A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
MitoTEMPOL is a a mitochondria-targeted nitroxide that reduces mitochondrial O2 - to H2O2 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1101113-39-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-115386.
MitoTracker Deep Red FM
MitoTracker Deep Red (MTDR) FM fluorescent dye that selectively accumulates in the mitochondrial matrix. MitoTracker Deep Red FM covalently binds mitochondrial proteins by reacting with free mercaptan of cysteine residues, allowing staining of mitochondrial membrane potential independent of membrane potential. Excitation/emission wavelength 644/665 nm[1]. MitoTracker Deep Red dyes have an excitation/emission wavelength of 633/650-750 nm[2].The Ex/Em of MitoTracker Deep Red (MTDR) FM is 644/665 nm. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: MTDR FM. CAS No. 873315-86-7. Pack Sizes: 50 ?g; 100 ?g. Product ID: HY-D1783.
MitoTracker Green FM
Mito-Tracker Green is a green fluorescent dye that selectively accumulates in the mitochondrial matrix. MitoTracker Green FM covalently binds mitochondrial proteins by reacting with free mercaptan of cysteine residues, allowing staining of mitochondrial membrane potential independent of membrane potential. Excitation/emission wavelength 490/523 nm. Uses: Scientific research. Group: Fluorescent dye. CAS No. 201860-17-5. Pack Sizes: 50 ?g. Product ID: HY-135056.
Mitoxantrone
Mitoxantrone is a potent topoisomerase II inhibitor. Mitoxantrone also inhibits protein kinase C ( PKC ) activity with an IC 50 of 8.5 μM. Mitoxantrone induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone shows antitumor activity [1] [2] [3] [4]. Mitoxantrone also has anti- orthopoxvirus activity with EC 50 s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Mitozantrone; NSC 301739. CAS No. 65271-80-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-13502.
Mitoxantrone
Mitoxantrone is a DNA intercalating drug. Mitoxantrone inhibits DNA synthesis. Mitoxantrone is used as an anti-cancer agent. Group: Biochemicals. Alternative Names: 1, 4-Dihydroxy-5, 8-bis[[2-[ (2-hydroxyethyl) amino]ethyl]amino]-9, 10-anthracenedione; 1, 4-Bis [ (2- (2- hydroxyethylamino) ethyl) amino] -5, 8-di hydroxyanthraquinone. Grades: Highly Purified. CAS No. 65271-80-9. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Mitoxantrone
Mitoxantrone is a type II topoisomerase inhibitor with IC50 of 2.0 μM, 0.42 mM for HepG2 and MCF-7/wt cells, respectively. It is used in the treatment of certain types of cancer, mostly metastatic breast cancer, acute myeloid leukemia, and non-Hodgkin's lymphoma. Uses: Analgesics. Synonyms: mitoxantrone; 65271-80-9; Mitoxanthrone; Mitozantrone; DHAQ. Grades: >98%. CAS No. 65271-80-9. Molecular formula: C22H28N4O6. Mole weight: 444.48.
Mitoxantrone
50mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C22H28N4O6. CAS No. 65271-80-9. Prepack ID 28035650-50mg. Molecular Weight 444.48. See USA prepack pricing.
An anti-tumor antibiotic and type II topoisomerase inhibitor. It disrupts DNA synthesis and DNA repair in both healthy and cancer cells. Mitoxantrone also displays broad immunosuppressive activity inhibiting proliferation of all classes of lymphocytes and inducing apoptosis of antigen-presenting T cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 65271-80-9. Pack Sizes: 50mg, 250mg. US Biological Life Sciences.
A DNA intercalating drug. Inhibits DNA synthesis. Used as an anti-cancer agent. Group: Biochemicals. Alternative Names: 1, 4-Dihydroxy-5, 8-bis[[2-[ (2-hydroxyethyl) amino]ethyl]amino]-9, 10-anthracenedione-d8. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Mitoxantrone dihydrochloride
It is a type II topoisomerase inhibitor with IC50 of 2.0 μM, 0.42 mM for HepG2 and MCF-7/wt cells, respectively. Mitoxantrone dihydrochloride is an antiviral, antibacterial, antiprotozoal, immunomodulating and antineoplastic anthraquinone derivative. Synonyms: 1, 4-dihydroxy-5, 8-bis ( (2- ( (2-hydroxyethyl) amino) ethyl) amino) anthracene-9, 10-dione dihydrochloride; DHAQ; CL-232325; CL 232325; CL232325; Novantrone; Mitroxone; Neotalem; Onkotrone; Pralifan; Mitoxantrone 2HCl; Immunex. Grades: >98%. CAS No. 70476-82-3. Molecular formula: C22H28N4O6.2HCl. Mole weight: 517.40.
