A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
A labeled metabolite of Erlotinib , an anti-cancer agent. Group: Biochemicals. Alternative Names: 2- [ [4- [ (3-Ethynylphenyl-d4) amino] -7- (2-methoxyethoxy) -6-quinazolinyl] oxy] ethanol; CP 373420. Grades: Highly Purified. CAS No. 1216420-11-9. Pack Sizes: 1mg. US Biological Life Sciences.
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OSI-7904L
OSI-7904L, also known as GW1843, OVI-237, GS7904L, is a potent, 3-methyl-substituted benzoquinazoline folate analog very specific for thymidylate synthase. Uses: Antineoplastic agents. Synonyms: GS7904L; GW1843; GW 1843; GW-1843; 1843U89; OVI-237; OVI 237; OVI237. CAS No. 139987-54-5. Molecular formula: C27H24N4O6. Mole weight: 500.51.
OSI-930
OSI-930 is an orally selective inhibitor of Kit , KDR and CSF-1R (c-Fms) with IC 50 s of 80 nM, 9 nM and 15 nM, respectively. OSI-930 also moderately inhibits Flt-1 , c-Raf , Lck and low activity against PDGFRα/β , Flt-3 and Abl. OSI-930 has antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 728033-96-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-10204.
OSI-930
OSI-930 is a selective thiophene-derived tyrosine kinase inhibitor with potential antineoplastic activity. Tyrosine kinase inhibitor OSI-930 inhibits stem cell factor receptor (c-Kit) and the vascular endothelial growth factor receptor 2 (VEGFR2), which may result in the inhibition of both tumor cell proliferation and tumor angiogenesis. Both c-Kit and VEGFR2 are overexpressed in a variety of cancers. Synonyms: OSI 930; OSI930. Grades: >98%. CAS No. 728033-96-3. Molecular formula: C22H16F3N3O2S. Mole weight: 443.444.
OSI-930
OSI-930 is a selective thiophene-derived tyrosine kinase inhibitor with potential antineoplastic activity. Tyrosine kinase inhibitor OSI-930 inhibits stem cell factor receptor (c-Kit) and the vascular endothelial growth factor receptor 2 (VEGFR2), which may result in the inhibition of both tumor cell proliferation and tumor angiogenesis. Both c-Kit and VEGFR2 are overexpressed in a variety of cancers. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). Uses: Designed for use in research and industrial production. Additional or Alternative Names: OSI-930; OSI 930; OSI930. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 728033-96-3. Molecular formula: C22H16F3N3O2S. Mole weight: 443.44. Purity: >98%. IUPACName: 3-((quinolin-4-ylmethyl)amino)-N-(4-(trifluoromethoxy)phenyl)thiophene-2-carboxamide. Canonical SMILES: O=C(C1=C(NCC2=CC=NC3=CC=CC=C23)C=CS1)NC4=CC=C(OC(F)(F)F)C=C4. Product ID: ACM728033963. Alfa Chemistry ISO 9001:2015 Certified. Categories: OSI-906.
O-sialoglycoprotein endopeptidase
An enzyme secreted by the bacterium Pasteurella haemolytica. Inhibited by EDTA (100 mM) and 1,10-phenanthroline. Type example of peptidase family M22. Group: Enzymes. Synonyms: glycoprotease; glycophorin A proteinase; glycoproteinase; sialoglycoprotease; sialoglycoproteinase. Enzyme Commission Number: EC 3.4.24.57. CAS No. 129430-53-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4339; O-sialoglycoprotein endopeptidase; EC 3.4.24.57; 129430-53-1; glycoprotease; glycophorin A proteinase; glycoproteinase; sialoglycoprotease; sialoglycoproteinase. Cat No: EXWM-4339.
Osilodrostat
Osilodrostat, also called as LCI699, is a modulator of 11-β-hydroxylase (IC50 = 2.5 nM), useful for treating a disorder ameliorated 11-β-hydroxylase inhibition, and a potent inhibitor of aldosterone synthase (IC50 = 0.7 nM). Synonyms: 4-[(5R)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl]-3-fluorobenzonitrile; LCI699. CAS No. 928134-65-0. Molecular formula: C13H10FN3. Mole weight: 227.24.
