild-type MEF level and ATPase inhibitor oligomycin at 5uM is shown to completely offset the mitochondrial fusion effect by 5uM M1 in Mfn1 knockout MEF. Comparing to mdivi-1, M1 exerts its effect via promoting fusion rather than inhibiting fission or division. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| mitochondrial intermediate peptidase | A homologue of thimet oligopeptidase. Natural substrates are precursor proteins that have already been processed by mitochondrial processing peptidase. In peptidase family M3 (thimet oligopeptidase family). Group: Enzymes. Synonyms: mitochondrial intermediate precursor-processing proteinase; MIP. Enzyme Commission Number: EC 3.4.24.59. CAS No. 136447-30-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4341; mitochondrial intermediate peptidase; EC 3.4.24.59; 136447-30-8; mitochondrial intermediate precursor-processing proteinase; MIP. Cat No: EXWM-4341. |  |
| mitochondrial processing peptidase | Known from the mitochondrial matrix of fungi and mammals. Formed from two subunits, both homologous with pitrilysin, and the products of the MAS1 and MAS2 genes in yeast. In peptidase family M16 (pitrilysin family). Group: Enzymes. Synonyms: processing enhancing peptidase (for one of two subunits); mitochondrial protein precursor-processing proteinase; matrix peptidase; matrix processing peptidase; matrix processing proteinase; mitochondrial protein precursor-processing proteinase; MPP. Enzyme Commission Number: EC 3.4.24.64. CAS No. 86280-61-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4347; mitochondrial processing peptidase; EC 3.4.24.64; 86280-61-7; processing enhancing peptidase (for one of two subunits); mitochondrial protein precursor-processing proteinase; matrix peptidase; matrix processing peptidase; matrix processing proteinase; mitochondrial protein precursor-processing proteinase; MPP. Cat No: EXWM-4347. | |
| mitochondrial protein-transporting ATPase | A non-phosphorylated, non-ABC (ATP-binding cassette) ATPase involved in the transport of proteins or preproteins into mitochondria using the TIM protein complex. (TIM is the protein transport machinery of the inner mitochondrial membrane that contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor.). Group: Enzymes. Enzyme Commission Number: EC 7.4.2.3 (Formerly EC 3.6.3.51). Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4690; mitochondrial protein-transporting ATPase; EC 3.6.3.51. Cat No: EXWM-4690. | |
| Mitochondrial Pyruvate Carrier Inhibitor, UK5099 ((E)-2-Cyano-3-(1-phenyl-1H-indol-3-yl)acrylic acid, (E)-2-Cyano-3-(1-phenyl-1H-indol-3-yl)-2-propenoic acid, MPC Inhibitor, PF-1005023) | A cell-permeable alpha-cyanocinnamate compound that acts as a rapid, active site thiol modifying, time-dependent and non-competitive inhibitor of bi-directional pyruvate transport across plasma membranes in yeast, bacteria, Drosophila, and humans (IC50 = 50nM in rat heart mitochondria; Ki ≤1uM) with excellent selectivity over monocarboxylates and anions. Shown to significantly decrease pyruvate-driven respiration, enhance glucose uptake and activate AMPK (2uM in human myocytes and skeletal muscle myotubes). Group: Biochemicals. Grades: Highly Purified. CAS No. 56396-35-1. Pack Sizes: 5mg, 25mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. | Worldwide |
| mitochondrial tRNA pseudouridine27/28 synthase | The mitochondrial enzyme Pus2p is specific for position 27 or 28 in mitochondrial tRNA. Group: Enzymes. Synonyms: Pus2; Pus2p; RNA:pseudouridine synthases 2. Enzyme Commission Number: EC 5.4.99.44. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5586; mitochondrial tRNA pseudouridine27/28 synthase; EC 5.4.99.44; Pus2; Pus2p; RNA:pseudouridine synthases 2. Cat No: EXWM-5586. | |
| Mitochondria-Targeted Compound Library | A unique collection of 447 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine; - Targets include mitochondria related targets, such as ATPase, mitochondria-associated hexokinase, Bcl-2, NADP, etc. and inhibitors for the autophagy initiating factor, ULK1, also include other promising mitochondria-targeted compounds such as lonidamine, paclitaxel, etc; - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L5300. Categories: Mitochondria-Targeted Compounds Libraries. |  |
