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| Product | Description | |
|---|---|---|
| Oroxylin A | Oroxylin A is a natural active flavonoid with strong anticancer effects.IC50 value:Target:In vitro: Oroxylin A suppressed the MDM2-mediated degradation of p53 via downregulating MDM2 transcription in wt-p53 cancer cells. Oroxylin A remarkably reduced the generation of lactate and glucose uptake under hypoxia in HepG2 cells, inhibited HIF-1α expression and its stability. Oroxylin A promotes superoxide dismutase (SOD2) gene expression through SIRT3-regulated DNA-binding activity of FOXO3a and increases the activity of SOD2 by promoting SIRT3-mediated deacetylation.In vivo: Oroxylin A inhibited the tumor growth of nude mice-inoculated MCF-7 or HCT116 cells. The expression of MDM2 protein in tumor tissue was downregulated by oroxylin A as well. Group: Inhibitors. CAS No. 480-11-5. Molecular formula: C16H12O5. Mole weight: 284.26. Appearance: Solid. Purity: 0.9987. Canonical SMILES: O=C1C=C (C2=CC=CC=C2)OC3=CC (O)=C (OC)C (O)=C13. Catalog: ACM480115. |  |
| Oroxylin A | Oroxylin A is an active flavonoid compound with strong anti-cancer effects. Oroxylin A inhibits the IL-6/STAT3 pathway and NF-κB signaling, inhibits cell proliferation and induces apoptosis. Oroxylin A inhibits colitis-related carcinogenesis [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Baicalein 6-methyl ether; 6-Methoxybaicalein. CAS No. 480-11-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0560. |  |
| Oroxylin A 7-O-glucuronide | Oroxylin A 7-O-glucuronide is a highly valuable constituent harnessed in the biomedical sector, showcasing profound anti-inflammatory and antitumor attributes in studying cancer and maladies linked to inflammation. Uses: Antioxidant. Synonyms: Oroxyloside. Grades: >98%. CAS No. 36948-76-2. Molecular formula: C22H20O11. Mole weight: 460.39. |  |
| Oroxyloside (Oroxylin A 7-glucuronide) | Oroxyloside (Oroxylin A 7-glucuronide). Group: Biochemicals. Alternative Names: Oroxylin A 7-glucuronide. Grades: Plant Grade. CAS No. 36948-76-2. Pack Sizes: 5mg. Molecular Formula: C22H20O11, Molecular Weight: 460.387999999999. US Biological Life Sciences. |  Worldwide |
| Orphan GPCR SP9155 Agonist P518 (human) | It is a hypothalamic neuropeptide of the RFamide family of peptides with orexigenic activity and is an endogenous ligand of the orphan G protein-coupled receptor GPR103. Synonyms: P518 (human); Orphan G-Protein Coupled Receptor SP9155 Agonist Peptide P518 (human); 26Rfa, Hypothalamic Peptide, human; H-Thr-Ser-Gly-Pro-Leu-Gly-Asn-Leu-Ala-Glu-Glu-Leu-Asn-Gly-Tyr-Ser-Arg-Lys-Lys-Gly-Gly-Phe-Ser-Phe-Arg-Phe-NH2; L-threonyl-L-seryl-glycyl-L-prolyl-L-leucyl-glycyl-L-asparagyl-L-leucyl-L-alanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-leucyl-L-asparagyl-glycyl-L-tyrosyl-L-seryl-L-arginyl-L-lysyl-L-lysyl-glycyl-glycyl-L-phenylalanyl-L-seryl-L-phenylalanyl-L-arginyl-L-phenylalaninamide. Grades: ≥95%. CAS No. 600171-68-4. Molecular formula: C127H195N37O37. Mole weight: 2832.13. | |
| Orphanin FQ (1-11) | Orphanin FQ is a NOP agonist and it shows analgesic properties. Synonyms: H-Phe-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-OH; L-phenylalanyl-glycyl-glycyl-L-phenylalanyl-L-threonyl-glycyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanine; 1-11-Orphanin FQ (pig); 1-11-Orphanin FQ (swine); Nociceptin (1-11). Grades: ≥98% by HPLC. CAS No. 178249-41-7. Molecular formula: C49H75N15O14. Mole weight: 1098.20. | |