Osilodrostat
Osilodrostat (LCI699) is a potent, orally active11β-hydroxylase (CYP11B1) inhibitor with an IC 50 value of 35 nM. Osilodrostat is a potent, orally aldosterone synthase (CYP11B2) inhibitor with IC 50 values of 0.7 nM and 160 nM for human aldosterone synthase and rat aldosterone synthase, respectively. Osilodrostat inhibits aldosterone and corticosterone synthesis. Osilodrostat has blood pressure lowering ability. Osilodrostat can be used for research of Cushing syndrome (CS) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LCI699. CAS No. 928134-65-0. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16276.
Osilodrostat phosphate
Osilodrostat (LCI699) phosphate is a potent, orally active11β-hydroxylase (CYP11B1) inhibitor with an IC 50 value of 35 nM. Osilodrostat phosphate is a potent, orally aldosterone synthase (CYP11B2) inhibitor with IC 50 values of 0.7 nM and 160 nM for human aldosterone synthase and rat aldosterone synthase, respectively. Osilodrostat phosphate inhibits aldosterone and corticosterone synthesis. Osilodrostat phosphate has blood pressure lowering ability. Osilodrostat phosphate can be used for research of Cushing syndrome (CS) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LCI699 phosphate. CAS No. 1315449-72-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16276A.
Osimertinib
Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC 50 of 12 nM against L858R and 1 nM against L858R/T790M, respectively. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD-9291; Mereletinib. CAS No. 1421373-65-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15772.
Osimertinib
Cas No. 1421373-65-0.
Osimertinib mesylate
Osimertinib mesylate (AZD9291 mesylate) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC 50 of 12 nM against L858R and 1 nM against L858R/T790M. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD-9291 mesylate; Mereletinib mesylate. CAS No. 1421373-66-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15772A.
Osimertinib (Standard) is the analytical standard of Osimertinib. This product is intended for research and analytical applications. Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC 50 of 12 nM against L858R and 1 nM against L858R/T790M, respectively. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1421373-65-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15772R.
Osivelotor
Osivelotor is an orally effective small molecule. Osivelotor is an allosteric regulator of deoxyhemoglobin S (HbS). Osivelotor increases the affinity of HbS to oxygen, inhibits HbS polymerization, and thus prevents erythrocyte sickling in the blood. Osivelotor can be used for research of sickle cell disease (SCD) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GBT-601; GBT-021601. CAS No. 2417955-18-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148788.
OSMI-1 is an inhibitor of O-GlcNAc transferase (OGT) with IC50 value of 2.7 μM in vitro. It is cell-permeable and inhibits protein O-GlcNAcylation in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans. Synonyms: (2R)-N-(2-furylmethyl)-2-(2-methoxyphenyl)-2-{[(2-oxo-1,2-dihydroquinolin-6-yl)sulfonyl]amino}-N-(2-thienylmethyl)acetamide. Grades: ≥98%. CAS No. 1681056-61-0. Molecular formula: C28H25N3O6S2. Mole weight: 563.6.
OSMI-2
OSMI-2 (Compound 1b) is a cell-permeable O-linked N-acetylglucosamine transferase (OGT) inhibitor. Cells contain a large nuclear pool of partially spliced OGT transcript, and OSMI-2 increases detained intron splicing in cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2260542-60-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135784.
Osmin
Osmin is an antimicrobial peptide found in Osmia rufa (Red mason bee), and has antibacterial and antifungal activity. Synonyms: Gly-Phe-Leu-Ser-Ala-Leu-Lys-Lys-Tyr-Leu-Pro-Ile-Val-Leu-Lys-His-Val. Grades: ≥97%. Mole weight: 1924.20.
Osmium Catalyst supported on Magnetite (0.07-0.09mmol/g)
Osmium Catalyst supported on Magnetite (0.07-0.09mmol/g). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences.
Worldwide
Osmium(III) chloride
99.9% trace metals basis. Group: Biosensing and bioimaging.
Osmium Oxide Nanoparticles / Nanopowder. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Osmium Tetroxide. Product Category: Nanoparticles & Nanopowders. Appearance: Black or Yellow-Brown Crystalline Solid. CAS No. 12036-02-1. Molecular formula: OsO2. Mole weight: 222.229. Purity: 99%, 99.9%, 99.99%, 99.999%. IUPACName: tetraoxoosmium. Canonical SMILES: O=[Os](=O)(=O)=O. Density: 11400 kg/m-3. ECNumber: 244-058-7. Product ID: ACM12036021. Alfa Chemistry ISO 9001:2015 Certified.
Osmium tetroxide
Osmium tetroxide. Group: Biochemicals. Alternative Names: Osmic acid. Grades: Highly Purified. CAS No. 20816-12-0. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: O4Os. US Biological Life Sciences.