| Mitochonic acid 5 | Mitochonic acid 5 binds mitochondria and ameliorates renal tubular and cardiac myocyte damage. Mitochonic acid 5 modulates mitochondrial ATP synthesis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MA-5. CAS No. 1354707-41-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111536. | |
| Mitochonic Acid 5 | Mitochonic Acid 5 is an effective mitochondrial ATP production enhancer. It binds to mitochondria and improves renal tubular and cardiomyocyte damage. Synonyms: Mitochonic Acid 5(MA-5); SCHEMBL15747705; MA-5; MA 5; MA5. Grades: 98%. CAS No. 1354707-41-7. Molecular formula: C18H13F2NO3. Mole weight: 329.3. | |
| Mitochonic Acid 5 | Mitochonic Acid 5 is a derivative of the plant hormone indole-3-acetic acid. It has been shown to improve survival of fibroblasts from patients with mitochondrial diseases. Group: Others. Alternative Names: Mitochonic Acid 5; MA-5; MA 5; MA5. CAS No. 1354707-41-7. Molecular formula: C18H13F2NO3. Mole weight: 329.3. Appearance: Solid powder. Purity: >98%. IUPACName: 4-(2,4-Difluorophenyl)-2-(1H-indol-3-yl)-4-oxobutanoic acid. Canonical SMILES: O=C (O)C (C1=CNC2=C1C=CC=C2)CC (C3=CC=C (F)C=C3F)=O. Catalog: ACM1354707417. | |
| MitoE10 | MitoE10, a mitochondria-targeted antioxidants comprising a lipophilic triphenylphosphonium cation attached to the antioxidant chroman moiety of vitamin E by an alkyl linker, was synthesised starting from 1-hydroxy-11-dodecyne, obtained by the addition of 1-bromononane to lithiated propargyl THP ether followed by triple bond migration using NaH and ethylenediamine. Preliminary biological data demonstrate that MitoE10 shows greater efficacy in preventing lipid peroxidation, mitochondrial oxidative damage and damage to mitochondrial DNA than non-targeted compounds. Synonyms: (10-(6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)decyl)triphenylphosphonium methanesulfonate; MitoE10; Mito E10; MitoE-10; Vitaman E-triphenylphosphonium conjugate; 1810703-64-0 (mesylate salt); 1810703-63-9 (cation). Grades: >98%. CAS No. 1810703-63-9. Molecular formula: C42H55O5PS. Mole weight: 702.93. | |
| mitogen-activated protein kinase | Phosphorylation of specific tyrosineand threonine residues in the activation loop of this enzyme by EC 2.7.12.2, mitogen-activated protein kinase kinase (MAPKK) is necessary for enzyme activation. Once activated, the enzyme phosphorylates target substrates on serine or threonine residues followed by a proline. A distinguishing feature of all MAPKs is the conserved sequence Thr-Xaa-Tyr (TXY). Mitogen-activated protein kinase (MAPK) signal transduction pathways are among the most widespread mechanisms of cellular regulation. Mammalian MAPK pathways can be recruited by a wide variety of stimuli including hormones (e.g. insulin and growth hormone), mitogens (e.g. epidermal growth...pk; PMK-1; PMK-2; PMK-3; pp42; pp44mapk; p44mpk; SAPK; STK26; stress-activated protein kinase. Enzyme Commission Number: EC 2.7.11.24. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3144; mitogen-activated protein kinase; EC 2.7.11.24; c-Jun N-terminal kinase; Dp38; ERK; ERK1; ERK2; extracellular signal-regulated kinase; JNK; JNK3α1; LeMPK3; MAP kinase; MAP-2 kinase; MAPK; MBP kinase I; MBP kinase II; microtubule-associated protein 2 kinase; microtubule-associated protein kinase; myelin basic protein kinase; p38Δ; p38-2; p42 mitogen-activated protein kinase; p42mapk; PMK-1; PMK- | |
| Mitogen activated protein kinase from rat, Recombinant | Mitogen-activated protein kinases (MAPK) are protein kinases that are specific to the amino acids serine, threonine, and tyrosine. MAPKs belong to the CMGC (CDK/MAPK/GSK3/CLK) kinase group. MAPKs are involved in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. They regulate cell functions including proliferation, gene expression, differentiation, mitosis, cell survival, and apoptosis. > 95% (sds-page), buffered aqueous glycerol solution, recombinant, expressed in e. coli (n-terminal histidine tagged). Group: Enzymes. Synonyms: ERK2; Extracellular-signal regulated kinase; MAP Kinase Activated from rat; MAPK; Mitogen activated protein kinase. Purity: > 95% (SDS-PAGE). MAP kinase. Mole weight: mol wt 42 kDa. Activity: > 500 U/mg. Stability: -70°C. Form: buffered aqueous glycerol solution. Source: E. coli. Species: Rat. ERK2; Extracellular-signal regulated kinase; MAP Kinase Activated from rat; MAPK; Mitogen activated protein kinase. Pack: vial of 100 ng. Cat No: NATE-0443. | |