| Orphanin FQ (1-11) | Orphanin FQ (1-11). Group: Biochemicals. Grades: Purified. CAS No. 178249-41-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Orphanin FQ (1-11) acetate | Orphanin FQ (1-11) acetate, the peptide fragment containing amino acids 1-11 of Nociceptin, is a potent agonist of the ORL1/KOR-3 receptor with a Ki of 55 nM. Orphanin FQ is a NOP agonist with analgesic effects. Synonyms: H-Phe-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-OH.CH3CO2H; L-phenylalanyl-glycyl-glycyl-L-phenylalanyl-L-threonyl-glycyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanine acetate; 1-11-Orphanin FQ (pig) acetate; 1-11-Orphanin FQ (swine) acetate. Grades: ≥95%. Molecular formula: C51H79N15O16. Mole weight: 1158.26. | |
| Orphenadrine | Orphenadrine ((±)-Orphenadrine) is a skeletal muscle relaxant and NMDA antagonist that also has antiparkinsonian, antihistamine, antitremor, antispasmodic, and analgesic effects. Orphenadrine inhibits the binding of [3H] MK-801 to the phencyclidine (PCP) binding site of the NMDA receptor. Orphenadrine is also an anticholinergic and cytochrome P450 (CYP) 2B inducer. Orphenadrine may exert pro-tumor effects, causing CAR nuclear translocation, resulting in microsomal reactive oxygen species (ROS) production and oxidative stress. Orphenadrine also exerts neuronal protection, protecting rat cerebellar granule cells (CGC) from 3-NPA-induced death and has inhibitory potential against neurodegenerative diseases mediated by NMDA receptor overactivation [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Orphenadrine. CAS No. 83-98-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-157959. | |
| Orphenadrine | Use as emulsifying agent, dispersing agent. Use as antistatic agent. Use as pharmaceutical ingredient (For reference only. Group: Non-ionic surfactants. Alternative Names: Ethanamine, N,N-dimethyl-2-((2-methylphenyl)phenylmethoxy)-. CAS No. 83-98-7. Molecular formula: C18H23NO. Mole weight: 269.38. Catalog: ACM83987. | |
| Orphenadrine | Orphenadrine is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects. Uses: Antiparkinson agents; muscarinic antagonists; muscle relaxants, central; parasympatholytics. Synonyms: N, N-Dimethyl-2-[ (2-methylphenyl) phenylmethoxy]ethanamine. Grades: > 95%. CAS No. 83-98-7. Molecular formula: C18H23NO. Mole weight: 269.39. | |
| Orphenadrine citrate | Orphenadrine citrate is an orally active and non-competitive NMDA receptor antagonist (crosses the blood-brain barrier) with a K i of 6.0 μM. Orphenadrine citrate relieves stiffness, pain and discomfort due to muscle strains, sprains or other injuries. Orphenadrine citrate is also used to relieve tremors associated with parkinson's disease. Orphenadrine citrate has good neuroprotective properties, can be used in studies of neurodegenerative diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4682-36-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0369A. | |
| Orphenadrine Citrate | Orphenadrine Citrate is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects. Uses: Muscarinic antagonists. Synonyms: N, N-Dimethyl-2-[ (2-methylphenyl) phenylmethoxy]ethanamine Citrate Salt; Ethanamine, N,N-dimethyl-2-[(2-methylphenyl)phenylmethoxy]-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1); Ethylamine, N,N-dimethyl-2-[(o-methyl-α-phenylbenzyl)oxy]-, citrate (1:1); 2-Hydroxypropane-1,2,3-tricarboxylic acid; Dimethyl ([2-[ (2-methylphenyl) (phenyl)methoxy]ethyl])amine; Banflex; Norflex; Norflex (pharmaceutical); Plenactol; X-Otag; Orphenadrine Citrate Salt. Grades: >98%. CAS No. 4682-36-4. Molecular formula: C18H23NO.C6H8O7. Mole weight: 461.51. | |