Worldwide
Osmium tetroxide ≥98.0% ACS
Osmium tetroxide ≥98.0% ACS. Group: Biochemicals. Grades: ACS Grade. CAS No. 20816-12-0. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
Worldwide
Osmium tetroxide solution
Osmium tetroxide solution. Group: Biochemicals. Grades: Highly Purified. CAS No. 20816-12-0. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: OsO4. US Biological Life Sciences.
Worldwide
Osmundacetone
Osmundacetone is a natural product isolated from Osmundae Rhizoma, with neuroprotective and anti-apoptotic effects. Osmundacetone has DPPH scavenging activity and protects neurological cell from oxidative stress. Osmundacetone can be a potential agent for the research of neurodegenerative diseases. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 37079-84-8. Molecular formula: C10H10O3. Mole weight: 178.18. Canonical SMILES: CC(/C=C/C1=CC=C(O)C(O)=C1)=O. Product ID: ACM37079848. Alfa Chemistry ISO 9001:2015 Certified.
Osocimab
Osocimab (BAY 1213790), an anti- FXIa antibody (K i =2.4 nM; EC 50 =0.2 nM). FXI inhibition may reduce the risk of thrombosis. Osocimab inhibits thrombin generation, and prolongs activated partial thromboplastin time. Osocimab exhibits anticoagulant effects [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BAY 1213790. CAS No. 2056878-75-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99794.
Osoresnontrine
Osoresnontrine (BI-409306) is a potent and selective PDE9A inhibitor, with an IC 50 of 52 nM, and shows weak activity against other PDEs, such as PDE1A ( IC 50 , 1.4 μM), PDE1C ( IC 50 , 1.0 μM), PDE2A, PDE3A, PDE4B, PDE5A, PDE6AB, PDE7A, and PDE10A ( IC 50 all > 10 μM); Osoresnontrine can be used in the research of memory enhancement in CNS disorders. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI-409306. CAS No. 1189767-28-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-112831.
Ospemifene
2-(4-(4-Chloro-1,2-diphenyl-but-1-enyl)phenoxy)ethanol, Deamino-hydroxytoremifene. selective estrogen receptor modulator for the prevention of osteoporosis. CAS No. 128607-22-7. Product ID: 8-01426. Molecular formula: C24H23O2Cl. Mole weight: 378.9. Source :
Ospemifene
Ospemifene is a non-estrogen selective estrogen receptor modulator (SERM), with K i s of 380 and 410 nM for estrogen receptor α (ERα) and ERβ , respectively. Ospemifene can be used for the research of vaginal atrophy and breast cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FC-1271a. CAS No. 128607-22-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0723.
Ospemifene E-Isomer
E-isomer of Ospemifene, which is a new selective non-hormonal estrogen receptor modulator that is used for the treatment of moderate to severe dyspareunia. Synonyms: 2-[4-[(1E)-4-chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]ethanol; 2-[4-[(1E)-4-chloro-1,2-diphenyl-1-butenyl]phenoxy]ethanol. Grades: > 95%. CAS No. 238089-02-6. Molecular formula: C24H23ClO2. Mole weight: 378.9.
Ospemifene Glucuronide
A metabolite of Ospemifene, which is a new selective non-hormonal estrogen receptor modulator that is used for the treatment of moderate to severe dyspareunia. Synonyms: Ospemifene O-β-D-Glucuronide; (2S,3S,4S,5R,6R)-6-(2-(4-((Z)-4-Chloro-1,2-diphenylbut-1-en-1-yl)phenoxy)ethoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid. Grades: > 95%. Molecular formula: C30H31ClO8. Mole weight: 555.03.
Ossamycin is a macrolide antibiotic produced by the strain of Str. hygroscopicus, Var. ossamyceticus C 8158. It has anti-fungal effect, and it has weaker anti-gram-positive bacterial effect. It inhibits L cells, Epstein-Barr ascites cancer cells, KB cells, sarcoma-180 cells, L-1210 cells, HeLa cells in cell culture with IC50s (μg/mL) of 0.007, 0.008, 0.005, 0.008, 0.003, 0.005, respectively. It has no antitumor effect in in vivo animal test. Synonyms: Antibiotic NK 154183B. Grades: ≥98%. CAS No. 11015-84-2. Molecular formula: C49H85NO14. Mole weight: 912.20.
