A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
New methylene blue n. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3,7-BIS(ETHYLAMINO)2,8-DIMETHYLPHENAZATHIONIUM CHLORIDE, ZINC CHLORIDE SALT;BASIC BLUE 24;BASIC BLUE 24 ZINC CHLORIDE DOUBLE SALT;CI NO 52030;CI 52030;METHYLENE BLUE N;NEW METHYLENE BLUE;NEW METHYLENE BLUE N ZINC CHLORIDE DOUBLE SALT. Product Category: Heterocyclic Organic Compound. CAS No. 6586-5-6. Molecular formula: C36H44Cl4N6S2Zn. Mole weight: 832.11. Purity: CI 52030. Product ID: ACM6586056. Alfa Chemistry ISO 9001:2015 Certified.
New Methylene Blue N
New Methylene Blue N. Group: Biochemicals. Alternative Names: Basic Blue 24; CI 523. Grades: Highly Purified. CAS No. 6586-5-6. Pack Sizes: 10g, 25g. US Biological Life Sciences.
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New Methylene Blue N ≥90% (Dye content)
New Methylene Blue N ≥90% (Dye content). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g. US Biological Life Sciences.
Worldwide
New Methylene Blue N (ZnCl double salt)
5g Pack Size. Group: Analytical Reagents, Biochemicals, Stains & Indicators. Formula: C18H22ClN3S · 0.5ZnCl2. CAS No. 6586-5-6. Prepack ID 29731030-5g. Molecular Weight 416.05. See USA prepack pricing.
Nexinhib20 is an inhibitor that targets the interactions of Rab27a-JFC1 (IC50: 2.6 ?M) and Rac-1-GTP. Nexinhib20 can inhibit neutrophil exocytosis, adhesion, and ?2 integrin activation, and has anti-inflammatory activity. Nexinhib20 can be used in the research of diseases such as systemic inflammation and myocardial ischemia-reperfusion injury[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 331949-35-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125792.
Nexturastat A
Nexturastat A is a potent, selective HDAC6 inhibitor. Nexturastat A has inhibitory for HDAC6 with an IC50 of 5 nM. Nexturastat A can be used for the research of multiple myeloma (MM)[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1403783-31-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16699.
Nexturastat A (4-((1-butyl-3-phenylureido)methyl)-N-hydroxybenzamide)
Nexturastat A is an aryl urea derivative that acts as a potent and highly selective inhibitor of histone deacetylase 6 (HDAC6) (IC50 = 5.02 ± 0.60nm). Displays 600-, 1380-, 1330-, 1870-, -2330, -888, -190, -1340, -1510, and -1020-fold selectivities over HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, HDAC7, HDAC8, HDAC9, HDAC10, and HDAC11, respectively. Nexturastat A also displays antiproliferative effects against melanoma cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ne-Z-D-lysine
Ne-Z-D-lysine. Group: Biochemicals. Alternative Names: Nε-Z-D-lysine. Grades: Highly Purified. CAS No. 34404-32-5. Pack Sizes: 2g, 5g, 10g, 25g. US Biological Life Sciences.
Worldwide
Ne-Z-D-lysine 98+% (HPLC)
Ne-Z-D-lysine 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Ne-Z-D-lysine benzyl ester hydrochloride
Ne-Z-D-lysine benzyl ester hydrochloride. Group: Biochemicals. Alternative Names: D-Lys(Z)-OBzl·HCl. Grades: Highly Purified. CAS No. 156917-23-6. Pack Sizes: 1g, 2g. US Biological Life Sciences.
NF110 is a P2X 3 receptor antagonist ( K i=36 nM) and inactive toward P2Y receptors stably expressed (IC 50 s > 10 M). NF110 blocks alphabeta-methylene-ATP-induced currents (IC 50 = 527 nM) in rat dorsal root ganglia neurons [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 111150-22-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108671.
