A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
ONO-4059 (hydrochloride) is the hydrochloride salt form of Tirabrutinib. ONO-4059 is a highly selective, orally bioavailable BTK inhibitor (IC50= 2.2 nM) and demonstrated therapeutic efficacy in a mouse arthritis model. Synonyms: (R)-6-amino-9-(1-(but-2-ynoyl)pyrrolidin-3-yl)-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purin-8-one hydrochloride; ONO-4059 HCl; ONO4059; ONO 4059; ONO-4059; GS 4059; GS-4059; GS4059; ONO-WG-307; Tirabrutinib. CAS No. 1439901-97-9. Molecular formula: C25H23ClN6O3. Mole weight: 490.95.
ONO 4817
ONO 4817 is a broad spectrum matrix metalloproteinase (MMPs) inhibitor. It shows antiangiogenic and anti-invasive properties on lung metastasis of murine renal cell carcinoma. Synonyms: ONO 4817; ONO4817; ONO-4817; N-[(1S,3S)-1-[(Ethoxymethoxy)methyl]-4-(hydroxyamino)-3-methyl-4-oxobutyl]-4-phenoxybenzamide. Grades: ≥99% by HPLC. CAS No. 223472-31-9. Molecular formula: C22H28N2O6. Mole weight: 416.47.
ONO 4817
ONO 4817. Group: Biochemicals. Grades: Purified. CAS No. 223472-31-9. Pack Sizes: 10mg. US Biological Life Sciences.
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ONO-5334
NO-5334 is cathepsin K inhibitor Ki values of 0.1 nM for human. It can improve bone strength by preferentially increasing cortical bone mass in ovariectomized rats. ONO-5334 can also inhibit N-terminal and C-terminal collagen crosslinks in serum and urine in postmenopausal women. In Feb 2012, Phase-II for Osteoporosis in European Union was discontinued. Uses: Osteoporosis. Synonyms: ONO-5334; ONO 5334; ONO5334. N-((S)-3-(2-((R,Z)-3,4-dimethylthiazolidin-2-ylidene)hydrazinyl)-2,3-dioxo-1-(tetrahydro-2H-pyran-4-yl)propyl)cycloheptanecarboxamide. Grades: 98%. CAS No. 868273-90-9. Molecular formula: C21H34N4O4S. Mole weight: 438.59.
ONO-6990554
ONO-6990554 is a dual inhibitor of Axl/Mer tyrosine kinase receptor (Axl/Mer IC50 = 0.002 mcM). Synonyms: ONO6990554; ONO 6990554.
ONO-7300243
ONO-7300243 is a novel, potent LPA1 (Lysophosphatidic Acid Receptor) antagonist (IC50 = 160 nM). In vitro ONO-7300243 showed good membrane permeability and good metabolic stability against rat liver microsomes. ONO-7300243 shows good efficacy in vivo. Synonyms: 2-[4-[[ (3, 5-dimethoxy-4-methylbenzoyl) - (3-phenylpropyl) amino]methyl]phenyl]acetic acid; ONO-7300243; ONO 7300243; ONO7300243. Grades: 99.52 %. CAS No. 638132-34-0. Molecular formula: C28H31NO5. Mole weight: 461.55.
ONO-7475
ONO-7475 is an Axl/Mer inhibitor that has been shown to inhibit the phosphorylation of AXL and Mer, and to suppress the growth of acute myeloid leukemia with FLT3 mutations (26, 27) and solid tumors. Synonyms: ONO 7475; ONO7475. Grades: >98%. CAS No. 1646839-59-9. Molecular formula: C32H26N4O6. Mole weight: 562.6.
ONO 8130
ONO 8130 is a prostanoid EP1 receptor antagonist. It can relieve bladder pain in mice with cyclophosphamide-induced cystitis. Synonyms: ONO8130; ONO 8130; ONO-8130; 4-[[[2,3-Dihydro-6-[(2-methylpropyl)[(4-methyl-2-thiazolyl)sulfonyl]amino]-1H-indene-5yl]oxy]methyl]benzoic acid. Grades: ≥98% by HPLC. CAS No. 459841-96-4. Molecular formula: C25H28N2O5S2. Mole weight: 500.63.
ONO-8711
ONO-8711 is a potent and selective competitive antagonist of the EP1 receptor. It reduces the risk of breast cancer, and inhibits its multiplicity and volume. Synonyms: ONO 8711; ONO8711; GTPL1920; (Z)-6-[(2R,3S)-3-[[(4-chloro-2-methylphenyl)sulfonylamino]methyl]-2-bicyclo[2.2.2]octanyl]hex-5-enoic acid. Grades: ≥98%. CAS No. 216158-34-8. Molecular formula: C22H30ClNO4S. Mole weight: 440.
