A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Ordesekimab (AMG 714; PRV-015) is a fully human IgG1κ anti- IL-15 ( Interleukin Related ) monoclonal antibody. The binding of Ordesekimab to IL-15 inhibits the interaction of IL-15 with the IL-2Rβ and common γ chain of the IL-15 receptor complex, but not with the IL-15Rα chain. Ordesekimab has the potential for study of nonresponsive celiac disease (NRCD) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG 714; PRV-015. CAS No. 879293-15-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99410.
Ordopidine
Ordopidine is a dopaminergic stabilizer. It can inhibit psychostimulant-induced hyperactivity and stimulate behaviour in states of hypoactivity. In May 2016, Phase-I clinical trials in Parkinson's disease in Germany was discontinued. Uses: Parkinson's disease. Synonyms: ACR 325; ACR325; ACR-325; 1-Ethyl-4-(2-fluoro-3-(methylsulfonyl)phenyl)piperidine. Grades: 98%. CAS No. 871351-60-9. Molecular formula: C14H20FNO2S. Mole weight: 285.38.
Oregano Extract
Oregano Extract. Applications: Used for health care products, dietary supplements, herb medecine and cosmetic industry. Group: Others. Synonyms: Oregano Extract; Origanum vulgare L. Purity: 4-10:1 by TLC. Appearance: Brown Yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Leaf. Species: Origanum vulgare L. Oregano Extract; Origanum vulgare L.; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-135.
Orelabrutinib, also known as ICP-022, is a potent, orally active, and irreversible Bruton's tyrosine kinase (BTK) inhibitor, being developed by InnoCare Pharma, for the treatment of chronic lymphocytic leukaemia. Group: Inhibitors. Alternative Names: Orelabrutinib; ICP-022; ICP022; ICP 022. CAS No. 1655504-04-3. Molecular formula: C26H25N3O3. Mole weight: 427.5. Appearance: Solid powder. Purity: >98%. IUPACName: 2-(4-phenoxyphenyl)-6-[1-(prop-2-enoyl)piperidin- 4-yl]pyridine-3-carboxamide. Canonical SMILES: O=C (C1=CC=C (C2CCN (C (C=C)=O)CC2)N=C1C3=CC=C (OC4=CC=CC=C4)C=C3)N. Catalog: ACM1655504043.
Orelabrutinib
Orelabrutinib (ICP-022) is a potent, orally active, and irreversible Bruton's tyrosine kinase (BTK) inhibitor with potential antineoplastic activity. Orelabrutinib prevents both the activation of the B-cell antigen receptor (BCR) signaling pathway and BTK-mediated activation of downstream survival pathways, inhibiting the growth of malignant B-cells that overexpress BTK [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ICP-022. CAS No. 1655504-04-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129390.
Orenetide is a GABA receptor antagonist. Synonyms: L-threonyl-L-lysyl-L-prolyl-L-arginyl-L-proline. CAS No. 1124168-43-9. Molecular formula: C26H47N9O7. Mole weight: 597.7.
Oreoch-1
Oreoch-1 is an antimicrobial peptide found in Oreochromis niloticus, and has antibacterial and antifungal activity. Synonyms: Phe-Ile-His-His-Ile-Ile-Gly-Gly-Leu-Phe-Ser-Val-Gly-Lys-His-Ile-His-Gly-Leu-Ile-His-Gly-His; oreochromicin-1; Oreochromicin I. Grades: ≥95%.
Oreoch-3
Oreoch-3 is an antimicrobial peptide found in Oreochromis niloticus (Nile tilapia), and has antibacterial and antifungal activity. Synonyms: oreochromicin-3; Oreochromicin III. Grades: >98%.
Orexin 2 Receptor Agonist
N- [2- [3- [ [5- [3- (dimethylcarbamoyl) phenyl] -2-methoxyphenyl] sulfonylamino] anilino] ethyl] -3-methylbenzamide is an orexin 2 receptor agonist that is potentially for the treatment of narcolepsy. Synonyms: MDK-5220; MDK 5220; MDK5220. Orexin2 receptor agonist; CHEMBL3623075; N- [2- [3- [ [5- [3- (dimethylcarbamoyl) phenyl] -2-methoxyphenyl] sulfonylamino] anilino] ethyl] -3-methylbenzamide; GTPL9305; SCHEMBL18138813. Grades: ≥98%. CAS No. 1796565-52-0. Molecular formula: C32H34N4O5S. Mole weight: 586.707.
Orexin 2 Receptor Agonist
Orexin 2 Receptor Agonist is a potent selective OX2R agonist with an EC 50 of 23 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1796565-52-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19320.