Mitoxantrone dihydrochloride
Mitoxantrone dihydrochloride is a potent topoisomerase II inhibitor. Mitoxantrone dihydrochloride also inhibits protein kinase C ( PKC ) activity with an IC 50 of 8.5 μM. Mitoxantrone dihydrochloride induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone dihydrochloride shows antitumor activity [1] [2] [3] [4]. Mitoxantrone dihydrochloride also has anti- orthopoxvirus activity with EC 50 s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Mitozantrone dihydrochloride; NSC 301739 dihydrochloride. CAS No. 70476-82-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-13502A.
Mitoxantrone dihydrochloride
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C22H28N4O6 · 2HCl. CAS No. 70476-82-3. Prepack ID 24343907-1g. Molecular Weight 517.4. See USA prepack pricing.
Mitoxantrone is a DNA intercalating drug. Mitoxantrone inhibits DNA synthesis. Mitoxantrone is used as an anti-cancer agent. Group: Biochemicals. Alternative Names: 1, 4-Dihydroxy-5, 8-bis[[2-[ (2-hydroxyethyl) amino]ethyl]amino]-9, 10-anthracenedione Hydrochloride; Bisantrone; CL 232315; DHAD; Immunex; Mitoxantrone Hydrochloride; NCI 301739; NSC 301739; Novantron; Novantrone; Novatrone. Grades: Highly Purified. CAS No. 70476-82-3. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Mitoxantrone hydrochloride
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardsapi standardseuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthracene-9,10-dione dihydrochloride,Mitoxantrone hydrochloride.
Mitoxantrone Impurity4
Mitoxantrone Impurity4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 100204-25-9. Molecular formula: C24H28ClF3N4O7. Mole weight: 576.95. Catalog: APB100204259.
Mitoxantrone Impurity A
An impurity of Mitoxantrone, which is a DNA intercalating drug. Synonyms: Des[2-[(2-Hydroxyethyl)amino]ethyl] Mitoxantrone; 1-Amino-5,8-dihydroxy-4-[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione. Grades: > 95%. CAS No. 89991-52-6. Molecular formula: C18H19N3O5. Mole weight: 357.37.
Mitoxantrone Impurity B
An impurity of Mitoxantrone, which is a DNA intercalating drug. Synonyms: 1-Deshydroxy Mitoxantrone; 4-Hydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione; 1-Deshydroxy DHAQ; Dihydroxyanthraquinone 1-Deshydroxy; Mitox 1-Deshydroxy; Mitoxanthrone 1-Deshydroxy; Mitozantrone 1-Deshydroxy; Nimitoxantron 1-Deshydroxy. Grades: > 95%. CAS No. 80189-44-2. Molecular formula: C22H28N4O5. Mole weight: 428.49.
Mitoxantrone Impurity C
An impurity of Mitoxantrone, which is a DNA intercalating drug. Synonyms: 2-Choloride-1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione; 2-Choloride-1,4-Bis[(2-(2-hydroxyethylamino)ethyl)amino]-5,8-dihydroxyanthraquinone. Grades: > 95%. Molecular formula: C22H27ClN4O6. Mole weight: 478.94.
Mitoxantrone Impurity D
An impurity of Mitoxantrone, which is a DNA intercalating drug. Synonyms: Mitoxantrone (2-Hydroxyethyl)piperazine Impurity; 1, 2, 3, 4-Tetrahydro-8, 11-dihydroxy-4- (2-hydroxyethyl) -6-[[2-[ (2-hydroxyethyl) amino]ethyl]amino]naphtho[2, 3-f]quinoxaline-7, 12-dione. Grades: > 95%. CAS No. 137132-70-8. Molecular formula: C22H26N4O6. Mole weight: 442.48.
Mitoxantrone Liposome
Mitoxantrone is an anthracycline that enters the nucleus of the cell and binds to DNA, thereby inhibiting nucleic acid synthesis and mitosis, leading to cell death. This product is a pre-formulated liposome with mitoxantrone. It is only for research purposes and for the injection to laboratory animals. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes.