ONO 8711 dicyclohexyl amine salt
ONO 8711 dicyclohexyl amine salt is a selective and competitive prostaglandin E (PGE) receptor EP1 antagonist with chemopreventive activity. It suppresses tumor incidence and proliferation in mouse models of cancer. Uses: Tumor suppressant. Synonyms: ONO 8711 dicyclohexyl amine salt; ONO8711 dicyclohexyl amine salt; ONO-8711 dicyclohexyl amine salt; dicyclohexylamine (Z) -6- ( (1S, 2R, 3R, 4S) -3- ( (4-chloro-2-methylphenylsulfonamido) methyl) bicyclo[2. 2. 2]octan-2-yl) hex-5-enoate. Grades: 98%. Molecular formula: C22H30ClNO4S.C12H23N. Mole weight: 621.31.
ONO-9270578
ONO-9270578 is a novel TRPC4/5 inhibitor. TRPC4 and TRC5 are both associated with modulation of anxiety and fear responses, thus ONO-9270578 has the anxiolytic effect. ONO-9270578 is the potential treatment of anxiety and depression. Uses: The potential treatment of anxiety and depression. Synonyms: ONO 9270578; ONO9270578.
ONO-AE 248
ONO-AE 248 is a selective EP3 receptor agonist with cardioprotective activity. ONO-AE 248 reduces myocardial infarction size by selectively binding to the EP3α receptor in mice. The cardioprotective effect of ONO-AE 248 is independent of hemodynamic effects. The mechanism of ONO-AE 248 may involve activation of protein kinase C and opening of K(ATP) channels [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 211230-67-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-12184.
ONO AE3 208
ONO AE3 208. Group: Biochemicals. Grades: Purified. CAS No. 402473-54-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
ONO-AE3-208
ONO-AE3-208 is an EP4 antagonist (Ki values are 1.3, 30, 790 and 2400 nM for EP4, EP3, FP and TP receptors respectively), which less potently affects EP3, FP, and TP receptors. Uses: An ep4 antagonist. Synonyms: ONO-AE3-208; ONO-AE-3-208; ONO-AE 3-208; AE 3-208; AE-3-208; AE3-208; ONO AE3 208 4-Cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]benzenebutanoic acid; 4-[4-cyano-2-[2-(4-fluoronaphthalen-1-yl)propanoylamino]phenyl]butanoic acid. Grades: ≥98%. CAS No. 402473-54-5. Molecular formula: C24H21FN2O3. Mole weight: 404.43.
ONO-AE3-208
ONO-AE3-208 is a selective and orally active EP4 receptor antagonist with a K i of 1.3 nM. ONO-AE3-208 shows less potently affects EP3, FP, and TP receptors (K i of 30 nM, 790 nM, and 2400 nM, respectively). ONO-AE3-208 suppresses cell invasion, migration, and metastasis of prostate cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AE 3-208. CAS No. 402473-54-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50901.
ONO EI-601
ONO EI-601, a sulfonylamine derivative, is one metabolite of ONO-5046 which is a neutrophil elastase inhibitor that could be effective against acute lung injury. Synonyms: Ono-EI-601; OnoEI601; Ono EI 601; Ono-EI 601; Ono EI-601; AC1MHG4J; N- (2- (p-Hydroxyphenylsulfonylamino) benzoyl) glycine; N- (2- ( ( (4-Hydroxyphenyl) sulfonyl) amino) benzoyl) glycine. Grades: 98%. CAS No. 155023-59-9. Molecular formula: C15H14N2O6S. Mole weight: 350.35.
Ononetin
Ononetin. Group: Biochemicals. Grades: Purified. CAS No. 487-49-0. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Ononetin
Ononetin is a TRPM3 channel blocker with IC50 value of 300 nM. Synonyms: 1-(2,4-Dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone. Grades: ≥98% by HPLC. CAS No. 487-49-0. Molecular formula: C15H14O4. Mole weight: 258.27.
Ononin
Ononin is an orally active isoflavone. Ononin inhibits the ERK/JNK/p38 and PI3K/Akt/mTOR pathways. Ononin regulates Apoptosis. Ononin has anti-tumor effects on laryngeal cancer and lung cancer. Ononin has neuroprotective effects. Ononin alleviates endoplasmic reticulum stress and diabetic nephropathy [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: Ononoside; Formononetin 7-O-β-D-glucopyranoside. CAS No. 486-62-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0270.