NF 110
NF 110. Group: Biochemicals. Grades: Purified. CAS No. 111150-22-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Nf 157
Nf 157. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NF 157. Product Category: Heterocyclic Organic Compound. CAS No. 104869-26-3. Molecular formula: C49H28F2N6O23S6.6Na. Mole weight: 1437.11. Purity: ≥95%. IUPACName: hexasodium;8-[[4-fluoro-3-[[3-[[3-[[2-fluoro-5-[(8-oxidoperoxysulfanyl-4,6-disulfonatonaphthalen-1-yl)carbamoyl]phenyl]carbamoyl]phenyl]carbamoylamino]benzoyl]amino]benzoyl]amino]naphthalene-1,3,5-trisulfonate. Canonical SMILES: C1=CC(=CC(=C1)NC(=O)NC2=CC=CC(=C2)C(=O)NC3=C(C=CC(=C3)C(=O)NC4=C5C(=CC(=CC5=C(C=C4)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])F)C(=O)NC6=C(C=CC(=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)[O-])S(=O)(=O)[O-])SOO[O-])F.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]. Product ID: ACM104869263. Alfa Chemistry ISO 9001:2015 Certified. Categories: NF-17DC.
NF 157
NF 157. Group: Biochemicals. Grades: Purified. CAS No. 104869-26-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NF279
NF279 is a potent selective and reversible P2X1 receptor antagonist, with an IC 50 of 19 nM. NF279 displays good selectivity over P2X2, P2X3 (IC 50=1.62 μM), P2X4 (IC 50 >300 μM). NF279 is a dual HIV-1 coreceptor inhibitor that interferes with the functional engagement of CCR5 and CXCR4 by Env [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 202983-32-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D0976.
NF 279
NF 279. Group: Biochemicals. Grades: Purified. CAS No. 202983-32-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NF 340
NF 340. Group: Biochemicals. Grades: Purified. CAS No. 202982-98-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
NF449
NF449. Group: Biochemicals. Alternative Names: 4, 4', 4'', 4'''-[Carbonylbis[imino-5, 1, 3-benzenetriylbis (carbonylimino) ]]tetrakis-1, 3-Benzenedisulfonic Acid Sodium Salt (1:8); 4, 4', 4'', 4'''-[Carbonylbis[imino-5, 1, 3-benzenetriylbis (carbonylimino) ]]tetrakis-1, 3-benzenedisulfonic Acid Octasodium Salt. Grades: Highly Purified. CAS No. 627034-85-9. Pack Sizes: 10mg. Molecular Formula: C41H32N6Na8O29S8, Molecular Weight: 1513.15. US Biological Life Sciences.
Worldwide
NF 449
NF 449. Group: Biochemicals. Grades: Purified. CAS No. 627034-85-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NF449 octasodium
NF449 octasodium is a highly potent P2X1 receptor antagonist, with IC50s of 0.28, 0.69, and 120 nM for rP2X1, rP2X1+5, P2X2+3, respectively. NF449 octasodium is a Gs?-selective G Protein antagonist. NF449 octasodium suppresses the rate of GTP[?S] binding to Gs?-s, inhibits the stimulation of adenylyl cyclase activity, and blocks the coupling of ?-adrenergic receptors to Gs[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 627034-85-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112461A.
NF 546
NF 546. Group: Biochemicals. Grades: Purified. CAS No. 1006028-37-0. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
NF-56-EJ40
NF-56-EJ40 is a potent, high-affinity, and highly selective human SUCNR1 (GPR91) antagonist with an IC50 of 25 nM and a Ki of 33 nM, and shows almost no activity towards rat SUCNR1. NF-56-EJ40 has high affinity for humanized rat SUCNR1 with a Ki value of 17.4 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2380230-73-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130246.
NF764
NF764 is a potent ?-catenin (CTNNB1) degrader. NF764 reduces CTNNB1 protein levels in a proteasome-dependent manner. NF764 can be used in the study of cancer[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 1 mg; 5 mg. Product ID: HY-161719.
NFAP
NFAP is an antimicrobial peptide found in Neosartorya fischeri (Aspergillus fischeri), and has antifungal activity. Synonyms: Neosartorya (Aspergillus) Fischeri Antifungal Protein. Grade: >98%.
Selective inhibitor of calcineurin-mediated dephosphorylation of nuclear factor of activated T cells (NFAT). Does not disrupt other calcineurin-dependent pathways. Inhibits NFAT activation and NFAT-dependent expression of endogenous cytokine genes in T cells. Group: Biochemicals. Grades: Purified. CAS No. 249537-73-3. Pack Sizes: 1mg. Molecular Formula: C75H118N20O22S, Sequence: MAGPHPVIVITGPHEE. US Biological Life Sciences.