Mitoxantrone System Suitability Mixture
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Mitragynine
Mitragynine is an indole alkaloid from the plant M. speciosa. It has stimulatory, antinociceptive, and opiate-like effects, acting through noradrenergic, serotonergic, and opioid receptors.1,2 Mitragynine has a higher affinity for the μ-opioid receptor than the δ- or κ-opioid receptors (pKi = 8.14, 7.22, and 5.96, respectively).2 Mitragynine and its derivatives have been identified in products sold as incense.3 The identification and quantification of mitragynine and related alkaloids, as well as their phase I and II metabolites, have been described.4-6 This product is intended for forensic applications.This product is qualified as a Reference Material that has been manufactured and tested to ISO/IEC 17025 and ISO 17034 international standards. Group: Biochemicals. Alternative Names: (αE,2S,3S,12bS)-3-Ethyl-1,2,3,4,6,7,12,12b-octahydro-8-methoxy-α-(methoxymethylene)-indolo[2,3-a]quinolizine-2-acetic Acid Methyl Ester; (-)-Mitragynine; 9-Methoxy-corynantheidine; 16,17-Didehydro-9,17-dimethoxy-corynan-16-carboxylic Acid Methyl Ester. Grades: Highly Purified. CAS No. 4098-40-2. Pack Sizes: 1mg, 5mg. Molecular Formula: C??H??N?O?, Molecular Weight: 398.5. US Biological Life Sciences.
Worldwide
Mitragynine-D3 solution
100 ?g/mL in methanol, ampule of 1 mL, certified reference material. Group: Hallucinogens standards.
Mitraphylline
Mitraphylline is the major pentacyclic oxindolic alkaloid presented in Uncaria tomentosa. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils [1]. Uses: Scientific research. Group: Natural products. CAS No. 509-80-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N6946.
MIV-150
MIV-150 is an allosteric inhibitor of HIV-1 and HIV-2 reverse transcriptase with both EC50 values of 1 nM in vitro. Synonyms: PC-815; 1-(5-cyanopyridin-2-yl)-3-[(1S,2S)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea. Grades: ≥98%. CAS No. 231957-54-3. Molecular formula: C19H17FN4O3. Mole weight: 368.4.
Mivacurium
Mivacurium is a bisbenzylisoquinolinium based and a short-duration non-depolarizing neuromuscular-blocking drug or skeletal muscle relaxant. It binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, which results in a block of neuromuscular transmission. It is used in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during mechanical ventilation or surgery. Uses: Mivacurium is a short-duration non-depolarizing neuromuscular-blocking drug or skeletal muscle relaxant. Synonyms: 2, 2'-[ (1, 8-Dioxo-4-octene-1, 8-diyl) bis (oxy-3, 1-propanediyl) ]bis[1, 2, 3, 4-tetrahydro-6, 7-dimethoxy-2-methyl-1-[ (3, 4, 5-trimethoxyphenyl) methyl]isoquinolinium; Isoquinolinium, 2,2'-((1,8-dioxo-4-octene-1,8-diyl)bis(oxy-3,1-propanediyl))bis(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-((3,4,5-trimethoxyphenyl)methyl)-;Bis[3-[(1R)-6,7-dimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propyl] (E)-oct-4-enedioate;BW-B-1090U;Mivacron;(1R,1'R)-2,2'-((((E)-oct-4-enedioyl)bis(oxy))bis(propane-3,1-diyl))bis(6,7-dimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinolin-2-ium). Grades: 95%. CAS No. 106791-40-6. Molecular formula: C58H80N2O14. Mole weight: 1029.28.
Mivacurium
Mivacurium. Uses: For analytical and research use. Group: Impurity standards. CAS No. 133814-19-4. Molecular formula: C58H80N2O142+. Mole weight: 1029.28. Catalog: APB133814194.
Mivacurium chloride
Mivacurium is a nicotinic acetylcholine receptors (nAChRs) antagonist and a non-depolarizing neuromuscular-blocking drug metabolized by plasma cholinesterase. Grades: ≥95%. CAS No. 106861-44-3. Molecular formula: C58H80Cl2N2O14. Mole weight: 1100.2.
Mivacurium Chloride
Mivacurium Chloride. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106861-44-3. Molecular formula: C58H80Cl2N2O14. Mole weight: 1100.18. Catalog: APB106861443.