Ononin
Ononin. Group: Biochemicals. CAS No. 486-62-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Ononin (Fomononetin-7-O-glucoside)
Ononin (Fomononetin-7-O-glucoside). Group: Biochemicals. Alternative Names: Ononoside; Fomononetin-7-O-glucoside. Grades: Plant Grade. CAS No. 486-62-4. Pack Sizes: 20mg. Molecular Formula: C22H22O9, Molecular Weight: 430.405. US Biological Life Sciences.
Worldwide
ONO-RS-082
ONO-RS-082 is a reversible inhibitor of PLA2 and epinephrine. It has been shown to inhibit the substance P (SP)-induced histamine release in a concentration-dependent manner. Synonyms: 4-Chloro-2-[[(2E)-1-oxo-3-(4-pentylphenyl)-2-propen-1-yl]amino]benzoic Acid; (E)-4-chloro-2-[[1-oxo-3-(4-pentylphenyl)-2-propenyl]amino]benzoic Acid. Grades: ≥98%. CAS No. 99754-06-0. Molecular formula: C21H22ClNO3. Mole weight: 371.86.
Ono-RS-347
Ono-RS-347 is an SRS-A antagonist and a new leukotriene antagonists. Synonyms: Ono-RS-347; Ono RS-347; Ono RS 347; Ono-RS 347; 8-(4-(4-Phenylbutoxy)benzoyl)amino-2-(tetrazol-5'-yl)benzo-1,4-dioxane;4-(4-Phenylbutoxy)-N-[3-(2H-tetrazol-5-yl)-2,3-dihydro-1,4-benzodioxin-5-yl]benzamide;N-(3-(1H-tetrazol-5-yl)-2,3-dihydrobenzo[b][1,4]dioxin-5-yl)-4-(4-phenylbutoxy)benzamide. Grades: >98 %. CAS No. 103176-67-6. Molecular formula: C26H25N5O4. Mole weight: 471.51.
ONPG
ONPG is a colorimetric and spectrophotometric substrate for detection of β-galactosidase activity. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 2-Nitrophenyl β-D-galactopyranoside. CAS No. 369-07-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-15926.
Onradivir
Onradivir is a potent anti- influenza virus agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZSP1273. CAS No. 2200336-20-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145586.
Coupling reagent for synthesis of peptide and the formation of other amides. Synonyms: N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate; HSTU; O-(N-Succinimidyl)-1,1,3,3-tetramethyluronium hexafluorophosphate; AmbotzRL-1039; hexafluorophosphate. Grades: ≥ 99.5% (HPLC). CAS No. 265651-18-1. Molecular formula: C9H16F6N3O3P. Mole weight: 359.21.
O-[(N-Succinimidyl)succinyl-aminoethyl]-O'-methylpolyethylene glycol 2'000. Group: Poly(ethylene glycol) and poly(ethylene oxide). CAS No. 92451-00-8.
ONT-093
ONT-093 (formerly OC-144-093) is an orally bioavailable P-glycoprotein pump inhibitor, for the potential reversal of multidrug resistance in patients undergoing cancer chemotherapy. ONT-093 could inhibit P-gp and reverse multidrug resistance at nM concentrations with no effect on paclitaxel pharmacokinetics. Phase I trials of ONT-093 in normal human volunteers showed no dose-limiting toxicities at serum concentrations associated with biologic activity achieved with doses ranging from 300 to 500 mg. Synonyms: ONT 093; ONT093; (E)-4,4'-(2-(4-(3-ethoxyprop-1-en-1-yl)phenyl)-1H-imidazole-4,5-diyl)bis(N-isopropylaniline). CAS No. 216227-54-2. Molecular formula: C32H38N4O. Mole weight: 494.68.
Ontuxizumab
Ontuxizumab (MORAb-004) is a humanized IgG1/κ anti-endosialin (TEM-1 or CD248) monoclonal antibody with antitumor effects. Ontuxizumab can be used for the research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MORAb-004. CAS No. 946415-62-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99778.
NMS-1286937 is a potent, selective and orally available PLK1 inhibitor, with an IC 50 of 2 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NMS-1286937; NMS-P937. CAS No. 1034616-18-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15828.