Orexin 2 Receptor Agonist 2
Orexin 2 Receptor Agonist 2 is a selective orexin 2 receptor agonist, extracted from patent WO2017135306A1, example 16 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2114324-60-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138695.
Orexin A (1-15) (free acid)
Orexin A (1-15) (free acid) is the N-terminal segment of orexin A and contains two disulfide bonds. Synonyms: Hypocretin-1 (1-15) (Human, Mouse, Rat); Pyr-Pro-Leu-Pro-Asp-Cys-Cys-Arg-Gln-Lys-Thr-Cys-Ser-Cys-Arg-OH (Disulfide bridge: Cys6-Cys12, Cys7-Cys14). Grades: ≥95%. CAS No. 2022956-49-4. Molecular formula: C67H109N23O22S4. Mole weight: 1717.01.
Orexin A (16-33)
Orexin A (16-33) lacks the disulfide bridge of orexin A, but retains part of the full-length OXA/OXB activity. It has been used in place of intact neuropeptides. Synonyms: Hypocretin-1 (16-33) (Human, Mouse Rat); H-Leu-Tyr-Glu-Leu-Leu-His-Gly-Ala-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Leu-NH2; L-leucyl-L-tyrosyl-L-alpha-glutamyl-L-leucyl-L-leucyl-L-histidyl-glycyl-L-alanyl-glycyl-L-asparagyl-L-histidyl-L-alanyl-L-alanyl-glycyl-L-isoleucyl-L-leucyl-L-threonyl-L-leucinamide; OXA 16-33. Grades: ≥95%. CAS No. 1374694-00-4. Molecular formula: C85H136N24O23. Mole weight: 1862.16.
Orexin A (human, rat, mouse)
Orexin A (human, rat, mouse) (Hypocretin-1 (human, rat, mouse)), a 33 amino acid excitatory neuropeptide, orchestrates diverse central and peripheral processes. Orexin A (human, rat, mouse) binds and activates two types of G protein-coupled receptors, the orexin-1 receptor ( OX1R ) and the orexin-2 receptor ( OX2R ). Orexin A (human, rat, mouse) has a role in the regulation of feeding behavior. Orexin A (human, rat, mouse) is an effective anti-nociceptive and anti-hyperalgesic agent in mice and rats [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: Hypocretin-1 (human, rat, mouse). CAS No. 205640-90-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-106224.
Orexin A (human, rat, mouse)
An orexin receptors agonist. It can stimulate feeding following central administration. Grades: 95%. CAS No. 205640-90-0. Molecular formula: C152H243N47O44S4. Mole weight: 3561.12.
Orexin B human
An orexin receptors agonist. It can stimulate feeding following central administration. Synonyms: Human orexin B. Grades: ≥95% by HPLC. CAS No. 205640-91-1. Molecular formula: C123H212N44O35S. Mole weight: 2899.36.
Orexin B (rat, mouse)
An orexin receptors agonist. It can stimulate feeding following central administration. Synonyms: Rat orexin B; Orexin B (mouse); H-Arg-Pro-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Asn-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2; L-arginyl-L-prolyl-glycyl-L-prolyl-L-prolyl-glycyl-L-leucyl-L-glutaminyl-glycyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminyl-L-alanyl-L-asparagyl-glycyl-L-asparagyl-L-histidyl-L-alanyl-L-alanyl-glycyl-L-isoleucyl-L-leucyl-L-threonyl-L-methioninamide. Grades: ≥95% by HPLC. CAS No. 202801-92-1. Molecular formula: C126H215N45O34S. Mole weight: 2936.39.
Orexin B, rat, mouse
Orexin B, rat, mouse (Rat orexin B) is an endogenous agonist at Orexin receptor with K i s of 420 and 36 nM for OX1 and OX2, respectively. Uses: Scientific research. Group: Peptides. Alternative Names: Rat orexin B; Orexin B (mouse). CAS No. 202801-92-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1349.
Orexin receptor antagonist 2
Orexin receptor antagonist 2 (compound 30) is a potent orexin receptor antagonist with pK i s of 7.69 and 9.78. Orexin receptor antagonist 2 has the potential for the research of insomnia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1457940-75-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-136922.
Orexin receptor antagonist 3
Orexin receptor antagonist 3 (example 216) is an orexin receptor antagonist, which is extracted from the patent WO2011050198A1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1293282-55-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-137093.