Ostarine (MK-2866) is a selective androgen receptor modulator (SARMs) that regulates cardiomyocyte function, improves bone healing, regulates uterine function, and influences muscle tissue metabolism [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-2866; GTX-024; Enobosarm. CAS No. 841205-47-8. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg. Product ID: HY-13273.
Ostarine (MK-2866)
Ostarine, aslo known as Enobosarm, and MK-2866 and GTX-024, is selective androgen receptor modulator with anabolic activity. Selective androgen receptor modulator (SARM) GTx-024 is designed to work like testosterone, thus promoting and/or maintaining libido, fertility, prostate growth, and muscle growth and strength. Mimicking testosterone's action, this agent may increase lean body mass, thereby ameliorating muscle wasting in the hypermetabolic state of cancer cachexia.Ostarine (also known as GTx-024 and MK-2866) is an investigational selective androgen receptor modulator (SARM) from GTX, Inc for treatment of conditions such as muscle wasting and osteoporosis, formerly under development by Merck & Company. GTx and Merck had clinical development plans to evaluate Ostarine for the treatment of muscle loss in patients with COPD and for the treatment of chronic sarcopenia. They had a goal of initiating an Ostarine Phase II COPD clinical trial in the first quarter of 2010 and an Ostarine Phase IIb chronic sarcopenia clinical trial in 2010. Group: Biochemicals. Alternative Names: (2S) -3- (4-Cyanophenoxy) -N-[4-cyano-3- (trifluoromethyl) phenyl]-2-hydroxy-2-methylpropanamide; (S) -N- (4-Cyano-3- (trifluoromethyl) phenyl) -3- (4-cyanophenoxy) -2-hydroxy-2-methylpropanamide; MK-2866; GTX024; Enobosarm. Grades: Highly Purified. CAS No. 841205-47-8. Pack Sizes: 10mg, 25mg, 50mg. Molecular Formula: C19H14F3N3O3, Molecular Weight: 389.33. US Biological Life Sciences.
A unique collection of 320 osteogenesis related compounds for high throughput and high content screening; - Targets several signaling pathways, such as BMP-SMAD, Notch, MAPK, Wnt/β-catenin, Hedgehog, FGF, etc. ; - Effective tool for research in bone formation and related bone diseases, such as osteoporosis, bone tumor, etc. ; - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable. Uses: Scientific use. Product Category: L7900. Categories: Osteogenesis Compounds Libraries.
Osteogenic Growth Peptide, OGP
OGP is a short, naturally occurring 14-mer growth factor peptide found in serum at μM concentration. Synonyms: H-Ala-Leu-Lys-Arg-Gln-Gly-Arg-Thr-Leu-Tyr-Gly-Phe-Gly-Gly-OH; L-alanyl-L-leucyl-L-lysyl-L-arginyl-L-glutaminyl-glycyl-L-arginyl-L-threonyl-L-leucyl-L-tyrosyl-glycyl-L-phenylalanyl-glycyl-glycine. Grades: 95%. CAS No. 132996-61-3. Molecular formula: C68H110N22O18. Mole weight: 1523.74.
Osteogenic Growth Peptide, OGP
Osteogenic Growth Peptide, OGP is a short, naturally occurring 14-mer growth factor peptide found in serum at μM concentrations. Uses: Scientific research. Group: Peptides. CAS No. 132996-61-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1563.
Osteogenic Growth Peptide, OGP acetate
Osteogenic Growth Peptide, OGP acetate is a short, naturally occurring 14-mer growth factor peptide found in serum at μM concentrations. Osteogenic growth peptide OGP is a key factor in the mechanism of the systemic osteogenic response to local bone marrow injury. Molecular formula: C70H114N22O20. Mole weight: 1583.82.
The pentapeptide TRSAW is a potent inhibitor of osteoclastic bone resorption in vitro. Synonyms: (6S,9S,12S,15S)-15-((1H-indol-3-yl)methyl)-1-amino-6-((2S,3R)-2-amino-3-hydroxybutanamido)-9-(hydroxymethyl)-1-imino-12-methyl-7,10,13-trioxo-2,8,11,14-tetraazahexadecan-16-oic acid; pTH-rP (107-111) (human, bovine, dog, horse, mouse, rabbit, rat). CAS No. 138949-73-2. Molecular formula: C27H41N9O8. Mole weight: 619.67.
Osthenol
Osthenol is a hydroxycoumarin with antitumor-promoting, antifungal and antibacterial activity. Synonyms: 7-hydroxy-8-prenylcoumarin. Grades: 98%. CAS No. 484-14-0. Molecular formula: C14H14O3. Mole weight: 230.3.