| Orphenadrine Citrate Salt | Muscle relaxant (skeletal); antihistaminic. Group: Biochemicals. Alternative Names: N, N-Dimethyl-2- [ (2-methylphenyl) phenylmethoxy] ethanamine Citrate Salt; Banflex; Norflex; X-Otag. Grades: Highly Purified. CAS No. 4682-36-4. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| Orphenadrine-d3 Citrate Salt | Muscle relaxant (skeletal); antihistaminic. Group: Biochemicals. Alternative Names: N, N-Dimethyl-2- [ (2-methylphenyl) phenylmethoxy] ethanamine-d3 Citrate Salt; O-Mono methyl diphenhydramine-d3-Citrate Salt; BS-5930-d3; Biorphen-d3; Birocasipal-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Orphenadrine hydrochloride | A skeletal muscle relaxant used to treat drug-induced parkinsonism and to relieve pain from muscle spasm. Uses: Orphenadrine is an anticholinergic with a predominantly central effect and only a weak peripheral effect. Synonyms: N, N-dimethyl-2-[(2-methylphenyl)-phenylmethoxy]ethanamine; hydrochloride. Grades: > 98 %. CAS No. 341-69-5. Molecular formula: C18H23NO · HCl. Mole weight: 305.84. | |
| Orphenadrine Impurity C HCl | An impurity of Orphenadrine, which is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects. Synonyms: 2-[(2-Methylphenyl)phenylmethoxy]-ethanamine Hydrochloride; 2-[(o-Methyl-α-phenylbenzyl)oxy]-ethylamine Hydrochloride. Grades: > 95%. CAS No. 17752-32-8. Molecular formula: C16H19NO HCl. Mole weight: 277.79. | |
| Orphenadrine N-oxide | An impurity of Orphenadrine, which is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects. Synonyms: N, N-Dimethyl-2-[ (2-methylphenyl) phenylmethoxy]ethanamine N-Oxide; N,N-Dimethyl-2-[(o-methyl-α-phenylbenzyl)oxy]ethylamine N-Oxide. Grades: > 95%. CAS No. 29215-00-7. Molecular formula: C18H23NO2. Mole weight: 285.39. | |
| Orphenadrine N-Oxide | A metabolite of Orphenadrine. Group: Biochemicals. Alternative Names: N, N-Dimethyl-2- [ (2-methylphenyl) phenylmethoxy] ethanamine N-Oxide; N, N-Dimethyl-2-[ (o-methyl-α -phenylbenzyl) oxy]ethylamine N-Oxide. Grades: Highly Purified. CAS No. 29215-00-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Orphenadrine Related Compound B | An impurity of Orphenadrine, which is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects. Synonyms: (R)-N-Ethyl-N,N-dimethyl-2-(phenyl(o-tolyl)methoxy)ethanaminium Chloride; USP Orphenadrine Related Compound B. Grades: > 95%. Molecular formula: C20H28NO. Cl. Mole weight: 333.9. | |
| Orris Root Extract | Extract obtained from Iris Florentina (Orris) roots. Contains 20% extract dissolved in water and glycerin. Has purifying, cleansing and moisturizing properties. Uses: Creams and lotions, bubble baths, cleansers and shampoos. Group: Skin actives. CAS No. 7732-18-5 / 56-81-5 / 90045-89-9 / 122-99-6. Appearance: Light yellow liquid, characteristic odor. Catalog: CI-SC-0901. | |
| orsellinate decarboxylase | This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. Group: Enzymes. Synonyms: orsellinate carboxy-lyase. Enzyme Commission Number: EC 4.1.1.58. CAS No. 9076-58-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4804; orsellinate decarboxylase; EC 4.1.1.58; 9076-58-8; orsellinate carboxy-lyase. Cat No: EXWM-4804. |  |
| orsellinate-depside hydrolase | The enzyme will only hydrolyse those substrates based on the 2,4-dihydroxy-6-methylbenzoate structure that also have a free hydroxy group ortho to the depside linkage. Group: Enzymes. Synonyms: lecanorate hydrolase. Enzyme Commission Number: EC 3.1.1.40. CAS No. 62213-12-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3467; orsellinate-depside hydrolase; EC 3.1.1.40; 62213-12-1; lecanorate hydrolase. Cat No: EXWM-3467. | |