Worldwide
NFAT Inhibitor
A selective inhibitor of calcineurin-mediated dephosphorylation of nuclear factor of activated T cells (NFAT). Synonyms: H-Met-Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu-OH; L-methionyl-L-alanyl-glycyl-L-prolyl-L-histidyl-L-prolyl-L-valyl-L-isoleucyl-L-valyl-L-isoleucyl-L-threonyl-glycyl-L-prolyl-L-histidyl-L-alpha-glutamyl-L-glutamic acid. Grade: >98%. CAS No. 249537-73-3. Molecular formula: C75H118N20O22S. Mole weight: 1683.93.
A cell-permeable, synthetic maleimido-conjugated VIVIT motif peptide (HPVIVIT) that acts as a potent bipartite inhibitor of Nuclear factor of activated T-cells (NFAT) (IC50=62nM). Blocks NFAT-calcineurin interaction by targeting two separate calcineurin docking motifs. Completely blocks NFAT dephosphorylation at 1mM. Determined to be more potent that Cyclosporine A and VIVIT peptide (MAGPHPVIVITGPHEE) in blocking NFAT activity. Also shown to blocks NFAT-mediated T-cell activation and vascular smooth muscle cell proliferation, thereby reducing neoimtima (new thickening of arterial wall) formation in mouse models of restenosis (repeat blocking of blood vessels). The biological half life of MCV1 has been estimated to be about 36 hours in COS-1 cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg. Molecular Formula: C??H??N??O??. US Biological Life Sciences.
Worldwide
N-feruloylglycine deacylase
Hydrolyses a range of L-amino acids from the cinnamoyl and substituted cinnamoyl series. Not identical with EC 3.5.1.14 aminoacylase. Group: Enzymes. Synonyms: N-feruloylglycine hydrolase. Enzyme Commission Number: EC 3.5.1.71. CAS No. 118731-84-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4462; N-feruloylglycine deacylase; EC 3.5.1.71; 118731-84-3; N-feruloylglycine hydrolase. Cat No: EXWM-4462.
N-Feruloyloctopamine
N-Feruloyloctopamine is a natural alkaloid found in the herbs of Datura arborea, it is an tyrosinase inhibitor. N-Feruloyloctopamine has antioxidant activity and can be used in food and medical industry. Uses: Antioxidant. Synonyms: trans-N-Feruloyl octopamine; OctopaMine, N-feruloyl-. Grade: >97%. CAS No. 66648-44-0. Molecular formula: C18H19NO5. Mole weight: 329.35.
N-Feruloyl Serotonin
N-Feruloylserotonin is a conjugated serotonin compound that has been identified as the antioxidative component from the seed of Carthamus tinctorius. N-Feruloylserotonin displayed protective effects on oxidative damage in rat pheochromocytoma cells. Group: Biochemicals. Alternative Names: N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-3-(4-hydroxy-3-methoxyphenyl)-2-propenamide; N-Feruloylserotonin; NSC 369502. Grades: Highly Purified. CAS No. 68573-23-9. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
NFF-2
A quenched fluorescence substrate for MMPs. Group: Fluorescence/luminescence spectroscopy.
NFF-3
NFF-3 is a fluorogenic substrate for matrix metalloproteinases (MMPs). NFF-3 is hydrolyzed rapidly by MMP-3 (kcat/Km = 218,000 s-1*M-1) and slowly by MMP-9 (kcat/Km = 10,100 s-1*M-1) with no significant hydrolysis by MMP-1 or MMP-2, therefore it can be used to differentiate MMP-3 activity from that of other MMPs. Synonyms: Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2; ((7-Methoxycoumarin-4-yl)acetyl)arginyl-prolyl-lysyl-prolyl-valyl-glutamyl-norvalyl-tryptophyl-arginyl-(2,4-dinitrophenyl)lysinamide; N2-((7-Methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl)-L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-valyl-L-alpha-glutamyl-L-norvalyl-L-tryptophyl-L-arginyl-N6-(2,4-dinitrophenyl)-L-lysinamide; 7-Methoxycoumarin-4-acetyl-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-(2,4-dinitrophenyl)Lysinamide. Grade: ≥95%. CAS No. 158584-09-9. Molecular formula: C78H110N22O20. Mole weight: 1675.84.
NF-κB-IN-11
NF-κB-IN-11 (Compound 3i) is a NF-κB inhibitor. NF-κB-IN-11 inhibits TNF-α induced activation of NF-κB pathway, and inhibits nuclear translocation of NF-κB. NF-κB-IN-11 down-regulates the expression levels of phosphor-IKK, IκBα, and NF-κB p65. NF-κB-IN-11 has anti-inflammatory activity, and alleviates dextran sulfate sodium-induced colitis in mice. NF-κB-IN-11 (p.o.) shows a MTD more than 1852 mg/kg in mice acute toxicity assay [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2768833-35-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155998.