Mivacurium Chloride Impurity 11
Mivacurium Chloride Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 104758-51-2. Molecular formula: C58H80Cl2N2O14. Mole weight: 1100.18. Catalog: APB104758512.
Mivacurium Chloride Impurity 12
Mivacurium Chloride Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 107740-63-6. Molecular formula: C58H80Cl2N2O14. Mole weight: 1100.18. Catalog: APB107740636.
Mivacurium Chloride Impurity 13
Mivacurium Chloride Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1R,1'R,2R,2'R)-2,2'-((((E)-oct-4-enedioyl)bis(oxy))bis(propane-3,1-diyl))bis(6,7-dimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinolin-2-ium) chloride. CAS No. 107740-65-8. Molecular formula: C58H80N2O14·2Cl. Mole weight: 1098.5. Catalog: APB107740658.
Mivacurium Chloride Impurity 21
Mivacurium Chloride Impurity 21. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1026602-92-5. Molecular formula: C6H13ClO2. Mole weight: 152.62. Catalog: APB1026602925.
Mivacurium Chloride Impurity 23
Mivacurium Chloride Impurity 23. Uses: For analytical and research use. Group: Impurity standards. CAS No. 104758-47-6. Molecular formula: C22H29NO5. Mole weight: 387.48. Catalog: APB104758476.
Mivacurium Chloride Impurity A
Mivacurium Chloride Impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1R,2S)-2-(3-hydroxypropyl)-6,7-dimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinolin-2-ium chloride. CAS No. 107740-66-9. Molecular formula: C25H36NO6·Cl. Mole weight: 482.01. Catalog: APB107740669.
Mivacurium Chloride Impurity B
Mivacurium Chloride Impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1R,2R)-2-(3-hydroxypropyl)-6,7-dimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinolin-2-ium chloride. CAS No. 107740-64-7. Molecular formula: C25H36NO6·Cl. Mole weight: 482.01. Catalog: APB107740647.
Mivacurium dichloride is a benzylisoquinoline derivative and is a short-acting non-depolarizing neuromuscular blocking agent and skeletal muscle relaxant. Mivacurium dichloride couples with the nAChR to reduce or inhibit the depolarizing effect of acetylcholine on the terminal disc of the muscle cell [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 106861-44-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1700A.
Mivebresib
Mivebresib is a BET inhibitor with potential antineoplastic activity. It disrupts critical transcription programs that drive prostate cancer growth to induce potent anti-tumor activity in vitro and in vivo. Mivebresib is also a MYC and the TMPRSS2-ETS fusion proteins inhibitor. Mivebresib can inhibit cell growth in susceptible tumors. Uses: Anti-tumor. Synonyms: ABBV-075; ABBV 075; ABBV075; Mivebresib;N-(4-(2,4-difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide. Grades: 98%. CAS No. 1445993-26-9. Molecular formula: C22H19F2N3O4S. Mole weight: 459.47.
Mivebresib
Mivebresib (ABBV-075) is a potent and orally active bromodomain and extraterminal domain (BET) bromodomain inhibitor. Mivebresib binds to BRD4 with a K i of 1.5 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABBV-075. CAS No. 1445993-26-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100015.
Mivobulin isethionate
Mivobulin isethionate is the isethionate salt of mivobulin, a synthetic colchicine analogue with potential antineoplastic activity. Mivobulin isethionate binds to tubulin, thereby inhibiting microtubule polymerization and mitosis. Uses: Antineoplastic agents. Synonyms: CI-980; CI 980; CI980. CAS No. 126268-81-3. Molecular formula: C19H25N5O6S. Mole weight: 451.50.
Mivorilaner
Mivorilaner is an antineoplastic and antiparasitic primarily used in veterinary medicine. Synonyms: Itabh-19-01; LY 3116151; LY3116151; LY-3116151. Grades: >98%. CAS No. 1414642-93-5. Molecular formula: C22H17Cl2F6N3O3S. Mole weight: 588.3.
Mix Coal Tar/Petroleum Extract in Methylene Chloride
Mix Coal Tar/Petroleum Extract in Methylene Chloride. Uses: For analytical and research use. Group: Process materials, geological, cement & soils. Catalog: APS009969. Shipping: Room Temperature.