| Orsellinic acid | Orsellinic acid is a compound produced by Lecanoric acid treated with alcohols. Lecanoric acid is a lichen depside isolated from a Parmotrema tinctorum specimen [1]. Uses: Scientific research. Group: Natural products. CAS No. 480-64-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N3126. | |
| Orsellinic acid | Orsellinic acid is from Chaetomium globosum endophytic. Orsellinic acid can block platelet activating factor (PAF)-mediated neuronal apoptosis without affecting G-protein coupled receptor (PAFR)-mediated neuroprotection, and it can effectively attenuate PAFR-independent neuronal apoptosis. It is a novel benzoquinone ring precursor for antroquinonol and 4-acetylantroquinonol B. It is formed from acetyl-coenzyme Q (CoQ) and malonyl-CoA via polyketide pathway. Synonyms: o-Orsellinic acid; 4,6-Dihydroxy-o-toluic acid. Grades: 99.0%. CAS No. 480-64-8. Molecular formula: C8H8O4. Mole weight: 168.15. | |
| Ortataxel | Ortataxel. Uses: For analytical and research use. Group: Impurity standards. CAS No. 186348-23-2. Molecular Formula: C44H57NO17. Mole Weight: 871.93. Catalog: APB186348232. |  |
| Ortataxel | Ortataxel, also known as IDN5109, is novel seimsynthetic taxane with potential anticancer activity. Ortataxel is characterized by its high tolerability, antitumor efficacy, ability to overcome multidrug resistance, and oral bioavailabilty. In in vitro experiments, IDN5109 showed antiproliferative effects against HNSCC cell lines. After treatment with IDN5109, Bcl-2 and Bcl-XL were down-regulated, Bax was up-regulated, and caspase-3 was activated. After treatment with IDN5109, concentrations of both VEGF and IL-8 in the culture supernatant of HNSCC cells decreased. In in vivo experiments, the oral administration of IDN5109 showed antitumor effects against HNSCC tumor xenografts. Immunohistochemistry showed that IDN5109 inhibited tumor angiogenesis and induced apoptosis in HNSCC cells, producing a decreased blood vessel density and increased apoptosis index. On the basis of these results, IDN5109 is useful as a chemotherapeutic agent against HNSCC. Uses: Antineoplastic agents. Synonyms: Bay-59-8862, Bay 59 8862; SB-T-101131; SB T 101131; 13-(N-tert-butoxycarbonyl-beta-isobutyisoserinyl)-14-hydroxy-baccatin-1,14-carbonate. CAS No. 186348-23-2. Molecular formula: C44H57NO17. Mole weight: 871.93. | |
| Orteronel | Orteronel. Group: Biochemicals. Alternative Names: TAK-700; 6- [ (7S) -6, 7-Dihydro-7-hydroxy-5H-pyrrolo [1, 2-c] imidazol-7-yl] -N- methyl -2-naphthalene carboxamide. Grades: Highly Purified. CAS No. 566939-85-3. Pack Sizes: 5mg. Molecular Formula: C18H17N3O2, Molecular Weight: 307.35. US Biological Life Sciences. | Worldwide |
| Orteronel | Orteronel (TAK-700) is a highly selective inhibitor of human 17,20-lyase (CYP17) with IC 50 of 38 nM, and exhibits >1000-fold selectivity over other CYPs such as 11-hydroxylase and CYP3A4 [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-700. CAS No. 566939-85-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10505. | |
| Orteronel | Orterone (TAK-700) is an orally bioavailable non-steroidal androgen synthesis inhibitor of steroid 17alpha-monooxygenase (17,20 lyase) with potential antiandrogen activity. TAK-700 binds to and inhibits the steroid 17alpha-monooxygenase in both the testes and adrenal glands, thereby inhibiting androgen production. This may decrease androgen-dependent growth signaling and may inhibit cell proliferation of androgen-dependent tumor cells. The cytochrome P450 enzyme CYP17A1 (P450C17), localized to the endoplasmic reticulum (ER), exhibits both 17alpha-hydroxylase and 17,20-lyase activities, and plays a key role in the steroidogenic pathway that produces steroidal hormones, such as progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Synonyms: TAK-700; TAK 700; TAK700. Grades: >98%. CAS No. 566939-85-3. Molecular formula: C18H17N3O2. Mole weight: 307.353. | |