NF-κB Signaling Compound Library
A unique collection of 560 compounds targeting NF-κB signaling for high throughput screening and high content screening; - Effective tool for research in NF-κB signaling and related drug screening; - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L3800. Categories: NF-κB Signaling Compounds Libraries.
A cell-permeable quinazoline derivative that blocks PMA/PHA-induced NF-kB activation in Jurkat cells (IC50=11nM), but has no effect on PKC kinase, and exhibits an anti-inflammatory effect on carrageenin-induced paw edema in rats (1mg/kg, i.p.). In addition, it is shown to inhibit the store-operated calcium entry (SOC) pathway possibly by targeting TRPC1 containing heteromeric channels in Huntington Disease (HD) neurons (SK-N-SH cells transfected with mutant Huntingtin Htt-138Q) at 300nM. It displays neuroprotective effects in YAC128 MSN mice neurons from glutamate toxicity dose-dependently from 30nM to 3uM, which is consistent with TRPC1 knocown effects, and attenuates the progressive decline in the climbing speed of the HD Drosophila, dose-dependently from 100uM to 400uM. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
N-Fluoro-4,6-bis(trifluoromethyl)pyridinium-2-sulfonate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-FLUORO-4,6-BIS(TRIFLUOROMETHYL)PYRIDINIUM-2-SULFONATE;N-FLUORO-4,6-BIS(TRIFLUOROMETHYL)PYRIDINIUM-2-SULPHONATE. Product Category: Heterocyclic Organic Compound. CAS No. 147541-03-5. Molecular formula: C7H2F7NO3S. Mole weight: 313.15. Product ID: ACM147541035. Alfa Chemistry ISO 9001:2015 Certified.
N-Fluoro Benzene sulfonimide
N-Fluoro Benzene sulfonimide. Group: Biochemicals. Grades: Highly Purified. CAS No. 133745-75-2. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C12H10FNO4S2. US Biological Life Sciences.
N-Fluoro-N'- (chloromethyl) triethylenediamine bis (tetrafluoroborate). Group: Biochemicals. Alternative Names: 1-Chloromethyl-4-fluoro-1, 4-diazoniabicyclo[2. 2. 2]octane bis (tetrafluoroborate); F-TEDA. Grades: Highly Purified. CAS No. 140681-55-6. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. Molecular Formula: C7H14B2ClF9N2. US Biological Life Sciences.
Worldwide
N-Fluoroperfluoropiperidine
N-Fluoroperfluoropiperidine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Piperidine, undecafluoro-;piperidine,undecafluoro-;undecafluoropiperidine;undecafluoro-piperidine;N-FLUOROPERFLUOROPIPERIDINE;N-Fluoroperfluoropiperidine 98%;N-Fluoroperfluoropiperidine98%;Perfluoropiperidine. Product Category: Heterocyclic Organic Compound. CAS No. 836-77-1. Molecular formula: C5F11N. Mole weight: 283.04. Purity: 0.96. IUPACName: 1,2,2,3,3,4,4,5,5,6,6-undecafluoropiperidine. Canonical SMILES: C1(C(C(N(C(C1(F)F)(F)F)F)(F)F)(F)F)(F)F. Density: 1.78g/cm³. Product ID: ACM836771. Alfa Chemistry ISO 9001:2015 Certified.
N-Fmoc-1,3-propanediamine hydrobromide
N-Fmoc-1,3-propanediamine hydrobromide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 9-Fluorenylmethyl N-(3-aminopropyl)carbamate hydrobromide. Appearance: Solid. CAS No. 352351-59-8. Molecular formula: C18H20N2O2·HBr. Mole weight: 377.28. Purity: 0.95. Product ID: ACM352351598. Alfa Chemistry ISO 9001:2015 Certified.
N-Fmoc-1,6-hexanediamine hydrobromide. Uses: Designed for use in research and industrial production. Product Category: Amine Salts. CAS No. 352351-56-5. Molecular formula: C18H23NO ¡¤ HC. Mole weight: 419.36. Product ID: ACM352351565. Alfa Chemistry ISO 9001:2015 Certified.