| mitogen-activated protein kinase kinase | This enzyme is a dual-specific protein kinase and requires mitogen-activated protein kinase kinase kinase (MAPKKK) for activation. It is required for activation of EC 2.7.11.24, mitogen-activated protein kinase. Phosphorylation of MEK1 by Raf involves phosphorylation of two serine residues. Mitogen-activated protein kinase (MAPK) signal transduction pathways are among the most widespread mechanisms of cellular regulation. Mammalian MAPK pathways can be recruited by a wide variety of stimuli including hormones (e.g. insulin and growth hormone), mitogens (e.g. epidermal growth factor and platelet-derived growth factor), vasoactive peptides (e.g. angiotensin-II and endothelin), inflammatory cytokines of the tumour necrosis factor (TNF) family and environmental stresses such as osmotic shock, ionizing radiation and ischaemic injury. Group: Enzymes. Synonyms: MAP kinase kinase; MAP kinase kinase 4; MAP kinase kinase 7; MAP kinase or ERK . Enzyme Commission Number: EC 2.7.12.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3162; mitogen-activated protein kinase kinase; EC 2.7.12.2; MAP kinase kinase; MAP kinase kinase 4; MAP kinase kinase 7; MAP kinase or ERK kinase; MAP2K; MAPKK; MAPKK1; MEK; MEK1; MEK2; MKK; MKK2; MKK4; MKK6; MKK7; STK27. Cat No: EXWM-3162. | |
| mitogen-activated protein kinase kinase kinase | This enzyme phosphorylates and activates its downstream protein kinase, EC 2.7.12.2, mitogen-activated protein kinase kinase (MAPKK) but requires MAPKKKK for activation. Some members of this family can be activated by p21-activated kinases (PAK/STE20) or Ras. While c-Raf and c-Mos activate the classical MAPK/ERK pathway, MEKK1 and MEKK2 preferentially activate the c-Jun N-terminal protein kinase(JNK)/stress-activated protein kinase (SAPK) pathway. Mitogen-activated protein kinase (MAPK) signal transduction pathways are among the most widespread mechanisms of cellular regulation. Mammalian MAPK pathways can be recruited by a wide variety of stimuli including hormones (e...mes. Synonyms: cMos; cRaf; MAPKKK; MAP3K; MAP kinase kinase kinase; MEKK; MEKK1; MEKK2; MEKK3; MEK kinase; Mil/Raf; MLK-like mitogen-activated protein triple kinase; MLTK; MLTKa; MLTKb; REKS; STK28. Enzyme Commission Number: EC 2.7.11.25. CAS No. 146702-84-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3145; mitogen-activated protein kinase kinase kinase; EC 2.7.11.25; 146702-84-3; cMos; cRaf; MAPKKK; MAP3K; MAP kinase kinase kinase; MEKK; MEKK1; MEKK2; MEKK3; MEK kinase; Mil/Raf; MLK-like mitogen-activated protein triple kinase; MLTK; MLTKa; MLTKb; REKS; STK28. Cat No: EXWM-3145. | |
| Mitogenic Pentapeptide | Mitogenic Pentapeptide represents a potent activator for monocytes/macrophages and B lymphocytes. Synonyms: Tripalmitoyl pentapeptide; Bppp-cssaa; P3C-Ssna; Pam3Cys-ser-ser-asn-ala; 2,3-Bis(palmitoyloxy)propyl-N-palmitoylpentapeptide. CAS No. 87173-03-3. Molecular formula: C67H124N6O14S. Mole weight: 1269.80. | |
| Mitoguazone | Mitoguazone is a guanylhydrazone with potential antineoplastic activity. Mitoguazone competitively inhibits S-adenosyl-L-methionine decarboxylase (SAMD), an enzyme involved in the synthesis of polyamines, resulting in decreased proliferation of tumor cells, antimitochondrial effects, and p53-independent apoptosis. Polyamines, specifically spermine and spermidine, are essential for thymidine kinase production, DNA synthesis, and cell proliferation. Synonyms: MeGAG; methyl-G; methyl-GAG; MGBG; MGGH; DRG-0223; DRG 0223; DRG0223; NSC32946; NSC 32946; NSC-32946. Grades: 99.38%. CAS No. 459-86-9. Molecular formula: C5H12N8. Mole weight: 184.21. | |
| Mitoguazone | Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) is a synthetic polycarbonyl derivative with potent antineoplastic activity. Mitoguazone is a brain-penetrant and competitive S-adenosyl-methionine decarboxylase (SAMDC) inhibitor that disrupts polyamine biosynthesis. Mitoguazone induces cell apoptosis. Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages. Mitoguazone has the potential for acute leukemia, Hodgkin's and non-Hodgkin's lymphoma treatment [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Methylglyoxal-bis(guanylhydrazone); MGBG; Methyl-GAG. CAS No. 459-86-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-106634. | |
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