| Orthanilic acid (Aniline-2-sulfonic acid) | 100g Pack Size. Group: Building Blocks, Organics. Formula: C6H7NO3S. CAS No. 88-21-1. Prepack ID 84466713-100g. Molecular Weight 173.19. See USA prepack pricing. |  |
| Orthocaine | Anesthetic (topical). Group: Biochemicals. Alternative Names: 3-Amino-4-hydroxybenzoic Acid Methyl Ester; Orthoform; 1-Hydroxy-2-amino-4-carbomethoxybenzene; Aminobenz; Methyl 4-Hydroxy-3-aminobenzoate; Methyl 3-Amino-4-hydroxybenzoate; Methyl m-Amino-p-hydroxybenzoate; Orthocaine; Orthoderm. Grades: Highly Purified. CAS No. 536-25-4. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| Ortho Di Chloro Benzene (ODCB) | Heterocyclic Organic Compound. CAS No. 108-90-9. Catalog: ACM108909. | |
| ortho-Gliclazide | ortho-Gliclazide is the impurity of Gliclazide. Synonyms: Gliclazide impurity F; 1-(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-[(2-methylphenyl)sulphonyl]urea; N-[[(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-2-methylbenzenesulfonamide; 1-(3-Azabicyclo[3.3.0]oct-3-yl)-3-o-tolylsulphonylurea. Grades: > 95%. CAS No. 1076198-18-9. Molecular formula: C15H21N3O3S. Mole weight: 323.42. | |
| Orthohydroxyatorvastatin | . Uses: A metabolite of atorvastatin, a selective, competitive hmg-coa reductase inhibitor. atorvastatin is the only drug in its class specfically indicated for lowering both elevated ldl-cholesterol and triglycerides in patients with hypercholesterolemia. Synonyms: O-Hydroxyatorvastatin; 2-Hydroxy Atorvastatin; (3R,5R)-7-(2-(4-fluorophenyl)-4-(2-hydroxyphenylcarbamoyl)-5-isopropyl-3-phenyl-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoic acid. Grades: 95%. CAS No. 214217-86-4. Molecular formula: C33H35FN2O6. Mole weight: 574.649. | |
| ortho-Hydroxy Atorvastatin Calcium Salt | An impurity of Atorvastatin, a statin medication used to treat cardiovascular disease. Synonyms: 2-hydroxy Atorvastatin Calcium salt; Sodium (3R,5R)-7-(2-(4-fluorophenyl)-4-((2-hydroxyphenyl)carbamoyl)-5-isopropyl-3-phenyl-1Hp-pyrrol-1-yl)-3,5-dihydroxyheptanoate. Grades: > 95%. CAS No. 265989-46-6. Molecular formula: C66H68CaF2N4O12. Mole weight: 1187.36. | |
| Ortho-Hydroxy Atorvastatin Calcium Salt (Atorvastatin Impurity 13) | Ortho-Hydroxy Atorvastatin Calcium Salt (Atorvastatin Impurity 13). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1046118-41-5. Molecular Formula: C66H68CaF2N4O12. Mole Weight: 1187.36. Catalog: APB1046118415. | |
| Ortho-Hydroxy Atorvastatin Lactone | Ortho-Hydroxy Atorvastatin Lactone is metabolite of Atorvastatin, a selective, competitive inhibitor of HMG-CoA reductase. Synonyms: 2-Hydroxy Atorvastatin Lactone(EP); Atorvastatin 2-Hydroxy Lactone; 5-(4-Fluorophenyl)-N-(2-hydroxyphenyl)-2-(1-methylethyl)-4-phenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide; O-Hydroxy Atorvastatin Lactone. Grades: > 95%. CAS No. 163217-74-1. Molecular formula: C33H33FN2O5. Mole weight: 556.64. | |
| Ortho methylbenzyl alcohol | Ortho methylbenzyl alcohol. Uses: For analytical and research use. Group: Impurity standards. CAS No. 89-95-2. Molecular Formula: C8H10O. Mole Weight: 122.17. Catalog: APB89952. | |
| ortho-Mirabegron | ortho-Mirabegron is an isomer of Mirabegron, a potent bladder relaxant and reagent for diabetes remedy. Synonyms: 2-Amino-N-[2-[2-[[(2R)?-2-hydroxy-2-phenylethyl]?amino]?ethyl]?phenyl]?-4-thiazoleacetamide. CAS No. 1684452-80-9. Molecular formula: C21H24N4O2S. Mole weight: 396.51. | |