Osthol
Osthol - Product ID: NST-10-29. Category: Coumarins. Alternative Names: Osthenol methylether. Purity: 98%. Test method: HPLC. CAS No. 484-12-8. Pack Sizes: 5g, 10g, 25g, 50g. Appearance: White to beige coloured Powder. Molecular formula: C15H16O3. Mole weight: 244.29. Storage: +2 +8 °C.
Osthol
Osthol. Group: Biochemicals. Alternative Names: Osthenol methylether. Grades: Plant Grade. CAS No. 484-12-8. Pack Sizes: 20mg. Molecular Formula: C15H16O3, Molecular Weight: 244.286. US Biological Life Sciences.
Worldwide
Osthole
Osthole (Osthol) is a natural antihistamine alternative. Osthole may be a potential inhibitor of histamine H 1 receptor activity. Osthole also suppresses the secretion of HBV in cells. Uses: Scientific research. Group: Natural products. Alternative Names: Osthol; NSC 31868. CAS No. 484-12-8. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-N0054.
Osthole
Osthole (Osthol) is a natural antihistamine alternative. Osthole may be a potential inhibitor of histamine H1 receptor activity. Osthole also suppresses the secretion of HBV in cells. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-Methoxy-8-(3-methyl-2-butenyl)-coumarin. Product Category: Inhibitors. Appearance: Powder. CAS No. 484-12-8. Molecular formula: C15H16O3. Mole weight: 244.29. Purity: 0.98. IUPACName: 7-Methoxy-8-(3-methylbut-2-enyl)chromen-2-one. Canonical SMILES: CC(=CCC1=C(C=CC2=C1OC(=O)C=C2)OC)C. Density: 1.126 g/ml. Product ID: ACM484128. Alfa Chemistry ISO 9001:2015 Certified.
Osthole
Osthole. Group: Biochemicals. Alternative Names: 7-Methoxy-8-(3-methyl-2-butenyl)coumarin. Grades: Highly Purified. CAS No. 484-12-8. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C15H16O3. US Biological Life Sciences.
Ostreogrycin A (Mikamycin A, Pristinamycin IIA, Stephylomycin M1, Streptogramin A, Syncothrecin A, Synergistin A1, Virginiamycin M1, Vernamycin A, Antibiotic 14752-2, Antibiotic E129A, Antibiotic PA 114A, Antibiotic 1745Z3A, Antibiotic 547C, Factor M)
Ostreogrycin A also commonly referred to as virginiamycin M1 or streptogramin A is the major component of the "virginamycin complex". In the 1950s this complex was independently discovered so many times the literature became highly confusing. Ostreogrycin A is a macrocyclic lactone antibiotic that acts syngeristically with the structurally unrelated cyclic depsipeptides more commonly known as the virginiamycins B (ostreogrycin B or streptogramin B) and S to inhibit peptide elongation. This is achieved by blocking formation of a peptide bond between the growing peptide chain (peptidyl-tRNA) linked to the 50S ribosome and aminoacyl-tRNA. Ostreogrycin A has proven to be highly active against Gram positive bacteria, particularly methicillin-resistant S. aureus. Group: Biochemicals. Alternative Names: Mikamycin A, Pristinamycin IIA, Stephylomycin M1, Streptogramin A, Syncothrecin A, Synergistin A1, Virginiamycin M1, Vernamycin A, Antibiotic 14752-2, Antibiotic E129A, Antibiotic PA 114A, Antibiotic 1745Z3A, Antibiotic 547C, Factor M. Grades: Highly Purified. CAS No. 21411-53-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Ostreogrycin B3
It is produced by the strain of Str. ostreogriseus NRRL 2558 (NCIB 8792). It has anti-gram positive bacterial activity, and Ostreogrycin A has stronger antibacterial activity than other components. Ostreogrycin A or G has synergistic antibacterial effect with each component of Ostreogrycin B. The Complex has protective effect on mice infected with bacteria by subcutaneous or oral administration. Synonyms: Virginiamycin-S1; N-(3-Hydroxypicolinoyl)-cyclo[L-Thr*-D-Abu-L-Pro-4-(dimethylamino)-N-methyl-L-Phe-4-oxo-5-hydroxy-L-Hpr-L-phenyl-Gly-]. CAS No. 31508-69-7. Molecular formula: C45H54N8O11. Mole weight: 882.96.