Orfamide A
It is the major component of a family of cyclic lipopeptides produced by pseudomonas fluorescens pf-5. It is a moderate antifungal agent. It has a profound effect on the swarming motility of bacteria on agar surfaces. Synonyms: N-(3-hydroxy-1-oxotetradecyl)-L-leucyl-D-α-glutamyl-D-allothreonyl-D-alloisoleucyl-L-leucyl-D-seryl-L-leucyl-L-leucyl-D-seryl-L-valine, (10?3)-lactone. Grades: >98% by HPLC. CAS No. 939960-34-6. Molecular formula: C64H114N10O17. Mole weight: 1295.65.
Orfamide B
It is a component of a family of cyclic lipopeptides produced by pseudomonas fluorescens pf-5. Synonyms: N-(3-hydroxy-1-oxotetradecyl)-L-leucyl-D-α-glutamyl-D-allothreonyl-D-valyl-L-leucyl-D-seryl-L-leucyl-L-leucyl-D-seryl-L-valine, (10?3)-lactone. Grades: >98% by HPLC. CAS No. 939960-35-7. Molecular formula: C63H112N10O17. Mole weight: 1281.62.
Orforglipron
Orforglipron (LY3502970) (Compound 67) is an orally active agonist for Glucagon-like peptide-1 receptor ( GLP-1R ), which exhibits potency in ameliorates the type 2 diabete [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY3502970; GLP-1 receptor agonist 1. CAS No. 2212020-52-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-112185.
Org 12962 hydrochloride
Org 12962 hydrochloride is a 5-HT2C receptor agonist with pEC50 value of 7.01. It shows antiaversive effects in the anxiety models in rats. Synonyms: Org 12962 hydrochloride; Org12962 hydrochloride; Org-12962 hydrochloride; 1-[6-Chloro-5-trifluoromethyl)-2-pyridinyl]-piperazine hydrochloride. Grades: ≥99% by HPLC. CAS No. 210821-63-9. Molecular formula: C10H11ClF3N3.HCl. Mole weight: 302.12.
Org 12962 hydrochloride
Org 12962 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 210821-63-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Org 20599
Hoechst 33342 is a cell-permeable fluorescent DNA stain. It binds minor groove of AT-rich regions and is used to quantify DNA in viable cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 156685-94-8. Pack Sizes: 10mg, 50mg. Molecular Formula: C25H40ClNO3, Molecular Weight: 438.04. US Biological Life Sciences.
Worldwide
Org 20599
Org 20599 is an anesthetic steroid that has a modulatory effect on GABAA receptors. Org 20599 is a potential drug for the treatment of migraines and headaches. Synonyms: Org 20599 free base; Pregnan-20-one, 21-chloro-3-hydroxy-2-(4-morpholinyl)-, (2β,3α,5α)-; (2β,3α,5α)-21-Chloro-3-hydroxy-2-(4-morpholinyl)pregnan-20-one; 2-chloro-1-((2S,3S,5S,8R,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2-morpholinohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethan-1-one. Grades: ≥95% by HPLC. CAS No. 156685-94-8. Molecular formula: C25H40ClNO3. Mole weight: 438.04.
Org 24598
Org 24598 is a glial glycine transporter inhibitor with IC50 value of 6.9 nM. Synonyms: Org 24598; Org24598; Org-24598; N-Methyl-N-[(3R)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]-glycine. Grades: ≥98% by HPLC. CAS No. 372198-97-5. Molecular formula: C19H20F3NO3. Mole weight: 367.36.
Org 24598 lithium salt
Org 24598 lithium salt is a glycine transporter-1 (GlyT-1) inhibitor with pIC50 value of 6.9 for GlyT1. Synonyms: Org 24598 lithium salt; Org24598 lithium salt; Org-24598 lithium salt; N-Methyl-N-[(3R)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]-glycine lithium salt. Grades: ≥98% by HPLC. CAS No. 722456-08-8. Molecular formula: C19H19F3LiNO3. Mole weight: 373.3.
Org 24598 lithium salt
Org 24598 lithium salt. Group: Biochemicals. Grades: Purified. CAS No. 722456-08-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Org 25543 hydrochloride
Org 25543 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 495076-64-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Org 25543 hydrochloride
Org 25543 hydrochloride is a selective and irreversible GlyT2 inhibitor ( IC 50 : 16 nM). Org 25543 hydrochloride has analgesia effect. Org 25543 hydrochloride ameliorates mechanical allodynia after partial sciatic nerve ligation injury in mice [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 495076-64-7. Pack Sizes: 5 mg. Product ID: HY-107527.