| Orthosulfamuron | Orthosulfamuron is a systemic post-emergence herbicide belonging to the sulfamoylurea class of herbicides. Sulfamoylurea herbicides act through inhibition of branch-chain amino acid biosynthesis in plants. Synonyms: ORTHOSULFAMURON; 1- (4, 6-Dimethoxypyrimidin-2-yl) -3-[2- (dimethylcarbamoyl) phenylsulfamoyl]urea. Grades: > 95%. CAS No. 213464-77-8. Molecular formula: C16H20N6O6S. Mole weight: 424.44. | |
| Orticumab | Orticumab (MLDL1278A) is an antibody targeting to oxidized or malondialdehyde-modified lipoprotein (LDL). Orticumab specifically inhibits oxidized low-density lipoproteins ( oxLDL ). Orticumab involves in modulation of autoimmune responses against oxLDL, improves atherosclerosis in animal model. Orticumab also can be used for research of psoriasis improvement [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MLDL1278A. CAS No. 1314241-10-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99793. | |
| Orvepitant | Orvepitant is a potent and selective Neurokinin-1 (NK1) antagonist. It may be potential therapeutic for the treatment of patients with major depressive disorder (MDD), anxiety and insomnia. It was developed by GlaxoSmithKline and is in clinical phase 2 trials. Uses: Orvepitant may be potential therapeutic for the treatment of patients with major depressive disorder (mdd), anxiety and insomnia. Synonyms: (2R,4S)-4-[(8aS)-6-oxo-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-2-yl]-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide;Orvepitant; GW-823296; GW823296; GW 823296; GW823296X. Grades: 95%. CAS No. 579475-18-6. Molecular formula: C31H35F7N4O2. Mole weight: 628.63. | |
| Orvepitant maleate | Orvepitant maleate is a neurokinin-1 (NK1) receptor antagonist developed for the treatment of depression and anxiety disease. Uses: Potential treatment of depression and anxiety disease. Synonyms: GW-823296B; GW823296B; GW 823296B; Orvepitant maleate; (2R,4S)-4-[(8aS)-6-oxo-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-2-yl]-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide (Z)-but-2-enedioic acid. Grades: 99%. CAS No. 579475-24-4. Molecular formula: C31H35F7N4O2.C4H4O4. Mole weight: 744.7. | |
| Orvepitant maleate | Orvepitant maleate (GW823296 maleate) is potent, selective, orally active and well-tolerated neurokinin-1 receptor (NK-1) antagonist with a pK i of 10.2 for human neurokinin-1 receptor. Orvepitant maleate can across the blood-brain barrier. Orvepitant maleate has the potential for depressive disorder and chronic refractory cough (CRC) treatment [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW823296 maleate. CAS No. 579475-24-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122347A. | |
| ORY-1001 dihydrochloride | ORY-1001 is a lysine specific demethylase 1 inhibitor under the development of Oryzon with IC50 value < 20nM. It selectively inhibits related FAD dependent aminoxidases (MAO-A/B, IL4I1, KDM1B> 100uM, SMOX 7uM). ORY-1001 can induce apoptosis in THP-1 and inhibit proliferation and colony formation of MV(4;11) (MLL-AF4) cells (EC50 <1nM). In THP-1 (MLL-AF9) cells, ORY-1001 results in a time-dose dependent me2H3K4 accumulation at KDM1A target genes and concomitant induction of differentiation markers. Synonyms: RG-6016; RG 6016; RG6016; ORY-1001 2HCl; ORY 1001 2HCl; ORY1001 2HCl; (1R,4R)-N1-((1R,2S)-2-phenylcyclopropyl)cyclohexane-1,4-diamine dihydrochloride. Grades:>98%. CAS No. 1431326-61-2. Molecular formula: C15H24Cl2N2. Mole weight: 303.27. | |