Mixoxantrone HCI. Group: Biochemicals. Grades: Highly Purified. CAS No. 70476-82-3. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C22H28N4O6HCI. US Biological Life Sciences.
Worldwide
Mixture of 1,2,3-Propanetriol 2-(Dihydrogen phosphate) Sodium Salt Hydrate and 1,2,3-Propanetriol 1-(Dihydrogen phosphate) Sodium Salt Hydrate
1,2,3-Propanetriol 2-(Dihydrogen phosphate) is a serine-threonine phosphatase inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g, 10g. Molecular Formula: C3H7Na2O6P xH2O. US Biological Life Sciences.
Worldwide
Mixture of Ezetimibe (3R,4R,3'R)-Isomer and Ezetimibe (3R,4R,3'S)-Isomer
A stereoisomer of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L9) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: Mixture of Ezetimibe (3R,4R,3'R)-Isomer and Ezetimibe (3R,4R,3'S)-Isomer. Grades: > 95%. Molecular formula: C24H21F2NO3. Mole weight: 409.44.
Mixture of Ezetimibe (3S,4S,3'S)-Isomer and Ezetimibe (3S,4S,3'R)-Isomer
An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L34) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: Mixture of Ezetimibe (3S,4S,3'S)-Isomer and Ezetimibe (3S,4S,3'R)-Isomer. Grades: > 95%. Molecular formula: C24H21F2NO3. Mole weight: 409.44.
Mixture of (R)-Apomorphine-11-sulfate Potassium Salt-d5 + (R)-Apomorphine-10-sulfate. (d4-Major) (90%)
(R)-Apomorphine-11-sulfate Potassium Salt-d5 is the isotope labelled analog of (R)-Apomorphine-11-sulfate Potassium Salt (A727520); a derivative of (R)-Apomorphine (A727500) which is a dopamine (D1 and D2) receptor agonist, emetic, and antiparkinsonian. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C17H11D5KNO5S. US Biological Life Sciences.
Worldwide
Mixture of (Z)-3-chloro-Oxybutynin and (Z)-2-chloro-Oxybutynin
Mixture of (Z)-3-chloro-Oxybutynin and (Z)-2-chloro-Oxybutynin(Oxybutynin HCI Adduct Impurity) is an impurity of oxybutynin, which is an inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells. Synonyms: Oxybutynin HCI Adduct Impurity; (Z)-2-chloro-4-(diethylamino)but-2-en-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate compound with (Z)-3-chloro-4-(diethylamino)but-2-en-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate (1:1). Molecular formula: C44H64Cl2N2O6. Mole weight: 787.89.
Miyakamide A1
Miyakamide A1 is an antibiotic produced by Aspergillus flavus var. columnaris FKI-0739. It has insecticidal effect. Miyakamide A1 inhibits the growth of Artemia salina at a minimum concentration of 5 μg/mL. Miyakamide A1 has weak antixanthomonas activity. It inhibits P388 cells with an IC50 of 10.5 μg/mL. CAS No. 497252-38-7. Molecular formula: C31H32N4O3. Mole weight: 508.61.
Miyakamide A2
Miyakamide A2 is an antibiotic produced by Aspergillus flavus var. columnaris FKI-0739. It has insecticidal effect. Miyakamide A2 inhibits the growth of Artemia salina at a minimum concentration of 5 μg/mL. Miyakamide A1 has weak antixanthomonas activity. It inhibits P388 cells with an IC50 of 12.2 μg/mL. CAS No. 497252-39-8. Molecular formula: C31H32N4O3. Mole weight: 508.61.
Miyakamide B1
Miyakamide B1 is an antibiotic produced by Aspergillus flavus var. columnaris FKI-0739. It has insecticidal effect. Miyakamide B1 inhibits the growth of Artemia salina at a minimum concentration of 20 μg/mL. It inhibits P388 cells with an IC50 of 8.8 μg/mL. CAS No. 497182-82-8. Molecular formula: C31H32N4O4. Mole weight: 524.61.
Miyakamide B2
Miyakamide B2 is an antibiotic produced by Aspergillus flavus var. columnaris FKI-0739. It has insecticidal effect. Miyakamide B2 inhibits the growth of Artemia salina at a minimum concentration of 20 μg/mL. It inhibits P388 cells with an IC50 of 7.6 μg/mL. CAS No. 497182-83-9. Molecular formula: C31H32N4O4. Mole weight: 524.61.