Org 25543 hydrochloride
Org 25543 hydrochloride is a glycine transporter type 2 inhibitor with IC50 value of 16 nM. Synonyms: Benzamide, N-[[1-(dimethylamino)cyclopentyl]methyl]-3,5-dimethoxy-4-(phenylmethoxy)-, hydrochloride (1:1); Benzamide, N-[[1-(dimethylamino)cyclopentyl]methyl]-3,5-dimethoxy-4-(phenylmethoxy)-, monohydrochloride; 4-(benzyloxy)-N-((1-(dimethylamino)cyclopentyl)methyl)-3,5-dimethoxybenzamide hydrochloride; Org25543 hydrochloride; Org-25543 hydrochloride. Grades: ≥99% by HPLC. CAS No. 495076-64-7. Molecular formula: C24H32lN2O4.HCl. Mole weight: 448.98.
ORG 25935 hydrochloride
ORG 25935 hydrochloride is a potent and selective glycine transporter 1 (GlyT-1) or reuptake inhibitor intended for the treatment of neurological disorders such as schizophrenia. Uses: Treatment of neurological disorders. Synonyms: SCH-900435; SCH 900435; SCH900435; ORG 25935 hydrochloride; ORG25935 hydrochloride; ORG-25935 hydrochloride; rel-N-Methyl-N-[[(1R,2S)-1,2,3,4-tetrahydro-6-methoxy-1-phenyl-2-naphthalenyl]methyl]glycine hydrochloride. Grades: 99%. CAS No. 949588-40-3. Molecular formula: C21H25NO3.HCl. Mole weight: 375.89.
Org-26576
Org-26576 is a positive allosteric modulator of AMPA receptor. Org-26576 increases the anteroventral and laterodorsal thalamus, cingulate cortex, dentate gyrus and CA3 subfield of the hippocampus in mice. Org-26576 is potentially used for the treatment of depression and attention deficit disorder. Uses: Potential treatment of depression and attention deficit disorder. Synonyms: Org26576; Org 26576. CAS No. 1026791-61-6. Molecular formula: C11H12N2O2. Mole weight: 204.229.
Org 27569
Org 27569 is a potent CB1 receptor allosteric modulator, which increases agonist binding, yet blocks agonist-induced CB1 signaling. Uses: Scientific research. Group: Signaling pathways. CAS No. 868273-06-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13288.
Org 27569
Org 27569. Group: Biochemicals. Grades: Purified. CAS No. 868273-06-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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ORG-27569
Org 27569 is an allosteric modulator of cannabinoid CB1 receptor, induces a CB1 receptor state that is characterized by enhanced agonist affinity and decreased inverse agonist affinity. Synonyms: ORG-27569; ORG-27569; ORG-27569. Grades: 0.98. CAS No. 868273-06-7. Molecular formula: C24H28ClN3O. Mole weight: 409.95.
Org30958
ORG 30958 is a potent aromatase inhibitor in vivo. ORG 30958 proved to be devoid of antiestrogenic activity which indicates that the absence of cornification of vaginal epithelium in DHEAS-treated Hypex rats is induced by the inhibition of the biosynthesis of estrogens and not by an anti-estrogenic activity. Synonyms: (8S,9S,10S,13S,14S)-10-[(ethyldisulfanyl)methyl]-13-methyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione; 19-(ethyldithio)androst-4-ene-3,17-dione; ORG 30958; ORG-30958. CAS No. 99957-90-1. Molecular formula: C21H30O2S2. Mole weight: 378.59.
Org 37684
Org 37684. Group: Biochemicals. Grades: Purified. CAS No. 213007-95-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Org 37684
Org 37684 is a 5-HT2C receptor agonist. Synonyms: Org-37684; Org 37684; Org37684; (3S)-3-[(2,3--Dihydro-5-methoxy-1H-inden-4-yl)oxy]pyrrolidine hydrochloride. Grades: ≥98% by HPLC. CAS No. 213007-95-5. Molecular formula: C14H19NO2.HCl. Mole weight: 269.77.
Org 48762-0
Org 48762-0 is a p38 mitogen-activated protein kinase inhibitor. It can be used for the treatment of autoimmune disease and neuropathic pain. Synonyms: UR-13870, UR 13870, UR13870; 4,6-Bis(4-fluorophenyl)-2-methyl-5-(4-pyridyl)-2H-pyrazolo[3,4-b]pyridine; Org 48762-0. Grades: ≥98% by HPLC. CAS No. 755753-89-0. Molecular formula: C24H16F2N4. Mole weight: 398.41.
Organic Acid Metabolite Library of Standards
Organic Acid Metabolite Library of Standards. Group: Polypropylene (pp).