| oryzalexin D synthase | A heme-thiolate protein (cytochrome P-450). Isolated from Oryza sativa (rice). Oryzalexin D is a phytoalexin. Group: Enzymes. Synonyms: CYP76M8. Enzyme Commission Number: EC 1.14.13.193. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0793; oryzalexin D synthase; EC 1.14.13.193; CYP76M8. Cat No: EXWM-0793. | |
| oryzalexin E synthase | A heme-thiolate protein (cytochrome P-450). Isolated from Oryza sativa (rice). Oryzalexin E is a phytoalexin. Group: Enzymes. Synonyms: CYP76M6. Enzyme Commission Number: EC 1.14.13.192. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0792; oryzalexin E synthase; EC 1.14.13.192; CYP76M6. Cat No: EXWM-0792. | |
| Oryzalin | Oryzalin is a dinitroaniline herbicide, binding to plant tubulin and inhibits microtubule (MT) polymerization in vitro. Oryzalin depolymerizes MTs and prevented the polymerization of new MTs at all stages of the mitotic cycle [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 19044-88-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-147092. | |
| Oryzalin | Oryzalin is an antimitotic that has been used for doubling chromosomes. Uses: Classified as a dinitroaniline herbicide, oryzalin has been used to induce polypoloidy in vitro for several orchid species, rose, alocasia, miscanthus sinensis, apple, gerbera and many others. Group: Inhibitors. Alternative Names: 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide. CAS No. 19044-88-3. Molecular formula: C12H18N4O6S. Mole weight: 346.36 g/mol. Appearance: Dark Orange Crystalline. Purity: 0.9977. Canonical SMILES: O=S (C1=CC ([N+] ([O-])=O)=C (N (CCC)CCC)C ([N+] ([O-])=O)=C1) (N)=O. Catalog: ACM19044883. | |
| Oryzanol impurity 1 | Oryzanol impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 20972-10-5. Molecular Formula: C40H60O4. Mole Weight: 604.92. Catalog: APB20972105. | |
| Oryzanol impurity 10 | Oryzanol impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 20972-08-1. Molecular Formula: C39H56O4. Mole Weight: 588.87. Catalog: APB20972081. | |
| Oryzanol impurity 11 | Oryzanol impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 21238-33-5. Molecular Formula: C40H58O4. Mole Weight: 602.9. Catalog: APB21238335. | |
| Oryzanol impurity 12 | Oryzanol impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 469-36-3. Molecular Formula: C41H60O4. Mole Weight: 616.93. Catalog: APB469363. | |
| Oryzanol impurity 13 | Oryzanol impurity 13. Uses: For analytical and research use. Group: Impurity standards. CAS No. 11042-64-1. Molecular Formula: C40H58O4. Mole Weight: 602.9. Catalog: APB11042641. | |
| Oryzanol impurity 14 | Oryzanol impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106774-77-0. Molecular Formula: C38H58O4. Mole Weight: 578.88. Catalog: APB106774770. | |
| Oryzanol impurity 2 | Oryzanol impurity 2. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C40H60O4. Mole Weight: 604.92. Catalog: APB11882. | |
| Oryzanol impurity 3 | Oryzanol impurity 3. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C41H62O5. Mole Weight: 634.94. Catalog: APB11881. | |
| Oryzanol impurity 4 | Oryzanol impurity 4. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C42H64O4. Mole Weight: 632.97. Catalog: APB11884. | |
| Oryzanol impurity 5 | Oryzanol impurity 5. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C43H66O5. Mole Weight: 663. Catalog: APB11883. | |
| Oryzanol impurity 6 | Oryzanol impurity 6. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C41H60O4. Mole Weight: 616.93. Catalog: APB11885. | |
| Oryzanol impurity 7 | Oryzanol impurity 7. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C41H62O4. Mole Weight: 618.94. Catalog: APB11886. | |