Onvatilimab
Onvatilimab is a human monoclonal antibody that targets VISTA (V-domain immunoglobulin suppressor of T-cell activation). Onvatilimab inhibits VISTA signaling, abrogates the VISTA-induced suppression of T-lymphocyte-mediated immune responses, enhances cytotoxic T-cell responses against tumor cells and inhibits tumor cell growth. Synonyms: JNJ-61610588; JNJ 61610588; JNJ61610588. CAS No. 1969313-51-6.
ONX 0914
ONX 0914. Group: Biochemicals. Alternative Names: PR 957; N-[2-(4-Morpholinyl)acetyl]-L-alanyl-O-methyl-N-[(1S)-2-[(2R)-2-methyl-2-oxiranyl]-2-oxo-1-(phenylmethyl)ethyl]-L-tyrosinamide. Grades: Highly Purified. CAS No. 960374-59-8. Pack Sizes: 5mg. Molecular Formula: C31H40N4O7, Molecular Weight: 580.669999999999. US Biological Life Sciences.
Worldwide
ONX-0914
ONX 0914 is an immunoproteasome inhibitor with potential treatment applications in autoimmune disorders, such as rheumatoid arthritis, inflammatory bowel disease and lupus. ONX 0914 was designed to be a potent inhibitor of the immunoproteasome with minimal cross-reactivity for the constitutive proteasome. Recent evidence suggests that the immunoproteasome regulates the production of several inflammatory cytokines, including Tumor Necrosis Factor-α (TNF-α), Interleukin-6 (IL-6), IL-17, and IL-23. In preclinical models of rhematoid arthritis and lupus, ONX 0914 blocked progression of these diseases at well-tolerated doses. Preclinical studies are underway to evaluate the potential of ONX 0914 in the treatment of a range of autoimmune disorders. Uses: Proteasome inhibitors. Synonyms: ONX 0914; ONX0914; ONX-0914; PR957; PR-957; PR 957. Grades: >98%. CAS No. 960374-59-8. Molecular formula: C31H40N4O7. Mole weight: 580.6719.
Onychocin B
Onychocin B is a cyclic tetrapeptide that has been found in Onychocola sclerotica and it has calcium channel inhibitory activity. It inhibits the voltage-gated calcium (Cav) channel Cav1.2 with an IC50 value of 7.1 μM. Synonyms: Onychocin B; CHEMBL2063168; N-Methylcyclo(L-Phe-L-Ile-N-methyl L-Phe-L-Val-); (3S,6S,9S,12S)-6,12-dibenzyl-3-[(2S)-butan-2-yl]-1,7-dimethyl-9-propan-2-yl-1,4,7,10-tetrazacyclododecane-2,5,8,11-tetrone; 1380666-28-3; BDBM50389212. Grades: >95% by HPLC. Molecular formula: C31H42N4O4. Mole weight: 534.69.
O,O'-Bis[2-(N-Succinimidyl-succinylamino)ethyl]polyethylene glycol. Group: Poly(ethylene glycol) and poly(ethylene oxide). CAS No. 186020-53-1.
O, O'-Bis[2-(N-Succinimidyl-succinylamino)ethyl]Polyethylene glycol
O,O'-Bis[2-(N-Succinimidyl-succinylamino)ethyl]polyethylene glycol (NHS-PEG-NHS) is a cross-linking reagent. Uses: Biological field. Group: Polyethylene (pe). Alternative Names: α,ω-Bis-NHS-PEG, Di(N-succinimidyl) PEG-diacid, PEG-bis(N-succinimidyl succinate). CAS No. 186020-53-1. Molecular formula: average Mn 10,000.
O,O-Di-2-Naphthalenyl Ester Carbonothioic Acid
O,O-Di-2-Naphthalenyl Ester Carbonothioic Acid (Tolnaftate EP Impurity B) is a Tolnaftate impurity. Tolnaftate (T535400) functions as an antifungal agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 127084-74-6. Pack Sizes: 50mg, 100mg. Molecular Formula: C21H14O2S. US Biological Life Sciences.
Worldwide
O,O'-Di-2-pyridyl Thiocarbonate
O,O'-Di-2-pyridyl Thiocarbonate. Group: Biochemicals. Alternative Names: Di-2-Pyridyl Thionocarbonate; Thiocarbonic Acid O,O'-Di-2-pyridyl Ester. Grades: Highly Purified. CAS No. 96989-50-3. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. US Biological Life Sciences.