Mizacorat
Mizacorat (AZD9567; compound 15) is a potent, oral active, non-steroidal and selective glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8 nM. Exhibits excellent efficacy in the streptococcal cell wall (SCW) reactivation model of joint inflammation[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD9567. CAS No. 1893415-00-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-120012.
Mizagliflozin
Mizagliflozin (DSP-3235 free base) is a potent, orally active and selective SGLT1 inhibitor, with a K i of 27 nM for human SGLT1. Mizagliflozin displays 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic agent that can modify postprandial blood glucose excursion. Mizagliflozin also exhibits potential in the amelioration of chronic constipation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DSP-3235 free base; KGA-3235 free base; GSK-1614235 free base. CAS No. 666843-10-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17638.
Mizagliflozin
Mizagliflozin is a sodium-glucose transporter inhibitor. It is expected to improve postprandial hyperglycemia by suppressing glucose absorption from the intestine. It blocks intestinal glucose absorption and reduces GIP secretion in rats and humans, which suggests SGLT1 glucose transport is critical for GIP release. It is used for the treatment of diabetes. Synonyms: DSP-3235, DSP3235; DSP 3235; KGA-3235; KGA 3235; KGA3235; GSK-1614235; GSK 1614235; GSK1614235. Grades: 98%. CAS No. 666843-10-3. Molecular formula: C28H44N4O8. Mole weight: 564.68.
Mizolastine
Mizolastine is an orally active, high affinity and specific peripheral histamine H1 receptor antagonist (second generation antihistamine). Mizolastine effectively inhibits mRNA expression of VEGF165 , VEGF120 , TNF-α and KC. Mizolastine can be used in studies of allergic rhinitis and chronic idiopathic urticarial [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 108612-45-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B0164.
Mizolastine
A highly selective histamine H1-receptor antagonist (with no anticholinergic, antiadrenergic, or antiserotonin activity) for use in the treatment of allergic disorders, especially rhinitis and urticaria. Group: Biochemicals. Alternative Names: 2- [ [1- [1- [ (4-Fluorophenyl) methyl] -1H-benzimidazol-2-yl] -4-piperidinyl] methylamino] - 4(1H)-pyrimidinone; MKC 431; Mistamine; Mizollen; SL 850324; Zolistan. Grades: Highly Purified. CAS No. 108612-45-9. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Mizolastine dihydrochloride
The dihydrochloride salt form of Mizolastine which is effective in the treatment of seasonal allergic rhinitis, perennial allergic rhinitis and other allergy symptoms for playing the role as a histamine H1-receptor antagonis. IC50: 47nM. Uses: The dihydrochloride salt form of mizolastine which is effective in the treatment of seasonal allergic rhinitis, perennial allergic rhinitis and other allergy symptoms for playing the role as a histamine h1-receptor antagonis. Synonyms: Mizolastine (dihydrochloride); CS-1998. Grades: 98%. CAS No. 1056596-82-7. Molecular formula: C24H27Cl2FN6O. Mole weight: 505.42.
Mizoribine (NSC 289637), an imidazole nucleoside, inhibits HCV RNA replication with IC 50 of approximately 100 μM for anti-HCV activity. Immunosuppressant [1]. Mizoribine, an IMPDH inhibitor, inhibits replication of SARS-CoV with IC 50 s of 3.5 μg/mL and 16 μg/mL for SARS-CoV Frankfurt-1 and SARS-CoV HKU39849, respectively [2]. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 289637; HE 69. CAS No. 50924-49-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17470.
Mizoribine
Bredinin is a nucleoside antibiotic produced by Eupenicillum brefeldianum M-2166. It has anti-L-5178Y cell and anti-pox virus activity, not against bacteria and fungi. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: N'-(b-D-Ribofuranosyl)-5-hydroxyimidazole-4-carboxamide; Bredinin; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-hydroxy-1H-imidazole-4-carboxamide; 5-Hydroxy-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide. Grades: ≥95%. CAS No. 50924-49-7. Molecular formula: C9H13N3O6. Mole weight: 259.22.
Mizoribine
Mizoribine. Group: Biochemicals. Alternative Names: 1-(b-D-Ribofuranosyl)-5-hydroxyimidazole-4-carboxamide. Grades: Highly Purified. CAS No. 50924-49-7. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C9H13N3O6. US Biological Life Sciences.