| Oryzanol impurity 8 | Oryzanol impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 286011-30-1. Molecular Formula: C39H58O4. Mole Weight: 590.89. Catalog: APB286011301. | |
| Oryzanol impurity 9 | Oryzanol impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 20972-07-0. Molecular Formula: C38H56O4. Mole Weight: 576.86. Catalog: APB20972070. | |
| oryzin | A peptidase of family S8 (subtilisin family), not containing cysteine, that is the predominant extracellular alkaline endopeptidase of the mold Aspergillus oryzae.Identical or closely related enzymes are produced by A. flavus and A. sojae. Group: Enzymes. Synonyms: Aspergillus alkaline proteinase; aspergillopeptidase B; API 21; aspergillopepsin B; aspergillopepsin F; Aspergillus candidus alkaline proteinase; Aspergillus flavus alkaline proteinase; Aspergillus melleus semi-alkaline proteinase;. Enzyme Commission Number: EC 3.4.21.63. CAS No. 9074-7-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4154; oryzin; EC 3.4.21.63; 9074-07-1; Aspergillus alkaline proteinase; aspergillopeptidase B; API 21; aspergillopepsin B; aspergillopepsin F; Aspergillus candidus alkaline proteinase; Aspergillus flavus alkaline proteinase; Aspergillus melleus semi-alkaline proteinase; Aspergillus oryzae alkaline proteinase; Aspergillus parasiticus alkaline proteinase; Aspergillus serine proteinase; Aspergillus sydowi alkaline proteinase; Aspergillus soya alkaline proteinase; Aspergillus melleus alkaline proteinase; Aspergillus sulphureus alkaline proteinase; prozyme; P 5380; kyorinase; seaprose S; semi-alkaline protease; sumizyme MP; prozyme 10; onoprose; onoprose SA; protease P; promelase. Cat No: EXWM-4154. | |
| Oryzoxymycin | It is produced by the strain of Str. venezulae Var. oryzoxymyceticus. Oryzoxymycin has anti-gram-negative bacteria activity. Synonyms: BRN 2857392; 1,3-Cyclohexadiene-1-carboxylic acid, 6-amino-5-hydroxy-, 1-carboxyethyl ester, (5S-(1(S*), 5-alpha,6-beta))-. Grades: >98%. CAS No. 12640-81-2. Molecular formula: C10H13NO5. Mole weight: 227.21. | |
| Orziloben | Orziloben is a medium chain fatty acid (MCFA) analogue [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1555822-28-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156629. | |
| Os30 | Os30, a potent fourth-generation EGFR inhibitor, is a potent EGFRC797S-TK inhibitor with IC 50 values of 18 nM and 113 nM for EGFRDel19/T790M/C797S TK and EGFRL858R/T790M/C797S TK, respectively. Os30 can suppress EGFR phosphorylation, arrest at G1 phase and induce the apoptosis of KC-0116 (BaF3-EGFRDel19/T790M/C797S) cells. Os30 shows potent antitumor efficacy on non-small cell lung cancer (NSCLC) with EGFmRC797S mutation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2998928-68-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-155358. | |
| Osalmid | Osalmid is a ribonucleotide reductase small subunit M2 (RRM2) targeting compound; suppresses ribonucleotide reductase activity with an IC50 of 8.23 μM. Group: Inhibitors. CAS No. 526-18-1. Molecular formula: C13H11NO3. Mole weight: 229.23. Appearance: Solid. Purity: 0.98. Canonical SMILES: O=C(NC1=CC=C(O)C=C1)C2=CC=CC=C2O. Catalog: ACM526181. | |
| Osanetant | Osanetant (SR142801) is a selective NK3 receptor antagonist. Osanetant produces anxiolytic- and antidepressant-like effects and is researched for schizophrenia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SR142801. CAS No. 160492-56-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14551. | |
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