Worldwide
O,O-diacetyldaurisoline
O,O-diacetyldaurisoline. Group: Biochemicals. Grades: Plant Grade. CAS No. Pack Sizes: 10mg. US Biological Life Sciences.
O-O-Dibenzyl-(-)-actinonin (N4-Benzyloxy-N1-[1-(2-(S)-benzyloxy-methyl-pyrrolidine-1-carbonyl)-2-(S)-methyl-propyl]-2-(R)-pentylsuccinamide). Group: Biochemicals. Alternative Names: N4-Benzyloxy-N1-[1-(2-(S)-benzyloxy-methyl-pyrrolidine-1-carbonyl)-2-(S)-methyl-propyl]-2-(R)-pentylsuccinamide. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
O,O-Didesmethyl Omeprazole Sulfide
O,O-Didesmethyl Omeprazole Sulfide is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Synonyms: 4,5'-Di(desmethyl) Omeprazole Sulfide; 2-[[(4-Hydroxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1H-benzimidazol-5-ol. Grades: > 95%. CAS No. 176219-12-8. Molecular formula: C15H15N3O2S. Mole weight: 301.36.
O,O-Diethyl Dithiophosphate-13C4 Ammonium Salt
Labeled O,O-Diethyl Dithiophosphate. Used in the synthesis of novel phosphorothioates and phosphorodithioates. Group: Biochemicals. Alternative Names: Phosphorodithioic Acid O,O-Diethyl Ester-13C4 Ammonium Salt; Ammonium Ethyl Phosphorodithioate-13C4 ; Phosphorodithioic Acid O,O-Diethyl Ester-13C4 Ammonium Salt; Ammonium O,O-Diethyl Dithiophosphate-13C4 ; Ammonium O,O-Diethyl Phosphorodithioate-13C4 ; Ammonium Di-O-ethyl Dithiophosphate-13C4 ; Ammonium Diethyldithiophosphate-13C4 ; NF 133-13C4 ; O,O-Diethyl Ammonium Phosphorodithioate-13C4; O, O-Diethyl phosphorodithioic Acid-13C4 Ammonium Salt. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
O,O-Diethyl Thiophosphate Potassium Salt is used in bentazon-containing herbicidal mixture composition. It is also used in the toxicity study of Sulfotepp, an impurity of diazinon, an organophosphate pesticide used as an insecticide. Group: Biochemicals. Grades: Highly Purified. CAS No. 5871-17-0. Pack Sizes: 250mg, 500mg. Molecular Formula: C4H10KO3PS, Molecular Weight: 208.26. US Biological Life Sciences.
Worldwide
O,O-Dimethyl-d6
O,O-Dimethyl-d6. Group: Biochemicals. Alternative Names: Phosphorodithioic Acid O,O-Dimethyl-d6 Ester Ammonium Salt. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
O,O-Dimethyl Dithiophosphate-13C2 Ammonium Salt
Labeled dimethyl phosphorodithiolate derivatives used as insecticides. Group: Biochemicals. Alternative Names: Phosphorodithioic Acid O,O-Dimethyl Ester-13C2 Ammonium Salt. Grades: Highly Purified. CAS No. 1329610-82-3. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
O,O-Dimethyl Dithiophosphate Ammonium Salt
Dimethyl phosphorodithiolate derivatives used as insecticides. Group: Biochemicals. Alternative Names: Phosphorodithioic Acid O,O-Dimethyl Ester Ammonium Salt. Grades: Highly Purified. CAS No. 1066-97-3. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
o,o-Dimethylisomannide
Heterocyclic Organic Compound. Alternative Names: O,O-Dimethylisomannide. CAS No. 121693-37-6. Molecular formula: C12H24O10. Mole weight: 328.31296. Catalog: ACM121693376.
O,O-Dimethyl Methylphosphonate
O,O-Dimethyl Methylphosphonate is a commercially used preignition additive for gasoline, anti-foaming agent, plasticizer, stabilizer and antistatic agents. Group: Biochemicals. Alternative Names: Reoflam DMMP; DMMP; Dimethoxymethyl Phosphine Oxide; Dimethyl Methanephosphonate; Dimethyl Methylphosphonate; Fran TF 2000; Fyrol DMMP; Metaran; Methanephosphonic Acid Dimethyl Ester; Methylphosphonic Acid Dimethyl Ester; NSC 62240; Methylphosphonic Acid Dimethyl Ester; p-Methylphosphonic Acid Dimethyl Ester. Grades: Highly Purified. CAS No. 756-79-6. Pack Sizes: 25g. US Biological Life Sciences.